Table: Gene sets enriched in phenotype truncNotch (10 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	HUMANCYC_GLUCONEOGENESIS	Details ...	17	0.87	1.76	0.000	0.045	0.078	1055	tags=41%, list=6%, signal=44%
2	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Details ...	16	0.86	1.72	0.002	0.050	0.162	129	tags=13%, list=1%, signal=13%
3	HUMANCYC_GLYCOLYSIS III	Details ...	21	0.78	1.64	0.002	0.179	0.617	1055	tags=43%, list=6%, signal=45%
4	HUMANCYC_GLYCOLYSIS I	Details ...	20	0.78	1.61	0.002	0.220	0.784	1055	tags=45%, list=6%, signal=48%
5	HUMANCYC_SERINE-ISOCITRATE LYASE PATHWAY	Details ...	16	0.79	1.58	0.008	0.288	0.919	1499	tags=50%, list=8%, signal=54%
6	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION	Details ...	22	0.75	1.58	0.013	0.252	0.923	1110	tags=45%, list=6%, signal=48%
7	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS AND ENTNER-DOUDOROFF	Details ...	22	0.73	1.56	0.009	0.291	0.971	1055	tags=41%, list=6%, signal=43%
8	HUMANCYC_GLYCOLYSIS V	Details ...	18	0.77	1.54	0.013	0.342	0.997	1055	tags=44%, list=6%, signal=47%
9	REACTOME_STRIATED_MUSCLE_CONTRACTION	Details ...	14	0.79	1.52	0.016	0.389	0.999	1456	tags=29%, list=8%, signal=31%
10	BIOCARTA_IL 2 SIGNALING PATHWAY	Details ...	14	0.77	1.51	0.020	0.376	0.999	309	tags=36%, list=2%, signal=36%
11	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I	Details ...	10	0.83	1.47	0.019	0.606	1.000	1726	tags=50%, list=9%, signal=55%
12	NCI_ALPHA-SYNUCLEIN SIGNALING	Details ...	32	0.64	1.46	0.028	0.581	1.000	1927	tags=28%, list=10%, signal=31%
13	BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY	Details ...	11	0.80	1.44	0.037	0.646	1.000	1168	tags=36%, list=6%, signal=39%
14	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES	Details ...	11	0.79	1.43	0.037	0.656	1.000	1525	tags=55%, list=8%, signal=59%
15	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS	Details ...	19	0.69	1.43	0.043	0.629	1.000	3205	tags=42%, list=17%, signal=51%
16	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)	Details ...	16	0.72	1.43	0.066	0.605	1.000	3029	tags=31%, list=16%, signal=37%
17	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)	Details ...	16	0.72	1.43	0.049	0.573	1.000	3029	tags=31%, list=16%, signal=37%
18	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)	Details ...	17	0.71	1.43	0.069	0.549	1.000	3029	tags=29%, list=16%, signal=35%
19	REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS	Details ...	19	0.69	1.43	0.067	0.529	1.000	3205	tags=42%, list=17%, signal=51%
20	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	Details ...	12	0.76	1.41	0.047	0.569	1.000	2485	tags=17%, list=13%, signal=19%
21	INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5)		10	0.79	1.41	0.058	0.547	1.000	210	tags=10%, list=1%, signal=10%
22	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		16	0.72	1.41	0.055	0.537	1.000	3029	tags=31%, list=16%, signal=37%
23	REACTOME_PHASE_II_CONJUGATION		17	0.68	1.39	0.067	0.582	1.000	1233	tags=18%, list=7%, signal=19%
24	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III		30	0.62	1.39	0.043	0.558	1.000	1895	tags=47%, list=10%, signal=52%
25	REACTOME_GLUCONEOGENESIS		11	0.76	1.39	0.071	0.564	1.000	1055	tags=45%, list=6%, signal=48%
26	NCI_SIGNALING EVENTS MEDIATED BY PTP1B		46	0.57	1.38	0.044	0.560	1.000	2337	tags=24%, list=13%, signal=27%
27	NCI_VISUAL SIGNAL TRANSDUCTION: CONES		18	0.68	1.38	0.090	0.580	1.000	50	tags=6%, list=0%, signal=6%
28	REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_		93	0.50	1.36	0.024	0.656	1.000	3095	tags=14%, list=17%, signal=17%
29	BIOCARTA_CLASSICAL COMPLEMENT PATHWAY		10	0.76	1.35	0.106	0.648	1.000	1806	tags=20%, list=10%, signal=22%
