Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$MYOD_Q6 |
Enrichment Score (ES) | 0.53597856 |
Normalized Enrichment Score (NES) | 1.3659852 |
Nominal p-value | 0.016528925 |
FDR q-value | 0.74451715 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.1164 | Yes | ||
2 | IGF2 | 6510020 | 26 | 2.564 | 0.2206 | Yes | ||
3 | CKM | 1450524 | 80 | 1.575 | 0.2820 | Yes | ||
4 | HES6 | 540411 6550504 | 96 | 1.504 | 0.3425 | Yes | ||
5 | TUFT1 | 540047 2370010 | 143 | 1.181 | 0.3881 | Yes | ||
6 | HEYL | 5860528 | 264 | 0.937 | 0.4198 | Yes | ||
7 | GMPR | 3990022 | 270 | 0.933 | 0.4576 | Yes | ||
8 | POLD4 | 2320082 | 466 | 0.660 | 0.4739 | Yes | ||
9 | SELL | 1190500 | 678 | 0.519 | 0.4837 | Yes | ||
10 | ELOVL1 | 2450019 4760138 5340685 | 778 | 0.478 | 0.4978 | Yes | ||
11 | GFRA1 | 3610152 | 780 | 0.478 | 0.5172 | Yes | ||
12 | PRKACA | 2640731 4050048 | 790 | 0.471 | 0.5360 | Yes | ||
13 | HMGA1 | 6580408 | 1226 | 0.349 | 0.5266 | No | ||
14 | PSTPIP1 | 3190156 | 1505 | 0.293 | 0.5235 | No | ||
15 | TAGAP | 3290433 | 1825 | 0.242 | 0.5161 | No | ||
16 | ARID5A | 2450133 | 1827 | 0.242 | 0.5259 | No | ||
17 | PPP2R4 | 670280 2900097 | 2021 | 0.213 | 0.5241 | No | ||
18 | CRELD1 | 2060253 | 2309 | 0.176 | 0.5158 | No | ||
19 | BCL9 | 7100112 | 2431 | 0.161 | 0.5158 | No | ||
20 | TEC | 1400576 | 2591 | 0.144 | 0.5130 | No | ||
21 | DEF6 | 840593 | 2592 | 0.144 | 0.5189 | No | ||
22 | CDH1 | 1940736 | 2664 | 0.136 | 0.5206 | No | ||
23 | SPI1 | 1410397 | 2778 | 0.125 | 0.5196 | No | ||
24 | NCKIPSD | 2940156 | 2829 | 0.120 | 0.5218 | No | ||
25 | SIPA1 | 5220687 | 2890 | 0.115 | 0.5232 | No | ||
26 | INVS | 4200632 6620528 | 2913 | 0.113 | 0.5266 | No | ||
27 | ITPR3 | 4010632 | 3022 | 0.105 | 0.5250 | No | ||
28 | TNFRSF21 | 6380100 | 3175 | 0.096 | 0.5207 | No | ||
29 | ITGB4 | 1740021 3840482 | 3214 | 0.093 | 0.5225 | No | ||
30 | ACTN3 | 3140541 6480598 | 3479 | 0.078 | 0.5113 | No | ||
31 | SYT4 | 5080193 | 3521 | 0.076 | 0.5122 | No | ||
32 | PDGFB | 3060440 6370008 | 3647 | 0.070 | 0.5083 | No | ||
33 | ELAVL4 | 50735 3360086 5220167 | 3806 | 0.064 | 0.5023 | No | ||
34 | USP2 | 1190292 1240253 4850035 | 3858 | 0.062 | 0.5021 | No | ||
35 | NR2E1 | 4730288 | 3876 | 0.061 | 0.5037 | No | ||
36 | POFUT1 | 1570458 | 3909 | 0.060 | 0.5044 | No | ||
37 | SCG2 | 5670438 130671 | 3977 | 0.058 | 0.5031 | No | ||
38 | CRAT | 540020 2060364 3520148 | 4138 | 0.053 | 0.4966 | No | ||
39 | TBR1 | 5130053 | 4223 | 0.050 | 0.4941 | No | ||
40 | PHACTR3 | 3850435 5900445 | 4313 | 0.048 | 0.4913 | No | ||
