Details for gene set NUCLEOPLASM[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	NUCLEOPLASM
Enrichment Score (ES)	-0.57001096
Normalized Enrichment Score (NES)	-1.5787143
Nominal p-value	0.0
FDR q-value	0.24189898
FWER p-Value	0.971

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SFRS2	50707 380593	7	4.052	0.0721	No
2	HES6	540411 6550504	96	1.504	0.0942	No
3	HDAC5	2370035 6370139	355	0.797	0.0945	No
4	TAF6	2470541 4280497	458	0.665	0.1008	No
5	ERCC2	2360750 4060390 6550138	470	0.657	0.1120	No
6	MCRS1	110121 2340592 5270484	732	0.496	0.1067	No
7	SMARCB1	5860494	813	0.463	0.1106	No
8	GEMIN7	2320433	821	0.460	0.1185	No
9	TAF10	2760020	1067	0.380	0.1120	No
10	HMGA1	6580408	1226	0.349	0.1096	No
11	SMARCD1	3060193 3850184 6400369	1240	0.347	0.1151	No
12	NUP98	2850465	1247	0.346	0.1210	No
13	PMF1	5130273	1421	0.310	0.1172	No
14	HTATIP	5360739	1453	0.303	0.1209	No
15	RBM14	5340731 5690315	1486	0.297	0.1245	No
16	HDAC7A	2570278	1494	0.296	0.1294	No
17	EPC1	1570050 5290095 6900193	2078	0.205	0.1014	No
18	MEN1	4850300 5900671	2092	0.203	0.1043	No
19	RUVBL2	1190377	2141	0.197	0.1052	No
20	ISG20	1770750	2214	0.188	0.1047	No
21	HDAC6	6200446	2379	0.166	0.0988	No
22	TOP1	770471 4060632 6650324	2420	0.162	0.0995	No
23	HDAC3	4060072	2427	0.161	0.1020	No
24	MPG	2760021	2586	0.144	0.0960	No
25	TAF6L	1850056	2588	0.144	0.0986	No
26	TIMM50	1500139	2595	0.143	0.1008	No
27	ZBTB16	3290022	2803	0.123	0.0918	No
28	APTX	3360041 4560167	2823	0.121	0.0929	No
29	NUDT21	1240167	2870	0.117	0.0925	No
30	U2AF1	5130292	3081	0.102	0.0829	No
31	TAF12	3710746 4920300 6180603	3221	0.092	0.0770	No
32	EPAS1	5290156	3250	0.090	0.0771	No
33	TAF9	1850458 3830136	3436	0.080	0.0685	No
34	TFIP11	1340301	3445	0.079	0.0695	No
35	CHEK2	610139 1050022	3468	0.079	0.0697	No
36	NDUFA13	6220021	3475	0.078	0.0708	No
37	TP53	6130707	3540	0.075	0.0686	No
38	ACTB	1660736 2030204 2060215 5050047	3579	0.073	0.0679	No
39	HDAC10	2850204	3594	0.072	0.0684	No
40	POLR2J	7100372	3699	0.068	0.0640	No
41	ATXN1	5550156	3707	0.068	0.0648	No
42	CDK8	1050113 1190601 1780358 6110102	3747	0.066	0.0639	No
43	CHAF1B	3940142	3771	0.066	0.0638	No
44	CIB1	7100722	3890	0.061	0.0585	No
45	SMARCD3	4070497	3998	0.058	0.0537	No
46	CHAF1A	6040647	4123	0.054	0.0479	No
47	INTS6	6040736 7570767	4392	0.046	0.0342	No
48	NKX2-5	5390438	4396	0.046	0.0349	No
49	LMO4	3800746	4468	0.045	0.0318	No
50	TAF7	6400504 6660601	4636	0.040	0.0235	No
51	FOXE3	6900102	4686	0.040	0.0215	No
52	THRAP3	6180309	4835	0.037	0.0142	No
53	WRN	540687 1240093	4960	0.035	0.0080	No
54	GCM1	6510687	5170	0.031	-0.0027	No
55	LRCH4	5220279 6510026	5192	0.031	-0.0033	No
56	OGG1	1940279	5739	0.024	-0.0326	No
57	RUVBL1	4280239 5080273	5754	0.023	-0.0329	No
58	POLR3C	6940546	5819	0.023	-0.0360	No
59	HIPK2	6350647	5989	0.021	-0.0448	No
60	GLIS2	4150471 4810170	6309	0.018	-0.0618	No
61	NUFIP1	6350241	6390	0.017	-0.0658	No
62	NAP1L3	6020079	6496	0.016	-0.0712	No
63	POLR3K	1400577 5290500	6625	0.016	-0.0779	No
64	PPP1R9B	3130619	6884	0.014	-0.0916	No
65	CBX1	5080408 1980239	6946	0.013	-0.0947	No
