Table: Gene sets enriched in phenotype ATM_plus (7 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	BIOCARTA_KERATINOCYTE DIFFERENTIATION	Details ...	50	-0.70	-1.93	0.000	0.013	0.012	2379	tags=44%, list=11%, signal=49%
2	NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS	Details ...	49	-0.67	-1.85	0.000	0.072	0.124	3038	tags=47%, list=14%, signal=54%
3	NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA	Details ...	34	-0.71	-1.81	0.000	0.098	0.246	2937	tags=50%, list=13%, signal=58%
4	NCI_ARF6 DOWNSTREAM PATHWAY	Details ...	27	-0.73	-1.80	0.000	0.081	0.270	2827	tags=44%, list=13%, signal=51%
5	NETPATH_TCR	Details ...	109	-0.57	-1.79	0.000	0.080	0.324	2575	tags=43%, list=12%, signal=49%
6	NCI_ARF1 PATHWAY	Details ...	14	-0.83	-1.78	0.005	0.084	0.383	1017	tags=43%, list=5%, signal=45%
7	BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS	Details ...	29	-0.71	-1.78	0.002	0.073	0.388	2379	tags=34%, list=11%, signal=39%
8	BIOCARTA_EICOSANOID METABOLISM	Details ...	20	-0.75	-1.77	0.002	0.067	0.402	1559	tags=35%, list=7%, signal=38%
9	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER	Details ...	13	-0.82	-1.76	0.002	0.083	0.522	3038	tags=77%, list=14%, signal=89%
10	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS	Details ...	19	-0.73	-1.70	0.002	0.159	0.793	2680	tags=53%, list=12%, signal=60%
11	CELLMAP_NOTCH	Details ...	48	-0.62	-1.69	0.007	0.169	0.833	3110	tags=38%, list=14%, signal=44%
12	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE	Details ...	11	-0.82	-1.69	0.000	0.160	0.843	2213	tags=45%, list=10%, signal=51%
13	BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION	Details ...	16	-0.77	-1.69	0.005	0.152	0.854	240	tags=13%, list=1%, signal=13%
14	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF	Details ...	17	-0.76	-1.69	0.008	0.150	0.868	2428	tags=41%, list=11%, signal=46%
15	BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL	Details ...	11	-0.81	-1.68	0.010	0.147	0.882	240	tags=18%, list=1%, signal=18%
16	NCI_CELLULAR ROLES OF ANTHRAX TOXIN	Details ...	15	-0.78	-1.66	0.007	0.185	0.944	2379	tags=40%, list=11%, signal=45%
17	REACTOME_PEPTIDE_CHAIN_ELONGATION	Details ...	41	-0.62	-1.65	0.007	0.195	0.957	241	tags=12%, list=1%, signal=12%
18	REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION	Details ...	27	-0.66	-1.63	0.015	0.224	0.977	538	tags=22%, list=2%, signal=23%
19	REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS	Details ...	40	-0.60	-1.63	0.009	0.217	0.979	56	tags=10%, list=0%, signal=10%
20	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION	Details ...	43	-0.60	-1.62	0.008	0.236	0.990	241	tags=12%, list=1%, signal=12%
21	BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF		51	-0.60	-1.62	0.005	0.228	0.990	3641	tags=49%, list=17%, signal=59%
22	NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS		118	-0.51	-1.62	0.002	0.221	0.992	2740	tags=35%, list=12%, signal=39%
23	INOH_CANONICAL NOTCH SIGNALING PATHWAY		25	-0.66	-1.61	0.017	0.233	0.997	3110	tags=36%, list=14%, signal=42%
24	NETPATH_IL6		60	-0.57	-1.61	0.002	0.224	0.997	3522	tags=37%, list=16%, signal=44%
25	REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS		45	-0.59	-1.60	0.012	0.236	0.999	387	tags=22%, list=2%, signal=23%
26	REACTOME__3___UTR_MEDIATED_TRANSLATIONAL_REGULATION		47	-0.58	-1.60	0.012	0.229	0.999	538	tags=13%, list=2%, signal=13%
27	REACTOME_ACTIVATION_OF_APC_C_AND_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS		46	-0.59	-1.60	0.004	0.222	0.999	735	tags=24%, list=3%, signal=25%
28	BIOCARTA_CASPASE CASCADE IN APOPTOSIS		21	-0.70	-1.60	0.009	0.215	0.999	2937	tags=52%, list=13%, signal=60%
29	BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION		16	-0.72	-1.60	0.009	0.209	0.999	2575	tags=44%, list=12%, signal=50%
30	NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT)		44	-0.59	-1.59	0.008	0.209	0.999	3549	tags=43%, list=16%, signal=51%
31	INOH_NOTCH SECRETORY PATHWAY		25	-0.66	-1.59	0.022	0.205	0.999	3110	tags=36%, list=14%, signal=42%
32	BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION		44	-0.59	-1.59	0.015	0.202	0.999	3457	tags=34%, list=16%, signal=40%
33	BIOCARTA_TNFR2 SIGNALING PATHWAY		12	-0.75	-1.59	0.023	0.201	0.999	2477	tags=58%, list=11%, signal=66%
34	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS__AND_SUBSEQUENT_BINDING_TO_43S		28	-0.64	-1.58	0.021	0.217	1.000	538	tags=21%, list=2%, signal=22%
35	REACTOME_CDC20_PHOSPHO_APC_C_MEDIATED_DEGRADATION_OF_CYCLIN_A		43	-0.57	-1.57	0.026	0.238	1.000	387	tags=21%, list=2%, signal=21%
36	INOH_ERK CASCADE		14	-0.73	-1.56	0.019	0.240	1.000	2379	tags=43%, list=11%, signal=48%
37	REACTOME_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION		47	-0.58	-1.56	0.003	0.235	1.000	538	tags=13%, list=2%, signal=13%
38	NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS		108	-0.50	-1.56	0.003	0.246	1.000	2864	tags=37%, list=13%, signal=42%
39	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		33	-0.61	-1.55	0.018	0.242	1.000	1806	tags=24%, list=8%, signal=26%
40	NCI_GLYPICAN PATHWAY		419	-0.44	-1.55	0.000	0.245	1.000	3035	tags=25%, list=14%, signal=29%
41	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES		13	-0.72	-1.55	0.051	0.251	1.000	4089	tags=46%, list=19%, signal=57%
42	NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES		43	-0.57	-1.55	0.005	0.246	1.000	1985	tags=23%, list=9%, signal=26%
43	NETPATH_IL2		58	-0.55	-1.54	0.012	0.249	1.000	2388	tags=34%, list=11%, signal=39%
44	BIOCARTA_MAPKINASE SIGNALING PATHWAY		53	-0.55	-1.54	0.016	0.252	1.000	2379	tags=32%, list=11%, signal=36%
45	NCI_TRAIL SIGNALING PATHWAY		276	-0.45	-1.54	0.000	0.253	1.000	3015	tags=28%, list=14%, signal=32%
46	NETPATH_IL-7		15	-0.70	-1.53	0.030	0.251	1.000	2723	tags=60%, list=12%, signal=68%
47	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION		53	-0.55	-1.53	0.010	0.251	1.000	538	tags=11%, list=2%, signal=12%
48	REACTOME_VIRAL_MRNA_TRANSLATION		42	-0.58	-1.53	0.023	0.256	1.000	56	tags=10%, list=0%, signal=10%
49	BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION		18	-0.68	-1.52	0.044	0.256	1.000	3653	tags=39%, list=17%, signal=47%
50	BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS		16	-0.70	-1.52	0.039	0.258	1.000	1102	tags=19%, list=5%, signal=20%
51	BIOCARTA_CERAMIDE SIGNALING PATHWAY		49	-0.54	-1.51	0.022	0.271	1.000	3601	tags=43%, list=16%, signal=51%
52	REACTOME_CAP_DEPENDENT_TRANSLATION_INITIATION		53	-0.55	-1.51	0.012	0.271	1.000	538	tags=11%, list=2%, signal=12%
53	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS		12	-0.73	-1.51	0.047	0.268	1.000	2070	tags=42%, list=9%, signal=46%
54	BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2		23	-0.64	-1.51	0.039	0.265	1.000	3264	tags=43%, list=15%, signal=51%
55	REACTOME_RIBOSOMAL_SCANNING_AND_START_CODON_RECOGNITION		27	-0.61	-1.51	0.034	0.266	1.000	538	tags=19%, list=2%, signal=19%
56	NCI_CASPASE CASCADE IN APOPTOSIS		45	-0.56	-1.50	0.025	0.273	1.000	2937	tags=40%, list=13%, signal=46%
57	REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1		40	-0.57	-1.50	0.017	0.269	1.000	387	tags=20%, list=2%, signal=20%
