| GS follow link to MSigDB | GS DETAILS | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | RANK AT MAX | LEADING EDGE | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 49 | -0.62 | -2.13 | 0.000 | 0.006 | 0.006 | 2639 | tags=37%, list=12%, signal=42% |
| 2 | NETPATH_TCR | Details ... | 109 | -0.52 | -2.05 | 0.000 | 0.011 | 0.024 | 3592 | tags=41%, list=16%, signal=49% |
| 3 | NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 108 | -0.51 | -2.03 | 0.000 | 0.009 | 0.030 | 3644 | tags=36%, list=17%, signal=43% |
| 4 | BIOCARTA_KERATINOCYTE DIFFERENTIATION | Details ... | 50 | -0.59 | -2.02 | 0.000 | 0.011 | 0.046 | 4362 | tags=44%, list=20%, signal=55% |
| 5 | NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA | Details ... | 34 | -0.63 | -1.99 | 0.000 | 0.015 | 0.080 | 3560 | tags=50%, list=16%, signal=60% |
| 6 | INOH_GENE EXPRESSION OF SOCS BY STAT DIMER | Details ... | 13 | -0.73 | -1.89 | 0.004 | 0.051 | 0.276 | 2942 | tags=62%, list=13%, signal=71% |
| 7 | NCI_TNF RECEPTOR SIGNALING PATHWAY | Details ... | 247 | -0.43 | -1.89 | 0.000 | 0.046 | 0.289 | 3166 | tags=26%, list=14%, signal=30% |
| 8 | BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF | Details ... | 51 | -0.55 | -1.87 | 0.000 | 0.051 | 0.355 | 3560 | tags=39%, list=16%, signal=47% |
| 9 | BIOCARTA_TNF/STRESS RELATED SIGNALING | Details ... | 23 | -0.66 | -1.87 | 0.004 | 0.048 | 0.370 | 1725 | tags=35%, list=8%, signal=38% |
| 10 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Details ... | 13 | -0.74 | -1.85 | 0.004 | 0.051 | 0.423 | 2112 | tags=31%, list=10%, signal=34% |
| 11 | NCI_P38 MAPK SIGNALING PATHWAY | Details ... | 164 | -0.44 | -1.83 | 0.000 | 0.061 | 0.524 | 2057 | tags=20%, list=9%, signal=22% |
| 12 | NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS | Details ... | 118 | -0.46 | -1.81 | 0.000 | 0.074 | 0.619 | 3644 | tags=32%, list=17%, signal=38% |
| 13 | BIOCARTA_CASPASE CASCADE IN APOPTOSIS | Details ... | 21 | -0.64 | -1.80 | 0.006 | 0.080 | 0.678 | 3560 | tags=57%, list=16%, signal=68% |
| 14 | NCI_REGULATION OF P38-ALPHA AND P38-BETA | Details ... | 144 | -0.43 | -1.79 | 0.000 | 0.081 | 0.706 | 1939 | tags=19%, list=9%, signal=20% |
| 15 | BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF | Details ... | 17 | -0.67 | -1.79 | 0.004 | 0.078 | 0.712 | 3252 | tags=47%, list=15%, signal=55% |
| 16 | NCI_CASPASE CASCADE IN APOPTOSIS | Details ... | 45 | -0.52 | -1.75 | 0.002 | 0.114 | 0.865 | 2997 | tags=36%, list=14%, signal=41% |
| 17 | REACTOME_G_PROTEIN_MEDIATED_EVENTS | Details ... | 12 | -0.73 | -1.75 | 0.006 | 0.113 | 0.879 | 5222 | tags=67%, list=24%, signal=87% |
| 18 | NETPATH_EPO | Details ... | 37 | -0.54 | -1.73 | 0.002 | 0.124 | 0.915 | 5046 | tags=51%, list=23%, signal=67% |
| 19 | BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS | Details ... | 29 | -0.55 | -1.73 | 0.008 | 0.128 | 0.931 | 2185 | tags=28%, list=10%, signal=31% |
| 20 | NCI_CELLULAR ROLES OF ANTHRAX TOXIN | Details ... | 15 | -0.65 | -1.72 | 0.010 | 0.123 | 0.934 | 2185 | tags=33%, list=10%, signal=37% |
| 21 | REACTOME_PLC_BETA_MEDIATED_EVENTS | 10 | -0.74 | -1.71 | 0.013 | 0.133 | 0.959 | 5222 | tags=70%, list=24%, signal=92% | |
| 22 | BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY | 44 | -0.51 | -1.71 | 0.006 | 0.127 | 0.961 | 4418 | tags=48%, list=20%, signal=60% | |
| 23 | NETPATH_IL4 | 44 | -0.51 | -1.70 | 0.004 | 0.129 | 0.970 | 3731 | tags=36%, list=17%, signal=44% | |
| 24 | NCI_ARF6 DOWNSTREAM PATHWAY | 27 | -0.57 | -1.70 | 0.006 | 0.127 | 0.970 | 4418 | tags=52%, list=20%, signal=65% | |
| 25 | NCI_BMP RECEPTOR SIGNALING | 197 | -0.40 | -1.70 | 0.000 | 0.123 | 0.970 | 2226 | tags=20%, list=10%, signal=22% | |
| 26 | BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS | 15 | -0.64 | -1.70 | 0.016 | 0.119 | 0.970 | 3592 | tags=47%, list=16%, signal=56% | |
| 27 | NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES | 80 | -0.46 | -1.70 | 0.000 | 0.115 | 0.970 | 1939 | tags=20%, list=9%, signal=22% | |
| 28 | BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE | 11 | -0.71 | -1.70 | 0.012 | 0.112 | 0.971 | 2177 | tags=45%, list=10%, signal=50% | |
| 29 | NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES | 43 | -0.51 | -1.69 | 0.004 | 0.112 | 0.973 | 1939 | tags=21%, list=9%, signal=23% | |
| 30 | NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES | 21 | -0.60 | -1.69 | 0.004 | 0.110 | 0.973 | 956 | tags=24%, list=4%, signal=25% | |
| 31 | BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA | 30 | -0.56 | -1.69 | 0.012 | 0.114 | 0.977 | 3858 | tags=47%, list=18%, signal=57% | |
| 32 | BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS | 19 | -0.61 | -1.68 | 0.012 | 0.119 | 0.984 | 3415 | tags=53%, list=16%, signal=62% | |
| 33 | BIOCARTA_BCR SIGNALING PATHWAY | 29 | -0.55 | -1.67 | 0.019 | 0.120 | 0.986 | 1634 | tags=28%, list=7%, signal=30% | |
| 34 | BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY | 26 | -0.57 | -1.67 | 0.009 | 0.119 | 0.988 | 4840 | tags=50%, list=22%, signal=64% | |
| 35 | NCI_IL1-MEDIATED SIGNALING EVENTS | 187 | -0.40 | -1.67 | 0.000 | 0.118 | 0.990 | 1939 | tags=17%, list=9%, signal=19% | |
| 36 | BIOCARTA_TNFR2 SIGNALING PATHWAY | 12 | -0.69 | -1.66 | 0.012 | 0.127 | 0.994 | 3575 | tags=58%, list=16%, signal=70% | |
| 37 | BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY | 13 | -0.65 | -1.65 | 0.024 | 0.138 | 0.995 | 2185 | tags=31%, list=10%, signal=34% | |
| 38 | NCI_FAS SIGNALING PATHWAY (CD95) | 32 | -0.52 | -1.64 | 0.012 | 0.136 | 0.995 | 2385 | tags=28%, list=11%, signal=32% | |
| 39 | NCI_ARF1 PATHWAY | 14 | -0.64 | -1.63 | 0.021 | 0.144 | 0.996 | 5435 | tags=79%, list=25%, signal=104% | |
| 40 | NETPATH_IL3 | 63 | -0.46 | -1.62 | 0.002 | 0.157 | 0.998 | 5351 | tags=48%, list=24%, signal=63% | |
| 41 | NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING | 262 | -0.36 | -1.62 | 0.000 | 0.155 | 0.998 | 4395 | tags=31%, list=20%, signal=38% | |
| 42 | NCI_OSTEOPONTIN-MEDIATED EVENTS | 29 | -0.52 | -1.61 | 0.020 | 0.160 | 0.999 | 5751 | tags=59%, list=26%, signal=79% | |
| 43 | BIOCARTA_CERAMIDE SIGNALING PATHWAY | 49 | -0.46 | -1.60 | 0.011 | 0.171 | 0.999 | 1288 | tags=22%, list=6%, signal=24% | |
| 44 | NCI_GLYPICAN PATHWAY | 419 | -0.35 | -1.60 | 0.000 | 0.168 | 0.999 | 4836 | tags=33%, list=22%, signal=42% | |
| 45 | NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING | 262 | -0.36 | -1.60 | 0.000 | 0.165 | 0.999 | 4395 | tags=31%, list=20%, signal=38% | |
| 46 | NCI_IFN-GAMMA PATHWAY | 334 | -0.35 | -1.60 | 0.000 | 0.169 | 1.000 | 3877 | tags=27%, list=18%, signal=33% | |
| 47 | BIOCARTA_TNFR1 SIGNALING PATHWAY | 17 | -0.59 | -1.59 | 0.035 | 0.169 | 1.000 | 643 | tags=24%, list=3%, signal=24% | |
| 48 | NCI_TGF-BETA RECEPTOR SIGNALING | 262 | -0.36 | -1.59 | 0.000 | 0.167 | 1.000 | 4395 | tags=31%, list=20%, signal=38% | |
