Table: Gene sets enriched in phenotype normalThy (4 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Details ...	13	-0.97	-1.70	0.000	0.136	0.116	78	tags=23%, list=0%, signal=23%
2	BIOCARTA_TNF/STRESS RELATED SIGNALING	Details ...	22	-0.87	-1.67	0.002	0.134	0.211	2074	tags=59%, list=11%, signal=66%
3	NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS	Details ...	108	-0.65	-1.65	0.000	0.164	0.347	2054	tags=36%, list=11%, signal=40%
4	NCI_REELIN SIGNALING PATHWAY	Details ...	27	-0.82	-1.62	0.002	0.217	0.526	2054	tags=33%, list=11%, signal=37%
5	NCI_SIGNALING BY AURORA KINASES	Details ...	85	-0.66	-1.59	0.003	0.303	0.730	2001	tags=29%, list=11%, signal=33%
6	BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART	Details ...	39	-0.73	-1.59	0.013	0.268	0.755	871	tags=10%, list=5%, signal=11%
7	BIOCARTA_KERATINOCYTE DIFFERENTIATION	Details ...	51	-0.69	-1.57	0.002	0.313	0.856	2074	tags=33%, list=11%, signal=37%
8	NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS	Details ...	48	-0.72	-1.56	0.008	0.305	0.886	2054	tags=40%, list=11%, signal=44%
9	NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS	Details ...	118	-0.62	-1.56	0.000	0.283	0.890	2074	tags=35%, list=11%, signal=39%
10	NCI_IL2-MEDIATED SIGNALING EVENTS	Details ...	112	-0.61	-1.54	0.000	0.336	0.939	2054	tags=31%, list=11%, signal=35%
11	NCI_AURORA B SIGNALING	Details ...	33	-0.74	-1.53	0.018	0.374	0.969	1996	tags=27%, list=11%, signal=30%
12	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II	Details ...	31	-0.76	-1.53	0.021	0.372	0.977	1424	tags=19%, list=8%, signal=21%
13	REACTOME_STEROID_HORMONES	Details ...	13	-0.88	-1.52	0.008	0.344	0.977	141	tags=8%, list=1%, signal=8%
14	REACTOME_DOWNSTREAM_TCR_SIGNALING	Details ...	19	-0.82	-1.52	0.018	0.363	0.983	2465	tags=79%, list=13%, signal=91%
15	NCI_CANONICAL NF-KAPPAB PATHWAY	Details ...	35	-0.73	-1.51	0.002	0.345	0.985	2001	tags=34%, list=11%, signal=38%
16	BIOCARTA_TNFR2 SIGNALING PATHWAY	Details ...	12	-0.89	-1.50	0.019	0.399	0.997	1784	tags=67%, list=10%, signal=74%
17	NCI_PDGFR-ALPHA SIGNALING PATHWAY	Details ...	20	-0.79	-1.50	0.032	0.381	0.997	429	tags=10%, list=2%, signal=10%
18	BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY	Details ...	16	-0.83	-1.50	0.015	0.373	0.997	728	tags=19%, list=4%, signal=19%
19	NCI_IL12-MEDIATED SIGNALING EVENTS	Details ...	104	-0.60	-1.49	0.005	0.372	0.998	2054	tags=30%, list=11%, signal=33%
20	BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2	Details ...	22	-0.78	-1.48	0.023	0.391	0.999	2304	tags=36%, list=12%, signal=41%
21	INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I)		13	-0.86	-1.48	0.014	0.373	0.999	1678	tags=31%, list=9%, signal=34%
22	INOH_BMP2 SIGNALING PATHWAY(THROUGH SMAD)		10	-0.91	-1.47	0.009	0.432	1.000	579	tags=20%, list=3%, signal=21%
23	NCI_FOXO FAMILY SIGNALING		43	-0.68	-1.47	0.020	0.431	1.000	2054	tags=42%, list=11%, signal=47%
24	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		22	-0.77	-1.46	0.038	0.431	1.000	1947	tags=41%, list=10%, signal=46%
25	BIOCARTA_BONE REMODELING		15	-0.81	-1.45	0.042	0.501	1.000	2054	tags=47%, list=11%, signal=52%
26	NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE		67	-0.62	-1.44	0.021	0.488	1.000	2706	tags=31%, list=15%, signal=37%
27	REACTOME_PI3K_AKT_SIGNALLING		12	-0.85	-1.44	0.049	0.511	1.000	1692	tags=42%, list=9%, signal=46%
28	INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4		13	-0.86	-1.43	0.024	0.512	1.000	1678	tags=31%, list=9%, signal=34%
29	NCI_IL23-MEDIATED SIGNALING EVENTS		65	-0.62	-1.43	0.032	0.505	1.000	2001	tags=26%, list=11%, signal=29%
30	NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING		258	-0.52	-1.43	0.003	0.501	1.000	2135	tags=27%, list=11%, signal=30%
31	NCI_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION		10	-0.86	-1.42	0.072	0.527	1.000	2010	tags=40%, list=11%, signal=45%
32	NCI_TGF-BETA RECEPTOR SIGNALING		258	-0.52	-1.42	0.000	0.521	1.000	2135	tags=27%, list=11%, signal=30%
33	NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING		258	-0.52	-1.42	0.004	0.506	1.000	2135	tags=27%, list=11%, signal=30%
34	INOH_JNK CASCADE		16	-0.80	-1.42	0.054	0.495	1.000	2463	tags=38%, list=13%, signal=43%
35	REACTOME_TCR_SIGNALING		32	-0.68	-1.41	0.069	0.526	1.000	2539	tags=63%, list=14%, signal=72%
36	BIOCARTA_MAPKINASE SIGNALING PATHWAY		54	-0.63	-1.41	0.037	0.516	1.000	2705	tags=44%, list=15%, signal=52%
37	BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE		13	-0.82	-1.40	0.034	0.512	1.000	2548	tags=46%, list=14%, signal=53%
38	NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA		34	-0.67	-1.40	0.050	0.521	1.000	2326	tags=44%, list=12%, signal=50%
39	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING		17	-0.76	-1.39	0.086	0.542	1.000	3064	tags=59%, list=16%, signal=70%
40	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS		13	-0.81	-1.39	0.077	0.535	1.000	1947	tags=54%, list=10%, signal=60%
41	NCI_AURORA A SIGNALING		58	-0.60	-1.39	0.043	0.530	1.000	2001	tags=33%, list=11%, signal=37%
42	NCI_P75(NTR)-MEDIATED SIGNALING		157	-0.54	-1.39	0.009	0.524	1.000	1784	tags=24%, list=10%, signal=27%
43	NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY		80	-0.57	-1.39	0.037	0.524	1.000	2477	tags=31%, list=13%, signal=36%
44	NCI_IL1-MEDIATED SIGNALING EVENTS		187	-0.52	-1.38	0.010	0.524	1.000	2135	tags=27%, list=11%, signal=30%
45	NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT)		48	-0.63	-1.37	0.048	0.559	1.000	1689	tags=27%, list=9%, signal=30%
