Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$CREBP1_Q2 |
Enrichment Score (ES) | 0.5112599 |
Normalized Enrichment Score (NES) | 1.3055481 |
Nominal p-value | 0.03241491 |
FDR q-value | 0.9531654 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.0812 | Yes | ||
2 | CBX3 | 1780592 3940008 | 72 | 1.645 | 0.1254 | Yes | ||
3 | DSCR1 | 4540048 6220039 | 81 | 1.573 | 0.1700 | Yes | ||
4 | LCMT1 | 2230551 3830497 | 112 | 1.364 | 0.2073 | Yes | ||
5 | DUSP1 | 6860121 | 115 | 1.337 | 0.2454 | Yes | ||
6 | HNRPA2B1 | 1240619 6200161 6200494 6980408 | 152 | 1.154 | 0.2765 | Yes | ||
7 | SLC38A2 | 1470242 3800026 | 180 | 1.086 | 0.3060 | Yes | ||
8 | RUSC1 | 6450093 6980575 | 194 | 1.058 | 0.3356 | Yes | ||
9 | EGR1 | 4610347 | 214 | 1.010 | 0.3634 | Yes | ||
10 | SDHB | 3120398 4780113 3710435 | 225 | 0.996 | 0.3913 | Yes | ||
11 | SPHK2 | 2030487 4120670 4850114 | 301 | 0.894 | 0.4128 | Yes | ||
12 | AGPAT4 | 6040079 | 403 | 0.728 | 0.4282 | Yes | ||
13 | NAPA | 1780537 5720102 | 602 | 0.561 | 0.4335 | Yes | ||
14 | MAP1LC3A | 840519 5570605 | 608 | 0.555 | 0.4491 | Yes | ||
15 | PER1 | 3290315 | 649 | 0.532 | 0.4621 | Yes | ||
16 | PPP1R12C | 580309 4760131 | 719 | 0.500 | 0.4727 | Yes | ||
17 | CEBPB | 2970019 | 760 | 0.485 | 0.4844 | Yes | ||
18 | RCE1 | 1980372 | 884 | 0.440 | 0.4903 | Yes | ||
19 | CCBL1 | 2350082 | 980 | 0.409 | 0.4968 | Yes | ||
20 | RING1 | 4560180 | 1098 | 0.374 | 0.5012 | Yes | ||
21 | SMARCD1 | 3060193 3850184 6400369 | 1240 | 0.347 | 0.5034 | Yes | ||
22 | MRPS18B | 5570086 | 1276 | 0.340 | 0.5113 | Yes | ||
23 | RNF5 | 2760088 | 1631 | 0.271 | 0.4998 | No | ||
24 | PRR3 | 3440112 | 1709 | 0.260 | 0.5031 | No | ||
25 | AGPAT1 | 610056 | 2007 | 0.215 | 0.4931 | No | ||
26 | SPI1 | 1410397 | 2778 | 0.125 | 0.4550 | No | ||
27 | DIABLO | 2360170 | 2788 | 0.124 | 0.4581 | No | ||
28 | BCL2L13 | 3170593 | 2884 | 0.116 | 0.4563 | No | ||
29 | CBX8 | 50671 | 2942 | 0.111 | 0.4563 | No | ||
30 | MLF2 | 1940176 | 3052 | 0.103 | 0.4534 | No | ||
31 | CALML3 | 1980593 | 3349 | 0.085 | 0.4398 | No | ||
32 | MCAM | 5130270 6620577 | 3561 | 0.074 | 0.4304 | No | ||
33 | EGR3 | 6940128 | 3572 | 0.073 | 0.4320 | No | ||
34 | NR4A2 | 60273 | 3577 | 0.073 | 0.4339 | No | ||
35 | FOS | 1850315 | 3778 | 0.065 | 0.4249 | No | ||
36 | FGF13 | 630575 1570440 5360121 | 3845 | 0.063 | 0.4231 | No | ||
37 | USP2 | 1190292 1240253 4850035 | 3858 | 0.062 | 0.4242 | No | ||
38 | NR2E1 | 4730288 | 3876 | 0.061 | 0.4251 | No | ||