| 49 | NCI_IL2-MEDIATED SIGNALING EVENTS | 108 | -0.41 | -1.59 | 0.000 | 0.167 | 1.000 | 3644 | tags=29%, list=17%, signal=34% | |
| 50 | NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 54 | -0.46 | -1.58 | 0.009 | 0.170 | 1.000 | 1288 | tags=19%, list=6%, signal=20% | |
| 51 | BIOCARTA_EICOSANOID METABOLISM | 20 | -0.57 | -1.58 | 0.034 | 0.167 | 1.000 | 3047 | tags=30%, list=14%, signal=35% | |
| 52 | NETPATH_THROMBOPOIETIN | 40 | -0.49 | -1.58 | 0.011 | 0.167 | 1.000 | 3173 | tags=28%, list=14%, signal=32% | |
| 53 | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) | 44 | -0.46 | -1.58 | 0.008 | 0.167 | 1.000 | 5351 | tags=43%, list=24%, signal=57% | |
| 54 | NETPATH_IL-7 | 15 | -0.61 | -1.58 | 0.038 | 0.165 | 1.000 | 2116 | tags=47%, list=10%, signal=52% | |
| 55 | BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES | 25 | -0.53 | -1.58 | 0.025 | 0.162 | 1.000 | 3858 | tags=40%, list=18%, signal=48% | |
| 56 | NCI_TRAIL SIGNALING PATHWAY | 276 | -0.36 | -1.57 | 0.000 | 0.175 | 1.000 | 3644 | tags=27%, list=17%, signal=32% | |
| 57 | INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5) | 10 | -0.67 | -1.56 | 0.024 | 0.180 | 1.000 | 1084 | tags=20%, list=5%, signal=21% | |
| 58 | BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 27 | -0.52 | -1.56 | 0.031 | 0.177 | 1.000 | 1288 | tags=22%, list=6%, signal=24% | |
| 59 | NCI_GLYPICAN 1 NETWORK | 384 | -0.34 | -1.56 | 0.000 | 0.177 | 1.000 | 4836 | tags=33%, list=22%, signal=42% | |
| 60 | BIOCARTA_MAPKINASE SIGNALING PATHWAY | 53 | -0.45 | -1.54 | 0.025 | 0.191 | 1.000 | 2871 | tags=30%, list=13%, signal=35% | |
| 61 | NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING | 278 | -0.35 | -1.54 | 0.002 | 0.194 | 1.000 | 4487 | tags=27%, list=20%, signal=34% | |
| 62 | BIOCARTA_APOPTOTIC DNA-FRAGMENTATION AND TISSUE HOMEOSTASIS | 10 | -0.64 | -1.53 | 0.047 | 0.202 | 1.000 | 989 | tags=40%, list=5%, signal=42% | |
| 63 | BIOCARTA_CELL TO CELL ADHESION SIGNALING | 12 | -0.63 | -1.53 | 0.054 | 0.201 | 1.000 | 3858 | tags=33%, list=18%, signal=40% | |
| 64 | NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS | 13 | -0.60 | -1.53 | 0.044 | 0.199 | 1.000 | 1815 | tags=31%, list=8%, signal=34% | |
| 65 | NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY | 33 | -0.49 | -1.53 | 0.023 | 0.200 | 1.000 | 3644 | tags=27%, list=17%, signal=33% | |
| 66 | NETPATH_IL2 | 58 | -0.43 | -1.52 | 0.025 | 0.212 | 1.000 | 2361 | tags=26%, list=11%, signal=29% | |
| 67 | REACTOME_APOPTOTIC_EXECUTION__PHASE | 31 | -0.49 | -1.51 | 0.029 | 0.215 | 1.000 | 4346 | tags=35%, list=20%, signal=44% | |
| 68 | NCI_AURORA A SIGNALING | 60 | -0.41 | -1.51 | 0.019 | 0.214 | 1.000 | 4771 | tags=35%, list=22%, signal=45% | |
| 69 | INOH_RAF ACTIVATION SIGNALING (THROUGH RASGRP) | 10 | -0.64 | -1.51 | 0.061 | 0.213 | 1.000 | 1253 | tags=40%, list=6%, signal=42% | |
| 70 | BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY | 15 | -0.57 | -1.51 | 0.041 | 0.215 | 1.000 | 53 | tags=13%, list=0%, signal=13% | |
| 71 | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 | 23 | -0.52 | -1.50 | 0.030 | 0.214 | 1.000 | 3992 | tags=39%, list=18%, signal=48% | |
| 72 | BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS | 25 | -0.50 | -1.50 | 0.044 | 0.213 | 1.000 | 3174 | tags=44%, list=14%, signal=51% | |
| 73 | BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION | 18 | -0.56 | -1.50 | 0.048 | 0.212 | 1.000 | 317 | tags=17%, list=1%, signal=17% | |
| 74 | NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY | 32 | -0.48 | -1.50 | 0.039 | 0.216 | 1.000 | 4349 | tags=34%, list=20%, signal=43% | |
| 75 | NETPATH_BCR | 121 | -0.37 | -1.49 | 0.005 | 0.223 | 1.000 | 5067 | tags=36%, list=23%, signal=47% | |
| 76 | REACTOME_EGFR_DOWNREGULATION | 11 | -0.61 | -1.49 | 0.069 | 0.226 | 1.000 | 474 | tags=18%, list=2%, signal=19% | |
| 77 | CELLMAP_NOTCH | 48 | -0.44 | -1.48 | 0.029 | 0.240 | 1.000 | 3402 | tags=29%, list=16%, signal=34% | |
| 78 | INOH_T CELL RECEPTOR SIGNALING PATHWAY | 52 | -0.42 | -1.48 | 0.020 | 0.237 | 1.000 | 1253 | tags=17%, list=6%, signal=18% | |
| 79 | BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK) | 19 | -0.54 | -1.47 | 0.056 | 0.240 | 1.000 | 4917 | tags=53%, list=22%, signal=68% | |
| 80 | NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1 | 18 | -0.54 | -1.47 | 0.082 | 0.246 | 1.000 | 5318 | tags=61%, list=24%, signal=81% | |
| 81 | NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY | 22 | -0.51 | -1.46 | 0.089 | 0.245 | 1.000 | 159 | tags=9%, list=1%, signal=9% | |
| 82 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 24 | -0.49 | -1.45 | 0.065 | 0.259 | 1.000 | 2422 | tags=33%, list=11%, signal=37% | |
| 83 | BIOCARTA_TPO SIGNALING PATHWAY | 23 | -0.51 | -1.45 | 0.059 | 0.257 | 1.000 | 3931 | tags=39%, list=18%, signal=48% | |
| 84 | NETPATH_IL6 | 60 | -0.41 | -1.45 | 0.027 | 0.258 | 1.000 | 5316 | tags=45%, list=24%, signal=59% | |
| 85 | BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY | 30 | -0.48 | -1.45 | 0.055 | 0.256 | 1.000 | 4974 | tags=47%, list=23%, signal=60% | |
| 86 | NETPATH_FLK2_FLT3 | 16 | -0.55 | -1.44 | 0.076 | 0.266 | 1.000 | 2185 | tags=31%, list=10%, signal=35% | |
| 87 | INOH_NOTCH SECRETORY PATHWAY | 25 | -0.48 | -1.44 | 0.076 | 0.270 | 1.000 | 3410 | tags=32%, list=16%, signal=38% | |
| 88 | NCI_CLASS I PI3K SIGNALING EVENTS | 217 | -0.33 | -1.43 | 0.007 | 0.274 | 1.000 | 4830 | tags=33%, list=22%, signal=42% | |
| 89 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | 25 | -0.48 | -1.43 | 0.069 | 0.272 | 1.000 | 4346 | tags=36%, list=20%, signal=45% | |
| 90 | BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC | 22 | -0.50 | -1.43 | 0.060 | 0.278 | 1.000 | 1288 | tags=27%, list=6%, signal=29% | |
| 91 | BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS | 16 | -0.55 | -1.43 | 0.077 | 0.280 | 1.000 | 2664 | tags=38%, list=12%, signal=43% | |
| 92 | NCI_IL12-MEDIATED SIGNALING EVENTS | 101 | -0.37 | -1.42 | 0.033 | 0.287 | 1.000 | 3731 | tags=32%, list=17%, signal=38% | |
| 93 | BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION | 16 | -0.54 | -1.42 | 0.094 | 0.287 | 1.000 | 2639 | tags=44%, list=12%, signal=50% | |
| 94 | NCI_FOXO FAMILY SIGNALING | 43 | -0.43 | -1.42 | 0.052 | 0.286 | 1.000 | 5351 | tags=47%, list=24%, signal=61% | |
| 95 | INOH_CANONICAL NOTCH SIGNALING PATHWAY | 25 | -0.48 | -1.42 | 0.071 | 0.284 | 1.000 | 3410 | tags=32%, list=16%, signal=38% | |
| 96 | BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION | 44 | -0.43 | -1.41 | 0.043 | 0.286 | 1.000 | 3690 | tags=30%, list=17%, signal=35% | |
| 97 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II | 31 | -0.45 | -1.41 | 0.081 | 0.289 | 1.000 | 1891 | tags=23%, list=9%, signal=25% | |
| 98 | NCI_ENDOTHELINS | 151 | -0.35 | -1.41 | 0.010 | 0.288 | 1.000 | 1939 | tags=15%, list=9%, signal=17% | |
