Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$BACH1_01 |
Enrichment Score (ES) | 0.49377602 |
Normalized Enrichment Score (NES) | 1.2761441 |
Nominal p-value | 0.044025157 |
FDR q-value | 0.91188514 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SFRS2 | 50707 380593 | 7 | 4.052 | 0.1087 | Yes | ||
2 | NCDN | 50040 1980739 3520603 | 77 | 1.599 | 0.1480 | Yes | ||
3 | ENO1 | 5340128 | 90 | 1.526 | 0.1885 | Yes | ||
4 | NDRG2 | 450403 | 104 | 1.446 | 0.2267 | Yes | ||
5 | PADI4 | 1740075 4810441 | 204 | 1.039 | 0.2493 | Yes | ||
6 | EPHB2 | 1090288 1410377 2100541 | 207 | 1.036 | 0.2771 | Yes | ||
7 | CHST1 | 50601 | 229 | 0.989 | 0.3026 | Yes | ||
8 | UBE2E3 | 2030347 3840471 | 269 | 0.933 | 0.3256 | Yes | ||
9 | ECM1 | 940068 5390309 | 352 | 0.800 | 0.3427 | Yes | ||
10 | S100A10 | 6350010 | 414 | 0.712 | 0.3586 | Yes | ||
11 | LMNA | 520471 1500075 3190167 4210020 | 450 | 0.670 | 0.3747 | Yes | ||
12 | TAGLN2 | 4560121 | 639 | 0.534 | 0.3789 | Yes | ||
13 | ALDOA | 6290672 | 779 | 0.478 | 0.3842 | Yes | ||
14 | ALS2CR2 | 6450128 7100092 | 809 | 0.464 | 0.3951 | Yes | ||
15 | GNGT2 | 540176 | 862 | 0.447 | 0.4043 | Yes | ||
16 | SGK | 1400131 2480056 | 946 | 0.418 | 0.4111 | Yes | ||
17 | SQSTM1 | 6550056 | 1025 | 0.393 | 0.4174 | Yes | ||
18 | ITPKC | 5420021 | 1128 | 0.366 | 0.4217 | Yes | ||
19 | HMGA1 | 6580408 | 1226 | 0.349 | 0.4259 | Yes | ||
20 | GABARAPL1 | 2810458 | 1295 | 0.336 | 0.4312 | Yes | ||
21 | BAG2 | 2900324 | 1373 | 0.320 | 0.4357 | Yes | ||
22 | MAST2 | 6200348 | 1424 | 0.308 | 0.4412 | Yes | ||
23 | TRAPPC3 | 2030176 6020609 6590373 6760019 | 1724 | 0.257 | 0.4319 | Yes | ||
24 | AP2A2 | 130082 | 1725 | 0.257 | 0.4389 | Yes | ||
25 | ADCK4 | 1660180 | 1795 | 0.247 | 0.4418 | Yes | ||
26 | HSPB8 | 540563 | 1848 | 0.238 | 0.4454 | Yes | ||
27 | SNPH | 2680484 | 1876 | 0.234 | 0.4502 | Yes | ||
28 | ROM1 | 3130685 | 1921 | 0.228 | 0.4539 | Yes | ||
29 | EDG5 | 2640300 | 1995 | 0.218 | 0.4558 | Yes | ||
30 | GPX1 | 4150093 | 2029 | 0.212 | 0.4597 | Yes | ||
31 | RPS6KA4 | 2190524 | 2037 | 0.211 | 0.4650 | Yes | ||
32 | EMP3 | 1500722 1570039 | 2042 | 0.210 | 0.4705 | Yes | ||
33 | ABCD1 | 5670373 | 2091 | 0.203 | 0.4734 | Yes | ||
34 | MNT | 4920575 | 2116 | 0.200 | 0.4774 | Yes | ||
35 | TNFRSF12A | 4810253 | 2168 | 0.193 | 0.4799 | Yes | ||
