Details for gene set ICHIBA

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch_repos
Phenotype	phenotype_wtNotch_versus_truncNotch.cls#wtNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	ICHIBA_GVHD
Enrichment Score (ES)	-0.61330384
Normalized Enrichment Score (NES)	-1.6441138
Nominal p-value	0.0
FDR q-value	0.17541826
FWER p-Value	0.732

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LYZS	50068 6770717	35	1.744	0.0206	No
2	PKM2	6520403 70500	53	1.576	0.0400	No
3	MCM4	2760673 5420711	78	1.324	0.0558	No
4	UCK1	2650398 3130113 5130725	89	1.253	0.0714	No
5	ATP1B3	6040128	311	0.774	0.0693	No
6	LY6A	6110605	467	0.642	0.0692	No
7	EIF1	5080100	498	0.622	0.0756	No
8	TAP2	2810347	749	0.489	0.0682	No
9	USP18	4010110	774	0.481	0.0731	No
10	ICAM1	6980138	801	0.472	0.0778	No
11	1500011J06RIK	5130056	813	0.467	0.0832	No
12	IFI47	3060673	955	0.414	0.0809	No
13	NCF4	610164	1048	0.374	0.0807	No
14	IQGAP1	6660494	1108	0.357	0.0821	No
15	PSME1	450193 4480035	1125	0.353	0.0857	No
16	EXOSC8	360427	1180	0.340	0.0872	No
17	SMOC2	1170170	1195	0.336	0.0907	No
18	FKBP5	2190048	1282	0.315	0.0901	No
19	PTPRC	130402 5290148	1289	0.312	0.0938	No
20	ELOVL6	5340746	1352	0.293	0.0942	No
21	NEK9	3440402	1402	0.280	0.0951	No
22	1700013L23RIK	3390097	1505	0.255	0.0929	No
23	NR2F6	1340239 5670239 60338 4280088	1570	0.241	0.0925	No
24	HMGCS2	770725	1647	0.226	0.0913	No
25	4921506I22RIK	1340279	1649	0.226	0.0941	No
26	PSME2	4850086	1713	0.215	0.0935	No
27	BIRC5	110408 580014 1770632	1761	0.207	0.0936	No
28	BC004022	3440142	1798	0.200	0.0942	No
29	ACSL1	2900520	1934	0.177	0.0891	No
30	POM121	70152	2009	0.167	0.0872	No
31	RPAP1	4670152 6450068	2135	0.148	0.0823	No
32	LPL	1450735 2970706	2245	0.133	0.0781	No
33	STAT1	6510204 6590553	2257	0.131	0.0792	No
34	AIM1	2810142	2338	0.122	0.0764	No
35	9830147J24RIK	2690451	2358	0.120	0.0769	No
36	PPP1R2	3710278 1400725	2402	0.116	0.0760	No
37	GLTP	3440603	2580	0.099	0.0677	No
38	CD52	5910242	2858	0.078	0.0536	No
39	LY86	2230093	2899	0.075	0.0523	No
40	SPTLC2	6840324 520017	2937	0.072	0.0513	No
41	SNX10	3800035	2939	0.072	0.0521	No
42	IL6ST	5890047	2958	0.071	0.0520	No
43	UBAP2L	4120128 6650133	3047	0.065	0.0481	No
44	AIF1	130332 5220017	3066	0.064	0.0479	No
45	STX3	1190563 2640215	3173	0.057	0.0429	No
46	LRG1	5690605	3179	0.056	0.0433	No
47	ADCY9	5690168	3197	0.055	0.0431	No
48	XDH	6840446	3248	0.053	0.0411	No
49	GLT25D1	540088	3265	0.052	0.0409	No
50	NCOA3	4540195	3411	0.045	0.0335	No
51	PAPSS2	870113	3421	0.045	0.0336	No
52	NFKBIZ	2970450	3700	0.034	0.0189	No