30	REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS		12	0.72	1.35	0.104	0.661	1.000	59	tags=8%, list=0%, signal=8%
31	INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER		30	0.59	1.34	0.079	0.649	1.000	3139	tags=40%, list=17%, signal=48%
32	HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS		11	0.74	1.34	0.099	0.636	1.000	1726	tags=45%, list=9%, signal=50%
33	HUMANCYC_ENTNER-DOUDOROFF PATHWAY II (NON-PHOSPHORYLATIVE)		12	0.72	1.34	0.112	0.632	1.000	1833	tags=33%, list=10%, signal=37%
34	NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS		13	0.71	1.33	0.118	0.659	1.000	811	tags=15%, list=4%, signal=16%
35	REACTOME_EXOCYTOSIS_OF_ALPHA_GRANULE_		40	0.56	1.33	0.067	0.650	1.000	1928	tags=13%, list=10%, signal=14%
36	BIOCARTA_EPO SIGNALING PATHWAY		11	0.74	1.32	0.131	0.641	1.000	340	tags=27%, list=2%, signal=28%
37	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT		10	0.74	1.32	0.096	0.625	1.000	1806	tags=20%, list=10%, signal=22%
38	BIOCARTA_DOWNREGULATED OF MTA-3 IN ER-NEGATIVE BREAST TUMORS		18	0.67	1.32	0.113	0.614	1.000	1535	tags=33%, list=8%, signal=36%
39	INOH_JAK DEGRADATION SIGNALING		24	0.61	1.32	0.128	0.615	1.000	3139	tags=46%, list=17%, signal=55%
40	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING)		30	0.59	1.32	0.118	0.612	1.000	3139	tags=40%, list=17%, signal=48%
41	REACTOME_PHASE_1_FUNCTIONALIZATION		10	0.75	1.31	0.123	0.607	1.000	546	tags=20%, list=3%, signal=21%
42	REACTOME_COMPLEMENT_CASCADE		14	0.70	1.31	0.129	0.594	1.000	1806	tags=14%, list=10%, signal=16%
43	REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR		10	0.75	1.31	0.128	0.580	1.000	1292	tags=20%, list=7%, signal=21%
44	INOH_NOTCH SECRETORY PATHWAY (MAMMAL)		22	0.62	1.31	0.101	0.584	1.000	610	tags=32%, list=3%, signal=33%
45	INOH_MAMMALIAN NOTCH SIGNALING PATHWAY		22	0.62	1.30	0.118	0.616	1.000	610	tags=32%, list=3%, signal=33%
46	INOH_CANONICAL NOTCH SIGNALING PATHWAY		26	0.59	1.30	0.117	0.609	1.000	383	tags=23%, list=2%, signal=24%
47	INOH_NOTCH SECRETORY PATHWAY		26	0.59	1.29	0.128	0.607	1.000	383	tags=23%, list=2%, signal=24%
48	REACTOME_BIOLOGICAL_OXIDATIONS		46	0.52	1.28	0.099	0.647	1.000	1233	tags=11%, list=7%, signal=12%
49	HUMANCYC_ISOLEUCINE DEGRADATION III		13	0.67	1.28	0.149	0.639	1.000	808	tags=31%, list=4%, signal=32%
50	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS		39	0.53	1.27	0.108	0.663	1.000	2435	tags=36%, list=13%, signal=41%
51	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)		26	0.58	1.26	0.148	0.673	1.000	3139	tags=42%, list=17%, signal=51%
52	BIOCARTA_IL 4 SIGNALING PATHWAY		11	0.69	1.26	0.198	0.683	1.000	449	tags=27%, list=2%, signal=28%
53	INOH_GENE EXPRESSION OF SOCS3 BY STAT DIMER		26	0.58	1.25	0.162	0.709	1.000	3139	tags=42%, list=17%, signal=51%
54	BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION		13	0.65	1.25	0.178	0.696	1.000	236	tags=23%, list=1%, signal=23%
55	HUMANCYC_FATTY ACID BETA-OXIDATION II (CORE PATHWAY)		16	0.63	1.25	0.197	0.695	1.000	3135	tags=38%, list=17%, signal=45%
56	BIOCARTA_IL 3 SIGNALING PATHWAY		11	0.69	1.24	0.214	0.698	1.000	340	tags=27%, list=2%, signal=28%
57	HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION		30	0.55	1.24	0.141	0.692	1.000	2886	tags=40%, list=16%, signal=47%
58	INOH_CYTOKINE RECEPTOR DEGRADATION SIGNALING		20	0.59	1.23	0.181	0.710	1.000	3139	tags=50%, list=17%, signal=60%
59	REACTOME_DIABETES_PATHWAYS		159	0.42	1.23	0.078	0.710	1.000	2968	tags=31%, list=16%, signal=37%
60	REACTOME_MUSCLE_CONTRACTION		25	0.56	1.22	0.183	0.723	1.000	1456	tags=20%, list=8%, signal=22%
61	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		14	0.63	1.21	0.217	0.743	1.000	1591	tags=29%, list=9%, signal=31%
62	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION		22	0.57	1.21	0.190	0.739	1.000	2459	tags=23%, list=13%, signal=26%
