Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | 0.5158867 |
Normalized Enrichment Score (NES) | 1.3264039 |
Nominal p-value | 0.025723472 |
FDR q-value | 0.8443049 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.0791 | Yes | ||
2 | IGF2 | 6510020 | 26 | 2.564 | 0.1501 | Yes | ||
3 | POLR1D | 70082 450750 6040458 | 37 | 2.354 | 0.2150 | Yes | ||
4 | CKM | 1450524 | 80 | 1.575 | 0.2566 | Yes | ||
5 | HES6 | 540411 6550504 | 96 | 1.504 | 0.2976 | Yes | ||
6 | RANGAP1 | 2320593 6650601 | 130 | 1.244 | 0.3304 | Yes | ||
7 | TTC17 | 2470440 | 243 | 0.967 | 0.3512 | Yes | ||
8 | HEYL | 5860528 | 264 | 0.937 | 0.3762 | Yes | ||
9 | AIG1 | 2450091 | 357 | 0.795 | 0.3933 | Yes | ||
10 | PPOX | 2640678 3850102 | 526 | 0.614 | 0.4013 | Yes | ||
11 | SMAD3 | 6450671 | 532 | 0.607 | 0.4179 | Yes | ||
12 | PTK2B | 4730411 | 591 | 0.567 | 0.4306 | Yes | ||
13 | SELL | 1190500 | 678 | 0.519 | 0.4403 | Yes | ||
14 | ENO3 | 5270136 | 715 | 0.501 | 0.4523 | Yes | ||
15 | TNFSF13 | 2650170 | 776 | 0.479 | 0.4624 | Yes | ||
16 | ELOVL1 | 2450019 4760138 5340685 | 778 | 0.478 | 0.4756 | Yes | ||
17 | GFRA1 | 3610152 | 780 | 0.478 | 0.4889 | Yes | ||
18 | GPD1 | 2480095 | 783 | 0.474 | 0.5020 | Yes | ||
19 | GRB7 | 2100471 | 1133 | 0.366 | 0.4932 | Yes | ||
20 | SASH1 | 4070270 | 1172 | 0.358 | 0.5011 | Yes | ||
21 | HMGA1 | 6580408 | 1226 | 0.349 | 0.5080 | Yes | ||
22 | SLC37A4 | 6400079 | 1257 | 0.344 | 0.5159 | Yes | ||
23 | PSTPIP1 | 3190156 | 1505 | 0.293 | 0.5106 | No | ||
24 | ARID5A | 2450133 | 1827 | 0.242 | 0.5000 | No | ||
25 | CENTB1 | 2120093 | 1941 | 0.223 | 0.5000 | No | ||
26 | NEURL | 5390538 | 1968 | 0.220 | 0.5047 | No | ||
27 | ARHGAP24 | 540278 4540025 | 2083 | 0.205 | 0.5043 | No | ||
28 | IGSF8 | 1580592 | 2130 | 0.198 | 0.5073 | No | ||
29 | STC2 | 4920601 | 2223 | 0.187 | 0.5075 | No | ||
30 | CRELD1 | 2060253 | 2309 | 0.176 | 0.5078 | No | ||
31 | CORO2A | 3840605 6620390 | 2410 | 0.163 | 0.5069 | No | ||
32 | DEF6 | 840593 | 2592 | 0.144 | 0.5011 | No | ||
33 | SIPA1 | 5220687 | 2890 | 0.115 | 0.4882 | No | ||
34 | INVS | 4200632 6620528 | 2913 | 0.113 | 0.4901 | No | ||
35 | IGFBP5 | 2360592 | 3108 | 0.100 | 0.4824 | No | ||
36 | TNFRSF21 | 6380100 | 3175 | 0.096 | 0.4815 | No | ||
37 | ITGB4 | 1740021 3840482 | 3214 | 0.093 | 0.4820 | No | ||
38 | CXCL14 | 840114 6450324 | 3395 | 0.082 | 0.4745 | No | ||
39 | ACTN3 | 3140541 6480598 | 3479 | 0.078 | 0.4722 | No | ||
40 | SYT4 | 5080193 | 3521 | 0.076 | 0.4721 | No | ||
41 | SEMA3F | 5420601 6770731 | 3841 | 0.063 | 0.4565 | No | ||
42 | USP2 | 1190292 1240253 4850035 | 3858 | 0.062 | 0.4574 | No | ||
43 | POFUT1 | 1570458 | 3909 | 0.060 | 0.4563 | No | ||
44 | FGF8 | 6350504 | 3973 | 0.059 | 0.4546 | No | ||