53	MMP12	4920070	3722	0.034	0.0182	No
54	MARVELD1	6110309	3732	0.034	0.0181	No
55	RPL22	4070070	3758	0.033	0.0172	No
56	CDC5L	3130446 3390025 6400204	3840	0.030	0.0132	No
57	PBEF1	1090278	3903	0.029	0.0102	No
58	ATP11A	1240717 5570603	4106	0.024	-0.0005	No
59	GP49A	1940390	4153	0.023	-0.0027	No
60	APBB1IP	4560441 4570706 6520739	4171	0.023	-0.0034	No
61	MCM10	4920632	4179	0.023	-0.0035	No
62	LCP2	2680066 6650707	4188	0.023	-0.0036	No
63	CHI3L3	2120332	4249	0.022	-0.0066	No
64	LY75	1990358 4590136	4252	0.022	-0.0064	No
65	CSF1R	2340110 6420408	4292	0.021	-0.0083	No
66	OAT	540632	4466	0.018	-0.0175	No
67	GBP4	6520471 1980670	4540	0.017	-0.0212	No
68	PPP1R3C	2640170	4773	0.015	-0.0337	No
69	UBD	5570632	4780	0.015	-0.0338	No
70	GDF5	510440	4903	0.013	-0.0403	No
71	FPR1	3800577	4948	0.013	-0.0425	No
72	AVPR1A	2120300	4957	0.013	-0.0428	No
73	H2-EA	3870301	5032	0.012	-0.0467	No
74	MUP4	670253 4560487	5103	0.012	-0.0504	No
75	DIO1	4570279 5290112 5420148	5243	0.011	-0.0578	No
76	MSR1	940538	5324	0.010	-0.0620	No
77	CRYAA	2030164	5443	0.009	-0.0683	No
78	SERPINA6	1850707	5448	0.009	-0.0684	No
79	SC5DL	6650390	5772	0.007	-0.0860	No
80	VNN1	3940400	5776	0.007	-0.0860	No
81	CCL2	4760019	5845	0.007	-0.0896	No
82	GAS1	2120504	5882	0.007	-0.0915	No
83	PDK3	510484	5887	0.007	-0.0917	No
84	KLF10	4850056	5990	0.006	-0.0971	No
85	CES3	5050167 3290458	6131	0.006	-0.1047	No
86	ORM1	1500563	6133	0.006	-0.1047	No
87	LIFR	3360068 3830102	6180	0.006	-0.1071	No
88	A130022J15RIK	4150494	6284	0.005	-0.1127	No
89	MUP3	4480152	6336	0.005	-0.1154	No
90	ODZ3	3060725 6450292	6390	0.005	-0.1182	No
91	PRLR	1980647 1990097	6455	0.005	-0.1216	No
92	CYP2B9	360152	6551	0.004	-0.1268	No
93	CASP6	5690239 6420551	6697	0.004	-0.1346	No
94	HSD3B3	4570113	6698	0.004	-0.1346	No
95	PIRA1	4120632	6739	0.003	-0.1367	No
96	HAO3	6100368	6789	0.003	-0.1394	No
97	FABP1	6940035	6798	0.003	-0.1397	No
98	IFIT1	5270373	6898	0.003	-0.1451	No
99	GIMAP4	5570673 6550041	6947	0.003	-0.1477	No
100	TLR6	510102 3390148	7008	0.003	-0.1509	No
101	ZIC3	380020	7085	0.002	-0.1550	No
102	IFIT3	2450278 3190113 6200113	7101	0.002	-0.1558	No
103	H2-D1	2190725	7244	0.002	-0.1636	No
104	HSD17B2	3800541	7246	0.002	-0.1636	No
105	IFI202B	4070398	7274	0.002	-0.1650	No
106	PAX3	50551	7370	0.001	-0.1702	No
107	DCLRE1A	5890427	7371	0.001	-0.1702	No
108	PSCDBP	1780408	7544	0.001	-0.1795	No
109	5830411E10RIK	2940053	7586	0.001	-0.1818	No
110	LIPC	2690497	7693	0.001	-0.1875	No
111	BTG2	2350411	7706	0.001	-0.1882	No
112	PROCR	4920687	7852	0.000	-0.1961	No
