Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$SREBP1_Q6 |
Enrichment Score (ES) | 0.5516917 |
Normalized Enrichment Score (NES) | 1.4278002 |
Nominal p-value | 0.007849294 |
FDR q-value | 0.62933373 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RHOA | 580142 5900131 5340450 | 11 | 3.476 | 0.0869 | Yes | ||
2 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.1590 | Yes | ||
3 | ETV5 | 110017 | 54 | 1.975 | 0.2069 | Yes | ||
4 | CORO1A | 3140609 3190020 3190037 | 68 | 1.660 | 0.2479 | Yes | ||
5 | DNMT3B | 2320138 4070059 | 94 | 1.518 | 0.2848 | Yes | ||
6 | DTX1 | 5900372 | 102 | 1.475 | 0.3216 | Yes | ||
7 | NDRG2 | 450403 | 104 | 1.446 | 0.3579 | Yes | ||
8 | PDXP | 5050204 460273 6040102 | 146 | 1.176 | 0.3853 | Yes | ||
9 | IMMT | 870450 4280438 | 164 | 1.111 | 0.4123 | Yes | ||
10 | SSBP2 | 2260725 2900400 4730711 | 220 | 1.002 | 0.4346 | Yes | ||
11 | DLK1 | 1240138 | 235 | 0.977 | 0.4584 | Yes | ||
12 | HSPG2 | 2510687 6220750 | 453 | 0.669 | 0.4635 | Yes | ||
13 | FXC1 | 3710053 4060575 | 573 | 0.580 | 0.4716 | Yes | ||
14 | PTK2B | 4730411 | 591 | 0.567 | 0.4850 | Yes | ||
15 | RHOG | 6760575 | 684 | 0.516 | 0.4930 | Yes | ||
16 | ARFIP2 | 1850301 4670180 | 751 | 0.489 | 0.5017 | Yes | ||
17 | CEBPB | 2970019 | 760 | 0.485 | 0.5135 | Yes | ||
18 | RHEBL1 | 2810576 | 820 | 0.460 | 0.5219 | Yes | ||
19 | MTMR3 | 1050014 4920180 | 853 | 0.450 | 0.5314 | Yes | ||
20 | MYL6 | 60563 6100152 | 928 | 0.423 | 0.5381 | Yes | ||
21 | CDC42EP4 | 4150338 | 1011 | 0.397 | 0.5436 | Yes | ||
22 | GRWD1 | 6350528 | 1043 | 0.387 | 0.5517 | Yes | ||
23 | MRPS18B | 5570086 | 1276 | 0.340 | 0.5477 | No | ||
24 | DCTN1 | 1450056 6590022 | 1672 | 0.265 | 0.5329 | No | ||
25 | FOXP4 | 6290022 | 1874 | 0.235 | 0.5279 | No | ||
26 | PEX16 | 4560044 | 1911 | 0.229 | 0.5318 | No | ||
27 | ARHGDIB | 4730433 | 2088 | 0.204 | 0.5273 | No | ||
28 | CLIC1 | 110600 | 2161 | 0.194 | 0.5283 | No | ||
29 | STAT6 | 1190010 5720019 | 2189 | 0.191 | 0.5317 | No | ||
30 | TYRO3 | 3130193 | 2386 | 0.166 | 0.5252 | No | ||
31 | DPYSL2 | 2100427 3130112 5700324 | 2691 | 0.133 | 0.5121 | No | ||
32 | SPI1 | 1410397 | 2778 | 0.125 | 0.5106 | No | ||
33 | RAB10 | 2360008 5890020 | 2970 | 0.108 | 0.5029 | No | ||
34 | ITPR3 | 4010632 | 3022 | 0.105 | 0.5028 | No | ||
35 | SYNPO2L | 5390719 | 3296 | 0.088 | 0.4902 | No | ||
36 | AP1G2 | 780458 2690068 | 3413 | 0.081 | 0.4860 | No | ||
37 | CLSTN3 | 2350685 | 3453 | 0.079 | 0.4858 | No | ||
38 | LBX1 | 1300164 4060204 | 3494 | 0.077 | 0.4856 | No | ||
39 | PVRL1 | 2570167 5220519 5890500 3190309 | 3511 | 0.076 | 0.4867 | No | ||
40 | TCF1 | 5390022 | 3571 | 0.073 | 0.4853 | No | ||
41 | PDGFB | 3060440 6370008 | 3647 | 0.070 | 0.4830 | No | ||
