Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | CHEN_HOXA5_TARGETS_UP |
Enrichment Score (ES) | -0.6143991 |
Normalized Enrichment Score (NES) | -1.5459524 |
Nominal p-value | 0.0 |
FDR q-value | 0.29226315 |
FWER p-Value | 0.997 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NFIL3 | 4070377 | 239 | 1.732 | 0.0336 | No | ||
2 | CEBPB | 2970019 | 282 | 1.602 | 0.0743 | No | ||
3 | ASNS | 110368 7100687 | 551 | 1.051 | 0.0880 | No | ||
4 | JOSD3 | 1110543 | 1089 | 0.635 | 0.0760 | No | ||
5 | NUPL1 | 360273 6770100 | 1749 | 0.377 | 0.0505 | No | ||
6 | ZCCHC8 | 2260332 2350487 | 1808 | 0.360 | 0.0570 | No | ||
7 | NEK1 | 4570059 | 1969 | 0.317 | 0.0568 | No | ||
8 | KIN | 6550014 | 2049 | 0.296 | 0.0605 | No | ||
9 | STC2 | 4920601 | 2571 | 0.185 | 0.0373 | No | ||
10 | ZCCHC6 | 4590446 6860091 | 2976 | 0.132 | 0.0190 | No | ||
11 | RBBP6 | 2320129 | 3332 | 0.098 | 0.0024 | No | ||
12 | STRN3 | 1450093 6200685 | 3486 | 0.086 | -0.0036 | No | ||
13 | CASP3 | 6620397 | 3553 | 0.081 | -0.0050 | No | ||
14 | DMTF1 | 5910047 1570497 2480100 6620239 | 3632 | 0.076 | -0.0072 | No | ||
15 | LIG4 | 6660035 | 3720 | 0.069 | -0.0100 | No | ||
16 | SDCCAG1 | 870202 3520364 4070180 5360647 | 3836 | 0.062 | -0.0146 | No | ||
17 | SEC31A | 2060739 4730048 | 3853 | 0.061 | -0.0138 | No | ||
18 | SNX16 | 870446 | 4050 | 0.052 | -0.0230 | No | ||
19 | BIRC2 | 2940435 4730020 | 4458 | 0.039 | -0.0440 | No | ||
20 | TNFRSF10B | 940671 1500451 6550768 6900500 | 4571 | 0.036 | -0.0491 | No | ||
21 | TSC22D1 | 1340739 6040181 | 4573 | 0.036 | -0.0482 | No | ||
22 | ARID4B | 730754 6660026 | 4881 | 0.030 | -0.0640 | No | ||
23 | DAAM1 | 1500273 | 4892 | 0.030 | -0.0638 | No | ||
24 | NRBF2 | 6110672 | 5000 | 0.027 | -0.0688 | No | ||
25 | TANK | 1090020 2060458 2370400 | 5300 | 0.023 | -0.0844 | No | ||
26 | RIPK2 | 5050072 6290632 | 5362 | 0.023 | -0.0871 | No | ||
27 | IER2 | 2030008 | 5500 | 0.021 | -0.0939 | No | ||
28 | DLX2 | 2320438 4200673 | 5522 | 0.021 | -0.0945 | No | ||
29 | SNAI2 | 2100519 | 5558 | 0.020 | -0.0958 | No | ||
30 | PRPF3 | 2510435 2940593 3610113 5390722 | 5742 | 0.019 | -0.1052 | No | ||
31 | CCNL1 | 130273 | 6069 | 0.016 | -0.1225 | No | ||
32 | DUSP8 | 6650039 | 6131 | 0.015 | -0.1254 | No | ||
33 | CCNT2 | 2100390 4150563 | 6133 | 0.015 | -0.1250 | No | ||
34 | ZNF35 | 670156 | 6173 | 0.015 | -0.1267 | No | ||
35 | PTGS2 | 2510301 3170369 | 6277 | 0.014 | -0.1319 | No | ||
36 | ZNF3 | 1770193 2320047 2570273 | 6922 | 0.010 | -0.1665 | No | ||
37 | KLF10 | 4850056 | 6993 | 0.010 | -0.1700 | No | ||
38 | TDG | 2900358 2940079 | 7019 | 0.010 | -0.1711 | No | ||
39 | PTN | 5910161 | 7088 | 0.009 | -0.1746 | No | ||
40 | AKAP10 | 2630504 5910577 | 7651 | 0.007 | -0.2048 | No | ||
41 | ATF3 | 1940546 | 7719 | 0.007 | -0.2082 | No | ||
42 | CAB39 | 5720471 | 7869 | 0.006 | -0.2161 | No | ||
43 | CDK7 | 2640451 | 8024 | 0.006 | -0.2243 | No | ||
44 | GEM | 5290082 | 8124 | 0.005 | -0.2295 | No | ||
45 | CRY1 | 6770039 | 8163 | 0.005 | -0.2315 | No | ||
46 | RBM15 | 4760113 730286 | 8354 | 0.004 | -0.2416 | No | ||