66	SPTBN4	4150279 5270286	6979	0.013	-0.0962	No
67	IFI16	6520601	7254	0.012	-0.1109	No
68	FMR1	5050075	7468	0.011	-0.1222	No
69	SMARCD2	3830619	7662	0.010	-0.1326	No
70	NPAS2	770670	7804	0.009	-0.1400	No
71	POLR2B	3780138	7960	0.009	-0.1483	No
72	PRM2	3060368	8100	0.008	-0.1557	No
73	FOXF2	1240091	8114	0.008	-0.1563	No
74	FIGLA	4780458	8119	0.008	-0.1563	No
75	BNIP3	3140270	8305	0.007	-0.1663	No
76	POLR2A	5220647	8436	0.007	-0.1732	No
77	HDAC9	1990010 2260133	8603	0.006	-0.1821	No
78	HIF1A	5670605	8842	0.005	-0.1949	No
79	GEMIN6	2120288 3830176	9105	0.005	-0.2091	No
80	POLA1	4760541	9613	0.003	-0.2365	No
81	PHB	2260739	9622	0.003	-0.2369	No
82	NCR1	2450026	10063	0.002	-0.2608	No
83	TAF5	3450288 5890193 6860435	10196	0.001	-0.2679	No
84	ELL2	6420091	10575	0.000	-0.2884	No
85	ELP4	1230576	10689	0.000	-0.2946	No
86	XPO1	540707	10862	-0.000	-0.3039	No
87	SP100	3440632	11122	-0.001	-0.3179	No
88	PITX2	870537 2690139	11222	-0.001	-0.3233	No
89	TAF4	1450170	11457	-0.002	-0.3360	No
90	NCOA6	1780333 6450110	11459	-0.002	-0.3360	No
91	TDG	2900358 2940079	11705	-0.003	-0.3492	No
92	NAP1L2	130047	12094	-0.004	-0.3702	No
93	CPSF3	2480671	12499	-0.006	-0.3920	No
94	IKBKAP	1740746 3120364	12698	-0.007	-0.4027	No
95	UBE2I	2680056 6350446	12940	-0.008	-0.4156	No
96	NFYC	1400746	12942	-0.008	-0.4155	No
97	RTCD1	7000041	13040	-0.009	-0.4206	No
98	PRPF31	6100360	13334	-0.010	-0.4364	No
99	PTF1A	6450377	13733	-0.014	-0.4577	No
100	PAX8	5050301 5290164	13741	-0.014	-0.4579	No
101	PML	50093 2190435 2450402 3840082	13951	-0.016	-0.4689	No
102	PPARGC1A	4670040	13963	-0.016	-0.4692	No
103	GEMIN5	3120577	14004	-0.017	-0.4711	No
104	ATXN3	50156 2900095	14227	-0.020	-0.4828	No
105	CLOCK	1410070 2940292 3390075	14298	-0.021	-0.4862	No
106	NR6A1	4010347	14357	-0.022	-0.4890	No
107	PHF21A	610014	14450	-0.023	-0.4936	No
108	RELA	3830075	14477	-0.024	-0.4946	No
109	TOPBP1	6020333	14491	-0.024	-0.4948	No
110	HDAC8	3440504	14532	-0.025	-0.4966	No
111	ARID4A	520156 1050707	14810	-0.031	-0.5111	No
112	ERCC5	770025 4540692	14813	-0.032	-0.5106	No
113	SAP18	3610092	15068	-0.040	-0.5237	No
114	WDR4	610390 1850368 3800338 4780463	15144	-0.043	-0.5270	No
115	HDAC11	2510242	15228	-0.046	-0.5307	No
116	GTF2F1	360093	15334	-0.051	-0.5354	No
117	PTBP1	4070736	15409	-0.055	-0.5385	No
118	ELF4	4850193	15444	-0.057	-0.5393	No
119	PHF12	870400 3130687	15495	-0.060	-0.5410	No
120	RBBP5	2760735 6760164	15562	-0.065	-0.5434	No
121	MDM2	3450053 5080138	15571	-0.065	-0.5427	No
122	POLQ	1050053 2190102	15615	-0.067	-0.5438	No
123	SMARCA5	6620050	15678	-0.072	-0.5459	No
124	DYRK1A	3190181	15694	-0.073	-0.5454	No
125	COIL	4480408	15737	-0.076	-0.5463	No
126	POLI	4280215	15767	-0.079	-0.5465	No
127	NARG1	5910563 6350095	15804	-0.081	-0.5470	No
128	NUP54	940546 2360156 4060278	15832	-0.084	-0.5469	No
129	POLR3H	1980369 6400348	15900	-0.088	-0.5490	No
130	GTF3C3	2450066	15959	-0.093	-0.5505	No
131	ERCC3	6900008	15992	-0.095	-0.5505	No
132	MCM7	3290292 5220056	16086	-0.103	-0.5537	No
133	FUSIP1	520082 5390114	16103	-0.105	-0.5527	No
134	TOP2B	6980309	16219	-0.116	-0.5569	No