| 99 | INOH_P38 CASCADE | 12 | -0.57 | -1.40 | 0.094 | 0.291 | 1.000 | 1288 | tags=25%, list=6%, signal=27% | |
| 100 | BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING | 32 | -0.45 | -1.40 | 0.078 | 0.300 | 1.000 | 3858 | tags=34%, list=18%, signal=42% | |
| 101 | BIOCARTA_IL 3 SIGNALING PATHWAY | 11 | -0.58 | -1.40 | 0.098 | 0.298 | 1.000 | 3173 | tags=36%, list=14%, signal=42% | |
| 102 | REACTOME_SIGNALLING_BY_NGF | 64 | -0.39 | -1.40 | 0.056 | 0.297 | 1.000 | 3955 | tags=31%, list=18%, signal=38% | |
| 103 | NCI_CERAMIDE SIGNALING PATHWAY | 42 | -0.42 | -1.39 | 0.056 | 0.300 | 1.000 | 1288 | tags=24%, list=6%, signal=25% | |
| 104 | NCI_A4B1 AND A4B7 INTEGRIN SIGNALING | 25 | -0.48 | -1.39 | 0.094 | 0.298 | 1.000 | 5543 | tags=52%, list=25%, signal=70% | |
| 105 | INOH_MAMMALIAN NOTCH SIGNALING PATHWAY | 22 | -0.48 | -1.38 | 0.088 | 0.311 | 1.000 | 3055 | tags=32%, list=14%, signal=37% | |
| 106 | NETPATH_IL5 | 32 | -0.44 | -1.38 | 0.084 | 0.314 | 1.000 | 2185 | tags=22%, list=10%, signal=24% | |
| 107 | BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION | 46 | -0.41 | -1.38 | 0.069 | 0.311 | 1.000 | 3173 | tags=26%, list=14%, signal=30% | |
| 108 | INOH_NOTCH SECRETORY PATHWAY (MAMMAL) | 22 | -0.48 | -1.37 | 0.087 | 0.322 | 1.000 | 3055 | tags=32%, list=14%, signal=37% | |
| 109 | NCI_P75(NTR)-MEDIATED SIGNALING | 165 | -0.33 | -1.37 | 0.028 | 0.321 | 1.000 | 5383 | tags=38%, list=25%, signal=49% | |
| 110 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC) | 25 | -0.47 | -1.37 | 0.093 | 0.322 | 1.000 | 6364 | tags=52%, list=29%, signal=73% | |
| 111 | BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY | 13 | -0.54 | -1.37 | 0.130 | 0.319 | 1.000 | 2938 | tags=31%, list=13%, signal=36% | |
| 112 | NCI_IL23-MEDIATED SIGNALING EVENTS | 60 | -0.38 | -1.36 | 0.061 | 0.323 | 1.000 | 3166 | tags=27%, list=14%, signal=31% | |
| 113 | BIOCARTA_PDGF SIGNALING PATHWAY | 25 | -0.46 | -1.36 | 0.070 | 0.322 | 1.000 | 3592 | tags=32%, list=16%, signal=38% | |
| 114 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE) | 33 | -0.42 | -1.36 | 0.088 | 0.321 | 1.000 | 1253 | tags=18%, list=6%, signal=19% | |
| 115 | INOH_B-RAF ACTIVATION SIGNALING | 29 | -0.44 | -1.36 | 0.086 | 0.321 | 1.000 | 6364 | tags=52%, list=29%, signal=73% | |
| 116 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | 19 | -0.49 | -1.35 | 0.107 | 0.327 | 1.000 | 915 | tags=21%, list=4%, signal=22% | |
| 117 | CELLMAP_EGFR1 | 122 | -0.34 | -1.35 | 0.043 | 0.328 | 1.000 | 3908 | tags=31%, list=18%, signal=38% | |
| 118 | REACTOME_SIGNALING_BY_EGFR | 28 | -0.45 | -1.35 | 0.115 | 0.326 | 1.000 | 5074 | tags=43%, list=23%, signal=56% | |
| 119 | BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE | 28 | -0.45 | -1.35 | 0.089 | 0.324 | 1.000 | 3112 | tags=25%, list=14%, signal=29% | |
| 120 | BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY | 32 | -0.43 | -1.35 | 0.107 | 0.331 | 1.000 | 2871 | tags=28%, list=13%, signal=32% | |
| 121 | NCI_IL4-MEDIATED SIGNALING EVENTS | 57 | -0.38 | -1.34 | 0.080 | 0.334 | 1.000 | 3173 | tags=26%, list=14%, signal=31% | |
| 122 | NCI_ANDROGEN-MEDIATED SIGNALING | 105 | -0.34 | -1.34 | 0.044 | 0.332 | 1.000 | 5772 | tags=39%, list=26%, signal=53% | |
| 123 | BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING | 35 | -0.43 | -1.34 | 0.103 | 0.331 | 1.000 | 1047 | tags=14%, list=5%, signal=15% | |
| 124 | REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | 37 | -0.42 | -1.34 | 0.108 | 0.340 | 1.000 | 3897 | tags=35%, list=18%, signal=43% | |
| 125 | BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE | 14 | -0.51 | -1.34 | 0.148 | 0.337 | 1.000 | 53 | tags=14%, list=0%, signal=14% | |
| 126 | NETPATH_CD40 | 29 | -0.43 | -1.33 | 0.143 | 0.338 | 1.000 | 2897 | tags=31%, list=13%, signal=36% | |
| 127 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I | 88 | -0.35 | -1.33 | 0.054 | 0.336 | 1.000 | 1891 | tags=18%, list=9%, signal=20% | |
| 128 | NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA | 47 | -0.40 | -1.33 | 0.097 | 0.336 | 1.000 | 3751 | tags=28%, list=17%, signal=33% | |
| 129 | NCI_REGULATION OF RETINOBLASTOMA PROTEIN | 60 | -0.38 | -1.33 | 0.076 | 0.334 | 1.000 | 2029 | tags=18%, list=9%, signal=20% | |
| 130 | NCI_EPO SIGNALING PATHWAY | 31 | -0.42 | -1.33 | 0.096 | 0.336 | 1.000 | 5351 | tags=45%, list=24%, signal=60% | |
| 131 | NCI_E-CADHERIN SIGNALING IN THE NASCENT ADHERENS JUNCTION | 43 | -0.39 | -1.33 | 0.087 | 0.337 | 1.000 | 4349 | tags=33%, list=20%, signal=41% | |
| 132 | NCI_IL12 SIGNALING MEDIATED BY STAT4 | 27 | -0.45 | -1.32 | 0.119 | 0.338 | 1.000 | 3592 | tags=41%, list=16%, signal=49% | |
| 133 | BIOCARTA_INTEGRIN SIGNALING PATHWAY | 33 | -0.42 | -1.31 | 0.125 | 0.355 | 1.000 | 4159 | tags=36%, list=19%, signal=45% | |
| 134 | REACTOME_SYNAPTIC_TRANSMISSION | 44 | -0.40 | -1.31 | 0.110 | 0.355 | 1.000 | 2424 | tags=20%, list=11%, signal=23% | |
| 135 | BIOCARTA_BONE REMODELING | 15 | -0.50 | -1.31 | 0.150 | 0.353 | 1.000 | 1047 | tags=13%, list=5%, signal=14% | |
| 136 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 19 | -0.47 | -1.31 | 0.154 | 0.351 | 1.000 | 2185 | tags=26%, list=10%, signal=29% | |
| 137 | REACTOME_DEATH_RECEPTOR__SIGNALLING | 12 | -0.53 | -1.31 | 0.147 | 0.352 | 1.000 | 3415 | tags=42%, list=16%, signal=49% | |
| 138 | INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 17 | -0.50 | -1.31 | 0.143 | 0.353 | 1.000 | 3112 | tags=47%, list=14%, signal=55% | |
| 139 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 44 | -0.40 | -1.31 | 0.107 | 0.351 | 1.000 | 2424 | tags=20%, list=11%, signal=23% | |
| 140 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 19 | -0.47 | -1.31 | 0.131 | 0.350 | 1.000 | 2185 | tags=26%, list=10%, signal=29% | |
| 141 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | 12 | -0.53 | -1.30 | 0.166 | 0.356 | 1.000 | 3415 | tags=42%, list=16%, signal=49% | |
| 142 | BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF) | 16 | -0.49 | -1.30 | 0.150 | 0.354 | 1.000 | 6459 | tags=63%, list=29%, signal=89% | |
| 143 | NCI_LPA RECEPTOR MEDIATED EVENTS | 92 | -0.33 | -1.30 | 0.085 | 0.358 | 1.000 | 4840 | tags=30%, list=22%, signal=39% | |
| 144 | CELLMAP_WNT | 66 | -0.36 | -1.30 | 0.107 | 0.356 | 1.000 | 4565 | tags=36%, list=21%, signal=46% | |
| 145 | NCI_BCR SIGNALING PATHWAY | 63 | -0.37 | -1.29 | 0.093 | 0.365 | 1.000 | 3644 | tags=25%, list=17%, signal=30% | |
| 146 | INOH_ERK CASCADE | 14 | -0.49 | -1.29 | 0.160 | 0.369 | 1.000 | 1253 | tags=21%, list=6%, signal=23% | |
| 147 | BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART | 42 | -0.39 | -1.29 | 0.125 | 0.367 | 1.000 | 1789 | tags=17%, list=8%, signal=18% | |
| 148 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) | 26 | -0.43 | -1.28 | 0.144 | 0.377 | 1.000 | 5003 | tags=42%, list=23%, signal=55% | |
