Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$AREB6_03 |
Enrichment Score (ES) | 0.52618706 |
Normalized Enrichment Score (NES) | 1.3515016 |
Nominal p-value | 0.030351438 |
FDR q-value | 0.7186259 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | FAF1 | 2450717 2510121 4730156 | 8 | 3.763 | 0.1386 | Yes | ||
2 | IGF2 | 6510020 | 26 | 2.564 | 0.2324 | Yes | ||
3 | SSBP3 | 870717 1050377 7040551 | 92 | 1.522 | 0.2852 | Yes | ||
4 | DNMT3B | 2320138 4070059 | 94 | 1.518 | 0.3412 | Yes | ||
5 | DGKZ | 3460041 6400129 | 133 | 1.227 | 0.3845 | Yes | ||
6 | EXTL3 | 540309 3130215 5860500 | 282 | 0.918 | 0.4104 | Yes | ||
7 | FXC1 | 3710053 4060575 | 573 | 0.580 | 0.4161 | Yes | ||
8 | DGKA | 5720152 5890328 | 578 | 0.577 | 0.4372 | Yes | ||
9 | GNA12 | 1230301 | 737 | 0.495 | 0.4469 | Yes | ||
10 | ARFIP2 | 1850301 4670180 | 751 | 0.489 | 0.4643 | Yes | ||
11 | GPD1 | 2480095 | 783 | 0.474 | 0.4801 | Yes | ||
12 | ALS2CR2 | 6450128 7100092 | 809 | 0.464 | 0.4959 | Yes | ||
13 | PNKP | 4610685 5720605 | 859 | 0.447 | 0.5098 | Yes | ||
14 | REPIN1 | 6110400 | 1227 | 0.349 | 0.5028 | Yes | ||
15 | MRPL14 | 2370168 | 1559 | 0.284 | 0.4953 | Yes | ||
16 | CUEDC1 | 1660463 | 1591 | 0.278 | 0.5039 | Yes | ||
17 | PARD6A | 4120170 | 1600 | 0.276 | 0.5137 | Yes | ||
18 | SERF2 | 5720010 | 1962 | 0.220 | 0.5023 | Yes | ||
19 | TNNI1 | 3710040 | 2052 | 0.209 | 0.5052 | Yes | ||
20 | EHD1 | 3840731 | 2232 | 0.186 | 0.5024 | Yes | ||
21 | VAT1 | 1050040 | 2297 | 0.177 | 0.5054 | Yes | ||
22 | CRELD1 | 2060253 | 2309 | 0.176 | 0.5113 | Yes | ||
23 | HDAC3 | 4060072 | 2427 | 0.161 | 0.5109 | Yes | ||
24 | E2F1 | 5360093 | 2480 | 0.155 | 0.5138 | Yes | ||
25 | FGR | 3780047 | 2521 | 0.150 | 0.5172 | Yes | ||
26 | CRSP7 | 4230408 | 2561 | 0.147 | 0.5205 | Yes | ||
27 | TEC | 1400576 | 2591 | 0.144 | 0.5243 | Yes | ||
28 | VGLL4 | 6860463 | 2650 | 0.137 | 0.5262 | Yes | ||
29 | CBX8 | 50671 | 2942 | 0.111 | 0.5145 | No | ||
30 | ITGB4 | 1740021 3840482 | 3214 | 0.093 | 0.5033 | No | ||
31 | PHF1 | 4010577 6420053 | 3283 | 0.089 | 0.5029 | No | ||
32 | NUMBL | 6130360 6200333 | 3376 | 0.083 | 0.5010 | No | ||
33 | RGMA | 2450711 | 3465 | 0.079 | 0.4991 | No | ||
34 | ACCN4 | 6380551 | 3573 | 0.073 | 0.4960 | No | ||
35 | NR4A2 | 60273 | 3577 | 0.073 | 0.4985 | No | ||
36 | ALX3 | 50497 | 3654 | 0.070 | 0.4970 | No | ||
37 | APP | 2510053 | 3706 | 0.068 | 0.4967 | No | ||
38 | SEMA3F | 5420601 6770731 | 3841 | 0.063 | 0.4918 | No | ||
39 | POFUT1 | 1570458 | 3909 | 0.060 | 0.4904 | No | ||
40 | PDE11A | 2190215 | 3923 | 0.060 | 0.4919 | No | ||
