Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | 0.50276357 |
Normalized Enrichment Score (NES) | 1.2997308 |
Nominal p-value | 0.036507938 |
FDR q-value | 0.8808569 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL27A | 3130451 110195 6840494 | 0 | 8.101 | 0.2165 | Yes | ||
2 | TCF7 | 3800736 5390181 | 14 | 3.219 | 0.3019 | Yes | ||
3 | ETV5 | 110017 | 54 | 1.975 | 0.3526 | Yes | ||
4 | UBQLN1 | 110280 730376 2470133 6590594 | 84 | 1.554 | 0.3925 | Yes | ||
5 | ARRDC4 | 2810019 | 174 | 1.093 | 0.4169 | Yes | ||
6 | ELA1 | 3390167 | 289 | 0.914 | 0.4351 | Yes | ||
7 | LMNA | 520471 1500075 3190167 4210020 | 450 | 0.670 | 0.4444 | Yes | ||
8 | MAPK3 | 580161 4780035 | 477 | 0.653 | 0.4604 | Yes | ||
9 | LIMK1 | 5080064 | 576 | 0.577 | 0.4705 | Yes | ||
10 | TAGLN2 | 4560121 | 639 | 0.534 | 0.4814 | Yes | ||
11 | GNGT2 | 540176 | 862 | 0.447 | 0.4813 | Yes | ||
12 | TBC1D17 | 1780450 | 890 | 0.437 | 0.4915 | Yes | ||
13 | FKBP8 | 4060019 | 973 | 0.412 | 0.4981 | Yes | ||
14 | BAG2 | 2900324 | 1373 | 0.320 | 0.4850 | Yes | ||
15 | CD151 | 1450592 3780309 | 1572 | 0.282 | 0.4818 | Yes | ||
16 | BACH1 | 290195 | 1578 | 0.281 | 0.4890 | Yes | ||
17 | AKT1S1 | 1660048 | 1587 | 0.279 | 0.4961 | Yes | ||
18 | AP2A2 | 130082 | 1725 | 0.257 | 0.4955 | Yes | ||
19 | ROM1 | 3130685 | 1921 | 0.228 | 0.4910 | Yes | ||
20 | USP3 | 2060332 | 2126 | 0.198 | 0.4852 | Yes | ||
21 | TNFRSF12A | 4810253 | 2168 | 0.193 | 0.4882 | Yes | ||
22 | ISG20 | 1770750 | 2214 | 0.188 | 0.4908 | Yes | ||
23 | CAPNS1 | 3940113 | 2215 | 0.188 | 0.4958 | Yes | ||
24 | VIM | 20431 | 2295 | 0.177 | 0.4962 | Yes | ||
25 | SCRN1 | 6040025 6580019 | 2302 | 0.177 | 0.5006 | Yes | ||
26 | CAMKK1 | 6370324 | 2357 | 0.169 | 0.5022 | Yes | ||
27 | HDAC3 | 4060072 | 2427 | 0.161 | 0.5028 | Yes | ||
28 | IGFBP6 | 1580181 | 2623 | 0.140 | 0.4959 | No | ||
29 | SYTL1 | 510487 | 2663 | 0.136 | 0.4974 | No | ||
30 | MMP19 | 5080377 | 2848 | 0.118 | 0.4906 | No | ||
31 | AXIN2 | 3850131 | 2950 | 0.110 | 0.4881 | No | ||
32 | VDR | 130156 510438 | 2988 | 0.107 | 0.4889 | No | ||
33 | LAPTM5 | 5550372 | 3031 | 0.105 | 0.4894 | No | ||
34 | FHL3 | 1090369 2650017 | 3050 | 0.103 | 0.4912 | No | ||
35 | IRAK1 | 4120593 | 3363 | 0.084 | 0.4765 | No | ||
36 | MMP9 | 580338 | 3401 | 0.082 | 0.4767 | No | ||