39 | SCG2 | 5670438 130671 | 3977 | 0.058 | 0.4213 | No | ||
40 | BIN1 | 5420348 5670500 | 4398 | 0.046 | 0.3999 | No | ||
41 | LMO4 | 3800746 | 4468 | 0.045 | 0.3974 | No | ||
42 | UBAP1 | 4280059 | 4549 | 0.043 | 0.3943 | No | ||
43 | THRAP3 | 6180309 | 4835 | 0.037 | 0.3799 | No | ||
44 | HOXC10 | 5360170 | 4849 | 0.036 | 0.3803 | No | ||
45 | ING3 | 110438 2060390 | 5000 | 0.034 | 0.3731 | No | ||
46 | SNAP25 | 360520 | 5174 | 0.031 | 0.3646 | No | ||
47 | NOL4 | 5050446 5360519 | 5301 | 0.029 | 0.3586 | No | ||
48 | SLC6A4 | 2230372 | 5370 | 0.028 | 0.3557 | No | ||
49 | DDX51 | 5550044 6350270 6590750 | 5420 | 0.027 | 0.3539 | No | ||
50 | GPR3 | 2970452 | 5430 | 0.027 | 0.3542 | No | ||
51 | EPHA2 | 5890056 | 5484 | 0.027 | 0.3520 | No | ||
52 | PDLIM3 | 1410095 | 5710 | 0.024 | 0.3405 | No | ||
53 | HHEX | 2340575 | 5757 | 0.023 | 0.3387 | No | ||
54 | CD2AP | 1940369 | 5874 | 0.022 | 0.3331 | No | ||
55 | HOXA3 | 3610632 6020358 | 6022 | 0.021 | 0.3257 | No | ||
56 | EEF2 | 1050369 4670035 5890598 | 6055 | 0.020 | 0.3245 | No | ||
57 | PPP2R2A | 2900014 5700575 | 6127 | 0.020 | 0.3212 | No | ||
58 | DMD | 1740041 3990332 | 6288 | 0.018 | 0.3131 | No | ||
59 | AHI1 | 460520 | 6304 | 0.018 | 0.3128 | No | ||
60 | TRIB1 | 2320435 | 6327 | 0.018 | 0.3121 | No | ||
61 | MSX2 | 1570022 | 6380 | 0.017 | 0.3098 | No | ||
62 | SMAD1 | 630537 1850333 | 6399 | 0.017 | 0.3093 | No | ||
63 | GRM3 | 4540242 | 6539 | 0.016 | 0.3023 | No | ||
64 | SYNGR3 | 4590576 | 6619 | 0.016 | 0.2984 | No | ||
65 | NPTX1 | 3710736 | 6930 | 0.014 | 0.2820 | No | ||
66 | BCL11A | 6860369 | 6996 | 0.013 | 0.2789 | No | ||
67 | ATP6V0C | 1780609 | 7091 | 0.013 | 0.2742 | No | ||
68 | IRX6 | 4590025 | 7206 | 0.012 | 0.2683 | No | ||
69 | HHIP | 6940438 | 7231 | 0.012 | 0.2674 | No | ||
70 | PAFAH1B1 | 4230333 6420121 6450066 | 7240 | 0.012 | 0.2673 | No | ||
71 | ABR | 610079 1170609 3610195 5670050 | 7306 | 0.012 | 0.2641 | No | ||
72 | ZBTB11 | 6520092 | 7336 | 0.011 | 0.2628 | No | ||
73 | FLRT3 | 70685 2760497 6040519 | 7341 | 0.011 | 0.2629 | No | ||
74 | PPM2C | 3360209 | 7397 | 0.011 | 0.2603 | No | ||
75 | RET | 3850746 | 7453 | 0.011 | 0.2576 | No | ||
76 | NEUROD6 | 4670731 | 7501 | 0.011 | 0.2554 | No | ||
77 | UCN | 6620338 | 7554 | 0.010 | 0.2528 | No | ||
78 | MESDC1 | 2030019 | 7568 | 0.010 | 0.2524 | No | ||
79 | SCAMP5 | 5550368 6290021 | 8007 | 0.008 | 0.2289 | No | ||
