Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | 0.5621637 |
Normalized Enrichment Score (NES) | 1.438827 |
Nominal p-value | 0.011075949 |
FDR q-value | 0.8338141 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MFN2 | 2260195 6100164 | 12 | 3.462 | 0.1032 | Yes | ||
2 | SSBP3 | 870717 1050377 7040551 | 92 | 1.522 | 0.1445 | Yes | ||
3 | DGKZ | 3460041 6400129 | 133 | 1.227 | 0.1792 | Yes | ||
4 | SLAMF9 | 3710300 | 137 | 1.201 | 0.2150 | Yes | ||
5 | CD5 | 6590338 | 271 | 0.931 | 0.2357 | Yes | ||
6 | IL2RA | 6620450 | 305 | 0.888 | 0.2606 | Yes | ||
7 | CTSW | 360368 | 307 | 0.884 | 0.2870 | Yes | ||
8 | CDKN2C | 5050750 5130148 | 376 | 0.763 | 0.3062 | Yes | ||
9 | POU2AF1 | 5690242 | 427 | 0.694 | 0.3243 | Yes | ||
10 | POLD4 | 2320082 | 466 | 0.660 | 0.3421 | Yes | ||
11 | TCIRG1 | 4590524 5910079 6900619 | 485 | 0.642 | 0.3603 | Yes | ||
12 | TNNI2 | 5910739 | 487 | 0.638 | 0.3794 | Yes | ||
13 | MAPKAPK2 | 2850500 | 519 | 0.619 | 0.3963 | Yes | ||
14 | UNC93B1 | 430152 | 600 | 0.563 | 0.4089 | Yes | ||
15 | TYSND1 | 2940273 | 648 | 0.532 | 0.4223 | Yes | ||
16 | SELL | 1190500 | 678 | 0.519 | 0.4362 | Yes | ||
17 | RHOG | 6760575 | 684 | 0.516 | 0.4514 | Yes | ||
18 | ELOVL1 | 2450019 4760138 5340685 | 778 | 0.478 | 0.4607 | Yes | ||
19 | GPD1 | 2480095 | 783 | 0.474 | 0.4747 | Yes | ||
20 | FCGR3A | 3840184 | 817 | 0.462 | 0.4868 | Yes | ||
21 | BLNK | 70288 6590092 | 839 | 0.456 | 0.4993 | Yes | ||
22 | ZNF289 | 3610390 3870711 3940138 5340373 | 1014 | 0.396 | 0.5018 | Yes | ||
23 | LPXN | 2360142 | 1170 | 0.359 | 0.5041 | Yes | ||
24 | PTPN6 | 4230128 | 1287 | 0.337 | 0.5080 | Yes | ||
25 | SRRM1 | 6110025 | 1499 | 0.295 | 0.5054 | Yes | ||
26 | NDUFS2 | 4850020 6200402 | 1511 | 0.292 | 0.5135 | Yes | ||
27 | SLC2A3 | 1990377 | 1539 | 0.287 | 0.5207 | Yes | ||
28 | PRF1 | 6660309 | 1556 | 0.285 | 0.5283 | Yes | ||
29 | CAP1 | 2650278 | 1655 | 0.267 | 0.5310 | Yes | ||
30 | MAP4K2 | 4200037 | 1743 | 0.254 | 0.5339 | Yes | ||
31 | ESRRA | 6550242 | 1796 | 0.247 | 0.5385 | Yes | ||
32 | CD53 | 5550162 | 1893 | 0.232 | 0.5403 | Yes | ||
33 | VCAM1 | 2900450 | 1949 | 0.222 | 0.5440 | Yes | ||
34 | RPS6KA4 | 2190524 | 2037 | 0.211 | 0.5456 | Yes | ||
35 | EPC1 | 1570050 5290095 6900193 | 2078 | 0.205 | 0.5496 | Yes | ||
36 | ARHGDIB | 4730433 | 2088 | 0.204 | 0.5552 | Yes | ||
37 | ADRBK1 | 1340333 | 2249 | 0.183 | 0.5520 | Yes | ||
38 | LCK | 3360142 | 2265 | 0.181 | 0.5566 | Yes | ||