45 | SCG2 | 5670438 130671 | 3977 | 0.058 | 0.4560 | No | ||
46 | DNAJB5 | 2900215 | 4159 | 0.052 | 0.4477 | No | ||
47 | LRP5 | 2100397 3170484 | 4233 | 0.050 | 0.4451 | No | ||
48 | PHACTR3 | 3850435 5900445 | 4313 | 0.048 | 0.4421 | No | ||
49 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4349 | 0.047 | 0.4415 | No | ||
50 | BRUNOL4 | 4490452 5080451 | 4388 | 0.046 | 0.4408 | No | ||
51 | MDGA1 | 1170139 | 4419 | 0.046 | 0.4404 | No | ||
52 | FYN | 2100468 4760520 4850687 | 4488 | 0.044 | 0.4380 | No | ||
53 | GGN | 1410528 4210082 5290170 | 4562 | 0.042 | 0.4352 | No | ||
54 | HOXB7 | 4540706 4610358 | 4650 | 0.040 | 0.4316 | No | ||
55 | PLCB3 | 4670402 | 4747 | 0.038 | 0.4274 | No | ||
56 | PRKAG2 | 2340100 | 4796 | 0.037 | 0.4259 | No | ||
57 | TNNC2 | 3840079 | 5039 | 0.033 | 0.4137 | No | ||
58 | CANX | 4760402 | 5118 | 0.032 | 0.4103 | No | ||
59 | NOL4 | 5050446 5360519 | 5301 | 0.029 | 0.4013 | No | ||
60 | CDH2 | 520435 2450451 2760025 6650477 | 5382 | 0.028 | 0.3977 | No | ||
61 | DNMT3A | 4050068 4810717 | 5636 | 0.025 | 0.3847 | No | ||
62 | DLL1 | 1770377 | 5809 | 0.023 | 0.3760 | No | ||
63 | TEAD4 | 1850239 6380519 | 5980 | 0.021 | 0.3673 | No | ||
64 | FSCN2 | 1230039 | 6126 | 0.020 | 0.3600 | No | ||
65 | POU2F3 | 2030601 | 6150 | 0.019 | 0.3593 | No | ||
66 | CALB1 | 460070 | 6374 | 0.018 | 0.3477 | No | ||
67 | CYP26A1 | 380022 2690600 | 6559 | 0.016 | 0.3382 | No | ||
68 | CHST9 | 4560092 | 6688 | 0.015 | 0.3317 | No | ||
69 | KCNK12 | 4070072 | 6764 | 0.015 | 0.3280 | No | ||
70 | MT3 | 1450537 | 6770 | 0.015 | 0.3281 | No | ||
71 | RASSF2 | 2480079 5720546 | 6856 | 0.014 | 0.3239 | No | ||
72 | PPP1R9B | 3130619 | 6884 | 0.014 | 0.3228 | No | ||
73 | IRX6 | 4590025 | 7206 | 0.012 | 0.3058 | No | ||
74 | GJB2 | 5900609 6200487 | 7294 | 0.012 | 0.3014 | No | ||
75 | CPZ | 70193 | 7334 | 0.011 | 0.2996 | No | ||
76 | SLC24A3 | 5080707 | 7337 | 0.011 | 0.2998 | No | ||
77 | HSD11B2 | 5900053 | 7646 | 0.010 | 0.2834 | No | ||
78 | ANK2 | 6510546 | 7653 | 0.010 | 0.2833 | No | ||
79 | MYOZ3 | 1990138 | 7721 | 0.010 | 0.2799 | No | ||
80 | NR4A1 | 6290161 | 7808 | 0.009 | 0.2755 | No | ||
81 | CALN1 | 3610722 | 7913 | 0.009 | 0.2701 | No | ||
82 | ROBO3 | 6550408 | 7964 | 0.009 | 0.2677 | No | ||
83 | ODC1 | 5670168 | 8053 | 0.008 | 0.2631 | No | ||
84 | RTN4RL2 | 6450609 | 8107 | 0.008 | 0.2605 | No | ||
85 | ALDH1A2 | 2320301 | 8238 | 0.008 | 0.2536 | No | ||
86 | CENTG3 | 2470079 4610092 5050170 | 8338 | 0.007 | 0.2485 | No | ||
87 | GDPD2 | 7000040 | 8392 | 0.007 | 0.2458 | No | ||
88 | CPA4 | 3610100 | 8571 | 0.006 | 0.2363 | No | ||
89 | ZNF205 | 6900022 | 8645 | 0.006 | 0.2325 | No | ||
90 | DOC2A | 6020121 | 8847 | 0.005 | 0.2218 | No | ||