63	NETPATH_IL2		61	0.47	1.20	0.157	0.771	1.000	1591	tags=20%, list=9%, signal=21%
64	REACTOME_PLATELET_DEGRANULATION_		42	0.50	1.20	0.164	0.766	1.000	1928	tags=12%, list=10%, signal=13%
65	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS		10	0.65	1.20	0.235	0.770	1.000	1092	tags=10%, list=6%, signal=11%
66	REACTOME_ELECTRON_TRANSPORT_CHAIN		53	0.48	1.20	0.168	0.763	1.000	2886	tags=45%, list=16%, signal=53%
67	BIOCARTA_STRESS INDUCTION OF HSP REGULATION		14	0.62	1.19	0.224	0.766	1.000	926	tags=21%, list=5%, signal=23%
68	REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES		64	0.46	1.19	0.169	0.761	1.000	3497	tags=27%, list=19%, signal=33%
69	BIOCARTA_EICOSANOID METABOLISM		19	0.58	1.18	0.242	0.786	1.000	2765	tags=26%, list=15%, signal=31%
70	BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS		10	0.66	1.18	0.281	0.776	1.000	3890	tags=40%, list=21%, signal=51%
71	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL		25	0.54	1.17	0.236	0.806	1.000	2032	tags=36%, list=11%, signal=40%
72	HUMANCYC_SUPERPATHWAY OF CITRULLINE METABOLISM		11	0.64	1.17	0.283	0.810	1.000	2579	tags=36%, list=14%, signal=42%
73	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__		44	0.49	1.16	0.225	0.806	1.000	1928	tags=11%, list=10%, signal=13%
74	BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY		17	0.56	1.16	0.250	0.808	1.000	426	tags=18%, list=2%, signal=18%
75	INOH_TGF BETA RECEPTOR I DEGRADATION SIGNALING		25	0.54	1.16	0.233	0.807	1.000	3139	tags=36%, list=17%, signal=43%
76	BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING		32	0.51	1.16	0.251	0.799	1.000	1528	tags=22%, list=8%, signal=24%
77	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR__IGF__ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS__IGFBPS_		12	0.61	1.16	0.287	0.793	1.000	4093	tags=50%, list=22%, signal=64%
78	REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT		14	0.61	1.15	0.291	0.790	1.000	3876	tags=64%, list=21%, signal=81%
79	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II		22	0.55	1.15	0.291	0.788	1.000	1726	tags=27%, list=9%, signal=30%
80	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING		12	0.63	1.15	0.295	0.789	1.000	1531	tags=50%, list=8%, signal=54%
81	BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS		15	0.59	1.15	0.297	0.789	1.000	236	tags=20%, list=1%, signal=20%
82	REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION		90	0.42	1.13	0.197	0.835	1.000	2886	tags=38%, list=16%, signal=44%
83	BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY		19	0.55	1.13	0.286	0.827	1.000	340	tags=16%, list=2%, signal=16%
84	BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY		12	0.62	1.13	0.322	0.819	1.000	426	tags=25%, list=2%, signal=26%
85	REACTOME_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS		11	0.61	1.13	0.325	0.819	1.000	2459	tags=27%, list=13%, signal=31%
86	INOH_TGF BETA RECEPTOR COMPLEX DEGRADATION SIGNALING		29	0.50	1.13	0.255	0.809	1.000	3139	tags=34%, list=17%, signal=41%
87	NETPATH_CD40		30	0.50	1.13	0.295	0.805	1.000	1179	tags=23%, list=6%, signal=25%
88	NCI_AMB2 INTEGRIN SIGNALING		48	0.46	1.12	0.250	0.804	1.000	2372	tags=21%, list=13%, signal=24%
89	REACTOME_METABOLISM_OF_BILE_ACIDS_AND_BILE_SALTS		14	0.59	1.12	0.313	0.800	1.000	1092	tags=7%, list=6%, signal=8%
90	BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION		48	0.45	1.12	0.276	0.796	1.000	353	tags=19%, list=2%, signal=19%
91	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		27	0.51	1.12	0.284	0.790	1.000	348	tags=15%, list=2%, signal=15%
92	HUMANCYC_TRIACYLGLYCEROL DEGRADATION		12	0.61	1.12	0.320	0.782	1.000	3832	tags=25%, list=21%, signal=31%
93	NETPATH_TCR		105	0.41	1.12	0.208	0.791	1.000	1785	tags=23%, list=10%, signal=25%
