Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS |
Enrichment Score (ES) | -0.5767473 |
Normalized Enrichment Score (NES) | -1.575625 |
Nominal p-value | 0.0 |
FDR q-value | 0.22760874 |
FWER p-Value | 0.977 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EGR1 | 4610347 | 214 | 1.010 | 0.0123 | No | ||
2 | TNK2 | 1570390 | 429 | 0.692 | 0.0171 | No | ||
3 | ERCC2 | 2360750 4060390 6550138 | 470 | 0.657 | 0.0305 | No | ||
4 | SMAD3 | 6450671 | 532 | 0.607 | 0.0416 | No | ||
5 | TNFSF13 | 2650170 | 776 | 0.479 | 0.0398 | No | ||
6 | STUB1 | 5860086 | 983 | 0.408 | 0.0383 | No | ||
7 | ARF6 | 3520026 | 994 | 0.404 | 0.0473 | No | ||
8 | SQSTM1 | 6550056 | 1025 | 0.393 | 0.0550 | No | ||
9 | BMP7 | 870039 | 1090 | 0.375 | 0.0604 | No | ||
10 | HMGA1 | 6580408 | 1226 | 0.349 | 0.0614 | No | ||
11 | SCAP | 3800706 | 1230 | 0.349 | 0.0695 | No | ||
12 | SMARCD1 | 3060193 3850184 6400369 | 1240 | 0.347 | 0.0772 | No | ||
13 | SUPT4H1 | 6200056 | 1313 | 0.332 | 0.0812 | No | ||
14 | RBM14 | 5340731 5690315 | 1486 | 0.297 | 0.0789 | No | ||
15 | LTB | 3990672 | 1536 | 0.288 | 0.0830 | No | ||
16 | MRPL12 | 3120112 | 1636 | 0.270 | 0.0841 | No | ||
17 | NUP62 | 1240128 | 1640 | 0.269 | 0.0903 | No | ||
18 | CD80 | 870112 | 1715 | 0.259 | 0.0924 | No | ||
19 | EIF5A | 1500059 5290022 6370026 | 1749 | 0.254 | 0.0966 | No | ||
20 | TNFRSF8 | 870136 4810446 | 1850 | 0.237 | 0.0968 | No | ||
21 | SPN | 3520338 3870671 | 1940 | 0.223 | 0.0973 | No | ||
22 | PPP2R4 | 670280 2900097 | 2021 | 0.213 | 0.0980 | No | ||
23 | EPC1 | 1570050 5290095 6900193 | 2078 | 0.205 | 0.0998 | No | ||
24 | EBI3 | 5340300 | 2154 | 0.195 | 0.1004 | No | ||
25 | MYST3 | 5270500 | 2270 | 0.181 | 0.0984 | No | ||
26 | TRIM28 | 380292 | 2399 | 0.165 | 0.0954 | No | ||
27 | TGFB1 | 1940162 | 2566 | 0.146 | 0.0899 | No | ||
28 | SUPT5H | 4150546 | 2670 | 0.135 | 0.0875 | No | ||
29 | SPI1 | 1410397 | 2778 | 0.125 | 0.0847 | No | ||
30 | MYST1 | 2190397 | 2865 | 0.117 | 0.0828 | No | ||
31 | BOLL | 6100743 | 3227 | 0.092 | 0.0654 | No | ||
32 | EPAS1 | 5290156 | 3250 | 0.090 | 0.0663 | No | ||
33 | DYRK1B | 5860706 | 3519 | 0.076 | 0.0536 | No | ||
34 | TP53 | 6130707 | 3540 | 0.075 | 0.0543 | No | ||
35 | TLR4 | 1690167 2650369 3850333 | 3585 | 0.073 | 0.0536 | No | ||
36 | CAMKK2 | 5270047 | 3860 | 0.062 | 0.0402 | No | ||
37 | SMARCD3 | 4070497 | 3998 | 0.058 | 0.0342 | No | ||
38 | GAPDHS | 2690463 | 4118 | 0.054 | 0.0290 | No | ||
39 | HNF4A | 6620440 | 4142 | 0.053 | 0.0290 | No | ||
40 | ELL3 | 1770484 | 4241 | 0.050 | 0.0248 | No | ||
41 | EGFR | 4920138 6480521 | 4355 | 0.047 | 0.0198 | No | ||
42 | HSP90AA1 | 4560041 5220133 2120722 | 4376 | 0.046 | 0.0198 | No | ||
43 | GLI2 | 3060632 | 4406 | 0.046 | 0.0193 | No | ||
44 | FOXP3 | 940707 1850692 | 4525 | 0.043 | 0.0140 | No | ||