58	NCI_TNF RECEPTOR SIGNALING PATHWAY		247	-0.44	-1.50	0.000	0.267	1.000	3657	tags=33%, list=17%, signal=39%
59	INOH_SIGNALING WITHOUT WNT (MAMMAL)		25	-0.62	-1.50	0.046	0.263	1.000	3437	tags=40%, list=16%, signal=47%
60	BIOCARTA_PDGF SIGNALING PATHWAY		25	-0.62	-1.50	0.032	0.259	1.000	2379	tags=36%, list=11%, signal=40%
61	BIOCARTA_P38 MAPK SIGNALING PATHWAY		28	-0.60	-1.50	0.040	0.263	1.000	1328	tags=32%, list=6%, signal=34%
62	INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL)		20	-0.66	-1.49	0.043	0.268	1.000	3092	tags=45%, list=14%, signal=52%
63	NCI_IL6-MEDIATED SIGNALING EVENTS		43	-0.56	-1.48	0.014	0.284	1.000	3176	tags=37%, list=14%, signal=43%
64	CELLMAP_ANDROGENRECEPTOR		74	-0.51	-1.48	0.012	0.281	1.000	2271	tags=28%, list=10%, signal=32%
65	REACTOME_DEATH_RECEPTOR__SIGNALLING		12	-0.73	-1.48	0.059	0.279	1.000	2070	tags=42%, list=9%, signal=46%
66	NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY		33	-0.58	-1.48	0.037	0.277	1.000	3718	tags=36%, list=17%, signal=44%
67	REACTOME_EUKARYOTIC_TRANSLATION_TERMINATION		42	-0.56	-1.48	0.038	0.285	1.000	56	tags=10%, list=0%, signal=10%
68	REACTOME_TRANSLATION		58	-0.53	-1.47	0.023	0.287	1.000	538	tags=12%, list=2%, signal=12%
69	NETPATH_IL3		63	-0.51	-1.47	0.013	0.285	1.000	3751	tags=37%, list=17%, signal=44%
70	NCI_CLASS I PI3K SIGNALING EVENTS		217	-0.44	-1.47	0.003	0.281	1.000	2699	tags=24%, list=12%, signal=28%
71	NCI_FAS SIGNALING PATHWAY (CD95)		32	-0.58	-1.47	0.048	0.285	1.000	1925	tags=28%, list=9%, signal=31%
72	REACTOME_METABOLISM_OF_MRNA		21	-0.62	-1.47	0.047	0.283	1.000	3206	tags=43%, list=15%, signal=50%
73	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	-0.62	-1.47	0.043	0.281	1.000	688	tags=18%, list=3%, signal=19%
74	BIOCARTA_TPO SIGNALING PATHWAY		23	-0.61	-1.47	0.053	0.277	1.000	2379	tags=39%, list=11%, signal=44%
75	NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING		278	-0.43	-1.47	0.001	0.274	1.000	1985	tags=19%, list=9%, signal=20%
76	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY		21	-0.62	-1.47	0.043	0.273	1.000	3206	tags=43%, list=15%, signal=50%
77	REACTOME_VPU_MEDIATED_DEGRADATION_OF_CD4		36	-0.57	-1.46	0.050	0.275	1.000	387	tags=22%, list=2%, signal=23%
78	NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY		32	-0.57	-1.46	0.045	0.274	1.000	1644	tags=25%, list=7%, signal=27%
79	BIOCARTA_FAS SIGNALING PATHWAY (CD95)		19	-0.62	-1.46	0.041	0.275	1.000	1925	tags=32%, list=9%, signal=35%
80	REACTOME_DEADENYLATION_OF_MRNA		10	-0.71	-1.45	0.070	0.281	1.000	65	tags=20%, list=0%, signal=20%
81	BIOCARTA_TNFR1 SIGNALING PATHWAY		17	-0.65	-1.45	0.073	0.278	1.000	3641	tags=47%, list=17%, signal=56%
82	BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY		13	-0.68	-1.45	0.066	0.276	1.000	3636	tags=38%, list=17%, signal=46%
83	INOH_NOTCH SECRETORY PATHWAY (MAMMAL)		22	-0.62	-1.45	0.049	0.274	1.000	1984	tags=32%, list=9%, signal=35%
84	REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS		48	-0.53	-1.45	0.036	0.276	1.000	735	tags=23%, list=3%, signal=24%
85	NCI_GLYPICAN 1 NETWORK		384	-0.41	-1.45	0.000	0.274	1.000	2699	tags=22%, list=12%, signal=25%
86	REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT		48	-0.52	-1.45	0.040	0.276	1.000	538	tags=10%, list=2%, signal=11%
87	BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS		16	-0.65	-1.45	0.066	0.276	1.000	3636	tags=50%, list=17%, signal=60%
88	BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY		13	-0.68	-1.45	0.080	0.274	1.000	2379	tags=31%, list=11%, signal=34%
89	INOH_MAMMALIAN NOTCH SIGNALING PATHWAY		22	-0.62	-1.44	0.053	0.278	1.000	1984	tags=32%, list=9%, signal=35%
90	REACTOME_APOPTOTIC_EXECUTION__PHASE		31	-0.57	-1.44	0.055	0.282	1.000	1841	tags=19%, list=8%, signal=21%
91	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL)		29	-0.57	-1.44	0.040	0.282	1.000	3092	tags=31%, list=14%, signal=36%
92	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS		25	-0.59	-1.43	0.073	0.294	1.000	1841	tags=20%, list=8%, signal=22%
93	BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY		11	-0.68	-1.43	0.087	0.301	1.000	3653	tags=64%, list=17%, signal=76%
94	BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION		17	-0.63	-1.42	0.080	0.302	1.000	3481	tags=41%, list=16%, signal=49%
95	INOH_RAF ACTIVATION SIGNALING (THROUGH RASGRP)		10	-0.70	-1.42	0.093	0.307	1.000	2379	tags=40%, list=11%, signal=45%
96	NCI_IFN-GAMMA PATHWAY		334	-0.41	-1.42	0.003	0.304	1.000	2723	tags=23%, list=12%, signal=26%
97	NETPATH_THROMBOPOIETIN		40	-0.54	-1.42	0.055	0.309	1.000	3148	tags=40%, list=14%, signal=47%
98	INOH_T CELL RECEPTOR SIGNALING PATHWAY		52	-0.51	-1.41	0.049	0.311	1.000	2379	tags=27%, list=11%, signal=30%
99	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		18	-0.63	-1.41	0.084	0.309	1.000	2645	tags=33%, list=12%, signal=38%
100	NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES		80	-0.48	-1.41	0.028	0.308	1.000	2105	tags=21%, list=10%, signal=23%
101	BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS		27	-0.56	-1.41	0.060	0.314	1.000	2379	tags=37%, list=11%, signal=41%
102	REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION		36	-0.54	-1.41	0.045	0.311	1.000	387	tags=19%, list=2%, signal=20%
103	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS		14	-0.65	-1.41	0.092	0.309	1.000	3978	tags=57%, list=18%, signal=70%
104	REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G		38	-0.54	-1.41	0.068	0.309	1.000	604	tags=21%, list=3%, signal=22%
105	BIOCARTA_BCR SIGNALING PATHWAY		29	-0.57	-1.41	0.060	0.308	1.000	2379	tags=34%, list=11%, signal=39%
106	REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION1		35	-0.54	-1.41	0.057	0.305	1.000	387	tags=20%, list=2%, signal=20%
107	NCI_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		26	-0.58	-1.40	0.096	0.303	1.000	427	tags=19%, list=2%, signal=20%
108	INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR)		15	-0.63	-1.40	0.096	0.312	1.000	2379	tags=33%, list=11%, signal=37%
109	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		18	-0.62	-1.40	0.111	0.311	1.000	2407	tags=28%, list=11%, signal=31%
110	INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5)		10	-0.70	-1.39	0.114	0.317	1.000	3522	tags=40%, list=16%, signal=48%
111	REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1		36	-0.53	-1.39	0.049	0.317	1.000	387	tags=19%, list=2%, signal=20%
112	INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4		12	-0.66	-1.39	0.120	0.324	1.000	1340	tags=33%, list=6%, signal=35%
113	BIOCARTA_TNF/STRESS RELATED SIGNALING		23	-0.59	-1.39	0.075	0.321	1.000	3641	tags=48%, list=17%, signal=57%
114	NETPATH_BCR		121	-0.43	-1.39	0.021	0.319	1.000	2379	tags=25%, list=11%, signal=28%
115	REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D1		37	-0.53	-1.39	0.082	0.321	1.000	387	tags=19%, list=2%, signal=19%
116	REACTOME_REGULATION_OF_APOPTOSIS		37	-0.53	-1.39	0.082	0.320	1.000	387	tags=19%, list=2%, signal=19%
117	REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D		37	-0.53	-1.38	0.079	0.323	1.000	387	tags=19%, list=2%, signal=19%
118	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)		17	-0.62	-1.38	0.105	0.321	1.000	2407	tags=29%, list=11%, signal=33%