| 149 | BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY | 17 | -0.48 | -1.28 | 0.162 | 0.379 | 1.000 | 1084 | tags=18%, list=5%, signal=19% | |
| 150 | NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING | 46 | -0.38 | -1.28 | 0.125 | 0.382 | 1.000 | 1084 | tags=15%, list=5%, signal=16% | |
| 151 | BIOCARTA_NF-KB SIGNALING PATHWAY | 21 | -0.46 | -1.27 | 0.163 | 0.382 | 1.000 | 1288 | tags=19%, list=6%, signal=20% | |
| 152 | BIOCARTA_SEGMENTATION CLOCK | 20 | -0.46 | -1.27 | 0.168 | 0.388 | 1.000 | 1573 | tags=25%, list=7%, signal=27% | |
| 153 | NCI_SIGNALING BY AURORA KINASES | 88 | -0.33 | -1.27 | 0.098 | 0.386 | 1.000 | 2528 | tags=20%, list=12%, signal=23% | |
| 154 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 17 | -0.46 | -1.27 | 0.187 | 0.386 | 1.000 | 3955 | tags=35%, list=18%, signal=43% | |
| 155 | REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS | 14 | -0.51 | -1.27 | 0.185 | 0.384 | 1.000 | 4617 | tags=50%, list=21%, signal=63% | |
| 156 | BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1 | 13 | -0.50 | -1.27 | 0.204 | 0.386 | 1.000 | 3841 | tags=46%, list=18%, signal=56% | |
| 157 | BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY | 11 | -0.54 | -1.27 | 0.208 | 0.385 | 1.000 | 4060 | tags=55%, list=19%, signal=67% | |
| 158 | NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY | 84 | -0.34 | -1.27 | 0.093 | 0.382 | 1.000 | 5010 | tags=33%, list=23%, signal=43% | |
| 159 | REACTOME_OPIOID_SIGNALLING | 23 | -0.43 | -1.27 | 0.181 | 0.380 | 1.000 | 4465 | tags=39%, list=20%, signal=49% | |
| 160 | BIOCARTA_REGULATION OF P27 PHOSPHORYLATION DURING CELL CYCLE PROGRESSION | 11 | -0.52 | -1.26 | 0.188 | 0.392 | 1.000 | 5454 | tags=55%, list=25%, signal=73% | |
| 161 | BIOCARTA_EPO SIGNALING PATHWAY | 10 | -0.53 | -1.25 | 0.195 | 0.399 | 1.000 | 1084 | tags=20%, list=5%, signal=21% | |
| 162 | REACTOME_CELL_JUNCTION_ORGANIZATION | 25 | -0.42 | -1.25 | 0.173 | 0.399 | 1.000 | 3856 | tags=44%, list=18%, signal=53% | |
| 163 | BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD | 15 | -0.48 | -1.25 | 0.210 | 0.403 | 1.000 | 3690 | tags=40%, list=17%, signal=48% | |
| 164 | BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME | 10 | -0.53 | -1.25 | 0.204 | 0.401 | 1.000 | 3841 | tags=40%, list=18%, signal=48% | |
| 165 | NETPATH_IFN-GAMMA | 71 | -0.34 | -1.24 | 0.127 | 0.404 | 1.000 | 3731 | tags=34%, list=17%, signal=41% | |
| 166 | BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY | 16 | -0.46 | -1.23 | 0.200 | 0.423 | 1.000 | 2346 | tags=25%, list=11%, signal=28% | |
| 167 | BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY | 28 | -0.41 | -1.23 | 0.191 | 0.425 | 1.000 | 3841 | tags=36%, list=18%, signal=43% | |
| 168 | INOH_PHOSPHOLIPASE C GAMMA SIGNALING | 49 | -0.35 | -1.23 | 0.159 | 0.428 | 1.000 | 1253 | tags=14%, list=6%, signal=15% | |
| 169 | BIOCARTA_IL-7 SIGNAL TRANSDUCTION | 15 | -0.46 | -1.22 | 0.229 | 0.435 | 1.000 | 1678 | tags=27%, list=8%, signal=29% | |
| 170 | NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7 | 22 | -0.42 | -1.22 | 0.207 | 0.440 | 1.000 | 5543 | tags=50%, list=25%, signal=67% | |
| 171 | INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR) | 15 | -0.46 | -1.22 | 0.222 | 0.439 | 1.000 | 1253 | tags=20%, list=6%, signal=21% | |
| 172 | INOH_B CELL RECEPTOR SIGNALING PATHWAY | 71 | -0.33 | -1.22 | 0.146 | 0.444 | 1.000 | 4738 | tags=34%, list=22%, signal=43% | |
| 173 | INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE | 36 | -0.38 | -1.21 | 0.206 | 0.443 | 1.000 | 5351 | tags=42%, list=24%, signal=55% | |
| 174 | BIOCARTA_REGULATION OF CELL CYCLE PROGRESSION BY PLK3 | 17 | -0.45 | -1.21 | 0.220 | 0.443 | 1.000 | 53 | tags=12%, list=0%, signal=12% | |
| 175 | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY | 132 | -0.30 | -1.21 | 0.127 | 0.453 | 1.000 | 4889 | tags=32%, list=22%, signal=41% | |
| 176 | NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY | 120 | -0.30 | -1.21 | 0.122 | 0.451 | 1.000 | 3592 | tags=24%, list=16%, signal=29% | |
| 177 | BIOCARTA_IGF-1 SIGNALING PATHWAY | 20 | -0.43 | -1.21 | 0.221 | 0.450 | 1.000 | 6459 | tags=50%, list=29%, signal=71% | |
| 178 | NCI_IL6-MEDIATED SIGNALING EVENTS | 43 | -0.36 | -1.20 | 0.213 | 0.458 | 1.000 | 3592 | tags=28%, list=16%, signal=33% | |
| 179 | CELLMAP_KITRECEPTOR | 49 | -0.35 | -1.20 | 0.203 | 0.456 | 1.000 | 4461 | tags=35%, list=20%, signal=43% | |
| 180 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II | 27 | -0.40 | -1.20 | 0.205 | 0.455 | 1.000 | 4021 | tags=33%, list=18%, signal=41% | |
| 181 | BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES | 24 | -0.41 | -1.20 | 0.216 | 0.457 | 1.000 | 3841 | tags=33%, list=18%, signal=40% | |
| 182 | INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS) | 12 | -0.48 | -1.19 | 0.250 | 0.465 | 1.000 | 1253 | tags=25%, list=6%, signal=27% | |
| 183 | BIOCARTA_FAS SIGNALING PATHWAY (CD95) | 19 | -0.43 | -1.19 | 0.244 | 0.466 | 1.000 | 3415 | tags=37%, list=16%, signal=44% | |
| 184 | NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION | 19 | -0.44 | -1.19 | 0.251 | 0.465 | 1.000 | 3252 | tags=26%, list=15%, signal=31% | |
| 185 | INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 10 | -0.51 | -1.19 | 0.251 | 0.462 | 1.000 | 2184 | tags=30%, list=10%, signal=33% | |
| 186 | NCI_NONGENOTROPIC ANDROGEN SIGNALING | 24 | -0.40 | -1.18 | 0.236 | 0.474 | 1.000 | 3551 | tags=29%, list=16%, signal=35% | |
| 187 | NCI_IGF1 PATHWAY | 132 | -0.29 | -1.18 | 0.155 | 0.477 | 1.000 | 4487 | tags=27%, list=20%, signal=34% | |
| 188 | NCI_GLYPICAN 3 NETWORK | 57 | -0.33 | -1.18 | 0.197 | 0.478 | 1.000 | 4889 | tags=33%, list=22%, signal=43% | |
| 189 | CELLMAP_ANDROGENRECEPTOR | 74 | -0.32 | -1.18 | 0.199 | 0.482 | 1.000 | 4958 | tags=42%, list=23%, signal=54% | |
| 190 | NCI_FGF SIGNALING PATHWAY | 46 | -0.35 | -1.18 | 0.221 | 0.479 | 1.000 | 3592 | tags=24%, list=16%, signal=29% | |
| 191 | INOH_SIGNALING WITHOUT WNT (MAMMAL) | 25 | -0.40 | -1.18 | 0.244 | 0.478 | 1.000 | 5626 | tags=48%, list=26%, signal=64% | |
| 192 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | 16 | -0.45 | -1.18 | 0.265 | 0.476 | 1.000 | 3109 | tags=38%, list=14%, signal=44% | |
| 193 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 54 | -0.34 | -1.17 | 0.217 | 0.477 | 1.000 | 5052 | tags=26%, list=23%, signal=34% | |
| 194 | CELLMAP_TNF ALPHA/NF-KB | 156 | -0.28 | -1.17 | 0.127 | 0.481 | 1.000 | 3551 | tags=26%, list=16%, signal=30% | |
| 195 | BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION | 17 | -0.44 | -1.17 | 0.268 | 0.488 | 1.000 | 4243 | tags=41%, list=19%, signal=51% | |
| 196 | REACTOME_LOSS_OF_PROTEINS_REQUIRED_FOR_INTERPHASE_MICROTUBULE_ORGANIZATION_FROM_THE_CENTROSOME | 38 | -0.36 | -1.16 | 0.234 | 0.495 | 1.000 | 3780 | tags=29%, list=17%, signal=35% | |
