| GS follow link to MSigDB | GS DETAILS | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | RANK AT MAX | LEADING EDGE | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS AND ENTNER-DOUDOROFF | Details ... | 22 | -0.60 | -1.97 | 0.002 | 0.128 | 0.162 | 3439 | tags=55%, list=18%, signal=67% |
| 2 | HUMANCYC_GLYCOLYSIS I | Details ... | 20 | -0.62 | -1.97 | 0.000 | 0.066 | 0.166 | 1758 | tags=45%, list=9%, signal=50% |
| 3 | HUMANCYC_GLYCOLYSIS III | Details ... | 21 | -0.60 | -1.96 | 0.002 | 0.055 | 0.207 | 1758 | tags=43%, list=9%, signal=47% |
| 4 | HUMANCYC_GLYCOLYSIS V | Details ... | 18 | -0.62 | -1.95 | 0.000 | 0.044 | 0.218 | 3439 | tags=56%, list=18%, signal=68% |
| 5 | HUMANCYC_GLUCONEOGENESIS | Details ... | 17 | -0.60 | -1.89 | 0.000 | 0.071 | 0.397 | 3439 | tags=47%, list=18%, signal=58% |
| 6 | HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION | Details ... | 22 | -0.56 | -1.88 | 0.000 | 0.069 | 0.452 | 1758 | tags=41%, list=9%, signal=45% |
| 7 | REACTOME_MUSCLE_CONTRACTION | Details ... | 25 | -0.53 | -1.78 | 0.004 | 0.160 | 0.801 | 4543 | tags=52%, list=24%, signal=69% |
| 8 | REACTOME_GLUCONEOGENESIS | Details ... | 11 | -0.67 | -1.76 | 0.004 | 0.166 | 0.856 | 2347 | tags=55%, list=13%, signal=62% |
| 9 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Details ... | 25 | -0.50 | -1.74 | 0.012 | 0.189 | 0.915 | 4026 | tags=40%, list=22%, signal=51% |
| 10 | HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS | Details ... | 11 | -0.63 | -1.70 | 0.012 | 0.247 | 0.976 | 1206 | tags=36%, list=6%, signal=39% |
| 11 | HUMANCYC_COLANIC ACID BUILDING BLOCKS BIOSYNTHESIS | Details ... | 10 | -0.62 | -1.67 | 0.010 | 0.282 | 0.994 | 2628 | tags=50%, list=14%, signal=58% |
| 12 | HUMANCYC_GLUTATHIONE-MEDIATED DETOXIFICATION | Details ... | 16 | -0.54 | -1.61 | 0.033 | 0.421 | 1.000 | 6470 | tags=69%, list=35%, signal=105% |
| 13 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Details ... | 14 | -0.56 | -1.61 | 0.025 | 0.391 | 1.000 | 4359 | tags=50%, list=23%, signal=65% |
| 14 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III | Details ... | 30 | -0.44 | -1.58 | 0.014 | 0.440 | 1.000 | 4036 | tags=50%, list=22%, signal=64% |
| 15 | BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS | Details ... | 10 | -0.61 | -1.57 | 0.031 | 0.456 | 1.000 | 3304 | tags=50%, list=18%, signal=61% |
| 16 | BIOCARTA_IL 4 SIGNALING PATHWAY | Details ... | 11 | -0.58 | -1.56 | 0.043 | 0.449 | 1.000 | 5196 | tags=64%, list=28%, signal=88% |
| 17 | BIOCARTA_CLASSICAL COMPLEMENT PATHWAY | Details ... | 10 | -0.59 | -1.54 | 0.042 | 0.497 | 1.000 | 3006 | tags=50%, list=16%, signal=60% |
| 18 | HUMANCYC_SERINE-ISOCITRATE LYASE PATHWAY | Details ... | 16 | -0.50 | -1.52 | 0.046 | 0.521 | 1.000 | 1882 | tags=31%, list=10%, signal=35% |
| 19 | REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT | Details ... | 10 | -0.59 | -1.52 | 0.037 | 0.499 | 1.000 | 3006 | tags=50%, list=16%, signal=60% |
| 20 | NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS | Details ... | 13 | -0.53 | -1.52 | 0.059 | 0.490 | 1.000 | 1530 | tags=38%, list=8%, signal=42% |
| 21 | BIOCARTA_IL 2 SIGNALING PATHWAY | 14 | -0.53 | -1.51 | 0.053 | 0.481 | 1.000 | 5389 | tags=64%, list=29%, signal=90% | |
| 22 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 12 | -0.54 | -1.48 | 0.067 | 0.575 | 1.000 | 4543 | tags=58%, list=24%, signal=77% | |
| 23 | INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING | 36 | -0.39 | -1.47 | 0.049 | 0.578 | 1.000 | 5324 | tags=47%, list=29%, signal=66% | |
| 24 | NETPATH_BCR | 115 | -0.30 | -1.46 | 0.018 | 0.588 | 1.000 | 2731 | tags=31%, list=15%, signal=36% | |
| 25 | BIOCARTA_OXIDATIVE STRESS INDUCED GENE EXPRESSION VIA NRF2 | 16 | -0.48 | -1.44 | 0.087 | 0.644 | 1.000 | 2181 | tags=38%, list=12%, signal=42% | |
| 26 | BIOCARTA_DOWNREGULATED OF MTA-3 IN ER-NEGATIVE BREAST TUMORS | 18 | -0.46 | -1.43 | 0.074 | 0.654 | 1.000 | 1803 | tags=39%, list=10%, signal=43% | |
| 27 | REACTOME_PHASE_II_CONJUGATION | 17 | -0.47 | -1.42 | 0.091 | 0.651 | 1.000 | 3522 | tags=41%, list=19%, signal=51% | |
| 28 | REACTOME_COMPLEMENT_CASCADE | 14 | -0.49 | -1.41 | 0.082 | 0.676 | 1.000 | 3006 | tags=36%, list=16%, signal=43% | |
| 29 | BIOCARTA_PLATELET AMYLOID PRECURSOR PROTEIN PATHWAY | 13 | -0.49 | -1.40 | 0.093 | 0.686 | 1.000 | 4803 | tags=54%, list=26%, signal=73% | |
| 30 | BIOCARTA_EPO SIGNALING PATHWAY | 11 | -0.51 | -1.39 | 0.111 | 0.703 | 1.000 | 5531 | tags=73%, list=30%, signal=103% | |
| 31 | NCI_ALPHA-SYNUCLEIN SIGNALING | 32 | -0.38 | -1.39 | 0.071 | 0.688 | 1.000 | 2337 | tags=28%, list=13%, signal=32% | |
| 32 | BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE | 14 | -0.48 | -1.39 | 0.097 | 0.675 | 1.000 | 1282 | tags=29%, list=7%, signal=31% | |
| 33 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | 12 | -0.50 | -1.38 | 0.112 | 0.679 | 1.000 | 5781 | tags=58%, list=31%, signal=85% | |