46	NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION		14	-0.78	-1.37	0.080	0.555	1.000	2255	tags=43%, list=12%, signal=49%
47	NCI_IFN-GAMMA PATHWAY		331	-0.49	-1.37	0.000	0.556	1.000	2135	tags=26%, list=11%, signal=29%
48	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS		11	-0.82	-1.37	0.079	0.545	1.000	772	tags=18%, list=4%, signal=19%
49	NCI_LPA RECEPTOR MEDIATED EVENTS		91	-0.55	-1.36	0.017	0.562	1.000	2001	tags=24%, list=11%, signal=27%
50	NCI_TNF RECEPTOR SIGNALING PATHWAY		244	-0.50	-1.36	0.000	0.552	1.000	2135	tags=28%, list=11%, signal=31%
51	NCI_ENDOTHELINS		147	-0.53	-1.36	0.023	0.543	1.000	2719	tags=27%, list=15%, signal=31%
52	REACTOME_DEATH_RECEPTOR__SIGNALLING		11	-0.82	-1.36	0.102	0.551	1.000	772	tags=18%, list=4%, signal=19%
53	NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS		56	-0.59	-1.35	0.055	0.558	1.000	2248	tags=27%, list=12%, signal=30%
54	REACTOME_CD28_CO_STIMULATION		12	-0.78	-1.35	0.119	0.548	1.000	914	tags=25%, list=5%, signal=26%
55	BIOCARTA_PDGF SIGNALING PATHWAY		24	-0.71	-1.35	0.093	0.544	1.000	2074	tags=33%, list=11%, signal=37%
56	NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES		78	-0.57	-1.35	0.037	0.538	1.000	2121	tags=29%, list=11%, signal=33%
57	BIOCARTA_CERAMIDE SIGNALING PATHWAY		48	-0.61	-1.35	0.069	0.530	1.000	2293	tags=44%, list=12%, signal=50%
58	CELLMAP_ID		11	-0.82	-1.35	0.104	0.526	1.000	1789	tags=36%, list=10%, signal=40%
59	NCI_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		26	-0.68	-1.35	0.093	0.527	1.000	1885	tags=27%, list=10%, signal=30%
60	BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS		16	-0.78	-1.35	0.074	0.526	1.000	1829	tags=44%, list=10%, signal=48%
61	REACTOME_SIGNALLING_BY_NGF		61	-0.58	-1.34	0.037	0.525	1.000	3143	tags=38%, list=17%, signal=45%
62	NCI_GLYPICAN PATHWAY		416	-0.47	-1.34	0.000	0.546	1.000	2074	tags=24%, list=11%, signal=26%
63	BIOCARTA_B CELL SURVIVAL PATHWAY		12	-0.80	-1.34	0.096	0.540	1.000	1996	tags=33%, list=11%, signal=37%
64	NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING		266	-0.49	-1.33	0.004	0.540	1.000	2135	tags=25%, list=11%, signal=28%
65	NCI_GLYPICAN 1 NETWORK		380	-0.47	-1.33	0.000	0.538	1.000	2135	tags=25%, list=11%, signal=28%
66	NCI_IL2 SIGNALING EVENTS MEDIATED BY PI3K		67	-0.57	-1.33	0.051	0.532	1.000	2001	tags=27%, list=11%, signal=30%
67	REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING		20	-0.71	-1.33	0.110	0.539	1.000	1968	tags=35%, list=11%, signal=39%
68	NETPATH_TCR		105	-0.54	-1.33	0.035	0.533	1.000	1643	tags=30%, list=9%, signal=32%
69	NCI_ANDROGEN-MEDIATED SIGNALING		101	-0.53	-1.33	0.032	0.525	1.000	2525	tags=29%, list=14%, signal=33%
70	BIOCARTA_AKT SIGNALING PATHWAY		15	-0.73	-1.32	0.136	0.538	1.000	1784	tags=33%, list=10%, signal=37%
71	NCI_E-CADHERIN SIGNALING IN THE NASCENT ADHERENS JUNCTION		37	-0.62	-1.31	0.089	0.587	1.000	987	tags=24%, list=5%, signal=26%
72	REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE		35	-0.63	-1.30	0.106	0.590	1.000	1692	tags=26%, list=9%, signal=28%
73	INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		18	-0.70	-1.30	0.136	0.598	1.000	2050	tags=44%, list=11%, signal=50%
74	BIOCARTA_AKAP95 ROLE IN MITOSIS AND CHROMOSOME DYNAMICS		11	-0.79	-1.30	0.159	0.598	1.000	1038	tags=45%, list=6%, signal=48%
75	REACTOME_SIGNALING_BY_GPCR		141	-0.50	-1.30	0.032	0.594	1.000	1107	tags=8%, list=6%, signal=8%
76	BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION		17	-0.71	-1.28	0.167	0.647	1.000	1947	tags=47%, list=10%, signal=53%
77	NCI_REGULATION OF P38-ALPHA AND P38-BETA		142	-0.50	-1.28	0.053	0.653	1.000	2135	tags=28%, list=11%, signal=32%
78	NCI_P38 MAPK SIGNALING PATHWAY		162	-0.49	-1.28	0.037	0.648	1.000	2135	tags=27%, list=11%, signal=30%
79	NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5		29	-0.63	-1.27	0.135	0.646	1.000	626	tags=17%, list=3%, signal=18%
80	BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY		15	-0.72	-1.27	0.159	0.642	1.000	2500	tags=40%, list=13%, signal=46%
81	NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES		43	-0.59	-1.27	0.101	0.641	1.000	1431	tags=21%, list=8%, signal=23%
82	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		45	-0.57	-1.27	0.104	0.642	1.000	2248	tags=42%, list=12%, signal=48%
83	REACTOME_G_PROTEIN_MEDIATED_EVENTS		11	-0.77	-1.27	0.156	0.634	1.000	3128	tags=36%, list=17%, signal=44%
84	NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING		88	-0.52	-1.26	0.075	0.640	1.000	1689	tags=23%, list=9%, signal=25%
85	BIOCARTA_RAS SIGNALING PATHWAY		19	-0.69	-1.26	0.167	0.634	1.000	1689	tags=37%, list=9%, signal=40%
86	BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES		25	-0.63	-1.26	0.138	0.636	1.000	2650	tags=36%, list=14%, signal=42%
87	NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY		43	-0.59	-1.26	0.115	0.637	1.000	790	tags=14%, list=4%, signal=15%
88	BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION		17	-0.69	-1.26	0.164	0.630	1.000	1201	tags=29%, list=6%, signal=31%
89	NCI_BMP RECEPTOR SIGNALING		196	-0.47	-1.26	0.034	0.636	1.000	2135	tags=24%, list=11%, signal=27%
90	NETPATH_BCR		115	-0.50	-1.25	0.049	0.632	1.000	2054	tags=30%, list=11%, signal=33%
91	INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE		36	-0.59	-1.25	0.159	0.635	1.000	914	tags=19%, list=5%, signal=20%
92	BIOCARTA_EGF SIGNALING PATHWAY		18	-0.69	-1.25	0.183	0.642	1.000	2074	tags=33%, list=11%, signal=37%
93	NCI_IL12 SIGNALING MEDIATED BY STAT4		28	-0.61	-1.24	0.166	0.648	1.000	579	tags=25%, list=3%, signal=26%
