| GS follow link to MSigDB | GS DETAILS | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | RANK AT MAX | LEADING EDGE | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 108 | -0.78 | -1.80 | 0.000 | 0.000 | 0.000 | 1758 | tags=30%, list=9%, signal=33% |
| 2 | NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS | Details ... | 118 | -0.75 | -1.75 | 0.000 | 0.002 | 0.003 | 2003 | tags=32%, list=11%, signal=36% |
| 3 | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) | Details ... | 48 | -0.83 | -1.71 | 0.000 | 0.012 | 0.031 | 2003 | tags=35%, list=11%, signal=40% |
| 4 | NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 48 | -0.82 | -1.70 | 0.000 | 0.010 | 0.035 | 1758 | tags=29%, list=9%, signal=32% |
| 5 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III | Details ... | 30 | -0.90 | -1.70 | 0.000 | 0.008 | 0.035 | 526 | tags=53%, list=3%, signal=55% |
| 6 | NCI_IL23-MEDIATED SIGNALING EVENTS | Details ... | 65 | -0.78 | -1.69 | 0.000 | 0.009 | 0.049 | 1500 | tags=25%, list=8%, signal=27% |
| 7 | NCI_S1P1 PATHWAY | Details ... | 64 | -0.78 | -1.69 | 0.000 | 0.008 | 0.051 | 2381 | tags=28%, list=13%, signal=32% |
| 8 | NCI_IL12-MEDIATED SIGNALING EVENTS | Details ... | 104 | -0.73 | -1.69 | 0.000 | 0.008 | 0.057 | 2337 | tags=31%, list=13%, signal=35% |
| 9 | NETPATH_THROMBOPOIETIN | Details ... | 40 | -0.85 | -1.67 | 0.000 | 0.011 | 0.083 | 2018 | tags=43%, list=11%, signal=48% |
| 10 | NCI_IL6-MEDIATED SIGNALING EVENTS | Details ... | 44 | -0.79 | -1.62 | 0.002 | 0.037 | 0.273 | 2272 | tags=43%, list=12%, signal=49% |
| 11 | NCI_FGF SIGNALING PATHWAY | Details ... | 43 | -0.80 | -1.61 | 0.004 | 0.046 | 0.358 | 1248 | tags=21%, list=7%, signal=22% |
| 12 | NCI_PDGFR-BETA SIGNALING PATHWAY | Details ... | 51 | -0.78 | -1.61 | 0.000 | 0.046 | 0.379 | 2381 | tags=31%, list=13%, signal=36% |
| 13 | NCI_BCR SIGNALING PATHWAY | Details ... | 64 | -0.75 | -1.61 | 0.006 | 0.044 | 0.393 | 2026 | tags=53%, list=11%, signal=59% |
| 14 | NETPATH_BCR | Details ... | 115 | -0.68 | -1.60 | 0.000 | 0.042 | 0.408 | 1552 | tags=41%, list=8%, signal=44% |
| 15 | NCI_EPO SIGNALING PATHWAY | Details ... | 32 | -0.83 | -1.60 | 0.002 | 0.040 | 0.408 | 1476 | tags=34%, list=8%, signal=37% |
| 16 | NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY | Details ... | 119 | -0.67 | -1.59 | 0.000 | 0.052 | 0.521 | 2442 | tags=32%, list=13%, signal=37% |
| 17 | NETPATH_IL2 | Details ... | 61 | -0.74 | -1.59 | 0.000 | 0.049 | 0.521 | 2074 | tags=33%, list=11%, signal=37% |
| 18 | NETPATH_TCR | Details ... | 105 | -0.68 | -1.59 | 0.000 | 0.047 | 0.529 | 2400 | tags=36%, list=13%, signal=41% |
| 19 | NCI_IL1-MEDIATED SIGNALING EVENTS | Details ... | 187 | -0.63 | -1.57 | 0.000 | 0.067 | 0.691 | 2735 | tags=37%, list=15%, signal=43% |
| 20 | NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES | Details ... | 43 | -0.78 | -1.56 | 0.006 | 0.072 | 0.732 | 1758 | tags=23%, list=9%, signal=26% |
| 21 | NCI_THROMBOXANE A2 RECEPTOR SIGNALING | 50 | -0.74 | -1.56 | 0.004 | 0.074 | 0.760 | 2337 | tags=30%, list=13%, signal=34% | |
| 22 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY | 31 | -0.82 | -1.56 | 0.006 | 0.071 | 0.761 | 2052 | tags=45%, list=11%, signal=51% | |
| 23 | NCI_BMP RECEPTOR SIGNALING | 196 | -0.63 | -1.55 | 0.000 | 0.078 | 0.801 | 1824 | tags=26%, list=10%, signal=28% | |
| 24 | NETPATH_IL5 | 31 | -0.80 | -1.55 | 0.006 | 0.077 | 0.809 | 1695 | tags=48%, list=9%, signal=53% | |
| 25 | BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY | 32 | -0.81 | -1.55 | 0.004 | 0.075 | 0.813 | 1695 | tags=28%, list=9%, signal=31% | |
| 26 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL) | 28 | -0.82 | -1.54 | 0.010 | 0.088 | 0.854 | 2092 | tags=25%, list=11%, signal=28% | |
| 27 | NCI_REGULATION OF P38-ALPHA AND P38-BETA | 142 | -0.64 | -1.54 | 0.000 | 0.085 | 0.856 | 1824 | tags=27%, list=10%, signal=29% | |
| 28 | NETPATH_EPO | 39 | -0.76 | -1.52 | 0.009 | 0.108 | 0.930 | 2003 | tags=38%, list=11%, signal=43% | |
| 29 | NCI_CANONICAL NF-KAPPAB PATHWAY | 35 | -0.79 | -1.52 | 0.014 | 0.104 | 0.930 | 1500 | tags=34%, list=8%, signal=37% | |
| 30 | BIOCARTA_MAPKINASE SIGNALING PATHWAY | 54 | -0.71 | -1.52 | 0.013 | 0.111 | 0.938 | 2893 | tags=46%, list=16%, signal=55% | |
| 31 | NCI_IL12 SIGNALING MEDIATED BY STAT4 | 28 | -0.80 | -1.51 | 0.015 | 0.128 | 0.970 | 1160 | tags=29%, list=6%, signal=30% | |
| 32 | NCI_S1P3 PATHWAY | 24 | -0.83 | -1.50 | 0.009 | 0.133 | 0.975 | 2026 | tags=29%, list=11%, signal=33% | |
| 33 | BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY | 32 | -0.79 | -1.50 | 0.013 | 0.130 | 0.975 | 1500 | tags=31%, list=8%, signal=34% | |
| 34 | NCI_IL27-MEDIATED SIGNALING EVENTS | 26 | -0.80 | -1.50 | 0.017 | 0.144 | 0.986 | 2272 | tags=31%, list=12%, signal=35% | |
| 35 | REACTOME_SIGNALLING_BY_NGF | 61 | -0.69 | -1.49 | 0.020 | 0.145 | 0.989 | 2153 | tags=26%, list=12%, signal=30% | |
| 36 | NETPATH_CD40 | 30 | -0.77 | -1.49 | 0.027 | 0.141 | 0.989 | 2672 | tags=47%, list=14%, signal=54% | |
| 37 | NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS | 68 | -0.69 | -1.49 | 0.011 | 0.141 | 0.989 | 1552 | tags=19%, list=8%, signal=21% | |
| 38 | REACTOME_SIGNALING_BY_GPCR | 141 | -0.62 | -1.49 | 0.002 | 0.138 | 0.989 | 1492 | tags=9%, list=8%, signal=9% | |
| 39 | NCI_IL2-MEDIATED SIGNALING EVENTS | 112 | -0.64 | -1.49 | 0.004 | 0.138 | 0.990 | 2074 | tags=33%, list=11%, signal=37% | |
| 40 | NCI_AURORA A SIGNALING | 58 | -0.69 | -1.48 | 0.015 | 0.144 | 0.992 | 1842 | tags=33%, list=10%, signal=36% | |
| 41 | REACTOME_SIGNALING_BY_EGFR | 27 | -0.80 | -1.48 | 0.015 | 0.143 | 0.992 | 2153 | tags=30%, list=12%, signal=33% | |
| 42 | REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | 35 | -0.75 | -1.48 | 0.029 | 0.152 | 0.993 | 1695 | tags=26%, list=9%, signal=28% | |
| 43 | NCI_AMB2 INTEGRIN SIGNALING | 48 | -0.71 | -1.47 | 0.007 | 0.158 | 0.995 | 2694 | tags=27%, list=14%, signal=32% | |
| 44 | NCI_EPHA FORWARD SIGNALING | 30 | -0.77 | -1.47 | 0.027 | 0.159 | 0.997 | 2908 | tags=27%, list=16%, signal=32% | |
| 45 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I | 90 | -0.64 | -1.47 | 0.012 | 0.157 | 0.997 | 1023 | tags=27%, list=5%, signal=28% | |
| 46 | INOH_B CELL RECEPTOR SIGNALING PATHWAY | 68 | -0.67 | -1.47 | 0.017 | 0.154 | 0.997 | 2049 | tags=34%, list=11%, signal=38% | |
| 47 | NETPATH_IL-7 | 16 | -0.88 | -1.47 | 0.021 | 0.152 | 0.997 | 500 | tags=25%, list=3%, signal=26% | |
| 48 | NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING | 266 | -0.58 | -1.47 | 0.000 | 0.156 | 0.998 | 2536 | tags=29%, list=14%, signal=33% | |
| 49 | BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING | 31 | -0.76 | -1.47 | 0.029 | 0.153 | 0.998 | 2026 | tags=39%, list=11%, signal=43% | |
| 50 | INOH_T CELL RECEPTOR SIGNALING PATHWAY | 51 | -0.71 | -1.47 | 0.011 | 0.154 | 0.998 | 2382 | tags=51%, list=13%, signal=58% | |
| 51 | NCI_P38 MAPK SIGNALING PATHWAY | 162 | -0.61 | -1.46 | 0.002 | 0.161 | 0.999 | 1824 | tags=26%, list=10%, signal=28% | |
| 52 | NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY | 32 | -0.77 | -1.46 | 0.036 | 0.160 | 0.999 | 1758 | tags=34%, list=9%, signal=38% | |
