Details for gene set PENG_RAPAMYCIN

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	wtNotch
GeneSet	PENG_RAPAMYCIN_DN
Enrichment Score (ES)	0.6994178
Normalized Enrichment Score (NES)	1.7014905
Nominal p-value	0.0
FDR q-value	0.01503093
FWER p-Value	0.073

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PGK1	1570494 630300	8	5.004	0.0593	Yes
2	PFKM	1990156 5720168	21	4.511	0.1126	Yes
3	RTN4	50725 630647 870097 870184	96	2.577	0.1393	Yes
4	SLC7A5	3310746	117	2.336	0.1661	Yes
5	TFRC	4050551	123	2.289	0.1932	Yes
6	EIF3S9	2030068 2120044	145	2.103	0.2172	Yes
7	SRM	1850097 2480162	147	2.080	0.2420	Yes
8	SLC29A1	2970379	156	2.041	0.2659	Yes
9	SNRPA1	1050735 6110131	177	1.916	0.2877	Yes
10	ATF5	5670685	304	1.513	0.2990	Yes
11	DDX21	6100446	368	1.350	0.3117	Yes
12	HSPA8	2120315 1050132 6550746	377	1.340	0.3272	Yes
13	TCP1	2450100 5130524	431	1.221	0.3390	Yes
14	C1QBP	3170452	447	1.194	0.3524	Yes
15	ETF1	6770075	456	1.182	0.3661	Yes
16	CYC1	2850546	498	1.122	0.3773	Yes
17	CCT6A	2350368	512	1.102	0.3897	Yes
18	IDH3A	460332	517	1.096	0.4026	Yes
19	ASNS	110368 7100687	551	1.051	0.4133	Yes
20	PSMB5	6290242	586	1.023	0.4237	Yes
21	AATF	5220575	587	1.023	0.4359	Yes
22	GM2A	430095	595	1.016	0.4477	Yes
23	PSMD14	5690593	629	0.977	0.4576	Yes
24	NARS	1660722	652	0.957	0.4678	Yes
25	FASN	430717	668	0.944	0.4783	Yes
26	RARS	380390	675	0.941	0.4892	Yes
27	UBE2M	2450215	711	0.919	0.4983	Yes
28	CTPS	70451 1740132	717	0.912	0.5089	Yes
29	PA2G4	2030463	742	0.894	0.5183	Yes
30	NDUFS3	1690136 5340528	777	0.874	0.5269	Yes
31	CCT4	6380161	796	0.856	0.5361	Yes
32	CYCS	2030072	807	0.851	0.5457	Yes
33	DDX3X	2190020	877	0.789	0.5514	Yes
34	MRPL12	3120112	907	0.760	0.5589	Yes
35	GCN5L2	2340609	946	0.720	0.5655	Yes
36	NOL1	4570576 4920044	994	0.688	0.5711	Yes
37	UBE2L3	1690707 5900242	997	0.686	0.5792	Yes
38	DHCR24	840600 1050672 6290097	1007	0.680	0.5869	Yes
39	BCS1L	5360102	1018	0.674	0.5944	Yes
40	USP10	2030736 2450333	1032	0.665	0.6016	Yes
41	EIF2B2	4290048	1096	0.629	0.6057	Yes
42	CCT5	1050670	1103	0.626	0.6129	Yes
43	CCNC	3390750	1257	0.556	0.6112	Yes
44	TIMM17A	130092	1293	0.539	0.6157	Yes
45	ADRM1	670333 5690162	1306	0.536	0.6215	Yes
46	NOL5A	5570139	1376	0.507	0.6238	Yes
47	NME1	770014	1389	0.502	0.6292	Yes
48	CSE1L	3850086	1425	0.489	0.6331	Yes
49	PSMD8	630142	1462	0.473	0.6368	Yes
50	PSMC2	7040010	1472	0.470	0.6419	Yes
51	NMT1	5810152	1478	0.467	0.6472	Yes
52	PITPNB	5130039	1482	0.464	0.6526	Yes
53	SCD	2680441	1517	0.450	0.6561	Yes
54	SF3A3	6660603	1532	0.442	0.6607	Yes