41 | MDGA1 | 1170139 | 4419 | 0.046 | 0.4874 | No | ||
42 | NKX6-2 | 2450332 3120333 | 4448 | 0.045 | 0.4877 | No | ||
43 | RND1 | 5080300 | 4469 | 0.045 | 0.4885 | No | ||
44 | GGN | 1410528 4210082 5290170 | 4562 | 0.042 | 0.4852 | No | ||
45 | PRKAG2 | 2340100 | 4796 | 0.037 | 0.4741 | No | ||
46 | SYNGR1 | 5130452 6650056 | 4853 | 0.036 | 0.4726 | No | ||
47 | HN1 | 3360156 | 4859 | 0.036 | 0.4738 | No | ||
48 | CASKIN2 | 2030113 | 4884 | 0.036 | 0.4739 | No | ||
49 | MLLT6 | 3870168 | 5190 | 0.031 | 0.4587 | No | ||
50 | PROX1 | 4210193 | 5254 | 0.030 | 0.4565 | No | ||
51 | NOL4 | 5050446 5360519 | 5301 | 0.029 | 0.4552 | No | ||
52 | CUGBP1 | 450292 510022 7050176 7050215 | 5365 | 0.028 | 0.4529 | No | ||
53 | RIMS2 | 670725 | 6075 | 0.020 | 0.4153 | No | ||
54 | NPPC | 2320647 | 6112 | 0.020 | 0.4141 | No | ||
55 | FSCN2 | 1230039 | 6126 | 0.020 | 0.4142 | No | ||
56 | AP4S1 | 4730292 | 6135 | 0.020 | 0.4146 | No | ||
57 | POU3F3 | 6400047 | 6293 | 0.018 | 0.4068 | No | ||
58 | CYP26A1 | 380022 2690600 | 6559 | 0.016 | 0.3931 | No | ||
59 | CASQ1 | 6290035 7000707 | 6663 | 0.015 | 0.3882 | No | ||
60 | ERBB3 | 5890372 | 6738 | 0.015 | 0.3848 | No | ||
61 | BEX2 | 5670433 | 7047 | 0.013 | 0.3686 | No | ||
62 | ERBB4 | 4610400 4810017 | 7308 | 0.012 | 0.3550 | No | ||
63 | KAZALD1 | 380603 | 7525 | 0.011 | 0.3437 | No | ||
64 | CDON | 540204 | 7629 | 0.010 | 0.3385 | No | ||
65 | HSD11B2 | 5900053 | 7646 | 0.010 | 0.3381 | No | ||
66 | ANK2 | 6510546 | 7653 | 0.010 | 0.3381 | No | ||
67 | MYOZ3 | 1990138 | 7721 | 0.010 | 0.3349 | No | ||
68 | ALG6 | 4060131 | 7864 | 0.009 | 0.3276 | No | ||
69 | LRAT | 5130603 | 7873 | 0.009 | 0.3275 | No | ||
70 | ATOH7 | 5550121 | 8156 | 0.008 | 0.3125 | No | ||
71 | CMYA1 | 6900632 | 8212 | 0.008 | 0.3099 | No | ||
72 | INHA | 6100102 | 8345 | 0.007 | 0.3030 | No | ||
73 | TGM1 | 1090500 | 8365 | 0.007 | 0.3023 | No | ||
74 | TTN | 2320161 4670056 6550026 | 8482 | 0.007 | 0.2962 | No | ||
75 | ARHGEF2 | 3360577 | 8534 | 0.006 | 0.2937 | No | ||
76 | HDAC9 | 1990010 2260133 | 8603 | 0.006 | 0.2903 | No | ||
77 | ELAVL3 | 2850014 | 8655 | 0.006 | 0.2878 | No | ||
78 | GATA2 | 6590280 | 8958 | 0.005 | 0.2716 | No | ||
79 | PAK3 | 4210136 | 8968 | 0.005 | 0.2713 | No | ||
80 | MAP3K13 | 3190017 | 9046 | 0.005 | 0.2674 | No | ||
81 | USF1 | 4280156 4610114 6370113 | 9262 | 0.004 | 0.2559 | No | ||
82 | TRPV3 | 540341 | 9327 | 0.004 | 0.2526 | No | ||
83 | TAC4 | 4730070 | 9546 | 0.003 | 0.2409 | No | ||