| 197 | NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING | 41 | -0.35 | -1.16 | 0.235 | 0.494 | 1.000 | 3592 | tags=32%, list=16%, signal=38% | |
| 198 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY | 33 | -0.37 | -1.16 | 0.273 | 0.496 | 1.000 | 2534 | tags=21%, list=12%, signal=24% | |
| 199 | INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING | 11 | -0.48 | -1.16 | 0.300 | 0.494 | 1.000 | 3674 | tags=45%, list=17%, signal=55% | |
| 200 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I | 14 | -0.46 | -1.16 | 0.288 | 0.493 | 1.000 | 1155 | tags=21%, list=5%, signal=23% | |
| 201 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | 11 | -0.48 | -1.16 | 0.312 | 0.494 | 1.000 | 4786 | tags=45%, list=22%, signal=58% | |
| 202 | NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS | 241 | -0.26 | -1.15 | 0.144 | 0.502 | 1.000 | 4487 | tags=26%, list=20%, signal=33% | |
| 203 | NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE | 67 | -0.32 | -1.15 | 0.220 | 0.502 | 1.000 | 5351 | tags=34%, list=24%, signal=45% | |
| 204 | NCI_CANONICAL NF-KAPPAB PATHWAY | 34 | -0.36 | -1.15 | 0.251 | 0.501 | 1.000 | 4738 | tags=32%, list=22%, signal=41% | |
| 205 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 14 | -0.45 | -1.15 | 0.300 | 0.502 | 1.000 | 242 | tags=14%, list=1%, signal=14% | |
| 206 | NCI_S1P4 PATHWAY | 12 | -0.46 | -1.14 | 0.298 | 0.508 | 1.000 | 2185 | tags=33%, list=10%, signal=37% | |
| 207 | NCI_INSULIN PATHWAY | 120 | -0.28 | -1.14 | 0.200 | 0.508 | 1.000 | 4487 | tags=27%, list=20%, signal=33% | |
| 208 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA | 57 | -0.33 | -1.14 | 0.256 | 0.508 | 1.000 | 4974 | tags=35%, list=23%, signal=45% | |
| 209 | REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL | 23 | -0.39 | -1.14 | 0.288 | 0.511 | 1.000 | 2185 | tags=22%, list=10%, signal=24% | |
| 210 | NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS | 157 | -0.28 | -1.14 | 0.193 | 0.511 | 1.000 | 4487 | tags=27%, list=20%, signal=34% | |
| 211 | INOH_PKA ACTIVATION SIGNALING | 49 | -0.34 | -1.13 | 0.229 | 0.517 | 1.000 | 3674 | tags=24%, list=17%, signal=29% | |
| 212 | REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_ | 90 | -0.29 | -1.13 | 0.216 | 0.515 | 1.000 | 3346 | tags=14%, list=15%, signal=17% | |
| 213 | NETPATH_IFN-ALPHA | 44 | -0.34 | -1.13 | 0.278 | 0.527 | 1.000 | 3173 | tags=30%, list=14%, signal=34% | |
| 214 | NCI_ARF6 SIGNALING EVENTS | 120 | -0.28 | -1.12 | 0.227 | 0.528 | 1.000 | 4487 | tags=27%, list=20%, signal=33% | |
| 215 | BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION | 13 | -0.44 | -1.12 | 0.326 | 0.527 | 1.000 | 952 | tags=15%, list=4%, signal=16% | |
| 216 | NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY | 44 | -0.33 | -1.12 | 0.272 | 0.542 | 1.000 | 4714 | tags=32%, list=21%, signal=40% | |
| 217 | REACTOME_CENTROSOME_MATURATION | 40 | -0.34 | -1.11 | 0.310 | 0.550 | 1.000 | 3780 | tags=28%, list=17%, signal=33% | |
| 218 | NCI_ARF6 TRAFFICKING EVENTS | 120 | -0.28 | -1.11 | 0.238 | 0.548 | 1.000 | 4487 | tags=27%, list=20%, signal=33% | |
| 219 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | 40 | -0.34 | -1.11 | 0.287 | 0.554 | 1.000 | 3780 | tags=28%, list=17%, signal=33% | |
| 220 | NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING | 93 | -0.29 | -1.10 | 0.278 | 0.571 | 1.000 | 2534 | tags=19%, list=12%, signal=22% | |
| 221 | NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING | 38 | -0.33 | -1.10 | 0.313 | 0.569 | 1.000 | 3280 | tags=26%, list=15%, signal=31% | |
| 222 | BIOCARTA_REGULATION OF PGC-1A | 18 | -0.40 | -1.09 | 0.359 | 0.578 | 1.000 | 1874 | tags=28%, list=9%, signal=30% | |
| 223 | NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK | 35 | -0.34 | -1.09 | 0.330 | 0.583 | 1.000 | 5751 | tags=49%, list=26%, signal=66% | |
| 224 | REACTOME_PHASE_1_FUNCTIONALIZATION | 10 | -0.46 | -1.09 | 0.357 | 0.581 | 1.000 | 1740 | tags=20%, list=8%, signal=22% | |
| 225 | BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT | 15 | -0.41 | -1.08 | 0.368 | 0.590 | 1.000 | 1739 | tags=20%, list=8%, signal=22% | |
| 226 | REACTOME_TCR_SIGNALING | 33 | -0.35 | -1.08 | 0.339 | 0.593 | 1.000 | 4753 | tags=39%, list=22%, signal=50% | |
| 227 | NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET) | 149 | -0.27 | -1.08 | 0.286 | 0.597 | 1.000 | 4487 | tags=28%, list=20%, signal=34% | |
| 228 | BIOCARTA_IL 2 SIGNALING PATHWAY | 13 | -0.43 | -1.08 | 0.388 | 0.598 | 1.000 | 1678 | tags=23%, list=8%, signal=25% | |
| 229 | INOH_PLC BETA SIGNALING | 19 | -0.39 | -1.07 | 0.381 | 0.601 | 1.000 | 1253 | tags=16%, list=6%, signal=17% | |
| 230 | REACTOME_PLATELET_ACTIVATION_TRIGGERS | 24 | -0.37 | -1.07 | 0.361 | 0.602 | 1.000 | 4738 | tags=42%, list=22%, signal=53% | |
| 231 | REACTOME_DOWNSTREAM_TCR_SIGNALING | 20 | -0.38 | -1.07 | 0.365 | 0.611 | 1.000 | 4738 | tags=45%, list=22%, signal=57% | |
| 232 | INOH_JNK CASCADE | 16 | -0.40 | -1.07 | 0.373 | 0.611 | 1.000 | 1288 | tags=19%, list=6%, signal=20% | |
| 233 | BIOCARTA_ADP-RIBOSYLATION FACTOR | 18 | -0.38 | -1.06 | 0.370 | 0.617 | 1.000 | 4418 | tags=56%, list=20%, signal=70% | |
| 234 | BIOCARTA_PTEN DEPENDENT CELL CYCLE ARREST AND APOPTOSIS | 14 | -0.41 | -1.06 | 0.377 | 0.619 | 1.000 | 6459 | tags=50%, list=29%, signal=71% | |
| 235 | NCI_CANONICAL WNT SIGNALING PATHWAY | 49 | -0.31 | -1.06 | 0.357 | 0.619 | 1.000 | 1774 | tags=14%, list=8%, signal=16% | |
| 236 | INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING) | 30 | -0.34 | -1.06 | 0.385 | 0.616 | 1.000 | 1084 | tags=13%, list=5%, signal=14% | |
| 237 | NCI_S1P3 PATHWAY | 24 | -0.36 | -1.06 | 0.375 | 0.616 | 1.000 | 3551 | tags=29%, list=16%, signal=35% | |
| 238 | NCI_WNT SIGNALING | 49 | -0.31 | -1.06 | 0.374 | 0.615 | 1.000 | 1774 | tags=14%, list=8%, signal=16% | |
| 239 | INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER | 30 | -0.34 | -1.05 | 0.413 | 0.618 | 1.000 | 1084 | tags=13%, list=5%, signal=14% | |
| 240 | INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING | 193 | -0.25 | -1.05 | 0.316 | 0.616 | 1.000 | 3575 | tags=19%, list=16%, signal=22% | |
| 241 | INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING | 107 | -0.27 | -1.05 | 0.351 | 0.617 | 1.000 | 5345 | tags=26%, list=24%, signal=34% | |
| 242 | BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR | 36 | -0.32 | -1.04 | 0.401 | 0.632 | 1.000 | 3109 | tags=28%, list=14%, signal=32% | |
| 243 | BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS | 23 | -0.36 | -1.04 | 0.409 | 0.634 | 1.000 | 5486 | tags=43%, list=25%, signal=58% | |
| 244 | REACTOME_CD28_CO_STIMULATION | 13 | -0.41 | -1.04 | 0.389 | 0.632 | 1.000 | 887 | tags=15%, list=4%, signal=16% | |
| 245 | NCI_REELIN SIGNALING PATHWAY | 27 | -0.35 | -1.04 | 0.417 | 0.630 | 1.000 | 5351 | tags=37%, list=24%, signal=49% | |
| 246 | BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR | 17 | -0.40 | -1.04 | 0.438 | 0.630 | 1.000 | 1288 | tags=18%, list=6%, signal=19% | |