| 53 | INOH_SIGNALING WITH WNT (MAMMAL) | 52 | -0.71 | -1.46 | 0.016 | 0.157 | 0.999 | 1447 | tags=15%, list=8%, signal=17% | |
| 54 | NCI_P75(NTR)-MEDIATED SIGNALING | 157 | -0.61 | -1.46 | 0.004 | 0.158 | 0.999 | 2153 | tags=29%, list=12%, signal=33% | |
| 55 | NCI_TNF RECEPTOR SIGNALING PATHWAY | 244 | -0.57 | -1.46 | 0.000 | 0.157 | 0.999 | 2710 | tags=34%, list=15%, signal=39% | |
| 56 | BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY | 45 | -0.72 | -1.46 | 0.020 | 0.155 | 0.999 | 2337 | tags=44%, list=13%, signal=51% | |
| 57 | BIOCARTA_TPO SIGNALING PATHWAY | 22 | -0.81 | -1.46 | 0.023 | 0.155 | 0.999 | 1842 | tags=36%, list=10%, signal=40% | |
| 58 | BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY | 19 | -0.84 | -1.46 | 0.022 | 0.153 | 0.999 | 2473 | tags=37%, list=13%, signal=42% | |
| 59 | BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK) | 18 | -0.85 | -1.45 | 0.031 | 0.153 | 0.999 | 1403 | tags=33%, list=8%, signal=36% | |
| 60 | NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 56 | -0.68 | -1.45 | 0.026 | 0.153 | 0.999 | 1842 | tags=34%, list=10%, signal=38% | |
| 61 | BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES | 25 | -0.79 | -1.45 | 0.037 | 0.158 | 1.000 | 2042 | tags=52%, list=11%, signal=58% | |
| 62 | BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 27 | -0.78 | -1.45 | 0.029 | 0.156 | 1.000 | 1776 | tags=37%, list=10%, signal=41% | |
| 63 | BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS | 16 | -0.86 | -1.45 | 0.023 | 0.158 | 1.000 | 2042 | tags=56%, list=11%, signal=63% | |
| 64 | NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE | 67 | -0.67 | -1.45 | 0.034 | 0.158 | 1.000 | 1842 | tags=30%, list=10%, signal=33% | |
| 65 | NCI_OSTEOPONTIN-MEDIATED EVENTS | 29 | -0.75 | -1.45 | 0.029 | 0.156 | 1.000 | 1222 | tags=38%, list=7%, signal=41% | |
| 66 | NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES | 78 | -0.66 | -1.45 | 0.013 | 0.154 | 1.000 | 1552 | tags=26%, list=8%, signal=28% | |
| 67 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL) | 31 | -0.76 | -1.44 | 0.038 | 0.163 | 1.000 | 2477 | tags=29%, list=13%, signal=33% | |
| 68 | BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES | 15 | -0.86 | -1.44 | 0.033 | 0.167 | 1.000 | 1695 | tags=47%, list=9%, signal=51% | |
| 69 | BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY | 14 | -0.89 | -1.44 | 0.019 | 0.167 | 1.000 | 830 | tags=21%, list=4%, signal=22% | |
| 70 | NCI_S1P2 PATHWAY | 21 | -0.81 | -1.44 | 0.044 | 0.165 | 1.000 | 2026 | tags=33%, list=11%, signal=37% | |
| 71 | NETPATH_IFN-ALPHA | 43 | -0.70 | -1.43 | 0.028 | 0.168 | 1.000 | 2500 | tags=42%, list=13%, signal=48% | |
| 72 | NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5 | 29 | -0.77 | -1.43 | 0.050 | 0.179 | 1.000 | 2382 | tags=31%, list=13%, signal=36% | |
| 73 | BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY | 24 | -0.80 | -1.43 | 0.035 | 0.181 | 1.000 | 1695 | tags=25%, list=9%, signal=27% | |
| 74 | CELLMAP_KITRECEPTOR | 49 | -0.69 | -1.43 | 0.029 | 0.179 | 1.000 | 1932 | tags=27%, list=10%, signal=30% | |
| 75 | NCI_S1P4 PATHWAY | 11 | -0.91 | -1.42 | 0.017 | 0.180 | 1.000 | 1222 | tags=27%, list=7%, signal=29% | |
| 76 | BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS | 28 | -0.75 | -1.42 | 0.043 | 0.183 | 1.000 | 2042 | tags=46%, list=11%, signal=52% | |
| 77 | REACTOME_SEMAPHORIN_INTERACTIONS | 30 | -0.76 | -1.42 | 0.041 | 0.183 | 1.000 | 2052 | tags=23%, list=11%, signal=26% | |
| 78 | INOH_IKK-NF-KAPPAB CASCADE | 12 | -0.87 | -1.42 | 0.040 | 0.185 | 1.000 | 1552 | tags=50%, list=8%, signal=55% | |
| 79 | REACTOME_COMMON_PATHWAY | 11 | -0.88 | -1.42 | 0.048 | 0.183 | 1.000 | 352 | tags=9%, list=2%, signal=9% | |
| 80 | NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR | 19 | -0.82 | -1.42 | 0.036 | 0.185 | 1.000 | 695 | tags=11%, list=4%, signal=11% | |
| 81 | INOH_SIGNALING WITH WNT (CANONICAL) | 55 | -0.66 | -1.42 | 0.033 | 0.184 | 1.000 | 2477 | tags=20%, list=13%, signal=23% | |
| 82 | REACTOME_SIGNALING_IN_IMMUNE_SYSTEM | 136 | -0.59 | -1.42 | 0.002 | 0.182 | 1.000 | 1241 | tags=16%, list=7%, signal=17% | |
| 83 | BIOCARTA_P38 MAPK SIGNALING PATHWAY | 28 | -0.77 | -1.42 | 0.038 | 0.182 | 1.000 | 2041 | tags=46%, list=11%, signal=52% | |
| 84 | REACTOME_PLATELET_ACTIVATION | 69 | -0.65 | -1.41 | 0.024 | 0.183 | 1.000 | 1403 | tags=16%, list=8%, signal=17% | |
| 85 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS) | 16 | -0.83 | -1.41 | 0.050 | 0.184 | 1.000 | 988 | tags=13%, list=5%, signal=13% | |
| 86 | NCI_CLASS I PI3K SIGNALING EVENTS | 217 | -0.56 | -1.41 | 0.002 | 0.192 | 1.000 | 2026 | tags=31%, list=11%, signal=35% | |
| 87 | INOH_SIGNALING WITH WNT (XENOPUS) | 16 | -0.83 | -1.41 | 0.069 | 0.192 | 1.000 | 988 | tags=13%, list=5%, signal=13% | |
| 88 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA | 56 | -0.66 | -1.40 | 0.044 | 0.199 | 1.000 | 2153 | tags=36%, list=12%, signal=40% | |
| 89 | BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY | 24 | -0.76 | -1.40 | 0.052 | 0.207 | 1.000 | 2339 | tags=50%, list=13%, signal=57% | |
| 90 | INOH_MAMMALIAN NOTCH SIGNALING PATHWAY | 22 | -0.78 | -1.40 | 0.047 | 0.205 | 1.000 | 1979 | tags=41%, list=11%, signal=46% | |
| 91 | INOH_PHOSPHOLIPASE C GAMMA SIGNALING | 48 | -0.68 | -1.40 | 0.044 | 0.207 | 1.000 | 2382 | tags=48%, list=13%, signal=55% | |
| 92 | REACTOME_SIGNALLING_TO_ERKS | 13 | -0.86 | -1.39 | 0.039 | 0.209 | 1.000 | 2153 | tags=46%, list=12%, signal=52% | |
| 93 | INOH_SIGNALING WITHOUT WNT (MAMMAL) | 24 | -0.77 | -1.39 | 0.056 | 0.217 | 1.000 | 2092 | tags=29%, list=11%, signal=33% | |
| 94 | NETPATH_BDNF | 31 | -0.72 | -1.39 | 0.049 | 0.222 | 1.000 | 2938 | tags=32%, list=16%, signal=38% | |
| 95 | BIOCARTA_RAS SIGNALING PATHWAY | 19 | -0.79 | -1.39 | 0.087 | 0.222 | 1.000 | 2166 | tags=42%, list=12%, signal=48% | |
| 96 | INOH_NOTCH SECRETORY PATHWAY | 26 | -0.75 | -1.39 | 0.072 | 0.222 | 1.000 | 1979 | tags=31%, list=11%, signal=34% | |
| 97 | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY | 132 | -0.58 | -1.38 | 0.011 | 0.222 | 1.000 | 2759 | tags=35%, list=15%, signal=41% | |
| 98 | REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL | 21 | -0.77 | -1.38 | 0.077 | 0.222 | 1.000 | 1695 | tags=24%, list=9%, signal=26% | |
| 99 | INOH_CANONICAL NOTCH SIGNALING PATHWAY | 26 | -0.75 | -1.38 | 0.055 | 0.220 | 1.000 | 1979 | tags=31%, list=11%, signal=34% | |
| 100 | BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY | 17 | -0.81 | -1.38 | 0.064 | 0.222 | 1.000 | 1603 | tags=24%, list=9%, signal=26% | |
| 101 | NCI_IFN-GAMMA PATHWAY | 331 | -0.53 | -1.38 | 0.000 | 0.222 | 1.000 | 2042 | tags=24%, list=11%, signal=26% | |
| 102 | INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL) | 19 | -0.78 | -1.38 | 0.059 | 0.222 | 1.000 | 2092 | tags=32%, list=11%, signal=36% | |
| 103 | NCI_TGF-BETA RECEPTOR SIGNALING | 258 | -0.54 | -1.38 | 0.000 | 0.221 | 1.000 | 2042 | tags=24%, list=11%, signal=27% | |
| 104 | REACTOME_SIGNALLING_TO_RAS | 12 | -0.86 | -1.38 | 0.049 | 0.219 | 1.000 | 2153 | tags=50%, list=12%, signal=57% | |
| 105 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 12 | -0.87 | -1.38 | 0.065 | 0.220 | 1.000 | 1837 | tags=50%, list=10%, signal=55% | |