119	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		17	-0.62	-1.38	0.104	0.321	1.000	2407	tags=29%, list=11%, signal=33%
120	REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C		39	-0.52	-1.38	0.063	0.322	1.000	387	tags=18%, list=2%, signal=18%
121	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	-0.56	-1.38	0.088	0.320	1.000	2995	tags=40%, list=14%, signal=46%
122	INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I)		12	-0.66	-1.38	0.110	0.318	1.000	1340	tags=33%, list=6%, signal=35%
123	REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT		36	-0.53	-1.38	0.090	0.315	1.000	387	tags=19%, list=2%, signal=20%
124	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		44	-0.51	-1.38	0.072	0.313	1.000	2682	tags=36%, list=12%, signal=41%
125	REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_		38	-0.53	-1.38	0.061	0.315	1.000	387	tags=18%, list=2%, signal=19%
126	NCI_IL27-MEDIATED SIGNALING EVENTS		24	-0.58	-1.38	0.089	0.313	1.000	3176	tags=42%, list=14%, signal=49%
127	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING)		30	-0.54	-1.37	0.092	0.321	1.000	1076	tags=27%, list=5%, signal=28%
128	NETPATH_IL4		44	-0.51	-1.37	0.082	0.319	1.000	3522	tags=36%, list=16%, signal=43%
129	BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY		32	-0.54	-1.37	0.101	0.320	1.000	2932	tags=31%, list=13%, signal=36%
130	INOH_JNK CASCADE		16	-0.62	-1.36	0.114	0.325	1.000	1644	tags=31%, list=7%, signal=34%
131	BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME		10	-0.67	-1.36	0.130	0.323	1.000	5564	tags=80%, list=25%, signal=107%
132	REACTOME_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A		36	-0.53	-1.36	0.096	0.325	1.000	387	tags=19%, list=2%, signal=20%
133	INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER		30	-0.54	-1.36	0.087	0.326	1.000	1076	tags=27%, list=5%, signal=28%
134	BIOCARTA_EGF SIGNALING PATHWAY		19	-0.58	-1.36	0.115	0.323	1.000	1328	tags=26%, list=6%, signal=28%
135	BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR		36	-0.52	-1.36	0.084	0.321	1.000	2801	tags=31%, list=13%, signal=35%
136	REACTOME_REGULATION_OF_APC_C_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE		47	-0.49	-1.36	0.096	0.322	1.000	735	tags=21%, list=3%, signal=22%
137	REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX		40	-0.50	-1.36	0.096	0.326	1.000	387	tags=18%, list=2%, signal=18%
138	NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS		241	-0.40	-1.36	0.014	0.325	1.000	2011	tags=22%, list=9%, signal=23%
139	NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING		262	-0.39	-1.35	0.014	0.324	1.000	2178	tags=18%, list=10%, signal=20%
140	NCI_BCR SIGNALING PATHWAY		63	-0.47	-1.35	0.075	0.326	1.000	2379	tags=25%, list=11%, signal=28%
141	REACTOME_APOPTOSIS		96	-0.44	-1.35	0.041	0.324	1.000	2070	tags=20%, list=9%, signal=22%
142	NCI_BMP RECEPTOR SIGNALING		197	-0.41	-1.35	0.015	0.324	1.000	2379	tags=20%, list=11%, signal=23%
143	REACTOME_STABILIZATION_OF_P53		38	-0.51	-1.35	0.090	0.323	1.000	387	tags=18%, list=2%, signal=19%
144	REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE		36	-0.53	-1.35	0.077	0.321	1.000	387	tags=19%, list=2%, signal=20%
145	REACTOME_OPIOID_SIGNALLING		23	-0.57	-1.35	0.122	0.319	1.000	3636	tags=43%, list=17%, signal=52%
146	BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1		13	-0.64	-1.35	0.124	0.317	1.000	3653	tags=62%, list=17%, signal=74%
147	REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1		37	-0.51	-1.35	0.094	0.315	1.000	387	tags=19%, list=2%, signal=19%
148	NETPATH_EPO		37	-0.51	-1.35	0.098	0.313	1.000	3148	tags=43%, list=14%, signal=50%
149	REACTOME_SIGNALING_BY_WNT		38	-0.52	-1.35	0.085	0.318	1.000	387	tags=18%, list=2%, signal=19%
150	INOH_B CELL RECEPTOR SIGNALING PATHWAY		71	-0.47	-1.35	0.070	0.316	1.000	2723	tags=27%, list=12%, signal=30%
151	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		33	-0.52	-1.35	0.103	0.315	1.000	3457	tags=36%, list=16%, signal=43%
152	BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS		15	-0.63	-1.35	0.103	0.314	1.000	3991	tags=47%, list=18%, signal=57%
153	NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1		18	-0.60	-1.34	0.135	0.315	1.000	2159	tags=39%, list=10%, signal=43%
154	NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING		262	-0.39	-1.34	0.015	0.315	1.000	2178	tags=18%, list=10%, signal=20%
155	NCI_IL12 SIGNALING MEDIATED BY STAT4		27	-0.53	-1.34	0.101	0.317	1.000	3038	tags=44%, list=14%, signal=52%
156	NCI_TGF-BETA RECEPTOR SIGNALING		262	-0.39	-1.34	0.007	0.318	1.000	2178	tags=18%, list=10%, signal=20%
157	NCI_IL4-MEDIATED SIGNALING EVENTS		57	-0.47	-1.34	0.093	0.321	1.000	2932	tags=33%, list=13%, signal=38%
158	NCI_E-CADHERIN SIGNALING IN THE NASCENT ADHERENS JUNCTION		43	-0.49	-1.33	0.094	0.332	1.000	1822	tags=26%, list=8%, signal=28%
159	NCI_P38 MAPK SIGNALING PATHWAY		164	-0.41	-1.33	0.044	0.332	1.000	2675	tags=21%, list=12%, signal=24%
160	BIOCARTA_PROTEASOME COMPLEX		23	-0.55	-1.32	0.136	0.336	1.000	81	tags=17%, list=0%, signal=17%
161	REACTOME_CELL_JUNCTION_ORGANIZATION		25	-0.54	-1.32	0.120	0.336	1.000	4214	tags=48%, list=19%, signal=59%
162	INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL)		24	-0.55	-1.32	0.129	0.340	1.000	3092	tags=38%, list=14%, signal=44%
163	BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD		15	-0.60	-1.32	0.133	0.340	1.000	5564	tags=60%, list=25%, signal=80%
164	CELLMAP_TNF ALPHA/NF-KB		156	-0.41	-1.32	0.040	0.338	1.000	3641	tags=33%, list=17%, signal=39%
165	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		24	-0.53	-1.32	0.137	0.339	1.000	2575	tags=33%, list=12%, signal=38%
166	NCI_REGULATION OF P38-ALPHA AND P38-BETA		144	-0.41	-1.31	0.043	0.347	1.000	2105	tags=17%, list=10%, signal=19%
167	NCI_ENDOTHELINS		151	-0.41	-1.31	0.053	0.351	1.000	3238	tags=24%, list=15%, signal=28%
168	NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS		54	-0.48	-1.31	0.094	0.351	1.000	2379	tags=30%, list=11%, signal=33%
169	REACTOME_MEMBRANE_TRAFFICKING		24	-0.54	-1.31	0.124	0.350	1.000	4165	tags=38%, list=19%, signal=46%
170	BIOCARTA_IGF-1 SIGNALING PATHWAY		20	-0.57	-1.31	0.130	0.350	1.000	2379	tags=25%, list=11%, signal=28%
171	BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY		15	-0.61	-1.30	0.155	0.357	1.000	2937	tags=33%, list=13%, signal=38%
172	NCI_NONGENOTROPIC ANDROGEN SIGNALING		24	-0.54	-1.30	0.135	0.360	1.000	3636	tags=42%, list=17%, signal=50%
173	BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY		21	-0.56	-1.30	0.163	0.364	1.000	2990	tags=29%, list=14%, signal=33%
174	INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		17	-0.57	-1.30	0.162	0.364	1.000	4341	tags=41%, list=20%, signal=51%
175	REACTOME_G_PROTEIN_MEDIATED_EVENTS		12	-0.63	-1.30	0.159	0.363	1.000	3636	tags=58%, list=17%, signal=70%
176	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		49	-0.47	-1.29	0.114	0.364	1.000	2379	tags=27%, list=11%, signal=30%
177	NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS		157	-0.40	-1.29	0.061	0.366	1.000	1979	tags=22%, list=9%, signal=24%