| 247 | REACTOME_PI3K_AKT_SIGNALLING | 13 | -0.42 | -1.04 | 0.417 | 0.630 | 1.000 | 5772 | tags=54%, list=26%, signal=73% | |
| 248 | NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT | 24 | -0.36 | -1.04 | 0.406 | 0.630 | 1.000 | 4797 | tags=38%, list=22%, signal=48% | |
| 249 | BIOCARTA_RAS SIGNALING PATHWAY | 19 | -0.38 | -1.03 | 0.413 | 0.636 | 1.000 | 5282 | tags=37%, list=24%, signal=48% | |
| 250 | REACTOME_SHC_RELATED_EVENTS | 10 | -0.45 | -1.03 | 0.444 | 0.637 | 1.000 | 2185 | tags=30%, list=10%, signal=33% | |
| 251 | NCI_INTEGRINS IN ANGIOGENESIS | 62 | -0.29 | -1.03 | 0.421 | 0.637 | 1.000 | 5751 | tags=40%, list=26%, signal=54% | |
| 252 | NETPATH_GDNF | 29 | -0.34 | -1.03 | 0.425 | 0.640 | 1.000 | 5046 | tags=41%, list=23%, signal=54% | |
| 253 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | 10 | -0.45 | -1.03 | 0.445 | 0.644 | 1.000 | 2321 | tags=40%, list=11%, signal=45% | |
| 254 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G) | 13 | -0.40 | -1.03 | 0.423 | 0.642 | 1.000 | 952 | tags=15%, list=4%, signal=16% | |
| 255 | REACTOME_TOLL_LIKE_RECEPTOR_4__TLR4__CASCADE | 10 | -0.44 | -1.02 | 0.418 | 0.646 | 1.000 | 1296 | tags=20%, list=6%, signal=21% | |
| 256 | BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES | 15 | -0.39 | -1.02 | 0.429 | 0.648 | 1.000 | 2185 | tags=27%, list=10%, signal=30% | |
| 257 | REACTOME_SIGNALLING_TO_RAS | 12 | -0.42 | -1.02 | 0.442 | 0.659 | 1.000 | 2185 | tags=25%, list=10%, signal=28% | |
| 258 | BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION | 21 | -0.35 | -1.01 | 0.427 | 0.666 | 1.000 | 3841 | tags=38%, list=18%, signal=46% | |
| 259 | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | 59 | -0.28 | -1.01 | 0.441 | 0.669 | 1.000 | 1237 | tags=10%, list=6%, signal=11% | |
| 260 | BIOCARTA_GRANZYME A MEDIATED APOPTOSIS PATHWAY | 11 | -0.42 | -1.01 | 0.432 | 0.668 | 1.000 | 2511 | tags=36%, list=11%, signal=41% | |
| 261 | BIOCARTA_CYCLINS AND CELL CYCLE REGULATION | 21 | -0.36 | -1.01 | 0.448 | 0.667 | 1.000 | 78 | tags=10%, list=0%, signal=10% | |
| 262 | CELLMAP_TGFBR | 105 | -0.25 | -1.01 | 0.438 | 0.664 | 1.000 | 4976 | tags=37%, list=23%, signal=48% | |
| 263 | REACTOME_SPHINGOLIPID_METABOLISM | 10 | -0.44 | -1.01 | 0.476 | 0.664 | 1.000 | 2156 | tags=30%, list=10%, signal=33% | |
| 264 | BIOCARTA_EFFECTS OF CALCINEURIN IN KERATINOCYTE DIFFERENTIATION | 12 | -0.40 | -1.00 | 0.467 | 0.668 | 1.000 | 2664 | tags=25%, list=12%, signal=28% | |
| 265 | CELLMAP_ID | 13 | -0.40 | -1.00 | 0.461 | 0.669 | 1.000 | 3416 | tags=23%, list=16%, signal=27% | |
| 266 | INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL) | 20 | -0.36 | -1.00 | 0.438 | 0.669 | 1.000 | 5626 | tags=45%, list=26%, signal=60% | |
| 267 | REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING | 10 | -0.43 | -1.00 | 0.482 | 0.672 | 1.000 | 2185 | tags=30%, list=10%, signal=33% | |
| 268 | BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY | 17 | -0.37 | -1.00 | 0.458 | 0.669 | 1.000 | 1047 | tags=12%, list=5%, signal=12% | |
| 269 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE) | 20 | -0.35 | -1.00 | 0.467 | 0.671 | 1.000 | 1288 | tags=15%, list=6%, signal=16% | |
| 270 | REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | 21 | -0.36 | -1.00 | 0.504 | 0.669 | 1.000 | 4738 | tags=38%, list=22%, signal=49% | |
| 271 | INOH_SIGNALING WITHOUT WNT (CANONICAL) | 29 | -0.33 | -0.99 | 0.489 | 0.681 | 1.000 | 5626 | tags=41%, list=26%, signal=56% | |
| 272 | BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY | 19 | -0.36 | -0.99 | 0.473 | 0.679 | 1.000 | 3173 | tags=26%, list=14%, signal=31% | |
| 273 | REACTOME_SIGNALLING_TO_ERKS | 14 | -0.38 | -0.99 | 0.492 | 0.679 | 1.000 | 2185 | tags=21%, list=10%, signal=24% | |
| 274 | NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5 | 27 | -0.33 | -0.98 | 0.468 | 0.683 | 1.000 | 3824 | tags=26%, list=17%, signal=31% | |
| 275 | INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING) | 18 | -0.36 | -0.98 | 0.472 | 0.682 | 1.000 | 5816 | tags=39%, list=27%, signal=53% | |
| 276 | HUMANCYC_CDP-DIACYLGLYCEROL BIOSYNTHESIS I | 10 | -0.42 | -0.98 | 0.491 | 0.681 | 1.000 | 1155 | tags=20%, list=5%, signal=21% | |
| 277 | NCI_ALPHA-SYNUCLEIN SIGNALING | 31 | -0.31 | -0.98 | 0.476 | 0.683 | 1.000 | 5510 | tags=45%, list=25%, signal=60% | |
| 278 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | 24 | -0.33 | -0.98 | 0.512 | 0.684 | 1.000 | 3284 | tags=29%, list=15%, signal=34% | |
| 279 | NETPATH_TIE1_TEK | 25 | -0.34 | -0.98 | 0.480 | 0.684 | 1.000 | 1084 | tags=12%, list=5%, signal=13% | |
| 280 | BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES | 28 | -0.33 | -0.98 | 0.475 | 0.682 | 1.000 | 2185 | tags=21%, list=10%, signal=24% | |
| 281 | REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING | 11 | -0.41 | -0.98 | 0.500 | 0.680 | 1.000 | 2185 | tags=27%, list=10%, signal=30% | |
| 282 | NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT | 84 | -0.26 | -0.98 | 0.508 | 0.681 | 1.000 | 4830 | tags=31%, list=22%, signal=40% | |
| 283 | HUMANCYC_CDP-DIACYLGLYCEROL BIOSYNTHESIS II | 10 | -0.42 | -0.97 | 0.499 | 0.686 | 1.000 | 1155 | tags=20%, list=5%, signal=21% | |
| 284 | REACTOME_SIGNALING_BY_GPCR | 139 | -0.24 | -0.96 | 0.544 | 0.702 | 1.000 | 3346 | tags=14%, list=15%, signal=16% | |
| 285 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | 12 | -0.39 | -0.96 | 0.531 | 0.713 | 1.000 | 3199 | tags=42%, list=15%, signal=49% | |
| 286 | NCI_S1P2 PATHWAY | 23 | -0.33 | -0.96 | 0.530 | 0.713 | 1.000 | 3592 | tags=26%, list=16%, signal=31% | |
| 287 | INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY | 194 | -0.22 | -0.95 | 0.596 | 0.725 | 1.000 | 3575 | tags=19%, list=16%, signal=22% | |
| 288 | INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING) | 17 | -0.35 | -0.95 | 0.539 | 0.734 | 1.000 | 135 | tags=6%, list=1%, signal=6% | |
| 289 | BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS | 20 | -0.33 | -0.94 | 0.552 | 0.736 | 1.000 | 2185 | tags=20%, list=10%, signal=22% | |
| 290 | BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY | 35 | -0.29 | -0.94 | 0.529 | 0.737 | 1.000 | 3592 | tags=26%, list=16%, signal=31% | |
| 291 | BIOCARTA_CELL CYCLE: G2/M CHECKPOINT | 20 | -0.34 | -0.94 | 0.536 | 0.742 | 1.000 | 4369 | tags=35%, list=20%, signal=44% | |
| 292 | NCI_NECTIN ADHESION PATHWAY | 99 | -0.25 | -0.94 | 0.601 | 0.745 | 1.000 | 4349 | tags=26%, list=20%, signal=33% | |
| 293 | NCI_THROMBOXANE A2 RECEPTOR SIGNALING | 50 | -0.28 | -0.93 | 0.573 | 0.753 | 1.000 | 4840 | tags=30%, list=22%, signal=38% | |
| 294 | BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE | 20 | -0.34 | -0.93 | 0.576 | 0.751 | 1.000 | 3894 | tags=30%, list=18%, signal=36% | |
