Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | REACTOME_SIGNALING_BY_GPCR |
Enrichment Score (ES) | -0.6952698 |
Normalized Enrichment Score (NES) | -1.7397975 |
Nominal p-value | 0.0 |
FDR q-value | 0.02165961 |
FWER p-Value | 0.019 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | F2 | 5720280 | 120 | 2.310 | 0.0637 | No | ||
2 | CNR2 | 2760398 | 1025 | 0.669 | 0.0351 | No | ||
3 | GAL | 3930279 | 1267 | 0.552 | 0.0388 | No | ||
4 | P2RY6 | 5290400 | 2062 | 0.293 | 0.0047 | No | ||
5 | P2RY10 | 6370039 6840204 | 2604 | 0.179 | -0.0191 | No | ||
6 | ROCK1 | 130044 | 2627 | 0.176 | -0.0150 | No | ||
7 | P2RY2 | 2640180 2810128 | 2908 | 0.138 | -0.0259 | No | ||
8 | GPR17 | 5890671 | 2917 | 0.137 | -0.0222 | No | ||
9 | CCL25 | 450541 540435 | 3226 | 0.109 | -0.0356 | No | ||
10 | ADCY6 | 450364 6290670 6940286 | 3240 | 0.107 | -0.0330 | No | ||
11 | HRH2 | 3840440 | 3242 | 0.107 | -0.0298 | No | ||
12 | SCTR | 2940070 | 3641 | 0.075 | -0.0491 | No | ||
13 | LTB4R | 1770056 | 3871 | 0.061 | -0.0596 | No | ||
14 | PDE4D | 2470528 6660014 | 3914 | 0.059 | -0.0601 | No | ||
15 | NTSR1 | 6510136 | 3984 | 0.055 | -0.0622 | No | ||
16 | PDYN | 5720408 | 3995 | 0.055 | -0.0611 | No | ||
17 | PNOC | 1990114 | 4226 | 0.045 | -0.0721 | No | ||
18 | OPN1SW | 6420377 | 4632 | 0.035 | -0.0930 | No | ||
19 | AVP | 2100113 | 4766 | 0.032 | -0.0992 | No | ||
20 | GRK5 | 1940348 4670053 | 4939 | 0.029 | -0.1077 | No | ||
21 | AVPR1A | 2120300 | 4965 | 0.028 | -0.1082 | No | ||
22 | ADCYAP1 | 520086 | 5025 | 0.027 | -0.1106 | No | ||
23 | GCG | 6220735 | 5145 | 0.025 | -0.1162 | No | ||
24 | ADRA1D | 380035 540025 | 5268 | 0.024 | -0.1221 | No | ||
25 | PTGER2 | 3170039 | 5317 | 0.023 | -0.1240 | No | ||
26 | PLCB2 | 360132 | 5394 | 0.022 | -0.1274 | No | ||
27 | IAPP | 4230040 | 5437 | 0.022 | -0.1290 | No | ||
28 | GNA14 | 3390017 | 5530 | 0.021 | -0.1334 | No | ||
29 | SSTR1 | 2630471 | 5654 | 0.019 | -0.1395 | No | ||
30 | KISS1 | 1580398 | 5854 | 0.017 | -0.1497 | No | ||
31 | GALR1 | 6020452 | 6040 | 0.016 | -0.1592 | No | ||
32 | MC2R | 2970504 | 6058 | 0.016 | -0.1597 | No | ||
33 | PTGER3 | 2900739 6770750 | 6115 | 0.015 | -0.1622 | No | ||
34 | CGB | 580273 | 6268 | 0.014 | -0.1700 | No | ||
35 | NTS | 380300 2120592 | 6294 | 0.014 | -0.1710 | No | ||
36 | IL8RB | 450592 1170537 | 6380 | 0.013 | -0.1752 | No | ||
37 | CASR | 610504 | 6413 | 0.013 | -0.1765 | No | ||
38 | TSHR | 1190687 5270364 | 6445 | 0.013 | -0.1778 | No | ||
39 | CCK | 6370368 | 6940 | 0.010 | -0.2042 | No | ||
40 | CCR3 | 50427 | 6950 | 0.010 | -0.2044 | No | ||
41 | CXCL11 | 1090551 | 6964 | 0.010 | -0.2048 | No | ||
42 | HCRTR2 | 2350463 | 7160 | 0.009 | -0.2151 | No | ||
43 | PIK3R1 | 4730671 | 7181 | 0.009 | -0.2159 | No | ||
44 | TACR3 | 4780017 | 7184 | 0.009 | -0.2157 | No | ||
45 | MTNR1A | 380204 | 7321 | 0.008 | -0.2228 | No | ||