178	INOH_SIGNALING WITHOUT WNT (CANONICAL)		29	-0.52	-1.29	0.134	0.364	1.000	3437	tags=34%, list=16%, signal=41%
179	NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK		35	-0.50	-1.28	0.131	0.379	1.000	2638	tags=26%, list=12%, signal=29%
180	INOH_GENE EXPRESSION OF SOCS3 BY STAT DIMER		26	-0.53	-1.28	0.157	0.382	1.000	1021	tags=23%, list=5%, signal=24%
181	NETPATH_IL9		10	-0.62	-1.28	0.191	0.383	1.000	2723	tags=40%, list=12%, signal=46%
182	NCI_INSULIN PATHWAY		120	-0.41	-1.28	0.082	0.382	1.000	1979	tags=21%, list=9%, signal=23%
183	NETPATH_FLK2_FLT3		16	-0.57	-1.28	0.186	0.381	1.000	3522	tags=44%, list=16%, signal=52%
184	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING)		26	-0.53	-1.28	0.152	0.381	1.000	1021	tags=23%, list=5%, signal=24%
185	REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING		21	-0.56	-1.28	0.159	0.381	1.000	3838	tags=38%, list=17%, signal=46%
186	REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6		36	-0.48	-1.27	0.159	0.386	1.000	387	tags=19%, list=2%, signal=20%
187	BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC		22	-0.53	-1.27	0.149	0.384	1.000	2932	tags=41%, list=13%, signal=47%
188	BIOCARTA_HYPOXIA-INDUCIBLE FACTOR IN THE CARDIVASCULAR SYSTEM		13	-0.60	-1.27	0.186	0.385	1.000	42	tags=8%, list=0%, signal=8%
189	REACTOME_ELONGATION_ARREST_AND_RECOVERY		23	-0.53	-1.27	0.173	0.385	1.000	724	tags=17%, list=3%, signal=18%
190	BIOCARTA_B CELL SURVIVAL PATHWAY		13	-0.61	-1.27	0.185	0.383	1.000	210	tags=15%, list=1%, signal=16%
191	BIOCARTA_REGULATION OF EIF-4E AND P70S6 KINASE		22	-0.53	-1.27	0.173	0.383	1.000	2379	tags=27%, list=11%, signal=31%
192	NCI_ARF6 TRAFFICKING EVENTS		120	-0.41	-1.27	0.098	0.383	1.000	1979	tags=21%, list=9%, signal=23%
193	INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE		36	-0.49	-1.27	0.153	0.383	1.000	1861	tags=25%, list=8%, signal=27%
194	NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING		93	-0.42	-1.27	0.105	0.382	1.000	3718	tags=31%, list=17%, signal=37%
195	BIOCARTA_IL 3 SIGNALING PATHWAY		11	-0.63	-1.26	0.206	0.382	1.000	3751	tags=55%, list=17%, signal=66%
196	NCI_ARF6 SIGNALING EVENTS		120	-0.41	-1.26	0.081	0.382	1.000	1979	tags=21%, list=9%, signal=23%
197	REACTOME_PAUSING_AND_RECOVERY_OF_ELONGATION		23	-0.53	-1.26	0.180	0.380	1.000	724	tags=17%, list=3%, signal=18%
198	BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS		23	-0.54	-1.26	0.180	0.385	1.000	4127	tags=48%, list=19%, signal=59%
199	NCI_NONCANONICAL WNT SIGNALING PATHWAY		18	-0.55	-1.26	0.173	0.387	1.000	958	tags=22%, list=4%, signal=23%
200	NCI_IL1-MEDIATED SIGNALING EVENTS		187	-0.39	-1.26	0.050	0.389	1.000	3729	tags=28%, list=17%, signal=33%
201	NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET)		149	-0.39	-1.25	0.067	0.390	1.000	1979	tags=22%, list=9%, signal=24%
202	NCI_IGF1 PATHWAY		132	-0.39	-1.25	0.081	0.389	1.000	3522	tags=28%, list=16%, signal=33%
203	NCI_ALPHA-SYNUCLEIN SIGNALING		31	-0.50	-1.25	0.166	0.387	1.000	3238	tags=26%, list=15%, signal=30%
204	BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB		12	-0.61	-1.25	0.218	0.390	1.000	3636	tags=42%, list=17%, signal=50%
205	REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX		47	-0.46	-1.25	0.149	0.390	1.000	726	tags=17%, list=3%, signal=18%
206	REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS		78	-0.42	-1.25	0.118	0.389	1.000	755	tags=15%, list=3%, signal=16%
207	NCI_A4B1 AND A4B7 INTEGRIN SIGNALING		25	-0.52	-1.25	0.197	0.388	1.000	5564	tags=64%, list=25%, signal=86%
208	REACTOME_M_G1_TRANSITION		47	-0.46	-1.25	0.169	0.386	1.000	726	tags=17%, list=3%, signal=18%
209	REACTOME_PAUSING_AND_RECOVERY_OF_HIV_1_ELONGATION		23	-0.53	-1.25	0.190	0.388	1.000	724	tags=17%, list=3%, signal=18%
210	BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY		19	-0.54	-1.25	0.204	0.386	1.000	3327	tags=26%, list=15%, signal=31%
211	BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY		35	-0.49	-1.25	0.155	0.388	1.000	2979	tags=31%, list=14%, signal=36%
212	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL)		33	-0.49	-1.25	0.151	0.387	1.000	1930	tags=21%, list=9%, signal=23%
213	REACTOME_INSULIN_SYNTHESIS_AND_SECRETION		63	-0.43	-1.25	0.121	0.386	1.000	56	tags=6%, list=0%, signal=6%
214	NCI_OSTEOPONTIN-MEDIATED EVENTS		29	-0.49	-1.25	0.171	0.384	1.000	2718	tags=38%, list=12%, signal=43%
215	NETPATH_IL5		32	-0.48	-1.24	0.167	0.383	1.000	2151	tags=28%, list=10%, signal=31%
216	NETPATH_CD40		29	-0.49	-1.24	0.166	0.383	1.000	2864	tags=45%, list=13%, signal=51%
217	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		41	-0.47	-1.24	0.154	0.385	1.000	3264	tags=34%, list=15%, signal=40%
218	BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY		16	-0.56	-1.24	0.209	0.387	1.000	895	tags=25%, list=4%, signal=26%
219	REACTOME_PLC_BETA_MEDIATED_EVENTS		10	-0.63	-1.23	0.230	0.397	1.000	3636	tags=70%, list=17%, signal=84%
220	NCI_IL12-MEDIATED SIGNALING EVENTS		101	-0.40	-1.23	0.113	0.397	1.000	3038	tags=32%, list=14%, signal=37%
221	REACTOME_SCF_SKP2__MEDIATED_DEGRADATION_OF_P27_P21		39	-0.46	-1.23	0.171	0.397	1.000	387	tags=18%, list=2%, signal=18%
222	BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES		28	-0.50	-1.23	0.203	0.403	1.000	2464	tags=29%, list=11%, signal=32%
223	REACTOME_HIV_1_ELONGATION_ARREST_AND_RECOVERY		23	-0.53	-1.23	0.194	0.403	1.000	724	tags=17%, list=3%, signal=18%
224	REACTOME_METABOLISM_OF_PROTEINS		93	-0.40	-1.23	0.124	0.404	1.000	538	tags=9%, list=2%, signal=9%
225	REACTOME_ORNITHINE_METABOLISM		43	-0.46	-1.22	0.156	0.411	1.000	387	tags=16%, list=2%, signal=17%
226	BIOCARTA_PTEN DEPENDENT CELL CYCLE ARREST AND APOPTOSIS		14	-0.57	-1.22	0.244	0.412	1.000	3457	tags=43%, list=16%, signal=51%
227	REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY		45	-0.44	-1.21	0.192	0.421	1.000	387	tags=16%, list=2%, signal=16%
228	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS		19	-0.51	-1.21	0.221	0.424	1.000	3991	tags=37%, list=18%, signal=45%
229	INOH_P38 CASCADE		12	-0.58	-1.21	0.256	0.423	1.000	1328	tags=25%, list=6%, signal=27%
230	NCI_GLYPICAN 3 NETWORK		57	-0.43	-1.21	0.171	0.424	1.000	3264	tags=33%, list=15%, signal=39%
231	BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART		42	-0.45	-1.21	0.178	0.429	1.000	3225	tags=24%, list=15%, signal=28%
232	NCI_S1P2 PATHWAY		23	-0.51	-1.21	0.231	0.427	1.000	2645	tags=26%, list=12%, signal=30%
233	REACTOME_EGFR_DOWNREGULATION		11	-0.57	-1.20	0.273	0.428	1.000	2942	tags=36%, list=13%, signal=42%
234	CELLMAP_EGFR1		122	-0.39	-1.20	0.164	0.431	1.000	3653	tags=34%, list=17%, signal=40%
235	REACTOME_CELL_CYCLE_CHECKPOINTS		77	-0.39	-1.20	0.177	0.431	1.000	387	tags=12%, list=2%, signal=12%
236	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)		26	-0.49	-1.20	0.227	0.431	1.000	3457	tags=38%, list=16%, signal=46%
237	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	-0.54	-1.20	0.242	0.430	1.000	2575	tags=44%, list=12%, signal=50%
238	BIOCARTA_SEGMENTATION CLOCK		20	-0.52	-1.20	0.264	0.430	1.000	3264	tags=35%, list=15%, signal=41%
239	BIOCARTA_APOPTOTIC DNA-FRAGMENTATION AND TISSUE HOMEOSTASIS		10	-0.60	-1.20	0.279	0.431	1.000	1242	tags=30%, list=6%, signal=32%