94	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT		57	0.44	1.12	0.247	0.783	1.000	3497	tags=26%, list=19%, signal=32%
95	REACTOME_ATP_FORMATION		15	0.57	1.11	0.312	0.776	1.000	2502	tags=40%, list=13%, signal=46%
96	BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY		24	0.52	1.11	0.311	0.791	1.000	426	tags=17%, list=2%, signal=17%
97	REACTOME_REGULATION_OF_INSULIN_SECRETION		101	0.40	1.11	0.234	0.785	1.000	2886	tags=36%, list=16%, signal=42%
98	NCI_IL12 SIGNALING MEDIATED BY STAT4		28	0.49	1.11	0.290	0.778	1.000	2125	tags=29%, list=11%, signal=32%
99	HUMANCYC_COLANIC ACID BUILDING BLOCKS BIOSYNTHESIS		10	0.63	1.11	0.375	0.770	1.000	762	tags=20%, list=4%, signal=21%
100	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		40	0.46	1.11	0.280	0.765	1.000	580	tags=13%, list=3%, signal=13%
101	REACTOME_METABOLISM_OF_NUCLEOTIDES		62	0.44	1.11	0.257	0.761	1.000	2582	tags=32%, list=14%, signal=37%
102	BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION		26	0.50	1.10	0.313	0.770	1.000	2455	tags=27%, list=13%, signal=31%
103	HUMANCYC_GLUTATHIONE-MEDIATED DETOXIFICATION		16	0.56	1.10	0.336	0.763	1.000	1233	tags=25%, list=7%, signal=27%
104	REACTOME_SIGNALING_BY_GPCR		141	0.39	1.10	0.221	0.765	1.000	3095	tags=13%, list=17%, signal=15%
105	NCI_THROMBOXANE A2 RECEPTOR SIGNALING		50	0.45	1.10	0.303	0.759	1.000	722	tags=18%, list=4%, signal=19%
106	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION		10	0.62	1.10	0.376	0.756	1.000	2032	tags=60%, list=11%, signal=67%
107	HUMANCYC_GLYCINE BETAINE DEGRADATION		10	0.63	1.09	0.368	0.750	1.000	2759	tags=30%, list=15%, signal=35%
108	INOH_B CELL RECEPTOR SIGNALING PATHWAY		68	0.42	1.09	0.277	0.754	1.000	1591	tags=22%, list=9%, signal=24%
109	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING		12	0.60	1.09	0.358	0.749	1.000	2458	tags=42%, list=13%, signal=48%
110	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		15	0.56	1.09	0.347	0.746	1.000	1615	tags=40%, list=9%, signal=44%
111	NCI_IL4-MEDIATED SIGNALING EVENTS		58	0.43	1.09	0.295	0.752	1.000	1757	tags=17%, list=9%, signal=19%
112	BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY		32	0.47	1.08	0.363	0.765	1.000	463	tags=16%, list=2%, signal=16%
113	REACTOME_SEMAPHORIN_INTERACTIONS		30	0.48	1.08	0.332	0.759	1.000	1531	tags=23%, list=8%, signal=25%
114	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS		53	0.43	1.08	0.308	0.753	1.000	3442	tags=15%, list=18%, signal=18%
115	CELLMAP_KITRECEPTOR		49	0.44	1.08	0.333	0.757	1.000	932	tags=14%, list=5%, signal=15%
116	NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5		29	0.48	1.07	0.363	0.758	1.000	1591	tags=17%, list=9%, signal=19%
117	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		15	0.56	1.07	0.376	0.756	1.000	1615	tags=40%, list=9%, signal=44%
118	REACTOME_METABOLISM_OF_AMINO_ACIDS		106	0.39	1.07	0.306	0.766	1.000	3242	tags=31%, list=17%, signal=37%
119	NCI_FGF SIGNALING PATHWAY		43	0.44	1.06	0.354	0.775	1.000	832	tags=12%, list=4%, signal=12%
120	REACTOME_METABOLISM_OF_CARBOHYDRATES		70	0.41	1.06	0.355	0.782	1.000	1055	tags=16%, list=6%, signal=17%
121	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM		109	0.38	1.05	0.350	0.810	1.000	2886	tags=33%, list=16%, signal=39%
122	NETPATH_IFN-ALPHA		43	0.43	1.04	0.385	0.825	1.000	1591	tags=26%, list=9%, signal=28%
123	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS		18	0.52	1.03	0.430	0.833	1.000	3242	tags=33%, list=17%, signal=40%
124	BIOCARTA_CASPASE CASCADE IN APOPTOSIS		21	0.49	1.03	0.385	0.835	1.000	2386	tags=33%, list=13%, signal=38%
125	NCI_IL27-MEDIATED SIGNALING EVENTS		26	0.47	1.03	0.414	0.837	1.000	1336	tags=15%, list=7%, signal=17%