| 106 | REACTOME_TCR_SIGNALING | 32 | -0.72 | -1.38 | 0.063 | 0.220 | 1.000 | 1022 | tags=25%, list=5%, signal=26% | |
| 107 | BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC | 22 | -0.77 | -1.37 | 0.081 | 0.222 | 1.000 | 1776 | tags=36%, list=10%, signal=40% | |
| 108 | NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING | 258 | -0.54 | -1.37 | 0.002 | 0.222 | 1.000 | 2042 | tags=24%, list=11%, signal=27% | |
| 109 | NCI_VEGFR3 SIGNALING IN LYMPHATIC ENDOTHELIUM | 22 | -0.77 | -1.37 | 0.070 | 0.220 | 1.000 | 1776 | tags=23%, list=10%, signal=25% | |
| 110 | BIOCARTA_PDGF SIGNALING PATHWAY | 24 | -0.77 | -1.37 | 0.081 | 0.219 | 1.000 | 2017 | tags=46%, list=11%, signal=51% | |
| 111 | BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY | 29 | -0.72 | -1.37 | 0.077 | 0.224 | 1.000 | 2330 | tags=31%, list=13%, signal=35% | |
| 112 | BIOCARTA_EGF SIGNALING PATHWAY | 18 | -0.79 | -1.37 | 0.079 | 0.226 | 1.000 | 2017 | tags=44%, list=11%, signal=50% | |
| 113 | NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING | 258 | -0.54 | -1.37 | 0.003 | 0.227 | 1.000 | 2042 | tags=24%, list=11%, signal=27% | |
| 114 | NCI_ENDOTHELINS | 147 | -0.56 | -1.37 | 0.014 | 0.226 | 1.000 | 1758 | tags=20%, list=9%, signal=22% | |
| 115 | REACTOME_SHC_RELATED_EVENTS | 10 | -0.86 | -1.37 | 0.076 | 0.226 | 1.000 | 2153 | tags=50%, list=12%, signal=57% | |
| 116 | NCI_IL4-MEDIATED SIGNALING EVENTS | 58 | -0.63 | -1.37 | 0.044 | 0.225 | 1.000 | 1548 | tags=17%, list=8%, signal=19% | |
| 117 | INOH_NOTCH SECRETORY PATHWAY (MAMMAL) | 22 | -0.78 | -1.36 | 0.056 | 0.227 | 1.000 | 1979 | tags=41%, list=11%, signal=46% | |
| 118 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G) | 11 | -0.87 | -1.36 | 0.077 | 0.237 | 1.000 | 1250 | tags=36%, list=7%, signal=39% | |
| 119 | BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART | 42 | -0.68 | -1.36 | 0.057 | 0.236 | 1.000 | 1883 | tags=21%, list=10%, signal=24% | |
| 120 | BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING | 34 | -0.70 | -1.36 | 0.067 | 0.240 | 1.000 | 1965 | tags=26%, list=11%, signal=30% | |
| 121 | REACTOME_OPIOID_SIGNALLING | 22 | -0.77 | -1.35 | 0.085 | 0.240 | 1.000 | 3091 | tags=36%, list=17%, signal=44% | |
| 122 | INOH_IL-1_SIGNALING(THROUGH_IKK-NFKB_CASCADE)(CANONICAL) | 23 | -0.74 | -1.35 | 0.127 | 0.240 | 1.000 | 1022 | tags=26%, list=5%, signal=28% | |
| 123 | BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY | 13 | -0.84 | -1.35 | 0.078 | 0.245 | 1.000 | 2052 | tags=46%, list=11%, signal=52% | |
| 124 | INOH_SIGNALING WITHOUT WNT (CANONICAL) | 27 | -0.71 | -1.34 | 0.092 | 0.263 | 1.000 | 2477 | tags=33%, list=13%, signal=38% | |
| 125 | INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING | 36 | -0.67 | -1.34 | 0.085 | 0.274 | 1.000 | 3673 | tags=22%, list=20%, signal=28% | |
| 126 | BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY | 27 | -0.71 | -1.33 | 0.082 | 0.275 | 1.000 | 2017 | tags=26%, list=11%, signal=29% | |
| 127 | BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY | 12 | -0.84 | -1.33 | 0.100 | 0.274 | 1.000 | 1695 | tags=25%, list=9%, signal=27% | |
| 128 | NCI_LPA RECEPTOR MEDIATED EVENTS | 91 | -0.59 | -1.33 | 0.043 | 0.276 | 1.000 | 1552 | tags=22%, list=8%, signal=24% | |
| 129 | NETPATH_IL9 | 11 | -0.84 | -1.33 | 0.081 | 0.277 | 1.000 | 2382 | tags=36%, list=13%, signal=42% | |
| 130 | BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE | 13 | -0.83 | -1.33 | 0.108 | 0.278 | 1.000 | 2442 | tags=46%, list=13%, signal=53% | |
| 131 | BIOCARTA_EPO SIGNALING PATHWAY | 11 | -0.83 | -1.33 | 0.128 | 0.282 | 1.000 | 1248 | tags=18%, list=7%, signal=19% | |
| 132 | BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY | 11 | -0.84 | -1.33 | 0.113 | 0.284 | 1.000 | 2272 | tags=45%, list=12%, signal=52% | |
| 133 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 18 | -0.76 | -1.32 | 0.113 | 0.283 | 1.000 | 1695 | tags=22%, list=9%, signal=24% | |
| 134 | BIOCARTA_IL-7 SIGNAL TRANSDUCTION | 14 | -0.81 | -1.32 | 0.119 | 0.293 | 1.000 | 2382 | tags=36%, list=13%, signal=41% | |
| 135 | REACTOME_PLC_BETA_MEDIATED_EVENTS | 10 | -0.86 | -1.32 | 0.093 | 0.298 | 1.000 | 1335 | tags=20%, list=7%, signal=22% | |
| 136 | REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING | 10 | -0.86 | -1.32 | 0.095 | 0.297 | 1.000 | 2153 | tags=50%, list=12%, signal=57% | |
| 137 | BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR | 17 | -0.78 | -1.32 | 0.116 | 0.297 | 1.000 | 2026 | tags=29%, list=11%, signal=33% | |
| 138 | NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING | 88 | -0.58 | -1.32 | 0.038 | 0.297 | 1.000 | 2153 | tags=32%, list=12%, signal=36% | |
| 139 | NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING | 37 | -0.65 | -1.31 | 0.079 | 0.299 | 1.000 | 2002 | tags=24%, list=11%, signal=27% | |
| 140 | NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY | 33 | -0.68 | -1.31 | 0.087 | 0.298 | 1.000 | 2003 | tags=33%, list=11%, signal=37% | |
| 141 | BIOCARTA_CXCR4 SIGNALING PATHWAY | 11 | -0.85 | -1.31 | 0.102 | 0.296 | 1.000 | 124 | tags=9%, list=1%, signal=9% | |
| 142 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 18 | -0.76 | -1.31 | 0.135 | 0.295 | 1.000 | 1695 | tags=22%, list=9%, signal=24% | |
| 143 | BIOCARTA_KERATINOCYTE DIFFERENTIATION | 51 | -0.63 | -1.31 | 0.078 | 0.294 | 1.000 | 2054 | tags=33%, list=11%, signal=37% | |
| 144 | BIOCARTA_SEGMENTATION CLOCK | 22 | -0.72 | -1.31 | 0.126 | 0.295 | 1.000 | 2046 | tags=18%, list=11%, signal=20% | |
| 145 | NCI_GLYPICAN 1 NETWORK | 380 | -0.50 | -1.31 | 0.000 | 0.293 | 1.000 | 2042 | tags=26%, list=11%, signal=29% | |
| 146 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE) | 185 | -0.53 | -1.31 | 0.013 | 0.292 | 1.000 | 2072 | tags=10%, list=11%, signal=11% | |
| 147 | NCI_IL2 SIGNALING EVENTS MEDIATED BY PI3K | 67 | -0.61 | -1.31 | 0.070 | 0.295 | 1.000 | 2382 | tags=36%, list=13%, signal=41% | |
| 148 | NCI_GLYPICAN PATHWAY | 416 | -0.49 | -1.31 | 0.000 | 0.294 | 1.000 | 2042 | tags=25%, list=11%, signal=27% | |
| 149 | REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING | 11 | -0.85 | -1.30 | 0.103 | 0.301 | 1.000 | 2153 | tags=45%, list=12%, signal=51% | |
| 150 | BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML | 10 | -0.83 | -1.30 | 0.151 | 0.305 | 1.000 | 1527 | tags=40%, list=8%, signal=44% | |
| 151 | NCI_CELLULAR ROLES OF ANTHRAX TOXIN | 15 | -0.79 | -1.30 | 0.146 | 0.313 | 1.000 | 2042 | tags=40%, list=11%, signal=45% | |
| 152 | REACTOME_G_PROTEIN_MEDIATED_EVENTS | 11 | -0.83 | -1.30 | 0.118 | 0.312 | 1.000 | 1335 | tags=18%, list=7%, signal=20% | |
| 153 | BIOCARTA_CELL CYCLE: G2/M CHECKPOINT | 19 | -0.74 | -1.29 | 0.140 | 0.324 | 1.000 | 499 | tags=21%, list=3%, signal=22% | |
| 154 | NCI_TRAIL SIGNALING PATHWAY | 275 | -0.50 | -1.29 | 0.015 | 0.329 | 1.000 | 2054 | tags=28%, list=11%, signal=31% | |
| 155 | BIOCARTA_RB TUMOR SUPPRESSOR/CHECKPOINT SIGNALING IN RESPONSE TO DNA DAMAGE | 12 | -0.83 | -1.28 | 0.130 | 0.332 | 1.000 | 1138 | tags=25%, list=6%, signal=27% | |
| 156 | NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY | 22 | -0.71 | -1.28 | 0.140 | 0.331 | 1.000 | 1758 | tags=27%, list=9%, signal=30% | |