240	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS		19	-0.53	-1.19	0.229	0.439	1.000	935	tags=21%, list=4%, signal=22%
241	REACTOME_ORNITHINE_AND_PROLINE_METABOLISM		45	-0.44	-1.19	0.198	0.446	1.000	387	tags=16%, list=2%, signal=16%
242	REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE		40	-0.45	-1.18	0.197	0.451	1.000	387	tags=18%, list=2%, signal=18%
243	REACTOME_P53_DEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT		40	-0.45	-1.18	0.228	0.458	1.000	387	tags=18%, list=2%, signal=18%
244	NCI_REELIN SIGNALING PATHWAY		27	-0.49	-1.18	0.221	0.463	1.000	4011	tags=37%, list=18%, signal=45%
245	REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_		46	-0.44	-1.18	0.232	0.464	1.000	387	tags=15%, list=2%, signal=15%
246	NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA		57	-0.41	-1.17	0.215	0.466	1.000	3718	tags=32%, list=17%, signal=38%
247	REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS		19	-0.51	-1.17	0.262	0.467	1.000	3991	tags=37%, list=18%, signal=45%
248	REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS		41	-0.44	-1.17	0.234	0.465	1.000	387	tags=17%, list=2%, signal=17%
249	NCI_P75(NTR)-MEDIATED SIGNALING		165	-0.36	-1.17	0.155	0.466	1.000	3729	tags=33%, list=17%, signal=39%
250	NCI_IL2-MEDIATED SIGNALING EVENTS		108	-0.37	-1.17	0.175	0.465	1.000	2864	tags=31%, list=13%, signal=36%
251	INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY		132	-0.37	-1.16	0.162	0.476	1.000	4037	tags=36%, list=18%, signal=43%
252	BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING		32	-0.46	-1.16	0.257	0.475	1.000	2464	tags=25%, list=11%, signal=28%
253	NCI_CANONICAL WNT SIGNALING PATHWAY		49	-0.42	-1.16	0.211	0.473	1.000	1391	tags=20%, list=6%, signal=22%
254	NCI_ANDROGEN-MEDIATED SIGNALING		105	-0.38	-1.16	0.205	0.474	1.000	2782	tags=24%, list=13%, signal=27%
255	NCI_WNT SIGNALING		49	-0.42	-1.16	0.209	0.482	1.000	1391	tags=20%, list=6%, signal=22%
256	BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES		15	-0.53	-1.16	0.284	0.482	1.000	2379	tags=33%, list=11%, signal=37%
257	CELLMAP_TGFBR		105	-0.37	-1.15	0.229	0.492	1.000	1399	tags=14%, list=6%, signal=15%
258	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT		59	-0.40	-1.15	0.233	0.495	1.000	1183	tags=12%, list=5%, signal=13%
259	NCI_THROMBOXANE A2 RECEPTOR SIGNALING		50	-0.41	-1.15	0.253	0.496	1.000	4161	tags=34%, list=19%, signal=42%
260	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		194	-0.34	-1.15	0.182	0.494	1.000	4161	tags=30%, list=19%, signal=37%
261	NCI_MTOR SIGNALING PATHWAY		23	-0.48	-1.14	0.284	0.496	1.000	241	tags=9%, list=1%, signal=9%
262	REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE		47	-0.42	-1.14	0.235	0.495	1.000	387	tags=15%, list=2%, signal=15%
263	BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA		36	-0.44	-1.14	0.254	0.494	1.000	2638	tags=25%, list=12%, signal=28%
264	REACTOME_REGULATION_OF_DNA_REPLICATION		50	-0.41	-1.14	0.271	0.492	1.000	726	tags=16%, list=3%, signal=17%
265	NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING		46	-0.43	-1.14	0.277	0.493	1.000	2379	tags=24%, list=11%, signal=27%
266	REACTOME_MITOTIC_PROMETAPHASE		38	-0.43	-1.14	0.269	0.494	1.000	2092	tags=24%, list=10%, signal=26%
267	REACTOME_DOWNSTREAM_TCR_SIGNALING		20	-0.49	-1.14	0.290	0.494	1.000	2575	tags=40%, list=12%, signal=45%
268	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1		12	-0.55	-1.14	0.313	0.493	1.000	2801	tags=33%, list=13%, signal=38%
269	REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE		37	-0.43	-1.14	0.264	0.491	1.000	2937	tags=38%, list=13%, signal=44%
270	NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS		13	-0.53	-1.14	0.316	0.493	1.000	3110	tags=38%, list=14%, signal=45%
271	REACTOME_SIGNALLING_BY_NGF		64	-0.39	-1.14	0.244	0.492	1.000	2942	tags=30%, list=13%, signal=34%
272	REACTOME_ORC1_REMOVAL_FROM_CHROMATIN		47	-0.42	-1.14	0.273	0.492	1.000	387	tags=15%, list=2%, signal=15%
273	NCI_EPO SIGNALING PATHWAY		31	-0.45	-1.13	0.308	0.502	1.000	3522	tags=39%, list=16%, signal=46%
274	REACTOME_REMOVAL_OF_LICENSING_FACTORS_FROM_ORIGINS		49	-0.41	-1.13	0.287	0.502	1.000	387	tags=14%, list=2%, signal=15%
275	BIOCARTA_NF-KB SIGNALING PATHWAY		21	-0.48	-1.13	0.320	0.502	1.000	2699	tags=29%, list=12%, signal=33%
276	NETPATH_IFN-ALPHA		44	-0.42	-1.13	0.255	0.502	1.000	2864	tags=34%, list=13%, signal=39%
277	CELLMAP_WNT		66	-0.39	-1.13	0.258	0.502	1.000	3991	tags=30%, list=18%, signal=37%
278	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION		14	-0.52	-1.12	0.336	0.507	1.000	4074	tags=43%, list=19%, signal=53%
279	NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7		22	-0.47	-1.12	0.310	0.512	1.000	4362	tags=45%, list=20%, signal=57%
280	BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES		24	-0.47	-1.12	0.311	0.512	1.000	3991	tags=50%, list=18%, signal=61%
281	INOH_GENE EXPRESSION OF SMAD7 BY R-SMAD:SMAD4		35	-0.43	-1.12	0.296	0.512	1.000	1340	tags=17%, list=6%, signal=18%
282	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY		120	-0.36	-1.12	0.226	0.511	1.000	2932	tags=26%, list=13%, signal=30%
283	NCI_VISUAL SIGNAL TRANSDUCTION: RODS		18	-0.49	-1.12	0.330	0.510	1.000	701	tags=11%, list=3%, signal=11%
284	REACTOME_PLATELET_ACTIVATION_TRIGGERS		24	-0.47	-1.12	0.333	0.511	1.000	2645	tags=33%, list=12%, signal=38%
285	REACTOME_LOSS_OF_PROTEINS_REQUIRED_FOR_INTERPHASE_MICROTUBULE_ORGANIZATION_FROM_THE_CENTROSOME		38	-0.43	-1.11	0.310	0.514	1.000	1184	tags=16%, list=5%, signal=17%
286	REACTOME_PI3K_AKT_SIGNALLING		13	-0.54	-1.11	0.333	0.515	1.000	3636	tags=46%, list=17%, signal=55%
287	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE)		183	-0.34	-1.10	0.226	0.531	1.000	2477	tags=11%, list=11%, signal=12%
288	REACTOME_M_PHASE		40	-0.41	-1.10	0.320	0.530	1.000	2092	tags=23%, list=10%, signal=25%
289	BIOCARTA_CTCF: FIRST MULTIVALENT NUCLEAR FACTOR		22	-0.47	-1.10	0.355	0.530	1.000	2271	tags=27%, list=10%, signal=30%
290	BIOCARTA_INTEGRIN SIGNALING PATHWAY		33	-0.42	-1.10	0.309	0.530	1.000	4261	tags=33%, list=19%, signal=41%
291	BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE		28	-0.44	-1.10	0.319	0.532	1.000	2699	tags=25%, list=12%, signal=28%
292	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS		10	-0.56	-1.10	0.360	0.537	1.000	4079	tags=60%, list=19%, signal=74%
293	REACTOME_SIGNALING_BY_GPCR		139	-0.34	-1.10	0.260	0.536	1.000	2645	tags=12%, list=12%, signal=13%
294	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		28	-0.44	-1.09	0.318	0.539	1.000	2932	tags=29%, list=13%, signal=33%
295	INOH_NEGATIVE FEEDBACK REGULATION OF TGF BETA SUPERFAMILY SIGNALING PATHWAY BY R-SMAD DAGRADATION		40	-0.42	-1.09	0.341	0.547	1.000	1340	tags=15%, list=6%, signal=16%
296	REACTOME_PAUSING_AND_RECOVERY_OF_TAT_MEDIATED_HIV_1_ELONGATION		22	-0.46	-1.09	0.354	0.549	1.000	724	tags=14%, list=3%, signal=14%
297	INOH_SIGNALING WITH WNT (MAMMAL)		53	-0.40	-1.08	0.327	0.550	1.000	3844	tags=25%, list=18%, signal=30%
298	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		14	-0.49	-1.08	0.380	0.549	1.000	5016	tags=50%, list=23%, signal=65%