41 | FGF8 | 6350504 | 3973 | 0.059 | 0.4914 | No | ||
42 | KIF1C | 2480484 | 4088 | 0.055 | 0.4872 | No | ||
43 | IRF6 | 840241 2640139 4050373 6840471 | 4089 | 0.055 | 0.4893 | No | ||
44 | HNF4A | 6620440 | 4142 | 0.053 | 0.4884 | No | ||
45 | LRP5 | 2100397 3170484 | 4233 | 0.050 | 0.4854 | No | ||
46 | ELL3 | 1770484 | 4241 | 0.050 | 0.4868 | No | ||
47 | KREMEN2 | 110025 | 4284 | 0.049 | 0.4864 | No | ||
48 | PHACTR3 | 3850435 5900445 | 4313 | 0.048 | 0.4866 | No | ||
49 | WDR6 | 7050154 | 4470 | 0.045 | 0.4798 | No | ||
50 | GNG8 | 4920358 | 4813 | 0.037 | 0.4626 | No | ||
51 | CEL | 2640278 | 4963 | 0.034 | 0.4558 | No | ||
52 | TACC2 | 580092 1400364 2650497 2690315 5360338 | 5020 | 0.033 | 0.4540 | No | ||
53 | AHR | 4560671 | 5148 | 0.031 | 0.4483 | No | ||
54 | SNAP25 | 360520 | 5174 | 0.031 | 0.4481 | No | ||
55 | LRCH4 | 5220279 6510026 | 5192 | 0.031 | 0.4483 | No | ||
56 | SCUBE2 | 2850315 5130040 | 5355 | 0.028 | 0.4406 | No | ||
57 | H2AFY | 4730750 | 5489 | 0.027 | 0.4344 | No | ||
58 | DNMT3A | 4050068 4810717 | 5636 | 0.025 | 0.4274 | No | ||
59 | NFE2 | 3710373 | 5851 | 0.022 | 0.4166 | No | ||
60 | CDH3 | 5390112 6860603 | 5865 | 0.022 | 0.4167 | No | ||
61 | CD2AP | 1940369 | 5874 | 0.022 | 0.4171 | No | ||
62 | LAMC2 | 450692 2680041 4200059 4670148 | 5902 | 0.022 | 0.4164 | No | ||
63 | IL4 | 6020537 | 6057 | 0.020 | 0.4088 | No | ||
64 | SCN3B | 840112 1780152 5910685 6100131 | 6070 | 0.020 | 0.4089 | No | ||
65 | KCNJ11 | 2510131 | 6145 | 0.019 | 0.4056 | No | ||
66 | POU4F1 | 2260315 | 6280 | 0.018 | 0.3990 | No | ||
67 | DMD | 1740041 3990332 | 6288 | 0.018 | 0.3993 | No | ||
68 | FGF9 | 1050195 | 6503 | 0.016 | 0.3883 | No | ||
69 | SMTN | 670563 1190438 | 6612 | 0.016 | 0.3831 | No | ||
70 | TNNT3 | 1570239 | 6676 | 0.015 | 0.3802 | No | ||
71 | ERBB3 | 5890372 | 6738 | 0.015 | 0.3775 | No | ||
72 | SCNN1G | 520600 | 6802 | 0.014 | 0.3746 | No | ||
73 | DSG2 | 360528 2630603 | 6907 | 0.014 | 0.3695 | No | ||
74 | KLHL1 | 6350021 | 6961 | 0.013 | 0.3671 | No | ||
75 | PPP1R14C | 2570692 5290204 6420184 | 6971 | 0.013 | 0.3671 | No | ||
76 | SLC24A3 | 5080707 | 7337 | 0.011 | 0.3477 | No | ||
77 | IL17C | 5690347 | 7439 | 0.011 | 0.3426 | No | ||
78 | DSTN | 3140592 | 7562 | 0.010 | 0.3364 | No | ||
79 | MESDC1 | 2030019 | 7568 | 0.010 | 0.3365 | No | ||
80 | SSH3 | 6290110 6650497 | 7585 | 0.010 | 0.3360 | No | ||
81 | FOXA1 | 3710609 | 7746 | 0.009 | 0.3277 | No | ||
82 | MAB21L1 | 1450634 1580092 | 7800 | 0.009 | 0.3252 | No | ||
83 | HCRTR1 | 1580273 | 7895 | 0.009 | 0.3204 | No | ||
