Details for gene set BRENTANI

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	BRENTANI_SIGNALING
Enrichment Score (ES)	-0.6183805
Normalized Enrichment Score (NES)	-1.5607758
Nominal p-value	0.0
FDR q-value	0.29264018
FWER p-Value	0.985

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP3K7IP1	2120095 5890452 6040167	78	2.745	0.0483	No
2	STAT5A	2680458	844	0.819	0.0225	No
3	ITGA9	670180	1015	0.675	0.0263	No
4	IL12RB1	2230338 5420053	1099	0.628	0.0338	No
5	MAPKAPK2	2850500	1108	0.621	0.0452	No
6	JAK3	70347 3290008	1394	0.500	0.0394	No
7	CXCL1	2690537	1456	0.476	0.0452	No
8	NOTCH3	3060603	1514	0.451	0.0507	No
9	TYK2	1660465 1740736	1638	0.411	0.0519	No
10	IL10	2340685 2640541 2850403 6590286	1724	0.384	0.0547	No
11	MAPK13	6760215	1777	0.370	0.0589	No
12	HRAS	1980551	2087	0.286	0.0477	No
13	ITGB7	4670619	2171	0.268	0.0483	No
14	SMO	5340538 6350132	2191	0.263	0.0523	No
15	STAT6	1190010 5720019	2231	0.254	0.0550	No
16	JAG2	1500341	2337	0.229	0.0537	No
17	MYD88	2100717	2345	0.227	0.0577	No
18	ABL1	1050593 2030050 4010114	2358	0.225	0.0613	No
19	TNFSF13	2650170	2554	0.188	0.0544	No
20	TYRO3	3130193	2599	0.180	0.0554	No
21	ROCK1	130044	2627	0.176	0.0573	No
22	MAP2K4	5130133	2655	0.172	0.0592	No
23	MAPK10	6110193	3099	0.121	0.0375	No
24	NOTCH4	2450040 6370707	3193	0.112	0.0346	No
25	TNF	6650603	3230	0.108	0.0347	No
26	SUFU	6650181	3461	0.088	0.0239	No
27	ZAP70	1410494 2260504	3498	0.085	0.0236	No
28	TNFSF4	3940594	3805	0.064	0.0082	No
29	ITGA3	4570427	3952	0.057	0.0014	No
30	ERG	50154 1770739	3953	0.057	0.0025	No
31	REL	360707	3994	0.055	0.0014	No
32	APC	3850484 5860722	4223	0.045	-0.0101	No
33	CAMK4	1690091	4383	0.041	-0.0180	No
34	IL1B	2640364	4444	0.039	-0.0205	No
35	WNT5A	840685 3120152	4456	0.039	-0.0203	No
36	BIRC2	2940435 4730020	4458	0.039	-0.0196	No
37	INHA	6100102	4527	0.037	-0.0226	No
38	MAP2K2	4590601	4558	0.036	-0.0235	No
39	TNFRSF10B	940671 1500451 6550768 6900500	4571	0.036	-0.0235	No
40	DLG1	2630091 6020286	4618	0.035	-0.0253	No
41	SOS1	7050338	4675	0.034	-0.0277	No
42	ITGB5	70129	4915	0.029	-0.0401	No
43	RASA1	1240315	4972	0.028	-0.0426	No
44	ITGA4	2470739	4977	0.028	-0.0423	No
45	MPL	2360253	5021	0.027	-0.0441	No
46	ILK	870601 4480180	5070	0.026	-0.0462	No
47	MAPK7	5670079 6100128	5255	0.024	-0.0557	No
48	TANK	1090020 2060458 2370400	5300	0.023	-0.0577	No
49	IL13	7040021	5301	0.023	-0.0572	No
50	MAPK11	130452 3120440 3610465	5433	0.022	-0.0639	No
51	WNT1	4780148	5605	0.020	-0.0728	No
52	GRB14	510035 3060369	5641	0.020	-0.0743	No
53	PTCH2	2900092	5694	0.019	-0.0768	No