45 | CDC42EP2 | 540079 2970138 | 4537 | 0.043 | 0.0144 | No | ||
46 | PLAGL1 | 3190082 6200193 | 4597 | 0.041 | 0.0122 | No | ||
47 | ACVR1 | 6840671 | 4738 | 0.039 | 0.0055 | No | ||
48 | CLCF1 | 4920176 6550750 | 4773 | 0.038 | 0.0045 | No | ||
49 | FOXO3 | 2510484 4480451 | 4783 | 0.038 | 0.0050 | No | ||
50 | THRAP3 | 6180309 | 4835 | 0.037 | 0.0031 | No | ||
51 | CITED2 | 5670114 5130088 | 4868 | 0.036 | 0.0022 | No | ||
52 | ATG7 | 3940619 | 4932 | 0.035 | -0.0004 | No | ||
53 | MAP2K3 | 5570193 | 5082 | 0.032 | -0.0077 | No | ||
54 | FOXE1 | 4810164 | 5098 | 0.032 | -0.0078 | No | ||
55 | UBE2N | 520369 2900047 | 5562 | 0.026 | -0.0323 | No | ||
56 | CREB5 | 2320368 | 5656 | 0.024 | -0.0367 | No | ||
57 | EIF2B5 | 430315 6900400 | 5773 | 0.023 | -0.0425 | No | ||
58 | UTF1 | 5700593 | 5824 | 0.023 | -0.0447 | No | ||
59 | CARD14 | 1770369 5550605 | 5842 | 0.022 | -0.0450 | No | ||
60 | IL4 | 6020537 | 6057 | 0.020 | -0.0562 | No | ||
61 | ACVRL1 | 3290600 | 6155 | 0.019 | -0.0610 | No | ||
62 | GLIS2 | 4150471 4810170 | 6309 | 0.018 | -0.0688 | No | ||
63 | TBX5 | 2900132 6370484 | 6316 | 0.018 | -0.0687 | No | ||
64 | NUFIP1 | 6350241 | 6390 | 0.017 | -0.0723 | No | ||
65 | BRCA1 | 4780669 | 6679 | 0.015 | -0.0875 | No | ||
66 | APOA2 | 6510364 6860411 | 7045 | 0.013 | -0.1070 | No | ||
67 | IL31RA | 6770541 | 7198 | 0.012 | -0.1150 | No | ||
68 | IL27 | 1990324 | 7750 | 0.009 | -0.1447 | No | ||
69 | CDK7 | 2640451 | 7752 | 0.009 | -0.1445 | No | ||
70 | NPAS2 | 770670 | 7804 | 0.009 | -0.1470 | No | ||
71 | RORB | 6400035 | 7857 | 0.009 | -0.1496 | No | ||
72 | MKL2 | 5700204 | 8056 | 0.008 | -0.1602 | No | ||
73 | GCK | 2370273 | 8063 | 0.008 | -0.1603 | No | ||
74 | NRIP1 | 3190039 | 8083 | 0.008 | -0.1612 | No | ||
75 | FOXF2 | 1240091 | 8114 | 0.008 | -0.1626 | No | ||
76 | DEFB103A | 50014 | 8187 | 0.008 | -0.1663 | No | ||
77 | ELA2 | 1570452 5270129 | 8228 | 0.008 | -0.1683 | No | ||
78 | IL3 | 2480280 | 8334 | 0.007 | -0.1738 | No | ||
79 | GATA4 | 1410215 2690609 | 8594 | 0.006 | -0.1877 | No | ||
80 | ABCA1 | 6290156 | 8669 | 0.006 | -0.1916 | No | ||
81 | NCK1 | 6200575 6510050 | 8787 | 0.006 | -0.1978 | No | ||
82 | HIF1A | 5670605 | 8842 | 0.005 | -0.2006 | No | ||
83 | IL9 | 3440338 | 9272 | 0.004 | -0.2238 | No | ||
84 | TLR1 | 1410524 | 9780 | 0.003 | -0.2512 | No | ||
85 | GLMN | 5290563 5890239 | 9841 | 0.002 | -0.2544 | No | ||
86 | TLR9 | 670093 670706 | 9889 | 0.002 | -0.2569 | No | ||
87 | CCND2 | 5340167 | 9902 | 0.002 | -0.2575 | No | ||
88 | ESRRG | 4010181 | 9935 | 0.002 | -0.2592 | No | ||
89 | EHF | 4560088 | 9976 | 0.002 | -0.2613 | No | ||
90 | IRF4 | 610133 | 10272 | 0.001 | -0.2773 | No | ||
91 | PPARA | 2060026 | 10473 | 0.001 | -0.2881 | No | ||
