Table: Gene sets enriched in phenotype truncNotch (10 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Details ...	16	0.95	1.69	0.000	0.099	0.119	69	tags=13%, list=0%, signal=13%
2	HUMANCYC_GLUCONEOGENESIS	Details ...	17	0.93	1.69	0.000	0.056	0.135	312	tags=35%, list=2%, signal=36%
3	HUMANCYC_GLYCOLYSIS I	Details ...	20	0.85	1.61	0.006	0.246	0.616	312	tags=40%, list=2%, signal=41%
4	HUMANCYC_GLYCOLYSIS III	Details ...	21	0.85	1.59	0.004	0.296	0.790	312	tags=38%, list=2%, signal=39%
5	NCI_SIGNALING EVENTS MEDIATED BY PTP1B	Details ...	46	0.73	1.59	0.000	0.250	0.810	1955	tags=22%, list=11%, signal=24%
6	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS AND ENTNER-DOUDOROFF	Details ...	22	0.83	1.55	0.002	0.394	0.952	584	tags=41%, list=3%, signal=42%
7	NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS	Details ...	13	0.89	1.55	0.008	0.370	0.960	572	tags=15%, list=3%, signal=16%
8	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS	Details ...	39	0.72	1.53	0.018	0.443	0.991	312	tags=23%, list=2%, signal=23%
9	HUMANCYC_GLYCOLYSIS V	Details ...	18	0.84	1.53	0.006	0.399	0.991	312	tags=39%, list=2%, signal=40%
10	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION	Details ...	22	0.80	1.52	0.024	0.367	0.991	1398	tags=45%, list=8%, signal=49%
11	REACTOME_SIGNALING_BY_GPCR	Details ...	141	0.60	1.51	0.002	0.422	0.999	1378	tags=7%, list=7%, signal=8%
12	REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_	Details ...	93	0.63	1.51	0.010	0.390	0.999	3029	tags=13%, list=16%, signal=15%
13	INOH_MAMMALIAN NOTCH SIGNALING PATHWAY	Details ...	22	0.79	1.49	0.018	0.440	1.000	815	tags=36%, list=4%, signal=38%
14	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Details ...	53	0.68	1.49	0.018	0.432	1.000	3029	tags=13%, list=16%, signal=16%
15	NCI_EPHA FORWARD SIGNALING	Details ...	30	0.73	1.48	0.016	0.441	1.000	977	tags=10%, list=5%, signal=11%
16	INOH_NOTCH SECRETORY PATHWAY	Details ...	26	0.75	1.47	0.031	0.463	1.000	815	tags=27%, list=4%, signal=28%
17	INOH_CANONICAL NOTCH SIGNALING PATHWAY	Details ...	26	0.75	1.46	0.043	0.472	1.000	815	tags=27%, list=4%, signal=28%
18	INOH_NOTCH SECRETORY PATHWAY (MAMMAL)	Details ...	22	0.79	1.46	0.023	0.478	1.000	815	tags=36%, list=4%, signal=38%
19	REACTOME_GLUCONEOGENESIS	Details ...	11	0.87	1.45	0.035	0.488	1.000	883	tags=45%, list=5%, signal=48%
20	NCI_THROMBOXANE A2 RECEPTOR SIGNALING	Details ...	50	0.67	1.45	0.020	0.484	1.000	1442	tags=22%, list=8%, signal=24%
21	HUMANCYC_SERINE-ISOCITRATE LYASE PATHWAY		16	0.82	1.45	0.018	0.474	1.000	2051	tags=50%, list=11%, signal=56%
22	REACTOME_METABOLISM_OF_CARBOHYDRATES		70	0.62	1.43	0.021	0.553	1.000	933	tags=16%, list=5%, signal=16%
23	REACTOME_STRIATED_MUSCLE_CONTRACTION		14	0.83	1.42	0.050	0.591	1.000	2461	tags=36%, list=13%, signal=41%
24	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		16	0.78	1.41	0.055	0.594	1.000	3232	tags=31%, list=17%, signal=38%
25	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		17	0.78	1.41	0.050	0.585	1.000	3232	tags=29%, list=17%, signal=36%
26	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)		16	0.78	1.41	0.058	0.588	1.000	3232	tags=31%, list=17%, signal=38%
27	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		24	0.73	1.40	0.059	0.599	1.000	437	tags=13%, list=2%, signal=13%
28	REACTOME_GLUCOSE_METABOLISM		54	0.64	1.40	0.029	0.603	1.000	883	tags=15%, list=5%, signal=16%
29	HUMANCYC_ENTNER-DOUDOROFF PATHWAY II (NON-PHOSPHORYLATIVE)		12	0.82	1.39	0.086	0.598	1.000	584	tags=33%, list=3%, signal=34%
30	REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR		10	0.85	1.39	0.078	0.583	1.000	825	tags=20%, list=4%, signal=21%
31	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III		30	0.69	1.39	0.053	0.589	1.000	1345	tags=43%, list=7%, signal=47%
32	BIOCARTA_IL 2 SIGNALING PATHWAY		14	0.78	1.39	0.080	0.593	1.000	934	tags=36%, list=5%, signal=38%
33	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION		10	0.84	1.39	0.060	0.577	1.000	699	tags=40%, list=4%, signal=42%
34	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		40	0.65	1.38	0.067	0.566	1.000	1056	tags=15%, list=6%, signal=16%
35	REACTOME_COMPLEMENT_CASCADE		14	0.78	1.37	0.070	0.615	1.000	873	tags=14%, list=5%, signal=15%
36	REACTOME_PHASE_II_CONJUGATION		17	0.76	1.37	0.094	0.602	1.000	683	tags=18%, list=4%, signal=18%
37	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		16	0.78	1.37	0.075	0.588	1.000	3232	tags=31%, list=17%, signal=38%
38	REACTOME_SEMAPHORIN_INTERACTIONS		30	0.69	1.37	0.068	0.593	1.000	603	tags=20%, list=3%, signal=21%
39	REACTOME_INSULIN_SYNTHESIS_AND_SECRETION		66	0.59	1.35	0.063	0.674	1.000	3021	tags=24%, list=16%, signal=29%