39 | IL18BP | 3450128 | 2372 | 0.167 | 0.5559 | Yes | ||
40 | LAG3 | 6860112 | 2500 | 0.152 | 0.5536 | Yes | ||
41 | PIK4CB | 510450 1780452 | 2540 | 0.149 | 0.5559 | Yes | ||
42 | SYTL1 | 510487 | 2663 | 0.136 | 0.5534 | Yes | ||
43 | DPP3 | 2680725 3780670 | 2690 | 0.133 | 0.5560 | Yes | ||
44 | KCNQ1 | 1580050 6860441 | 2753 | 0.128 | 0.5564 | Yes | ||
45 | SPI1 | 1410397 | 2778 | 0.125 | 0.5589 | Yes | ||
46 | LRFN4 | 5670368 | 2820 | 0.121 | 0.5603 | Yes | ||
47 | SIPA1 | 5220687 | 2890 | 0.115 | 0.5600 | Yes | ||
48 | CYR61 | 1240408 5290026 4120452 6550008 | 2959 | 0.109 | 0.5596 | Yes | ||
49 | ITPKB | 2900195 7100039 | 2975 | 0.108 | 0.5620 | Yes | ||
50 | ZRANB1 | 510373 4540278 | 3083 | 0.102 | 0.5593 | Yes | ||
51 | ETV3 | 5360487 | 3098 | 0.101 | 0.5615 | Yes | ||
52 | WASF2 | 4850592 | 3142 | 0.098 | 0.5622 | Yes | ||
53 | NUMA1 | 6520576 | 3219 | 0.092 | 0.5608 | No | ||
54 | LTBR | 2450341 | 3387 | 0.083 | 0.5542 | No | ||
55 | SLC26A9 | 3440722 5340088 7510093 | 3412 | 0.081 | 0.5554 | No | ||
56 | BCL2L14 | 2940279 | 3422 | 0.081 | 0.5573 | No | ||
57 | CENTD2 | 60408 2510156 6100494 | 3642 | 0.070 | 0.5476 | No | ||
58 | MMRN2 | 1740047 | 3670 | 0.069 | 0.5482 | No | ||
59 | SORL1 | 630204 | 3720 | 0.067 | 0.5475 | No | ||
60 | ELAVL4 | 50735 3360086 5220167 | 3806 | 0.064 | 0.5449 | No | ||
61 | SELP | 6040193 | 3823 | 0.064 | 0.5459 | No | ||
62 | CTSS | 1740056 | 3943 | 0.059 | 0.5412 | No | ||
63 | CD3E | 3800056 | 4321 | 0.048 | 0.5222 | No | ||
64 | GPR120 | 2350398 | 4455 | 0.045 | 0.5164 | No | ||
65 | NRGN | 4280433 | 4596 | 0.041 | 0.5100 | No | ||
66 | SLC30A7 | 2230463 | 4722 | 0.039 | 0.5044 | No | ||
67 | PLCB3 | 4670402 | 4747 | 0.038 | 0.5043 | No | ||
68 | RPS3 | 1570017 2370170 | 5093 | 0.032 | 0.4866 | No | ||
69 | DMBT1 | 7050270 | 5222 | 0.030 | 0.4805 | No | ||
70 | CUGBP1 | 450292 510022 7050176 7050215 | 5365 | 0.028 | 0.4737 | No | ||
71 | EPHA2 | 5890056 | 5484 | 0.027 | 0.4681 | No | ||
72 | PRDX6 | 4920397 6380601 | 5682 | 0.024 | 0.4581 | No | ||
73 | HHEX | 2340575 | 5757 | 0.023 | 0.4548 | No | ||
74 | ST7L | 840735 2360576 | 5787 | 0.023 | 0.4539 | No | ||
75 | IVL | 4560500 | 5899 | 0.022 | 0.4486 | No | ||
76 | MARK1 | 450484 | 6011 | 0.021 | 0.4432 | No | ||
77 | RUNX3 | 3800546 | 6033 | 0.021 | 0.4427 | No | ||
78 | PBXIP1 | 70131 | 6772 | 0.015 | 0.4031 | No | ||
79 | LALBA | 6940685 | 7169 | 0.012 | 0.3820 | No | ||
80 | VPS11 | 1090048 6040372 | 7203 | 0.012 | 0.3806 | No | ||