126	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS		12	0.55	1.03	0.436	0.837	1.000	1615	tags=42%, list=9%, signal=46%
127	BIOCARTA_TPO SIGNALING PATHWAY		22	0.49	1.03	0.408	0.831	1.000	236	tags=14%, list=1%, signal=14%
128	BIOCARTA_IL 6 SIGNALING PATHWAY		13	0.55	1.02	0.458	0.844	1.000	183	tags=15%, list=1%, signal=16%
129	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		22	0.48	1.02	0.413	0.843	1.000	2125	tags=32%, list=11%, signal=36%
130	HUMANCYC_SALVAGE PATHWAYS OF PURINE AND PYRIMIDINE NUCLEOTIDES		19	0.50	1.01	0.437	0.852	1.000	3225	tags=37%, list=17%, signal=45%
131	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS		19	0.49	1.01	0.432	0.850	1.000	3144	tags=37%, list=17%, signal=44%
132	REACTOME_REGULATORY_RNA_PATHWAYS		10	0.56	1.01	0.458	0.858	1.000	3766	tags=50%, list=20%, signal=63%
133	REACTOME_INSULIN_SYNTHESIS_AND_SECRETION		66	0.39	1.00	0.431	0.859	1.000	2968	tags=26%, list=16%, signal=31%
134	BIOCARTA_INTRINSIC PROTHROMBIN ACTIVATION PATHWAY		22	0.47	1.00	0.467	0.875	1.000	3725	tags=18%, list=20%, signal=23%
135	BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY		20	0.47	1.00	0.473	0.869	1.000	426	tags=15%, list=2%, signal=15%
136	NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS		48	0.41	1.00	0.450	0.865	1.000	2032	tags=25%, list=11%, signal=28%
137	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		24	0.46	0.98	0.496	0.905	1.000	2882	tags=33%, list=15%, signal=39%
138	NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS		108	0.36	0.98	0.498	0.902	1.000	2125	tags=22%, list=11%, signal=25%
139	NETPATH_IL-7		16	0.50	0.98	0.495	0.902	1.000	216	tags=19%, list=1%, signal=19%
140	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION		47	0.39	0.98	0.474	0.896	1.000	2909	tags=26%, list=16%, signal=30%
141	NCI_ARF6 DOWNSTREAM PATHWAY		25	0.46	0.98	0.495	0.890	1.000	2533	tags=40%, list=14%, signal=46%
142	REACTOME_HEMOSTASIS		147	0.35	0.98	0.505	0.888	1.000	1928	tags=14%, list=10%, signal=15%
143	REACTOME_PEPTIDE_CHAIN_ELONGATION		45	0.40	0.97	0.490	0.889	1.000	2777	tags=24%, list=15%, signal=29%
144	REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS		44	0.40	0.97	0.500	0.893	1.000	2777	tags=25%, list=15%, signal=29%
145	NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES		43	0.40	0.97	0.512	0.894	1.000	1737	tags=16%, list=9%, signal=18%
146	NCI_PDGFR-BETA SIGNALING PATHWAY		51	0.39	0.97	0.520	0.889	1.000	2045	tags=16%, list=11%, signal=18%
147	REACTOME_GLUCOSE_METABOLISM		54	0.39	0.97	0.505	0.883	1.000	1055	tags=15%, list=6%, signal=16%
148	NETPATH_NGF		45	0.39	0.96	0.510	0.899	1.000	932	tags=18%, list=5%, signal=19%
149	NCI_EPO SIGNALING PATHWAY		32	0.42	0.96	0.502	0.896	1.000	736	tags=16%, list=4%, signal=16%
150	REACTOME_MEMBRANE_TRAFFICKING		26	0.43	0.96	0.524	0.900	1.000	1615	tags=35%, list=9%, signal=38%
151	NCI_IL12-MEDIATED SIGNALING EVENTS		104	0.35	0.95	0.533	0.896	1.000	2827	tags=24%, list=15%, signal=28%
152	NCI_S1P1 PATHWAY		64	0.37	0.95	0.559	0.893	1.000	876	tags=11%, list=5%, signal=11%
153	BIOCARTA_VISUAL SIGNAL TRANSDUCTION		13	0.50	0.95	0.524	0.894	1.000	50	tags=8%, list=0%, signal=8%
154	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	0.44	0.95	0.504	0.898	1.000	1737	tags=18%, list=9%, signal=20%
155	INOH_ERK CASCADE		12	0.51	0.95	0.569	0.897	1.000	576	tags=25%, list=3%, signal=26%
156	BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY		13	0.50	0.94	0.541	0.897	1.000	861	tags=23%, list=5%, signal=24%
157	REACTOME_PURINE_SALVAGE_REACTIONS		10	0.54	0.94	0.586	0.897	1.000	3049	tags=40%, list=16%, signal=48%
158	NCI_ARF1 PATHWAY		13	0.50	0.94	0.561	0.894	1.000	1684	tags=46%, list=9%, signal=51%
159	NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY		31	0.41	0.94	0.543	0.889	1.000	861	tags=19%, list=5%, signal=20%