40	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I		10	0.83	1.34	0.089	0.687	1.000	2005	tags=50%, list=11%, signal=56%
41	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES		11	0.82	1.33	0.086	0.738	1.000	1727	tags=55%, list=9%, signal=60%
42	HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS		11	0.81	1.33	0.110	0.724	1.000	1681	tags=45%, list=9%, signal=50%
43	BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR		36	0.64	1.33	0.098	0.711	1.000	699	tags=19%, list=4%, signal=20%
44	BIOCARTA_CLASSICAL COMPLEMENT PATHWAY		10	0.82	1.33	0.105	0.704	1.000	873	tags=20%, list=5%, signal=21%
45	BIOCARTA_SEGMENTATION CLOCK		22	0.71	1.32	0.120	0.744	1.000	597	tags=14%, list=3%, signal=14%
46	REACTOME_PEPTIDE_CHAIN_ELONGATION		45	0.61	1.31	0.105	0.768	1.000	3021	tags=24%, list=16%, signal=29%
47	NCI_ALPHA-SYNUCLEIN SIGNALING		32	0.65	1.30	0.120	0.774	1.000	2258	tags=28%, list=12%, signal=32%
48	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION		22	0.68	1.30	0.147	0.784	1.000	2501	tags=23%, list=13%, signal=26%
49	BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY		11	0.80	1.30	0.134	0.773	1.000	1703	tags=36%, list=9%, signal=40%
50	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION		47	0.61	1.30	0.088	0.759	1.000	3021	tags=26%, list=16%, signal=30%
51	HUMANCYC_SALVAGE PATHWAYS OF PURINE AND PYRIMIDINE NUCLEOTIDES		19	0.71	1.30	0.160	0.748	1.000	1237	tags=21%, list=7%, signal=23%
52	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT		10	0.81	1.30	0.117	0.737	1.000	873	tags=20%, list=5%, signal=21%
53	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS		12	0.77	1.29	0.130	0.736	1.000	2783	tags=17%, list=15%, signal=20%
54	REACTOME_CLASS_B_2__SECRETIN_FAMILY_RECEPTORS_		23	0.66	1.28	0.149	0.796	1.000	159	tags=4%, list=1%, signal=4%
55	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING		12	0.78	1.27	0.154	0.808	1.000	1626	tags=58%, list=9%, signal=64%
56	REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS		44	0.61	1.27	0.109	0.796	1.000	3021	tags=25%, list=16%, signal=30%
57	REACTOME_DIABETES_PATHWAYS		159	0.50	1.27	0.055	0.804	1.000	2655	tags=26%, list=14%, signal=30%
58	REACTOME_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS		11	0.75	1.26	0.182	0.815	1.000	2501	tags=27%, list=13%, signal=31%
59	BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE		18	0.70	1.26	0.164	0.816	1.000	1400	tags=17%, list=8%, signal=18%
60	REACTOME_METABOLISM_OF_NUCLEOTIDES		62	0.55	1.25	0.132	0.846	1.000	1894	tags=29%, list=10%, signal=32%
61	NCI_S1P4 PATHWAY		11	0.75	1.25	0.207	0.851	1.000	1647	tags=36%, list=9%, signal=40%
62	BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION		26	0.65	1.25	0.164	0.838	1.000	1850	tags=27%, list=10%, signal=30%
63	REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING		20	0.67	1.25	0.187	0.827	1.000	1378	tags=25%, list=7%, signal=27%
64	NCI_AMB2 INTEGRIN SIGNALING		48	0.58	1.24	0.153	0.825	1.000	2088	tags=23%, list=11%, signal=26%
65	BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS		21	0.67	1.24	0.209	0.818	1.000	825	tags=24%, list=4%, signal=25%
66	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		68	0.54	1.24	0.140	0.807	1.000	1442	tags=18%, list=8%, signal=19%
67	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING)		30	0.62	1.24	0.178	0.795	1.000	1230	tags=27%, list=7%, signal=29%
68	NCI_S1P1 PATHWAY		64	0.55	1.24	0.127	0.787	1.000	1570	tags=14%, list=8%, signal=15%
69	BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION		17	0.68	1.24	0.209	0.798	1.000	699	tags=18%, list=4%, signal=18%
70	REACTOME_PYRIMIDINE_METABOLISM		17	0.70	1.24	0.203	0.788	1.000	1727	tags=41%, list=9%, signal=45%
71	INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5)		10	0.76	1.23	0.199	0.799	1.000	831	tags=10%, list=4%, signal=10%
72	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	0.63	1.23	0.197	0.791	1.000	699	tags=20%, list=4%, signal=21%
73	NCI_VISUAL SIGNAL TRANSDUCTION: CONES		18	0.68	1.23	0.216	0.806	1.000	423	tags=6%, list=2%, signal=6%
74	BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING		34	0.59	1.22	0.190	0.820	1.000	840	tags=18%, list=5%, signal=18%
75	BIOCARTA_IL 3 SIGNALING PATHWAY		11	0.72	1.21	0.251	0.843	1.000	1463	tags=36%, list=8%, signal=39%
76	BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING		32	0.60	1.21	0.195	0.834	1.000	1163	tags=22%, list=6%, signal=23%
77	INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER		30	0.62	1.21	0.198	0.831	1.000	1230	tags=27%, list=7%, signal=29%
78	BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY		14	0.70	1.21	0.238	0.829	1.000	123	tags=7%, list=1%, signal=7%
79	BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS		10	0.74	1.21	0.244	0.819	1.000	2902	tags=30%, list=16%, signal=36%
