Details for gene set SHEPARD_CRASH_AND_BURN_MUT_VS_WT

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_wtNotch_versus_truncNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	SHEPARD_CRASH_AND_BURN_MUT_VS_WT_UP
Enrichment Score (ES)	-0.6369492
Normalized Enrichment Score (NES)	-1.5699059
Nominal p-value	0.0016051364
FDR q-value	0.25785804
FWER p-Value	0.996

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ETF1	6770075	307	0.780	0.0076	No
2	POP4	4560600	1015	0.388	-0.0185	No
3	FTSJ3	3140100	1016	0.388	-0.0065	No
4	PINX1	3360154	1055	0.372	0.0030	No
5	MRPL22	6400520	1105	0.357	0.0115	No
6	VRK2	3800692 6940056	1119	0.354	0.0218	No
7	TOB1	4150138	1181	0.340	0.0291	No
8	CYP51A1	4590427	1233	0.327	0.0365	No
9	PFKFB3	630706	1234	0.327	0.0466	No
10	MKNK2	1240020 5270092	1413	0.275	0.0456	No
11	NOL6	2810504 3120050 3840021 6860315	1657	0.224	0.0394	No
12	CASP8	4850154	1665	0.223	0.0460	No
13	CIRH1A	2340372	1813	0.196	0.0441	No
14	PPAN	540398	2179	0.141	0.0288	No
15	STARD10	1400619 4570170	2221	0.135	0.0308	No
16	PES1	2470427	2279	0.129	0.0317	No
17	CCNG2	3190095	2287	0.128	0.0353	No
18	AK3L1	7100601	2356	0.120	0.0354	No
19	DNAJA3	1980671 6220338	2454	0.111	0.0335	No
20	SLC16A6	1690156	2524	0.104	0.0330	No
21	FN1	1170601 2970647 6220288 6940037	2696	0.090	0.0266	No
22	SLC3A2	5270358	2740	0.086	0.0269	No
23	NOLA1	730093	2910	0.074	0.0201	No
24	CORT	360008 2340092	3036	0.066	0.0154	No
25	MDM2	3450053 5080138	3045	0.065	0.0170	No
26	RPS27L	50577	3102	0.061	0.0158	No
27	NOL7	6520332	3231	0.053	0.0106	No
28	SRPRB	1500138 5130156 5910064	3474	0.043	-0.0012	No
29	AP3M1	5340433	3573	0.039	-0.0053	No
30	ARMET	5130670	3648	0.036	-0.0081	No
31	CCNG1	870402 1500685 6110594	4162	0.023	-0.0352	No
32	SEC23B	3390632 3840497	4192	0.023	-0.0360	No
33	SLC12A3	1980592 2350056	4629	0.016	-0.0591	No
34	ANKRD22	4480746	5315	0.010	-0.0958	No
35	ING5	3830440 5910239 6200471 6650576	5497	0.009	-0.1053	No
36	PTGS2	2510301 3170369	5586	0.009	-0.1098	No
37	AP1M2	2900138 6040324 6370537	5819	0.007	-0.1221	No
38	NOG	2320609	5847	0.007	-0.1234	No
39	RERG	5910324	5880	0.007	-0.1249	No
40	ANGPTL3	6180497	6083	0.006	-0.1356	No
41	SSR1	5890100	6593	0.004	-0.1630	No
42	BXDC1	2640068	7064	0.002	-0.1883	No
43	FST	1110600	7185	0.002	-0.1948	No
44	CYP27B1	5270114 5360010	7596	0.001	-0.2169	No
45	BTG2	2350411	7706	0.001	-0.2228	No
46	ADAM10	3780156	8393	-0.001	-0.2598	No
47	RBP4	4540131	8528	-0.002	-0.2670	No
48	PHLDA2	4810494	8570	-0.002	-0.2692	No
49	CTH	1190332 5290139	8861	-0.003	-0.2848	No
50	IGFBP1	5720435	9025	-0.003	-0.2935	No
51	CYP24A1	2340338	9065	-0.003	-0.2955	No
52	IBRDC2	5130041	10160	-0.007	-0.3544	No
53	BMP2	6620687	10310	-0.007	-0.3623	No
54	RRS1	4560551	10321	-0.007	-0.3626	No
55	B3GNT1	2350446	10453	-0.008	-0.3694	No
56	ODC1	5670168	10563	-0.008	-0.3750	No
57	WDR12	4560722	10818	-0.009	-0.3885	No
58	BOP1	4810040	11149	-0.011	-0.4060	No