| 34 | BIOCARTA_STRESS INDUCTION OF HSP REGULATION | 14 | -0.48 | -1.37 | 0.091 | 0.687 | 1.000 | 2184 | tags=36%, list=12%, signal=40% | |
| 35 | REACTOME_CELL_JUNCTION_ORGANIZATION | 23 | -0.41 | -1.37 | 0.095 | 0.692 | 1.000 | 2633 | tags=39%, list=14%, signal=46% | |
| 36 | INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 17 | -0.44 | -1.36 | 0.101 | 0.701 | 1.000 | 4927 | tags=47%, list=26%, signal=64% | |
| 37 | NCI_S1P2 PATHWAY | 21 | -0.42 | -1.36 | 0.095 | 0.686 | 1.000 | 1222 | tags=24%, list=7%, signal=25% | |
| 38 | REACTOME_SEMAPHORIN_INTERACTIONS | 30 | -0.38 | -1.36 | 0.091 | 0.675 | 1.000 | 2149 | tags=33%, list=12%, signal=38% | |
| 39 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR__IGF__ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS__IGFBPS_ | 12 | -0.49 | -1.35 | 0.118 | 0.677 | 1.000 | 7658 | tags=75%, list=41%, signal=127% | |
| 40 | NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR | 19 | -0.43 | -1.34 | 0.106 | 0.709 | 1.000 | 4057 | tags=42%, list=22%, signal=54% | |
| 41 | BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS | 19 | -0.42 | -1.33 | 0.113 | 0.704 | 1.000 | 66 | tags=16%, list=0%, signal=16% | |
| 42 | BIOCARTA_IL-7 SIGNAL TRANSDUCTION | 14 | -0.47 | -1.33 | 0.124 | 0.691 | 1.000 | 5389 | tags=50%, list=29%, signal=70% | |
| 43 | HUMANCYC_ENTNER-DOUDOROFF PATHWAY II (NON-PHOSPHORYLATIVE) | 12 | -0.49 | -1.33 | 0.120 | 0.693 | 1.000 | 4607 | tags=42%, list=25%, signal=55% | |
| 44 | BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY | 12 | -0.48 | -1.33 | 0.119 | 0.691 | 1.000 | 2240 | tags=42%, list=12%, signal=47% | |
| 45 | BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE | 18 | -0.43 | -1.32 | 0.148 | 0.704 | 1.000 | 1698 | tags=28%, list=9%, signal=31% | |
| 46 | BIOCARTA_G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS | 10 | -0.49 | -1.29 | 0.181 | 0.801 | 1.000 | 3304 | tags=40%, list=18%, signal=49% | |
| 47 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I | 10 | -0.49 | -1.29 | 0.191 | 0.786 | 1.000 | 2281 | tags=30%, list=12%, signal=34% | |
| 48 | BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD | 13 | -0.45 | -1.28 | 0.168 | 0.783 | 1.000 | 3916 | tags=54%, list=21%, signal=68% | |
| 49 | NCI_VISUAL SIGNAL TRANSDUCTION: CONES | 18 | -0.41 | -1.28 | 0.159 | 0.768 | 1.000 | 3491 | tags=39%, list=19%, signal=48% | |
| 50 | REACTOME_ATP_FORMATION | 15 | -0.43 | -1.26 | 0.175 | 0.826 | 1.000 | 1220 | tags=20%, list=7%, signal=21% | |
| 51 | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS | 39 | -0.33 | -1.26 | 0.135 | 0.827 | 1.000 | 1758 | tags=23%, list=9%, signal=25% | |
| 52 | BIOCARTA_CHREBP REGULATION BY CARBOHYDRATES AND CAMP | 34 | -0.34 | -1.26 | 0.143 | 0.813 | 1.000 | 2114 | tags=26%, list=11%, signal=30% | |
| 53 | INOH_CANONICAL NOTCH SIGNALING PATHWAY | 26 | -0.35 | -1.26 | 0.163 | 0.805 | 1.000 | 1907 | tags=27%, list=10%, signal=30% | |
| 54 | REACTOME_BIOLOGICAL_OXIDATIONS | 46 | -0.32 | -1.26 | 0.137 | 0.793 | 1.000 | 4012 | tags=30%, list=22%, signal=39% | |
| 55 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II | 22 | -0.38 | -1.26 | 0.166 | 0.779 | 1.000 | 1206 | tags=23%, list=6%, signal=24% | |
| 56 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | 19 | -0.39 | -1.25 | 0.165 | 0.788 | 1.000 | 1882 | tags=21%, list=10%, signal=23% | |
| 57 | NCI_IL4-MEDIATED SIGNALING EVENTS | 58 | -0.30 | -1.25 | 0.135 | 0.776 | 1.000 | 5531 | tags=48%, list=30%, signal=68% | |
| 58 | BIOCARTA_IL 3 SIGNALING PATHWAY | 11 | -0.46 | -1.25 | 0.185 | 0.769 | 1.000 | 6265 | tags=73%, list=34%, signal=110% | |
| 59 | REACTOME_SPHINGOLIPID_METABOLISM | 10 | -0.48 | -1.24 | 0.221 | 0.792 | 1.000 | 4981 | tags=50%, list=27%, signal=68% | |
| 60 | NETPATH_GDNF | 29 | -0.34 | -1.23 | 0.165 | 0.804 | 1.000 | 2287 | tags=28%, list=12%, signal=31% | |
| 61 | REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS | 19 | -0.39 | -1.23 | 0.181 | 0.792 | 1.000 | 1882 | tags=21%, list=10%, signal=23% | |
| 62 | BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION | 13 | -0.43 | -1.23 | 0.178 | 0.780 | 1.000 | 2240 | tags=31%, list=12%, signal=35% | |
| 63 | NCI_THROMBOXANE A2 RECEPTOR SIGNALING | 50 | -0.30 | -1.23 | 0.126 | 0.775 | 1.000 | 1698 | tags=20%, list=9%, signal=22% | |
| 64 | CELLMAP_KITRECEPTOR | 49 | -0.30 | -1.23 | 0.145 | 0.778 | 1.000 | 3166 | tags=29%, list=17%, signal=34% | |
| 65 | BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION | 26 | -0.35 | -1.22 | 0.201 | 0.779 | 1.000 | 4419 | tags=31%, list=24%, signal=40% | |
| 66 | HUMANCYC_ISOLEUCINE DEGRADATION III | 13 | -0.42 | -1.22 | 0.208 | 0.782 | 1.000 | 3551 | tags=38%, list=19%, signal=47% | |
| 67 | INOH_DROSOPHILA WINGLESS/WNT SIGNALING PATHWAY | 13 | -0.43 | -1.22 | 0.217 | 0.772 | 1.000 | 4779 | tags=54%, list=26%, signal=72% | |
| 68 | INOH_NOTCH SECRETORY PATHWAY | 26 | -0.35 | -1.21 | 0.205 | 0.789 | 1.000 | 1907 | tags=27%, list=10%, signal=30% | |