94	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	-0.68	-1.24	0.182	0.645	1.000	377	tags=24%, list=2%, signal=24%
95	BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART		42	-0.57	-1.24	0.159	0.649	1.000	2327	tags=19%, list=12%, signal=22%
96	REACTOME_PLC_BETA_MEDIATED_EVENTS		10	-0.77	-1.24	0.209	0.648	1.000	3128	tags=40%, list=17%, signal=48%
97	BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT		15	-0.70	-1.23	0.229	0.684	1.000	2334	tags=40%, list=13%, signal=46%
98	INOH_B CELL RECEPTOR SIGNALING PATHWAY		68	-0.53	-1.22	0.113	0.702	1.000	2539	tags=29%, list=14%, signal=34%
99	NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY		31	-0.59	-1.22	0.158	0.708	1.000	1689	tags=29%, list=9%, signal=32%
100	BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF		50	-0.55	-1.21	0.163	0.707	1.000	1784	tags=34%, list=10%, signal=38%
101	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR		22	-0.63	-1.21	0.187	0.714	1.000	1692	tags=27%, list=9%, signal=30%
102	NETPATH_EPO		39	-0.57	-1.21	0.178	0.709	1.000	1141	tags=21%, list=6%, signal=22%
103	BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING		31	-0.60	-1.21	0.179	0.703	1.000	2650	tags=29%, list=14%, signal=34%
104	BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION		48	-0.54	-1.21	0.161	0.706	1.000	918	tags=23%, list=5%, signal=24%
105	NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA		56	-0.54	-1.21	0.146	0.701	1.000	1689	tags=25%, list=9%, signal=27%
106	BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION		19	-0.65	-1.20	0.190	0.695	1.000	871	tags=26%, list=5%, signal=28%
107	NCI_CLASS I PI3K SIGNALING EVENTS		217	-0.45	-1.20	0.059	0.703	1.000	2135	tags=25%, list=11%, signal=28%
108	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE		22	-0.63	-1.20	0.220	0.710	1.000	1692	tags=27%, list=9%, signal=30%
109	REACTOME_IRS_RELATED_EVENTS		21	-0.64	-1.20	0.218	0.706	1.000	1692	tags=29%, list=9%, signal=31%
110	NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT		86	-0.49	-1.19	0.149	0.716	1.000	2135	tags=28%, list=11%, signal=31%
111	REACTOME_PI3K_CASCADE		12	-0.70	-1.19	0.272	0.726	1.000	230	tags=17%, list=1%, signal=17%
112	NCI_S1P2 PATHWAY		21	-0.62	-1.18	0.243	0.729	1.000	2650	tags=29%, list=14%, signal=33%
113	REACTOME_IRS_MEDIATED_SIGNALLING		20	-0.64	-1.18	0.235	0.729	1.000	1692	tags=30%, list=9%, signal=33%
114	BIOCARTA_CXCR4 SIGNALING PATHWAY		11	-0.70	-1.17	0.301	0.753	1.000	871	tags=18%, list=5%, signal=19%
115	NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7		21	-0.62	-1.17	0.253	0.750	1.000	1454	tags=19%, list=8%, signal=21%
116	NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY		59	-0.51	-1.17	0.160	0.758	1.000	2010	tags=27%, list=11%, signal=30%
117	REACTOME_MITOTIC_PROMETAPHASE		38	-0.55	-1.17	0.211	0.756	1.000	2420	tags=26%, list=13%, signal=30%
118	REACTOME_SIGNALING_BY_EGFR		27	-0.58	-1.17	0.211	0.751	1.000	1783	tags=22%, list=10%, signal=25%
119	NCI_TRAIL SIGNALING PATHWAY		275	-0.42	-1.16	0.094	0.754	1.000	2135	tags=24%, list=11%, signal=27%
120	BIOCARTA_ATTENUATION OF GPCR SIGNALING		11	-0.68	-1.16	0.303	0.752	1.000	871	tags=27%, list=5%, signal=29%
121	CELLMAP_HEDGEHOG		14	-0.67	-1.16	0.296	0.749	1.000	1598	tags=29%, list=9%, signal=31%
122	BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY		17	-0.65	-1.16	0.271	0.747	1.000	140	tags=12%, list=1%, signal=12%
123	REACTOME_M_PHASE		40	-0.55	-1.16	0.235	0.750	1.000	2420	tags=25%, list=13%, signal=29%
124	REACTOME_APOPTOTIC_EXECUTION__PHASE		30	-0.56	-1.15	0.237	0.751	1.000	2278	tags=27%, list=12%, signal=30%
125	REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_		93	-0.47	-1.15	0.161	0.763	1.000	420	tags=5%, list=2%, signal=5%
126	NCI_MTOR SIGNALING PATHWAY		24	-0.58	-1.15	0.245	0.759	1.000	2719	tags=33%, list=15%, signal=39%
127	NCI_CIRCADIAN RHYTHM PATHWAY		11	-0.69	-1.15	0.336	0.760	1.000	237	tags=18%, list=1%, signal=18%
128	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS		53	-0.51	-1.14	0.222	0.767	1.000	420	tags=8%, list=2%, signal=8%
129	BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING		34	-0.55	-1.14	0.260	0.770	1.000	2001	tags=26%, list=11%, signal=30%
130	BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION		16	-0.64	-1.14	0.308	0.765	1.000	1326	tags=38%, list=7%, signal=40%
131	BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY		13	-0.67	-1.13	0.335	0.777	1.000	1689	tags=31%, list=9%, signal=34%
132	BIOCARTA_THE PRC2 COMPLEX SETS LONG-TERM GENE SILENCING THROUGH MODIFICATION OF HISTONE TAILS		12	-0.66	-1.13	0.314	0.778	1.000	1744	tags=50%, list=9%, signal=55%
133	BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION		16	-0.64	-1.13	0.302	0.773	1.000	1408	tags=25%, list=8%, signal=27%
134	NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY		33	-0.54	-1.13	0.244	0.771	1.000	2705	tags=39%, list=15%, signal=46%
135	CELLMAP_ANDROGENRECEPTOR		70	-0.48	-1.13	0.221	0.768	1.000	2010	tags=33%, list=11%, signal=37%
136	INOH_P38 CASCADE		12	-0.67	-1.13	0.319	0.771	1.000	2485	tags=50%, list=13%, signal=58%
137	REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES		33	-0.54	-1.13	0.282	0.770	1.000	2942	tags=42%, list=16%, signal=50%
138	BIOCARTA_NF-KB SIGNALING PATHWAY		20	-0.60	-1.12	0.317	0.775	1.000	2001	tags=40%, list=11%, signal=45%
139	NCI_OSTEOPONTIN-MEDIATED EVENTS		29	-0.56	-1.12	0.285	0.776	1.000	2054	tags=31%, list=11%, signal=35%