46 | TACR2 | 1740358 | 7324 | 0.008 | -0.2227 | No | ||
47 | HTR1F | 670148 | 7334 | 0.008 | -0.2229 | No | ||
48 | LHCGR | 4560465 5860551 | 7394 | 0.008 | -0.2259 | No | ||
49 | DRD1 | 430025 | 7424 | 0.008 | -0.2272 | No | ||
50 | VIP | 2850647 | 7484 | 0.008 | -0.2302 | No | ||
51 | PPY | 2340373 | 7573 | 0.007 | -0.2347 | No | ||
52 | GLP2R | 4150577 5290273 7050095 | 7590 | 0.007 | -0.2354 | No | ||
53 | AKT1 | 5290746 | 7820 | 0.006 | -0.2476 | No | ||
54 | SST | 6590142 | 8056 | 0.005 | -0.2601 | No | ||
55 | HCRT | 2970463 | 8070 | 0.005 | -0.2607 | No | ||
56 | ADM2 | 4060102 | 8082 | 0.005 | -0.2611 | No | ||
57 | CCKBR | 2760128 | 8170 | 0.005 | -0.2657 | No | ||
58 | C5AR1 | 4540402 | 8239 | 0.005 | -0.2692 | No | ||
59 | GLP1R | 6420528 | 8327 | 0.004 | -0.2738 | No | ||
60 | EDNRA | 6900133 | 8329 | 0.004 | -0.2737 | No | ||
61 | GNAT1 | 5270048 6100170 | 8387 | 0.004 | -0.2766 | No | ||
62 | GRPR | 6020170 | 8433 | 0.004 | -0.2790 | No | ||
63 | ADRA2A | 5340520 | 8449 | 0.004 | -0.2797 | No | ||
64 | PPYR1 | 1410072 | 8555 | 0.004 | -0.2852 | No | ||
65 | VIPR2 | 6520050 | 8636 | 0.003 | -0.2895 | No | ||
66 | GNAZ | 6130296 | 8663 | 0.003 | -0.2908 | No | ||
67 | GPRC6A | 4560576 | 8765 | 0.003 | -0.2961 | No | ||
68 | GHRHR | 3130500 4010154 | 8915 | 0.002 | -0.3041 | No | ||
69 | PTGER1 | 6100132 | 9087 | 0.002 | -0.3133 | No | ||
70 | PTGFR | 3850373 | 9148 | 0.002 | -0.3165 | No | ||
71 | OXT | 3850692 | 9270 | 0.001 | -0.3230 | No | ||
72 | GHRH | 4570575 | 9363 | 0.001 | -0.3280 | No | ||
73 | BAI3 | 940692 | 9500 | 0.001 | -0.3353 | No | ||
74 | ADORA1 | 6370520 | 9664 | 0.000 | -0.3442 | No | ||
75 | GIP | 3170364 | 9670 | 0.000 | -0.3444 | No | ||
76 | EDN1 | 1770047 | 9775 | -0.000 | -0.3500 | No | ||
77 | PIK3CA | 6220129 | 9883 | -0.001 | -0.3558 | No | ||
78 | ADCYAP1R1 | 3390020 4280184 5360180 | 10113 | -0.001 | -0.3682 | No | ||
79 | HTR6 | 4850022 | 10202 | -0.002 | -0.3729 | No | ||
80 | P2RY4 | 630053 | 10522 | -0.002 | -0.3901 | No | ||
81 | CRH | 3710301 | 10535 | -0.003 | -0.3907 | No | ||
82 | HRH1 | 840100 | 10572 | -0.003 | -0.3925 | No | ||
83 | CALCA | 5860167 | 10672 | -0.003 | -0.3978 | No | ||
84 | CCR10 | 4050097 | 10815 | -0.003 | -0.4054 | No | ||
85 | GNGT1 | 5220156 | 11085 | -0.004 | -0.4198 | No | ||
86 | DARC | 3940050 | 11155 | -0.005 | -0.4234 | No | ||
87 | TACR1 | 70358 3840411 | 11250 | -0.005 | -0.4283 | No | ||
88 | IL8RA | 1580100 | 11340 | -0.005 | -0.4330 | No | ||
89 | CHRM5 | 5390333 | 11386 | -0.005 | -0.4353 | No | ||
90 | CHRM2 | 870750 | 11393 | -0.005 | -0.4354 | No | ||
91 | KNG1 | 6400576 6770347 | 11470 | -0.006 | -0.4394 | No | ||
92 | DRD3 | 4780402 | 11570 | -0.006 | -0.4445 | No | ||
93 | TAC1 | 7000195 380706 | 11607 | -0.006 | -0.4463 | No | ||
94 | GCGR | 6620497 | 11619 | -0.006 | -0.4467 | No | ||