80	REACTOME_MUSCLE_CONTRACTION		25	0.63	1.20	0.216	0.819	1.000	2461	tags=24%, list=13%, signal=28%
81	HUMANCYC_FATTY ACID BETA-OXIDATION II (CORE PATHWAY)		16	0.68	1.20	0.241	0.818	1.000	2965	tags=38%, list=16%, signal=45%
82	REACTOME_VIRAL_MRNA_TRANSLATION		46	0.57	1.20	0.183	0.811	1.000	174	tags=4%, list=1%, signal=4%
83	BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY		32	0.60	1.20	0.204	0.812	1.000	840	tags=16%, list=5%, signal=16%
84	NETPATH_IL2		61	0.53	1.20	0.182	0.809	1.000	1259	tags=20%, list=7%, signal=21%
85	BIOCARTA_ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM		41	0.57	1.20	0.187	0.809	1.000	452	tags=7%, list=2%, signal=7%
86	INOH_JAK DEGRADATION SIGNALING		24	0.62	1.19	0.227	0.805	1.000	1230	tags=29%, list=7%, signal=31%
87	BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION		25	0.62	1.19	0.245	0.798	1.000	452	tags=12%, list=2%, signal=12%
88	REACTOME_EUKARYOTIC_TRANSLATION_TERMINATION		46	0.56	1.19	0.189	0.789	1.000	174	tags=4%, list=1%, signal=4%
89	BIOCARTA_EPO SIGNALING PATHWAY		11	0.71	1.18	0.271	0.822	1.000	876	tags=27%, list=5%, signal=29%
90	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE)		197	0.45	1.17	0.135	0.845	1.000	423	tags=4%, list=2%, signal=4%
91	NCI_S1P2 PATHWAY		21	0.63	1.17	0.267	0.836	1.000	1378	tags=19%, list=7%, signal=21%
92	NCI_IL12 SIGNALING MEDIATED BY STAT4		28	0.59	1.17	0.252	0.854	1.000	699	tags=18%, list=4%, signal=19%
93	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II		22	0.62	1.17	0.267	0.849	1.000	2005	tags=27%, list=11%, signal=31%
94	BIOCARTA_IL 4 SIGNALING PATHWAY		11	0.71	1.16	0.291	0.848	1.000	991	tags=27%, list=5%, signal=29%
95	INOH_GENE EXPRESSION OF SOCS3 BY STAT DIMER		26	0.60	1.16	0.245	0.849	1.000	1230	tags=27%, list=7%, signal=29%
96	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)		26	0.60	1.16	0.238	0.843	1.000	1230	tags=27%, list=7%, signal=29%
97	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		15	0.66	1.16	0.286	0.838	1.000	2170	tags=40%, list=12%, signal=45%
98	BIOCARTA_CASPASE CASCADE IN APOPTOSIS		21	0.61	1.16	0.271	0.839	1.000	2074	tags=33%, list=11%, signal=37%
99	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		45	0.53	1.15	0.234	0.868	1.000	825	tags=16%, list=4%, signal=16%
100	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC)		22	0.60	1.15	0.265	0.861	1.000	307	tags=14%, list=2%, signal=14%
101	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		15	0.66	1.15	0.315	0.856	1.000	2170	tags=40%, list=12%, signal=45%
102	REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS		12	0.67	1.14	0.322	0.858	1.000	579	tags=8%, list=3%, signal=9%
103	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		28	0.58	1.14	0.265	0.853	1.000	1031	tags=21%, list=6%, signal=23%
104	INOH_TGF BETA RECEPTOR COMPLEX DEGRADATION SIGNALING		29	0.58	1.14	0.282	0.855	1.000	1230	tags=21%, list=7%, signal=22%
105	REACTOME_AXON_GUIDANCE		56	0.51	1.14	0.232	0.849	1.000	679	tags=16%, list=4%, signal=17%
106	NCI_ARF6 DOWNSTREAM PATHWAY		25	0.59	1.13	0.290	0.870	1.000	1850	tags=32%, list=10%, signal=35%
107	INOH_CYTOKINE RECEPTOR DEGRADATION SIGNALING		20	0.60	1.12	0.310	0.897	1.000	1230	tags=30%, list=7%, signal=32%
108	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING		12	0.68	1.12	0.349	0.891	1.000	1894	tags=50%, list=10%, signal=56%
109	BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS		19	0.61	1.12	0.328	0.889	1.000	1835	tags=26%, list=10%, signal=29%
110	REACTOME_EXOCYTOSIS_OF_ALPHA_GRANULE_		40	0.54	1.11	0.293	0.909	1.000	1861	tags=13%, list=10%, signal=14%
111	BIOCARTA_EICOSANOID METABOLISM		19	0.61	1.11	0.341	0.905	1.000	1126	tags=21%, list=6%, signal=22%
112	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS		12	0.66	1.11	0.370	0.898	1.000	2170	tags=42%, list=12%, signal=47%
113	NCI_S1P3 PATHWAY		24	0.59	1.11	0.334	0.896	1.000	1378	tags=21%, list=7%, signal=22%
114	HUMANCYC_ISOLEUCINE DEGRADATION III		13	0.64	1.11	0.340	0.892	1.000	1864	tags=38%, list=10%, signal=43%
115	REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS		19	0.60	1.10	0.346	0.906	1.000	2117	tags=32%, list=11%, signal=36%
116	REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE		17	0.59	1.10	0.342	0.900	1.000	951	tags=18%, list=5%, signal=19%
117	BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES		28	0.56	1.10	0.346	0.893	1.000	1835	tags=21%, list=10%, signal=24%
118	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM		109	0.45	1.10	0.243	0.901	1.000	2469	tags=29%, list=13%, signal=34%
119	BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY		29	0.56	1.10	0.351	0.895	1.000	437	tags=10%, list=2%, signal=11%