37 | CLSTN3 | 2350685 | 3453 | 0.079 | 0.4761 | No | ||
38 | STOML2 | 1940487 | 3481 | 0.078 | 0.4767 | No | ||
39 | EIF4E | 1580403 70133 6380215 | 3677 | 0.069 | 0.4679 | No | ||
40 | USP2 | 1190292 1240253 4850035 | 3858 | 0.062 | 0.4598 | No | ||
41 | ABHD2 | 4850504 6840010 | 3865 | 0.062 | 0.4612 | No | ||
42 | MDFI | 6200041 | 3888 | 0.061 | 0.4616 | No | ||
43 | ADORA2A | 1990687 | 3929 | 0.059 | 0.4610 | No | ||
44 | DCTN2 | 540471 3780717 | 4018 | 0.057 | 0.4578 | No | ||
45 | MAP1A | 4920576 | 4047 | 0.056 | 0.4577 | No | ||
46 | HSPB7 | 1190441 | 4132 | 0.053 | 0.4546 | No | ||
47 | NRAS | 6900577 | 4135 | 0.053 | 0.4559 | No | ||
48 | LTBP3 | 1190162 2650440 6520451 | 4242 | 0.050 | 0.4515 | No | ||
49 | CYFIP1 | 5690082 | 4379 | 0.046 | 0.4454 | No | ||
50 | SFN | 6290301 7510608 | 4428 | 0.045 | 0.4440 | No | ||
51 | RB1CC1 | 510494 7100072 | 4445 | 0.045 | 0.4443 | No | ||
52 | GGN | 1410528 4210082 5290170 | 4562 | 0.042 | 0.4391 | No | ||
53 | ABCB6 | 6350138 | 4792 | 0.038 | 0.4277 | No | ||
54 | DUSP13 | 6400152 | 4891 | 0.036 | 0.4234 | No | ||
55 | PAPPA | 4230463 | 4975 | 0.034 | 0.4198 | No | ||
56 | UBE2C | 6130017 | 5158 | 0.031 | 0.4107 | No | ||
57 | GPR3 | 2970452 | 5430 | 0.027 | 0.3968 | No | ||
58 | EPHA2 | 5890056 | 5484 | 0.027 | 0.3946 | No | ||
59 | STAT5B | 6200026 | 5565 | 0.026 | 0.3909 | No | ||
60 | APOB48R | 2810070 | 5584 | 0.025 | 0.3906 | No | ||
61 | LAMC2 | 450692 2680041 4200059 4670148 | 5902 | 0.022 | 0.3740 | No | ||
62 | EEF1A2 | 2260162 5290086 | 5913 | 0.022 | 0.3741 | No | ||
63 | BLMH | 1410438 | 5939 | 0.021 | 0.3733 | No | ||
64 | AK5 | 6290348 | 6061 | 0.020 | 0.3672 | No | ||
65 | NEK6 | 3360687 | 6249 | 0.019 | 0.3576 | No | ||
66 | ESRRB | 3870082 | 6321 | 0.018 | 0.3542 | No | ||
67 | TRIB1 | 2320435 | 6327 | 0.018 | 0.3544 | No | ||
68 | PTPRR | 130121 3990273 | 6416 | 0.017 | 0.3501 | No | ||
69 | HS3ST3B1 | 380040 | 6504 | 0.016 | 0.3458 | No | ||
70 | NRIP3 | 1340372 | 6581 | 0.016 | 0.3421 | No | ||
71 | ELK3 | 460377 1400762 3710497 | 6616 | 0.016 | 0.3407 | No | ||
72 | PPP1R9B | 3130619 | 6884 | 0.014 | 0.3266 | No | ||
73 | PADI3 | 6520072 | 6956 | 0.013 | 0.3231 | No | ||
74 | BTK | 3130044 | 7004 | 0.013 | 0.3209 | No | ||