| 157 | INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL) | 22 | -0.72 | -1.27 | 0.134 | 0.354 | 1.000 | 2477 | tags=36%, list=13%, signal=42% | |
| 158 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH LPS, TLR4, MYD88, IRAK, TAK1 AND IKK-NF-KAPPAB CASCADE)(CANONICAL) | 22 | -0.72 | -1.27 | 0.144 | 0.356 | 1.000 | 1022 | tags=27%, list=5%, signal=29% | |
| 159 | INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL) | 189 | -0.50 | -1.27 | 0.031 | 0.359 | 1.000 | 2072 | tags=9%, list=11%, signal=10% | |
| 160 | BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION | 13 | -0.79 | -1.27 | 0.173 | 0.361 | 1.000 | 1695 | tags=31%, list=9%, signal=34% | |
| 161 | INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS) | 11 | -0.80 | -1.26 | 0.184 | 0.365 | 1.000 | 1695 | tags=45%, list=9%, signal=50% | |
| 162 | REACTOME_PLATELET_ACTIVATION_TRIGGERS | 24 | -0.69 | -1.26 | 0.134 | 0.368 | 1.000 | 1403 | tags=38%, list=8%, signal=41% | |
| 163 | NCI_EPHRINB-EPHB PATHWAY | 52 | -0.60 | -1.26 | 0.118 | 0.368 | 1.000 | 2337 | tags=31%, list=13%, signal=35% | |
| 164 | BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY | 34 | -0.65 | -1.26 | 0.137 | 0.366 | 1.000 | 2192 | tags=44%, list=12%, signal=50% | |
| 165 | BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE | 18 | -0.74 | -1.26 | 0.161 | 0.367 | 1.000 | 1500 | tags=22%, list=8%, signal=24% | |
| 166 | REACTOME_AXON_GUIDANCE | 56 | -0.59 | -1.26 | 0.101 | 0.371 | 1.000 | 2240 | tags=25%, list=12%, signal=28% | |
| 167 | BIOCARTA_IL 3 SIGNALING PATHWAY | 11 | -0.81 | -1.25 | 0.195 | 0.376 | 1.000 | 1248 | tags=18%, list=7%, signal=19% | |
| 168 | BIOCARTA_EICOSANOID METABOLISM | 19 | -0.72 | -1.25 | 0.194 | 0.379 | 1.000 | 1229 | tags=16%, list=7%, signal=17% | |
| 169 | BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF | 17 | -0.74 | -1.25 | 0.162 | 0.380 | 1.000 | 2284 | tags=41%, list=12%, signal=47% | |
| 170 | BIOCARTA_BCR SIGNALING PATHWAY | 29 | -0.67 | -1.25 | 0.157 | 0.382 | 1.000 | 2026 | tags=55%, list=11%, signal=62% | |
| 171 | REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 15 | -0.76 | -1.25 | 0.199 | 0.384 | 1.000 | 1695 | tags=20%, list=9%, signal=22% | |
| 172 | BIOCARTA_TRKA RECEPTOR SIGNALING PATHWAY | 11 | -0.81 | -1.24 | 0.197 | 0.386 | 1.000 | 1500 | tags=27%, list=8%, signal=30% | |
| 173 | NETPATH_GDNF | 29 | -0.66 | -1.24 | 0.179 | 0.384 | 1.000 | 1842 | tags=21%, list=10%, signal=23% | |
| 174 | INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE | 36 | -0.63 | -1.24 | 0.153 | 0.393 | 1.000 | 2382 | tags=47%, list=13%, signal=54% | |
| 175 | REACTOME_SYNAPTIC_TRANSMISSION | 42 | -0.61 | -1.24 | 0.153 | 0.394 | 1.000 | 1695 | tags=17%, list=9%, signal=18% | |
| 176 | REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE | 14 | -0.76 | -1.24 | 0.216 | 0.392 | 1.000 | 1160 | tags=36%, list=6%, signal=38% | |
| 177 | BIOCARTA_IL 2 SIGNALING PATHWAY | 14 | -0.75 | -1.24 | 0.210 | 0.391 | 1.000 | 2382 | tags=43%, list=13%, signal=49% | |
| 178 | INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR) | 14 | -0.75 | -1.23 | 0.215 | 0.408 | 1.000 | 2620 | tags=50%, list=14%, signal=58% | |
| 179 | BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION | 16 | -0.73 | -1.23 | 0.182 | 0.406 | 1.000 | 2314 | tags=31%, list=12%, signal=36% | |
| 180 | BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R | 34 | -0.64 | -1.23 | 0.154 | 0.406 | 1.000 | 2042 | tags=38%, list=11%, signal=43% | |
| 181 | INOH_PLC BETA SIGNALING | 18 | -0.73 | -1.23 | 0.210 | 0.407 | 1.000 | 2620 | tags=39%, list=14%, signal=45% | |
| 182 | REACTOME_INNATE_IMMUNITY_SIGNALING | 40 | -0.62 | -1.23 | 0.185 | 0.405 | 1.000 | 1241 | tags=20%, list=7%, signal=21% | |
| 183 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 41 | -0.61 | -1.23 | 0.160 | 0.404 | 1.000 | 1695 | tags=17%, list=9%, signal=19% | |
| 184 | BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES | 28 | -0.65 | -1.22 | 0.193 | 0.406 | 1.000 | 1695 | tags=21%, list=9%, signal=24% | |
| 185 | BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT | 15 | -0.71 | -1.22 | 0.216 | 0.405 | 1.000 | 2272 | tags=40%, list=12%, signal=46% | |
| 186 | INOH_JNK CASCADE | 16 | -0.72 | -1.22 | 0.227 | 0.410 | 1.000 | 2042 | tags=38%, list=11%, signal=42% | |
| 187 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II | 22 | -0.68 | -1.22 | 0.187 | 0.411 | 1.000 | 2712 | tags=36%, list=15%, signal=43% | |
| 188 | BIOCARTA_NF-KB SIGNALING PATHWAY | 20 | -0.69 | -1.22 | 0.200 | 0.410 | 1.000 | 1022 | tags=25%, list=5%, signal=26% | |
| 189 | INOH_MAMMALIAN WNT SIGNALING PATHWAY | 70 | -0.55 | -1.22 | 0.121 | 0.408 | 1.000 | 1447 | tags=11%, list=8%, signal=12% | |
| 190 | NCI_SIGNALING EVENTS MEDIATED BY PTP1B | 46 | -0.59 | -1.22 | 0.147 | 0.407 | 1.000 | 2381 | tags=15%, list=13%, signal=17% | |
| 191 | NCI_SIGNALING BY AURORA KINASES | 85 | -0.53 | -1.22 | 0.097 | 0.408 | 1.000 | 1619 | tags=25%, list=9%, signal=27% | |
| 192 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) | 26 | -0.65 | -1.21 | 0.191 | 0.412 | 1.000 | 2382 | tags=58%, list=13%, signal=66% | |
| 193 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE) | 197 | -0.49 | -1.21 | 0.062 | 0.412 | 1.000 | 2394 | tags=11%, list=13%, signal=13% | |
| 194 | BIOCARTA_BONE REMODELING | 15 | -0.73 | -1.21 | 0.241 | 0.411 | 1.000 | 884 | tags=20%, list=5%, signal=21% | |
| 195 | BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE | 26 | -0.66 | -1.21 | 0.197 | 0.412 | 1.000 | 2042 | tags=38%, list=11%, signal=43% | |
| 196 | REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | 15 | -0.73 | -1.21 | 0.226 | 0.410 | 1.000 | 2433 | tags=47%, list=13%, signal=54% | |
| 197 | REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | 15 | -0.73 | -1.21 | 0.251 | 0.415 | 1.000 | 678 | tags=13%, list=4%, signal=14% | |
| 198 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 22 | -0.69 | -1.21 | 0.210 | 0.414 | 1.000 | 693 | tags=14%, list=4%, signal=14% | |
| 199 | NETPATH_IL4 | 42 | -0.61 | -1.21 | 0.169 | 0.414 | 1.000 | 2017 | tags=36%, list=11%, signal=40% | |
| 200 | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING | 32 | -0.62 | -1.21 | 0.196 | 0.414 | 1.000 | 1695 | tags=19%, list=9%, signal=21% | |
| 201 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN) | 175 | -0.48 | -1.20 | 0.076 | 0.419 | 1.000 | 2394 | tags=9%, list=13%, signal=10% | |
| 202 | NETPATH_IL3 | 64 | -0.56 | -1.20 | 0.139 | 0.421 | 1.000 | 2153 | tags=33%, list=12%, signal=37% | |
| 203 | BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS | 15 | -0.73 | -1.20 | 0.237 | 0.423 | 1.000 | 1695 | tags=33%, list=9%, signal=37% | |
| 204 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH JNK CASCADE)(CANONICAL) | 23 | -0.65 | -1.20 | 0.218 | 0.423 | 1.000 | 2192 | tags=39%, list=12%, signal=44% | |
| 205 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | 16 | -0.71 | -1.20 | 0.245 | 0.423 | 1.000 | 2337 | tags=13%, list=13%, signal=14% | |
| 206 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE | 12 | -0.76 | -1.20 | 0.268 | 0.422 | 1.000 | 1160 | tags=33%, list=6%, signal=36% | |
| 207 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 15 | -0.73 | -1.20 | 0.259 | 0.421 | 1.000 | 2433 | tags=47%, list=13%, signal=54% | |