299	BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		15	-0.50	-1.08	0.396	0.551	1.000	427	tags=13%, list=2%, signal=14%
300	REACTOME_TCR_SIGNALING		33	-0.42	-1.08	0.351	0.553	1.000	2575	tags=33%, list=12%, signal=38%
301	REACTOME_TAT_MEDIATED_HIV_1_ELONGATION_ARREST_AND_RECOVERY_		22	-0.46	-1.08	0.364	0.552	1.000	724	tags=14%, list=3%, signal=14%
302	NCI_NECTIN ADHESION PATHWAY		99	-0.35	-1.08	0.335	0.560	1.000	2159	tags=23%, list=10%, signal=26%
303	REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_		32	-0.41	-1.07	0.359	0.566	1.000	724	tags=13%, list=3%, signal=13%
304	REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES		64	-0.37	-1.07	0.325	0.564	1.000	1183	tags=11%, list=5%, signal=12%
305	HUMANCYC_VALINE DEGRADATION I		10	-0.53	-1.07	0.386	0.567	1.000	2809	tags=50%, list=13%, signal=57%
306	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		14	-0.49	-1.07	0.358	0.567	1.000	5016	tags=50%, list=23%, signal=65%
307	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		72	-0.36	-1.07	0.334	0.566	1.000	2011	tags=19%, list=9%, signal=21%
308	BIOCARTA_THE PRC2 COMPLEX SETS LONG-TERM GENE SILENCING THROUGH MODIFICATION OF HISTONE TAILS		13	-0.50	-1.07	0.408	0.568	1.000	2466	tags=31%, list=11%, signal=35%
309	INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS)		12	-0.52	-1.07	0.407	0.568	1.000	2379	tags=25%, list=11%, signal=28%
310	REACTOME_HIV_INFECTION		128	-0.33	-1.06	0.314	0.567	1.000	755	tags=11%, list=3%, signal=11%
311	BIOCARTA_REGULATION OF PGC-1A		18	-0.47	-1.06	0.386	0.566	1.000	4005	tags=44%, list=18%, signal=54%
312	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER		13	-0.49	-1.06	0.401	0.568	1.000	4074	tags=38%, list=19%, signal=47%
313	BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS		22	-0.45	-1.06	0.378	0.570	1.000	2379	tags=18%, list=11%, signal=20%
314	BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF)		16	-0.48	-1.06	0.386	0.569	1.000	2379	tags=31%, list=11%, signal=35%
315	BIOCARTA_BONE REMODELING		15	-0.49	-1.06	0.420	0.571	1.000	2699	tags=27%, list=12%, signal=30%
316	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE)		198	-0.32	-1.06	0.324	0.570	1.000	2645	tags=12%, list=12%, signal=13%
317	REACTOME_PEROXISOMAL_LIPID_METABOLISM		11	-0.51	-1.06	0.412	0.569	1.000	4639	tags=55%, list=21%, signal=69%
318	BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY		28	-0.43	-1.06	0.383	0.568	1.000	4378	tags=43%, list=20%, signal=53%
319	NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING		38	-0.40	-1.06	0.387	0.570	1.000	2638	tags=24%, list=12%, signal=27%
320	INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING		35	-0.41	-1.05	0.384	0.571	1.000	3070	tags=17%, list=14%, signal=20%
321	BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE		20	-0.45	-1.05	0.369	0.570	1.000	1126	tags=15%, list=5%, signal=16%
322	NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT		24	-0.43	-1.05	0.394	0.582	1.000	3703	tags=33%, list=17%, signal=40%
323	REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_		90	-0.34	-1.04	0.355	0.585	1.000	2445	tags=10%, list=11%, signal=11%
324	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_ELONGATION		32	-0.41	-1.04	0.415	0.588	1.000	724	tags=13%, list=3%, signal=13%
325	BIOCARTA_FIBRINOLYSIS PATHWAY		12	-0.50	-1.04	0.429	0.588	1.000	2081	tags=25%, list=9%, signal=28%
326	NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS		49	-0.38	-1.04	0.408	0.588	1.000	2011	tags=20%, list=9%, signal=22%
327	NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA		66	-0.36	-1.04	0.378	0.590	1.000	3636	tags=35%, list=17%, signal=42%
328	INOH_B-RAF ACTIVATION SIGNALING		29	-0.41	-1.04	0.413	0.594	1.000	2379	tags=24%, list=11%, signal=27%
329	BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION		46	-0.38	-1.04	0.388	0.593	1.000	2379	tags=28%, list=11%, signal=32%
330	BIOCARTA_TGF BETA SIGNALING PATHWAY		20	-0.45	-1.03	0.418	0.597	1.000	2638	tags=25%, list=12%, signal=28%
331	NCI_IL23-MEDIATED SIGNALING EVENTS		60	-0.36	-1.03	0.385	0.596	1.000	3356	tags=30%, list=15%, signal=35%
332	INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING		107	-0.34	-1.03	0.397	0.595	1.000	2379	tags=17%, list=11%, signal=19%
333	NCI_CERAMIDE SIGNALING PATHWAY		42	-0.39	-1.03	0.412	0.596	1.000	2828	tags=31%, list=13%, signal=35%
334	NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5		27	-0.42	-1.03	0.433	0.603	1.000	2477	tags=30%, list=11%, signal=33%
335	BIOCARTA_CELL TO CELL ADHESION SIGNALING		12	-0.49	-1.03	0.436	0.603	1.000	6004	tags=75%, list=27%, signal=103%
336	NCI_FGF SIGNALING PATHWAY		46	-0.37	-1.02	0.402	0.605	1.000	1861	tags=20%, list=8%, signal=21%
337	INOH_IKK-NF-KAPPAB CASCADE		12	-0.48	-1.02	0.429	0.604	1.000	2213	tags=25%, list=10%, signal=28%
338	BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING		35	-0.40	-1.02	0.445	0.604	1.000	2937	tags=26%, list=13%, signal=30%
339	BIOCARTA_MTOR SIGNALING PATHWAY		22	-0.43	-1.02	0.425	0.604	1.000	2675	tags=23%, list=12%, signal=26%
340	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	-0.31	-1.02	0.418	0.609	1.000	4037	tags=27%, list=18%, signal=33%
341	REACTOME_CENTROSOME_MATURATION		40	-0.38	-1.02	0.446	0.607	1.000	1184	tags=15%, list=5%, signal=16%
342	NCI_HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK		56	-0.36	-1.02	0.444	0.609	1.000	3636	tags=36%, list=17%, signal=43%
343	BIOCARTA_CONTROL OF GENE EXPRESSION BY VITAMIN D RECEPTOR		24	-0.41	-1.01	0.427	0.610	1.000	2970	tags=38%, list=14%, signal=43%
344	BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR		17	-0.45	-1.01	0.438	0.610	1.000	1328	tags=18%, list=6%, signal=19%
345	INOH_TGF-BETA_SUPER_FAMILY_SIGNALING_PATHWAY(CANONICAL)		78	-0.35	-1.01	0.440	0.609	1.000	1340	tags=10%, list=6%, signal=11%
346	INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL)		189	-0.30	-1.01	0.421	0.610	1.000	2801	tags=12%, list=13%, signal=13%
347	BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY		14	-0.47	-1.01	0.459	0.610	1.000	42	tags=7%, list=0%, signal=7%
348	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC)		25	-0.42	-1.01	0.459	0.611	1.000	2379	tags=24%, list=11%, signal=27%
349	INOH_TGF BETA RECEPTOR I DEGRADATION SIGNALING		25	-0.42	-1.01	0.463	0.615	1.000	216	tags=12%, list=1%, signal=12%
350	BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING		32	-0.40	-1.01	0.459	0.613	1.000	2379	tags=25%, list=11%, signal=28%
351	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE)		19	-0.43	-1.00	0.445	0.616	1.000	1328	tags=16%, list=6%, signal=17%
352	BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY		30	-0.41	-1.00	0.457	0.615	1.000	4719	tags=43%, list=22%, signal=55%
353	INOH_SIGNALING WITH WNT (XENOPUS)		15	-0.46	-1.00	0.438	0.617	1.000	1930	tags=20%, list=9%, signal=22%
354	NETPATH_IFN-GAMMA		71	-0.34	-1.00	0.446	0.618	1.000	3038	tags=32%, list=14%, signal=37%
355	BIOCARTA_RAS SIGNALING PATHWAY		19	-0.43	-1.00	0.471	0.620	1.000	5564	tags=53%, list=25%, signal=70%
356	INOH_TGF BETA RECEPTOR COMPLEX DEGRADATION SIGNALING		29	-0.40	-1.00	0.470	0.622	1.000	216	tags=10%, list=1%, signal=10%
357	BIOCARTA_ATTENUATION OF GPCR SIGNALING		11	-0.49	-1.00	0.481	0.621	1.000	3653	tags=45%, list=17%, signal=55%