160	BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING		34	0.41	0.94	0.546	0.885	1.000	439	tags=15%, list=2%, signal=15%
161	INOH_SNON DEGRADATION SIGNALING		25	0.44	0.94	0.549	0.886	1.000	3139	tags=40%, list=17%, signal=48%
162	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		196	0.32	0.94	0.666	0.889	1.000	2146	tags=16%, list=12%, signal=18%
163	HUMANCYC_SALVAGE PATHWAYS OF PYRIMIDINE RIBONUCLEOTIDES		12	0.51	0.93	0.573	0.885	1.000	3001	tags=25%, list=16%, signal=30%
164	HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS		33	0.41	0.93	0.546	0.881	1.000	2502	tags=30%, list=13%, signal=35%
165	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		68	0.36	0.93	0.591	0.889	1.000	2337	tags=18%, list=13%, signal=20%
166	REACTOME_PHASE_1___FUNCTIONALIZATION_OF_COMPOUNDS		29	0.42	0.93	0.567	0.896	1.000	546	tags=7%, list=3%, signal=7%
167	REACTOME_PAUSING_AND_RECOVERY_OF_ELONGATION		20	0.44	0.92	0.568	0.897	1.000	4042	tags=65%, list=22%, signal=83%
168	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	0.31	0.92	0.696	0.893	1.000	2531	tags=18%, list=14%, signal=21%
169	NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT)		48	0.38	0.92	0.601	0.888	1.000	715	tags=13%, list=4%, signal=13%
170	REACTOME_PYRIMIDINE_METABOLISM		17	0.47	0.92	0.606	0.884	1.000	1051	tags=29%, list=6%, signal=31%
171	NCI_EPHA FORWARD SIGNALING		30	0.41	0.92	0.583	0.879	1.000	2337	tags=17%, list=13%, signal=19%
172	REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS		15	0.47	0.92	0.563	0.876	1.000	1292	tags=20%, list=7%, signal=21%
173	REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM		12	0.49	0.92	0.573	0.875	1.000	46	tags=8%, list=0%, signal=8%
174	REACTOME_HIV_1_ELONGATION_ARREST_AND_RECOVERY		20	0.44	0.92	0.583	0.872	1.000	4042	tags=65%, list=22%, signal=83%
175	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I		90	0.34	0.92	0.649	0.871	1.000	2827	tags=33%, list=15%, signal=39%
176	REACTOME_TAT_MEDIATED_HIV_1_ELONGATION_ARREST_AND_RECOVERY_		19	0.44	0.91	0.589	0.883	1.000	4042	tags=68%, list=22%, signal=87%
177	BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES		15	0.47	0.91	0.592	0.882	1.000	236	tags=13%, list=1%, signal=13%
178	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		48	0.37	0.91	0.639	0.879	1.000	1652	tags=27%, list=9%, signal=30%
179	NETPATH_EPO		39	0.39	0.91	0.604	0.875	1.000	2827	tags=28%, list=15%, signal=33%
180	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION		10	0.52	0.91	0.607	0.870	1.000	560	tags=20%, list=3%, signal=21%
181	REACTOME_ELONGATION_ARREST_AND_RECOVERY		20	0.44	0.91	0.609	0.866	1.000	4042	tags=65%, list=22%, signal=83%
182	REACTOME_PAUSING_AND_RECOVERY_OF_HIV_1_ELONGATION		20	0.44	0.90	0.619	0.872	1.000	4042	tags=65%, list=22%, signal=83%
183	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		32	0.40	0.90	0.613	0.868	1.000	1652	tags=34%, list=9%, signal=38%
184	REACTOME_PAUSING_AND_RECOVERY_OF_TAT_MEDIATED_HIV_1_ELONGATION		19	0.44	0.90	0.615	0.864	1.000	4042	tags=68%, list=22%, signal=87%
185	BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES		28	0.41	0.90	0.602	0.865	1.000	1528	tags=18%, list=8%, signal=19%
186	NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA		46	0.36	0.90	0.631	0.865	1.000	1179	tags=11%, list=6%, signal=12%
187	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE)		185	0.31	0.90	0.754	0.861	1.000	2627	tags=9%, list=14%, signal=11%
188	BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE		14	0.47	0.89	0.613	0.865	1.000	2149	tags=29%, list=12%, signal=32%
189	NETPATH_THROMBOPOIETIN		40	0.38	0.89	0.652	0.865	1.000	1179	tags=15%, list=6%, signal=16%
190	REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE		15	0.46	0.89	0.637	0.864	1.000	2293	tags=20%, list=12%, signal=23%