| 208 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP) | 175 | -0.48 | -1.19 | 0.071 | 0.424 | 1.000 | 2394 | tags=9%, list=13%, signal=10% | |
| 209 | BIOCARTA_CERAMIDE SIGNALING PATHWAY | 48 | -0.58 | -1.19 | 0.174 | 0.429 | 1.000 | 2442 | tags=33%, list=13%, signal=38% | |
| 210 | REACTOME_DOWNSTREAM_TCR_SIGNALING | 19 | -0.68 | -1.19 | 0.237 | 0.428 | 1.000 | 1022 | tags=32%, list=5%, signal=33% | |
| 211 | BIOCARTA_EFFECTS OF CALCINEURIN IN KERATINOCYTE DIFFERENTIATION | 12 | -0.75 | -1.19 | 0.293 | 0.431 | 1.000 | 1883 | tags=50%, list=10%, signal=56% | |
| 212 | BIOCARTA_DOUBLE STRANDED RNA INDUCED GENE EXPRESSION | 12 | -0.75 | -1.19 | 0.273 | 0.431 | 1.000 | 884 | tags=25%, list=5%, signal=26% | |
| 213 | NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS | 229 | -0.47 | -1.18 | 0.063 | 0.436 | 1.000 | 2423 | tags=25%, list=13%, signal=29% | |
| 214 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE) | 19 | -0.68 | -1.18 | 0.234 | 0.437 | 1.000 | 2192 | tags=53%, list=12%, signal=60% | |
| 215 | INOH_IL-1_SIGNALING(THROUGH_JNK_CASCADE)(CANONICAL) | 24 | -0.65 | -1.18 | 0.243 | 0.435 | 1.000 | 2042 | tags=33%, list=11%, signal=37% | |
| 216 | NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING | 44 | -0.58 | -1.18 | 0.196 | 0.437 | 1.000 | 2026 | tags=23%, list=11%, signal=25% | |
| 217 | REACTOME_TOLL_RECEPTOR_CASCADES | 26 | -0.65 | -1.18 | 0.234 | 0.439 | 1.000 | 1241 | tags=31%, list=7%, signal=33% | |
| 218 | BIOCARTA_ESTROGEN RESPONSIVE PROTEIN EFP CONTROLS CELL CYCLE AND BREAST TUMORS GROWTH | 13 | -0.73 | -1.18 | 0.288 | 0.441 | 1.000 | 36 | tags=8%, list=0%, signal=8% | |
| 219 | NCI_ATYPICAL NF-KAPPAB PATHWAY | 14 | -0.73 | -1.18 | 0.272 | 0.439 | 1.000 | 2500 | tags=50%, list=13%, signal=58% | |
| 220 | REACTOME_SIGNALING_BY_PDGF | 21 | -0.67 | -1.17 | 0.237 | 0.440 | 1.000 | 2240 | tags=33%, list=12%, signal=38% | |
| 221 | NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET) | 142 | -0.50 | -1.17 | 0.135 | 0.439 | 1.000 | 2381 | tags=32%, list=13%, signal=37% | |
| 222 | REACTOME_HEMOSTASIS | 147 | -0.49 | -1.17 | 0.130 | 0.446 | 1.000 | 1403 | tags=14%, list=8%, signal=15% | |
| 223 | REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION | 17 | -0.68 | -1.17 | 0.257 | 0.445 | 1.000 | 2240 | tags=41%, list=12%, signal=47% | |
| 224 | REACTOME_FORMATION_OF_PLATELET_PLUG | 81 | -0.52 | -1.17 | 0.167 | 0.449 | 1.000 | 1403 | tags=15%, list=8%, signal=16% | |
| 225 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE) | 32 | -0.60 | -1.16 | 0.230 | 0.450 | 1.000 | 2382 | tags=50%, list=13%, signal=57% | |
| 226 | NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS | 150 | -0.49 | -1.16 | 0.124 | 0.450 | 1.000 | 2534 | tags=33%, list=14%, signal=38% | |
| 227 | NCI_EPHB FORWARD SIGNALING | 35 | -0.60 | -1.16 | 0.227 | 0.448 | 1.000 | 2258 | tags=31%, list=12%, signal=36% | |
| 228 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 13 | -0.72 | -1.16 | 0.315 | 0.447 | 1.000 | 1107 | tags=38%, list=6%, signal=41% | |
| 229 | BIOCARTA_TNFR2 SIGNALING PATHWAY | 12 | -0.72 | -1.16 | 0.315 | 0.448 | 1.000 | 969 | tags=42%, list=5%, signal=44% | |
| 230 | NCI_FOXO FAMILY SIGNALING | 43 | -0.58 | -1.16 | 0.186 | 0.449 | 1.000 | 1527 | tags=21%, list=8%, signal=23% | |
| 231 | NCI_ARF6 SIGNALING EVENTS | 113 | -0.50 | -1.16 | 0.162 | 0.455 | 1.000 | 2534 | tags=29%, list=14%, signal=34% | |
| 232 | BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL | 11 | -0.74 | -1.16 | 0.306 | 0.454 | 1.000 | 2314 | tags=45%, list=12%, signal=52% | |
| 233 | INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY | 196 | -0.47 | -1.15 | 0.120 | 0.457 | 1.000 | 2382 | tags=26%, list=13%, signal=29% | |
| 234 | NCI_ARF6 TRAFFICKING EVENTS | 113 | -0.50 | -1.15 | 0.177 | 0.460 | 1.000 | 2534 | tags=29%, list=14%, signal=34% | |
| 235 | NCI_INSULIN PATHWAY | 113 | -0.50 | -1.15 | 0.167 | 0.461 | 1.000 | 2534 | tags=29%, list=14%, signal=34% | |
| 236 | NCI_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION | 10 | -0.75 | -1.15 | 0.348 | 0.461 | 1.000 | 821 | tags=20%, list=4%, signal=21% | |
| 237 | BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY | 20 | -0.64 | -1.15 | 0.285 | 0.460 | 1.000 | 1695 | tags=30%, list=9%, signal=33% | |
| 238 | REACTOME_PLATELET_DEGRANULATION_ | 42 | -0.57 | -1.15 | 0.250 | 0.458 | 1.000 | 2847 | tags=12%, list=15%, signal=14% | |
| 239 | CELLMAP_EGFR1 | 117 | -0.49 | -1.15 | 0.169 | 0.456 | 1.000 | 2240 | tags=30%, list=12%, signal=34% | |
| 240 | REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | 20 | -0.67 | -1.15 | 0.268 | 0.455 | 1.000 | 1345 | tags=35%, list=7%, signal=38% | |
| 241 | INOH_XENOPUS AXIS FORMATION WNT SIGNALING PATHWAY | 42 | -0.57 | -1.15 | 0.255 | 0.454 | 1.000 | 988 | tags=7%, list=5%, signal=8% | |
| 242 | NCI_EPHRIN B REVERSE SIGNALING | 27 | -0.61 | -1.15 | 0.261 | 0.454 | 1.000 | 2337 | tags=26%, list=13%, signal=30% | |
| 243 | BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS | 25 | -0.63 | -1.15 | 0.278 | 0.452 | 1.000 | 1500 | tags=36%, list=8%, signal=39% | |
| 244 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 17 | -0.68 | -1.15 | 0.306 | 0.452 | 1.000 | 2130 | tags=35%, list=11%, signal=40% | |
| 245 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__ | 44 | -0.56 | -1.14 | 0.223 | 0.452 | 1.000 | 2847 | tags=11%, list=15%, signal=13% | |
| 246 | BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION | 16 | -0.70 | -1.14 | 0.303 | 0.452 | 1.000 | 1695 | tags=25%, list=9%, signal=27% | |
| 247 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP) | 179 | -0.46 | -1.14 | 0.147 | 0.452 | 1.000 | 2394 | tags=8%, list=13%, signal=10% | |
| 248 | BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION | 48 | -0.57 | -1.14 | 0.261 | 0.451 | 1.000 | 1303 | tags=27%, list=7%, signal=29% | |
| 249 | NCI_CERAMIDE SIGNALING PATHWAY | 41 | -0.56 | -1.14 | 0.242 | 0.463 | 1.000 | 2054 | tags=34%, list=11%, signal=38% | |
| 250 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | 12 | -0.72 | -1.14 | 0.340 | 0.462 | 1.000 | 2433 | tags=50%, list=13%, signal=57% | |
| 251 | NCI_GLYPICAN 3 NETWORK | 57 | -0.53 | -1.13 | 0.235 | 0.462 | 1.000 | 1415 | tags=18%, list=8%, signal=19% | |
| 252 | INOH_ERK CASCADE | 12 | -0.71 | -1.13 | 0.340 | 0.465 | 1.000 | 2620 | tags=42%, list=14%, signal=48% | |
| 253 | REACTOME_METABOLISM_OF_BILE_ACIDS_AND_BILE_SALTS | 14 | -0.69 | -1.13 | 0.343 | 0.464 | 1.000 | 1579 | tags=7%, list=8%, signal=8% | |
| 254 | NCI_SIGNALING EVENTS MEDIATED BY PRL | 21 | -0.65 | -1.13 | 0.304 | 0.468 | 1.000 | 1345 | tags=29%, list=7%, signal=31% | |
| 255 | BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR | 36 | -0.56 | -1.13 | 0.274 | 0.468 | 1.000 | 1445 | tags=17%, list=8%, signal=18% | |
| 256 | INOH_CANONICAL WNT SIGNALING PATHWAY | 73 | -0.52 | -1.13 | 0.231 | 0.468 | 1.000 | 2153 | tags=14%, list=12%, signal=15% | |
| 257 | NCI_ARF1 PATHWAY | 13 | -0.68 | -1.13 | 0.348 | 0.468 | 1.000 | 2251 | tags=54%, list=12%, signal=61% | |
| 258 | INOH_GENE EXPRESSION OF SOCS BY STAT DIMER | 13 | -0.70 | -1.12 | 0.362 | 0.475 | 1.000 | 1263 | tags=31%, list=7%, signal=33% | |
| 259 | BIOCARTA_ATM SIGNALING PATHWAY | 16 | -0.67 | -1.12 | 0.337 | 0.479 | 1.000 | 1160 | tags=31%, list=6%, signal=33% | |