36 | LTB4R2 | 1990746 | 2285 | 0.179 | 0.4784 | Yes | ||
37 | ABCA2 | 5050039 | 2296 | 0.177 | 0.4826 | Yes | ||
38 | SCRN1 | 6040025 6580019 | 2302 | 0.177 | 0.4871 | Yes | ||
39 | CAMKK1 | 6370324 | 2357 | 0.169 | 0.4887 | Yes | ||
40 | AXUD1 | 1230053 | 2403 | 0.164 | 0.4907 | Yes | ||
41 | HDAC3 | 4060072 | 2427 | 0.161 | 0.4938 | Yes | ||
42 | PIM1 | 630047 | 2596 | 0.143 | 0.4885 | No | ||
43 | TUBB4 | 5310681 | 2695 | 0.132 | 0.4868 | No | ||
44 | PSME4 | 380348 1770131 | 2759 | 0.127 | 0.4867 | No | ||
45 | SEC24D | 3060279 | 3041 | 0.104 | 0.4743 | No | ||
46 | WASF2 | 4850592 | 3142 | 0.098 | 0.4715 | No | ||
47 | ITGB4 | 1740021 3840482 | 3214 | 0.093 | 0.4702 | No | ||
48 | CFL2 | 380239 6200368 | 3215 | 0.093 | 0.4727 | No | ||
49 | CDH23 | 4250242 5290397 6550397 | 3237 | 0.091 | 0.4740 | No | ||
50 | ADRA1A | 1230446 2260390 | 3302 | 0.088 | 0.4729 | No | ||
51 | SLC26A9 | 3440722 5340088 7510093 | 3412 | 0.081 | 0.4691 | No | ||
52 | ELL | 3520731 | 3439 | 0.080 | 0.4699 | No | ||
53 | BDKRB1 | 730592 | 3541 | 0.075 | 0.4664 | No | ||
54 | ACPP | 2470152 1780593 2690524 | 3547 | 0.075 | 0.4682 | No | ||
55 | SERTAD1 | 2680332 | 3635 | 0.071 | 0.4653 | No | ||
56 | EIF4E | 1580403 70133 6380215 | 3677 | 0.069 | 0.4650 | No | ||
57 | COL7A1 | 1230168 2190072 | 3924 | 0.060 | 0.4532 | No | ||
58 | DDIT3 | 780373 | 3950 | 0.059 | 0.4535 | No | ||
59 | PRX | 2260400 4200347 | 4010 | 0.057 | 0.4518 | No | ||
60 | DCTN2 | 540471 3780717 | 4018 | 0.057 | 0.4529 | No | ||
61 | NRAS | 6900577 | 4135 | 0.053 | 0.4481 | No | ||
62 | NR1D1 | 2360471 770746 6590204 | 4145 | 0.053 | 0.4490 | No | ||
63 | TRIM47 | 5080717 | 4311 | 0.048 | 0.4414 | No | ||
64 | CSMD3 | 1660427 1940687 | 4325 | 0.047 | 0.4419 | No | ||
65 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4349 | 0.047 | 0.4419 | No | ||
66 | RB1CC1 | 510494 7100072 | 4445 | 0.045 | 0.4380 | No | ||
67 | MRGPRF | 4780746 | 4462 | 0.045 | 0.4383 | No | ||
68 | SYN1 | 4920301 7050440 | 4794 | 0.037 | 0.4214 | No | ||
69 | PKP3 | 3710048 | 4836 | 0.037 | 0.4202 | No | ||
70 | SYNGR1 | 5130452 6650056 | 4853 | 0.036 | 0.4203 | No | ||
71 | TREX1 | 3450040 7100692 | 5057 | 0.033 | 0.4101 | No | ||
72 | UBE2C | 6130017 | 5158 | 0.031 | 0.4056 | No | ||
73 | CSF3 | 2230193 6660707 | 5195 | 0.031 | 0.4044 | No | ||