120	NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION		14	0.65	1.10	0.372	0.889	1.000	1031	tags=14%, list=6%, signal=15%
121	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS		10	0.65	1.10	0.392	0.883	1.000	1512	tags=10%, list=8%, signal=11%
122	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	0.57	1.09	0.380	0.899	1.000	2111	tags=23%, list=11%, signal=26%
123	REACTOME_REGULATION_OF_INSULIN_SECRETION		101	0.45	1.08	0.283	0.923	1.000	2469	tags=31%, list=13%, signal=35%
124	NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS		229	0.41	1.08	0.242	0.920	1.000	1850	tags=15%, list=10%, signal=17%
125	HUMANCYC_GLYCINE BETAINE DEGRADATION		10	0.65	1.07	0.393	0.925	1.000	2001	tags=30%, list=11%, signal=34%
126	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		14	0.61	1.07	0.394	0.934	1.000	1955	tags=29%, list=11%, signal=32%
127	REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION		90	0.45	1.07	0.334	0.928	1.000	2469	tags=33%, list=13%, signal=38%
128	BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME		10	0.66	1.07	0.434	0.922	1.000	1400	tags=40%, list=8%, signal=43%
129	HUMANCYC_PHOSPHOLIPASES		22	0.56	1.07	0.389	0.915	1.000	383	tags=5%, list=2%, signal=5%
130	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS		19	0.60	1.07	0.380	0.909	1.000	2117	tags=32%, list=11%, signal=36%
131	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	0.60	1.07	0.380	0.902	1.000	699	tags=19%, list=4%, signal=19%
132	NCI_EPHRINA-EPHA PATHWAY		40	0.51	1.07	0.342	0.898	1.000	63	tags=5%, list=0%, signal=5%
133	REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT		14	0.62	1.06	0.449	0.913	1.000	3450	tags=64%, list=19%, signal=79%
134	INOH_TGF BETA RECEPTOR I DEGRADATION SIGNALING		25	0.54	1.06	0.400	0.921	1.000	1230	tags=20%, list=7%, signal=21%
135	BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION		13	0.62	1.05	0.421	0.921	1.000	825	tags=23%, list=4%, signal=24%
136	NCI_HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK		57	0.47	1.05	0.363	0.921	1.000	1398	tags=18%, list=8%, signal=19%
137	REACTOME_HEMOSTASIS		147	0.42	1.05	0.319	0.928	1.000	1861	tags=14%, list=10%, signal=16%
138	HUMANCYC_SUPERPATHWAY OF CITRULLINE METABOLISM		11	0.61	1.03	0.469	0.971	1.000	2588	tags=36%, list=14%, signal=42%
139	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	0.57	1.03	0.442	0.983	1.000	1647	tags=35%, list=9%, signal=39%
140	INOH_B-RAF ACTIVATION SIGNALING		26	0.53	1.03	0.426	0.980	1.000	307	tags=12%, list=2%, signal=12%
141	NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2		62	0.46	1.03	0.397	0.975	1.000	1647	tags=16%, list=9%, signal=18%
142	NETPATH_TCR		105	0.42	1.02	0.386	0.977	1.000	2338	tags=25%, list=13%, signal=28%
143	BIOCARTA_PHOSPHOINOSITIDES AND THEIR DOWNSTREAM TARGETS		21	0.54	1.02	0.437	0.975	1.000	1398	tags=24%, list=8%, signal=26%
144	REACTOME_METABOLISM_OF_BILE_ACIDS_AND_BILE_SALTS		14	0.59	1.02	0.457	0.973	1.000	1512	tags=7%, list=8%, signal=8%
145	BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD		13	0.58	1.01	0.478	1.000	1.000	1158	tags=31%, list=6%, signal=33%
146	BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT		15	0.57	1.00	0.489	1.000	1.000	1625	tags=20%, list=9%, signal=22%
147	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	0.39	1.00	0.407	1.000	1.000	1632	tags=15%, list=9%, signal=16%
148	BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY		13	0.59	1.00	0.489	1.000	1.000	825	tags=23%, list=4%, signal=24%
149	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN)		175	0.39	1.00	0.429	1.000	1.000	423	tags=3%, list=2%, signal=3%
150	HUMANCYC_SALVAGE PATHWAYS OF PYRIMIDINE RIBONUCLEOTIDES		12	0.59	1.00	0.518	1.000	1.000	2323	tags=25%, list=12%, signal=29%
151	BIOCARTA_INTEGRIN SIGNALING PATHWAY		30	0.51	1.00	0.449	1.000	1.000	2229	tags=33%, list=12%, signal=38%
152	REACTOME_BIOLOGICAL_OXIDATIONS		46	0.47	1.00	0.446	0.997	1.000	1250	tags=11%, list=7%, signal=12%
153	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS		56	0.44	1.00	0.443	0.992	1.000	1570	tags=11%, list=8%, signal=12%
154	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		27	0.51	1.00	0.476	0.986	1.000	829	tags=15%, list=4%, signal=15%
155	BIOCARTA_INTRINSIC PROTHROMBIN ACTIVATION PATHWAY		22	0.53	0.99	0.480	0.990	1.000	2042	tags=14%, list=11%, signal=15%
156	NETPATH_TIE1_TEK		24	0.51	0.99	0.464	0.989	1.000	940	tags=17%, list=5%, signal=18%
157	REACTOME_PURINE_SALVAGE_REACTIONS		10	0.61	0.99	0.532	0.986	1.000	530	tags=20%, list=3%, signal=21%
158	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP)		175	0.39	0.99	0.468	0.986	1.000	423	tags=3%, list=2%, signal=3%
159	BIOCARTA_HEMOGLOBINS CHAPERONE		10	0.60	0.99	0.539	0.982	1.000	2955	tags=50%, list=16%, signal=59%