| 260 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS | 10 | -0.73 | -1.11 | 0.377 | 0.486 | 1.000 | 1579 | tags=10%, list=8%, signal=11% | |
| 261 | NCI_NECTIN ADHESION PATHWAY | 94 | -0.49 | -1.11 | 0.239 | 0.495 | 1.000 | 2381 | tags=28%, list=13%, signal=32% | |
| 262 | REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_ | 93 | -0.48 | -1.10 | 0.229 | 0.506 | 1.000 | 1492 | tags=4%, list=8%, signal=5% | |
| 263 | REACTOME_SPHINGOLIPID_METABOLISM | 10 | -0.70 | -1.10 | 0.403 | 0.508 | 1.000 | 2238 | tags=40%, list=12%, signal=45% | |
| 264 | INOH_BMP2 SIGNALING PATHWAY(THROUGH SMAD) | 10 | -0.73 | -1.10 | 0.380 | 0.509 | 1.000 | 988 | tags=20%, list=5%, signal=21% | |
| 265 | NCI_INTEGRINS IN ANGIOGENESIS | 63 | -0.51 | -1.10 | 0.272 | 0.511 | 1.000 | 2076 | tags=29%, list=11%, signal=32% | |
| 266 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 12 | -0.69 | -1.10 | 0.391 | 0.509 | 1.000 | 923 | tags=8%, list=5%, signal=9% | |
| 267 | BIOCARTA_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION | 12 | -0.68 | -1.10 | 0.386 | 0.510 | 1.000 | 863 | tags=25%, list=5%, signal=26% | |
| 268 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 13 | -0.68 | -1.09 | 0.386 | 0.513 | 1.000 | 3233 | tags=15%, list=17%, signal=19% | |
| 269 | BIOCARTA_REGULATION OF BAD PHOSPHORYLATION | 20 | -0.62 | -1.09 | 0.350 | 0.512 | 1.000 | 1445 | tags=25%, list=8%, signal=27% | |
| 270 | BIOCARTA_PLATELET AMYLOID PRECURSOR PROTEIN PATHWAY | 13 | -0.68 | -1.09 | 0.390 | 0.514 | 1.000 | 2595 | tags=15%, list=14%, signal=18% | |
| 271 | REACTOME_DEATH_RECEPTOR__SIGNALLING | 11 | -0.68 | -1.09 | 0.399 | 0.515 | 1.000 | 3209 | tags=45%, list=17%, signal=55% | |
| 272 | REACTOME_IRS_RELATED_EVENTS | 21 | -0.60 | -1.09 | 0.333 | 0.521 | 1.000 | 2153 | tags=29%, list=12%, signal=32% | |
| 273 | NCI_PDGFR-ALPHA SIGNALING PATHWAY | 20 | -0.61 | -1.08 | 0.340 | 0.524 | 1.000 | 3423 | tags=35%, list=18%, signal=43% | |
| 274 | INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 16 | -0.64 | -1.08 | 0.378 | 0.522 | 1.000 | 1964 | tags=31%, list=11%, signal=35% | |
| 275 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE) | 20 | -0.61 | -1.08 | 0.369 | 0.521 | 1.000 | 2192 | tags=45%, list=12%, signal=51% | |
| 276 | INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 17 | -0.63 | -1.08 | 0.372 | 0.521 | 1.000 | 1964 | tags=29%, list=11%, signal=33% | |
| 277 | NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING | 40 | -0.53 | -1.07 | 0.344 | 0.546 | 1.000 | 1452 | tags=23%, list=8%, signal=24% | |
| 278 | INOH_WNT SECRETORY PATHWAY (CANONICAL) | 47 | -0.51 | -1.07 | 0.333 | 0.546 | 1.000 | 1447 | tags=9%, list=8%, signal=9% | |
| 279 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | 12 | -0.66 | -1.06 | 0.411 | 0.549 | 1.000 | 1579 | tags=25%, list=8%, signal=27% | |
| 280 | REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE | 22 | -0.60 | -1.06 | 0.366 | 0.548 | 1.000 | 1695 | tags=23%, list=9%, signal=25% | |
| 281 | INOH_WNT SECRETORY PATHWAY (MAMMAL) | 48 | -0.51 | -1.06 | 0.325 | 0.547 | 1.000 | 1447 | tags=8%, list=8%, signal=9% | |
| 282 | BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA | 33 | -0.55 | -1.06 | 0.347 | 0.545 | 1.000 | 1222 | tags=27%, list=7%, signal=29% | |
| 283 | NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2 | 62 | -0.49 | -1.06 | 0.323 | 0.548 | 1.000 | 2188 | tags=27%, list=12%, signal=31% | |
| 284 | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | 22 | -0.60 | -1.06 | 0.371 | 0.548 | 1.000 | 1695 | tags=23%, list=9%, signal=25% | |
| 285 | BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES | 29 | -0.56 | -1.06 | 0.370 | 0.547 | 1.000 | 2130 | tags=31%, list=11%, signal=35% | |
| 286 | INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING) | 16 | -0.64 | -1.06 | 0.420 | 0.546 | 1.000 | 1964 | tags=31%, list=11%, signal=35% | |
| 287 | REACTOME_IRS_MEDIATED_SIGNALLING | 20 | -0.60 | -1.05 | 0.400 | 0.559 | 1.000 | 2153 | tags=30%, list=12%, signal=34% | |
| 288 | REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | 10 | -0.69 | -1.05 | 0.461 | 0.559 | 1.000 | 1034 | tags=10%, list=6%, signal=11% | |
| 289 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | 11 | -0.68 | -1.05 | 0.455 | 0.563 | 1.000 | 3209 | tags=45%, list=17%, signal=55% | |
| 290 | BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF) | 15 | -0.63 | -1.05 | 0.428 | 0.562 | 1.000 | 1695 | tags=27%, list=9%, signal=29% | |
| 291 | INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING) | 16 | -0.64 | -1.05 | 0.449 | 0.562 | 1.000 | 1964 | tags=31%, list=11%, signal=35% | |
| 292 | NCI_IGF1 PATHWAY | 124 | -0.44 | -1.04 | 0.326 | 0.568 | 1.000 | 2534 | tags=30%, list=14%, signal=34% | |
| 293 | INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING | 193 | -0.42 | -1.04 | 0.327 | 0.569 | 1.000 | 2411 | tags=24%, list=13%, signal=27% | |
| 294 | NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS | 13 | -0.65 | -1.04 | 0.448 | 0.571 | 1.000 | 4217 | tags=38%, list=23%, signal=50% | |
| 295 | REACTOME_CD28_CO_STIMULATION | 12 | -0.65 | -1.04 | 0.463 | 0.569 | 1.000 | 693 | tags=17%, list=4%, signal=17% | |
| 296 | INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 10 | -0.67 | -1.04 | 0.474 | 0.568 | 1.000 | 1403 | tags=30%, list=8%, signal=32% | |
| 297 | NCI_CANONICAL WNT SIGNALING PATHWAY | 49 | -0.50 | -1.04 | 0.395 | 0.573 | 1.000 | 1415 | tags=16%, list=8%, signal=18% | |
| 298 | BIOCARTA_TGF BETA SIGNALING PATHWAY | 19 | -0.60 | -1.03 | 0.450 | 0.575 | 1.000 | 1222 | tags=21%, list=7%, signal=23% | |
| 299 | NETPATH_IL6 | 57 | -0.48 | -1.03 | 0.359 | 0.575 | 1.000 | 2146 | tags=42%, list=12%, signal=47% | |
| 300 | BIOCARTA_IGF-1 SIGNALING PATHWAY | 19 | -0.58 | -1.03 | 0.430 | 0.577 | 1.000 | 1842 | tags=26%, list=10%, signal=29% | |
| 301 | BIOCARTA_OXIDATIVE STRESS INDUCED GENE EXPRESSION VIA NRF2 | 16 | -0.61 | -1.03 | 0.414 | 0.576 | 1.000 | 1863 | tags=25%, list=10%, signal=28% | |
| 302 | BIOCARTA_TELOMERES TELOMERASE CELLULAR AGING AND IMMORTALITY | 15 | -0.62 | -1.03 | 0.454 | 0.575 | 1.000 | 1500 | tags=27%, list=8%, signal=29% | |
| 303 | NCI_WNT SIGNALING | 49 | -0.50 | -1.03 | 0.409 | 0.575 | 1.000 | 1415 | tags=16%, list=8%, signal=18% | |
| 304 | NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA | 46 | -0.50 | -1.03 | 0.389 | 0.573 | 1.000 | 2477 | tags=30%, list=13%, signal=35% | |
| 305 | BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION | 19 | -0.59 | -1.02 | 0.449 | 0.589 | 1.000 | 1445 | tags=26%, list=8%, signal=29% | |
| 306 | NETPATH_IFN-GAMMA | 67 | -0.47 | -1.01 | 0.382 | 0.599 | 1.000 | 2248 | tags=36%, list=12%, signal=41% | |
| 307 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (P38 CASCADE) | 24 | -0.56 | -1.01 | 0.433 | 0.598 | 1.000 | 2192 | tags=33%, list=12%, signal=38% | |
| 308 | BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS | 16 | -0.61 | -1.01 | 0.468 | 0.605 | 1.000 | 2314 | tags=38%, list=12%, signal=43% | |
| 309 | NCI_ANDROGEN-MEDIATED SIGNALING | 101 | -0.44 | -1.01 | 0.408 | 0.606 | 1.000 | 2026 | tags=25%, list=11%, signal=28% | |
| 310 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I | 10 | -0.66 | -1.01 | 0.498 | 0.607 | 1.000 | 2708 | tags=30%, list=15%, signal=35% | |
