Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4_01 |
Enrichment Score (ES) | 0.53698134 |
Normalized Enrichment Score (NES) | 1.4011688 |
Nominal p-value | 0.012638231 |
FDR q-value | 0.7354598 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SFRS2 | 50707 380593 | 7 | 4.052 | 0.1020 | Yes | ||
2 | SLC35B1 | 5700064 7000735 | 20 | 2.812 | 0.1724 | Yes | ||
3 | ETV5 | 110017 | 54 | 1.975 | 0.2205 | Yes | ||
4 | NCDN | 50040 1980739 3520603 | 77 | 1.599 | 0.2597 | Yes | ||
5 | ENO1 | 5340128 | 90 | 1.526 | 0.2976 | Yes | ||
6 | NDRG2 | 450403 | 104 | 1.446 | 0.3335 | Yes | ||
7 | PADI4 | 1740075 4810441 | 204 | 1.039 | 0.3544 | Yes | ||
8 | EPHB2 | 1090288 1410377 2100541 | 207 | 1.036 | 0.3804 | Yes | ||
9 | CHST1 | 50601 | 229 | 0.989 | 0.4043 | Yes | ||
10 | UBE2E3 | 2030347 3840471 | 269 | 0.933 | 0.4258 | Yes | ||
11 | ITM2B | 1850482 5860671 6200014 | 329 | 0.839 | 0.4438 | Yes | ||
12 | ECM1 | 940068 5390309 | 352 | 0.800 | 0.4628 | Yes | ||
13 | CD68 | 6350450 | 575 | 0.578 | 0.4653 | Yes | ||
14 | FBXO44 | 4760372 | 585 | 0.570 | 0.4793 | Yes | ||
15 | TYSND1 | 2940273 | 648 | 0.532 | 0.4893 | Yes | ||
16 | ALDOA | 6290672 | 779 | 0.478 | 0.4944 | Yes | ||
17 | SQSTM1 | 6550056 | 1025 | 0.393 | 0.4910 | Yes | ||
18 | ITPKC | 5420021 | 1128 | 0.366 | 0.4947 | Yes | ||
19 | RIT1 | 5390338 | 1212 | 0.352 | 0.4991 | Yes | ||
20 | BAG2 | 2900324 | 1373 | 0.320 | 0.4985 | Yes | ||
21 | PSTPIP1 | 3190156 | 1505 | 0.293 | 0.4988 | Yes | ||
22 | FSTL1 | 2900113 | 1570 | 0.282 | 0.5025 | Yes | ||
23 | BACH1 | 290195 | 1578 | 0.281 | 0.5092 | Yes | ||
24 | PEA15 | 4590685 | 1580 | 0.281 | 0.5162 | Yes | ||
25 | ADCK4 | 1660180 | 1795 | 0.247 | 0.5108 | Yes | ||
26 | HSPB8 | 540563 | 1848 | 0.238 | 0.5140 | Yes | ||
27 | ROM1 | 3130685 | 1921 | 0.228 | 0.5159 | Yes | ||
28 | RPS6KA4 | 2190524 | 2037 | 0.211 | 0.5149 | Yes | ||
29 | ABCD1 | 5670373 | 2091 | 0.203 | 0.5172 | Yes | ||
30 | MNT | 4920575 | 2116 | 0.200 | 0.5210 | Yes | ||
31 | USP3 | 2060332 | 2126 | 0.198 | 0.5255 | Yes | ||
32 | RHBDF1 | 380538 | 2160 | 0.194 | 0.5286 | Yes | ||
33 | CLIC1 | 110600 | 2161 | 0.194 | 0.5335 | Yes | ||
34 | VASP | 7050500 | 2187 | 0.191 | 0.5370 | Yes | ||
35 | CAMKK1 | 6370324 | 2357 | 0.169 | 0.5321 | No | ||
36 | COL16A1 | 1780520 | 2369 | 0.168 | 0.5357 | No | ||
37 | HDAC3 | 4060072 | 2427 | 0.161 | 0.5367 | No | ||
38 | MARK4 | 730519 | 2601 | 0.142 | 0.5309 | No | ||
39 | SYTL1 | 510487 | 2663 | 0.136 | 0.5310 | No | ||
40 | TUBB4 | 5310681 | 2695 | 0.132 | 0.5327 | No | ||
41 | PSME4 | 380348 1770131 | 2759 | 0.127 | 0.5324 | No | ||
42 | VDR | 130156 510438 | 2988 | 0.107 | 0.5228 | No | ||
43 | SEC24D | 3060279 | 3041 | 0.104 | 0.5226 | No | ||
44 | ITGB4 | 1740021 3840482 | 3214 | 0.093 | 0.5156 | No | ||
45 | CDH23 | 4250242 5290397 6550397 | 3237 | 0.091 | 0.5167 | No | ||
46 | GADD45A | 2900717 | 3324 | 0.086 | 0.5142 | No | ||
