Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch.phenotype_wtNotch_versus_truncNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_wtNotch_versus_truncNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | truncNotch |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | -0.7906465 |
| Normalized Enrichment Score (NES) | -1.6335509 |
| Nominal p-value | 0.0037950664 |
| FDR q-value | 0.18845555 |
| FWER p-Value | 0.81 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SLC25A4 | 2360519 | 2446 | 0.111 | -0.1173 | No | ||
| 2 | COL6A1 | 1410670 2940091 6510086 | 2693 | 0.090 | -0.1190 | No | ||
| 3 | SULF1 | 430575 | 4529 | 0.018 | -0.2154 | No | ||
| 4 | ACTA2 | 60008 1230082 | 4559 | 0.017 | -0.2148 | No | ||
| 5 | SPARC | 1690086 | 4792 | 0.015 | -0.2254 | No | ||
| 6 | IL6 | 380133 | 5316 | 0.010 | -0.2522 | No | ||
| 7 | FOSB | 1940142 | 5612 | 0.008 | -0.2670 | No | ||
| 8 | IGFBP3 | 2370500 | 5749 | 0.008 | -0.2734 | No | ||
| 9 | RGS2 | 1090736 | 7779 | 0.000 | -0.3825 | No | ||
| 10 | TMSB4X | 6620114 | 8770 | -0.002 | -0.4354 | No | ||
| 11 | LOX | 5340372 | 9013 | -0.003 | -0.4481 | No | ||
| 12 | THBS2 | 2850136 | 12748 | -0.022 | -0.6461 | No | ||
| 13 | CTGF | 4540577 | 12821 | -0.023 | -0.6471 | No | ||
| 14 | CCL3 | 2810092 | 13522 | -0.032 | -0.6806 | No | ||
| 15 | NNMT | 450471 | 13547 | -0.033 | -0.6777 | No | ||
| 16 | CXCL2 | 610398 | 13668 | -0.035 | -0.6796 | No | ||
| 17 | SERPINE1 | 4210403 | 13832 | -0.038 | -0.6836 | No | ||
| 18 | COL1A2 | 380364 | 14505 | -0.054 | -0.7128 | No | ||
| 19 | COL6A3 | 2640717 4070064 5390717 | 14797 | -0.064 | -0.7202 | No | ||
| 20 | FOS | 1850315 | 14838 | -0.065 | -0.7140 | No | ||
| 21 | NR4A2 | 60273 | 15039 | -0.073 | -0.7153 | No | ||
| 22 | TPM2 | 520735 3870390 | 15138 | -0.078 | -0.7106 | No | ||
| 23 | NFKBIA | 1570152 | 16392 | -0.187 | -0.7539 | Yes | ||
| 24 | IER3 | 5860021 | 17075 | -0.287 | -0.7537 | Yes | ||
| 25 | LOXL1 | 3520537 | 17332 | -0.338 | -0.7239 | Yes | ||
| 26 | NOTCH3 | 3060603 | 17599 | -0.396 | -0.6873 | Yes | ||
| 27 | LAMA4 | 3170647 | 17656 | -0.415 | -0.6369 | Yes | ||
| 28 | FSCN1 | 3450463 | 17949 | -0.522 | -0.5853 | Yes | ||
| 29 | CCL4 | 50368 430047 | 18176 | -0.680 | -0.5099 | Yes | ||
| 30 | TGM2 | 5360452 | 18226 | -0.740 | -0.4173 | Yes | ||
| 31 | TGFBI | 2060446 6900112 | 18366 | -0.957 | -0.3015 | Yes | ||
| 32 | IGFBP7 | 520411 3060110 5290152 | 18450 | -1.108 | -0.1632 | Yes | ||
| 33 | DUSP1 | 6860121 | 18501 | -1.337 | 0.0062 | Yes |