74 | PROK2 | 540538 | 5258 | 0.030 | 0.4019 | No | ||
75 | F2RL2 | 6110736 | 5380 | 0.028 | 0.3960 | No | ||
76 | GPR3 | 2970452 | 5430 | 0.027 | 0.3941 | No | ||
77 | DYSF | 4670411 | 5530 | 0.026 | 0.3895 | No | ||
78 | LAMC2 | 450692 2680041 4200059 4670148 | 5902 | 0.022 | 0.3699 | No | ||
79 | EEF1A2 | 2260162 5290086 | 5913 | 0.022 | 0.3699 | No | ||
80 | ELAVL2 | 360181 | 5914 | 0.022 | 0.3705 | No | ||
81 | GKN1 | 5420091 | 5986 | 0.021 | 0.3672 | No | ||
82 | MARK1 | 450484 | 6011 | 0.021 | 0.3665 | No | ||
83 | FOXN1 | 4730075 | 6134 | 0.020 | 0.3604 | No | ||
84 | NEK6 | 3360687 | 6249 | 0.019 | 0.3547 | No | ||
85 | TRIB1 | 2320435 | 6327 | 0.018 | 0.3510 | No | ||
86 | DNAJC5B | 60368 | 6367 | 0.018 | 0.3494 | No | ||
87 | PTPRR | 130121 3990273 | 6416 | 0.017 | 0.3472 | No | ||
88 | HS3ST3B1 | 380040 | 6504 | 0.016 | 0.3430 | No | ||
89 | VIT | 6620301 | 6531 | 0.016 | 0.3420 | No | ||
90 | ELK3 | 460377 1400762 3710497 | 6616 | 0.016 | 0.3378 | No | ||
91 | PPP1R9B | 3130619 | 6884 | 0.014 | 0.3237 | No | ||
92 | DIRAS1 | 2640270 | 6923 | 0.014 | 0.3220 | No | ||
93 | PADI3 | 6520072 | 6956 | 0.013 | 0.3207 | No | ||
94 | BTK | 3130044 | 7004 | 0.013 | 0.3185 | No | ||
95 | HOXB3 | 520292 | 7007 | 0.013 | 0.3187 | No | ||
96 | TGM3 | 840576 | 7101 | 0.013 | 0.3140 | No | ||
97 | FADS3 | 3120079 | 7553 | 0.010 | 0.2898 | No | ||
98 | SHC3 | 2690398 | 7559 | 0.010 | 0.2898 | No | ||
99 | GDNF | 4050487 5720739 | 7598 | 0.010 | 0.2880 | No | ||
100 | FOXA1 | 3710609 | 7746 | 0.009 | 0.2803 | No | ||
101 | CAPN6 | 1740168 | 7773 | 0.009 | 0.2791 | No | ||
102 | SLC26A1 | 2190142 | 7918 | 0.009 | 0.2716 | No | ||
103 | MYBPH | 2190711 | 8041 | 0.008 | 0.2652 | No | ||
104 | LPP | 1660541 | 8169 | 0.008 | 0.2585 | No | ||
105 | DSC2 | 840484 | 8202 | 0.008 | 0.2570 | No | ||
106 | NTN4 | 6940398 | 8217 | 0.008 | 0.2564 | No | ||
107 | TLL1 | 2680315 | 8219 | 0.008 | 0.2566 | No | ||
108 | BNIP3 | 3140270 | 8305 | 0.007 | 0.2521 | No | ||
109 | BMP2 | 6620687 | 8306 | 0.007 | 0.2523 | No | ||
110 | LRRTM3 | 4210021 | 8321 | 0.007 | 0.2518 | No | ||
111 | MAMDC2 | 430471 | 8447 | 0.007 | 0.2452 | No | ||
112 | IBRDC2 | 5130041 | 8456 | 0.007 | 0.2449 | No | ||
113 | OSBP | 5390471 | 8579 | 0.006 | 0.2385 | No | ||
114 | EIF3S1 | 6130368 6770044 | 8891 | 0.005 | 0.2217 | No | ||