80 | SNF1LK | 6110403 | 8069 | 0.008 | 0.2259 | No | ||
81 | PCSK1 | 2350148 | 8127 | 0.008 | 0.2230 | No | ||
82 | PNRC1 | 360025 | 8178 | 0.008 | 0.2205 | No | ||
83 | DACT1 | 1500050 | 8500 | 0.007 | 0.2033 | No | ||
84 | ERF | 110551 1770278 | 8622 | 0.006 | 0.1969 | No | ||
85 | MAP3K13 | 3190017 | 9046 | 0.005 | 0.1742 | No | ||
86 | UBQLN2 | 430397 1170594 4070121 | 9126 | 0.005 | 0.1700 | No | ||
87 | GPM6B | 6220458 | 9134 | 0.005 | 0.1698 | No | ||
88 | DAAM2 | 1400358 7650669 | 9276 | 0.004 | 0.1622 | No | ||
89 | EGR4 | 3120750 | 9437 | 0.004 | 0.1537 | No | ||
90 | PNMA3 | 3170309 | 9554 | 0.003 | 0.1475 | No | ||
91 | NF1 | 6980433 | 9709 | 0.003 | 0.1392 | No | ||
92 | MAFF | 4850577 5720286 | 9731 | 0.003 | 0.1382 | No | ||
93 | SUV39H2 | 1450672 6370242 | 9814 | 0.003 | 0.1338 | No | ||
94 | CCND2 | 5340167 | 9902 | 0.002 | 0.1292 | No | ||
95 | CLDN7 | 1190301 | 10041 | 0.002 | 0.1217 | No | ||
96 | PEG3 | 3710020 | 10278 | 0.001 | 0.1090 | No | ||
97 | ELL2 | 6420091 | 10575 | 0.000 | 0.0930 | No | ||
98 | KCNA5 | 5270750 | 10637 | 0.000 | 0.0897 | No | ||
99 | KCNK1 | 1050068 | 10696 | 0.000 | 0.0865 | No | ||
100 | TACR1 | 70358 3840411 | 10741 | -0.000 | 0.0841 | No | ||
101 | SLC6A5 | 870121 | 10790 | -0.000 | 0.0815 | No | ||
102 | PTPRU | 3170180 | 11192 | -0.001 | 0.0599 | No | ||
103 | PITX2 | 870537 2690139 | 11222 | -0.001 | 0.0583 | No | ||
104 | CRH | 3710301 | 11641 | -0.003 | 0.0358 | No | ||
105 | KCTD8 | 6660593 | 11794 | -0.003 | 0.0276 | No | ||
106 | FOXD3 | 6550156 | 12005 | -0.004 | 0.0163 | No | ||
107 | NAP1L2 | 130047 | 12094 | -0.004 | 0.0117 | No | ||
108 | GEM | 5290082 | 12141 | -0.004 | 0.0093 | No | ||
109 | HS6ST2 | 520133 5550603 | 12293 | -0.005 | 0.0013 | No | ||
110 | SLC18A2 | 6420541 | 12297 | -0.005 | 0.0013 | No | ||
111 | IRX4 | 1980102 | 12506 | -0.006 | -0.0098 | No | ||
112 | CREM | 840156 6380438 6660041 6660168 | 12788 | -0.007 | -0.0248 | No | ||
113 | FOSB | 1940142 | 13004 | -0.008 | -0.0363 | No | ||
114 | HOXD8 | 3710156 | 13049 | -0.009 | -0.0384 | No | ||
115 | SEMA4C | 1980315 | 13389 | -0.011 | -0.0564 | No | ||
116 | EGR2 | 3800403 | 13422 | -0.011 | -0.0579 | No | ||
117 | FLT1 | 3830167 4920438 | 13493 | -0.012 | -0.0613 | No | ||
118 | GNG4 | 2630600 | 13820 | -0.015 | -0.0786 | No | ||
119 | TH | 2100056 | 13838 | -0.015 | -0.0791 | No | ||
120 | PPARGC1A | 4670040 | 13963 | -0.016 | -0.0853 | No | ||
121 | RPL41 | 6940112 | 14026 | -0.017 | -0.0882 | No | ||