81 | PGM2L1 | 2350035 | 7207 | 0.012 | 0.3808 | No | ||
82 | IL18 | 6180039 | 7249 | 0.012 | 0.3789 | No | ||
83 | ADAMTS4 | 430435 | 7329 | 0.011 | 0.3750 | No | ||
84 | KAZALD1 | 380603 | 7525 | 0.011 | 0.3648 | No | ||
85 | FGF23 | 510746 | 7852 | 0.009 | 0.3474 | No | ||
86 | PAX6 | 1190025 | 7910 | 0.009 | 0.3445 | No | ||
87 | PDGFD | 60438 | 8108 | 0.008 | 0.3341 | No | ||
88 | FUCA1 | 610075 | 8112 | 0.008 | 0.3342 | No | ||
89 | IPO7 | 2190746 | 8359 | 0.007 | 0.3211 | No | ||
90 | XPNPEP1 | 2640750 3850315 6200242 | 8939 | 0.005 | 0.2899 | No | ||
91 | CPNE8 | 7040039 | 9158 | 0.004 | 0.2782 | No | ||
92 | NCF2 | 540129 2370441 2650133 | 9695 | 0.003 | 0.2492 | No | ||
93 | ANKRD1 | 4850685 | 9740 | 0.003 | 0.2469 | No | ||
94 | EHF | 4560088 | 9976 | 0.002 | 0.2343 | No | ||
95 | GAB2 | 1410280 2340520 4280040 | 10091 | 0.002 | 0.2281 | No | ||
96 | MMP7 | 1780497 | 10127 | 0.002 | 0.2263 | No | ||
97 | TAF5 | 3450288 5890193 6860435 | 10196 | 0.001 | 0.2226 | No | ||
98 | GPA33 | 2650044 | 10543 | 0.001 | 0.2039 | No | ||
99 | AKT3 | 1580270 3290278 | 10642 | 0.000 | 0.1986 | No | ||
100 | NCAM1 | 3140026 | 11004 | -0.001 | 0.1791 | No | ||
101 | CACNA1E | 840253 | 11094 | -0.001 | 0.1743 | No | ||
102 | BDNF | 2940128 3520368 | 12639 | -0.007 | 0.0908 | No | ||
103 | RNASEL | 2340133 | 12685 | -0.007 | 0.0886 | No | ||
104 | XCL1 | 3800504 | 12744 | -0.007 | 0.0857 | No | ||
105 | LIN28 | 6590672 | 12789 | -0.007 | 0.0835 | No | ||
106 | CMAS | 2190129 | 12857 | -0.008 | 0.0801 | No | ||
107 | ELK4 | 460494 940369 4480136 | 13045 | -0.009 | 0.0702 | No | ||
108 | SPRR4 | 5720273 | 13199 | -0.010 | 0.0622 | No | ||
109 | FUT11 | 6040692 | 13465 | -0.011 | 0.0482 | No | ||
110 | GRIN2B | 3800333 | 13618 | -0.013 | 0.0403 | No | ||
111 | CAPZA1 | 3140390 | 13647 | -0.013 | 0.0392 | No | ||
112 | SLC41A1 | 1230528 | 13663 | -0.013 | 0.0388 | No | ||
113 | HIPK1 | 110193 | 13664 | -0.013 | 0.0392 | No | ||
114 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | 0.0333 | No | ||
115 | SV2A | 1450039 5570685 | 14521 | -0.024 | -0.0060 | No | ||
116 | RAB39 | 430524 | 14794 | -0.031 | -0.0198 | No | ||
117 | CBL | 6380068 | 14966 | -0.036 | -0.0280 | No | ||
118 | ANK3 | 1500161 2900435 4210154 6400100 | 15072 | -0.040 | -0.0325 | No | ||
119 | PAFAH2 | 3140451 5720593 6510014 | 15083 | -0.040 | -0.0318 | No | ||
120 | PICALM | 1940280 | 15092 | -0.041 | -0.0310 | No | ||