55	ETFA	50347 5690040 6370044	1537	0.441	0.6657	Yes
56	TOMM40	6110017	1541	0.439	0.6708	Yes
57	SLC3A2	5270358	1607	0.425	0.6723	Yes
58	GOT2	4570164 5220450	1609	0.424	0.6774	Yes
59	HSPE1	3170438	1661	0.403	0.6794	Yes
60	CCT2	1690113	1676	0.397	0.6834	Yes
61	HYOU1	3060465	1705	0.390	0.6865	Yes
62	MORF4L2	6450133	1725	0.384	0.6901	Yes
63	RAE1	7050121	1786	0.368	0.6912	Yes
64	PGAM1	2570133	1830	0.354	0.6931	Yes
65	GLO1	7040692	1851	0.348	0.6962	Yes
66	DAP3	1660528 2120039 5420593	1868	0.343	0.6994	Yes
67	EIF4G1	4070446	2065	0.292	0.6923	No
68	MRPS12	4210707 6110341	2066	0.291	0.6958	No
69	IDH3B	5690070	2168	0.268	0.6935	No
70	FKBP4	870035	2276	0.242	0.6906	No
71	AK2	4590458 4760195 6110097	2317	0.233	0.6912	No
72	EIF4G2	3800575 6860184	2335	0.229	0.6930	No
73	WBSCR22	3130070 4120551 5570433	2412	0.216	0.6915	No
74	YARS	70739	2440	0.209	0.6925	No
75	PPP2R2A	2900014 5700575	2484	0.200	0.6925	No
76	EIF2B4	5270082	2491	0.200	0.6946	No
77	ATP5G3	4230551	2541	0.189	0.6942	No
78	SDHB	3120398 4780113 3710435	2612	0.178	0.6925	No
79	PRDX3	1690035	2643	0.174	0.6930	No
80	TRIP13	6860341	2654	0.172	0.6945	No
81	MLF2	1940176	2672	0.170	0.6956	No
82	AHSA1	2030520	2707	0.164	0.6957	No
83	EBNA1BP2	50369 1400433 6040019	2805	0.152	0.6923	No
84	PTBP1	4070736	2959	0.133	0.6856	No
85	HSPA5	5130671	3005	0.130	0.6847	No
86	TUBG1	3140204	3057	0.124	0.6834	No
87	INPP5E	6100619	3128	0.118	0.6810	No
88	ATP1B3	6040128	3135	0.118	0.6821	No
89	NDUFA9	2260280	3156	0.115	0.6824	No
90	COX7B	2340504	3213	0.110	0.6807	No
91	RBBP6	2320129	3332	0.098	0.6755	No
92	MAPKAPK3	630520	3350	0.097	0.6757	No
93	BMP1	380594 2940576 3710593	3396	0.092	0.6744	No
94	TARS	50440 1340086	3432	0.090	0.6735	No
95	EBP	2760292	3611	0.077	0.6648	No
96	CDC25A	3800184	3629	0.076	0.6648	No
97	KPNA3	7040088	3637	0.075	0.6653	No
98	GORASP2	2970059 4060309 7040706	3680	0.072	0.6639	No
99	ICT1	430138	3693	0.071	0.6641	No
100	WNT10B	510050	3852	0.061	0.6563	No
101	ACAT2	2680400 3610440	4095	0.050	0.6437	No
102	SLC39A14	670300 1400093 1990711	4199	0.046	0.6387	No
103	AMD1	6290128	4257	0.044	0.6361	No
104	VCP	5340168	4384	0.041	0.6298	No
105	DNAJA1	1660010 2320358 6840136	4431	0.039	0.6278	No
106	ARMET	5130670	4591	0.036	0.6196	No
107	NP	2630577 3120142 5670068 6290039	4866	0.030	0.6051	No
108	ARF1	3840291	4896	0.029	0.6039	No
109	SLC1A5	670133 3140020	5020	0.027	0.5975	No
110	CTSC	2230739 4670408	5105	0.026	0.5933	No
111	PPIB	4280450	5152	0.025	0.5911	No
112	RAB1A	2370671	5240	0.024	0.5866	No
113	GCDH	2190324 4280347	6472	0.013	0.5201	No