42 | DDR1 | 2060044 5220180 | 3665 | 0.069 | 0.4838 | No | ||
43 | SLCO3A1 | 1050408 2370156 6110072 | 3872 | 0.061 | 0.4742 | No | ||
44 | RPS10 | 4560673 | 3999 | 0.058 | 0.4688 | No | ||
45 | MAP1A | 4920576 | 4047 | 0.056 | 0.4677 | No | ||
46 | TBCC | 4810021 | 4074 | 0.055 | 0.4677 | No | ||
47 | IMPDH2 | 5220138 | 4129 | 0.053 | 0.4661 | No | ||
48 | NR1D1 | 2360471 770746 6590204 | 4145 | 0.053 | 0.4666 | No | ||
49 | LPHN1 | 1400113 3130301 | 4202 | 0.051 | 0.4648 | No | ||
50 | A2BP1 | 2370390 4590593 5550014 | 4412 | 0.046 | 0.4547 | No | ||
51 | NRGN | 4280433 | 4596 | 0.041 | 0.4458 | No | ||
52 | SYTL2 | 580097 5390576 6770603 | 4615 | 0.041 | 0.4458 | No | ||
53 | PLCB3 | 4670402 | 4747 | 0.038 | 0.4397 | No | ||
54 | ATE1 | 290491 6940722 | 4767 | 0.038 | 0.4396 | No | ||
55 | LDLR | 5670386 | 4814 | 0.037 | 0.4381 | No | ||
56 | PKP3 | 3710048 | 4836 | 0.037 | 0.4378 | No | ||
57 | HOXB2 | 6450592 | 4896 | 0.036 | 0.4355 | No | ||
58 | ABCG4 | 3440458 | 5097 | 0.032 | 0.4255 | No | ||
59 | LRCH4 | 5220279 6510026 | 5192 | 0.031 | 0.4212 | No | ||
60 | TGFB1I1 | 2060288 6550450 | 5401 | 0.028 | 0.4106 | No | ||
61 | INPP4A | 510215 1090541 4850093 6100519 | 5446 | 0.027 | 0.4089 | No | ||
62 | H2AFY | 4730750 | 5489 | 0.027 | 0.4073 | No | ||
63 | BCL6B | 60047 | 6020 | 0.021 | 0.3791 | No | ||
64 | HOXA3 | 3610632 6020358 | 6022 | 0.021 | 0.3795 | No | ||
65 | KLF12 | 1660095 4810288 5340546 6520286 | 6125 | 0.020 | 0.3745 | No | ||
66 | LGP2 | 4480338 | 6480 | 0.017 | 0.3557 | No | ||
67 | SMTN | 670563 1190438 | 6612 | 0.016 | 0.3490 | No | ||
68 | FLNC | 2360048 5050270 | 6686 | 0.015 | 0.3454 | No | ||
69 | NEUROD2 | 5290097 | 6709 | 0.015 | 0.3446 | No | ||
70 | MACF1 | 1340132 2370176 2900750 6590364 | 6737 | 0.015 | 0.3435 | No | ||
71 | DLGAP4 | 4570672 5690161 | 6831 | 0.014 | 0.3388 | No | ||
72 | MT4 | 4780338 | 6865 | 0.014 | 0.3374 | No | ||
73 | KCNK7 | 4230576 | 6932 | 0.014 | 0.3342 | No | ||
74 | EPO | 940180 | 6985 | 0.013 | 0.3317 | No | ||
75 | AGER | 5860538 5910180 | 7063 | 0.013 | 0.3278 | No | ||
76 | ATP6V0C | 1780609 | 7091 | 0.013 | 0.3267 | No | ||
77 | PTRF | 2260204 | 7451 | 0.011 | 0.3075 | No | ||
78 | CRLF1 | 3520092 | 7483 | 0.011 | 0.3061 | No | ||
79 | FADS3 | 3120079 | 7553 | 0.010 | 0.3026 | No | ||
80 | RKHD3 | 6180471 | 7952 | 0.009 | 0.2812 | No | ||
81 | HOXC4 | 1940193 | 8556 | 0.006 | 0.2487 | No | ||
82 | ERF | 110551 1770278 | 8622 | 0.006 | 0.2453 | No | ||
83 | FBXO24 | 1230132 4610121 | 8765 | 0.006 | 0.2378 | No | ||
84 | HIF1A | 5670605 | 8842 | 0.005 | 0.2338 | No | ||
85 | HOXA11 | 6980133 | 8875 | 0.005 | 0.2322 | No | ||
86 | GREM1 | 3940180 | 8905 | 0.005 | 0.2307 | No | ||
87 | LMX1A | 2810239 5690324 | 9247 | 0.004 | 0.2123 | No | ||
