Details for gene set REACTOME_REGULATION_OF_BETA_CELL

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	truncNotch
GeneSet	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT
Enrichment Score (ES)	0.94785655
Normalized Enrichment Score (NES)	1.6944766
Nominal p-value	0.0
FDR q-value	0.09854008
FWER p-Value	0.119

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NOTCH1	3390114	66	2.087	0.4774	Yes
2	HES1	4810280	69	2.042	0.9479	Yes
3	NEUROD1	3060619	4321	0.047	0.7301	No
4	IAPP	4230040	4451	0.043	0.7332	No
5	SLC2A2	5130537 5720722 6770079	4575	0.040	0.7358	No
6	FOXA3	2680121	6057	0.018	0.6604	No
7	PTF1A	6450377	6096	0.018	0.6625	No
8	FGF10	730458 840706	6998	0.012	0.6168	No
9	NKX6-1	6040731	7598	0.009	0.5866	No
10	PDX1	6660647	8499	0.006	0.5396	No
11	INSM1	3450671	8929	0.005	0.5176	No
12	NKX2-2	4150731	9259	0.004	0.5007	No
13	ONECUT3	5720487 6100037	9739	0.002	0.4755	No
14	PAX4	6620619	9954	0.002	0.4644	No
15	AKT1	5290746	11232	-0.001	0.3961	No
16	HNF4G	5720451	11993	-0.004	0.3561	No

Fig 3: REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT: Random ES distribution
Gene set null distribution of ES for REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT