Dataset | Set_03_wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_wtNotch_versus_truncNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | 0.6049309 |
Normalized Enrichment Score (NES) | 1.642366 |
Nominal p-value | 0.0 |
FDR q-value | 0.14169292 |
FWER p-Value | 0.84 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 46 | 1.652 | 0.0371 | Yes | ||
2 | ATP2A2 | 1090075 3990279 | 62 | 1.475 | 0.0717 | Yes | ||
3 | HDAC2 | 4050433 | 161 | 0.999 | 0.0904 | Yes | ||
4 | LBR | 4540671 | 226 | 0.872 | 0.1078 | Yes | ||
5 | TBK1 | 5690338 | 231 | 0.870 | 0.1285 | Yes | ||
6 | RABGAP1 | 5050397 | 232 | 0.869 | 0.1494 | Yes | ||
7 | RBM17 | 870592 | 234 | 0.867 | 0.1701 | Yes | ||
8 | SLC4A1AP | 3190576 | 253 | 0.843 | 0.1894 | Yes | ||
9 | GTF2H2 | 5130358 | 290 | 0.788 | 0.2063 | Yes | ||
10 | DDX21 | 6100446 | 292 | 0.788 | 0.2252 | Yes | ||
11 | SRPK2 | 6380341 | 304 | 0.780 | 0.2433 | Yes | ||
12 | TOP2A | 360717 | 340 | 0.748 | 0.2594 | Yes | ||
13 | CCT4 | 6380161 | 354 | 0.731 | 0.2762 | Yes | ||
14 | CCNH | 3190347 | 360 | 0.727 | 0.2934 | Yes | ||
15 | HSPH1 | 1690017 | 372 | 0.711 | 0.3098 | Yes | ||
16 | MCTS1 | 6130133 | 376 | 0.706 | 0.3266 | Yes | ||
17 | PPP2R5E | 70671 2120056 | 395 | 0.689 | 0.3422 | Yes | ||
18 | EMP1 | 4120438 | 432 | 0.662 | 0.3561 | Yes | ||
19 | SMAD4 | 5670519 | 437 | 0.658 | 0.3717 | Yes | ||
20 | RAP1B | 3710138 | 444 | 0.654 | 0.3870 | Yes | ||
21 | OGT | 2360131 4610333 | 449 | 0.653 | 0.4025 | Yes | ||
22 | RABGGTB | 3120037 | 459 | 0.647 | 0.4175 | Yes | ||
23 | XBP1 | 3840594 | 534 | 0.605 | 0.4280 | Yes | ||
24 | PSMA4 | 4560427 | 565 | 0.585 | 0.4404 | Yes | ||
25 | RAB1A | 2370671 | 637 | 0.543 | 0.4496 | Yes | ||
26 | EXOC2 | 3190132 | 727 | 0.499 | 0.4568 | Yes | ||
27 | DDX20 | 3290348 | 734 | 0.495 | 0.4683 | Yes | ||
28 | UBE2D2 | 4590671 6510446 | 757 | 0.486 | 0.4788 | Yes | ||
29 | PIK3C3 | 6590717 | 768 | 0.483 | 0.4898 | Yes | ||
30 | SLC25A17 | 2100369 | 942 | 0.418 | 0.4905 | Yes | ||
31 | RIPK1 | 3190025 | 948 | 0.416 | 0.5002 | Yes | ||
32 | PCNA | 940754 | 954 | 0.414 | 0.5099 | Yes | ||
33 | FNTA | 70059 | 959 | 0.412 | 0.5195 | Yes | ||
34 | POLD3 | 6400278 | 1013 | 0.388 | 0.5260 | Yes | ||
35 | GTF2H1 | 2570746 2650148 | 1029 | 0.381 | 0.5343 | Yes | ||
36 | UBE2D3 | 3190452 | 1032 | 0.381 | 0.5433 | Yes | ||
37 | PJA2 | 430537 | 1061 | 0.371 | 0.5507 | Yes | ||
38 | PSMD12 | 730044 | 1085 | 0.365 | 0.5582 | Yes | ||
39 | PPP2CB | 5570593 | 1111 | 0.356 | 0.5654 | Yes | ||
40 | MAP3K7 | 6040068 | 1135 | 0.352 | 0.5726 | Yes | ||
41 | TNFSF5IP1 | 2060095 | 1159 | 0.346 | 0.5797 | Yes | ||
42 | BCL2L1 | 1580452 4200152 5420484 | 1257 | 0.321 | 0.5821 | Yes | ||
43 | ELOVL6 | 5340746 | 1352 | 0.293 | 0.5841 | Yes | ||
44 | TMPO | 4050494 | 1451 | 0.266 | 0.5851 | Yes | ||
45 | MAPK14 | 5290731 | 1470 | 0.262 | 0.5904 | Yes | ||
46 | GNL2 | 6620022 | 1492 | 0.257 | 0.5955 | Yes | ||
47 | GTF2B | 6860685 | 1592 | 0.236 | 0.5958 | Yes | ||
48 | MAT2A | 4070026 4730079 6020280 | 1597 | 0.235 | 0.6012 | Yes | ||
49 | SIRT1 | 1190731 | 1727 | 0.212 | 0.5993 | Yes | ||
50 | SUPV3L1 | 1170072 | 1769 | 0.206 | 0.6020 | Yes | ||
51 | TXNRD1 | 6590446 | 1832 | 0.194 | 0.6033 | Yes | ||
52 | STK17B | 130091 | 1884 | 0.184 | 0.6049 | Yes | ||
53 | EML4 | 5700373 | 2020 | 0.165 | 0.6016 | No | ||
54 | FADD | 2360593 4210692 6520019 | 2068 | 0.158 | 0.6028 | No | ||
55 | BIRC2 | 2940435 4730020 | 2252 | 0.132 | 0.5961 | No | ||
56 | PRIM2A | 7000692 | 2415 | 0.114 | 0.5900 | No | ||
57 | CCNA2 | 5290075 | 2458 | 0.110 | 0.5904 | No | ||
58 | RPS7 | 6860113 | 2487 | 0.107 | 0.5914 | No | ||
59 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 2493 | 0.106 | 0.5937 | No | ||
60 | ZDHHC5 | 1690711 | 2523 | 0.104 | 0.5946 | No | ||
61 | PSMC6 | 2810021 | 2601 | 0.097 | 0.5928 | No | ||
62 | ERCC3 | 6900008 | 2624 | 0.095 | 0.5939 | No | ||
63 | GABPB2 | 6130450 7050735 | 2652 | 0.093 | 0.5946 | No | ||
64 | ARFGEF2 | 5550500 | 2699 | 0.089 | 0.5943 | No | ||
65 | JMJD2B | 6350372 6400471 | 2822 | 0.080 | 0.5896 | No | ||
66 | GCNT1 | 940129 1780215 2370253 | 2919 | 0.073 | 0.5862 | No | ||
67 | SMARCA5 | 6620050 | 2938 | 0.072 | 0.5869 | No | ||
68 | FBXL3 | 5910142 | 3010 | 0.067 | 0.5847 | No | ||
69 | MRPL15 | 360390 | 3050 | 0.065 | 0.5841 | No | ||
70 | PPP1CC | 6380300 2510647 | 3072 | 0.063 | 0.5845 | No | ||
71 | SNRPG | 2340551 | 3111 | 0.061 | 0.5839 | No | ||
72 | CORO1C | 4570397 | 3112 | 0.061 | 0.5853 | No | ||
73 | PSMB1 | 2940402 | 3202 | 0.055 | 0.5818 | No | ||
74 | FNDC3A | 2690097 3290044 | 3531 | 0.040 | 0.5650 | No | ||
75 | USP12 | 6130735 6620280 | 3602 | 0.038 | 0.5621 | No | ||
76 | CDC5L | 3130446 3390025 6400204 | 3840 | 0.030 | 0.5500 | No | ||
77 | GOPC | 6620400 | 3902 | 0.029 | 0.5474 | No | ||
78 | WEE1 | 3390070 | 3945 | 0.027 | 0.5458 | No | ||
79 | SSFA2 | 3870133 | 4128 | 0.024 | 0.5365 | No | ||
80 | CDC25C | 2570673 4760161 6520707 | 4287 | 0.021 | 0.5284 | No | ||
81 | SFRS9 | 3800047 | 4412 | 0.019 | 0.5222 | No | ||
82 | RBM27 | 4050603 | 5156 | 0.011 | 0.4822 | No | ||
83 | CDC23 | 3190593 | 5170 | 0.011 | 0.4818 | No | ||