47 | ZRF1 | 6020181 6510484 | 8484 | 0.004 | -0.2485 | No | ||
48 | ZNF228 | 6020397 | 8540 | 0.004 | -0.2514 | No | ||
49 | CTH | 1190332 5290139 | 8577 | 0.004 | -0.2532 | No | ||
50 | CLEC4A | 2470292 | 8623 | 0.003 | -0.2556 | No | ||
51 | KIF18A | 4610458 | 8777 | 0.003 | -0.2638 | No | ||
52 | CENPC1 | 610273 | 8796 | 0.003 | -0.2647 | No | ||
53 | MAFF | 4850577 5720286 | 8999 | 0.002 | -0.2756 | No | ||
54 | PTPN2 | 130315 | 9056 | 0.002 | -0.2786 | No | ||
55 | GAD1 | 2360035 3140167 | 9223 | 0.001 | -0.2875 | No | ||
56 | CLK1 | 1780551 2100102 2340347 2480347 | 9242 | 0.001 | -0.2884 | No | ||
57 | SNX5 | 1570021 6860609 | 9427 | 0.001 | -0.2984 | No | ||
58 | TIPARP | 50397 | 9437 | 0.001 | -0.2988 | No | ||
59 | CARS | 460441 3140341 | 9474 | 0.001 | -0.3008 | No | ||
60 | TRPC1 | 3120189 4210537 | 9488 | 0.001 | -0.3015 | No | ||
61 | F3 | 2940180 | 9553 | 0.000 | -0.3049 | No | ||
62 | FOSL2 | 870044 1230427 6520433 | 9576 | 0.000 | -0.3061 | No | ||
63 | HLX1 | 4250102 | 9683 | 0.000 | -0.3118 | No | ||
64 | IFI16 | 6520601 | 9777 | -0.000 | -0.3169 | No | ||
65 | PTBP2 | 1240398 | 10138 | -0.001 | -0.3363 | No | ||
66 | TBX3 | 2570672 | 10327 | -0.002 | -0.3464 | No | ||
67 | HRH1 | 840100 | 10572 | -0.003 | -0.3596 | No | ||
68 | RBM5 | 3520402 5270121 | 10792 | -0.003 | -0.3713 | No | ||
69 | TPTE | 580609 630400 3710619 4610161 | 11101 | -0.004 | -0.3879 | No | ||
70 | CREB5 | 2320368 | 11672 | -0.006 | -0.4186 | No | ||
71 | DSCR1 | 4540048 6220039 | 11835 | -0.007 | -0.4272 | No | ||
72 | WAC | 5340390 5910164 | 11992 | -0.008 | -0.4354 | No | ||
73 | FOSB | 1940142 | 12055 | -0.008 | -0.4385 | No | ||
74 | TMEFF1 | 2680100 | 12083 | -0.008 | -0.4398 | No | ||
75 | JMJD1C | 940575 2120025 | 12357 | -0.010 | -0.4543 | No | ||
76 | TUFT1 | 540047 2370010 | 12414 | -0.010 | -0.4571 | No | ||
77 | POLR3F | 1570735 4010494 | 12536 | -0.011 | -0.4633 | No | ||
78 | PSPC1 | 1660017 | 12684 | -0.011 | -0.4710 | No | ||
79 | MARCH7 | 3800020 6620168 | 12703 | -0.011 | -0.4716 | No | ||
80 | PMAIP1 | 1400717 5360047 5900039 | 12864 | -0.013 | -0.4800 | No | ||
81 | NSUN6 | 3830487 | 12963 | -0.013 | -0.4849 | No | ||
82 | SUHW4 | 7000075 | 13332 | -0.016 | -0.5044 | No | ||
83 | AGTPBP1 | 1990735 | 13437 | -0.017 | -0.5095 | No | ||
84 | SOX30 | 2690725 4730309 | 13594 | -0.019 | -0.5175 | No | ||
85 | IFRD1 | 4590215 | 13681 | -0.020 | -0.5216 | No | ||
86 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 13796 | -0.022 | -0.5272 | No | ||
87 | BDKRB1 | 730592 | 13903 | -0.024 | -0.5323 | No | ||
88 | LIF | 1410373 2060129 3990338 | 13953 | -0.024 | -0.5343 | No | ||
89 | BIRC3 | 6550411 | 14045 | -0.026 | -0.5385 | No | ||
90 | CNOT4 | 2320242 6760706 | 14178 | -0.028 | -0.5449 | No | ||
91 | EIF5 | 6380750 | 14406 | -0.033 | -0.5563 | No | ||
92 | INTS6 | 6040736 7570767 | 14476 | -0.035 | -0.5591 | No | ||
93 | JUN | 840170 | 14517 | -0.036 | -0.5603 | No | ||
94 | FNBP4 | 1740139 7050113 | 14577 | -0.038 | -0.5625 | No | ||
95 | SPATA5L1 | 6290692 | 14695 | -0.041 | -0.5677 | No | ||