47 | DUSP14 | 1230358 | 3325 | 0.086 | 0.5164 | No | ||
48 | MMP9 | 580338 | 3401 | 0.082 | 0.5144 | No | ||
49 | SLC26A9 | 3440722 5340088 7510093 | 3412 | 0.081 | 0.5159 | No | ||
50 | USP2 | 1190292 1240253 4850035 | 3858 | 0.062 | 0.4933 | No | ||
51 | COL7A1 | 1230168 2190072 | 3924 | 0.060 | 0.4913 | No | ||
52 | DDIT3 | 780373 | 3950 | 0.059 | 0.4914 | No | ||
53 | SLC38A3 | 5340142 | 3963 | 0.059 | 0.4923 | No | ||
54 | PRX | 2260400 4200347 | 4010 | 0.057 | 0.4912 | No | ||
55 | NRAS | 6900577 | 4135 | 0.053 | 0.4858 | No | ||
56 | NR1D1 | 2360471 770746 6590204 | 4145 | 0.053 | 0.4867 | No | ||
57 | LTBP3 | 1190162 2650440 6520451 | 4242 | 0.050 | 0.4827 | No | ||
58 | GJA1 | 5220731 | 4258 | 0.049 | 0.4832 | No | ||
59 | CSMD3 | 1660427 1940687 | 4325 | 0.047 | 0.4808 | No | ||
60 | SFN | 6290301 7510608 | 4428 | 0.045 | 0.4764 | No | ||
61 | RB1CC1 | 510494 7100072 | 4445 | 0.045 | 0.4767 | No | ||
62 | AP2M1 | 2570338 | 4495 | 0.044 | 0.4751 | No | ||
63 | PKP3 | 3710048 | 4836 | 0.037 | 0.4576 | No | ||
64 | SYNGR1 | 5130452 6650056 | 4853 | 0.036 | 0.4576 | No | ||
65 | PAPPA | 4230463 | 4975 | 0.034 | 0.4519 | No | ||
66 | TREX1 | 3450040 7100692 | 5057 | 0.033 | 0.4484 | No | ||
67 | CSF3 | 2230193 6660707 | 5195 | 0.031 | 0.4417 | No | ||
68 | ADCY8 | 6760519 | 5627 | 0.025 | 0.4190 | No | ||
69 | LAMC2 | 450692 2680041 4200059 4670148 | 5902 | 0.022 | 0.4046 | No | ||
70 | ELAVL2 | 360181 | 5914 | 0.022 | 0.4046 | No | ||
71 | BLMH | 1410438 | 5939 | 0.021 | 0.4038 | No | ||
72 | GKN1 | 5420091 | 5986 | 0.021 | 0.4019 | No | ||
73 | MARK1 | 450484 | 6011 | 0.021 | 0.4011 | No | ||
74 | AK5 | 6290348 | 6061 | 0.020 | 0.3989 | No | ||
75 | MYOZ2 | 1050253 | 6113 | 0.020 | 0.3967 | No | ||
76 | RIMS1 | 5670022 | 6291 | 0.018 | 0.3875 | No | ||
77 | VIT | 6620301 | 6531 | 0.016 | 0.3750 | No | ||
78 | ELK3 | 460377 1400762 3710497 | 6616 | 0.016 | 0.3708 | No | ||
79 | CHST4 | 1190008 | 6825 | 0.014 | 0.3599 | No | ||
80 | PPP1R9B | 3130619 | 6884 | 0.014 | 0.3571 | No | ||
81 | DIRAS1 | 2640270 | 6923 | 0.014 | 0.3553 | No | ||
82 | BTK | 3130044 | 7004 | 0.013 | 0.3513 | No | ||
83 | SPATS2 | 2360066 | 7110 | 0.013 | 0.3460 | No | ||
84 | AQP5 | 3830451 | 7399 | 0.011 | 0.3306 | No | ||
85 | SHC3 | 2690398 | 7559 | 0.010 | 0.3222 | No | ||
86 | GDNF | 4050487 5720739 | 7598 | 0.010 | 0.3204 | No | ||
87 | PRDM1 | 3170347 3520301 | 7781 | 0.009 | 0.3108 | No | ||
88 | SV2B | 3850717 | 7817 | 0.009 | 0.3091 | No | ||
89 | COBL | 2480452 6110066 | 7916 | 0.009 | 0.3040 | No | ||
90 | SLC26A1 | 2190142 | 7918 | 0.009 | 0.3042 | No | ||
91 | MYBPH | 2190711 | 8041 | 0.008 | 0.2978 | No | ||
92 | PVALB | 5570450 | 8167 | 0.008 | 0.2912 | No | ||
93 | CMYA1 | 6900632 | 8212 | 0.008 | 0.2890 | No | ||
94 | NTN4 | 6940398 | 8217 | 0.008 | 0.2890 | No | ||
95 | TLL1 | 2680315 | 8219 | 0.008 | 0.2891 | No | ||