84 | PDE1C | 3940600 | 8090 | 0.008 | 0.3102 | No | ||
85 | EDG2 | 6290215 | 8239 | 0.008 | 0.3025 | No | ||
86 | JAG1 | 3440390 | 8486 | 0.007 | 0.2894 | No | ||
87 | FBXO24 | 1230132 4610121 | 8765 | 0.006 | 0.2745 | No | ||
88 | DOC2A | 6020121 | 8847 | 0.005 | 0.2703 | No | ||
89 | HOXA11 | 6980133 | 8875 | 0.005 | 0.2691 | No | ||
90 | ACTA1 | 840538 | 9335 | 0.004 | 0.2443 | No | ||
91 | EYA1 | 1450278 5220390 | 9394 | 0.004 | 0.2413 | No | ||
92 | CACNB3 | 2480035 4540184 | 9501 | 0.003 | 0.2357 | No | ||
93 | LRRN1 | 3290154 | 9805 | 0.003 | 0.2194 | No | ||
94 | CHX10 | 3830184 | 9908 | 0.002 | 0.2139 | No | ||
95 | MTUS1 | 780348 4920609 | 9978 | 0.002 | 0.2103 | No | ||
96 | DDAH1 | 6400750 | 10019 | 0.002 | 0.2082 | No | ||
97 | SLC30A3 | 1850451 | 10057 | 0.002 | 0.2062 | No | ||
98 | RPS6KB1 | 1450427 5080110 6200563 | 10168 | 0.002 | 0.2003 | No | ||
99 | NGFR | 3140102 | 10282 | 0.001 | 0.1943 | No | ||
100 | SYT2 | 60609 | 10459 | 0.001 | 0.1847 | No | ||
101 | CHRM1 | 4280619 | 10570 | 0.000 | 0.1788 | No | ||
102 | TECTA | 2570372 | 10577 | 0.000 | 0.1785 | No | ||
103 | EDG1 | 4200619 | 10622 | 0.000 | 0.1761 | No | ||
104 | CRMP1 | 4810014 | 10777 | -0.000 | 0.1678 | No | ||
105 | TLX2 | 1090128 2900451 | 10882 | -0.000 | 0.1622 | No | ||
106 | KHDRBS2 | 3520717 | 11079 | -0.001 | 0.1516 | No | ||
107 | TACSTD1 | 3780025 | 11131 | -0.001 | 0.1488 | No | ||
108 | MMP16 | 2680139 | 11236 | -0.001 | 0.1433 | No | ||
109 | FST | 1110600 | 11431 | -0.002 | 0.1328 | No | ||
110 | SLC9A7 | 5360301 | 11466 | -0.002 | 0.1311 | No | ||
111 | SSX2IP | 4610176 | 11579 | -0.002 | 0.1251 | No | ||
112 | AP1S2 | 780279 4280707 | 11656 | -0.003 | 0.1211 | No | ||
113 | NPEPPS | 2630731 | 12053 | -0.004 | 0.0997 | No | ||
114 | ARTN | 360670 1170333 1500520 | 12150 | -0.004 | 0.0947 | No | ||
115 | GPR126 | 6650204 | 12277 | -0.005 | 0.0881 | No | ||
116 | ZNF462 | 6900100 | 12514 | -0.006 | 0.0755 | No | ||
117 | TCF2 | 870338 5050632 | 12666 | -0.007 | 0.0675 | No | ||
118 | DIO2 | 380504 540403 | 12717 | -0.007 | 0.0651 | No | ||
119 | JUB | 5860711 5900500 | 12939 | -0.008 | 0.0534 | No | ||
120 | DSCAML1 | 1850403 5550079 | 12963 | -0.008 | 0.0525 | No | ||
121 | PFTK1 | 1780181 | 13095 | -0.009 | 0.0457 | No | ||
122 | NGFB | 2630019 | 13131 | -0.009 | 0.0441 | No | ||
123 | SDPR | 3360292 | 13162 | -0.009 | 0.0428 | No | ||
124 | PVRL4 | 2340048 6220195 | 13340 | -0.011 | 0.0336 | No | ||
125 | DSCAM | 1780050 2450731 2810438 | 13347 | -0.011 | 0.0337 | No | ||
126 | FUT8 | 1340068 2340056 | 13420 | -0.011 | 0.0302 | No | ||