88 | FABP6 | 7000278 | 9390 | 0.004 | 0.2047 | No | ||
89 | NFATC4 | 2470735 | 9463 | 0.004 | 0.2009 | No | ||
90 | EVX1 | 1980471 | 9519 | 0.003 | 0.1980 | No | ||
91 | NF1 | 6980433 | 9709 | 0.003 | 0.1879 | No | ||
92 | TIMP4 | 6110433 | 9730 | 0.003 | 0.1868 | No | ||
93 | LRRN1 | 3290154 | 9805 | 0.003 | 0.1829 | No | ||
94 | PDE5A | 130072 | 9818 | 0.003 | 0.1823 | No | ||
95 | ANXA9 | 1190195 | 10000 | 0.002 | 0.1725 | No | ||
96 | ESR1 | 4060372 5860193 | 10107 | 0.002 | 0.1668 | No | ||
97 | KCNMB1 | 4760139 | 10316 | 0.001 | 0.1556 | No | ||
98 | HOXD10 | 6100039 | 10377 | 0.001 | 0.1524 | No | ||
99 | ZFP36L1 | 2510138 4120048 | 10657 | 0.000 | 0.1372 | No | ||
100 | PAX3 | 50551 | 11246 | -0.001 | 0.1054 | No | ||
101 | SLC2A4 | 540441 | 11568 | -0.002 | 0.0880 | No | ||
102 | SALL1 | 5420020 7050195 | 11659 | -0.003 | 0.0832 | No | ||
103 | CACNB1 | 2940427 3710487 | 11676 | -0.003 | 0.0824 | No | ||
104 | GNAO1 | 2510292 6590487 | 11840 | -0.003 | 0.0737 | No | ||
105 | PLA2G3 | 5130739 | 11926 | -0.004 | 0.0692 | No | ||
106 | HYAL1 | 3850341 | 12041 | -0.004 | 0.0631 | No | ||
107 | SIX4 | 6760022 | 12173 | -0.005 | 0.0561 | No | ||
108 | SERPINI1 | 2940468 | 12210 | -0.005 | 0.0543 | No | ||
109 | EMX2 | 1660092 | 12224 | -0.005 | 0.0537 | No | ||
110 | DUSP8 | 6650039 | 12266 | -0.005 | 0.0516 | No | ||
111 | GRID2 | 2680242 | 12481 | -0.006 | 0.0401 | No | ||
112 | GFAP | 2060092 | 12518 | -0.006 | 0.0383 | No | ||
113 | GRIA1 | 1340152 3780750 4920440 | 12645 | -0.007 | 0.0316 | No | ||
114 | GAP43 | 3130504 | 12646 | -0.007 | 0.0318 | No | ||
115 | TCF2 | 870338 5050632 | 12666 | -0.007 | 0.0309 | No | ||
116 | GUCA2B | 4200014 | 12726 | -0.007 | 0.0279 | No | ||
117 | SLC24A1 | 1240463 | 12770 | -0.007 | 0.0258 | No | ||
118 | LIN28 | 6590672 | 12789 | -0.007 | 0.0250 | No | ||
119 | SLC4A10 | 2060670 | 13058 | -0.009 | 0.0107 | No | ||
120 | CACNA1D | 1740315 4730731 | 13428 | -0.011 | -0.0091 | No | ||
121 | SLC4A1 | 6290577 | 13442 | -0.011 | -0.0095 | No | ||
122 | KCNN3 | 6520600 6420138 | 13523 | -0.012 | -0.0135 | No | ||
123 | MEOX2 | 6400288 | 13555 | -0.012 | -0.0149 | No | ||
124 | DHH | 2120433 | 13599 | -0.012 | -0.0169 | No | ||
125 | TEAD2 | 6450079 | 13687 | -0.013 | -0.0213 | No | ||
126 | KIF1B | 1240494 2370139 4570270 6510102 | 13933 | -0.016 | -0.0342 | No | ||
127 | SREBF2 | 3390692 | 14121 | -0.018 | -0.0439 | No | ||
128 | RARG | 6760136 | 14226 | -0.020 | -0.0490 | No | ||
129 | LRP8 | 3610746 5360035 | 14322 | -0.021 | -0.0537 | No | ||
130 | POU4F2 | 2120195 2570022 | 14328 | -0.021 | -0.0534 | No | ||
131 | DSG4 | 3990605 6400736 | 14362 | -0.022 | -0.0546 | No | ||
132 | TRAF4 | 3060041 4920528 6980286 | 14419 | -0.023 | -0.0571 | No | ||
133 | ENO2 | 2320068 | 14423 | -0.023 | -0.0567 | No | ||