140	BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1		12	-0.67	-1.12	0.325	0.772	1.000	2623	tags=58%, list=14%, signal=68%
141	NETPATH_THROMBOPOIETIN		40	-0.51	-1.12	0.263	0.767	1.000	1141	tags=23%, list=6%, signal=24%
142	BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS		28	-0.57	-1.12	0.307	0.763	1.000	2650	tags=39%, list=14%, signal=46%
143	INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY		132	-0.43	-1.12	0.171	0.760	1.000	2135	tags=23%, list=11%, signal=26%
144	BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS		27	-0.57	-1.12	0.293	0.758	1.000	2074	tags=22%, list=11%, signal=25%
145	NCI_INSULIN PATHWAY		113	-0.44	-1.12	0.185	0.755	1.000	2023	tags=21%, list=11%, signal=24%
146	NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES		21	-0.60	-1.12	0.301	0.754	1.000	1689	tags=29%, list=9%, signal=31%
147	NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA		46	-0.50	-1.12	0.252	0.749	1.000	2135	tags=24%, list=11%, signal=27%
148	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES		16	-0.63	-1.11	0.367	0.747	1.000	2539	tags=63%, list=14%, signal=72%
149	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY		119	-0.44	-1.11	0.211	0.746	1.000	2074	tags=21%, list=11%, signal=23%
150	REACTOME_CENTROSOME_MATURATION		33	-0.54	-1.11	0.284	0.741	1.000	2942	tags=42%, list=16%, signal=50%
151	NCI_ARF6 TRAFFICKING EVENTS		113	-0.44	-1.11	0.206	0.742	1.000	2023	tags=21%, list=11%, signal=24%
152	BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES		38	-0.52	-1.11	0.277	0.738	1.000	2670	tags=37%, list=14%, signal=43%
153	NCI_ARF6 SIGNALING EVENTS		113	-0.44	-1.11	0.206	0.736	1.000	2023	tags=21%, list=11%, signal=24%
154	BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME		10	-0.67	-1.11	0.365	0.733	1.000	267	tags=20%, list=1%, signal=20%
155	NCI_BCR SIGNALING PATHWAY		64	-0.48	-1.11	0.262	0.730	1.000	2054	tags=28%, list=11%, signal=32%
156	BIOCARTA_IGF-1 SIGNALING PATHWAY		19	-0.60	-1.11	0.316	0.730	1.000	2054	tags=21%, list=11%, signal=24%
157	NETPATH_CD40		30	-0.55	-1.11	0.302	0.728	1.000	1784	tags=33%, list=10%, signal=37%
158	NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET)		142	-0.43	-1.10	0.203	0.728	1.000	2074	tags=25%, list=11%, signal=28%
159	BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK)		18	-0.59	-1.10	0.332	0.730	1.000	1598	tags=17%, list=9%, signal=18%
160	CELLMAP_WNT		65	-0.47	-1.10	0.274	0.737	1.000	2627	tags=29%, list=14%, signal=34%
161	REACTOME_PLATELET_ACTIVATION_TRIGGERS		24	-0.56	-1.10	0.325	0.742	1.000	1968	tags=42%, list=11%, signal=47%
162	BIOCARTA_EICOSANOID METABOLISM		19	-0.59	-1.09	0.317	0.740	1.000	1054	tags=16%, list=6%, signal=17%
163	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS		24	-0.56	-1.09	0.326	0.741	1.000	2278	tags=21%, list=12%, signal=24%
164	NETPATH_BDNF		31	-0.55	-1.09	0.327	0.738	1.000	1221	tags=13%, list=7%, signal=14%
165	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL)		31	-0.52	-1.09	0.321	0.736	1.000	1828	tags=29%, list=10%, signal=32%
166	BIOCARTA_P38 MAPK SIGNALING PATHWAY		28	-0.55	-1.09	0.359	0.744	1.000	2525	tags=46%, list=14%, signal=54%
167	NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS		150	-0.42	-1.08	0.247	0.749	1.000	2074	tags=25%, list=11%, signal=28%
168	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		17	-0.58	-1.08	0.375	0.746	1.000	2082	tags=18%, list=11%, signal=20%
169	BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE		26	-0.55	-1.08	0.342	0.744	1.000	2001	tags=42%, list=11%, signal=47%
170	REACTOME_G2_M_TRANSITION		44	-0.50	-1.08	0.318	0.741	1.000	2334	tags=27%, list=13%, signal=31%
171	NCI_IGF1 PATHWAY		124	-0.42	-1.08	0.258	0.737	1.000	2023	tags=21%, list=11%, signal=23%
172	NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2		62	-0.47	-1.08	0.314	0.749	1.000	1887	tags=18%, list=10%, signal=20%
173	BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS		22	-0.56	-1.07	0.396	0.755	1.000	1563	tags=23%, list=8%, signal=25%
174	BIOCARTA_BCR SIGNALING PATHWAY		29	-0.53	-1.07	0.353	0.753	1.000	2054	tags=24%, list=11%, signal=27%
175	BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA		33	-0.52	-1.07	0.354	0.751	1.000	1829	tags=24%, list=10%, signal=27%
176	REACTOME_DOUBLE_STRAND_BREAK_REPAIR		17	-0.58	-1.07	0.365	0.749	1.000	2790	tags=41%, list=15%, signal=48%
177	NETPATH_IL6		57	-0.48	-1.07	0.306	0.744	1.000	1598	tags=30%, list=9%, signal=33%
178	BIOCARTA_ATM SIGNALING PATHWAY		16	-0.60	-1.07	0.371	0.744	1.000	2054	tags=31%, list=11%, signal=35%
179	INOH_SIGNALING WITH WNT (CANONICAL)		55	-0.47	-1.07	0.313	0.745	1.000	2050	tags=20%, list=11%, signal=22%
180	BIOCARTA_ROLE OF RAN IN MITOTIC SPINDLE REGULATION		11	-0.64	-1.07	0.402	0.741	1.000	2272	tags=55%, list=12%, signal=62%
181	NCI_GLYPICAN 3 NETWORK		57	-0.46	-1.06	0.340	0.747	1.000	2463	tags=25%, list=13%, signal=28%
182	BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR		17	-0.59	-1.06	0.370	0.744	1.000	2525	tags=29%, list=14%, signal=34%
183	BIOCARTA_MECHANISMS OF TRANSCRIPTIONAL REPRESSION BY DNA METHYLATION		14	-0.61	-1.06	0.399	0.741	1.000	1967	tags=43%, list=11%, signal=48%
184	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)		16	-0.59	-1.06	0.377	0.739	1.000	2082	tags=19%, list=11%, signal=21%
185	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		28	-0.54	-1.06	0.362	0.737	1.000	1769	tags=18%, list=10%, signal=20%
186	NCI_NECTIN ADHESION PATHWAY		94	-0.43	-1.06	0.305	0.735	1.000	1247	tags=18%, list=7%, signal=19%