59	ITGB1BP3	60441 730750	11394	-0.012	-0.4188	No
60	HSPA1L	4010538	11468	-0.012	-0.4224	No
61	CDX4	6380164	11493	-0.012	-0.4233	No
62	CYP26A1	380022 2690600	12057	-0.016	-0.4532	No
63	ATF3	1940546	12131	-0.017	-0.4567	No
64	FBL	5130020	12165	-0.017	-0.4579	No
65	SIX2	1450551	12315	-0.018	-0.4654	No
66	JUN	840170	12454	-0.019	-0.4723	No
67	MRPL52	1170204	12847	-0.023	-0.4927	No
68	PPP1R14A	870114 4760187	12875	-0.024	-0.4935	No
69	PDLIM3	1410095	12906	-0.024	-0.4943	No
70	C6	1770154 2900129	12927	-0.024	-0.4947	No
71	ABCF2	630040 3140035 6450601	13010	-0.025	-0.4983	No
72	DDX51	5550044 6350270 6590750	13196	-0.027	-0.5075	No
73	PTGES2	4210097	13497	-0.032	-0.5227	No
74	MYOG	3190672	13605	-0.034	-0.5275	No
75	SNAI1	6590253	13687	-0.035	-0.5307	No
76	TOMM20	6510113	14187	-0.045	-0.5563	No
77	FOS	1850315	14838	-0.065	-0.5894	No
78	JDP2	2360500	14937	-0.069	-0.5926	No
79	EIF4E	1580403 70133 6380215	14939	-0.069	-0.5905	No
80	TP53	6130707	15076	-0.075	-0.5955	No
81	TAF9	1850458 3830136	15180	-0.080	-0.5986	No
82	MMP9	580338	15215	-0.082	-0.5979	No
83	JUNB	4230048	15318	-0.088	-0.6007	No
84	WDR8	520377 6200093	15342	-0.089	-0.5991	No
85	HSPA4	1050170 3450309	15472	-0.098	-0.6030	No
86	CYR61	1240408 5290026 4120452 6550008	15657	-0.109	-0.6096	No
87	ATPIF1	7050577	15777	-0.119	-0.6123	No
88	SLC12A7	6860079	15862	-0.127	-0.6129	No
89	GADD45B	2350408	15876	-0.128	-0.6096	No
90	PIM1	630047	16020	-0.143	-0.6129	No
91	CIC	6370161	16078	-0.149	-0.6114	No
92	MRPS26	4120113	16131	-0.154	-0.6094	No
93	DRG2	6770563	16316	-0.177	-0.6138	No
94	BRF1	2100047	16406	-0.189	-0.6128	No
95	MMP2	2570603	16423	-0.190	-0.6077	No
96	SERPINH1	6130014	16965	-0.267	-0.6286	Yes
97	MRPL12	3120112	16980	-0.270	-0.6210	Yes
98	ITGB4BP	1400541	16994	-0.272	-0.6132	Yes
99	MYBBP1A	110592 2570435 2900711	17022	-0.277	-0.6061	Yes
100	TUBA8	3710484	17103	-0.291	-0.6014	Yes
101	WBSCR22	3130070 4120551 5570433	17310	-0.333	-0.6021	Yes
102	MRPS18B	5570086	17340	-0.340	-0.5931	Yes
103	SHMT1	5900132	17352	-0.342	-0.5831	Yes
104	MRPS18A	6770433	17486	-0.366	-0.5789	Yes
105	SGK	1400131 2480056	17670	-0.418	-0.5758	Yes
106	GPD1	2480095	17833	-0.474	-0.5698	Yes
107	PLK3	2640592	17834	-0.475	-0.5550	Yes
108	ELOVL1	2450019 4760138 5340685	17838	-0.478	-0.5403	Yes
109	CEBPB	2970019	17856	-0.485	-0.5261	Yes
110	BAX	3830008	18003	-0.553	-0.5168	Yes
111	IMPDH1	3190735 7050546	18294	-0.853	-0.5060	Yes
112	HIST1H3B	4780092	18364	-0.956	-0.4800	Yes
113	EGR1	4610347	18402	-1.010	-0.4506	Yes
114	DUSP4	2690044 2850593	18417	-1.050	-0.4187	Yes
115	HES1	4810280	18420	-1.054	-0.3861	Yes
116	CLDN4	4920739	18465	-1.162	-0.3523	Yes
117	KLF2	6860270	18525	-1.525	-0.3081	Yes
118	DSCR1	4540048 6220039	18535	-1.573	-0.2596	Yes
119	PTP4A3	3780504 6400364	18580	-2.374	-0.1882	Yes
120	IGF2	6510020	18590	-2.564	-0.1090	Yes
121	MIDN	2260132 5220377	18606	-3.548	0.0005	Yes