135	CDK9	630707	16333	-0.128	-0.5607	No
136	GTF3C5	4540280 4540309	16505	-0.151	-0.5673	Yes
137	PPARGC1B	3290114	16512	-0.152	-0.5649	Yes
138	ASF1A	7050020	16589	-0.163	-0.5661	Yes
139	NAP1L1	2510593 5900215 5090470 450079 4920280	16594	-0.164	-0.5634	Yes
140	POLR2E	2900348 3360348	16620	-0.169	-0.5618	Yes
141	MYO6	2190332	16625	-0.169	-0.5589	Yes
142	GTF2H4	3520100	16704	-0.180	-0.5600	Yes
143	SHFM1	1570114	16705	-0.180	-0.5567	Yes
144	SMARCE1	4920465 4390398	16743	-0.186	-0.5554	Yes
145	MED6	6840500	16755	-0.187	-0.5527	Yes
146	EZH2	6130605 6380524	16764	-0.189	-0.5497	Yes
147	ARNTL	3170463	16863	-0.209	-0.5513	Yes
148	NFYA	5860368	16987	-0.229	-0.5539	Yes
149	TAF11	5720538	17002	-0.232	-0.5505	Yes
150	CPSF1	6290064	17013	-0.233	-0.5469	Yes
151	ING2	4850497	17027	-0.237	-0.5433	Yes
152	HCLS1	7100309	17030	-0.237	-0.5392	Yes
153	YEATS4	3130242	17042	-0.240	-0.5355	Yes
154	HDAC1	2850670	17220	-0.280	-0.5401	Yes
155	ASH2L	580152	17269	-0.295	-0.5374	Yes
156	SMAD2	4200592	17271	-0.295	-0.5322	Yes
157	ZNF148	6420403	17296	-0.302	-0.5281	Yes
158	TAF13	4050692	17339	-0.316	-0.5247	Yes
159	GIT2	6040039 6770181	17367	-0.323	-0.5204	Yes
160	OIP5	3120500 4780537	17375	-0.324	-0.5150	Yes
161	GTF3C1	1990368 4210037	17444	-0.342	-0.5126	Yes
162	MPHOSPH1	4610427	17479	-0.351	-0.5081	Yes
163	NAP1L4	1240504	17495	-0.354	-0.5026	Yes
164	MED4	4480050	17547	-0.369	-0.4988	Yes
165	SNAPC4	2190184	17553	-0.371	-0.4924	Yes
166	SMARCA4	6980528	17558	-0.371	-0.4860	Yes
167	MKI67IP	3060132	17577	-0.379	-0.4802	Yes
168	GTF2H1	2570746 2650148	17587	-0.381	-0.4739	Yes
169	RB1	5900338	17613	-0.394	-0.4682	Yes
170	GTF3C2	670494	17641	-0.406	-0.4624	Yes
171	POLH	2690528	17651	-0.409	-0.4555	Yes
172	RPA1	360452	17708	-0.427	-0.4509	Yes
173	MED12	4920095	17715	-0.430	-0.4436	Yes
174	GTF3C4	1940750 4730114	17717	-0.432	-0.4359	Yes
175	RSF1	1580097	17746	-0.443	-0.4295	Yes
176	RBM39	4230458 6450280	17786	-0.458	-0.4234	Yes
177	ELP3	3440438	17802	-0.467	-0.4159	Yes
178	MRE11A	3850601 4670332	17933	-0.523	-0.4136	Yes
179	TOPORS	4060592	17954	-0.535	-0.4051	Yes
180	KPNA2	3450114	17970	-0.540	-0.3962	Yes
181	NFYB	1850053	17987	-0.548	-0.3873	Yes
182	WDHD1	3450390	17996	-0.555	-0.3778	Yes
183	SAP30	5080735	18044	-0.582	-0.3699	Yes
184	IVNS1ABP	4760601 6520113	18081	-0.605	-0.3611	Yes
185	TRIM27	3710575 4780112	18125	-0.628	-0.3522	Yes
186	ZNF638	6510112	18145	-0.641	-0.3417	Yes
187	SMAD4	5670519	18179	-0.658	-0.3318	Yes
188	EED	2320373	18198	-0.671	-0.3207	Yes
189	SFRS2IP	730687 1500373	18233	-0.700	-0.3100	Yes
190	TOP2A	360717	18276	-0.748	-0.2989	Yes
191	SMARCC1	5080019 7100047	18369	-0.848	-0.2888	Yes
192	TBP	1450601 2810193	18389	-0.872	-0.2742	Yes
193	XRCC6	2850450 3870528	18427	-0.927	-0.2596	Yes
194	HDAC2	4050433	18455	-0.999	-0.2432	Yes
195	HNRPK	1190348 2060411 2570092 6840551	18560	-1.549	-0.2211	Yes
196	ACTL6A	5220543 6290541 2450093 4590332 5270722	18570	-1.652	-0.1921	Yes
197	EDF1	1660035 2640161	18572	-1.656	-0.1625	Yes
198	CDKN2A	4670215 4760047	18612	-2.884	-0.1130	Yes
199	ARID1A	2630022 1690551 4810110	18616	-6.327	-0.0000	Yes