| 69 | INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 16 | -0.40 | -1.21 | 0.200 | 0.781 | 1.000 | 6963 | tags=63%, list=37%, signal=100% | |
| 70 | NCI_SIGNALING EVENTS MEDIATED BY PTP1B | 46 | -0.31 | -1.21 | 0.167 | 0.775 | 1.000 | 5811 | tags=43%, list=31%, signal=63% | |
| 71 | INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING) | 16 | -0.40 | -1.21 | 0.212 | 0.766 | 1.000 | 6963 | tags=63%, list=37%, signal=100% | |
| 72 | BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT | 15 | -0.41 | -1.20 | 0.226 | 0.769 | 1.000 | 1073 | tags=20%, list=6%, signal=21% | |
| 73 | INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING) | 16 | -0.40 | -1.20 | 0.233 | 0.771 | 1.000 | 6963 | tags=63%, list=37%, signal=100% | |
| 74 | NCI_LPA4-MEDIATED SIGNALING EVENTS | 12 | -0.43 | -1.19 | 0.232 | 0.781 | 1.000 | 4369 | tags=58%, list=23%, signal=76% | |
| 75 | NCI_S1P3 PATHWAY | 24 | -0.36 | -1.19 | 0.234 | 0.776 | 1.000 | 1222 | tags=21%, list=7%, signal=22% | |
| 76 | BIOCARTA_VISUAL SIGNAL TRANSDUCTION | 13 | -0.41 | -1.19 | 0.239 | 0.770 | 1.000 | 5555 | tags=38%, list=30%, signal=55% | |
| 77 | BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY | 11 | -0.43 | -1.19 | 0.240 | 0.773 | 1.000 | 5418 | tags=45%, list=29%, signal=64% | |
| 78 | INOH_WNT SECRETORY PATHWAY (MAMMAL) | 48 | -0.30 | -1.18 | 0.184 | 0.776 | 1.000 | 4779 | tags=31%, list=26%, signal=42% | |
| 79 | INOH_PLC BETA SIGNALING | 18 | -0.38 | -1.18 | 0.237 | 0.768 | 1.000 | 863 | tags=22%, list=5%, signal=23% | |
| 80 | HUMANCYC_SALVAGE PATHWAYS OF PURINE AND PYRIMIDINE NUCLEOTIDES | 19 | -0.37 | -1.18 | 0.255 | 0.775 | 1.000 | 5414 | tags=53%, list=29%, signal=74% | |
| 81 | INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING | 11 | -0.44 | -1.17 | 0.256 | 0.776 | 1.000 | 5068 | tags=64%, list=27%, signal=87% | |
| 82 | NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1 | 17 | -0.39 | -1.17 | 0.246 | 0.790 | 1.000 | 4687 | tags=53%, list=25%, signal=71% | |
| 83 | REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | 20 | -0.36 | -1.17 | 0.260 | 0.786 | 1.000 | 1368 | tags=25%, list=7%, signal=27% | |
| 84 | REACTOME_METABOLISM_OF_CARBOHYDRATES | 70 | -0.27 | -1.17 | 0.193 | 0.778 | 1.000 | 2649 | tags=27%, list=14%, signal=32% | |
| 85 | REACTOME_CD28_CO_STIMULATION | 12 | -0.43 | -1.16 | 0.275 | 0.783 | 1.000 | 1598 | tags=25%, list=9%, signal=27% | |
| 86 | REACTOME_EGFR_DOWNREGULATION | 10 | -0.45 | -1.16 | 0.285 | 0.778 | 1.000 | 4400 | tags=50%, list=24%, signal=65% | |
| 87 | BIOCARTA_ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM | 41 | -0.30 | -1.16 | 0.246 | 0.771 | 1.000 | 3304 | tags=22%, list=18%, signal=27% | |
| 88 | BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS | 15 | -0.39 | -1.15 | 0.288 | 0.785 | 1.000 | 2240 | tags=27%, list=12%, signal=30% | |
| 89 | REACTOME_PHASE_1_FUNCTIONALIZATION | 10 | -0.44 | -1.15 | 0.297 | 0.777 | 1.000 | 5601 | tags=50%, list=30%, signal=71% | |
| 90 | BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY | 17 | -0.38 | -1.15 | 0.283 | 0.781 | 1.000 | 6753 | tags=59%, list=36%, signal=92% | |
| 91 | CELLMAP_NOTCH | 45 | -0.29 | -1.15 | 0.234 | 0.778 | 1.000 | 1420 | tags=22%, list=8%, signal=24% | |
| 92 | NCI_IGF1 PATHWAY | 124 | -0.24 | -1.15 | 0.186 | 0.774 | 1.000 | 2240 | tags=21%, list=12%, signal=24% | |
| 93 | REACTOME_AXON_GUIDANCE | 56 | -0.28 | -1.14 | 0.242 | 0.769 | 1.000 | 1710 | tags=23%, list=9%, signal=25% | |
| 94 | HUMANCYC_GLYCINE BETAINE DEGRADATION | 10 | -0.43 | -1.14 | 0.301 | 0.769 | 1.000 | 1882 | tags=20%, list=10%, signal=22% | |
| 95 | REACTOME_SIGNALING_BY_GPCR | 141 | -0.23 | -1.14 | 0.198 | 0.762 | 1.000 | 6064 | tags=40%, list=33%, signal=58% | |
| 96 | REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 15 | -0.38 | -1.13 | 0.275 | 0.778 | 1.000 | 2240 | tags=33%, list=12%, signal=38% | |
| 97 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | 12 | -0.42 | -1.13 | 0.286 | 0.774 | 1.000 | 1763 | tags=42%, list=9%, signal=46% | |
| 98 | HUMANCYC_TRIACYLGLYCEROL DEGRADATION | 12 | -0.41 | -1.13 | 0.285 | 0.770 | 1.000 | 5763 | tags=50%, list=31%, signal=72% | |
| 99 | HUMANCYC_PURINE NUCLEOTIDES DE NOVO BIOSYNTHESIS I | 25 | -0.34 | -1.13 | 0.275 | 0.773 | 1.000 | 3319 | tags=36%, list=18%, signal=44% | |
| 100 | BIOCARTA_EICOSANOID METABOLISM | 19 | -0.36 | -1.13 | 0.286 | 0.769 | 1.000 | 4722 | tags=42%, list=25%, signal=56% | |
| 101 | NCI_ENDOTHELINS | 147 | -0.23 | -1.13 | 0.187 | 0.761 | 1.000 | 2451 | tags=20%, list=13%, signal=23% | |
| 102 | HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS | 33 | -0.31 | -1.13 | 0.302 | 0.754 | 1.000 | 3319 | tags=36%, list=18%, signal=44% | |
| 103 | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING | 32 | -0.31 | -1.13 | 0.274 | 0.750 | 1.000 | 2240 | tags=22%, list=12%, signal=25% | |