95 | LHB | 1450368 | 11632 | -0.006 | -0.4472 | No | ||
96 | HCRTR1 | 1580273 | 11664 | -0.006 | -0.4486 | No | ||
97 | AGTR1 | 4780524 2680592 | 11668 | -0.006 | -0.4486 | No | ||
98 | CALCR | 1690494 | 12280 | -0.009 | -0.4814 | No | ||
99 | FSHR | 610041 7040121 | 12307 | -0.009 | -0.4825 | No | ||
100 | CGA | 630403 | 12431 | -0.010 | -0.4889 | No | ||
101 | CXCR6 | 3190440 | 12450 | -0.010 | -0.4896 | No | ||
102 | TSHB | 6770500 | 12745 | -0.012 | -0.5051 | No | ||
103 | XCR1 | 5080072 | 12826 | -0.012 | -0.5091 | No | ||
104 | PTGDR | 3850161 | 13087 | -0.014 | -0.5227 | No | ||
105 | FSHB | 7100592 | 13219 | -0.015 | -0.5293 | No | ||
106 | AGT | 7000575 | 13238 | -0.016 | -0.5298 | No | ||
107 | MC5R | 2640176 | 13500 | -0.018 | -0.5434 | No | ||
108 | NPFF | 2030280 | 13546 | -0.018 | -0.5453 | No | ||
109 | BDKRB1 | 730592 | 13903 | -0.024 | -0.5638 | No | ||
110 | OPRM1 | 5360279 | 13936 | -0.024 | -0.5648 | No | ||
111 | P2RY1 | 6040121 | 14107 | -0.027 | -0.5732 | No | ||
112 | CRHR2 | 4590672 | 14113 | -0.027 | -0.5727 | No | ||
113 | ADORA2A | 1990687 | 14116 | -0.027 | -0.5719 | No | ||
114 | CALCRL | 4280035 | 14331 | -0.032 | -0.5826 | No | ||
115 | CCR6 | 5720368 6020176 | 14337 | -0.032 | -0.5819 | No | ||
116 | GRM6 | 2030398 | 14350 | -0.032 | -0.5815 | No | ||
117 | CX3CL1 | 3990707 | 14503 | -0.035 | -0.5887 | No | ||
118 | GNAQ | 430670 4210131 5900736 | 14645 | -0.040 | -0.5951 | No | ||
119 | AVPR2 | 360064 | 14915 | -0.051 | -0.6081 | No | ||
120 | GNA12 | 1230301 | 15101 | -0.060 | -0.6163 | No | ||
121 | HTR2A | 360037 6330255 | 15199 | -0.067 | -0.6196 | No | ||
122 | SCT | 2230348 | 15392 | -0.079 | -0.6275 | No | ||
123 | P2RY14 | 6100497 | 16077 | -0.158 | -0.6598 | No | ||
124 | GNA13 | 4590102 | 16639 | -0.254 | -0.6824 | Yes | ||
125 | NMB | 3360735 | 16697 | -0.265 | -0.6774 | Yes | ||
126 | ADRBK1 | 1340333 | 16790 | -0.283 | -0.6738 | Yes | ||
127 | PTGIR | 2100563 | 16902 | -0.313 | -0.6703 | Yes | ||
128 | RHOG | 6760575 | 17364 | -0.489 | -0.6804 | Yes | ||
129 | RAMP1 | 2320168 | 17482 | -0.534 | -0.6705 | Yes | ||
130 | GNG2 | 2230390 | 17510 | -0.549 | -0.6553 | Yes | ||
131 | PIK3CG | 5890110 | 17542 | -0.565 | -0.6398 | Yes | ||
132 | GNB1 | 2120397 | 17751 | -0.681 | -0.6304 | Yes | ||
133 | ADRB2 | 3290373 | 17896 | -0.784 | -0.6144 | Yes | ||
134 | F2R | 4810180 | 18172 | -1.096 | -0.5960 | Yes | ||
135 | PDPK1 | 6650168 | 18363 | -1.543 | -0.5594 | Yes | ||
136 | GNAS | 630441 1850373 4050152 | 18468 | -2.029 | -0.5034 | Yes | ||
137 | TBXA2R | 2370292 3940066 | 18517 | -2.443 | -0.4318 | Yes | ||
138 | CCL5 | 3710397 | 18554 | -2.751 | -0.3502 | Yes | ||
139 | XCL1 | 3800504 | 18560 | -2.844 | -0.2641 | Yes | ||
140 | CCR7 | 2060687 | 18568 | -3.010 | -0.1731 | Yes | ||
141 | RHOA | 580142 5900131 5340450 | 18614 | -5.784 | 0.0001 | Yes |