187	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)		16	-0.59	-1.06	0.404	0.739	1.000	2082	tags=19%, list=11%, signal=21%
188	NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS		44	-0.49	-1.06	0.343	0.736	1.000	2010	tags=32%, list=11%, signal=36%
189	INOH_T CELL RECEPTOR SIGNALING PATHWAY		51	-0.47	-1.06	0.325	0.733	1.000	2074	tags=27%, list=11%, signal=31%
190	NCI_EPO SIGNALING PATHWAY		32	-0.51	-1.05	0.373	0.734	1.000	1208	tags=22%, list=6%, signal=23%
191	REACTOME_TIE2_SIGNALING		12	-0.62	-1.05	0.430	0.739	1.000	3309	tags=33%, list=18%, signal=41%
192	REACTOME_EGFR_DOWNREGULATION		10	-0.62	-1.05	0.428	0.747	1.000	1783	tags=20%, list=10%, signal=22%
193	INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING)		16	-0.59	-1.05	0.405	0.744	1.000	2082	tags=19%, list=11%, signal=21%
194	BIOCARTA_MTOR SIGNALING PATHWAY		22	-0.55	-1.04	0.412	0.750	1.000	2719	tags=36%, list=15%, signal=43%
195	BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM		14	-0.60	-1.04	0.447	0.750	1.000	496	tags=14%, list=3%, signal=15%
196	NETPATH_IL4		42	-0.47	-1.04	0.350	0.755	1.000	1784	tags=24%, list=10%, signal=26%
197	NCI_A4B1 AND A4B7 INTEGRIN SIGNALING		25	-0.53	-1.04	0.391	0.757	1.000	2525	tags=32%, list=14%, signal=37%
198	NCI_IL6-MEDIATED SIGNALING EVENTS		44	-0.48	-1.03	0.365	0.756	1.000	1326	tags=20%, list=7%, signal=22%
199	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		196	-0.39	-1.03	0.321	0.753	1.000	2135	tags=18%, list=11%, signal=21%
200	BIOCARTA_REGULATION OF PGC-1A		18	-0.56	-1.03	0.431	0.750	1.000	728	tags=11%, list=4%, signal=12%
201	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)		26	-0.52	-1.03	0.405	0.755	1.000	1163	tags=23%, list=6%, signal=25%
202	CELLMAP_NOTCH		45	-0.46	-1.03	0.412	0.753	1.000	1784	tags=36%, list=10%, signal=39%
203	NETPATH_IFN-ALPHA		43	-0.47	-1.03	0.367	0.754	1.000	2074	tags=35%, list=11%, signal=39%
204	NCI_INTEGRINS IN ANGIOGENESIS		63	-0.44	-1.03	0.383	0.753	1.000	1784	tags=19%, list=10%, signal=21%
205	BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR		36	-0.48	-1.02	0.422	0.763	1.000	871	tags=22%, list=5%, signal=23%
206	BIOCARTA_CTCF: FIRST MULTIVALENT NUCLEAR FACTOR		23	-0.53	-1.02	0.414	0.763	1.000	1151	tags=22%, list=6%, signal=23%
207	NCI_S1P3 PATHWAY		24	-0.53	-1.02	0.430	0.760	1.000	971	tags=13%, list=5%, signal=13%
208	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	-0.38	-1.02	0.359	0.757	1.000	2135	tags=18%, list=11%, signal=20%
209	BIOCARTA_INTEGRIN SIGNALING PATHWAY		30	-0.50	-1.02	0.412	0.755	1.000	2054	tags=27%, list=11%, signal=30%
210	NCI_VEGFR1 SPECIFIC SIGNALS		27	-0.51	-1.02	0.438	0.758	1.000	1887	tags=22%, list=10%, signal=25%
211	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE)		19	-0.55	-1.02	0.434	0.757	1.000	2551	tags=42%, list=14%, signal=49%
212	REACTOME_LOSS_OF_PROTEINS_REQUIRED_FOR_INTERPHASE_MICROTUBULE_ORGANIZATION_FROM_THE_CENTROSOME		31	-0.50	-1.02	0.424	0.755	1.000	3243	tags=45%, list=17%, signal=55%
213	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1		11	-0.61	-1.02	0.476	0.752	1.000	935	tags=18%, list=5%, signal=19%
214	NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT		24	-0.53	-1.01	0.426	0.755	1.000	1873	tags=21%, list=10%, signal=23%
215	BIOCARTA_REGULATION OF BAD PHOSPHORYLATION		20	-0.53	-1.01	0.442	0.753	1.000	496	tags=20%, list=3%, signal=21%
216	REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION		21	-0.54	-1.01	0.443	0.761	1.000	2542	tags=33%, list=14%, signal=39%
217	NCI_FGF SIGNALING PATHWAY		43	-0.46	-1.01	0.421	0.762	1.000	1167	tags=14%, list=6%, signal=15%
218	INOH_SIGNALING WITH WNT (MAMMAL)		52	-0.45	-1.01	0.430	0.760	1.000	2050	tags=17%, list=11%, signal=19%
219	BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY		32	-0.49	-1.00	0.463	0.762	1.000	2001	tags=22%, list=11%, signal=24%
220	BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY		34	-0.49	-1.00	0.422	0.761	1.000	2551	tags=47%, list=14%, signal=54%
221	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR		12	-0.57	-1.00	0.487	0.763	1.000	2790	tags=50%, list=15%, signal=59%
222	BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY		11	-0.61	-1.00	0.497	0.762	1.000	496	tags=18%, list=3%, signal=19%
223	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_ALPHA__PPARALPHA_		11	-0.61	-1.00	0.466	0.759	1.000	3260	tags=36%, list=18%, signal=44%
224	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL)		28	-0.50	-1.00	0.457	0.760	1.000	1828	tags=25%, list=10%, signal=28%
225	BIOCARTA_TRKA RECEPTOR SIGNALING PATHWAY		11	-0.60	-1.00	0.503	0.759	1.000	230	tags=9%, list=1%, signal=9%
226	INOH_TGF-BETA_SUPER_FAMILY_SIGNALING_PATHWAY(CANONICAL)		79	-0.41	-1.00	0.428	0.758	1.000	1678	tags=18%, list=9%, signal=19%
227	NCI_REGULATION OF TELOMERASE		58	-0.43	-1.00	0.434	0.755	1.000	1967	tags=21%, list=11%, signal=23%
228	BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC		22	-0.52	-0.99	0.478	0.765	1.000	2074	tags=27%, list=11%, signal=31%
229	NCI_CASPASE CASCADE IN APOPTOSIS		44	-0.46	-0.99	0.460	0.766	1.000	1290	tags=20%, list=7%, signal=22%
230	NCI_S1P4 PATHWAY		11	-0.58	-0.99	0.501	0.768	1.000	971	tags=18%, list=5%, signal=19%
231	INOH_SIGNALING WITHOUT WNT (CANONICAL)		27	-0.50	-0.98	0.442	0.773	1.000	2304	tags=41%, list=12%, signal=46%
232	REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS		20	-0.53	-0.98	0.492	0.771	1.000	2272	tags=25%, list=12%, signal=28%
233	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	-0.57	-0.98	0.478	0.772	1.000	1136	tags=38%, list=6%, signal=41%