84 | ARL4A | 6290091 | 9685 | 0.003 | 0.2335 | No | ||
85 | SOST | 1170195 | 9823 | 0.003 | 0.2262 | No | ||
86 | ABL2 | 580021 | 9936 | 0.002 | 0.2202 | No | ||
87 | MTUS1 | 780348 4920609 | 9978 | 0.002 | 0.2181 | No | ||
88 | ASB15 | 450563 | 9980 | 0.002 | 0.2181 | No | ||
89 | CHRND | 840403 2260670 | 10101 | 0.002 | 0.2117 | No | ||
90 | FOXI1 | 3710095 6620195 | 10244 | 0.001 | 0.2041 | No | ||
91 | DPF3 | 2650128 2970168 | 10573 | 0.000 | 0.1863 | No | ||
92 | EFNA1 | 3840672 | 10588 | 0.000 | 0.1856 | No | ||
93 | CCNL2 | 6520167 | 10655 | 0.000 | 0.1820 | No | ||
94 | CHCHD3 | 4200044 | 10941 | -0.001 | 0.1666 | No | ||
95 | PTPRJ | 4010707 | 10981 | -0.001 | 0.1645 | No | ||
96 | RASGRF2 | 1990047 | 11042 | -0.001 | 0.1613 | No | ||
97 | FBXW11 | 6450632 | 11157 | -0.001 | 0.1551 | No | ||
98 | NHLH1 | 6100452 | 11423 | -0.002 | 0.1409 | No | ||
99 | CHRNG | 5860273 | 11581 | -0.002 | 0.1324 | No | ||
100 | SLC12A5 | 1980692 | 11655 | -0.003 | 0.1286 | No | ||
101 | GUCY1A3 | 110253 2640735 4070037 | 11697 | -0.003 | 0.1265 | No | ||
102 | B3GALT2 | 430136 | 11740 | -0.003 | 0.1243 | No | ||
103 | NBL1 | 2480021 | 11882 | -0.003 | 0.1168 | No | ||
104 | NEB | 580735 | 11923 | -0.004 | 0.1148 | No | ||
105 | COL4A3 | 5910075 | 12009 | -0.004 | 0.1104 | No | ||
106 | NPEPPS | 2630731 | 12053 | -0.004 | 0.1082 | No | ||
107 | TREX2 | 4920707 | 12081 | -0.004 | 0.1069 | No | ||
108 | KCNQ4 | 3800438 7050400 | 12378 | -0.005 | 0.0911 | No | ||
109 | GRID2 | 2680242 | 12481 | -0.006 | 0.0858 | No | ||
110 | LIN28 | 6590672 | 12789 | -0.007 | 0.0695 | No | ||
111 | STARD13 | 540722 | 12823 | -0.007 | 0.0680 | No | ||
112 | ANKRD2 | 6590427 | 12826 | -0.007 | 0.0682 | No | ||
113 | DCT | 1090347 3840494 | 12862 | -0.008 | 0.0666 | No | ||
114 | DSCAML1 | 1850403 5550079 | 12963 | -0.008 | 0.0615 | No | ||
115 | EMX1 | 6130537 | 13331 | -0.010 | 0.0420 | No | ||
116 | DSCAM | 1780050 2450731 2810438 | 13347 | -0.011 | 0.0416 | No | ||
117 | SEMA4C | 1980315 | 13389 | -0.011 | 0.0399 | No | ||
118 | FUT8 | 1340068 2340056 | 13420 | -0.011 | 0.0387 | No | ||
119 | HR | 2690095 6200300 | 13466 | -0.011 | 0.0367 | No | ||
120 | KCNN3 | 6520600 6420138 | 13523 | -0.012 | 0.0342 | No | ||
121 | KCNE1L | 4670092 | 13739 | -0.014 | 0.0231 | No | ||
122 | VKORC1L1 | 110220 1400050 | 13799 | -0.014 | 0.0204 | No | ||
123 | PPARGC1A | 4670040 | 13963 | -0.016 | 0.0123 | No | ||
124 | ITGA6 | 3830129 | 14056 | -0.017 | 0.0080 | No | ||
125 | TJP1 | 6350184 | 14069 | -0.017 | 0.0080 | No | ||