| 295 | REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION | 19 | -0.34 | -0.93 | 0.584 | 0.749 | 1.000 | 2029 | tags=26%, list=9%, signal=29% | |
| 296 | INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 17 | -0.35 | -0.93 | 0.566 | 0.754 | 1.000 | 135 | tags=6%, list=1%, signal=6% | |
| 297 | BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB | 12 | -0.38 | -0.93 | 0.552 | 0.752 | 1.000 | 3718 | tags=33%, list=17%, signal=40% | |
| 298 | BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY | 24 | -0.32 | -0.93 | 0.573 | 0.749 | 1.000 | 2185 | tags=21%, list=10%, signal=23% | |
| 299 | INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 18 | -0.34 | -0.93 | 0.589 | 0.750 | 1.000 | 135 | tags=6%, list=1%, signal=6% | |
| 300 | NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS | 72 | -0.25 | -0.92 | 0.608 | 0.750 | 1.000 | 3716 | tags=19%, list=17%, signal=23% | |
| 301 | BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA | 36 | -0.29 | -0.92 | 0.582 | 0.749 | 1.000 | 2938 | tags=22%, list=13%, signal=26% | |
| 302 | REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES | 64 | -0.26 | -0.92 | 0.590 | 0.750 | 1.000 | 1508 | tags=11%, list=7%, signal=12% | |
| 303 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | 18 | -0.34 | -0.91 | 0.595 | 0.766 | 1.000 | 2185 | tags=22%, list=10%, signal=25% | |
| 304 | BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY | 14 | -0.36 | -0.91 | 0.581 | 0.764 | 1.000 | 3551 | tags=29%, list=16%, signal=34% | |
| 305 | HUMANCYC_SALVAGE PATHWAYS OF PYRIMIDINE RIBONUCLEOTIDES | 13 | -0.36 | -0.91 | 0.584 | 0.776 | 1.000 | 1352 | tags=23%, list=6%, signal=25% | |
| 306 | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING | 32 | -0.29 | -0.90 | 0.621 | 0.781 | 1.000 | 1264 | tags=16%, list=6%, signal=17% | |
| 307 | REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE | 15 | -0.34 | -0.90 | 0.601 | 0.786 | 1.000 | 3592 | tags=27%, list=16%, signal=32% | |
| 308 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE) | 19 | -0.32 | -0.90 | 0.606 | 0.790 | 1.000 | 1288 | tags=16%, list=6%, signal=17% | |
| 309 | BIOCARTA_EGF SIGNALING PATHWAY | 19 | -0.32 | -0.89 | 0.617 | 0.791 | 1.000 | 6459 | tags=47%, list=29%, signal=67% | |
| 310 | BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS | 22 | -0.31 | -0.89 | 0.594 | 0.798 | 1.000 | 2185 | tags=14%, list=10%, signal=15% | |
| 311 | REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S | 13 | -0.35 | -0.89 | 0.604 | 0.803 | 1.000 | 3114 | tags=31%, list=14%, signal=36% | |
| 312 | NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA | 66 | -0.24 | -0.89 | 0.673 | 0.801 | 1.000 | 3112 | tags=23%, list=14%, signal=26% | |
| 313 | REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 15 | -0.34 | -0.88 | 0.624 | 0.803 | 1.000 | 2185 | tags=20%, list=10%, signal=22% | |
| 314 | BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM | 14 | -0.34 | -0.88 | 0.606 | 0.800 | 1.000 | 5751 | tags=50%, list=26%, signal=68% | |
| 315 | BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS | 15 | -0.34 | -0.88 | 0.619 | 0.804 | 1.000 | 4738 | tags=33%, list=22%, signal=42% | |
| 316 | NCI_A6B1 AND A6B4 INTEGRIN SIGNALING | 43 | -0.26 | -0.88 | 0.663 | 0.804 | 1.000 | 1866 | tags=9%, list=9%, signal=10% | |
| 317 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE | 13 | -0.35 | -0.88 | 0.645 | 0.807 | 1.000 | 3592 | tags=31%, list=16%, signal=37% | |
| 318 | NCI_IL27-MEDIATED SIGNALING EVENTS | 24 | -0.30 | -0.87 | 0.641 | 0.811 | 1.000 | 3318 | tags=29%, list=15%, signal=34% | |
| 319 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | 23 | -0.30 | -0.87 | 0.636 | 0.814 | 1.000 | 2295 | tags=17%, list=10%, signal=19% | |
| 320 | BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY | 21 | -0.31 | -0.87 | 0.659 | 0.813 | 1.000 | 3551 | tags=29%, list=16%, signal=34% | |
| 321 | BIOCARTA_B CELL SURVIVAL PATHWAY | 13 | -0.34 | -0.86 | 0.621 | 0.826 | 1.000 | 2512 | tags=23%, list=11%, signal=26% | |
| 322 | NCI_SIGNALING EVENTS MEDIATED BY PRL | 22 | -0.30 | -0.86 | 0.634 | 0.824 | 1.000 | 3858 | tags=32%, list=18%, signal=39% | |
| 323 | BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION | 27 | -0.29 | -0.86 | 0.674 | 0.823 | 1.000 | 2185 | tags=19%, list=10%, signal=21% | |
| 324 | REACTOME_G2_M_TRANSITION | 51 | -0.25 | -0.86 | 0.696 | 0.823 | 1.000 | 3780 | tags=27%, list=17%, signal=33% | |
| 325 | REACTOME_SIGNALING_BY_PDGF | 21 | -0.30 | -0.86 | 0.663 | 0.821 | 1.000 | 3926 | tags=33%, list=18%, signal=41% | |
| 326 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL) | 29 | -0.28 | -0.86 | 0.668 | 0.821 | 1.000 | 5626 | tags=34%, list=26%, signal=46% | |
| 327 | REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | 16 | -0.32 | -0.85 | 0.656 | 0.832 | 1.000 | 6610 | tags=44%, list=30%, signal=63% | |
| 328 | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS | 47 | -0.25 | -0.85 | 0.736 | 0.832 | 1.000 | 4937 | tags=32%, list=23%, signal=41% | |
| 329 | NCI_CIRCADIAN RHYTHM PATHWAY | 11 | -0.35 | -0.85 | 0.631 | 0.832 | 1.000 | 3565 | tags=27%, list=16%, signal=33% | |
| 330 | BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R | 35 | -0.27 | -0.84 | 0.714 | 0.839 | 1.000 | 1288 | tags=11%, list=6%, signal=12% | |
| 331 | REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS | 23 | -0.30 | -0.84 | 0.703 | 0.838 | 1.000 | 2295 | tags=17%, list=10%, signal=19% | |
| 332 | NCI_FOXA TRANSCRIPTION FACTOR NETWORKS | 66 | -0.23 | -0.83 | 0.771 | 0.849 | 1.000 | 5907 | tags=39%, list=27%, signal=54% | |
| 333 | INOH_SIGNALING WITH WNT (MAMMAL) | 53 | -0.24 | -0.83 | 0.773 | 0.864 | 1.000 | 5867 | tags=36%, list=27%, signal=49% | |
| 334 | REACTOME_TOLL_RECEPTOR_CASCADES | 27 | -0.27 | -0.83 | 0.730 | 0.861 | 1.000 | 5562 | tags=33%, list=25%, signal=45% | |
| 335 | INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL) | 24 | -0.28 | -0.82 | 0.741 | 0.864 | 1.000 | 5626 | tags=38%, list=26%, signal=50% | |
| 336 | NCI_SIGNALING EVENTS MEDIATED BY PTP1B | 45 | -0.24 | -0.81 | 0.787 | 0.877 | 1.000 | 4779 | tags=29%, list=22%, signal=37% | |
| 337 | NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR | 19 | -0.30 | -0.81 | 0.750 | 0.884 | 1.000 | 726 | tags=11%, list=3%, signal=11% | |
| 338 | NCI_AMB2 INTEGRIN SIGNALING | 47 | -0.24 | -0.81 | 0.798 | 0.883 | 1.000 | 5437 | tags=34%, list=25%, signal=45% | |
| 339 | REACTOME_HEMOSTASIS | 144 | -0.20 | -0.80 | 0.908 | 0.886 | 1.000 | 4738 | tags=22%, list=22%, signal=28% | |
| 340 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 12 | -0.33 | -0.80 | 0.727 | 0.886 | 1.000 | 4738 | tags=58%, list=22%, signal=74% | |
| 341 | BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES | 37 | -0.25 | -0.80 | 0.783 | 0.890 | 1.000 | 1515 | tags=14%, list=7%, signal=14% | |
| 342 | BIOCARTA_TGF BETA SIGNALING PATHWAY | 20 | -0.29 | -0.79 | 0.760 | 0.893 | 1.000 | 3112 | tags=25%, list=14%, signal=29% | |