234	REACTOME_STEROID_METABOLISM		36	-0.47	-0.98	0.470	0.784	1.000	1041	tags=11%, list=6%, signal=12%
235	BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R		34	-0.47	-0.97	0.469	0.790	1.000	2537	tags=38%, list=14%, signal=44%
236	BIOCARTA_TNFR1 SIGNALING PATHWAY		16	-0.54	-0.97	0.520	0.795	1.000	1048	tags=25%, list=6%, signal=26%
237	NCI_EPHA FORWARD SIGNALING		30	-0.47	-0.97	0.489	0.792	1.000	3015	tags=33%, list=16%, signal=40%
238	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		48	-0.44	-0.97	0.513	0.794	1.000	2074	tags=25%, list=11%, signal=28%
239	INOH_NEGATIVE FEEDBACK REGULATION OF TGF BETA SUPERFAMILY SIGNALING PATHWAY BY R-SMAD DAGRADATION		40	-0.45	-0.96	0.484	0.795	1.000	1221	tags=18%, list=7%, signal=19%
240	INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G)		11	-0.58	-0.96	0.533	0.797	1.000	951	tags=36%, list=5%, signal=38%
241	NCI_CERAMIDE SIGNALING PATHWAY		41	-0.45	-0.96	0.532	0.794	1.000	2278	tags=29%, list=12%, signal=33%
242	CELLMAP_ALPHA6BETA4INTEGRIN		48	-0.43	-0.96	0.530	0.794	1.000	1692	tags=17%, list=9%, signal=18%
243	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS		12	-0.57	-0.96	0.521	0.794	1.000	2790	tags=50%, list=15%, signal=59%
244	CELLMAP_TNF ALPHA/NF-KB		155	-0.36	-0.96	0.582	0.801	1.000	1811	tags=25%, list=10%, signal=28%
245	NETPATH_IL5		31	-0.47	-0.95	0.536	0.803	1.000	1689	tags=29%, list=9%, signal=32%
246	NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR		19	-0.52	-0.95	0.507	0.803	1.000	527	tags=5%, list=3%, signal=5%
247	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		32	-0.46	-0.95	0.524	0.802	1.000	543	tags=16%, list=3%, signal=16%
248	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS		18	-0.51	-0.94	0.538	0.819	1.000	463	tags=17%, list=2%, signal=17%
249	NETPATH_IL-7		16	-0.53	-0.94	0.540	0.824	1.000	626	tags=25%, list=3%, signal=26%
250	BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY		32	-0.46	-0.94	0.526	0.822	1.000	2054	tags=22%, list=11%, signal=25%
251	CELLMAP_EGFR1		117	-0.37	-0.94	0.621	0.821	1.000	2082	tags=31%, list=11%, signal=34%
252	BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES		23	-0.49	-0.94	0.547	0.820	1.000	1689	tags=22%, list=9%, signal=24%
253	INOH_SIGNALING WITHOUT WNT (MAMMAL)		24	-0.48	-0.93	0.527	0.833	1.000	2304	tags=38%, list=12%, signal=43%
254	REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS		18	-0.51	-0.93	0.572	0.831	1.000	463	tags=17%, list=2%, signal=17%
255	BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL		11	-0.55	-0.93	0.575	0.838	1.000	2525	tags=55%, list=14%, signal=63%
256	REACTOME_G2_M_CHECKPOINTS		30	-0.46	-0.93	0.573	0.837	1.000	1111	tags=17%, list=6%, signal=18%
257	BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML		10	-0.57	-0.92	0.574	0.838	1.000	2330	tags=50%, list=13%, signal=57%
258	BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS		25	-0.47	-0.92	0.558	0.835	1.000	1947	tags=36%, list=10%, signal=40%
259	REACTOME_REV_MEDIATED_NUCLEAR_EXPORT_OF_HIV_1_RNA		19	-0.49	-0.92	0.556	0.832	1.000	2272	tags=21%, list=12%, signal=24%
260	BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY		29	-0.45	-0.92	0.578	0.833	1.000	1563	tags=24%, list=8%, signal=26%
261	BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY		11	-0.56	-0.92	0.581	0.832	1.000	594	tags=27%, list=3%, signal=28%
262	REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL		21	-0.49	-0.92	0.575	0.829	1.000	463	tags=14%, list=2%, signal=15%
263	NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING		37	-0.44	-0.92	0.542	0.827	1.000	2650	tags=27%, list=14%, signal=31%
264	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE		13	-0.53	-0.92	0.567	0.826	1.000	1692	tags=31%, list=9%, signal=34%
265	HUMANCYC_CHOLESTEROL BIOSYNTHESIS I		12	-0.55	-0.92	0.591	0.828	1.000	2734	tags=50%, list=15%, signal=59%
266	NCI_ATYPICAL NF-KAPPAB PATHWAY		14	-0.52	-0.92	0.589	0.826	1.000	2001	tags=36%, list=11%, signal=40%
267	NCI_REGULATION OF RETINOBLASTOMA PROTEIN		58	-0.40	-0.91	0.592	0.832	1.000	1789	tags=26%, list=10%, signal=29%
268	NCI_AMB2 INTEGRIN SIGNALING		48	-0.41	-0.91	0.620	0.838	1.000	2086	tags=19%, list=11%, signal=21%
269	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		32	-0.44	-0.91	0.602	0.840	1.000	1887	tags=25%, list=10%, signal=28%
270	NCI_CANONICAL WNT SIGNALING PATHWAY		49	-0.41	-0.91	0.620	0.839	1.000	2463	tags=24%, list=13%, signal=28%
271	HUMANCYC_CHOLESTEROL BIOSYNTHESIS III (VIA DESMOSTEROL)		12	-0.55	-0.91	0.605	0.839	1.000	2734	tags=50%, list=15%, signal=59%
272	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN		12	-0.53	-0.91	0.607	0.838	1.000	2857	tags=17%, list=15%, signal=20%
273	HUMANCYC_CHOLESTEROL BIOSYNTHESIS II (VIA 24,25-DIHYDROLANOSTEROL)		12	-0.55	-0.91	0.615	0.835	1.000	2734	tags=50%, list=15%, signal=59%
274	NCI_S1P1 PATHWAY		64	-0.38	-0.91	0.650	0.832	1.000	1557	tags=14%, list=8%, signal=15%
275	NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS		47	-0.41	-0.90	0.610	0.830	1.000	1454	tags=19%, list=8%, signal=21%
276	NETPATH_IL3		64	-0.39	-0.90	0.650	0.830	1.000	2369	tags=28%, list=13%, signal=32%
277	NETPATH_IL9		11	-0.54	-0.90	0.604	0.829	1.000	1426	tags=27%, list=8%, signal=30%
278	NETPATH_IL2		61	-0.39	-0.90	0.632	0.830	1.000	1947	tags=25%, list=10%, signal=27%
279	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		24	-0.46	-0.90	0.608	0.829	1.000	1769	tags=33%, list=10%, signal=37%
280	CELLMAP_TGFBR		107	-0.36	-0.90	0.746	0.827	1.000	2599	tags=36%, list=14%, signal=41%