122 | BAT5 | 5720687 | 14269 | -0.020 | -0.1007 | No | ||
123 | WNT10A | 2100706 | 14302 | -0.021 | -0.1019 | No | ||
124 | NR4A3 | 2900021 5860095 5910039 | 14482 | -0.024 | -0.1109 | No | ||
125 | SLC25A25 | 1230605 | 14513 | -0.024 | -0.1118 | No | ||
126 | ICA1 | 3830059 | 14643 | -0.027 | -0.1180 | No | ||
127 | GTF2A1 | 4120138 4920524 5390110 1230397 | 14887 | -0.034 | -0.1302 | No | ||
128 | RAB6A | 3840463 4780731 | 14953 | -0.035 | -0.1328 | No | ||
129 | CHGB | 1980053 | 15088 | -0.041 | -0.1388 | No | ||
130 | TGIF2 | 3840364 4050520 | 15134 | -0.043 | -0.1401 | No | ||
131 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 15327 | -0.050 | -0.1490 | No | ||
132 | THRA | 6770341 110164 1990600 | 15479 | -0.059 | -0.1555 | No | ||
133 | RAI1 | 110377 5340670 | 15493 | -0.060 | -0.1545 | No | ||
134 | RANBP2 | 4280338 | 15730 | -0.075 | -0.1651 | No | ||
135 | PDE4D | 2470528 6660014 | 15736 | -0.076 | -0.1632 | No | ||
136 | YME1L1 | 2360102 2510520 2650451 | 15772 | -0.079 | -0.1629 | No | ||
137 | TRAP1 | 6040168 | 15911 | -0.089 | -0.1678 | No | ||
138 | ADAM9 | 3360411 | 16007 | -0.096 | -0.1702 | No | ||
139 | ELOVL5 | 3800170 | 16156 | -0.110 | -0.1751 | No | ||
140 | CALM2 | 6620463 | 16673 | -0.176 | -0.1980 | No | ||
141 | NCALD | 730176 | 16677 | -0.177 | -0.1931 | No | ||
142 | IKBKB | 6840072 | 16922 | -0.218 | -0.2001 | No | ||
143 | DLST | 2320722 | 16936 | -0.221 | -0.1945 | No | ||
144 | STAT3 | 460040 3710341 | 16973 | -0.227 | -0.1900 | No | ||
145 | PPM1A | 1170301 5900273 | 17340 | -0.317 | -0.2007 | No | ||
146 | OSR1 | 1500025 | 17352 | -0.319 | -0.1922 | No | ||
147 | ATP10D | 4850139 | 17424 | -0.336 | -0.1865 | No | ||
148 | SENP2 | 4540452 | 17642 | -0.407 | -0.1866 | No | ||
149 | DDX3X | 2190020 | 17682 | -0.421 | -0.1767 | No | ||
150 | ELAVL1 | 4730497 | 17796 | -0.464 | -0.1695 | No | ||
151 | KLF13 | 4670563 | 17991 | -0.551 | -0.1643 | No | ||
152 | WBP5 | 7050563 | 18050 | -0.585 | -0.1507 | No | ||
153 | TPM4 | 2100059 3850072 4920162 | 18079 | -0.604 | -0.1350 | No | ||
154 | OSBPL9 | 2570373 | 18156 | -0.647 | -0.1206 | No | ||
155 | DHX36 | 2470465 | 18180 | -0.659 | -0.1030 | No | ||
156 | MBNL1 | 2640762 7100048 | 18381 | -0.865 | -0.0891 | No | ||
157 | SLC31A1 | 4590161 6940154 | 18492 | -1.090 | -0.0639 | No | ||
158 | SFRS1 | 2360440 | 18508 | -1.134 | -0.0323 | No | ||
159 | PPP1R10 | 110136 3170725 3610484 | 18539 | -1.334 | 0.0042 | No |