84 | PRKD3 | 5220520 5890519 | 5286 | 0.010 | 0.4758 | No | ||
85 | TCERG1 | 2350551 4540397 5220746 | 5359 | 0.010 | 0.4721 | No | ||
86 | LYN | 6040600 | 5623 | 0.008 | 0.4581 | No | ||
87 | MTIF2 | 2260270 | 5988 | 0.006 | 0.4385 | No | ||
88 | MYC | 380541 4670170 | 6391 | 0.005 | 0.4168 | No | ||
89 | CRK | 1230162 4780128 | 6657 | 0.004 | 0.4025 | No | ||
90 | GGPS1 | 840128 2320215 | 6663 | 0.004 | 0.4024 | No | ||
91 | SPRY2 | 5860184 | 6779 | 0.003 | 0.3962 | No | ||
92 | PLAG1 | 1450142 3870139 6520039 | 6908 | 0.003 | 0.3893 | No | ||
93 | TDG | 2900358 2940079 | 6911 | 0.003 | 0.3893 | No | ||
94 | VEGFC | 5910494 | 7046 | 0.002 | 0.3821 | No | ||
95 | GDI2 | 2370068 | 7071 | 0.002 | 0.3808 | No | ||
96 | NCOA6 | 1780333 6450110 | 7157 | 0.002 | 0.3763 | No | ||
97 | FBXL7 | 6620711 | 7256 | 0.002 | 0.3710 | No | ||
98 | ATG5 | 6200433 5360324 | 7585 | 0.001 | 0.3533 | No | ||
99 | CFLAR | 2320605 6180440 | 8009 | -0.000 | 0.3303 | No | ||
100 | MRPL35 | 1990671 | 8038 | -0.000 | 0.3288 | No | ||
101 | BUB1 | 5390270 | 8455 | -0.002 | 0.3063 | No | ||
102 | MFAP1 | 6660092 | 8800 | -0.003 | 0.2877 | No | ||
103 | XRCC5 | 7100286 | 8889 | -0.003 | 0.2830 | No | ||
104 | FZD1 | 3140215 | 9072 | -0.003 | 0.2733 | No | ||
105 | ACSL3 | 3140195 | 9146 | -0.004 | 0.2694 | No | ||
106 | EPS8 | 7050204 | 9549 | -0.005 | 0.2477 | No | ||
107 | FOSL1 | 430021 | 9620 | -0.005 | 0.2440 | No | ||
108 | CRSP6 | 2940358 | 9653 | -0.005 | 0.2424 | No | ||
109 | ARHGEF2 | 3360577 | 10082 | -0.006 | 0.2194 | No | ||
110 | JAG1 | 3440390 | 10130 | -0.007 | 0.2170 | No | ||
111 | RAB5A | 6520324 | 10133 | -0.007 | 0.2170 | No | ||
112 | CXXC5 | 840010 | 10198 | -0.007 | 0.2137 | No | ||
113 | IPO7 | 2190746 | 10257 | -0.007 | 0.2108 | No | ||
114 | CDK7 | 2640451 | 10864 | -0.009 | 0.1781 | No | ||
115 | CDH11 | 1230133 2100180 4610110 | 10986 | -0.010 | 0.1718 | No | ||
116 | BIRC6 | 70148 | 11020 | -0.010 | 0.1703 | No | ||
117 | CPT1A | 6350093 | 11289 | -0.011 | 0.1560 | No | ||
118 | TIAM2 | 360195 | 11466 | -0.012 | 0.1468 | No | ||
119 | HSPA1L | 4010538 | 11468 | -0.012 | 0.1470 | No | ||
120 | RNF14 | 50402 1340041 6370687 | 11864 | -0.015 | 0.1260 | No | ||
121 | EIF4B | 5390563 5270577 | 12019 | -0.016 | 0.1180 | No | ||
122 | HS3ST3B1 | 380040 | 12112 | -0.016 | 0.1134 | No | ||
123 | NUFIP1 | 6350241 | 12226 | -0.017 | 0.1077 | No | ||
124 | CTGF | 4540577 | 12821 | -0.023 | 0.0761 | No | ||
125 | B4GALT5 | 1230692 | 12879 | -0.024 | 0.0735 | No | ||
126 | UBE2C | 6130017 | 13458 | -0.031 | 0.0430 | No | ||