| 104 | REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_ | 93 | -0.24 | -1.12 | 0.224 | 0.762 | 1.000 | 6063 | tags=42%, list=33%, signal=62% | |
| 105 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 12 | -0.41 | -1.12 | 0.310 | 0.758 | 1.000 | 1710 | tags=42%, list=9%, signal=46% | |
| 106 | NCI_A6B1 AND A6B4 INTEGRIN SIGNALING | 43 | -0.29 | -1.12 | 0.287 | 0.755 | 1.000 | 4761 | tags=37%, list=26%, signal=50% | |
| 107 | INOH_WNT SECRETORY PATHWAY (CANONICAL) | 47 | -0.28 | -1.12 | 0.274 | 0.748 | 1.000 | 4779 | tags=30%, list=26%, signal=40% | |
| 108 | HUMANCYC_SALVAGE PATHWAYS OF PYRIMIDINE RIBONUCLEOTIDES | 12 | -0.40 | -1.11 | 0.324 | 0.749 | 1.000 | 5414 | tags=42%, list=29%, signal=59% | |
| 109 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY | 31 | -0.31 | -1.11 | 0.298 | 0.747 | 1.000 | 2727 | tags=29%, list=15%, signal=34% | |
| 110 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | 12 | -0.41 | -1.11 | 0.333 | 0.743 | 1.000 | 1220 | tags=17%, list=7%, signal=18% | |
| 111 | REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | 15 | -0.37 | -1.11 | 0.341 | 0.745 | 1.000 | 1763 | tags=33%, list=9%, signal=37% | |
| 112 | BIOCARTA_PHOSPHOINOSITIDES AND THEIR DOWNSTREAM TARGETS | 21 | -0.34 | -1.10 | 0.298 | 0.753 | 1.000 | 3434 | tags=33%, list=18%, signal=41% | |
| 113 | INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING | 193 | -0.21 | -1.10 | 0.230 | 0.747 | 1.000 | 1674 | tags=15%, list=9%, signal=16% | |
| 114 | HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES | 11 | -0.41 | -1.10 | 0.351 | 0.741 | 1.000 | 3131 | tags=45%, list=17%, signal=55% | |
| 115 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 12 | -0.40 | -1.10 | 0.319 | 0.759 | 1.000 | 7402 | tags=67%, list=40%, signal=111% | |
| 116 | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY | 132 | -0.22 | -1.09 | 0.260 | 0.762 | 1.000 | 1674 | tags=16%, list=9%, signal=17% | |
| 117 | NCI_IL12 SIGNALING MEDIATED BY STAT4 | 28 | -0.32 | -1.09 | 0.303 | 0.759 | 1.000 | 1129 | tags=18%, list=6%, signal=19% | |
| 118 | INOH_ERK CASCADE | 12 | -0.40 | -1.09 | 0.353 | 0.753 | 1.000 | 863 | tags=25%, list=5%, signal=26% | |
| 119 | BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY | 32 | -0.30 | -1.09 | 0.319 | 0.749 | 1.000 | 3166 | tags=28%, list=17%, signal=34% | |
| 120 | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) | 48 | -0.27 | -1.09 | 0.319 | 0.744 | 1.000 | 3166 | tags=27%, list=17%, signal=33% | |
| 121 | NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS | 229 | -0.21 | -1.09 | 0.251 | 0.752 | 1.000 | 1722 | tags=16%, list=9%, signal=17% | |
| 122 | BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES | 28 | -0.31 | -1.08 | 0.327 | 0.755 | 1.000 | 2081 | tags=21%, list=11%, signal=24% | |
| 123 | BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY | 24 | -0.33 | -1.08 | 0.317 | 0.751 | 1.000 | 4543 | tags=42%, list=24%, signal=55% | |
| 124 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 15 | -0.37 | -1.08 | 0.358 | 0.750 | 1.000 | 1763 | tags=33%, list=9%, signal=37% | |
| 125 | REACTOME_HEMOSTASIS | 147 | -0.22 | -1.07 | 0.311 | 0.780 | 1.000 | 4660 | tags=33%, list=25%, signal=43% | |
| 126 | NCI_A4B1 AND A4B7 INTEGRIN SIGNALING | 25 | -0.31 | -1.07 | 0.339 | 0.777 | 1.000 | 4779 | tags=44%, list=26%, signal=59% | |
| 127 | NCI_ARF6 TRAFFICKING EVENTS | 113 | -0.22 | -1.07 | 0.318 | 0.771 | 1.000 | 1204 | tags=15%, list=6%, signal=16% | |
| 128 | REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION | 47 | -0.27 | -1.07 | 0.361 | 0.765 | 1.000 | 3789 | tags=26%, list=20%, signal=32% | |
| 129 | BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION | 10 | -0.41 | -1.06 | 0.379 | 0.771 | 1.000 | 1530 | tags=30%, list=8%, signal=33% | |
| 130 | NCI_ARF6 SIGNALING EVENTS | 113 | -0.22 | -1.06 | 0.336 | 0.775 | 1.000 | 1204 | tags=15%, list=6%, signal=16% | |
| 131 | INOH_NOTCH SECRETORY PATHWAY (MAMMAL) | 22 | -0.32 | -1.06 | 0.382 | 0.770 | 1.000 | 1907 | tags=27%, list=10%, signal=30% | |
| 132 | NCI_INSULIN PATHWAY | 113 | -0.22 | -1.06 | 0.330 | 0.765 | 1.000 | 1204 | tags=15%, list=6%, signal=16% | |
| 133 | INOH_MAMMALIAN NOTCH SIGNALING PATHWAY | 22 | -0.32 | -1.06 | 0.367 | 0.763 | 1.000 | 1907 | tags=27%, list=10%, signal=30% | |
| 134 | REACTOME_METABOLISM_OF_NUCLEOTIDES | 62 | -0.25 | -1.05 | 0.364 | 0.766 | 1.000 | 3409 | tags=27%, list=18%, signal=33% | |
| 135 | NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING | 44 | -0.26 | -1.05 | 0.363 | 0.763 | 1.000 | 3819 | tags=34%, list=21%, signal=43% | |
| 136 | BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION | 25 | -0.31 | -1.05 | 0.395 | 0.781 | 1.000 | 2081 | tags=20%, list=11%, signal=22% | |
| 137 | NCI_FGF SIGNALING PATHWAY | 43 | -0.27 | -1.04 | 0.392 | 0.779 | 1.000 | 1030 | tags=14%, list=6%, signal=15% | |
| 138 | REACTOME_PEPTIDE_CHAIN_ELONGATION | 45 | -0.26 | -1.04 | 0.361 | 0.774 | 1.000 | 3789 | tags=24%, list=20%, signal=31% | |