191	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES		41	0.37	0.89	0.657	0.861	1.000	1292	tags=17%, list=7%, signal=18%
192	BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION		25	0.41	0.88	0.652	0.876	1.000	2827	tags=20%, list=15%, signal=24%
193	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	0.45	0.88	0.646	0.883	1.000	3499	tags=50%, list=19%, signal=62%
194	NCI_ATYPICAL NF-KAPPAB PATHWAY		14	0.46	0.87	0.644	0.886	1.000	3229	tags=36%, list=17%, signal=43%
195	REACTOME_EUKARYOTIC_TRANSLATION_TERMINATION		46	0.36	0.87	0.695	0.890	1.000	2777	tags=24%, list=15%, signal=28%
196	BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS		17	0.44	0.87	0.634	0.888	1.000	776	tags=18%, list=4%, signal=18%
197	REACTOME_PURINE_METABOLISM		39	0.37	0.87	0.703	0.888	1.000	3049	tags=33%, list=16%, signal=40%
198	REACTOME_SYNAPTIC_TRANSMISSION		42	0.36	0.87	0.680	0.885	1.000	1292	tags=17%, list=7%, signal=18%
199	REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING		20	0.42	0.86	0.657	0.891	1.000	1257	tags=20%, list=7%, signal=21%
200	BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF)		15	0.44	0.86	0.642	0.894	1.000	236	tags=13%, list=1%, signal=13%
201	REACTOME_VIRAL_MRNA_TRANSLATION		46	0.35	0.86	0.742	0.898	1.000	2777	tags=24%, list=15%, signal=28%
202	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		32	0.38	0.86	0.716	0.895	1.000	1737	tags=19%, list=9%, signal=21%
203	REACTOME_ORNITHINE_AND_PROLINE_METABOLISM		46	0.35	0.85	0.762	0.893	1.000	3189	tags=37%, list=17%, signal=44%
204	INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS)		11	0.46	0.85	0.691	0.896	1.000	576	tags=27%, list=3%, signal=28%
205	REACTOME_CHOLESTEROL_BIOSYNTHESIS		15	0.43	0.84	0.701	0.905	1.000	683	tags=33%, list=4%, signal=35%
206	BIOCARTA_CELL CYCLE: G2/M CHECKPOINT		19	0.42	0.84	0.707	0.904	1.000	1748	tags=21%, list=9%, signal=23%
207	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)		26	0.38	0.84	0.718	0.915	1.000	1591	tags=31%, list=9%, signal=34%
208	BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION		17	0.41	0.83	0.703	0.916	1.000	2125	tags=35%, list=11%, signal=40%
209	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP)		175	0.28	0.83	0.952	0.922	1.000	2517	tags=7%, list=14%, signal=8%
210	INOH_IKK-NF-KAPPAB CASCADE		12	0.45	0.83	0.692	0.922	1.000	3229	tags=42%, list=17%, signal=50%
211	NCI_FOXM1 TRANSCRIPTION FACTOR NETWORK		34	0.36	0.82	0.767	0.921	1.000	1065	tags=21%, list=6%, signal=22%
212	REACTOME_PURINE_BIOSYNTHESIS		24	0.38	0.82	0.728	0.918	1.000	2938	tags=33%, list=16%, signal=40%
213	BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION		16	0.41	0.82	0.715	0.914	1.000	2627	tags=31%, list=14%, signal=36%
214	BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME		10	0.46	0.82	0.737	0.917	1.000	1304	tags=30%, list=7%, signal=32%
215	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	0.38	0.82	0.753	0.914	1.000	2039	tags=36%, list=11%, signal=40%
216	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN)		175	0.28	0.82	0.947	0.912	1.000	2517	tags=7%, list=14%, signal=8%
217	BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY		32	0.36	0.82	0.785	0.911	1.000	463	tags=13%, list=2%, signal=13%
218	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	0.43	0.81	0.730	0.920	1.000	353	tags=15%, list=2%, signal=16%
219	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		28	0.36	0.81	0.788	0.919	1.000	2337	tags=32%, list=13%, signal=37%
220	NCI_IL23-MEDIATED SIGNALING EVENTS		65	0.32	0.81	0.866	0.915	1.000	2827	tags=22%, list=15%, signal=25%
221	BIOCARTA_ROLE OF BRCA1 BRCA2 AND ATR IN CANCER SUSCEPTIBILITY		21	0.38	0.80	0.772	0.919	1.000	1179	tags=14%, list=6%, signal=15%