281	BIOCARTA_FAS SIGNALING PATHWAY (CD95)		19	-0.48	-0.89	0.621	0.840	1.000	2465	tags=53%, list=13%, signal=61%
282	BIOCARTA_VEGF HYPOXIA AND ANGIOGENESIS		28	-0.45	-0.89	0.598	0.840	1.000	230	tags=4%, list=1%, signal=4%
283	BIOCARTA_ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE PKA		25	-0.46	-0.89	0.656	0.840	1.000	871	tags=16%, list=5%, signal=17%
284	NCI_IL27-MEDIATED SIGNALING EVENTS		26	-0.44	-0.89	0.645	0.842	1.000	1059	tags=19%, list=6%, signal=20%
285	REACTOME_SHC_RELATED_EVENTS		10	-0.55	-0.89	0.639	0.840	1.000	3309	tags=60%, list=18%, signal=73%
286	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		68	-0.38	-0.89	0.684	0.841	1.000	1454	tags=16%, list=8%, signal=17%
287	REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING		11	-0.54	-0.89	0.619	0.841	1.000	3309	tags=55%, list=18%, signal=66%
288	NCI_WNT SIGNALING		49	-0.41	-0.88	0.637	0.838	1.000	2463	tags=24%, list=13%, signal=28%
289	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	-0.47	-0.88	0.645	0.843	1.000	1887	tags=23%, list=10%, signal=25%
290	REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX		22	-0.47	-0.88	0.632	0.841	1.000	2542	tags=32%, list=14%, signal=37%
291	NCI_ARF6 DOWNSTREAM PATHWAY		25	-0.44	-0.88	0.625	0.840	1.000	2023	tags=32%, list=11%, signal=36%
292	BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS		25	-0.45	-0.88	0.663	0.844	1.000	1208	tags=16%, list=6%, signal=17%
293	REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING		10	-0.53	-0.87	0.641	0.852	1.000	3143	tags=50%, list=17%, signal=60%
294	BIOCARTA_PRION PATHWAY		16	-0.49	-0.87	0.646	0.850	1.000	676	tags=13%, list=4%, signal=13%
295	INOH_SNON DEGRADATION SIGNALING		25	-0.44	-0.87	0.667	0.851	1.000	240	tags=12%, list=1%, signal=12%
296	BIOCARTA_TELOMERES TELOMERASE CELLULAR AGING AND IMMORTALITY		15	-0.50	-0.87	0.648	0.854	1.000	1458	tags=20%, list=8%, signal=22%
297	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION		10	-0.53	-0.87	0.657	0.853	1.000	538	tags=40%, list=3%, signal=41%
298	BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES		29	-0.42	-0.86	0.679	0.861	1.000	3309	tags=28%, list=18%, signal=33%
299	INOH_GENE EXPRESSION OF SMAD7 BY R-SMAD:SMAD4		35	-0.41	-0.86	0.690	0.860	1.000	1221	tags=17%, list=7%, signal=18%
300	REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE		11	-0.52	-0.86	0.649	0.863	1.000	944	tags=36%, list=5%, signal=38%
301	INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR)		14	-0.49	-0.86	0.655	0.863	1.000	1689	tags=14%, list=9%, signal=16%
302	BIOCARTA_STATHMIN AND BREAST CANCER RESISTANCE TO ANTIMICROTUBULE AGENTS		19	-0.46	-0.86	0.659	0.863	1.000	1421	tags=26%, list=8%, signal=28%
303	BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS		16	-0.47	-0.86	0.692	0.860	1.000	2525	tags=38%, list=14%, signal=43%
304	REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM		12	-0.50	-0.85	0.670	0.860	1.000	2153	tags=42%, list=12%, signal=47%
305	BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION		28	-0.43	-0.85	0.707	0.858	1.000	2001	tags=32%, list=11%, signal=36%
306	INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY		10	-0.53	-0.85	0.675	0.856	1.000	2054	tags=30%, list=11%, signal=34%
307	BIOCARTA_PROTEASOME COMPLEX		22	-0.45	-0.85	0.668	0.860	1.000	1011	tags=14%, list=5%, signal=14%
308	BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY		19	-0.45	-0.85	0.703	0.862	1.000	1196	tags=16%, list=6%, signal=17%
309	INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING)		30	-0.41	-0.85	0.741	0.860	1.000	1059	tags=20%, list=6%, signal=21%
310	REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION		11	-0.51	-0.85	0.677	0.858	1.000	1227	tags=18%, list=7%, signal=19%
311	BIOCARTA_CHREBP REGULATION BY CARBOHYDRATES AND CAMP		34	-0.41	-0.84	0.736	0.872	1.000	871	tags=12%, list=5%, signal=12%
312	BIOCARTA_WNT SIGNALING PATHWAY		28	-0.41	-0.84	0.729	0.872	1.000	2583	tags=29%, list=14%, signal=33%
313	NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1		17	-0.46	-0.84	0.689	0.870	1.000	2525	tags=41%, list=14%, signal=48%
314	BIOCARTA_ESTROGEN RESPONSIVE PROTEIN EFP CONTROLS CELL CYCLE AND BREAST TUMORS GROWTH		13	-0.49	-0.84	0.705	0.868	1.000	1789	tags=31%, list=10%, signal=34%
315	INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER		30	-0.41	-0.84	0.737	0.867	1.000	1059	tags=20%, list=6%, signal=21%
316	INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL)		22	-0.45	-0.84	0.694	0.865	1.000	1828	tags=36%, list=10%, signal=40%
317	INOH_PLC BETA SIGNALING		18	-0.46	-0.83	0.715	0.868	1.000	122	tags=6%, list=1%, signal=6%
318	BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS		19	-0.45	-0.83	0.714	0.872	1.000	971	tags=26%, list=5%, signal=28%
319	INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE)		20	-0.44	-0.83	0.706	0.870	1.000	2551	tags=40%, list=14%, signal=46%
320	NCI_VISUAL SIGNAL TRANSDUCTION: RODS		19	-0.44	-0.82	0.706	0.882	1.000	2827	tags=16%, list=15%, signal=19%
321	BIOCARTA_TPO SIGNALING PATHWAY		22	-0.43	-0.82	0.738	0.884	1.000	1689	tags=18%, list=9%, signal=20%
322	REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS		26	-0.42	-0.82	0.725	0.885	1.000	1789	tags=19%, list=10%, signal=21%
323	HUMANCYC_SUPERPATHWAY OF CHOLESTEROL BIOSYNTHESIS		23	-0.42	-0.81	0.756	0.890	1.000	1902	tags=26%, list=10%, signal=29%
324	NCI_IL4-MEDIATED SIGNALING EVENTS		58	-0.36	-0.81	0.851	0.893	1.000	1335	tags=14%, list=7%, signal=15%
325	NCI_SIGNALING EVENTS MEDIATED BY PRL		21	-0.43	-0.81	0.781	0.900	1.000	1789	tags=33%, list=10%, signal=37%