| 311 | CELLMAP_WNT | 65 | -0.47 | -1.01 | 0.440 | 0.606 | 1.000 | 2146 | tags=20%, list=12%, signal=23% | |
| 312 | INOH_P38 CASCADE | 12 | -0.63 | -1.01 | 0.495 | 0.605 | 1.000 | 2042 | tags=42%, list=11%, signal=47% | |
| 313 | NCI_LPA4-MEDIATED SIGNALING EVENTS | 12 | -0.63 | -1.01 | 0.486 | 0.603 | 1.000 | 2394 | tags=17%, list=13%, signal=19% | |
| 314 | INOH_IL-1 SIGNALING PATHWAY (THROUGH P38 CASCADE) | 24 | -0.55 | -1.00 | 0.460 | 0.609 | 1.000 | 2042 | tags=29%, list=11%, signal=33% | |
| 315 | BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS | 19 | -0.56 | -0.99 | 0.475 | 0.626 | 1.000 | 1842 | tags=26%, list=10%, signal=29% | |
| 316 | BIOCARTA_IL 6 SIGNALING PATHWAY | 13 | -0.62 | -0.99 | 0.505 | 0.624 | 1.000 | 2673 | tags=38%, list=14%, signal=45% | |
| 317 | NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION | 14 | -0.60 | -0.99 | 0.480 | 0.627 | 1.000 | 1839 | tags=21%, list=10%, signal=24% | |
| 318 | BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA | 28 | -0.53 | -0.99 | 0.460 | 0.631 | 1.000 | 1933 | tags=25%, list=10%, signal=28% | |
| 319 | NCI_ALPHA-SYNUCLEIN SIGNALING | 32 | -0.51 | -0.98 | 0.479 | 0.650 | 1.000 | 1552 | tags=22%, list=8%, signal=24% | |
| 320 | NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY | 80 | -0.44 | -0.97 | 0.500 | 0.653 | 1.000 | 1939 | tags=25%, list=10%, signal=28% | |
| 321 | CELLMAP_ANDROGENRECEPTOR | 70 | -0.44 | -0.97 | 0.498 | 0.659 | 1.000 | 1939 | tags=29%, list=10%, signal=32% | |
| 322 | BIOCARTA_THE INFORMATION PROCESSING PATHWAY AT THE IFN BETA ENHANCER | 26 | -0.52 | -0.97 | 0.518 | 0.657 | 1.000 | 1160 | tags=31%, list=6%, signal=33% | |
| 323 | BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION | 28 | -0.52 | -0.97 | 0.518 | 0.659 | 1.000 | 1222 | tags=25%, list=7%, signal=27% | |
| 324 | BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM | 14 | -0.58 | -0.97 | 0.541 | 0.658 | 1.000 | 2275 | tags=36%, list=12%, signal=41% | |
| 325 | BIOCARTA_REGULATION OF PGC-1A | 18 | -0.57 | -0.97 | 0.515 | 0.660 | 1.000 | 1883 | tags=33%, list=10%, signal=37% | |
| 326 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | 16 | -0.57 | -0.96 | 0.525 | 0.659 | 1.000 | 2046 | tags=13%, list=11%, signal=14% | |
| 327 | NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK | 33 | -0.50 | -0.96 | 0.485 | 0.660 | 1.000 | 1880 | tags=18%, list=10%, signal=20% | |
| 328 | BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS | 10 | -0.62 | -0.96 | 0.555 | 0.660 | 1.000 | 1500 | tags=10%, list=8%, signal=11% | |
| 329 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II | 31 | -0.50 | -0.96 | 0.494 | 0.661 | 1.000 | 1335 | tags=16%, list=7%, signal=17% | |
| 330 | INOH_B-RAF ACTIVATION SIGNALING | 26 | -0.52 | -0.96 | 0.518 | 0.665 | 1.000 | 2350 | tags=31%, list=13%, signal=35% | |
| 331 | CELLMAP_TGFBR | 107 | -0.40 | -0.94 | 0.563 | 0.698 | 1.000 | 1954 | tags=24%, list=10%, signal=27% | |
| 332 | BIOCARTA_IL-10 ANTI-INFLAMMATORY SIGNALING PATHWAY | 13 | -0.59 | -0.94 | 0.584 | 0.699 | 1.000 | 2017 | tags=38%, list=11%, signal=43% | |
| 333 | CELLMAP_NOTCH | 45 | -0.46 | -0.94 | 0.559 | 0.705 | 1.000 | 1797 | tags=24%, list=10%, signal=27% | |
| 334 | BIOCARTA_ROLE OF RAN IN MITOTIC SPINDLE REGULATION | 11 | -0.60 | -0.93 | 0.607 | 0.709 | 1.000 | 7 | tags=9%, list=0%, signal=9% | |
| 335 | BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY | 16 | -0.54 | -0.93 | 0.567 | 0.707 | 1.000 | 1138 | tags=25%, list=6%, signal=27% | |
| 336 | BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB | 12 | -0.59 | -0.93 | 0.590 | 0.709 | 1.000 | 1160 | tags=33%, list=6%, signal=36% | |
| 337 | NETPATH_NGF | 45 | -0.46 | -0.93 | 0.601 | 0.708 | 1.000 | 1842 | tags=27%, list=10%, signal=30% | |
| 338 | NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT | 86 | -0.41 | -0.93 | 0.630 | 0.714 | 1.000 | 1695 | tags=24%, list=9%, signal=27% | |
| 339 | REACTOME_MUSCLE_CONTRACTION | 25 | -0.50 | -0.92 | 0.552 | 0.715 | 1.000 | 2621 | tags=16%, list=14%, signal=19% | |
| 340 | BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES | 38 | -0.47 | -0.92 | 0.609 | 0.721 | 1.000 | 1298 | tags=21%, list=7%, signal=23% | |
| 341 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 12 | -0.57 | -0.92 | 0.593 | 0.720 | 1.000 | 2621 | tags=17%, list=14%, signal=19% | |
| 342 | NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS | 47 | -0.45 | -0.92 | 0.594 | 0.718 | 1.000 | 1552 | tags=17%, list=8%, signal=19% | |
| 343 | REACTOME_MEMBRANE_TRAFFICKING | 26 | -0.50 | -0.92 | 0.599 | 0.721 | 1.000 | 2640 | tags=38%, list=14%, signal=45% | |
| 344 | NCI_VEGFR1 SPECIFIC SIGNALS | 27 | -0.49 | -0.92 | 0.629 | 0.723 | 1.000 | 1842 | tags=26%, list=10%, signal=29% | |
| 345 | REACTOME_PI3K_AKT_SIGNALLING | 12 | -0.58 | -0.91 | 0.612 | 0.722 | 1.000 | 601 | tags=17%, list=3%, signal=17% | |
| 346 | NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY | 59 | -0.42 | -0.91 | 0.623 | 0.730 | 1.000 | 1750 | tags=17%, list=9%, signal=19% | |
| 347 | BIOCARTA_TNF/STRESS RELATED SIGNALING | 22 | -0.51 | -0.91 | 0.568 | 0.729 | 1.000 | 2828 | tags=45%, list=15%, signal=54% | |
| 348 | BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY | 27 | -0.48 | -0.91 | 0.603 | 0.727 | 1.000 | 2026 | tags=30%, list=11%, signal=33% | |
| 349 | BIOCARTA_B CELL SURVIVAL PATHWAY | 12 | -0.56 | -0.90 | 0.613 | 0.749 | 1.000 | 781 | tags=17%, list=4%, signal=17% | |
| 350 | BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM | 16 | -0.53 | -0.89 | 0.614 | 0.752 | 1.000 | 701 | tags=25%, list=4%, signal=26% | |
| 351 | BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS | 19 | -0.52 | -0.89 | 0.625 | 0.750 | 1.000 | 1500 | tags=21%, list=8%, signal=23% | |
| 352 | HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS | 11 | -0.58 | -0.89 | 0.674 | 0.749 | 1.000 | 2708 | tags=27%, list=15%, signal=32% | |
| 353 | BIOCARTA_P53 SIGNALING PATHWAY | 13 | -0.55 | -0.89 | 0.618 | 0.750 | 1.000 | 1138 | tags=31%, list=6%, signal=33% | |
| 354 | INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING | 105 | -0.38 | -0.89 | 0.775 | 0.761 | 1.000 | 2394 | tags=18%, list=13%, signal=21% | |
| 355 | NCI_NONGENOTROPIC ANDROGEN SIGNALING | 24 | -0.48 | -0.88 | 0.637 | 0.772 | 1.000 | 2026 | tags=21%, list=11%, signal=23% | |
| 356 | BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION | 26 | -0.47 | -0.88 | 0.632 | 0.777 | 1.000 | 1335 | tags=12%, list=7%, signal=12% | |
| 357 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | 20 | -0.50 | -0.87 | 0.632 | 0.776 | 1.000 | 1695 | tags=25%, list=9%, signal=27% | |
| 358 | BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS | 25 | -0.47 | -0.87 | 0.626 | 0.775 | 1.000 | 2337 | tags=24%, list=13%, signal=27% | |
| 359 | NETPATH_IL1 | 27 | -0.47 | -0.87 | 0.666 | 0.773 | 1.000 | 1927 | tags=33%, list=10%, signal=37% | |
| 360 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC) | 22 | -0.49 | -0.87 | 0.655 | 0.772 | 1.000 | 2350 | tags=32%, list=13%, signal=36% | |
| 361 | BIOCARTA_ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE PKA | 25 | -0.48 | -0.87 | 0.626 | 0.770 | 1.000 | 1445 | tags=16%, list=8%, signal=17% | |