113	ACTL7B	460341	7864	0.000	-0.1967	No
114	IL1RN	2370333	7976	-0.000	-0.2028	No
115	SULT2A2	2650397	7993	-0.000	-0.2036	No
116	CAR14	1450528	8325	-0.001	-0.2217	No
117	GSTM6	3940358 5670019	8392	-0.001	-0.2252	No
118	KEG1	6940603	8491	-0.002	-0.2306	No
119	PKLR	1170400 2470114	8544	-0.002	-0.2334	No
120	TGTP	2810138	8635	-0.002	-0.2383	No
121	RPS6KC1	5220619	8660	-0.002	-0.2395	No
122	TMSB4X	6620114	8770	-0.002	-0.2455	No
123	CXCL10	2450408	8847	-0.003	-0.2496	No
124	CCL6	6660390	9230	-0.004	-0.2703	No
125	HSD3B2	70068 770037 4120114 4230170 5690333	9292	-0.004	-0.2736	No
126	GBP2	50301	9484	-0.005	-0.2840	No
127	MUP5	6770279	9628	-0.005	-0.2917	No
128	ELOVL2	5720064	9698	-0.005	-0.2954	No
129	FGL2	3170731	9700	-0.005	-0.2954	No
130	GHR	2260156	9728	-0.005	-0.2968	No
131	RELN	6510037	10071	-0.006	-0.3154	No
132	ADRB3	6900072	10146	-0.007	-0.3193	No
133	GBP1	780075	10638	-0.009	-0.3460	No
134	SLC26A1	2190142	10698	-0.009	-0.3491	No
135	CYP7B1	1190309	10699	-0.009	-0.3490	No
136	CYP4A10	3170288 6130131	10716	-0.009	-0.3497	No
137	SH3GL1	6110154	10872	-0.009	-0.3581	No
138	CD5L	4070605	11124	-0.011	-0.3716	No
139	CTLA2B	4210168	11171	-0.011	-0.3740	No
140	CYP2B13	5420672	11250	-0.011	-0.3781	No
141	MS4A4D	4850632	11421	-0.012	-0.3872	No
142	SLC1A2	2230520	11881	-0.015	-0.4121	No
143	LBP	6860019	11982	-0.016	-0.4173	No
144	SAA2	1090139	12048	-0.016	-0.4207	No
145	CYP26A1	380022 2690600	12057	-0.016	-0.4209	No
146	HCK	4230592	12141	-0.017	-0.4252	No
147	IL18R1	270546	12201	-0.017	-0.4282	No
148	SULT4A1	5270161	12320	-0.018	-0.4344	No
149	PSMB9	6980471	12339	-0.018	-0.4351	No
150	ORM3	3310128	12356	-0.018	-0.4358	No
151	ORM2	2100048	12362	-0.019	-0.4358	No
152	SERPINA10	2360114	12476	-0.020	-0.4417	No
153	BMPR2	5340066 6960328	12773	-0.022	-0.4576	No
154	SCMH1	3190019 6770450	12833	-0.023	-0.4605	No
155	PTGS1	730193 1780273 6450195	12981	-0.025	-0.4682	No
156	PLK1	1780369 2640121	13157	-0.027	-0.4774	No
157	CASP1	2360546	13332	-0.029	-0.4865	No
158	OSBPL5	3840537 6040286	13464	-0.031	-0.4932	No
159	IGFALS	6350195	13472	-0.031	-0.4932	No
160	CYP2B10	3390100	13510	-0.032	-0.4948	No
161	KRT1-18	4060563	13527	-0.032	-0.4953	No
162	NNMT	450471	13547	-0.033	-0.4959	No
163	S100A11	2260064	13571	-0.033	-0.4967	No
164	MKLN1	70504 1850129	13626	-0.034	-0.4992	No
165	SAMHD1	2350338 5390451	13682	-0.035	-0.5018	No
166	FCGR1	6100176	13693	-0.035	-0.5019	No
167	CYBB	3870020	13722	-0.036	-0.5029	No
168	FAS	4480112 6110040	14042	-0.042	-0.5198	No
169	CXCL9	1570673	14084	-0.043	-0.5215	No