127 | PIM2 | 840136 5720692 7100577 | 13667 | -0.013 | 0.0174 | No | ||
128 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 13885 | -0.015 | 0.0062 | No | ||
129 | PLCB2 | 360132 | 14047 | -0.017 | -0.0019 | No | ||
130 | ITGA6 | 3830129 | 14056 | -0.017 | -0.0017 | No | ||
131 | USP15 | 610592 3520504 | 14108 | -0.018 | -0.0038 | No | ||
132 | PDGFA | 6020095 | 14144 | -0.018 | -0.0051 | No | ||
133 | JMJD1C | 940575 2120025 | 14213 | -0.019 | -0.0080 | No | ||
134 | POU4F2 | 2120195 2570022 | 14328 | -0.021 | -0.0134 | No | ||
135 | CCKAR | 4210079 | 14340 | -0.021 | -0.0132 | No | ||
136 | MLLT3 | 510204 3850722 6200088 | 14464 | -0.023 | -0.0190 | No | ||
137 | CRB3 | 6940091 | 14633 | -0.027 | -0.0271 | No | ||
138 | SEMA4G | 5890026 | 14791 | -0.031 | -0.0345 | No | ||
139 | MKL1 | 6840161 | 14993 | -0.037 | -0.0440 | No | ||
140 | ADAM12 | 3390132 4070347 | 15020 | -0.038 | -0.0440 | No | ||
141 | NRF1 | 2650195 | 15109 | -0.042 | -0.0473 | No | ||
142 | SH2D3C | 3060014 | 15296 | -0.049 | -0.0555 | No | ||
143 | FA2H | 730672 | 15317 | -0.050 | -0.0548 | No | ||
144 | PNOC | 1990114 | 15353 | -0.052 | -0.0548 | No | ||
145 | SSBP4 | 2570735 | 15431 | -0.056 | -0.0569 | No | ||
146 | THRA | 6770341 110164 1990600 | 15479 | -0.059 | -0.0572 | No | ||
147 | LIMK2 | 2650446 4050164 | 15579 | -0.065 | -0.0602 | No | ||
148 | L3MBTL2 | 6020341 | 15707 | -0.074 | -0.0643 | No | ||
149 | NTRK3 | 4050687 4070167 4610026 6100484 | 15820 | -0.083 | -0.0673 | No | ||
150 | LSP1 | 2350091 | 15949 | -0.092 | -0.0709 | No | ||
151 | CHRNB1 | 1190671 | 15952 | -0.092 | -0.0676 | No | ||
152 | SLC16A6 | 1690156 | 16092 | -0.104 | -0.0713 | No | ||
153 | MYH10 | 2640673 | 16127 | -0.107 | -0.0692 | No | ||
154 | CAMTA2 | 3990075 | 16303 | -0.125 | -0.0741 | No | ||
155 | LYL1 | 2900242 | 16403 | -0.136 | -0.0744 | No | ||
156 | CXCR4 | 4590519 | 16470 | -0.146 | -0.0726 | No | ||
157 | SLC7A11 | 2850138 | 16767 | -0.190 | -0.0816 | No | ||
158 | PPP1R16B | 3520300 | 16886 | -0.212 | -0.0802 | No | ||
159 | MAPK14 | 5290731 | 17146 | -0.262 | -0.0845 | No | ||
160 | PLAGL2 | 1770148 | 17310 | -0.305 | -0.0821 | No | ||
161 | SFRS7 | 2760408 | 17496 | -0.354 | -0.0790 | No | ||
162 | FLNB | 2510575 | 17638 | -0.405 | -0.0717 | No | ||
163 | NCOR1 | 3710132 | 17768 | -0.450 | -0.0621 | No | ||
164 | BCL7A | 4560095 | 17881 | -0.495 | -0.0499 | No | ||
165 | ROCK1 | 130044 | 17976 | -0.542 | -0.0349 | No | ||
166 | WDR5 | 4150736 | 18188 | -0.664 | -0.0218 | No | ||
167 | CIZ1 | 4150128 6130484 | 18524 | -1.218 | 0.0050 | No |