222	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE DEOXYRIBONUCLEOTIDES		11	0.44	0.80	0.733	0.927	1.000	3172	tags=45%, list=17%, signal=55%
223	BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT		15	0.42	0.80	0.768	0.924	1.000	1336	tags=20%, list=7%, signal=22%
224	BIOCARTA_REGULATION OF PGC-1A		18	0.39	0.79	0.781	0.929	1.000	2039	tags=28%, list=11%, signal=31%
225	NCI_S1P4 PATHWAY		11	0.44	0.79	0.763	0.925	1.000	691	tags=18%, list=4%, signal=19%
226	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE)		197	0.27	0.79	0.994	0.924	1.000	2268	tags=7%, list=12%, signal=8%
227	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP)		179	0.27	0.79	0.989	0.924	1.000	2517	tags=7%, list=14%, signal=8%
228	BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS		21	0.37	0.78	0.799	0.925	1.000	1257	tags=19%, list=7%, signal=20%
229	HUMANCYC_SUPERPATHWAY OF GLYOXYLATE CYCLE		10	0.43	0.78	0.803	0.931	1.000	3411	tags=40%, list=18%, signal=49%
230	INOH_PLC BETA SIGNALING		18	0.38	0.77	0.790	0.933	1.000	1188	tags=22%, list=6%, signal=24%
231	REACTOME_CELL_JUNCTION_ORGANIZATION		23	0.36	0.77	0.850	0.931	1.000	2377	tags=22%, list=13%, signal=25%
232	BIOCARTA_HEMOGLOBINS CHAPERONE		10	0.43	0.77	0.770	0.933	1.000	3551	tags=50%, list=19%, signal=62%
233	BIOCARTA_SEGMENTATION CLOCK		22	0.36	0.77	0.842	0.933	1.000	1766	tags=14%, list=9%, signal=15%
234	INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR)		14	0.40	0.76	0.819	0.934	1.000	1188	tags=29%, list=6%, signal=30%
235	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE		13	0.41	0.76	0.778	0.932	1.000	2867	tags=31%, list=15%, signal=36%
236	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	0.38	0.76	0.828	0.932	1.000	1189	tags=24%, list=6%, signal=25%
237	NETPATH_FLK2_FLT3		16	0.38	0.75	0.840	0.944	1.000	932	tags=13%, list=5%, signal=13%
238	REACTOME_CITRIC_ACID_CYCLE__TCA_CYCLE_		12	0.40	0.73	0.824	0.958	1.000	2435	tags=25%, list=13%, signal=29%
239	REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE		17	0.37	0.73	0.851	0.954	1.000	2435	tags=29%, list=13%, signal=34%
240	BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN		14	0.38	0.73	0.857	0.953	1.000	2039	tags=29%, list=11%, signal=32%
241	HUMANCYC_TCA CYCLE VARIATION III (EUKARYOTIC)		16	0.36	0.72	0.874	0.958	1.000	2435	tags=25%, list=13%, signal=29%
242	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE		12	0.38	0.71	0.876	0.965	1.000	3242	tags=33%, list=17%, signal=40%
243	BIOCARTA_ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM		41	0.30	0.71	0.960	0.964	1.000	2455	tags=10%, list=13%, signal=11%
244	REACTOME_COMMON_PATHWAY		11	0.38	0.70	0.876	0.969	1.000	2455	tags=9%, list=13%, signal=10%
245	REACTOME_SMOOTH_MUSCLE_CONTRACTION		12	0.38	0.70	0.867	0.965	1.000	1448	tags=17%, list=8%, signal=18%
246	HUMANCYC_FATTY ACID BETA-OXIDATION I		16	0.35	0.70	0.917	0.963	1.000	808	tags=13%, list=4%, signal=13%
247	BIOCARTA_PLATELET AMYLOID PRECURSOR PROTEIN PATHWAY		13	0.37	0.69	0.896	0.963	1.000	4396	tags=31%, list=24%, signal=40%
248	HUMANCYC_PHOSPHOLIPASES		22	0.32	0.69	0.954	0.960	1.000	736	tags=5%, list=4%, signal=5%
249	REACTOME_CLASS_B_2__SECRETIN_FAMILY_RECEPTORS_		23	0.32	0.69	0.935	0.959	1.000	5118	tags=30%, list=27%, signal=42%
250	INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING		36	0.29	0.68	0.975	0.960	1.000	50	tags=3%, list=0%, signal=3%
251	REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS		10	0.37	0.67	0.917	0.964	1.000	4861	tags=30%, list=26%, signal=41%
252	REACTOME_EGFR_DOWNREGULATION		10	0.32	0.55	0.974	0.997	1.000	4005	tags=40%, list=22%, signal=51%
253	BIOCARTA_CARDIAC PROTECTION AGAINST ROS		11	0.26	0.47	0.998	0.998	1.000	4092	tags=18%, list=22%, signal=23%