160	INOH_TGF BETA SIGNALING PATHWAY(THROUGH TAK1)		13	0.57	0.99	0.500	0.978	1.000	117	tags=8%, list=1%, signal=8%
161	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I		90	0.42	0.99	0.462	0.977	1.000	1470	tags=22%, list=8%, signal=24%
162	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE DEOXYRIBONUCLEOTIDES		11	0.59	0.98	0.518	0.972	1.000	1589	tags=36%, list=9%, signal=40%
163	REACTOME_PHASE_1_FUNCTIONALIZATION		10	0.60	0.98	0.525	0.967	1.000	1250	tags=20%, list=7%, signal=21%
164	NCI_EPHRIN B REVERSE SIGNALING		27	0.50	0.98	0.479	0.968	1.000	977	tags=19%, list=5%, signal=20%
165	REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT		53	0.45	0.98	0.470	0.967	1.000	174	tags=4%, list=1%, signal=4%
166	BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION		16	0.54	0.98	0.494	0.961	1.000	1647	tags=19%, list=9%, signal=21%
167	NCI_INSULIN PATHWAY		113	0.40	0.98	0.487	0.960	1.000	1850	tags=14%, list=10%, signal=16%
168	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP)		179	0.38	0.98	0.490	0.961	1.000	423	tags=3%, list=2%, signal=3%
169	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		196	0.38	0.97	0.500	0.960	1.000	1632	tags=15%, list=9%, signal=17%
170	BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY		32	0.48	0.97	0.467	0.955	1.000	1639	tags=19%, list=9%, signal=21%
171	REACTOME_REGULATORY_RNA_PATHWAYS		10	0.60	0.97	0.542	0.950	1.000	3450	tags=60%, list=19%, signal=74%
172	BIOCARTA_IL 6 SIGNALING PATHWAY		13	0.57	0.97	0.511	0.945	1.000	825	tags=15%, list=4%, signal=16%
173	NCI_ARF6 TRAFFICKING EVENTS		113	0.40	0.97	0.498	0.942	1.000	1850	tags=14%, list=10%, signal=16%
174	BIOCARTA_DOWNREGULATED OF MTA-3 IN ER-NEGATIVE BREAST TUMORS		18	0.54	0.97	0.503	0.939	1.000	794	tags=28%, list=4%, signal=29%
175	NCI_LPA RECEPTOR MEDIATED EVENTS		91	0.41	0.97	0.487	0.934	1.000	1456	tags=11%, list=8%, signal=12%
176	NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS		150	0.39	0.97	0.518	0.929	1.000	1567	tags=13%, list=8%, signal=14%
177	BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS		15	0.55	0.97	0.513	0.925	1.000	875	tags=20%, list=5%, signal=21%
178	NCI_PDGFR-BETA SIGNALING PATHWAY		51	0.44	0.97	0.491	0.923	1.000	1955	tags=16%, list=11%, signal=17%
179	NCI_INTEGRINS IN ANGIOGENESIS		63	0.43	0.97	0.496	0.919	1.000	1001	tags=11%, list=5%, signal=12%
180	INOH_B CELL RECEPTOR SIGNALING PATHWAY		68	0.42	0.97	0.507	0.916	1.000	1955	tags=24%, list=11%, signal=26%
181	NCI_ARF6 SIGNALING EVENTS		113	0.40	0.97	0.507	0.918	1.000	1850	tags=14%, list=10%, signal=16%
182	INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY		132	0.39	0.96	0.525	0.920	1.000	1632	tags=17%, list=9%, signal=18%
183	NETPATH_IFN-ALPHA		43	0.45	0.96	0.499	0.920	1.000	1567	tags=23%, list=8%, signal=25%
184	NCI_SIGNALING EVENTS MEDIATED BY PRL		21	0.52	0.96	0.523	0.920	1.000	307	tags=19%, list=2%, signal=19%
185	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING		17	0.54	0.96	0.554	0.930	1.000	18	tags=6%, list=0%, signal=6%
186	NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA		67	0.42	0.95	0.525	0.926	1.000	1398	tags=19%, list=8%, signal=21%
187	REACTOME__3___UTR_MEDIATED_TRANSLATIONAL_REGULATION		52	0.43	0.95	0.534	0.922	1.000	174	tags=4%, list=1%, signal=4%
188	REACTOME_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION		52	0.43	0.95	0.562	0.922	1.000	174	tags=4%, list=1%, signal=4%
189	CELLMAP_KITRECEPTOR		49	0.44	0.95	0.534	0.925	1.000	1684	tags=18%, list=9%, signal=20%
190	REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS		15	0.54	0.95	0.543	0.921	1.000	840	tags=20%, list=5%, signal=21%
191	HUMANCYC_SUPERPATHWAY OF GLYOXYLATE CYCLE		10	0.58	0.95	0.571	0.917	1.000	3193	tags=40%, list=17%, signal=48%
192	HUMANCYC_TRIACYLGLYCEROL DEGRADATION		12	0.57	0.95	0.568	0.920	1.000	3957	tags=25%, list=21%, signal=32%
193	NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES		43	0.44	0.94	0.544	0.919	1.000	349	tags=9%, list=2%, signal=9%
194	BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY		12	0.57	0.94	0.580	0.923	1.000	840	tags=25%, list=5%, signal=26%
195	INOH_GENE EXPRESSION OF SMAD7 BY R-SMAD:SMAD4		35	0.45	0.94	0.532	0.925	1.000	1230	tags=20%, list=7%, signal=21%
196	NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY		31	0.47	0.94	0.548	0.923	1.000	963	tags=23%, list=5%, signal=24%
197	REACTOME_ELECTRON_TRANSPORT_CHAIN		53	0.42	0.94	0.556	0.919	1.000	3111	tags=47%, list=17%, signal=56%
198	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		48	0.43	0.94	0.554	0.919	1.000	1955	tags=27%, list=11%, signal=30%
199	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS		19	0.51	0.93	0.542	0.918	1.000	1887	tags=26%, list=10%, signal=29%