| 343 | REACTOME_SIGNALING_IN_IMMUNE_SYSTEM | 138 | -0.20 | -0.79 | 0.910 | 0.895 | 1.000 | 4753 | tags=26%, list=22%, signal=33% | |
| 344 | REACTOME_METABOLISM_OF_MRNA | 21 | -0.28 | -0.79 | 0.766 | 0.894 | 1.000 | 4314 | tags=33%, list=20%, signal=41% | |
| 345 | INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I) | 12 | -0.32 | -0.79 | 0.745 | 0.899 | 1.000 | 3112 | tags=33%, list=14%, signal=39% | |
| 346 | INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4 | 12 | -0.32 | -0.78 | 0.739 | 0.900 | 1.000 | 3112 | tags=33%, list=14%, signal=39% | |
| 347 | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | 21 | -0.28 | -0.78 | 0.756 | 0.899 | 1.000 | 4314 | tags=33%, list=20%, signal=41% | |
| 348 | BIOCARTA_CONTROL OF GENE EXPRESSION BY VITAMIN D RECEPTOR | 24 | -0.26 | -0.78 | 0.827 | 0.898 | 1.000 | 2938 | tags=25%, list=13%, signal=29% | |
| 349 | BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY | 16 | -0.29 | -0.78 | 0.771 | 0.898 | 1.000 | 3841 | tags=31%, list=18%, signal=38% | |
| 350 | BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT | 15 | -0.30 | -0.78 | 0.757 | 0.900 | 1.000 | 5583 | tags=53%, list=25%, signal=71% | |
| 351 | NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2 | 65 | -0.22 | -0.78 | 0.857 | 0.898 | 1.000 | 4159 | tags=20%, list=19%, signal=25% | |
| 352 | HUMANCYC_TRIACYLGLYCEROL DEGRADATION | 12 | -0.32 | -0.77 | 0.753 | 0.900 | 1.000 | 2954 | tags=25%, list=13%, signal=29% | |
| 353 | NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY | 62 | -0.21 | -0.76 | 0.880 | 0.921 | 1.000 | 4937 | tags=31%, list=23%, signal=39% | |
| 354 | BIOCARTA_STRESS INDUCTION OF HSP REGULATION | 14 | -0.29 | -0.75 | 0.817 | 0.931 | 1.000 | 4144 | tags=36%, list=19%, signal=44% | |
| 355 | REACTOME_MEMBRANE_TRAFFICKING | 24 | -0.26 | -0.75 | 0.843 | 0.929 | 1.000 | 6074 | tags=54%, list=28%, signal=75% | |
| 356 | NCI_VEGFR3 SIGNALING IN LYMPHATIC ENDOTHELIUM | 24 | -0.25 | -0.75 | 0.829 | 0.927 | 1.000 | 5222 | tags=29%, list=24%, signal=38% | |
| 357 | REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | 14 | -0.28 | -0.74 | 0.797 | 0.930 | 1.000 | 5189 | tags=50%, list=24%, signal=65% | |
| 358 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 14 | -0.28 | -0.73 | 0.817 | 0.937 | 1.000 | 5189 | tags=50%, list=24%, signal=65% | |
| 359 | BIOCARTA_AKT SIGNALING PATHWAY | 14 | -0.29 | -0.73 | 0.819 | 0.935 | 1.000 | 4738 | tags=36%, list=22%, signal=46% | |
| 360 | INOH_SIGNALING WITH WNT (CANONICAL) | 57 | -0.21 | -0.73 | 0.919 | 0.936 | 1.000 | 5867 | tags=33%, list=27%, signal=45% | |
| 361 | REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION | 17 | -0.27 | -0.72 | 0.855 | 0.950 | 1.000 | 3897 | tags=29%, list=18%, signal=36% | |
| 362 | BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY | 28 | -0.24 | -0.71 | 0.888 | 0.948 | 1.000 | 2938 | tags=18%, list=13%, signal=21% | |
| 363 | CELLMAP_HEDGEHOG | 15 | -0.27 | -0.71 | 0.844 | 0.948 | 1.000 | 4922 | tags=33%, list=22%, signal=43% | |
| 364 | REACTOME_CYTOCHROME_P450___ARRANGED_BY_SUBSTRATE_TYPE | 20 | -0.26 | -0.71 | 0.852 | 0.947 | 1.000 | 1400 | tags=10%, list=6%, signal=11% | |
| 365 | BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL | 11 | -0.29 | -0.71 | 0.825 | 0.946 | 1.000 | 3912 | tags=36%, list=18%, signal=44% | |
| 366 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL) | 33 | -0.23 | -0.71 | 0.893 | 0.944 | 1.000 | 3992 | tags=21%, list=18%, signal=26% | |
| 367 | REACTOME_PHASE_1___FUNCTIONALIZATION_OF_COMPOUNDS | 30 | -0.23 | -0.71 | 0.892 | 0.944 | 1.000 | 1740 | tags=10%, list=8%, signal=11% | |
| 368 | NCI_VISUAL SIGNAL TRANSDUCTION: CONES | 16 | -0.28 | -0.71 | 0.840 | 0.941 | 1.000 | 265 | tags=6%, list=1%, signal=6% | |
| 369 | REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION | 20 | -0.25 | -0.70 | 0.870 | 0.948 | 1.000 | 3114 | tags=20%, list=14%, signal=23% | |
| 370 | REACTOME_HORMONE_BIOSYNTHESIS | 31 | -0.22 | -0.69 | 0.891 | 0.955 | 1.000 | 4991 | tags=26%, list=23%, signal=33% | |
| 371 | REACTOME_STEROID_HORMONES | 14 | -0.26 | -0.68 | 0.892 | 0.956 | 1.000 | 4991 | tags=29%, list=23%, signal=37% | |
| 372 | REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION | 14 | -0.27 | -0.68 | 0.857 | 0.954 | 1.000 | 2890 | tags=21%, list=13%, signal=25% | |
| 373 | NCI_EPHB FORWARD SIGNALING | 37 | -0.21 | -0.67 | 0.952 | 0.959 | 1.000 | 3690 | tags=19%, list=17%, signal=23% | |
| 374 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1 | 12 | -0.27 | -0.67 | 0.884 | 0.960 | 1.000 | 5486 | tags=42%, list=25%, signal=56% | |
| 375 | BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY | 32 | -0.21 | -0.66 | 0.927 | 0.964 | 1.000 | 2669 | tags=16%, list=12%, signal=18% | |
| 376 | NCI_LPA4-MEDIATED SIGNALING EVENTS | 14 | -0.26 | -0.66 | 0.913 | 0.965 | 1.000 | 5222 | tags=36%, list=24%, signal=47% | |
| 377 | REACTOME_BIOLOGICAL_OXIDATIONS | 45 | -0.19 | -0.65 | 0.960 | 0.965 | 1.000 | 2788 | tags=13%, list=13%, signal=15% | |
| 378 | NCI_ATYPICAL NF-KAPPAB PATHWAY | 14 | -0.25 | -0.65 | 0.907 | 0.967 | 1.000 | 4738 | tags=36%, list=22%, signal=46% | |
| 379 | BIOCARTA_IL 4 SIGNALING PATHWAY | 11 | -0.26 | -0.63 | 0.915 | 0.975 | 1.000 | 3731 | tags=27%, list=17%, signal=33% | |
| 380 | BIOCARTA_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION | 13 | -0.24 | -0.63 | 0.915 | 0.974 | 1.000 | 7362 | tags=62%, list=34%, signal=93% | |
| 381 | BIOCARTA_VEGF HYPOXIA AND ANGIOGENESIS | 27 | -0.21 | -0.63 | 0.954 | 0.972 | 1.000 | 3858 | tags=19%, list=18%, signal=22% | |
| 382 | INOH_IKK-NF-KAPPAB CASCADE | 12 | -0.25 | -0.62 | 0.911 | 0.972 | 1.000 | 1047 | tags=8%, list=5%, signal=9% | |
| 383 | NCI_VEGFR1 SPECIFIC SIGNALS | 28 | -0.20 | -0.62 | 0.970 | 0.971 | 1.000 | 2185 | tags=11%, list=10%, signal=12% | |
| 384 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS III (VIA DESMOSTEROL) | 13 | -0.24 | -0.61 | 0.943 | 0.971 | 1.000 | 3794 | tags=31%, list=17%, signal=37% | |
| 385 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS I | 13 | -0.24 | -0.61 | 0.930 | 0.972 | 1.000 | 3794 | tags=31%, list=17%, signal=37% | |
| 386 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS II (VIA 24,25-DIHYDROLANOSTEROL) | 13 | -0.24 | -0.60 | 0.952 | 0.974 | 1.000 | 3794 | tags=31%, list=17%, signal=37% | |
| 387 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | 11 | -0.24 | -0.59 | 0.931 | 0.975 | 1.000 | 5984 | tags=36%, list=27%, signal=50% | |
| 388 | INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING | 35 | -0.18 | -0.56 | 0.989 | 0.982 | 1.000 | 17995 | tags=100%, list=82%, signal=556% | |
| 389 | NCI_PDGFR-ALPHA SIGNALING PATHWAY | 21 | -0.20 | -0.55 | 0.973 | 0.982 | 1.000 | 4738 | tags=29%, list=22%, signal=36% | |
| 390 | NETPATH_IL9 | 10 | -0.23 | -0.52 | 0.968 | 0.987 | 1.000 | 2116 | tags=20%, list=10%, signal=22% |