170	CYP8B1	2350369	14260	-0.047	-0.5304	No
171	LPHN1	1400113 3130301	14414	-0.051	-0.5381	No
172	NR1D1	2360471 770746 6590204	14471	-0.053	-0.5405	No
173	PROM1	3170537	14568	-0.056	-0.5450	No
174	CTSS	1740056	14673	-0.059	-0.5499	No
175	CCR1	3440672	14790	-0.063	-0.5554	No
176	ITGB2	6380348	14805	-0.064	-0.5553	No
177	MS4A6C	3870427	14842	-0.065	-0.5565	No
178	EMR1	70136 1500592	14906	-0.068	-0.5590	No
179	AKAP9	510184 2060195 2470136 4280048	15038	-0.073	-0.5652	No
180	NAT8	6520500	15341	-0.089	-0.5805	No
181	MARCO	870056	15368	-0.091	-0.5808	No
182	D17H6S56E-5	4760095	15382	-0.092	-0.5803	No
183	IRGM	6110148 6660685	15434	-0.096	-0.5819	No
184	PSMB10	630504 6510039	15538	-0.102	-0.5862	No
185	CXCL1	2690537	15579	-0.104	-0.5870	No
186	LAPTM5	5550372	15585	-0.105	-0.5859	No
187	TMSB10	2340484	15598	-0.105	-0.5852	No
188	CD7	3140465	15620	-0.106	-0.5850	No
189	NOL1	4570576 4920044	15654	-0.109	-0.5854	No
190	PRM3	4810577	15656	-0.109	-0.5840	No
191	HPXN	3440114	15758	-0.118	-0.5880	No
192	GRN	4050239	15775	-0.119	-0.5874	No
193	G6PC	430093	15785	-0.120	-0.5863	No
194	COL4A1	1740575	15860	-0.127	-0.5887	No
195	1110038F14RIK	1190075	15989	-0.139	-0.5939	No
196	SELPL	1770167	16091	-0.150	-0.5975	No
197	SOCS1	730139	16135	-0.154	-0.5978	No
198	IL18BP	3450128	16244	-0.167	-0.6016	No
199	WARS	2570717 3290139	16248	-0.168	-0.5996	No
200	LCK	3360142	16351	-0.181	-0.6028	No
201	NFKBIA	1570152	16392	-0.187	-0.6026	No
202	CLIC1	110600	16455	-0.194	-0.6034	No
203	RRAS	4150609	16477	-0.197	-0.6020	No
204	VCAM1	2900450	16667	-0.222	-0.6095	No
205	CD53	5550162	16723	-0.232	-0.6095	No
206	IRF8	610161	16794	-0.242	-0.6102	Yes
207	SCD5	5690309 5220332 7040278	16795	-0.242	-0.6071	Yes
208	S100A4	3780113	16825	-0.248	-0.6054	Yes
209	MT2A	6860286	16863	-0.253	-0.6042	Yes
210	CCL5	3710397	16895	-0.258	-0.6025	Yes
211	TAPBP	1980110	16915	-0.261	-0.6002	Yes
212	IRF7	1570605	16971	-0.268	-0.5998	Yes
213	FKBP11	3170575	17079	-0.287	-0.6019	Yes
214	CTSE	2030292	17133	-0.298	-0.6009	Yes
215	CCL7	2650519	17173	-0.305	-0.5991	Yes
216	PTPN1	2650056	17180	-0.306	-0.5955	Yes
217	CD14	5570600	17194	-0.309	-0.5922	Yes
218	PRTN3	6900670	17234	-0.318	-0.5902	Yes
219	PSMB8	2850707	17268	-0.325	-0.5879	Yes
220	FBXO21	6550070	17273	-0.326	-0.5839	Yes
221	D12ERTD647E	5290364	17331	-0.338	-0.5826	Yes
222	ELAC2	3440167 4730546	17429	-0.356	-0.5833	Yes
223	ITPK1	3360056	17517	-0.374	-0.5832	Yes
224	IRF1	2340152 3450592 6290121 6980577	17521	-0.374	-0.5786	Yes
225	TAP1	4050047	17571	-0.387	-0.5762	Yes