200	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		32	0.46	0.93	0.555	0.917	1.000	2111	tags=22%, list=11%, signal=25%
201	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		32	0.47	0.93	0.558	0.913	1.000	1955	tags=34%, list=11%, signal=38%
202	BIOCARTA_STRESS INDUCTION OF HSP REGULATION		14	0.54	0.93	0.581	0.909	1.000	1433	tags=21%, list=8%, signal=23%
203	NCI_EPO SIGNALING PATHWAY		32	0.46	0.93	0.576	0.908	1.000	876	tags=16%, list=5%, signal=16%
204	REACTOME_SIGNALING_IN_IMMUNE_SYSTEM		136	0.38	0.93	0.592	0.911	1.000	1578	tags=13%, list=8%, signal=14%
205	BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY		24	0.48	0.93	0.561	0.908	1.000	963	tags=17%, list=5%, signal=18%
206	BIOCARTA_G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS		10	0.57	0.93	0.594	0.905	1.000	1835	tags=20%, list=10%, signal=22%
207	NCI_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		26	0.48	0.92	0.583	0.911	1.000	2304	tags=19%, list=12%, signal=22%
208	INOH_T CELL RECEPTOR SIGNALING PATHWAY		51	0.42	0.92	0.583	0.907	1.000	1955	tags=25%, list=11%, signal=28%
209	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE)		185	0.36	0.92	0.655	0.903	1.000	539	tags=4%, list=3%, signal=4%
210	BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK)		18	0.51	0.92	0.553	0.900	1.000	349	tags=11%, list=2%, signal=11%
211	INOH_INTEGRIN SIGNALING PATHWAY		92	0.39	0.92	0.631	0.907	1.000	2042	tags=14%, list=11%, signal=16%
212	NCI_FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS		37	0.44	0.92	0.563	0.902	1.000	16	tags=3%, list=0%, signal=3%
213	BIOCARTA_RAS SIGNALING PATHWAY		19	0.49	0.91	0.583	0.907	1.000	825	tags=16%, list=4%, signal=17%
214	BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION		28	0.45	0.91	0.600	0.910	1.000	825	tags=14%, list=4%, signal=15%
215	NCI_A4B1 AND A4B7 INTEGRIN SIGNALING		25	0.47	0.91	0.590	0.907	1.000	1442	tags=20%, list=8%, signal=22%
216	NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7		21	0.49	0.91	0.598	0.903	1.000	297	tags=10%, list=2%, signal=10%
217	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION		10	0.56	0.91	0.635	0.906	1.000	1094	tags=20%, list=6%, signal=21%
218	NCI_IGF1 PATHWAY		124	0.37	0.91	0.659	0.904	1.000	1850	tags=15%, list=10%, signal=16%
219	INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL)		189	0.35	0.91	0.739	0.903	1.000	423	tags=3%, list=2%, signal=3%
220	REACTOME_ATP_FORMATION		15	0.51	0.91	0.625	0.902	1.000	1894	tags=40%, list=10%, signal=44%
221	BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY		17	0.50	0.90	0.626	0.907	1.000	876	tags=18%, list=5%, signal=19%
222	REACTOME_METABOLISM_OF_AMINO_ACIDS		106	0.37	0.90	0.721	0.909	1.000	2607	tags=25%, list=14%, signal=28%
223	NETPATH_FLK2_FLT3		16	0.50	0.90	0.625	0.906	1.000	940	tags=13%, list=5%, signal=13%
224	NCI_REGULATION OF P38-ALPHA AND P38-BETA		142	0.35	0.90	0.727	0.907	1.000	2111	tags=16%, list=11%, signal=18%
225	NCI_EPHA2 FORWARD SIGNALING		17	0.50	0.89	0.632	0.913	1.000	18	tags=6%, list=0%, signal=6%
226	NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING		266	0.34	0.89	0.791	0.910	1.000	2349	tags=15%, list=13%, signal=17%
227	INOH_NEGATIVE FEEDBACK REGULATION OF TGF BETA SUPERFAMILY SIGNALING PATHWAY BY R-SMAD DAGRADATION		40	0.42	0.89	0.648	0.907	1.000	1308	tags=20%, list=7%, signal=21%
228	NCI_FGF SIGNALING PATHWAY		43	0.42	0.89	0.655	0.911	1.000	1082	tags=12%, list=6%, signal=12%
229	NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS		118	0.36	0.89	0.713	0.912	1.000	2111	tags=20%, list=11%, signal=23%
230	INOH_SNON DEGRADATION SIGNALING		25	0.46	0.88	0.638	0.913	1.000	1308	tags=24%, list=7%, signal=26%
231	HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS		33	0.44	0.88	0.667	0.910	1.000	1727	tags=27%, list=9%, signal=30%
232	NCI_IL27-MEDIATED SIGNALING EVENTS		26	0.46	0.88	0.650	0.916	1.000	3736	tags=35%, list=20%, signal=43%
233	CELLMAP_ALPHA6BETA4INTEGRIN		48	0.40	0.88	0.654	0.914	1.000	1030	tags=10%, list=6%, signal=11%
234	NCI_P38 MAPK SIGNALING PATHWAY		162	0.34	0.87	0.842	0.935	1.000	2111	tags=17%, list=11%, signal=19%
235	REACTOME_PLATELET_DEGRANULATION_		42	0.40	0.86	0.677	0.936	1.000	1861	tags=12%, list=10%, signal=13%
236	BIOCARTA_TPO SIGNALING PATHWAY		22	0.46	0.86	0.688	0.938	1.000	831	tags=14%, list=4%, signal=14%
237	INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING		105	0.35	0.86	0.783	0.937	1.000	539	tags=6%, list=3%, signal=6%
238	CELLMAP_NOTCH		45	0.40	0.86	0.689	0.935	1.000	1142	tags=16%, list=6%, signal=17%
239	HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION		30	0.44	0.86	0.674	0.935	1.000	2418	tags=37%, list=13%, signal=42%