115 | SH3RF2 | 6200600 | 8960 | 0.005 | 0.2182 | No | ||
116 | SYP | 2690168 | 9428 | 0.004 | 0.1929 | No | ||
117 | LY6G6C | 6020673 | 9535 | 0.003 | 0.1873 | No | ||
118 | GPR56 | 1190494 | 9699 | 0.003 | 0.1785 | No | ||
119 | MYB | 1660494 5860451 6130706 | 9777 | 0.003 | 0.1744 | No | ||
120 | FABP4 | 5050114 | 9941 | 0.002 | 0.1656 | No | ||
121 | PHLDA2 | 4810494 | 10046 | 0.002 | 0.1600 | No | ||
122 | SYT2 | 60609 | 10459 | 0.001 | 0.1377 | No | ||
123 | SLC24A4 | 2100487 | 10526 | 0.001 | 0.1341 | No | ||
124 | MMP3 | 2650368 2970056 | 10537 | 0.001 | 0.1336 | No | ||
125 | IL1RN | 2370333 | 10640 | 0.000 | 0.1281 | No | ||
126 | AKT3 | 1580270 3290278 | 10642 | 0.000 | 0.1280 | No | ||
127 | SLC6A5 | 870121 | 10790 | -0.000 | 0.1200 | No | ||
128 | RGS2 | 1090736 | 10837 | -0.000 | 0.1175 | No | ||
129 | NR1I3 | 50026 1240673 | 11021 | -0.001 | 0.1076 | No | ||
130 | AKAP1 | 110148 1740735 2260019 7000563 | 11590 | -0.003 | 0.0769 | No | ||
131 | FGF12 | 1740446 2360037 | 11670 | -0.003 | 0.0727 | No | ||
132 | FAP | 4560019 | 12032 | -0.004 | 0.0532 | No | ||
133 | GNAI1 | 4560390 | 12252 | -0.005 | 0.0414 | No | ||
134 | ADAMTSL1 | 2970092 | 12412 | -0.005 | 0.0330 | No | ||
135 | IL11 | 1740398 | 12421 | -0.006 | 0.0327 | No | ||
136 | GFAP | 2060092 | 12518 | -0.006 | 0.0276 | No | ||
137 | MYH14 | 4010017 | 12550 | -0.006 | 0.0261 | No | ||
138 | GRIA1 | 1340152 3780750 4920440 | 12645 | -0.007 | 0.0212 | No | ||
139 | SNCB | 3360133 | 12674 | -0.007 | 0.0198 | No | ||
140 | UCN2 | 4590372 | 12737 | -0.007 | 0.0167 | No | ||
141 | P2RXL1 | 4730390 5220446 | 12818 | -0.007 | 0.0125 | No | ||
142 | TAC1 | 7000195 380706 | 12833 | -0.007 | 0.0120 | No | ||
143 | KCNA2 | 5080403 | 13291 | -0.010 | -0.0126 | No | ||
144 | CDKN1A | 4050088 6400706 | 13471 | -0.011 | -0.0220 | No | ||
145 | PSMD11 | 2340538 6510053 | 13573 | -0.012 | -0.0271 | No | ||
146 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | -0.0380 | No | ||
147 | SPARC | 1690086 | 13824 | -0.015 | -0.0399 | No | ||
148 | LRRC15 | 3940609 | 14092 | -0.018 | -0.0539 | No | ||
149 | TNXB | 630592 3830020 5360497 7000673 | 14176 | -0.019 | -0.0579 | No | ||
150 | CAPN12 | 2100050 | 14239 | -0.020 | -0.0607 | No | ||
151 | ENO2 | 2320068 | 14423 | -0.023 | -0.0700 | No | ||
152 | RPS20 | 1740092 | 14489 | -0.024 | -0.0729 | No | ||