96 | FOS | 1850315 | 14961 | -0.053 | -0.5806 | No | ||
97 | ARIH1 | 6900025 | 14994 | -0.054 | -0.5809 | No | ||
98 | PCTK2 | 5700673 | 15043 | -0.057 | -0.5820 | No | ||
99 | DCLRE1C | 1450041 2360091 3290671 3390739 | 15155 | -0.064 | -0.5862 | No | ||
100 | CHD9 | 430037 2570129 5420398 | 15220 | -0.068 | -0.5879 | No | ||
101 | SCG5 | 4390328 | 15223 | -0.068 | -0.5862 | No | ||
102 | PPP1R12A | 4070066 4590162 | 15262 | -0.070 | -0.5863 | No | ||
103 | TBK1 | 5690338 | 15264 | -0.071 | -0.5845 | No | ||
104 | RNF111 | 2970072 3140112 5130647 | 15427 | -0.084 | -0.5910 | No | ||
105 | RBM39 | 4230458 6450280 | 15747 | -0.115 | -0.6052 | No | ||
106 | CNOT2 | 520546 2060397 4610543 5550113 | 15806 | -0.123 | -0.6051 | No | ||
107 | CLK4 | 3440484 3610156 | 15937 | -0.139 | -0.6084 | No | ||
108 | ING3 | 110438 2060390 | 15975 | -0.145 | -0.6065 | No | ||
109 | KLF5 | 3840348 | 16019 | -0.150 | -0.6048 | No | ||
110 | SAT1 | 4570463 | 16198 | -0.177 | -0.6096 | Yes | ||
111 | KLF6 | 110541 5360026 | 16225 | -0.181 | -0.6062 | Yes | ||
112 | TNFRSF9 | 2510400 6650484 | 16332 | -0.197 | -0.6067 | Yes | ||
113 | CREM | 840156 6380438 6660041 6660168 | 16364 | -0.204 | -0.6029 | Yes | ||
114 | SEC24A | 1230288 | 16401 | -0.209 | -0.5992 | Yes | ||
115 | DPP8 | 3120136 | 16600 | -0.248 | -0.6032 | Yes | ||
116 | IRF7 | 1570605 | 16675 | -0.260 | -0.6003 | Yes | ||
117 | GADD45B | 2350408 | 16698 | -0.265 | -0.5943 | Yes | ||
118 | RABGGTB | 3120037 | 16702 | -0.265 | -0.5874 | Yes | ||
119 | RCHY1 | 3800739 | 16998 | -0.340 | -0.5942 | Yes | ||
120 | SETDB1 | 840093 | 17007 | -0.343 | -0.5855 | Yes | ||
121 | RELB | 1400048 | 17053 | -0.356 | -0.5783 | Yes | ||
122 | RYBP | 60746 | 17081 | -0.366 | -0.5700 | Yes | ||
123 | PRKRIP1 | 4280746 6100390 | 17155 | -0.393 | -0.5633 | Yes | ||
124 | TAF1A | 2510707 | 17209 | -0.416 | -0.5551 | Yes | ||
125 | TLK2 | 1170161 | 17304 | -0.456 | -0.5479 | Yes | ||
126 | NCOA3 | 4540195 | 17435 | -0.516 | -0.5411 | Yes | ||
127 | SFPQ | 4760110 | 17474 | -0.532 | -0.5288 | Yes | ||
128 | FBXO38 | 2570095 | 17612 | -0.597 | -0.5202 | Yes | ||
129 | JUNB | 4230048 | 17646 | -0.614 | -0.5055 | Yes | ||
130 | BACH1 | 290195 | 17652 | -0.618 | -0.4892 | Yes | ||
131 | BCL10 | 2360397 | 17750 | -0.680 | -0.4761 | Yes | ||
132 | FEM1C | 60300 6130717 6980164 | 17881 | -0.772 | -0.4624 | Yes | ||
133 | NFKBIA | 1570152 | 17914 | -0.797 | -0.4428 | Yes | ||
134 | PELI1 | 3870215 6900040 | 18018 | -0.899 | -0.4242 | Yes | ||
135 | MARK3 | 2370450 | 18042 | -0.929 | -0.4005 | Yes | ||
136 | NFKBIE | 580390 2190086 | 18321 | -1.432 | -0.3771 | Yes | ||
137 | NEDD9 | 1740373 4230053 | 18330 | -1.454 | -0.3385 | Yes | ||
138 | ARNTL | 3170463 | 18352 | -1.518 | -0.2988 | Yes | ||
139 | MCL1 | 1660672 | 18366 | -1.559 | -0.2577 | Yes | ||
140 | TNFAIP3 | 2900142 | 18472 | -2.065 | -0.2079 | Yes | ||
141 | ETS2 | 360451 | 18475 | -2.094 | -0.1518 | Yes | ||
142 | DUSP6 | 5910286 7100070 | 18498 | -2.291 | -0.0914 | Yes | ||
143 | EGR1 | 4610347 | 18597 | -3.640 | 0.0010 | Yes |