| 139 | REACTOME_INORGANIC_CATION_ANION_SLC_TRANSPORTERS | 12 | -0.38 | -1.04 | 0.398 | 0.777 | 1.000 | 1338 | tags=25%, list=7%, signal=27% | |
| 140 | REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | 14 | -0.35 | -1.04 | 0.416 | 0.783 | 1.000 | 5290 | tags=50%, list=28%, signal=70% | |
| 141 | BIOCARTA_IL-10 ANTI-INFLAMMATORY SIGNALING PATHWAY | 13 | -0.37 | -1.03 | 0.402 | 0.797 | 1.000 | 2184 | tags=23%, list=12%, signal=26% | |
| 142 | NETPATH_IL3 | 64 | -0.24 | -1.02 | 0.393 | 0.810 | 1.000 | 3166 | tags=25%, list=17%, signal=30% | |
| 143 | INOH_SIGNALING WITH WNT (XENOPUS) | 16 | -0.34 | -1.02 | 0.434 | 0.816 | 1.000 | 2568 | tags=31%, list=14%, signal=36% | |
| 144 | INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING | 105 | -0.21 | -1.01 | 0.404 | 0.828 | 1.000 | 2298 | tags=18%, list=12%, signal=21% | |
| 145 | BIOCARTA_HEMOGLOBINS CHAPERONE | 10 | -0.40 | -1.01 | 0.448 | 0.840 | 1.000 | 312 | tags=20%, list=2%, signal=20% | |
| 146 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS) | 16 | -0.34 | -1.01 | 0.436 | 0.838 | 1.000 | 2568 | tags=31%, list=14%, signal=36% | |
| 147 | INOH_SIGNALING WITH WNT (MAMMAL) | 52 | -0.25 | -1.00 | 0.437 | 0.850 | 1.000 | 4288 | tags=29%, list=23%, signal=37% | |
| 148 | NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING | 266 | -0.18 | -0.99 | 0.453 | 0.860 | 1.000 | 2451 | tags=18%, list=13%, signal=20% | |
| 149 | BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS | 21 | -0.30 | -0.99 | 0.448 | 0.857 | 1.000 | 2240 | tags=24%, list=12%, signal=27% | |
| 150 | INOH_B CELL RECEPTOR SIGNALING PATHWAY | 68 | -0.23 | -0.99 | 0.483 | 0.862 | 1.000 | 2447 | tags=21%, list=13%, signal=24% | |
| 151 | INOH_INTEGRIN SIGNALING PATHWAY | 92 | -0.22 | -0.98 | 0.495 | 0.882 | 1.000 | 5031 | tags=39%, list=27%, signal=53% | |
| 152 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | 14 | -0.34 | -0.98 | 0.502 | 0.882 | 1.000 | 1048 | tags=14%, list=6%, signal=15% | |
| 153 | HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE DEOXYRIBONUCLEOTIDES | 11 | -0.36 | -0.98 | 0.486 | 0.886 | 1.000 | 2742 | tags=36%, list=15%, signal=43% | |
| 154 | BIOCARTA_CXCR4 SIGNALING PATHWAY | 11 | -0.37 | -0.98 | 0.493 | 0.882 | 1.000 | 2731 | tags=27%, list=15%, signal=32% | |
| 155 | BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME | 10 | -0.37 | -0.97 | 0.501 | 0.877 | 1.000 | 2114 | tags=40%, list=11%, signal=45% | |
| 156 | NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING | 37 | -0.25 | -0.97 | 0.531 | 0.876 | 1.000 | 4402 | tags=32%, list=24%, signal=42% | |
| 157 | REACTOME_CLASS_B_2__SECRETIN_FAMILY_RECEPTORS_ | 23 | -0.29 | -0.97 | 0.489 | 0.884 | 1.000 | 4795 | tags=30%, list=26%, signal=41% | |
| 158 | INOH_MAMMALIAN WNT SIGNALING PATHWAY | 70 | -0.22 | -0.97 | 0.526 | 0.887 | 1.000 | 5743 | tags=37%, list=31%, signal=54% | |
| 159 | BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA | 28 | -0.28 | -0.96 | 0.507 | 0.884 | 1.000 | 5502 | tags=50%, list=30%, signal=71% | |
| 160 | NCI_EPHRIN B REVERSE SIGNALING | 27 | -0.28 | -0.96 | 0.496 | 0.884 | 1.000 | 1530 | tags=19%, list=8%, signal=20% | |
| 161 | NCI_S1P4 PATHWAY | 11 | -0.36 | -0.96 | 0.538 | 0.879 | 1.000 | 1222 | tags=27%, list=7%, signal=29% | |
| 162 | NCI_EPHA FORWARD SIGNALING | 30 | -0.27 | -0.96 | 0.519 | 0.884 | 1.000 | 2992 | tags=23%, list=16%, signal=28% | |
| 163 | REACTOME_LIPOPROTEIN_METABOLISM | 18 | -0.31 | -0.96 | 0.497 | 0.879 | 1.000 | 8471 | tags=56%, list=46%, signal=102% | |
| 164 | CELLMAP_ALPHA6BETA4INTEGRIN | 48 | -0.24 | -0.96 | 0.540 | 0.876 | 1.000 | 2317 | tags=23%, list=12%, signal=26% | |
| 165 | NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES | 43 | -0.25 | -0.96 | 0.506 | 0.873 | 1.000 | 4810 | tags=33%, list=26%, signal=44% | |
| 166 | BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR | 36 | -0.25 | -0.96 | 0.537 | 0.872 | 1.000 | 2081 | tags=19%, list=11%, signal=22% | |
| 167 | BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING | 31 | -0.26 | -0.95 | 0.539 | 0.886 | 1.000 | 2731 | tags=26%, list=15%, signal=30% | |
| 168 | INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY | 196 | -0.18 | -0.94 | 0.620 | 0.899 | 1.000 | 3328 | tags=21%, list=18%, signal=25% | |
| 169 | BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY | 20 | -0.30 | -0.94 | 0.556 | 0.894 | 1.000 | 2240 | tags=25%, list=12%, signal=28% | |
| 170 | REACTOME_REGULATORY_RNA_PATHWAYS | 10 | -0.37 | -0.94 | 0.560 | 0.889 | 1.000 | 6641 | tags=60%, list=36%, signal=93% | |
| 171 | REACTOME_CYTOCHROME_P450___ARRANGED_BY_SUBSTRATE_TYPE | 19 | -0.30 | -0.93 | 0.555 | 0.906 | 1.000 | 5018 | tags=37%, list=27%, signal=50% | |
| 172 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP) | 179 | -0.18 | -0.93 | 0.620 | 0.903 | 1.000 | 5111 | tags=27%, list=27%, signal=37% | |