92 | SMARCA1 | 4230315 | 10479 | 0.001 | -0.2884 | No | ||
93 | EREG | 50519 4920129 | 10683 | 0.000 | -0.2994 | No | ||
94 | DAZL | 4050082 | 10933 | -0.001 | -0.3129 | No | ||
95 | IL12B | 460008 | 11040 | -0.001 | -0.3186 | No | ||
96 | ARNT2 | 1740594 | 11133 | -0.001 | -0.3236 | No | ||
97 | UBE2D1 | 1850400 | 11163 | -0.001 | -0.3251 | No | ||
98 | BMP6 | 2100128 | 11286 | -0.002 | -0.3317 | No | ||
99 | NCOA6 | 1780333 6450110 | 11459 | -0.002 | -0.3410 | No | ||
100 | IL20 | 4850647 | 11533 | -0.002 | -0.3449 | No | ||
101 | TLR6 | 510102 3390148 | 11608 | -0.003 | -0.3488 | No | ||
102 | MYST4 | 1400563 2570687 3360458 6840402 | 11916 | -0.004 | -0.3654 | No | ||
103 | GLI1 | 4560176 | 11972 | -0.004 | -0.3683 | No | ||
104 | FOXD3 | 6550156 | 12005 | -0.004 | -0.3699 | No | ||
105 | TLR8 | 1240092 | 12054 | -0.004 | -0.3724 | No | ||
106 | FOXH1 | 2060180 | 12354 | -0.005 | -0.3885 | No | ||
107 | RGMB | 670504 4570450 | 12529 | -0.006 | -0.3978 | No | ||
108 | TLR3 | 6760451 | 12565 | -0.006 | -0.3996 | No | ||
109 | BMP4 | 380113 | 12597 | -0.006 | -0.4011 | No | ||
110 | SAMD4A | 1170717 | 12794 | -0.007 | -0.4116 | No | ||
111 | YWHAH | 1660133 2810053 | 12889 | -0.008 | -0.4165 | No | ||
112 | LYN | 6040600 | 12993 | -0.008 | -0.4219 | No | ||
113 | IL6 | 380133 | 13300 | -0.010 | -0.4382 | No | ||
114 | PRG3 | 6220020 | 13616 | -0.013 | -0.4550 | No | ||
115 | PAX8 | 5050301 5290164 | 13741 | -0.014 | -0.4614 | No | ||
116 | PPARGC1A | 4670040 | 13963 | -0.016 | -0.4730 | No | ||
117 | BPTF | 940541 4540152 | 14159 | -0.019 | -0.4831 | No | ||
118 | TDGF1 | 1690338 6760070 | 14253 | -0.020 | -0.4877 | No | ||
119 | CLOCK | 1410070 2940292 3390075 | 14298 | -0.021 | -0.4896 | No | ||
120 | NFATC2 | 70450 540097 | 14309 | -0.021 | -0.4897 | No | ||
121 | CDC42EP5 | 6400397 | 14397 | -0.022 | -0.4938 | No | ||
122 | RXRA | 3800471 | 14505 | -0.024 | -0.4991 | No | ||
123 | TLR7 | 3140300 | 14653 | -0.027 | -0.5064 | No | ||
124 | TCF3 | 5080022 | 14733 | -0.029 | -0.5100 | No | ||
125 | NOTCH4 | 2450040 6370707 | 14957 | -0.035 | -0.5213 | No | ||
126 | RAD51 | 6110450 6980280 | 15032 | -0.039 | -0.5243 | No | ||
127 | GLIS1 | 840471 | 15182 | -0.045 | -0.5314 | No | ||
128 | UBB | 4810138 | 15183 | -0.045 | -0.5303 | No | ||
129 | CD81 | 5270093 | 15350 | -0.051 | -0.5381 | No | ||
130 | ELF4 | 4850193 | 15444 | -0.057 | -0.5418 | No | ||
131 | HIVEP3 | 3990551 | 15632 | -0.069 | -0.5503 | No | ||
132 | NARG1 | 5910563 6350095 | 15804 | -0.081 | -0.5577 | No | ||
133 | BCL10 | 2360397 | 15829 | -0.083 | -0.5570 | No | ||
134 | TRERF1 | 6370017 6940138 | 15841 | -0.084 | -0.5556 | No | ||
135 | EGF | 5220154 | 15914 | -0.089 | -0.5574 | No | ||
136 | ERCC3 | 6900008 | 15992 | -0.095 | -0.5593 | No | ||