| 362 | BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION | 16 | -0.52 | -0.87 | 0.626 | 0.769 | 1.000 | 2042 | tags=44%, list=11%, signal=49% | |
| 363 | CELLMAP_HEDGEHOG | 14 | -0.52 | -0.87 | 0.646 | 0.777 | 1.000 | 1773 | tags=14%, list=10%, signal=16% | |
| 364 | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS | 44 | -0.42 | -0.87 | 0.673 | 0.781 | 1.000 | 1750 | tags=18%, list=9%, signal=20% | |
| 365 | NETPATH_FLK2_FLT3 | 16 | -0.51 | -0.86 | 0.659 | 0.793 | 1.000 | 1248 | tags=38%, list=7%, signal=40% | |
| 366 | REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION | 19 | -0.49 | -0.85 | 0.669 | 0.799 | 1.000 | 1222 | tags=16%, list=7%, signal=17% | |
| 367 | BIOCARTA_ALK IN CARDIAC MYOCYTES | 27 | -0.46 | -0.85 | 0.679 | 0.799 | 1.000 | 1144 | tags=15%, list=6%, signal=16% | |
| 368 | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 | 22 | -0.48 | -0.85 | 0.685 | 0.798 | 1.000 | 1243 | tags=18%, list=7%, signal=19% | |
| 369 | REACTOME_TIE2_SIGNALING | 12 | -0.53 | -0.85 | 0.706 | 0.804 | 1.000 | 365 | tags=8%, list=2%, signal=8% | |
| 370 | NCI_EPHRINA-EPHA PATHWAY | 40 | -0.41 | -0.84 | 0.735 | 0.818 | 1.000 | 2337 | tags=23%, list=13%, signal=26% | |
| 371 | BIOCARTA_ADP-RIBOSYLATION FACTOR | 18 | -0.49 | -0.83 | 0.718 | 0.825 | 1.000 | 2330 | tags=44%, list=13%, signal=51% | |
| 372 | BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION | 10 | -0.54 | -0.83 | 0.713 | 0.829 | 1.000 | 4098 | tags=30%, list=22%, signal=38% | |
| 373 | REACTOME_FORMATION_OF_FIBRIN_CLOT__CLOTTING_CASCADE_ | 28 | -0.44 | -0.83 | 0.742 | 0.827 | 1.000 | 1208 | tags=11%, list=6%, signal=11% | |
| 374 | NCI_FOXA TRANSCRIPTION FACTOR NETWORKS | 65 | -0.38 | -0.82 | 0.865 | 0.837 | 1.000 | 2128 | tags=12%, list=11%, signal=14% | |
| 375 | NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY | 43 | -0.40 | -0.82 | 0.745 | 0.835 | 1.000 | 2282 | tags=26%, list=12%, signal=29% | |
| 376 | BIOCARTA_MECHANISM OF PROTEIN IMPORT INTO THE NUCLEUS | 11 | -0.53 | -0.82 | 0.739 | 0.842 | 1.000 | 863 | tags=18%, list=5%, signal=19% | |
| 377 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | 12 | -0.52 | -0.82 | 0.733 | 0.842 | 1.000 | 1923 | tags=33%, list=10%, signal=37% | |
| 378 | BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION | 44 | -0.39 | -0.81 | 0.817 | 0.845 | 1.000 | 2354 | tags=16%, list=13%, signal=18% | |
| 379 | NCI_ARF6 DOWNSTREAM PATHWAY | 25 | -0.44 | -0.81 | 0.733 | 0.844 | 1.000 | 2251 | tags=48%, list=12%, signal=55% | |
| 380 | BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1 | 12 | -0.51 | -0.81 | 0.749 | 0.851 | 1.000 | 1748 | tags=33%, list=9%, signal=37% | |
| 381 | BIOCARTA_IL 4 SIGNALING PATHWAY | 11 | -0.51 | -0.79 | 0.748 | 0.879 | 1.000 | 2938 | tags=45%, list=16%, signal=54% | |
| 382 | BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE | 14 | -0.48 | -0.79 | 0.746 | 0.879 | 1.000 | 1303 | tags=21%, list=7%, signal=23% | |
| 383 | NCI_HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK | 57 | -0.37 | -0.79 | 0.888 | 0.884 | 1.000 | 1553 | tags=18%, list=8%, signal=19% | |
| 384 | BIOCARTA_STATHMIN AND BREAST CANCER RESISTANCE TO ANTIMICROTUBULE AGENTS | 19 | -0.45 | -0.78 | 0.799 | 0.883 | 1.000 | 2107 | tags=21%, list=11%, signal=24% | |
| 385 | INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I) | 13 | -0.49 | -0.78 | 0.768 | 0.886 | 1.000 | 1144 | tags=15%, list=6%, signal=16% | |
| 386 | BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES | 23 | -0.43 | -0.78 | 0.827 | 0.889 | 1.000 | 1883 | tags=35%, list=10%, signal=39% | |
| 387 | INOH_INTEGRIN SIGNALING PATHWAY | 92 | -0.34 | -0.78 | 0.974 | 0.889 | 1.000 | 2350 | tags=15%, list=13%, signal=17% | |
| 388 | HUMANCYC_TCA CYCLE | 16 | -0.45 | -0.76 | 0.789 | 0.904 | 1.000 | 987 | tags=19%, list=5%, signal=20% | |
| 389 | INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4 | 13 | -0.49 | -0.76 | 0.809 | 0.903 | 1.000 | 1144 | tags=15%, list=6%, signal=16% | |
| 390 | REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS | 13 | -0.48 | -0.76 | 0.785 | 0.902 | 1.000 | 3139 | tags=46%, list=17%, signal=55% | |
| 391 | HUMANCYC_SUPERPATHWAY OF GLYOXYLATE BYPASS AND TCA | 16 | -0.45 | -0.76 | 0.794 | 0.903 | 1.000 | 987 | tags=19%, list=5%, signal=20% | |
| 392 | REACTOME_REGULATORY_RNA_PATHWAYS | 10 | -0.49 | -0.75 | 0.792 | 0.918 | 1.000 | 7 | tags=10%, list=0%, signal=10% | |
| 393 | BIOCARTA_INTEGRIN SIGNALING PATHWAY | 30 | -0.39 | -0.74 | 0.886 | 0.922 | 1.000 | 1933 | tags=27%, list=10%, signal=30% | |
| 394 | NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA | 34 | -0.38 | -0.74 | 0.902 | 0.921 | 1.000 | 2639 | tags=29%, list=14%, signal=34% | |
| 395 | BIOCARTA_REGULATION OF CELL CYCLE PROGRESSION BY PLK3 | 17 | -0.43 | -0.74 | 0.856 | 0.925 | 1.000 | 1232 | tags=12%, list=7%, signal=13% | |
| 396 | REACTOME_STRIATED_MUSCLE_CONTRACTION | 14 | -0.44 | -0.73 | 0.829 | 0.935 | 1.000 | 2349 | tags=14%, list=13%, signal=16% | |
| 397 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | 18 | -0.42 | -0.71 | 0.884 | 0.948 | 1.000 | 1014 | tags=11%, list=5%, signal=12% | |
| 398 | REACTOME_GLUCONEOGENESIS | 11 | -0.45 | -0.71 | 0.845 | 0.949 | 1.000 | 32 | tags=9%, list=0%, signal=9% | |
| 399 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | 25 | -0.38 | -0.70 | 0.930 | 0.958 | 1.000 | 2428 | tags=20%, list=13%, signal=23% | |
| 400 | NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES | 21 | -0.39 | -0.69 | 0.957 | 0.968 | 1.000 | 2477 | tags=29%, list=13%, signal=33% | |
| 401 | BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY | 16 | -0.40 | -0.68 | 0.906 | 0.967 | 1.000 | 1883 | tags=31%, list=10%, signal=35% | |
| 402 | BIOCARTA_FIBRINOLYSIS PATHWAY | 12 | -0.43 | -0.68 | 0.880 | 0.966 | 1.000 | 701 | tags=8%, list=4%, signal=9% | |
| 403 | INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 18 | -0.40 | -0.68 | 0.930 | 0.967 | 1.000 | 1392 | tags=22%, list=7%, signal=24% | |
| 404 | INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5) | 10 | -0.44 | -0.68 | 0.883 | 0.966 | 1.000 | 5947 | tags=50%, list=32%, signal=73% | |
| 405 | NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1 | 17 | -0.40 | -0.68 | 0.926 | 0.963 | 1.000 | 2026 | tags=29%, list=11%, signal=33% | |
| 406 | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_ALPHA__PPARALPHA_ | 11 | -0.44 | -0.68 | 0.869 | 0.961 | 1.000 | 2289 | tags=18%, list=12%, signal=21% | |
| 407 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | 17 | -0.39 | -0.66 | 0.943 | 0.969 | 1.000 | 974 | tags=18%, list=5%, signal=19% | |
| 408 | BIOCARTA_THE IGF-1 RECEPTOR AND LONGEVITY | 16 | -0.39 | -0.66 | 0.934 | 0.970 | 1.000 | 1248 | tags=13%, list=7%, signal=13% | |
| 409 | BIOCARTA_TNFR1 SIGNALING PATHWAY | 16 | -0.36 | -0.62 | 0.958 | 0.985 | 1.000 | 2639 | tags=31%, list=14%, signal=36% | |
| 410 | REACTOME_EXOCYTOSIS_OF_ALPHA_GRANULE_ | 40 | -0.30 | -0.59 | 0.998 | 0.990 | 1.000 | 3248 | tags=10%, list=17%, signal=12% | |
| 411 | BIOCARTA_STRESS INDUCTION OF HSP REGULATION | 14 | -0.36 | -0.57 | 0.983 | 0.992 | 1.000 | 357 | tags=7%, list=2%, signal=7% | |
| 412 | NCI_VISUAL SIGNAL TRANSDUCTION: RODS | 19 | -0.23 | -0.40 | 1.000 | 0.999 | 1.000 | 3091 | tags=11%, list=17%, signal=13% |