127 | MTMR4 | 4540524 | 13484 | -0.032 | 0.0424 | No | ||
128 | ANLN | 1780113 2470537 6840047 | 13492 | -0.032 | 0.0427 | No | ||
129 | PAPPA | 4230463 | 13641 | -0.034 | 0.0355 | No | ||
130 | SEH1L | 4590563 | 13695 | -0.035 | 0.0335 | No | ||
131 | MCM3 | 5570068 | 13752 | -0.036 | 0.0313 | No | ||
132 | THRAP3 | 6180309 | 13781 | -0.037 | 0.0307 | No | ||
133 | IL1RL1 | 3990224 6020347 | 13936 | -0.040 | 0.0233 | No | ||
134 | RCC1 | 2480358 | 14031 | -0.042 | 0.0192 | No | ||
135 | FAS | 4480112 6110040 | 14042 | -0.042 | 0.0197 | No | ||
136 | PSMA5 | 5390537 | 14114 | -0.044 | 0.0169 | No | ||
137 | MRPL1 | 430626 3130129 5220152 | 14293 | -0.048 | 0.0084 | No | ||
138 | ADSL | 5570484 | 14599 | -0.057 | -0.0068 | No | ||
139 | EIF3S10 | 1190079 3840176 | 14916 | -0.068 | -0.0223 | No | ||
140 | CLCN7 | 2970095 | 14927 | -0.069 | -0.0212 | No | ||
141 | EPS15 | 4200215 | 14942 | -0.069 | -0.0203 | No | ||
142 | PDGFB | 3060440 6370008 | 14969 | -0.070 | -0.0200 | No | ||
143 | BLZF1 | 630088 | 15231 | -0.083 | -0.0322 | No | ||
144 | BUB3 | 3170546 | 15296 | -0.087 | -0.0335 | No | ||
145 | DLG5 | 450215 | 15582 | -0.104 | -0.0465 | No | ||
146 | ZDHHC16 | 4230390 | 15914 | -0.131 | -0.0613 | No | ||
147 | DNAJA2 | 2630253 6860358 | 15965 | -0.137 | -0.0607 | No | ||
148 | CHST2 | 3180682 | 16052 | -0.147 | -0.0618 | No | ||
149 | SON | 3120148 5860239 7040403 | 16165 | -0.158 | -0.0641 | No | ||
150 | TOP1 | 770471 4060632 6650324 | 16196 | -0.162 | -0.0619 | No | ||
151 | PANX1 | 6550632 | 16375 | -0.184 | -0.0671 | No | ||
152 | ARFGAP1 | 4780364 5390358 | 16383 | -0.186 | -0.0630 | No | ||
153 | HSPA8 | 2120315 1050132 6550746 | 16432 | -0.191 | -0.0610 | No | ||
154 | MID1IP1 | 2570739 | 16441 | -0.192 | -0.0569 | No | ||
155 | FKBP1A | 2450368 | 16447 | -0.193 | -0.0525 | No | ||
156 | USP3 | 2060332 | 16490 | -0.198 | -0.0500 | No | ||
157 | SNIP1 | 5360092 | 16921 | -0.262 | -0.0670 | No | ||
158 | RBM14 | 5340731 5690315 | 17130 | -0.297 | -0.0712 | No | ||
159 | BAG2 | 2900324 | 17243 | -0.320 | -0.0696 | No | ||
160 | LHFPL2 | 450020 | 17668 | -0.418 | -0.0825 | No | ||
161 | TARDBP | 870390 2350093 | 17678 | -0.419 | -0.0730 | No | ||
162 | HSPE1 | 3170438 | 17798 | -0.461 | -0.0683 | No | ||
163 | GIPC1 | 4590348 5570438 5900707 | 17914 | -0.507 | -0.0624 | No | ||
164 | SLC2A1 | 2100609 | 18071 | -0.599 | -0.0565 | No | ||
165 | WNT5B | 5080162 | 18413 | -1.042 | -0.0500 | No | ||
166 | SIRPA | 130465 5700332 | 18438 | -1.090 | -0.0251 | No | ||
167 | KIAA0859 | 510497 770722 1340687 6840711 | 18513 | -1.447 | 0.0056 | No |