54	CXCL2	610398	5695	0.019	-0.0764	No
55	MAP2K7	2260086	5805	0.018	-0.0820	No
56	MUSK	1190113	5830	0.018	-0.0829	No
57	MAS1	2650600	5880	0.017	-0.0853	No
58	ATM	3610110 4050524	6095	0.015	-0.0966	No
59	MCC	620750	6191	0.015	-0.1014	No
60	ITGAM	1190373	6399	0.013	-0.1124	No
61	ARHGAP6	2060121	7460	0.008	-0.1697	No
62	TTK	3800129	7469	0.008	-0.1700	No
63	RAN	2260446 4590647	7473	0.008	-0.1700	No
64	MAPKAPK5	2510601	7528	0.007	-0.1728	No
65	IGFBP3	2370500	7579	0.007	-0.1754	No
66	AKT1	5290746	7820	0.006	-0.1882	No
67	WNT4	4150619	7931	0.006	-0.1941	No
68	ARHGEF12	3990195	7948	0.006	-0.1948	No
69	IFNB1	1400142	8094	0.005	-0.2026	No
70	MAP2K1	840739	8448	0.004	-0.2217	No
71	NRAS	6900577	8451	0.004	-0.2217	No
72	CALM1	380128	8853	0.003	-0.2434	No
73	WNT2	4610020	9301	0.001	-0.2676	No
74	ARHGEF16	3990372	9503	0.001	-0.2785	No
75	NCK1	6200575 6510050	9651	0.000	-0.2864	No
76	SKIL	1090364	9740	-0.000	-0.2912	No
77	BTK	3130044	9841	-0.000	-0.2966	No
78	MAPK4	870142	9905	-0.001	-0.3000	No
79	YWHAE	5310435	10135	-0.001	-0.3124	No
80	IGFBP1	5720435	10359	-0.002	-0.3244	No
81	MAP3K12	2470373 6420162	10931	-0.004	-0.3553	No
82	SRC	580132	11138	-0.004	-0.3664	No
83	RAP1A	1090025	11438	-0.006	-0.3825	No
84	AKT2	3850541 3870519	11856	-0.007	-0.4050	No
85	MAP3K4	5720041	12120	-0.008	-0.4191	No
86	IRS1	1190204	12178	-0.009	-0.4220	No
87	ROS1	1090019	12207	-0.009	-0.4233	No
88	NF1	6980433	12548	-0.011	-0.4416	No
89	ABL2	580021	12675	-0.011	-0.4482	No
90	JAG1	3440390	12827	-0.012	-0.4561	No
91	IFNG	5670592	13089	-0.014	-0.4700	No
92	ITGAX	6130524	13249	-0.016	-0.4783	No
93	IL15	4560332 5860438	13402	-0.017	-0.4862	No
94	ITGAE	4210632 4670239 5340253 5420746 5690154 5700685 6770154	13744	-0.021	-0.5043	No
95	SYK	6940133	13759	-0.022	-0.5046	No
96	PTPRK	1450433 2640142	13777	-0.022	-0.5051	No
97	MAP3K5	6020041 6380162	13797	-0.022	-0.5057	No
98	CXCL12	580546 4150750 4570068	13826	-0.022	-0.5068	No
99	IFNAR1	4730672	13949	-0.024	-0.5130	No
100	ITGA7	1230739	13958	-0.024	-0.5129	No
101	SHC1	2900731 3170504 6520537	14167	-0.028	-0.5237	No
102	MAP2K3	5570193	14524	-0.036	-0.5423	No
103	STAT5B	6200026	14758	-0.044	-0.5541	No
104	MAPK12	450022 1340717 7050484	14805	-0.046	-0.5557	No
105	TNFRSF1B	3990035 5860372	14806	-0.046	-0.5548	No
106	VIPR1	2480292 5720288 6760537	14890	-0.050	-0.5584	No
107	MAPK1	3190193 6200253	14896	-0.050	-0.5577	No
108	BCR	2260020 4230180 6040195	15009	-0.055	-0.5627	No
109	ITGB3	5270463	15056	-0.057	-0.5641	No
110	ITGAV	2340020	15086	-0.059	-0.5645	No
111	ARHGAP1	2810010 5270064	15174	-0.065	-0.5680	No