91 | GATA2 | 6590280 | 8958 | 0.005 | 0.2159 | No | ||
92 | DLL3 | 4010093 | 9084 | 0.005 | 0.2093 | No | ||
93 | CORO2B | 2340035 4850390 | 9087 | 0.005 | 0.2093 | No | ||
94 | GPR37 | 2320093 | 9114 | 0.005 | 0.2080 | No | ||
95 | GPM6B | 6220458 | 9134 | 0.005 | 0.2071 | No | ||
96 | NFATC4 | 2470735 | 9463 | 0.004 | 0.1894 | No | ||
97 | ARHGEF12 | 3990195 | 9619 | 0.003 | 0.1811 | No | ||
98 | SFTPC | 3290133 | 9725 | 0.003 | 0.1755 | No | ||
99 | SOST | 1170195 | 9823 | 0.003 | 0.1703 | No | ||
100 | ARVCF | 2190537 | 9960 | 0.002 | 0.1630 | No | ||
101 | MTUS1 | 780348 4920609 | 9978 | 0.002 | 0.1621 | No | ||
102 | CHRND | 840403 2260670 | 10101 | 0.002 | 0.1556 | No | ||
103 | FOXI1 | 3710095 6620195 | 10244 | 0.001 | 0.1479 | No | ||
104 | PPARA | 2060026 | 10473 | 0.001 | 0.1356 | No | ||
105 | KCNB1 | 3610035 | 10551 | 0.000 | 0.1314 | No | ||
106 | CCNL2 | 6520167 | 10655 | 0.000 | 0.1258 | No | ||
107 | PTPRJ | 4010707 | 10981 | -0.001 | 0.1082 | No | ||
108 | BMP6 | 2100128 | 11286 | -0.002 | 0.0918 | No | ||
109 | FGF11 | 840292 | 11319 | -0.002 | 0.0901 | No | ||
110 | SORCS2 | 6350520 | 11375 | -0.002 | 0.0872 | No | ||
111 | NHLH1 | 6100452 | 11423 | -0.002 | 0.0847 | No | ||
112 | SLC12A5 | 1980692 | 11655 | -0.003 | 0.0722 | No | ||
113 | AP1S2 | 780279 4280707 | 11656 | -0.003 | 0.0723 | No | ||
114 | HIF3A | 2630053 2680102 6450364 | 11763 | -0.003 | 0.0666 | No | ||
115 | NBL1 | 2480021 | 11882 | -0.003 | 0.0603 | No | ||
116 | COL4A3 | 5910075 | 12009 | -0.004 | 0.0536 | No | ||
117 | NPEPPS | 2630731 | 12053 | -0.004 | 0.0514 | No | ||
118 | LAMA5 | 2680722 | 12070 | -0.004 | 0.0506 | No | ||
119 | TREX2 | 4920707 | 12081 | -0.004 | 0.0502 | No | ||
120 | GFAP | 2060092 | 12518 | -0.006 | 0.0267 | No | ||
121 | MYH14 | 4010017 | 12550 | -0.006 | 0.0252 | No | ||
122 | MTSS1 | 780435 2370114 | 12551 | -0.006 | 0.0254 | No | ||
123 | UNC13B | 130735 | 12640 | -0.007 | 0.0208 | No | ||
124 | GRIA1 | 1340152 3780750 4920440 | 12645 | -0.007 | 0.0207 | No | ||
125 | TCF2 | 870338 5050632 | 12666 | -0.007 | 0.0198 | No | ||
126 | PCDH15 | 7000438 | 12710 | -0.007 | 0.0177 | No | ||
127 | ANKRD2 | 6590427 | 12826 | -0.007 | 0.0117 | No | ||
128 | WTAP | 4010176 | 12977 | -0.008 | 0.0038 | No | ||
129 | NEGR1 | 1940731 5130170 | 13107 | -0.009 | -0.0030 | No | ||
130 | RAPGEF4 | 6100563 | 13195 | -0.010 | -0.0074 | No | ||
131 | KLHL13 | 6590731 | 13281 | -0.010 | -0.0118 | No | ||
132 | DSCAM | 1780050 2450731 2810438 | 13347 | -0.011 | -0.0150 | No | ||
133 | FUT8 | 1340068 2340056 | 13420 | -0.011 | -0.0186 | No | ||
134 | HR | 2690095 6200300 | 13466 | -0.011 | -0.0207 | No | ||
135 | SOX17 | 5270551 | 13475 | -0.011 | -0.0208 | No | ||