137 | MAPT | 360706 1230706 | 16010 | -0.097 | -0.5579 | No | ||
138 | IL12A | 7100551 | 16072 | -0.102 | -0.5588 | No | ||
139 | NSD1 | 4560519 4780672 | 16074 | -0.102 | -0.5565 | No | ||
140 | YAF2 | 940053 | 16441 | -0.141 | -0.5730 | No | ||
141 | PPARGC1B | 3290114 | 16512 | -0.152 | -0.5732 | Yes | ||
142 | HSP90AB1 | 3170358 5390102 6040093 | 16561 | -0.159 | -0.5720 | Yes | ||
143 | AKTIP | 6350575 | 16575 | -0.162 | -0.5689 | Yes | ||
144 | MYO6 | 2190332 | 16625 | -0.169 | -0.5675 | Yes | ||
145 | CD28 | 1400739 4210093 | 16693 | -0.179 | -0.5669 | Yes | ||
146 | BCL3 | 3990440 | 16752 | -0.187 | -0.5656 | Yes | ||
147 | MED6 | 6840500 | 16755 | -0.187 | -0.5613 | Yes | ||
148 | SP1 | 6590017 | 16838 | -0.205 | -0.5609 | Yes | ||
149 | NCK2 | 2510010 | 16852 | -0.206 | -0.5567 | Yes | ||
150 | ARNTL | 3170463 | 16863 | -0.209 | -0.5523 | Yes | ||
151 | PHF5A | 2690519 | 16977 | -0.228 | -0.5530 | Yes | ||
152 | TPP1 | 3990446 | 16979 | -0.228 | -0.5477 | Yes | ||
153 | HCLS1 | 7100309 | 17030 | -0.237 | -0.5447 | Yes | ||
154 | TNFRSF1A | 1090390 6520735 | 17180 | -0.268 | -0.5465 | Yes | ||
155 | ILF2 | 2900253 | 17184 | -0.270 | -0.5402 | Yes | ||
156 | SMAD2 | 4200592 | 17271 | -0.295 | -0.5379 | Yes | ||
157 | MNAT1 | 730292 2350364 | 17289 | -0.300 | -0.5317 | Yes | ||
158 | CREBBP | 5690035 7040050 | 17381 | -0.327 | -0.5289 | Yes | ||
159 | TCF4 | 520021 | 17388 | -0.328 | -0.5215 | Yes | ||
160 | HNRPAB | 540504 | 17390 | -0.328 | -0.5138 | Yes | ||
161 | MAML1 | 2760008 | 17520 | -0.360 | -0.5122 | Yes | ||
162 | GTF2H1 | 2570746 2650148 | 17587 | -0.381 | -0.5068 | Yes | ||
163 | CCND3 | 380528 730500 | 17704 | -0.426 | -0.5029 | Yes | ||
164 | MED12 | 4920095 | 17715 | -0.430 | -0.4933 | Yes | ||
165 | RSF1 | 1580097 | 17746 | -0.443 | -0.4844 | Yes | ||
166 | RUNX1 | 3840711 | 18014 | -0.563 | -0.4855 | Yes | ||
167 | ARHGEF11 | 1780288 | 18092 | -0.610 | -0.4752 | Yes | ||
168 | ARPP-19 | 5700025 | 18169 | -0.654 | -0.4639 | Yes | ||
169 | CCNH | 3190347 | 18256 | -0.727 | -0.4513 | Yes | ||
170 | ATF7IP | 2690176 6770021 | 18287 | -0.759 | -0.4349 | Yes | ||
171 | SMARCC1 | 5080019 7100047 | 18369 | -0.848 | -0.4192 | Yes | ||
172 | HPRT1 | 1690398 4920619 6350170 | 18388 | -0.871 | -0.3996 | Yes | ||
173 | XRCC6 | 2850450 3870528 | 18427 | -0.927 | -0.3796 | Yes | ||
174 | CTCF | 5340017 | 18434 | -0.936 | -0.3578 | Yes | ||
175 | ELF1 | 4780450 | 18546 | -1.372 | -0.3313 | Yes | ||
176 | IL5 | 6370364 1050193 | 18579 | -1.714 | -0.2924 | Yes | ||
177 | CCND1 | 460524 770309 3120576 6980398 | 18589 | -1.801 | -0.2502 | Yes | ||
178 | ILF3 | 940722 3190647 6520110 | 18599 | -2.087 | -0.2012 | Yes | ||
179 | ATF4 | 730441 1740195 | 18600 | -2.197 | -0.1492 | Yes | ||
180 | ARID1A | 2630022 1690551 4810110 | 18616 | -6.327 | 0.0000 | Yes |