126 | RHOBTB1 | 1410010 | 14088 | -0.018 | 0.0078 | No | ||
127 | COL4A4 | 1050541 | 14096 | -0.018 | 0.0081 | No | ||
128 | USP15 | 610592 3520504 | 14108 | -0.018 | 0.0082 | No | ||
129 | SREBF2 | 3390692 | 14121 | -0.018 | 0.0083 | No | ||
130 | FGF17 | 3130022 | 14126 | -0.018 | 0.0088 | No | ||
131 | PLCB1 | 2570050 7100102 | 14194 | -0.019 | 0.0060 | No | ||
132 | CER1 | 840102 | 14237 | -0.020 | 0.0045 | No | ||
133 | MID1 | 4070114 4760458 | 14331 | -0.021 | 0.0003 | No | ||
134 | ASB14 | 5860427 | 14376 | -0.022 | -0.0011 | No | ||
135 | TRIM3 | 5570156 | 14403 | -0.022 | -0.0016 | No | ||
136 | SSH2 | 360056 | 14520 | -0.024 | -0.0069 | No | ||
137 | EIF2C1 | 6900551 | 14712 | -0.029 | -0.0161 | No | ||
138 | HTR7 | 2680176 | 14719 | -0.029 | -0.0153 | No | ||
139 | FBXO32 | 110037 610750 | 14720 | -0.029 | -0.0141 | No | ||
140 | LCN9 | 5050450 | 14771 | -0.030 | -0.0155 | No | ||
141 | HS6ST3 | 5910138 | 14915 | -0.034 | -0.0219 | No | ||
142 | NLK | 2030010 2450041 | 15071 | -0.040 | -0.0287 | No | ||
143 | RIN1 | 510593 | 15099 | -0.041 | -0.0284 | No | ||
144 | NRF1 | 2650195 | 15109 | -0.042 | -0.0272 | No | ||
145 | BLR1 | 1500300 5420017 | 15171 | -0.044 | -0.0287 | No | ||
146 | ZIC4 | 1500082 | 15173 | -0.044 | -0.0270 | No | ||
147 | ADAM11 | 1050008 3130494 | 15357 | -0.052 | -0.0348 | No | ||
148 | GALR3 | 4850113 | 15434 | -0.056 | -0.0366 | No | ||
149 | SMARCA5 | 6620050 | 15678 | -0.072 | -0.0469 | No | ||
150 | STK3 | 7100427 | 15684 | -0.072 | -0.0442 | No | ||
151 | PKP4 | 3710400 5890097 | 15807 | -0.081 | -0.0475 | No | ||
152 | STRN3 | 1450093 6200685 | 15810 | -0.081 | -0.0443 | No | ||
153 | ACADSB | 520170 | 15851 | -0.084 | -0.0430 | No | ||
154 | CHRNB1 | 1190671 | 15952 | -0.092 | -0.0447 | No | ||
155 | WNT6 | 4570364 | 16119 | -0.106 | -0.0493 | No | ||
156 | MMP11 | 1980619 | 16142 | -0.108 | -0.0461 | No | ||
157 | KCNH2 | 1170451 | 17179 | -0.268 | -0.0914 | No | ||
158 | TMEM24 | 5860039 | 17270 | -0.295 | -0.0842 | No | ||
159 | PLAGL2 | 1770148 | 17310 | -0.305 | -0.0739 | No | ||
160 | TLK2 | 1170161 | 17328 | -0.312 | -0.0621 | No | ||
161 | OSR1 | 1500025 | 17352 | -0.319 | -0.0503 | No | ||
162 | H2AFZ | 1470168 | 17407 | -0.332 | -0.0397 | No | ||
163 | GALNT2 | 2260279 4060239 | 17476 | -0.351 | -0.0291 | No | ||
164 | MAP3K7IP2 | 2340242 | 17841 | -0.481 | -0.0292 | No | ||
165 | ATP1B1 | 3130594 | 17850 | -0.483 | -0.0099 | No | ||
166 | NEDD4L | 6380368 | 17955 | -0.535 | 0.0063 | No | ||
167 | SPOP | 450035 | 18252 | -0.722 | 0.0197 | No |