358	INOH_SIGNALING WITH WNT (CANONICAL)		57	-0.35	-1.00	0.474	0.622	1.000	3844	tags=23%, list=18%, signal=28%
359	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION		19	-0.43	-0.99	0.488	0.622	1.000	4074	tags=32%, list=19%, signal=39%
360	BIOCARTA_ADP-RIBOSYLATION FACTOR		18	-0.44	-0.99	0.467	0.623	1.000	625	tags=17%, list=3%, signal=17%
361	REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL		23	-0.42	-0.99	0.492	0.625	1.000	2639	tags=26%, list=12%, signal=30%
362	REACTOME_PYRIMIDINE_METABOLISM		17	-0.45	-0.99	0.502	0.629	1.000	1025	tags=18%, list=5%, signal=18%
363	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS)		15	-0.46	-0.99	0.480	0.629	1.000	1930	tags=20%, list=9%, signal=22%
364	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH		18	-0.43	-0.99	0.477	0.631	1.000	3978	tags=39%, list=18%, signal=47%
365	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE)		20	-0.43	-0.98	0.496	0.631	1.000	1328	tags=15%, list=6%, signal=16%
366	BIOCARTA_EFFECTS OF CALCINEURIN IN KERATINOCYTE DIFFERENTIATION		12	-0.47	-0.98	0.520	0.638	1.000	214	tags=17%, list=1%, signal=17%
367	BIOCARTA_WNT SIGNALING PATHWAY		27	-0.40	-0.98	0.476	0.638	1.000	3591	tags=30%, list=16%, signal=35%
368	INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN)		173	-0.30	-0.98	0.509	0.638	1.000	2645	tags=10%, list=12%, signal=11%
369	BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION		21	-0.42	-0.98	0.493	0.640	1.000	3653	tags=38%, list=17%, signal=46%
370	REACTOME_SPHINGOLIPID_METABOLISM		10	-0.49	-0.97	0.510	0.641	1.000	3529	tags=50%, list=16%, signal=60%
371	NETPATH_GDNF		29	-0.39	-0.97	0.492	0.640	1.000	3978	tags=31%, list=18%, signal=38%
372	INOH_JAK DEGRADATION SIGNALING		24	-0.41	-0.97	0.483	0.639	1.000	1076	tags=17%, list=5%, signal=18%
373	NCI_LPA4-MEDIATED SIGNALING EVENTS		14	-0.45	-0.97	0.539	0.639	1.000	3636	tags=29%, list=17%, signal=34%
374	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP)		173	-0.30	-0.97	0.530	0.638	1.000	2645	tags=10%, list=12%, signal=11%
375	REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES		40	-0.38	-0.97	0.500	0.637	1.000	1184	tags=15%, list=5%, signal=16%
376	HUMANCYC_TRIACYLGLYCEROL DEGRADATION		12	-0.47	-0.97	0.522	0.637	1.000	3075	tags=25%, list=14%, signal=29%
377	NCI_EPHB FORWARD SIGNALING		37	-0.38	-0.97	0.501	0.638	1.000	5932	tags=46%, list=27%, signal=63%
378	REACTOME_CD28_CO_STIMULATION		13	-0.46	-0.97	0.524	0.636	1.000	5293	tags=62%, list=24%, signal=81%
379	NETPATH_TIE1_TEK		25	-0.39	-0.97	0.471	0.641	1.000	3522	tags=28%, list=16%, signal=33%
380	BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES		30	-0.38	-0.96	0.494	0.645	1.000	2379	tags=17%, list=11%, signal=19%
381	NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT		84	-0.32	-0.96	0.523	0.652	1.000	3356	tags=27%, list=15%, signal=32%
382	INOH_PKA ACTIVATION SIGNALING		49	-0.34	-0.96	0.531	0.656	1.000	3636	tags=29%, list=17%, signal=34%
383	BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R		35	-0.37	-0.96	0.530	0.655	1.000	2979	tags=23%, list=14%, signal=26%
384	REACTOME_PURINE_BIOSYNTHESIS		26	-0.39	-0.96	0.550	0.655	1.000	107	tags=8%, list=0%, signal=8%
385	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G)		13	-0.45	-0.96	0.532	0.653	1.000	2379	tags=31%, list=11%, signal=34%
386	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		15	-0.43	-0.95	0.531	0.656	1.000	2638	tags=40%, list=12%, signal=45%
387	INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP)		177	-0.29	-0.95	0.588	0.662	1.000	3308	tags=12%, list=15%, signal=14%
388	NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS		47	-0.35	-0.95	0.562	0.662	1.000	3529	tags=32%, list=16%, signal=38%
389	BIOCARTA_VISUAL SIGNAL TRANSDUCTION		13	-0.45	-0.95	0.537	0.665	1.000	454	tags=8%, list=2%, signal=8%
390	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE		14	-0.44	-0.94	0.543	0.666	1.000	416	tags=14%, list=2%, signal=15%
391	CELLMAP_KITRECEPTOR		49	-0.34	-0.94	0.565	0.665	1.000	3549	tags=35%, list=16%, signal=41%
392	HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION		32	-0.37	-0.94	0.545	0.663	1.000	123	tags=6%, list=1%, signal=6%
393	NETPATH_IL1		27	-0.38	-0.94	0.541	0.666	1.000	3723	tags=26%, list=17%, signal=31%
394	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE DEOXYRIBONUCLEOTIDES		12	-0.45	-0.94	0.526	0.664	1.000	865	tags=17%, list=4%, signal=17%
395	INOH_SNON DEGRADATION SIGNALING		25	-0.39	-0.94	0.537	0.672	1.000	76	tags=8%, list=0%, signal=8%
396	REACTOME_SIGNALING_IN_IMMUNE_SYSTEM		138	-0.29	-0.93	0.615	0.673	1.000	2829	tags=20%, list=13%, signal=23%
397	INOH_CYTOKINE RECEPTOR DEGRADATION SIGNALING		20	-0.41	-0.93	0.574	0.672	1.000	76	tags=10%, list=0%, signal=10%
398	BIOCARTA_IL 6 SIGNALING PATHWAY		13	-0.44	-0.93	0.566	0.680	1.000	3522	tags=38%, list=16%, signal=46%
399	BIOCARTA_ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE PKA		26	-0.38	-0.93	0.557	0.680	1.000	3653	tags=31%, list=17%, signal=37%
400	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION		11	-0.45	-0.93	0.545	0.680	1.000	413	tags=9%, list=2%, signal=9%
401	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING		17	-0.41	-0.93	0.576	0.679	1.000	4313	tags=35%, list=20%, signal=44%
402	BIOCARTA_STATHMIN AND BREAST CANCER RESISTANCE TO ANTIMICROTUBULE AGENTS		16	-0.42	-0.93	0.578	0.680	1.000	504	tags=13%, list=2%, signal=13%
403	BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION		16	-0.43	-0.92	0.571	0.682	1.000	2379	tags=31%, list=11%, signal=35%
404	BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS		21	-0.39	-0.92	0.563	0.681	1.000	2081	tags=19%, list=9%, signal=21%
405	NCI_INTEGRINS IN ANGIOGENESIS		62	-0.32	-0.92	0.599	0.685	1.000	2379	tags=21%, list=11%, signal=23%
406	BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES		25	-0.38	-0.92	0.578	0.694	1.000	2379	tags=24%, list=11%, signal=27%
407	BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION		26	-0.38	-0.92	0.595	0.692	1.000	2464	tags=19%, list=11%, signal=22%
408	NCI_AURORA B SIGNALING		35	-0.35	-0.91	0.604	0.692	1.000	928	tags=11%, list=4%, signal=12%
409	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS		54	-0.32	-0.91	0.626	0.694	1.000	2445	tags=9%, list=11%, signal=10%
410	REACTOME_TOLL_LIKE_RECEPTOR_4__TLR4__CASCADE		10	-0.46	-0.91	0.579	0.693	1.000	3740	tags=40%, list=17%, signal=48%
411	NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY		62	-0.32	-0.91	0.606	0.696	1.000	3529	tags=29%, list=16%, signal=35%
412	BIOCARTA_CHREBP REGULATION BY CARBOHYDRATES AND CAMP		37	-0.35	-0.91	0.602	0.697	1.000	3653	tags=27%, list=17%, signal=32%
413	BIOCARTA_OVERVIEW OF TELOMERASE PROTEIN COMPONENT GENE HTERT TRANSCRIPTIONAL REGULATION		10	-0.45	-0.91	0.605	0.696	1.000	555	tags=20%, list=3%, signal=21%
414	INOH_PLC BETA SIGNALING		19	-0.39	-0.91	0.585	0.698	1.000	2379	tags=26%, list=11%, signal=29%
415	NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY		84	-0.30	-0.91	0.654	0.697	1.000	2782	tags=20%, list=13%, signal=23%
416	BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK)		19	-0.39	-0.91	0.599	0.695	1.000	4005	tags=42%, list=18%, signal=51%