326	NETPATH_TIE1_TEK		24	-0.41	-0.80	0.774	0.903	1.000	1454	tags=13%, list=8%, signal=14%
327	REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POLYMERASE_IN_TC_NER		13	-0.46	-0.80	0.724	0.902	1.000	944	tags=31%, list=5%, signal=32%
328	REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND		12	-0.47	-0.80	0.719	0.899	1.000	944	tags=33%, list=5%, signal=35%
329	BIOCARTA_CYCLINS AND CELL CYCLE REGULATION		22	-0.42	-0.80	0.798	0.901	1.000	1201	tags=27%, list=6%, signal=29%
330	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL		25	-0.41	-0.80	0.795	0.902	1.000	1889	tags=36%, list=10%, signal=40%
331	REACTOME_REPAIR_SYNTHESIS_OF_PATCH__27_30_BASES_LONG__BY_DNA_POLYMERASE		13	-0.46	-0.79	0.741	0.918	1.000	944	tags=31%, list=5%, signal=32%
332	REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION		17	-0.43	-0.78	0.792	0.926	1.000	2671	tags=41%, list=14%, signal=48%
333	REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S		14	-0.44	-0.78	0.745	0.927	1.000	2503	tags=29%, list=13%, signal=33%
334	REACTOME_SIGNALING_BY_PDGF		21	-0.42	-0.78	0.819	0.926	1.000	3290	tags=43%, list=18%, signal=52%
335	NETPATH_FLK2_FLT3		16	-0.44	-0.77	0.807	0.931	1.000	1141	tags=19%, list=6%, signal=20%
336	BIOCARTA_MECHANISM OF PROTEIN IMPORT INTO THE NUCLEUS		11	-0.47	-0.77	0.785	0.933	1.000	2272	tags=36%, list=12%, signal=41%
337	BIOCARTA_SEGMENTATION CLOCK		22	-0.41	-0.77	0.838	0.930	1.000	2304	tags=23%, list=12%, signal=26%
338	BIOCARTA_IL-7 SIGNAL TRANSDUCTION		14	-0.44	-0.77	0.798	0.931	1.000	2857	tags=43%, list=15%, signal=51%
339	NCI_A6B1 AND A6B4 INTEGRIN SIGNALING		43	-0.35	-0.76	0.938	0.930	1.000	1681	tags=12%, list=9%, signal=13%
340	BIOCARTA_NUCLEAR RECEPTORS COORDINATE THE ACTIVITIES OF CHROMATIN REMODELING COMPLEXES AND COACTIVATORS TO FACILITATE INITIATION OF TRANSCRIPTION IN CARCINOMA CELLS		14	-0.43	-0.76	0.797	0.927	1.000	2136	tags=29%, list=11%, signal=32%
341	NETPATH_GDNF		29	-0.38	-0.75	0.866	0.940	1.000	3309	tags=28%, list=18%, signal=33%
342	REACTOME_PEROXISOMAL_LIPID_METABOLISM		12	-0.45	-0.75	0.806	0.938	1.000	2116	tags=17%, list=11%, signal=19%
343	NCI_PDGFR-BETA SIGNALING PATHWAY		51	-0.33	-0.74	0.955	0.953	1.000	1947	tags=18%, list=10%, signal=20%
344	INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL)		19	-0.40	-0.73	0.860	0.959	1.000	1828	tags=32%, list=10%, signal=35%
345	BIOCARTA_APOPTOTIC DNA-FRAGMENTATION AND TISSUE HOMEOSTASIS		11	-0.44	-0.73	0.842	0.958	1.000	620	tags=18%, list=3%, signal=19%
346	REACTOME_HIV_LIFE_CYCLE		72	-0.31	-0.73	0.997	0.962	1.000	2815	tags=25%, list=15%, signal=29%
347	REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_TC_NER		14	-0.42	-0.72	0.845	0.963	1.000	944	tags=29%, list=5%, signal=30%
348	REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER		14	-0.42	-0.72	0.820	0.964	1.000	944	tags=29%, list=5%, signal=30%
349	BIOCARTA_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION		12	-0.43	-0.72	0.859	0.962	1.000	2010	tags=25%, list=11%, signal=28%
350	BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD		13	-0.42	-0.72	0.855	0.962	1.000	1454	tags=15%, list=8%, signal=17%
351	INOH_IL-1_SIGNALING(THROUGH_JNK_CASCADE)(CANONICAL)		24	-0.36	-0.71	0.917	0.968	1.000	2537	tags=29%, list=14%, signal=34%
352	REACTOME_TELOMERE_MAINTENANCE		22	-0.37	-0.71	0.904	0.968	1.000	944	tags=23%, list=5%, signal=24%
353	REACTOME_EXTENSION_OF_TELOMERES		19	-0.38	-0.70	0.926	0.971	1.000	944	tags=21%, list=5%, signal=22%
354	BIOCARTA_ADP-RIBOSYLATION FACTOR		18	-0.38	-0.70	0.928	0.971	1.000	2492	tags=33%, list=13%, signal=38%
355	REACTOME_OPIOID_SIGNALLING		22	-0.37	-0.70	0.928	0.969	1.000	2294	tags=23%, list=12%, signal=26%
356	BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY		27	-0.35	-0.70	0.934	0.967	1.000	2650	tags=22%, list=14%, signal=26%
357	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		27	-0.35	-0.70	0.928	0.966	1.000	579	tags=7%, list=3%, signal=8%
358	REACTOME_LAGGING_STRAND_SYNTHESIS		16	-0.39	-0.69	0.884	0.971	1.000	944	tags=25%, list=5%, signal=26%
359	REACTOME_CHOLESTEROL_BIOSYNTHESIS		15	-0.39	-0.68	0.925	0.971	1.000	1041	tags=20%, list=6%, signal=21%
360	BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES		15	-0.38	-0.68	0.909	0.971	1.000	3143	tags=33%, list=17%, signal=40%
361	REACTOME_TELOMERE_C_STRAND__LAGGING_STRAND__SYNTHESIS		18	-0.38	-0.68	0.940	0.968	1.000	944	tags=22%, list=5%, signal=23%
362	BIOCARTA_IL 4 SIGNALING PATHWAY		11	-0.40	-0.68	0.899	0.967	1.000	626	tags=18%, list=3%, signal=19%
363	BIOCARTA_CELL TO CELL ADHESION SIGNALING		10	-0.40	-0.65	0.900	0.979	1.000	797	tags=10%, list=4%, signal=10%
364	NCI_BARD1 SIGNALING EVENTS		26	-0.33	-0.65	0.969	0.978	1.000	3306	tags=35%, list=18%, signal=42%
365	BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS		15	-0.36	-0.65	0.936	0.976	1.000	1689	tags=13%, list=9%, signal=15%
366	REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS		17	-0.34	-0.63	0.950	0.981	1.000	2259	tags=24%, list=12%, signal=27%
367	BIOCARTA_EUKARYOTIC PROTEIN TRANSLATION		10	-0.38	-0.61	0.936	0.988	1.000	1651	tags=30%, list=9%, signal=33%
368	NCI_CELLULAR ROLES OF ANTHRAX TOXIN		15	-0.33	-0.59	0.969	0.990	1.000	3143	tags=27%, list=17%, signal=32%
369	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION		11	-0.34	-0.56	0.963	0.992	1.000	357	tags=9%, list=2%, signal=9%
370	INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING		36	-0.26	-0.54	1.000	0.993	1.000	2624	tags=8%, list=14%, signal=10%