| 173 | HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION | 30 | -0.26 | -0.93 | 0.580 | 0.898 | 1.000 | 4423 | tags=37%, list=24%, signal=48% | |
| 174 | REACTOME_INSULIN_SYNTHESIS_AND_SECRETION | 66 | -0.22 | -0.93 | 0.594 | 0.895 | 1.000 | 3398 | tags=23%, list=18%, signal=28% | |
| 175 | BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY | 24 | -0.28 | -0.93 | 0.539 | 0.891 | 1.000 | 2731 | tags=25%, list=15%, signal=29% | |
| 176 | INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR) | 14 | -0.33 | -0.93 | 0.557 | 0.897 | 1.000 | 863 | tags=21%, list=5%, signal=22% | |
| 177 | BIOCARTA_PRION PATHWAY | 16 | -0.31 | -0.93 | 0.557 | 0.893 | 1.000 | 225 | tags=13%, list=1%, signal=13% | |
| 178 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN) | 175 | -0.18 | -0.92 | 0.667 | 0.899 | 1.000 | 6391 | tags=35%, list=34%, signal=53% | |
| 179 | REACTOME_PHASE_1___FUNCTIONALIZATION_OF_COMPOUNDS | 29 | -0.26 | -0.92 | 0.563 | 0.900 | 1.000 | 5601 | tags=34%, list=30%, signal=49% | |
| 180 | NCI_P38 MAPK SIGNALING PATHWAY | 162 | -0.18 | -0.92 | 0.656 | 0.895 | 1.000 | 2451 | tags=17%, list=13%, signal=19% | |
| 181 | NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA | 67 | -0.21 | -0.92 | 0.596 | 0.892 | 1.000 | 2317 | tags=18%, list=12%, signal=20% | |
| 182 | REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS | 44 | -0.24 | -0.92 | 0.599 | 0.893 | 1.000 | 3789 | tags=23%, list=20%, signal=28% | |
| 183 | NCI_INTEGRINS IN ANGIOGENESIS | 63 | -0.22 | -0.92 | 0.604 | 0.889 | 1.000 | 2315 | tags=19%, list=12%, signal=22% | |
| 184 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP) | 175 | -0.18 | -0.92 | 0.671 | 0.884 | 1.000 | 6391 | tags=35%, list=34%, signal=53% | |
| 185 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 18 | -0.29 | -0.91 | 0.590 | 0.887 | 1.000 | 2240 | tags=28%, list=12%, signal=32% | |
| 186 | HUMANCYC_PURINE NUCLEOTIDES DE NOVO BIOSYNTHESIS II | 10 | -0.35 | -0.91 | 0.601 | 0.895 | 1.000 | 3319 | tags=40%, list=18%, signal=49% | |
| 187 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE) | 32 | -0.25 | -0.91 | 0.593 | 0.892 | 1.000 | 2731 | tags=25%, list=15%, signal=29% | |
| 188 | REACTOME_VIRAL_MRNA_TRANSLATION | 46 | -0.23 | -0.91 | 0.620 | 0.888 | 1.000 | 3789 | tags=24%, list=20%, signal=30% | |
| 189 | BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY | 29 | -0.26 | -0.91 | 0.598 | 0.885 | 1.000 | 4543 | tags=34%, list=24%, signal=46% | |
| 190 | NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS | 68 | -0.21 | -0.90 | 0.634 | 0.895 | 1.000 | 2731 | tags=19%, list=15%, signal=22% | |
| 191 | REACTOME_PLATELET_DEGRANULATION_ | 42 | -0.23 | -0.90 | 0.624 | 0.899 | 1.000 | 3685 | tags=26%, list=20%, signal=33% | |
| 192 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE) | 185 | -0.17 | -0.90 | 0.742 | 0.895 | 1.000 | 6709 | tags=36%, list=36%, signal=56% | |
| 193 | REACTOME_PURINE_METABOLISM | 39 | -0.23 | -0.90 | 0.617 | 0.894 | 1.000 | 4137 | tags=31%, list=22%, signal=39% | |
| 194 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 18 | -0.29 | -0.89 | 0.615 | 0.895 | 1.000 | 2240 | tags=28%, list=12%, signal=32% | |
| 195 | REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR | 10 | -0.34 | -0.89 | 0.604 | 0.896 | 1.000 | 3604 | tags=40%, list=19%, signal=50% | |
| 196 | BIOCARTA_INTEGRIN SIGNALING PATHWAY | 30 | -0.25 | -0.89 | 0.617 | 0.892 | 1.000 | 5502 | tags=47%, list=30%, signal=66% | |
| 197 | NETPATH_IL2 | 61 | -0.21 | -0.89 | 0.682 | 0.889 | 1.000 | 4561 | tags=33%, list=24%, signal=43% | |
| 198 | NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING | 40 | -0.23 | -0.89 | 0.620 | 0.884 | 1.000 | 3777 | tags=30%, list=20%, signal=38% | |
| 199 | REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES | 64 | -0.21 | -0.89 | 0.678 | 0.880 | 1.000 | 4316 | tags=28%, list=23%, signal=36% | |
| 200 | BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1 | 12 | -0.32 | -0.89 | 0.589 | 0.883 | 1.000 | 856 | tags=17%, list=5%, signal=17% | |
| 201 | NCI_MTOR SIGNALING PATHWAY | 24 | -0.26 | -0.89 | 0.611 | 0.881 | 1.000 | 2207 | tags=25%, list=12%, signal=28% | |
| 202 | REACTOME_FORMATION_OF_PLATELET_PLUG | 81 | -0.20 | -0.89 | 0.708 | 0.880 | 1.000 | 4660 | tags=31%, list=25%, signal=41% | |
| 203 | NCI_VISUAL SIGNAL TRANSDUCTION: RODS | 19 | -0.28 | -0.88 | 0.605 | 0.878 | 1.000 | 7922 | tags=53%, list=43%, signal=92% | |
| 204 | NCI_EPHRINA-EPHA PATHWAY | 40 | -0.23 | -0.88 | 0.628 | 0.880 | 1.000 | 2992 | tags=23%, list=16%, signal=27% | |
| 205 | BIOCARTA_ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE PKA | 25 | -0.26 | -0.88 | 0.652 | 0.882 | 1.000 | 2081 | tags=20%, list=11%, signal=22% | |
| 206 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 22 | -0.26 | -0.88 | 0.657 | 0.879 | 1.000 | 1598 | tags=18%, list=9%, signal=20% | |
| 207 | REACTOME_PLATELET_ACTIVATION | 69 | -0.21 | -0.88 | 0.697 | 0.876 | 1.000 | 4660 | tags=30%, list=25%, signal=40% | |