153 | HCN3 | 3940438 6840750 | 14504 | -0.024 | -0.0730 | No | ||
154 | SSH2 | 360056 | 14520 | -0.024 | -0.0732 | No | ||
155 | TNRC15 | 6760746 | 14709 | -0.029 | -0.0826 | No | ||
156 | LAMA3 | 1190131 5290239 | 14790 | -0.031 | -0.0861 | No | ||
157 | TRAF3 | 5690647 | 14967 | -0.036 | -0.0947 | No | ||
158 | NLK | 2030010 2450041 | 15071 | -0.040 | -0.0992 | No | ||
159 | RIN1 | 510593 | 15099 | -0.041 | -0.0996 | No | ||
160 | RPL23A | 1450403 | 15101 | -0.042 | -0.0985 | No | ||
161 | LAMC1 | 4730025 | 15203 | -0.045 | -0.1028 | No | ||
162 | EN1 | 5360168 7050025 | 15637 | -0.069 | -0.1244 | No | ||
163 | DYRK1A | 3190181 | 15694 | -0.073 | -0.1255 | No | ||
164 | BCL9L | 6940053 | 15926 | -0.090 | -0.1356 | No | ||
165 | GTPBP2 | 2760750 | 16140 | -0.108 | -0.1442 | No | ||
166 | ACADVL | 6040403 | 16284 | -0.123 | -0.1487 | No | ||
167 | ABI3 | 1740563 | 16509 | -0.151 | -0.1568 | No | ||
168 | APOBEC1 | 4610022 | 16546 | -0.157 | -0.1545 | No | ||
169 | ABHD4 | 6760450 | 16760 | -0.188 | -0.1610 | No | ||
170 | PSMD4 | 430068 | 16899 | -0.215 | -0.1627 | No | ||
171 | MPV17 | 1190133 4070427 4570577 | 16939 | -0.221 | -0.1589 | No | ||
172 | GTF2B | 6860685 | 17024 | -0.236 | -0.1571 | No | ||
173 | LAMB3 | 7100301 | 17228 | -0.282 | -0.1605 | No | ||
174 | MECP2 | 1940450 | 17253 | -0.290 | -0.1540 | No | ||
175 | RAB34 | 770411 | 17286 | -0.299 | -0.1477 | No | ||
176 | RBBP7 | 430113 450450 2370309 | 17510 | -0.357 | -0.1502 | No | ||
177 | RAB3D | 4210253 | 17519 | -0.359 | -0.1409 | No | ||
178 | PSMD12 | 730044 | 17531 | -0.365 | -0.1317 | No | ||
179 | EIF4G1 | 4070446 | 17816 | -0.472 | -0.1344 | No | ||
180 | ATP1B1 | 3130594 | 17850 | -0.483 | -0.1232 | No | ||
181 | TRIM8 | 6130441 | 17883 | -0.496 | -0.1116 | No | ||
182 | EEF1A1 | 1980193 1990195 4670735 | 17923 | -0.517 | -0.0998 | No | ||
183 | PSMD7 | 2030619 6220594 | 18080 | -0.604 | -0.0920 | No | ||
184 | LUC7L | 6040156 6110411 | 18088 | -0.608 | -0.0760 | No | ||
185 | RTN4 | 50725 630647 870097 870184 | 18214 | -0.685 | -0.0643 | No | ||
186 | PPP2CA | 3990113 | 18255 | -0.725 | -0.0470 | No | ||
187 | H3F3B | 1410300 | 18257 | -0.727 | -0.0275 | No | ||
188 | SRPK2 | 6380341 | 18312 | -0.780 | -0.0094 | No | ||
189 | BRD2 | 1450300 5340484 6100605 | 18444 | -0.960 | 0.0093 | No |