96 | BNIP3 | 3140270 | 8305 | 0.007 | 0.2847 | No | ||
97 | LRRTM3 | 4210021 | 8321 | 0.007 | 0.2841 | No | ||
98 | MAMDC2 | 430471 | 8447 | 0.007 | 0.2775 | No | ||
99 | IBRDC2 | 5130041 | 8456 | 0.007 | 0.2772 | No | ||
100 | WDFY3 | 3610041 4560333 4570273 | 8653 | 0.006 | 0.2667 | No | ||
101 | HOXA11 | 6980133 | 8875 | 0.005 | 0.2548 | No | ||
102 | CRYBA2 | 5900138 | 8949 | 0.005 | 0.2510 | No | ||
103 | SH3RF2 | 6200600 | 8960 | 0.005 | 0.2506 | No | ||
104 | FOSL1 | 430021 | 8996 | 0.005 | 0.2488 | No | ||
105 | MAPRE3 | 7050504 | 9403 | 0.004 | 0.2269 | No | ||
106 | OLR1 | 50025 3840484 | 9512 | 0.003 | 0.2211 | No | ||
107 | ANXA7 | 6110446 | 9653 | 0.003 | 0.2136 | No | ||
108 | MYB | 1660494 5860451 6130706 | 9777 | 0.003 | 0.2070 | No | ||
109 | IGSF9 | 1770411 | 9853 | 0.002 | 0.2030 | No | ||
110 | ESRRG | 4010181 | 9935 | 0.002 | 0.1986 | No | ||
111 | FABP4 | 5050114 | 9941 | 0.002 | 0.1984 | No | ||
112 | LMOD3 | 2120524 | 9975 | 0.002 | 0.1967 | No | ||
113 | PHLDA2 | 4810494 | 10046 | 0.002 | 0.1929 | No | ||
114 | RBP4 | 4540131 | 10088 | 0.002 | 0.1907 | No | ||
115 | PLCD1 | 2030484 | 10136 | 0.002 | 0.1882 | No | ||
116 | SYT2 | 60609 | 10459 | 0.001 | 0.1708 | No | ||
117 | SLC24A4 | 2100487 | 10526 | 0.001 | 0.1672 | No | ||
118 | LOR | 50538 | 10554 | 0.000 | 0.1658 | No | ||
119 | EDG1 | 4200619 | 10622 | 0.000 | 0.1621 | No | ||
120 | AKT3 | 1580270 3290278 | 10642 | 0.000 | 0.1611 | No | ||
121 | WNT7B | 3520039 | 10798 | -0.000 | 0.1527 | No | ||
122 | RGS2 | 1090736 | 10837 | -0.000 | 0.1506 | No | ||
123 | CALB2 | 6130170 6590368 | 10951 | -0.001 | 0.1445 | No | ||
124 | FBXW11 | 6450632 | 11157 | -0.001 | 0.1334 | No | ||
125 | PTPRN | 5900577 | 11167 | -0.001 | 0.1330 | No | ||
126 | FGF11 | 840292 | 11319 | -0.002 | 0.1248 | No | ||
127 | FBXO2 | 6510091 | 11368 | -0.002 | 0.1223 | No | ||
128 | NR0B2 | 2470692 | 11475 | -0.002 | 0.1166 | No | ||
129 | FGF12 | 1740446 2360037 | 11670 | -0.003 | 0.1061 | No | ||
130 | GNAI1 | 4560390 | 12252 | -0.005 | 0.0747 | No | ||
131 | IL11 | 1740398 | 12421 | -0.006 | 0.0657 | No | ||
132 | ABCF3 | 7100100 | 12425 | -0.006 | 0.0657 | No | ||
133 | DHRS3 | 360609 | 12432 | -0.006 | 0.0655 | No | ||
134 | MYH14 | 4010017 | 12550 | -0.006 | 0.0593 | No | ||
135 | GRIA1 | 1340152 3780750 4920440 | 12645 | -0.007 | 0.0544 | No | ||
136 | SNCB | 3360133 | 12674 | -0.007 | 0.0530 | No | ||
137 | UCN2 | 4590372 | 12737 | -0.007 | 0.0498 | No | ||
138 | P2RXL1 | 4730390 5220446 | 12818 | -0.007 | 0.0457 | No | ||
139 | CMAS | 2190129 | 12857 | -0.008 | 0.0438 | No | ||
140 | KCNA2 | 5080403 | 13291 | -0.010 | 0.0206 | No | ||
141 | CRYGS | 2680398 | 13424 | -0.011 | 0.0137 | No | ||
142 | OMG | 6760066 | 13470 | -0.011 | 0.0115 | No | ||
143 | CDKN1A | 4050088 6400706 | 13471 | -0.011 | 0.0118 | No | ||
144 | PSMD11 | 2340538 6510053 | 13573 | -0.012 | 0.0067 | No | ||