| 208 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | 56 | -0.21 | -0.88 | 0.690 | 0.872 | 1.000 | 4026 | tags=27%, list=22%, signal=34% | |
| 209 | REACTOME_SIGNALING_IN_IMMUNE_SYSTEM | 136 | -0.18 | -0.87 | 0.781 | 0.878 | 1.000 | 3821 | tags=25%, list=21%, signal=31% | |
| 210 | INOH_XENOPUS AXIS FORMATION WNT SIGNALING PATHWAY | 42 | -0.22 | -0.87 | 0.691 | 0.881 | 1.000 | 2568 | tags=17%, list=14%, signal=19% | |
| 211 | NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7 | 21 | -0.26 | -0.86 | 0.640 | 0.896 | 1.000 | 3093 | tags=29%, list=17%, signal=34% | |
| 212 | NCI_OSTEOPONTIN-MEDIATED EVENTS | 29 | -0.25 | -0.86 | 0.704 | 0.896 | 1.000 | 2080 | tags=21%, list=11%, signal=23% | |
| 213 | NETPATH_IL-7 | 16 | -0.29 | -0.86 | 0.674 | 0.898 | 1.000 | 1530 | tags=19%, list=8%, signal=20% | |
| 214 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__ | 44 | -0.22 | -0.85 | 0.736 | 0.901 | 1.000 | 3685 | tags=25%, list=20%, signal=31% | |
| 215 | INOH_SIGNALING WITH WNT (CANONICAL) | 55 | -0.21 | -0.85 | 0.751 | 0.902 | 1.000 | 4345 | tags=27%, list=23%, signal=35% | |
| 216 | REACTOME_EXOCYTOSIS_OF_ALPHA_GRANULE_ | 40 | -0.22 | -0.84 | 0.735 | 0.916 | 1.000 | 3685 | tags=25%, list=20%, signal=31% | |
| 217 | BIOCARTA_REGULATION OF BAD PHOSPHORYLATION | 20 | -0.26 | -0.84 | 0.668 | 0.914 | 1.000 | 2152 | tags=20%, list=12%, signal=23% | |
| 218 | NETPATH_FLK2_FLT3 | 16 | -0.27 | -0.84 | 0.697 | 0.911 | 1.000 | 2287 | tags=25%, list=12%, signal=28% | |
| 219 | INOH_CANONICAL WNT SIGNALING PATHWAY | 73 | -0.19 | -0.83 | 0.800 | 0.917 | 1.000 | 5743 | tags=36%, list=31%, signal=51% | |
| 220 | REACTOME_STEROID_HORMONES | 13 | -0.29 | -0.83 | 0.705 | 0.918 | 1.000 | 3362 | tags=23%, list=18%, signal=28% | |
| 221 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE) | 197 | -0.16 | -0.83 | 0.886 | 0.915 | 1.000 | 5111 | tags=26%, list=27%, signal=36% | |
| 222 | INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL) | 189 | -0.16 | -0.83 | 0.896 | 0.914 | 1.000 | 5111 | tags=26%, list=27%, signal=36% | |
| 223 | BIOCARTA_CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) AND BETA 2 ADRENERGIC RECEPTOR (B2AR) PATHWAY | 17 | -0.27 | -0.83 | 0.694 | 0.917 | 1.000 | 2081 | tags=24%, list=11%, signal=26% | |
| 224 | INOH_PHOSPHOLIPASE C GAMMA SIGNALING | 48 | -0.20 | -0.83 | 0.770 | 0.913 | 1.000 | 2240 | tags=17%, list=12%, signal=19% | |
| 225 | REACTOME_EUKARYOTIC_TRANSLATION_TERMINATION | 46 | -0.21 | -0.82 | 0.792 | 0.918 | 1.000 | 4634 | tags=26%, list=25%, signal=35% | |
| 226 | BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY | 32 | -0.22 | -0.82 | 0.755 | 0.922 | 1.000 | 1161 | tags=16%, list=6%, signal=17% | |
| 227 | BIOCARTA_FIBRINOLYSIS PATHWAY | 12 | -0.29 | -0.82 | 0.714 | 0.921 | 1.000 | 4667 | tags=50%, list=25%, signal=67% | |
| 228 | REACTOME_COMMON_PATHWAY | 11 | -0.31 | -0.81 | 0.702 | 0.925 | 1.000 | 6890 | tags=55%, list=37%, signal=87% | |
| 229 | BIOCARTA_CARDIAC PROTECTION AGAINST ROS | 11 | -0.30 | -0.81 | 0.695 | 0.929 | 1.000 | 13072 | tags=100%, list=70%, signal=336% | |
| 230 | NCI_EPO SIGNALING PATHWAY | 32 | -0.22 | -0.81 | 0.795 | 0.925 | 1.000 | 4947 | tags=34%, list=27%, signal=47% | |
| 231 | BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY | 15 | -0.27 | -0.79 | 0.770 | 0.941 | 1.000 | 2577 | tags=27%, list=14%, signal=31% | |
| 232 | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | 57 | -0.19 | -0.79 | 0.849 | 0.938 | 1.000 | 4278 | tags=26%, list=23%, signal=34% | |
| 233 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 53 | -0.19 | -0.79 | 0.842 | 0.934 | 1.000 | 5984 | tags=38%, list=32%, signal=55% | |
| 234 | BIOCARTA_RB TUMOR SUPPRESSOR/CHECKPOINT SIGNALING IN RESPONSE TO DNA DAMAGE | 12 | -0.29 | -0.79 | 0.729 | 0.934 | 1.000 | 1820 | tags=17%, list=10%, signal=18% | |
| 235 | HUMANCYC_SUPERPATHWAY OF CITRULLINE METABOLISM | 11 | -0.29 | -0.79 | 0.736 | 0.930 | 1.000 | 2275 | tags=18%, list=12%, signal=21% | |
| 236 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 13 | -0.28 | -0.79 | 0.756 | 0.931 | 1.000 | 4217 | tags=38%, list=23%, signal=50% | |
| 237 | BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA | 33 | -0.21 | -0.79 | 0.804 | 0.933 | 1.000 | 803 | tags=12%, list=4%, signal=13% | |
| 238 | NCI_CIRCADIAN RHYTHM PATHWAY | 11 | -0.29 | -0.78 | 0.756 | 0.940 | 1.000 | 1113 | tags=18%, list=6%, signal=19% | |
| 239 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL) | 28 | -0.22 | -0.78 | 0.812 | 0.938 | 1.000 | 4664 | tags=36%, list=25%, signal=48% | |
| 240 | BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS | 22 | -0.23 | -0.77 | 0.797 | 0.942 | 1.000 | 2114 | tags=18%, list=11%, signal=20% | |
| 241 | BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY | 27 | -0.22 | -0.77 | 0.817 | 0.939 | 1.000 | 1161 | tags=15%, list=6%, signal=16% | |