121 | RIN1 | 510593 | 15099 | -0.041 | -0.0301 | No | ||
122 | CAMK1D | 1660100 2350309 | 15141 | -0.043 | -0.0310 | No | ||
123 | LAMC1 | 4730025 | 15203 | -0.045 | -0.0330 | No | ||
124 | KCNAB2 | 4850315 | 15218 | -0.046 | -0.0323 | No | ||
125 | CTBP2 | 430309 3710079 | 15290 | -0.049 | -0.0347 | No | ||
126 | CD69 | 380167 4730088 | 15360 | -0.052 | -0.0369 | No | ||
127 | SNCG | 3120725 | 15445 | -0.057 | -0.0397 | No | ||
128 | FEN1 | 1770541 | 15483 | -0.059 | -0.0400 | No | ||
129 | IRAK4 | 5390156 6130594 | 15554 | -0.064 | -0.0418 | No | ||
130 | TCEB3 | 5890156 | 15600 | -0.066 | -0.0423 | No | ||
131 | GFI1 | 730180 | 15648 | -0.070 | -0.0427 | No | ||
132 | ITPR2 | 5360128 | 15705 | -0.074 | -0.0435 | No | ||
133 | ABLIM1 | 580170 3710338 6520504 | 15799 | -0.081 | -0.0462 | No | ||
134 | SLC35C1 | 4540154 | 16091 | -0.104 | -0.0588 | No | ||
135 | ZDHHC5 | 1690711 | 16093 | -0.104 | -0.0558 | No | ||
136 | VDAC2 | 7000215 | 16110 | -0.105 | -0.0535 | No | ||
137 | PUM1 | 6130500 | 16146 | -0.109 | -0.0521 | No | ||
138 | LZTS2 | 2260440 | 16181 | -0.113 | -0.0506 | No | ||
139 | TNFRSF19L | 1170168 1190358 5670270 | 16188 | -0.113 | -0.0475 | No | ||
140 | MARK2 | 7210608 | 16229 | -0.117 | -0.0462 | No | ||
141 | EXTL2 | 5050433 | 16438 | -0.141 | -0.0532 | No | ||
142 | TRIM33 | 580619 2230280 3990433 6200747 | 16523 | -0.154 | -0.0531 | No | ||
143 | MR1 | 3850037 | 16573 | -0.161 | -0.0509 | No | ||
144 | CDC14A | 4050132 | 16605 | -0.167 | -0.0476 | No | ||
145 | ARF3 | 3710446 | 16614 | -0.168 | -0.0430 | No | ||
146 | DCLRE1C | 1450041 2360091 3290671 3390739 | 16822 | -0.200 | -0.0482 | No | ||
147 | SEC24C | 6980707 | 16921 | -0.218 | -0.0470 | No | ||
148 | SPATA6 | 4590373 | 16965 | -0.225 | -0.0426 | No | ||
149 | NT5C2 | 4280735 4670528 | 16994 | -0.231 | -0.0372 | No | ||
150 | FLI1 | 3990142 | 16999 | -0.231 | -0.0305 | No | ||
151 | GATA3 | 6130068 | 17054 | -0.243 | -0.0261 | No | ||
152 | TMEM24 | 5860039 | 17270 | -0.295 | -0.0289 | No | ||
153 | LRMP | 6290193 | 17299 | -0.303 | -0.0214 | No | ||
154 | PTPRC | 130402 5290148 | 17327 | -0.312 | -0.0135 | No | ||
155 | CD84 | 1780168 | 17426 | -0.337 | -0.0087 | No | ||
156 | GTF2H1 | 2570746 2650148 | 17587 | -0.381 | -0.0059 | No | ||
157 | TRIM8 | 6130441 | 17883 | -0.496 | -0.0070 | No | ||
158 | INPPL1 | 110717 3120164 | 17906 | -0.509 | 0.0070 | No | ||
159 | PRKACB | 4210170 | 18473 | -1.046 | 0.0077 | No |