417	BIOCARTA_THE INFORMATION PROCESSING PATHWAY AT THE IFN BETA ENHANCER		27	-0.36	-0.90	0.633	0.695	1.000	2688	tags=26%, list=12%, signal=30%
418	BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY		16	-0.41	-0.90	0.639	0.698	1.000	3991	tags=44%, list=18%, signal=53%
419	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II		31	-0.35	-0.90	0.621	0.702	1.000	2726	tags=29%, list=12%, signal=33%
420	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING		13	-0.41	-0.90	0.617	0.702	1.000	34	tags=8%, list=0%, signal=8%
421	BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM		14	-0.42	-0.89	0.596	0.711	1.000	3653	tags=50%, list=17%, signal=60%
422	BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE		14	-0.42	-0.89	0.631	0.710	1.000	210	tags=14%, list=1%, signal=14%
423	INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING		11	-0.43	-0.89	0.598	0.709	1.000	3308	tags=36%, list=15%, signal=43%
424	BIOCARTA_THE IGF-1 RECEPTOR AND LONGEVITY		15	-0.40	-0.88	0.646	0.723	1.000	420	tags=13%, list=2%, signal=14%
425	NCI_EPHRINB-EPHB PATHWAY		53	-0.32	-0.88	0.699	0.728	1.000	2464	tags=19%, list=11%, signal=21%
426	BIOCARTA_REGULATION OF P27 PHOSPHORYLATION DURING CELL CYCLE PROGRESSION		11	-0.41	-0.87	0.644	0.737	1.000	185	tags=18%, list=1%, signal=18%
427	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		30	-0.35	-0.87	0.628	0.736	1.000	2428	tags=27%, list=11%, signal=30%
428	BIOCARTA_CHROMATIN REMODELING BY HSWI/SNF ATP-DEPENDENT COMPLEXES		16	-0.40	-0.87	0.637	0.736	1.000	1623	tags=25%, list=7%, signal=27%
429	REACTOME_TAT_MEDIATED_ELONGATION_OF_THE_HIV_1_TRANSCRIPT		31	-0.34	-0.87	0.671	0.736	1.000	724	tags=10%, list=3%, signal=10%
430	REACTOME_FORMATION_OF_HIV_1_ELONGATION_COMPLEX_CONTAINING_HIV_1_TAT		31	-0.34	-0.87	0.677	0.738	1.000	724	tags=10%, list=3%, signal=10%
431	REACTOME_HIV_1_TRANSCRIPTION_ELONGATION		31	-0.34	-0.87	0.671	0.742	1.000	724	tags=10%, list=3%, signal=10%
432	REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS		11	-0.42	-0.86	0.635	0.747	1.000	262	tags=9%, list=1%, signal=9%
433	NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES		21	-0.37	-0.86	0.667	0.747	1.000	4459	tags=43%, list=20%, signal=54%
434	BIOCARTA_CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) AND BETA 2 ADRENERGIC RECEPTOR (B2AR) PATHWAY		18	-0.38	-0.86	0.676	0.749	1.000	3653	tags=39%, list=17%, signal=47%
435	BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM		19	-0.38	-0.86	0.647	0.750	1.000	2638	tags=21%, list=12%, signal=24%
436	REACTOME_TOLL_RECEPTOR_CASCADES		27	-0.35	-0.85	0.711	0.764	1.000	2821	tags=22%, list=13%, signal=25%
437	REACTOME_SHC_RELATED_EVENTS		10	-0.42	-0.84	0.673	0.771	1.000	2379	tags=30%, list=11%, signal=34%
438	BIOCARTA_SKELETAL MUSCLE HYPERTROPHY IS REGULATED VIA AKT-MTOR PATHWAY		24	-0.35	-0.84	0.712	0.770	1.000	538	tags=8%, list=2%, signal=9%
439	NCI_S1P4 PATHWAY		12	-0.39	-0.84	0.662	0.771	1.000	2645	tags=33%, list=12%, signal=38%
440	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		26	-0.34	-0.84	0.698	0.774	1.000	4378	tags=42%, list=20%, signal=53%
441	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE		12	-0.40	-0.84	0.668	0.777	1.000	1601	tags=25%, list=7%, signal=27%
442	REACTOME_CYTOCHROME_P450___ARRANGED_BY_SUBSTRATE_TYPE		20	-0.36	-0.83	0.697	0.780	1.000	2873	tags=15%, list=13%, signal=17%
443	BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS		20	-0.35	-0.82	0.726	0.800	1.000	2379	tags=25%, list=11%, signal=28%
444	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II		27	-0.34	-0.82	0.734	0.802	1.000	2043	tags=15%, list=9%, signal=16%
445	REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS		15	-0.37	-0.81	0.712	0.808	1.000	4931	tags=40%, list=22%, signal=52%
446	BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS		25	-0.32	-0.80	0.753	0.820	1.000	3991	tags=32%, list=18%, signal=39%
447	REACTOME_SIGNALLING_TO_RAS		12	-0.38	-0.80	0.715	0.828	1.000	2379	tags=25%, list=11%, signal=28%
448	REACTOME_SIGNALING_BY_EGFR		28	-0.32	-0.79	0.764	0.835	1.000	3522	tags=32%, list=16%, signal=38%
449	BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION		13	-0.36	-0.79	0.751	0.836	1.000	3225	tags=23%, list=15%, signal=27%
450	REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM		12	-0.38	-0.79	0.738	0.836	1.000	2804	tags=33%, list=13%, signal=38%
451	BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES		37	-0.30	-0.78	0.819	0.842	1.000	3264	tags=27%, list=15%, signal=32%
452	INOH_MAMMALIAN WNT SIGNALING PATHWAY		70	-0.26	-0.77	0.880	0.850	1.000	1930	tags=11%, list=9%, signal=12%
453	NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2		65	-0.27	-0.77	0.881	0.859	1.000	2417	tags=14%, list=11%, signal=16%
454	REACTOME_HORMONE_BIOSYNTHESIS		31	-0.30	-0.76	0.828	0.866	1.000	3535	tags=19%, list=16%, signal=23%
455	NCI_VISUAL SIGNAL TRANSDUCTION: CONES		16	-0.35	-0.76	0.800	0.867	1.000	701	tags=6%, list=3%, signal=6%
456	NCI_VEGFR3 SIGNALING IN LYMPHATIC ENDOTHELIUM		24	-0.31	-0.76	0.815	0.866	1.000	4161	tags=29%, list=19%, signal=36%
457	INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		10	-0.38	-0.75	0.789	0.872	1.000	4161	tags=50%, list=19%, signal=62%
458	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_ALPHA__PPARALPHA_		11	-0.37	-0.75	0.782	0.871	1.000	3845	tags=18%, list=18%, signal=22%
459	REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING		10	-0.38	-0.74	0.784	0.881	1.000	2379	tags=30%, list=11%, signal=34%
460	REACTOME_STEROID_HORMONES		14	-0.34	-0.73	0.841	0.888	1.000	2873	tags=21%, list=13%, signal=25%
461	REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING		11	-0.35	-0.72	0.841	0.899	1.000	2379	tags=27%, list=11%, signal=31%
462	BIOCARTA_ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM		42	-0.26	-0.71	0.917	0.906	1.000	2464	tags=12%, list=11%, signal=13%
463	REACTOME_SIGNALLING_TO_ERKS		14	-0.33	-0.71	0.852	0.907	1.000	2379	tags=21%, list=11%, signal=24%
464	BIOCARTA_AKT SIGNALING PATHWAY		14	-0.33	-0.71	0.849	0.907	1.000	3225	tags=29%, list=15%, signal=33%
465	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS		11	-0.34	-0.70	0.824	0.907	1.000	5016	tags=45%, list=23%, signal=59%
466	REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE		13	-0.33	-0.68	0.888	0.926	1.000	2816	tags=23%, list=13%, signal=26%
467	REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE		15	-0.32	-0.68	0.877	0.926	1.000	2816	tags=20%, list=13%, signal=23%
468	REACTOME_TIE2_SIGNALING		12	-0.32	-0.68	0.860	0.927	1.000	5315	tags=50%, list=24%, signal=66%
469	BIOCARTA_IL 4 SIGNALING PATHWAY		11	-0.33	-0.66	0.870	0.937	1.000	2479	tags=27%, list=11%, signal=31%
470	REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S		13	-0.31	-0.66	0.885	0.936	1.000	3119	tags=23%, list=14%, signal=27%
471	REACTOME_MRNA_PROCESSING		27	-0.26	-0.66	0.921	0.935	1.000	660	tags=7%, list=3%, signal=8%
472	BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN		15	-0.29	-0.62	0.926	0.954	1.000	2963	tags=27%, list=14%, signal=31%
473	REACTOME_ENDOGENOUS_STEROLS		10	-0.29	-0.58	0.921	0.969	1.000	15666	tags=100%, list=71%, signal=350%