226	CYBA	4760739	17579	-0.389	-0.5716	Yes
227	QSCN6	3120441	17590	-0.393	-0.5671	Yes
228	H2-AB1	4230427	17628	-0.407	-0.5639	Yes
229	CFP	2100619	17651	-0.414	-0.5597	Yes
230	SLC25A10	1400609	17655	-0.415	-0.5545	Yes
231	H2-DMB1	4760026	17667	-0.417	-0.5497	Yes
232	SLFN2	3120114	17673	-0.419	-0.5446	Yes
233	LITAF	6940671	17740	-0.443	-0.5425	Yes
234	MT1A	4850164	17747	-0.444	-0.5371	Yes
235	TSPAN4	5050647	17748	-0.445	-0.5313	Yes
236	LGALS3	2120239	17764	-0.451	-0.5263	Yes
237	CTPS	70451 1740132	17780	-0.456	-0.5213	Yes
238	SNX12	4060026	17789	-0.458	-0.5158	Yes
239	IFI35	4230739	17809	-0.464	-0.5108	Yes
240	SERPINA3G	610600	17858	-0.486	-0.5072	Yes
241	ALAS2	6550176	17885	-0.496	-0.5022	Yes
242	VEGFB	5360152	17898	-0.500	-0.4964	Yes
243	TYROBP	2230020	17900	-0.501	-0.4900	Yes
244	PLD3	510041	17915	-0.508	-0.4842	Yes
245	H2-AA	5290673	17922	-0.511	-0.4779	Yes
246	UBE1L	6660242	17930	-0.514	-0.4717	Yes
247	NXN	2350180	18015	-0.562	-0.4690	Yes
248	SAA3P	6510390	18018	-0.563	-0.4619	Yes
249	HP	2940551 6350068	18022	-0.566	-0.4547	Yes
250	S100A6	1690204	18023	-0.566	-0.4474	Yes
251	CD68	6350450	18041	-0.578	-0.4409	Yes
252	GPX3	1340450	18050	-0.585	-0.4338	Yes
253	ISG15	3170093	18067	-0.597	-0.4270	Yes
254	LGALS3BP	840692	18081	-0.606	-0.4199	Yes
255	H2-EB1	2350079	18132	-0.642	-0.4143	Yes
256	CRYL1	1340427	18151	-0.660	-0.4068	Yes
257	CCL4	50368 430047	18176	-0.680	-0.3993	Yes
258	C1QA	5390687	18209	-0.722	-0.3917	Yes
259	SLPI	2120446	18212	-0.723	-0.3825	Yes
260	C1QB	5910292	18220	-0.735	-0.3734	Yes
261	NGP	2640133	18225	-0.739	-0.3641	Yes
262	TFF3	1580129	18227	-0.741	-0.3546	Yes
263	H2-DMA	6290463	18269	-0.809	-0.3464	Yes
264	S100A9	7050528	18285	-0.837	-0.3364	Yes
265	C1QC	5700131	18312	-0.890	-0.3263	Yes
266	LGMN	3610301	18320	-0.907	-0.3150	Yes
267	CTSC	2230739 4670408	18322	-0.907	-0.3034	Yes
268	ELA1	3390167	18327	-0.914	-0.2918	Yes
269	HBB-B2	2450131	18400	-1.007	-0.2827	Yes
270	LTF	6770364	18427	-1.067	-0.2704	Yes
271	PDZK1	2320128	18435	-1.085	-0.2568	Yes
272	SIRPA	130465 5700332	18438	-1.090	-0.2428	Yes
273	CAMP	6290735	18456	-1.123	-0.2293	Yes
274	PLAC8	2900019	18505	-1.382	-0.2140	Yes
275	HES6	540411 6550504	18520	-1.504	-0.1954	Yes
276	KLF2	6860270	18525	-1.525	-0.1759	Yes
277	S100A8	70112	18531	-1.547	-0.1563	Yes
278	FLOT1	1660575 1690040	18533	-1.559	-0.1362	Yes
279	HBA-A1	360435	18571	-2.070	-0.1115	Yes
280	SCOTIN	670332 3450167 6450022	18594	-2.740	-0.0774	Yes
281	CYB561	5080341	18598	-2.891	-0.0402	Yes
282	SLC11A1	940286 2810435 6370647	18601	-3.189	0.0008	Yes