112	ITGA5	5550520	15331	-0.075	-0.5750	No
113	IKBKG	3450092 3840377 6590592	15354	-0.077	-0.5747	No
114	SFN	6290301 7510608	15508	-0.091	-0.5813	No
115	ITGB4	1740021 3840482	15518	-0.092	-0.5800	No
116	IL18R1	270546	15602	-0.100	-0.5826	No
117	MAP2K5	2030440	16064	-0.156	-0.6046	No
118	MAP3K8	2940286	16098	-0.161	-0.6033	No
119	JAK1	5910746	16124	-0.165	-0.6015	No
120	GRB7	2100471	16166	-0.173	-0.6004	No
121	FYN	2100468 4760520 4850687	16182	-0.174	-0.5979	No
122	CRK	1230162 4780128	16356	-0.203	-0.6034	No
123	IL2RB	4730072	16634	-0.253	-0.6135	Yes
124	ITGB1	5080156 6270528	16711	-0.267	-0.6125	Yes
125	RGS16	780091	16741	-0.273	-0.6089	Yes
126	MAP4K4	2360059	16877	-0.307	-0.6103	Yes
127	RELA	3830075	16981	-0.335	-0.6095	Yes
128	RAF1	1770600	16999	-0.340	-0.6039	Yes
129	RELB	1400048	17053	-0.356	-0.6000	Yes
130	PTEN	3390064	17072	-0.362	-0.5940	Yes
131	PIK3C3	6590717	17077	-0.365	-0.5872	Yes
132	IFNAR2	4070687 7100484	17098	-0.373	-0.5812	Yes
133	ITGB2	6380348	17157	-0.394	-0.5768	Yes
134	TNFRSF4	6840056	17211	-0.418	-0.5717	Yes
135	MKNK1	6510161	17291	-0.449	-0.5673	Yes
136	TRAF6	4810292 6200132	17300	-0.454	-0.5591	Yes
137	AXIN2	3850131	17346	-0.482	-0.5523	Yes
138	MAP3K14	5890435	17378	-0.493	-0.5445	Yes
139	STAT2	3780519	17400	-0.501	-0.5361	Yes
140	ITGA6	3830129	17446	-0.521	-0.5285	Yes
141	AXL	1770095	17529	-0.559	-0.5223	Yes
142	RALBP1	4780632	17534	-0.560	-0.5117	Yes
143	PIK3CG	5890110	17542	-0.565	-0.5013	Yes
144	AXIN1	3360358 6940451	17576	-0.578	-0.4920	Yes
145	MAP2K6	1230056 2940204	17578	-0.578	-0.4810	Yes
146	VAV1	6020487	17649	-0.615	-0.4730	Yes
147	IL6ST	5890047	17666	-0.627	-0.4619	Yes
148	SH3BP2	610131	17694	-0.641	-0.4511	Yes
149	ITGAL	1450324	17702	-0.646	-0.4391	Yes
150	BCL10	2360397	17750	-0.680	-0.4286	Yes
151	GNB1	2120397	17751	-0.681	-0.4156	Yes
152	TNFRSF14	5050438	17754	-0.684	-0.4026	Yes
153	DGKQ	2480609	17917	-0.799	-0.3961	Yes
154	STAT3	460040 3710341	17921	-0.802	-0.3809	Yes
155	CRKL	4050427	17976	-0.847	-0.3676	Yes
156	STAT1	6510204 6590553	18002	-0.879	-0.3521	Yes
157	TRAF1	3440735	18060	-0.950	-0.3370	Yes
158	MAP3K3	610685	18205	-1.159	-0.3226	Yes
159	TRAF3	5690647	18242	-1.233	-0.3009	Yes
160	TIAM1	5420288	18338	-1.482	-0.2777	Yes
161	PDPK1	6650168	18363	-1.543	-0.2495	Yes
162	IFNGR1	610577	18371	-1.569	-0.2198	Yes
163	PTK2B	4730411	18381	-1.636	-0.1890	Yes
164	MAPK9	2060273 3780209 4070397	18415	-1.759	-0.1571	Yes
165	DGKG	1770025	18513	-2.400	-0.1164	Yes
166	DGKA	5720152 5890328	18531	-2.552	-0.0684	Yes
167	TNFRSF1A	1090390 6520735	18601	-3.812	0.0008	Yes