240	NCI_ARF1 PATHWAY		13	0.50	0.86	0.667	0.932	1.000	1850	tags=46%, list=10%, signal=51%
241	BIOCARTA_VISUAL SIGNAL TRANSDUCTION		13	0.50	0.86	0.666	0.932	1.000	423	tags=8%, list=2%, signal=8%
242	REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES		64	0.38	0.85	0.726	0.931	1.000	2452	tags=20%, list=13%, signal=23%
243	REACTOME_PURINE_METABOLISM		39	0.41	0.85	0.698	0.932	1.000	1894	tags=26%, list=10%, signal=28%
244	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__		44	0.39	0.85	0.727	0.937	1.000	1861	tags=11%, list=10%, signal=13%
245	REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM		12	0.51	0.85	0.709	0.939	1.000	177	tags=8%, list=1%, signal=8%
246	REACTOME_CELL_JUNCTION_ORGANIZATION		23	0.44	0.84	0.678	0.942	1.000	212	tags=9%, list=1%, signal=9%
247	REACTOME_PAUSING_AND_RECOVERY_OF_HIV_1_ELONGATION		20	0.44	0.84	0.689	0.950	1.000	3450	tags=60%, list=19%, signal=74%
248	HUMANCYC_RESPIRATION (ANAEROBIC)		16	0.47	0.84	0.686	0.949	1.000	158	tags=13%, list=1%, signal=13%
249	NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA		56	0.37	0.83	0.762	0.948	1.000	963	tags=16%, list=5%, signal=17%
250	NETPATH_THROMBOPOIETIN		40	0.40	0.83	0.747	0.946	1.000	940	tags=15%, list=5%, signal=16%
251	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)		26	0.43	0.83	0.720	0.946	1.000	1955	tags=31%, list=11%, signal=34%
252	REACTOME_PAUSING_AND_RECOVERY_OF_TAT_MEDIATED_HIV_1_ELONGATION		19	0.44	0.83	0.700	0.943	1.000	3450	tags=63%, list=19%, signal=77%
253	HUMANCYC_COLANIC ACID BUILDING BLOCKS BIOSYNTHESIS		10	0.51	0.83	0.701	0.942	1.000	933	tags=20%, list=5%, signal=21%
254	REACTOME_CAP_DEPENDENT_TRANSLATION_INITIATION		58	0.38	0.83	0.766	0.939	1.000	174	tags=3%, list=1%, signal=3%
255	REACTOME_HIV_1_ELONGATION_ARREST_AND_RECOVERY		20	0.44	0.83	0.727	0.936	1.000	3450	tags=60%, list=19%, signal=74%
256	NCI_IL4-MEDIATED SIGNALING EVENTS		58	0.37	0.83	0.787	0.934	1.000	991	tags=14%, list=5%, signal=15%
257	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION		58	0.38	0.83	0.764	0.934	1.000	174	tags=3%, list=1%, signal=3%
258	BIOCARTA_TGF BETA SIGNALING PATHWAY		19	0.45	0.82	0.732	0.938	1.000	1030	tags=16%, list=6%, signal=17%
259	REACTOME_ELONGATION_ARREST_AND_RECOVERY		20	0.44	0.82	0.736	0.939	1.000	3450	tags=60%, list=19%, signal=74%
260	REACTOME_PAUSING_AND_RECOVERY_OF_ELONGATION		20	0.44	0.82	0.743	0.936	1.000	3450	tags=60%, list=19%, signal=74%
261	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		22	0.43	0.81	0.726	0.943	1.000	2567	tags=32%, list=14%, signal=37%
262	HUMANCYC_GLUTATHIONE-MEDIATED DETOXIFICATION		16	0.45	0.81	0.721	0.942	1.000	1785	tags=31%, list=10%, signal=35%
263	NETPATH_GDNF		29	0.41	0.81	0.753	0.940	1.000	940	tags=10%, list=5%, signal=11%
264	REACTOME_TAT_MEDIATED_HIV_1_ELONGATION_ARREST_AND_RECOVERY_		19	0.44	0.81	0.725	0.943	1.000	3450	tags=63%, list=19%, signal=77%
265	NCI_ATYPICAL NF-KAPPAB PATHWAY		14	0.47	0.81	0.740	0.944	1.000	3063	tags=36%, list=16%, signal=43%
266	BIOCARTA_CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) AND BETA 2 ADRENERGIC RECEPTOR (B2AR) PATHWAY		17	0.45	0.80	0.747	0.947	1.000	452	tags=18%, list=2%, signal=18%
267	REACTOME_MEMBRANE_TRAFFICKING		26	0.41	0.79	0.769	0.962	1.000	2170	tags=35%, list=12%, signal=39%
268	NCI_NONCANONICAL WNT SIGNALING PATHWAY		18	0.44	0.79	0.765	0.959	1.000	1647	tags=11%, list=9%, signal=12%
269	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT		57	0.36	0.79	0.858	0.956	1.000	2452	tags=19%, list=13%, signal=22%
270	REACTOME_TRANSLATION		63	0.35	0.79	0.859	0.952	1.000	174	tags=3%, list=1%, signal=3%
271	BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF)		15	0.44	0.79	0.768	0.950	1.000	825	tags=13%, list=4%, signal=14%
272	NCI_FOXA TRANSCRIPTION FACTOR NETWORKS		65	0.35	0.79	0.866	0.951	1.000	16	tags=2%, list=0%, signal=2%
273	BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES		15	0.45	0.79	0.741	0.947	1.000	825	tags=13%, list=4%, signal=14%
274	NETPATH_IL-7		16	0.44	0.79	0.758	0.945	1.000	875	tags=19%, list=5%, signal=20%
275	REACTOME_METABOLISM_OF_PROTEINS		98	0.33	0.79	0.921	0.943	1.000	2655	tags=18%, list=14%, signal=21%
276	NCI_FOXM1 TRANSCRIPTION FACTOR NETWORK		34	0.38	0.79	0.840	0.940	1.000	1583	tags=24%, list=9%, signal=26%
277	REACTOME_PI3K_AKT_SIGNALLING		12	0.47	0.78	0.750	0.948	1.000	18	tags=8%, list=0%, signal=8%
278	NETPATH_CD40		30	0.39	0.78	0.794	0.950	1.000	1565	tags=23%, list=8%, signal=25%
279	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS		18	0.43	0.78	0.774	0.950	1.000	840	tags=22%, list=5%, signal=23%
280	BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY		20	0.41	0.77	0.806	0.952	1.000	840	tags=15%, list=5%, signal=16%