136 | KCNN3 | 6520600 6420138 | 13523 | -0.012 | -0.0230 | No | ||
137 | PIM2 | 840136 5720692 7100577 | 13667 | -0.013 | -0.0304 | No | ||
138 | RAB26 | 5910025 | 13768 | -0.014 | -0.0355 | No | ||
139 | NTRK2 | 6220463 | 13789 | -0.014 | -0.0362 | No | ||
140 | SIM1 | 1770332 | 13826 | -0.015 | -0.0377 | No | ||
141 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 13885 | -0.015 | -0.0404 | No | ||
142 | ITGA6 | 3830129 | 14056 | -0.017 | -0.0492 | No | ||
143 | COL4A4 | 1050541 | 14096 | -0.018 | -0.0508 | No | ||
144 | CHRDL1 | 1580037 6380204 | 14222 | -0.019 | -0.0570 | No | ||
145 | ASB14 | 5860427 | 14376 | -0.022 | -0.0647 | No | ||
146 | SSH2 | 360056 | 14520 | -0.024 | -0.0718 | No | ||
147 | CNNM2 | 2650100 | 14575 | -0.026 | -0.0740 | No | ||
148 | CDH5 | 5340487 | 14577 | -0.026 | -0.0734 | No | ||
149 | EIF2C1 | 6900551 | 14712 | -0.029 | -0.0798 | No | ||
150 | WDR20 | 1240373 | 14754 | -0.030 | -0.0812 | No | ||
151 | TNFAIP1 | 6940593 | 14863 | -0.033 | -0.0861 | No | ||
152 | TRIM23 | 580168 6510672 | 15009 | -0.038 | -0.0930 | No | ||
153 | ADAM12 | 3390132 4070347 | 15020 | -0.038 | -0.0924 | No | ||
154 | RIN1 | 510593 | 15099 | -0.041 | -0.0955 | No | ||
155 | CAMK1D | 1660100 2350309 | 15141 | -0.043 | -0.0965 | No | ||
156 | CAMK2A | 1740333 1940112 4150292 | 15420 | -0.055 | -0.1101 | No | ||
157 | EYA3 | 1580195 6510632 | 15492 | -0.060 | -0.1123 | No | ||
158 | PACSIN3 | 4540369 4540400 5360037 6940129 | 15545 | -0.063 | -0.1133 | No | ||
159 | TGFB3 | 1070041 | 15747 | -0.077 | -0.1221 | No | ||
160 | NTRK3 | 4050687 4070167 4610026 6100484 | 15820 | -0.083 | -0.1237 | No | ||
161 | SORT1 | 1850242 2320632 3870537 | 16113 | -0.106 | -0.1366 | No | ||
162 | WNT6 | 4570364 | 16119 | -0.106 | -0.1339 | No | ||
163 | LNX2 | 3130025 | 16161 | -0.111 | -0.1331 | No | ||
164 | GRB2 | 6650398 | 16274 | -0.122 | -0.1358 | No | ||
165 | HMGN2 | 3140091 | 16644 | -0.172 | -0.1510 | No | ||
166 | NUP88 | 2510044 6760180 | 16929 | -0.219 | -0.1603 | No | ||
167 | SLC23A2 | 6660722 | 17066 | -0.245 | -0.1608 | No | ||
168 | LRP10 | 1580128 | 17145 | -0.262 | -0.1578 | No | ||
169 | PLAGL2 | 1770148 | 17310 | -0.305 | -0.1582 | No | ||
170 | OSR1 | 1500025 | 17352 | -0.319 | -0.1515 | No | ||
171 | CFL1 | 2340735 | 17606 | -0.389 | -0.1544 | No | ||
172 | EGLN1 | 2480180 3120253 6110195 | 17892 | -0.502 | -0.1559 | No | ||
173 | NEDD4L | 6380368 | 17955 | -0.535 | -0.1444 | No | ||
174 | RUNX1 | 3840711 | 18014 | -0.563 | -0.1319 | No | ||
175 | RRAGC | 5910348 | 18037 | -0.577 | -0.1170 | No | ||
176 | MFNG | 1770242 4280348 | 18274 | -0.747 | -0.1090 | No | ||
177 | TPM3 | 670600 3170296 5670167 6650471 | 18614 | -4.583 | 0.0001 | No |