| 242 | NETPATH_IL4 | 42 | -0.19 | -0.77 | 0.866 | 0.943 | 1.000 | 5531 | tags=40%, list=30%, signal=57% | |
| 243 | REACTOME_OPIOID_SIGNALLING | 22 | -0.23 | -0.77 | 0.833 | 0.941 | 1.000 | 1222 | tags=18%, list=7%, signal=19% | |
| 244 | REACTOME_TAT_MEDIATED_HIV_1_ELONGATION_ARREST_AND_RECOVERY_ | 19 | -0.24 | -0.76 | 0.803 | 0.941 | 1.000 | 5290 | tags=42%, list=28%, signal=59% | |
| 245 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) | 26 | -0.22 | -0.76 | 0.826 | 0.947 | 1.000 | 5959 | tags=42%, list=32%, signal=62% | |
| 246 | INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5) | 10 | -0.28 | -0.75 | 0.789 | 0.944 | 1.000 | 5531 | tags=40%, list=30%, signal=57% | |
| 247 | BIOCARTA_B CELL SURVIVAL PATHWAY | 12 | -0.27 | -0.75 | 0.797 | 0.943 | 1.000 | 2207 | tags=25%, list=12%, signal=28% | |
| 248 | REACTOME_PAUSING_AND_RECOVERY_OF_TAT_MEDIATED_HIV_1_ELONGATION | 19 | -0.24 | -0.75 | 0.790 | 0.939 | 1.000 | 5290 | tags=42%, list=28%, signal=59% | |
| 249 | HUMANCYC_FATTY ACID BETA-OXIDATION II (CORE PATHWAY) | 16 | -0.24 | -0.74 | 0.815 | 0.954 | 1.000 | 3551 | tags=31%, list=19%, signal=39% | |
| 250 | BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION | 17 | -0.24 | -0.74 | 0.805 | 0.955 | 1.000 | 912 | tags=12%, list=5%, signal=12% | |
| 251 | BIOCARTA_SEGMENTATION CLOCK | 22 | -0.22 | -0.72 | 0.870 | 0.969 | 1.000 | 429 | tags=9%, list=2%, signal=9% | |
| 252 | BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY | 13 | -0.24 | -0.70 | 0.852 | 0.988 | 1.000 | 2240 | tags=23%, list=12%, signal=26% | |
| 253 | BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB | 12 | -0.26 | -0.70 | 0.867 | 0.985 | 1.000 | 7321 | tags=58%, list=39%, signal=96% | |
| 254 | NCI_S1P1 PATHWAY | 64 | -0.16 | -0.69 | 0.964 | 0.987 | 1.000 | 2240 | tags=14%, list=12%, signal=16% | |
| 255 | NCI_PDGFR-BETA SIGNALING PATHWAY | 51 | -0.17 | -0.69 | 0.923 | 0.985 | 1.000 | 3166 | tags=18%, list=17%, signal=21% | |
| 256 | NETPATH_TIE1_TEK | 24 | -0.21 | -0.69 | 0.906 | 0.983 | 1.000 | 4947 | tags=38%, list=27%, signal=51% | |
| 257 | REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | 10 | -0.27 | -0.68 | 0.886 | 0.983 | 1.000 | 4959 | tags=40%, list=27%, signal=54% | |
| 258 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | 16 | -0.23 | -0.68 | 0.896 | 0.983 | 1.000 | 7316 | tags=44%, list=39%, signal=72% | |
| 259 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1 | 11 | -0.26 | -0.68 | 0.852 | 0.980 | 1.000 | 5927 | tags=55%, list=32%, signal=80% | |
| 260 | NCI_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT | 26 | -0.19 | -0.67 | 0.923 | 0.984 | 1.000 | 2810 | tags=19%, list=15%, signal=23% | |
| 261 | REACTOME_FORMATION_OF_FIBRIN_CLOT__CLOTTING_CASCADE_ | 28 | -0.19 | -0.66 | 0.924 | 0.985 | 1.000 | 7209 | tags=50%, list=39%, signal=81% | |
| 262 | BIOCARTA_CELL TO CELL ADHESION SIGNALING | 10 | -0.26 | -0.65 | 0.904 | 0.988 | 1.000 | 5132 | tags=40%, list=28%, signal=55% | |
| 263 | BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY | 19 | -0.20 | -0.65 | 0.921 | 0.990 | 1.000 | 1965 | tags=16%, list=11%, signal=18% | |
| 264 | NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT | 24 | -0.19 | -0.64 | 0.945 | 0.988 | 1.000 | 5257 | tags=33%, list=28%, signal=46% | |
| 265 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS | 10 | -0.25 | -0.64 | 0.908 | 0.986 | 1.000 | 519 | tags=10%, list=3%, signal=10% | |
| 266 | BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT | 15 | -0.21 | -0.62 | 0.947 | 0.992 | 1.000 | 184 | tags=7%, list=1%, signal=7% | |
| 267 | REACTOME_RESOLUTION_OF_ABASIC_SITES__AP_SITES_ | 14 | -0.21 | -0.62 | 0.944 | 0.991 | 1.000 | 6263 | tags=50%, list=34%, signal=75% | |
| 268 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY | 12 | -0.22 | -0.62 | 0.934 | 0.987 | 1.000 | 7783 | tags=67%, list=42%, signal=114% | |
| 269 | BIOCARTA_GRANZYME A MEDIATED APOPTOSIS PATHWAY | 12 | -0.22 | -0.61 | 0.931 | 0.987 | 1.000 | 3065 | tags=25%, list=16%, signal=30% | |
| 270 | BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE | 13 | -0.22 | -0.61 | 0.921 | 0.985 | 1.000 | 7321 | tags=54%, list=39%, signal=89% | |
| 271 | REACTOME_BASE_EXCISION_REPAIR | 14 | -0.21 | -0.61 | 0.941 | 0.981 | 1.000 | 6263 | tags=50%, list=34%, signal=75% | |
| 272 | INOH_IKK-NF-KAPPAB CASCADE | 12 | -0.21 | -0.57 | 0.956 | 0.992 | 1.000 | 7867 | tags=58%, list=42%, signal=101% | |
| 273 | NCI_AMB2 INTEGRIN SIGNALING | 48 | -0.14 | -0.55 | 0.992 | 0.995 | 1.000 | 7728 | tags=50%, list=42%, signal=85% | |
| 274 | REACTOME_HORMONE_BIOSYNTHESIS | 31 | -0.15 | -0.55 | 0.994 | 0.992 | 1.000 | 2194 | tags=13%, list=12%, signal=15% | |
| 275 | BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN | 14 | -0.17 | -0.49 | 0.990 | 0.998 | 1.000 | 5536 | tags=36%, list=30%, signal=51% | |
| 276 | REACTOME_REMOVAL_OF_DNA_PATCH_CONTAINING_ABASIC_RESIDUE | 11 | -0.18 | -0.48 | 0.992 | 0.996 | 1.000 | 7783 | tags=64%, list=42%, signal=109% |