145 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | -0.0043 | No | ||
146 | TNXB | 630592 3830020 5360497 7000673 | 14176 | -0.019 | -0.0251 | No | ||
147 | CSF1R | 2340110 6420408 | 14324 | -0.021 | -0.0326 | No | ||
148 | RELA | 3830075 | 14477 | -0.024 | -0.0402 | No | ||
149 | HCN3 | 3940438 6840750 | 14504 | -0.024 | -0.0410 | No | ||
150 | SSH2 | 360056 | 14520 | -0.024 | -0.0412 | No | ||
151 | LAMA3 | 1190131 5290239 | 14790 | -0.031 | -0.0550 | No | ||
152 | TRAF3 | 5690647 | 14967 | -0.036 | -0.0637 | No | ||
153 | DTNA | 1340600 1780731 2340278 2850132 | 14995 | -0.037 | -0.0642 | No | ||
154 | CNTF | 450128 870253 1780068 6520195 | 15090 | -0.041 | -0.0683 | No | ||
155 | BAZ2A | 730184 | 15091 | -0.041 | -0.0672 | No | ||
156 | RIN1 | 510593 | 15099 | -0.041 | -0.0666 | No | ||
157 | ADAM15 | 5890707 | 15157 | -0.044 | -0.0686 | No | ||
158 | BLR1 | 1500300 5420017 | 15171 | -0.044 | -0.0682 | No | ||
159 | LAMC1 | 4730025 | 15203 | -0.045 | -0.0687 | No | ||
160 | FBS1 | 2570520 | 15487 | -0.060 | -0.0826 | No | ||
161 | EN1 | 5360168 7050025 | 15637 | -0.069 | -0.0889 | No | ||
162 | SNX10 | 3800035 | 15677 | -0.072 | -0.0892 | No | ||
163 | DYRK1A | 3190181 | 15694 | -0.073 | -0.0882 | No | ||
164 | BCL9L | 6940053 | 15926 | -0.090 | -0.0985 | No | ||
165 | SLC16A6 | 1690156 | 16092 | -0.104 | -0.1048 | No | ||
166 | WNT6 | 4570364 | 16119 | -0.106 | -0.1036 | No | ||
167 | GTPBP2 | 2760750 | 16140 | -0.108 | -0.1019 | No | ||
168 | XLKD1 | 520441 | 16255 | -0.120 | -0.1051 | No | ||
169 | MAP4K5 | 3190286 4760300 5270070 5550494 | 16724 | -0.183 | -0.1259 | No | ||
170 | ABHD4 | 6760450 | 16760 | -0.188 | -0.1230 | No | ||
171 | PSMD4 | 430068 | 16899 | -0.215 | -0.1251 | No | ||
172 | MPV17 | 1190133 4070427 4570577 | 16939 | -0.221 | -0.1216 | No | ||
173 | XPOT | 7050184 | 16946 | -0.222 | -0.1163 | No | ||
174 | GTF2B | 6860685 | 17024 | -0.236 | -0.1145 | No | ||
175 | HCLS1 | 7100309 | 17030 | -0.237 | -0.1088 | No | ||
176 | NEFH | 630239 | 17051 | -0.242 | -0.1038 | No | ||
177 | IL10 | 2340685 2640541 2850403 6590286 | 17148 | -0.263 | -0.1023 | No | ||
178 | TMEM24 | 5860039 | 17270 | -0.295 | -0.1014 | No | ||
179 | TOB1 | 4150138 | 17435 | -0.340 | -0.1017 | No | ||
180 | RBBP7 | 430113 450450 2370309 | 17510 | -0.357 | -0.0967 | No | ||
181 | RAB3D | 4210253 | 17519 | -0.359 | -0.0881 | No | ||
182 | TAF15 | 4120736 | 17757 | -0.447 | -0.0897 | No | ||
183 | TTC1 | 5890736 | 17789 | -0.459 | -0.0798 | No | ||
184 | VAPA | 2480594 | 17835 | -0.478 | -0.0701 | No | ||
185 | ATP1B1 | 3130594 | 17850 | -0.483 | -0.0587 | No | ||
186 | EMP1 | 4120438 | 18184 | -0.662 | -0.0600 | No | ||
187 | PPP2CA | 3990113 | 18255 | -0.725 | -0.0455 | No | ||
188 | H3F3B | 1410300 | 18257 | -0.727 | -0.0272 | No | ||
189 | SRPK2 | 6380341 | 18312 | -0.780 | -0.0104 | No | ||
190 | RNF34 | 3800332 4590717 5670138 | 18479 | -1.062 | 0.0074 | No |