114	PICALM	1940280	6478	0.013	0.5199	No
115	IDI1	1450736	6638	0.012	0.5115	No
116	COPB2	610154	6925	0.010	0.4961	No
117	TDG	2900358 2940079	7019	0.010	0.4912	No
118	SREBF1	4780333	7039	0.010	0.4902	No
119	GTF2A2	2230184	7512	0.008	0.4647	No
120	CAPZA2	110427 4590064	8068	0.005	0.4347	No
121	CALU	2680403 3520056 4610348 5720176 6130121	8093	0.005	0.4335	No
122	PTDSS1	6020215	8164	0.005	0.4297	No
123	HCCS	670397 3170341	8307	0.005	0.4221	No
124	ATP6V0C	1780609	8640	0.003	0.4041	No
125	PTRF	2260204	8890	0.002	0.3907	No
126	RTCD1	7000041	8974	0.002	0.3862	No
127	PSMD5	3940139 4570041	9265	0.001	0.3705	No
128	IFI30	730309 2940500	9273	0.001	0.3701	No
129	WDR18	6020102	9555	0.000	0.3549	No
130	BTK	3130044	9841	-0.000	0.3394	No
131	PPIF	1740059	10271	-0.002	0.3162	No
132	ACVRL1	3290600	10273	-0.002	0.3162	No
133	BYSL	3170110	11050	-0.004	0.2742	No
134	PHB	2260739	11137	-0.004	0.2696	No
135	POLR2B	3780138	11790	-0.007	0.2343	No
136	P2RX5	5570427 6130435	12021	-0.008	0.2219	No
137	SYNCRIP	1690195 3140113 4670279	12143	-0.009	0.2155	No
138	MYCBP	4280528	12461	-0.010	0.1984	No
139	CHUK	7050736	12475	-0.010	0.1978	No
140	PAPOLA	4200286 4850112	12665	-0.011	0.1877	No
141	EEF1E1	4540711	13040	-0.014	0.1676	No
142	BCAP31	1190520	13245	-0.016	0.1567	No
143	RPS26	510139	13584	-0.019	0.1386	No
144	NUP98	2850465	13855	-0.023	0.1243	No
145	MMP15	5900717	14779	-0.045	0.0747	No
146	PSMD11	2340538 6510053	14841	-0.047	0.0720	No
147	RNASEH1	3840575	15130	-0.061	0.0571	No
148	COX11	1580121	15191	-0.066	0.0547	No
149	EXTL3	540309 3130215 5860500	15213	-0.067	0.0543	No
150	S100A4	3780113	15762	-0.116	0.0260	No
151	GSPT1	5420050	15947	-0.141	0.0177	No
152	ALDH4A1	2450450	15995	-0.147	0.0169	No
153	TIMM44	4670746 4730050	16164	-0.173	0.0099	No
154	UCHL1	1230066	16242	-0.183	0.0079	No
155	HSPA4	1050170 3450309	16253	-0.185	0.0095	No
156	PTPN1	2650056	16440	-0.219	0.0021	No
157	XPO6	3940019	16688	-0.262	-0.0082	No
158	RABGGTB	3120037	16702	-0.265	-0.0057	No
159	CHERP	1240594	16703	-0.266	-0.0025	No
160	LIMK2	2650446 4050164	16797	-0.284	-0.0042	No
161	NXF1	1570377	16945	-0.323	-0.0083	No
162	EMP3	1500722 1570039	16956	-0.325	-0.0050	No
163	JTB	6980400	17253	-0.435	-0.0158	No
164	SQLE	50180 940092	17508	-0.548	-0.0230	No
165	RAB14	6860139	17570	-0.576	-0.0195	No
166	NPM3	3610300	17764	-0.693	-0.0217	No
167	PIP5K1A	4560672	18133	-1.039	-0.0292	No
168	GTF3C1	1990368 4210037	18138	-1.043	-0.0170	No
169	CDK4	540075 4540600	18158	-1.075	-0.0052	No
170	CD47	1850603	18214	-1.182	0.0060	No
171	XBP1	3840594	18277	-1.320	0.0184	No