134 | SOX12 | 1780037 | 14611 | -0.026 | -0.0662 | No | ||
135 | CLASP1 | 6860279 | 15001 | -0.037 | -0.0863 | No | ||
136 | CLDN5 | 6510717 | 15007 | -0.038 | -0.0857 | No | ||
137 | BAZ2A | 730184 | 15091 | -0.041 | -0.0891 | No | ||
138 | ZIC4 | 1500082 | 15173 | -0.044 | -0.0924 | No | ||
139 | REL | 360707 | 15264 | -0.048 | -0.0961 | No | ||
140 | SLC39A14 | 670300 1400093 1990711 | 15312 | -0.050 | -0.0974 | No | ||
141 | GPR85 | 5130750 5910020 | 15438 | -0.056 | -0.1027 | No | ||
142 | B4GALT2 | 780037 | 15452 | -0.057 | -0.1020 | No | ||
143 | FBS1 | 2570520 | 15487 | -0.060 | -0.1024 | No | ||
144 | PCF11 | 1240180 | 15502 | -0.061 | -0.1016 | No | ||
145 | PACSIN3 | 4540369 4540400 5360037 6940129 | 15545 | -0.063 | -0.1023 | No | ||
146 | MAPKAPK3 | 630520 | 15582 | -0.066 | -0.1026 | No | ||
147 | EN1 | 5360168 7050025 | 15637 | -0.069 | -0.1038 | No | ||
148 | DYRK1A | 3190181 | 15694 | -0.073 | -0.1050 | No | ||
149 | FXYD1 | 1400239 6560129 | 15735 | -0.076 | -0.1052 | No | ||
150 | NTRK3 | 4050687 4070167 4610026 6100484 | 15820 | -0.083 | -0.1077 | No | ||
151 | TRERF1 | 6370017 6940138 | 15841 | -0.084 | -0.1067 | No | ||
152 | STX1A | 3060273 | 15848 | -0.084 | -0.1049 | No | ||
153 | PHF15 | 6550066 6860673 | 15924 | -0.090 | -0.1067 | No | ||
154 | MYH10 | 2640673 | 16127 | -0.107 | -0.1149 | No | ||
155 | YWHAQ | 6760524 | 16174 | -0.112 | -0.1146 | No | ||
156 | NFAT5 | 2510411 5890195 6550152 | 16428 | -0.140 | -0.1248 | No | ||
157 | LASP1 | 1690528 2190341 6420341 | 16560 | -0.159 | -0.1279 | No | ||
158 | RBX1 | 2120010 2340047 | 16567 | -0.160 | -0.1242 | No | ||
159 | SIPA1L2 | 4850731 | 16585 | -0.163 | -0.1210 | No | ||
160 | JUP | 2510671 | 17016 | -0.233 | -0.1385 | No | ||
161 | ANP32A | 510044 1580095 2680037 | 17154 | -0.264 | -0.1393 | No | ||
162 | SLIT3 | 7100132 | 17197 | -0.273 | -0.1347 | No | ||
163 | ZFYVE1 | 60440 | 17250 | -0.289 | -0.1302 | No | ||
164 | NFIX | 2450152 | 17251 | -0.289 | -0.1229 | No | ||
165 | DDX6 | 2630025 6770408 | 17369 | -0.323 | -0.1211 | No | ||
166 | PDCD10 | 4760500 | 17634 | -0.404 | -0.1253 | No | ||
167 | NMT1 | 5810152 | 17748 | -0.444 | -0.1202 | No | ||
168 | NSF | 4070075 | 17782 | -0.456 | -0.1105 | No | ||
169 | MMP14 | 670079 | 17840 | -0.481 | -0.1015 | No | ||
170 | ATP6V1A | 6590242 | 17877 | -0.493 | -0.0911 | No | ||
171 | KPNB1 | 1690138 | 18073 | -0.602 | -0.0865 | No | ||
172 | FCHSD2 | 5720092 | 18106 | -0.615 | -0.0727 | No | ||
173 | EMP1 | 4120438 | 18184 | -0.662 | -0.0603 | No | ||
174 | PIAS1 | 5340301 | 18311 | -0.780 | -0.0475 | No | ||
175 | EIF4G2 | 3800575 6860184 | 18522 | -1.204 | -0.0285 | No | ||
176 | PPP1R10 | 110136 3170725 3610484 | 18539 | -1.334 | 0.0042 | No |