281	NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY		33	0.38	0.77	0.822	0.949	1.000	2111	tags=21%, list=11%, signal=24%
282	INOH_ERK CASCADE		12	0.46	0.77	0.781	0.949	1.000	1272	tags=25%, list=7%, signal=27%
283	REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS		18	0.43	0.77	0.799	0.949	1.000	840	tags=22%, list=5%, signal=23%
284	REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE		15	0.43	0.76	0.803	0.952	1.000	1312	tags=13%, list=7%, signal=14%
285	NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA		46	0.35	0.76	0.889	0.962	1.000	2945	tags=22%, list=16%, signal=26%
286	REACTOME_TCR_SIGNALING		32	0.37	0.75	0.838	0.961	1.000	699	tags=9%, list=4%, signal=10%
287	REACTOME_COMMON_PATHWAY		11	0.46	0.75	0.798	0.959	1.000	1835	tags=9%, list=10%, signal=10%
288	NETPATH_EPO		39	0.36	0.75	0.901	0.959	1.000	1684	tags=18%, list=9%, signal=20%
289	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	0.43	0.75	0.809	0.961	1.000	831	tags=15%, list=4%, signal=16%
290	BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION		16	0.42	0.74	0.828	0.962	1.000	1835	tags=25%, list=10%, signal=28%
291	BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS		17	0.41	0.74	0.847	0.970	1.000	1962	tags=24%, list=11%, signal=26%
292	NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT)		48	0.33	0.73	0.933	0.975	1.000	1410	tags=13%, list=8%, signal=13%
293	BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS		22	0.39	0.73	0.886	0.974	1.000	1453	tags=18%, list=8%, signal=20%
294	HUMANCYC_FATTY ACID BETA-OXIDATION I		16	0.41	0.73	0.855	0.973	1.000	1864	tags=19%, list=10%, signal=21%
295	REACTOME_CITRIC_ACID_CYCLE__TCA_CYCLE_		12	0.43	0.72	0.837	0.978	1.000	951	tags=17%, list=5%, signal=18%
296	BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS		25	0.37	0.72	0.871	0.977	1.000	840	tags=16%, list=5%, signal=17%
297	INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS)		11	0.42	0.71	0.846	0.985	1.000	1272	tags=27%, list=7%, signal=29%
298	BIOCARTA_REGULATION OF PGC-1A		18	0.39	0.70	0.890	0.986	1.000	2870	tags=33%, list=15%, signal=39%
299	REACTOME_PURINE_BIOSYNTHESIS		24	0.36	0.70	0.927	0.988	1.000	1894	tags=29%, list=10%, signal=32%
300	BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS		19	0.38	0.70	0.891	0.985	1.000	1357	tags=16%, list=7%, signal=17%
301	BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY		16	0.39	0.70	0.869	0.983	1.000	914	tags=13%, list=5%, signal=13%
302	NETPATH_IL9		11	0.42	0.69	0.864	0.981	1.000	355	tags=9%, list=2%, signal=9%
303	BIOCARTA_GRANZYME A MEDIATED APOPTOSIS PATHWAY		12	0.40	0.69	0.877	0.983	1.000	1479	tags=17%, list=8%, signal=18%
304	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II		31	0.35	0.69	0.933	0.979	1.000	2955	tags=32%, list=16%, signal=38%
305	BIOCARTA_PROTEASOME COMPLEX		22	0.36	0.68	0.919	0.983	1.000	1230	tags=9%, list=7%, signal=10%
306	INOH_IKK-NF-KAPPAB CASCADE		12	0.41	0.68	0.879	0.980	1.000	3063	tags=42%, list=16%, signal=50%
307	REACTOME_SMOOTH_MUSCLE_CONTRACTION		12	0.40	0.68	0.885	0.980	1.000	1572	tags=17%, list=8%, signal=18%
308	BIOCARTA_PLATELET AMYLOID PRECURSOR PROTEIN PATHWAY		13	0.39	0.67	0.894	0.984	1.000	2042	tags=15%, list=11%, signal=17%
309	HUMANCYC_TCA CYCLE VARIATION III (EUKARYOTIC)		16	0.38	0.66	0.929	0.987	1.000	2402	tags=25%, list=13%, signal=29%
310	INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		10	0.40	0.66	0.895	0.987	1.000	307	tags=10%, list=2%, signal=10%
311	BIOCARTA_MECHANISM OF PROTEIN IMPORT INTO THE NUCLEUS		11	0.38	0.63	0.944	1.000	1.000	2224	tags=27%, list=12%, signal=31%
312	REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS		10	0.38	0.62	0.895	1.000	1.000	3537	tags=20%, list=19%, signal=25%
313	REACTOME_INTRINSIC_PATHWAY		16	0.35	0.62	0.961	0.998	1.000	1835	tags=13%, list=10%, signal=14%
314	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES		13	0.36	0.61	0.945	0.997	1.000	1240	tags=8%, list=7%, signal=8%
315	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE		13	0.35	0.61	0.959	0.995	1.000	3093	tags=31%, list=17%, signal=37%
316	REACTOME_FORMATION_OF_FIBRIN_CLOT__CLOTTING_CASCADE_		28	0.30	0.60	0.986	0.994	1.000	1835	tags=7%, list=10%, signal=8%
317	NCI_LPA4-MEDIATED SIGNALING EVENTS		12	0.36	0.59	0.948	0.994	1.000	1442	tags=8%, list=8%, signal=9%
318	INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING		36	0.29	0.59	0.996	0.991	1.000	423	tags=3%, list=2%, signal=3%
319	REACTOME_EGFR_DOWNREGULATION		10	0.34	0.55	0.974	0.997	1.000	4127	tags=40%, list=22%, signal=51%
320	BIOCARTA_FIBRINOLYSIS PATHWAY		12	0.30	0.51	0.992	0.999	1.000	1835	tags=8%, list=10%, signal=9%
321	BIOCARTA_CARDIAC PROTECTION AGAINST ROS		11	0.26	0.42	0.994	0.999	1.000	4035	tags=18%, list=22%, signal=23%