75 | DNM1 | 1660097 5340519 | 7255 | 0.012 | 0.3077 | No | ||
76 | KBTBD5 | 6350025 | 7470 | 0.011 | 0.2963 | No | ||
77 | SHC3 | 2690398 | 7559 | 0.010 | 0.2918 | No | ||
78 | DSTN | 3140592 | 7562 | 0.010 | 0.2920 | No | ||
79 | GPR150 | 2570440 | 7634 | 0.010 | 0.2884 | No | ||
80 | GJB3 | 2650040 | 7706 | 0.010 | 0.2848 | No | ||
81 | PRDM1 | 3170347 3520301 | 7781 | 0.009 | 0.2811 | No | ||
82 | MYBPH | 2190711 | 8041 | 0.008 | 0.2672 | No | ||
83 | LPP | 1660541 | 8169 | 0.008 | 0.2605 | No | ||
84 | PSMA3 | 5900047 7040161 | 8190 | 0.008 | 0.2597 | No | ||
85 | CMYA1 | 6900632 | 8212 | 0.008 | 0.2587 | No | ||
86 | BNIP3 | 3140270 | 8305 | 0.007 | 0.2539 | No | ||
87 | BMP2 | 6620687 | 8306 | 0.007 | 0.2541 | No | ||
88 | ST18 | 5720537 | 8391 | 0.007 | 0.2498 | No | ||
89 | PCDH9 | 2100136 | 8403 | 0.007 | 0.2493 | No | ||
90 | IBRDC2 | 5130041 | 8456 | 0.007 | 0.2467 | No | ||
91 | GSN | 3830168 | 8632 | 0.006 | 0.2374 | No | ||
92 | WDFY3 | 3610041 4560333 4570273 | 8653 | 0.006 | 0.2364 | No | ||
93 | HOXA11 | 6980133 | 8875 | 0.005 | 0.2246 | No | ||
94 | EIF3S1 | 6130368 6770044 | 8891 | 0.005 | 0.2239 | No | ||
95 | CRYBA2 | 5900138 | 8949 | 0.005 | 0.2210 | No | ||
96 | SH3RF2 | 6200600 | 8960 | 0.005 | 0.2206 | No | ||
97 | IL9 | 3440338 | 9272 | 0.004 | 0.2038 | No | ||
98 | TRPV3 | 540341 | 9327 | 0.004 | 0.2010 | No | ||
99 | EYA1 | 1450278 5220390 | 9394 | 0.004 | 0.1975 | No | ||
100 | MAPRE3 | 7050504 | 9403 | 0.004 | 0.1972 | No | ||
101 | EVI2B | 1050465 | 9629 | 0.003 | 0.1850 | No | ||
102 | ANXA7 | 6110446 | 9653 | 0.003 | 0.1839 | No | ||
103 | PTPRH | 3870070 | 9670 | 0.003 | 0.1831 | No | ||
104 | PLAC1 | 2350594 | 9732 | 0.003 | 0.1798 | No | ||
105 | AP2B1 | 1450184 2370148 3520139 4850593 | 9874 | 0.002 | 0.1723 | No | ||
106 | HOXD3 | 6450154 | 9991 | 0.002 | 0.1660 | No | ||
107 | ZIC1 | 670113 | 10040 | 0.002 | 0.1635 | No | ||
108 | GAB2 | 1410280 2340520 4280040 | 10091 | 0.002 | 0.1608 | No | ||
109 | MMP7 | 1780497 | 10127 | 0.002 | 0.1589 | No | ||
110 | PAX9 | 3850519 | 10506 | 0.001 | 0.1385 | No | ||
111 | EFNA1 | 3840672 | 10588 | 0.000 | 0.1341 | No | ||
112 | IL1RN | 2370333 | 10640 | 0.000 | 0.1313 | No | ||
113 | AKT3 | 1580270 3290278 | 10642 | 0.000 | 0.1313 | No | ||
114 | USP13 | 1450670 | 11099 | -0.001 | 0.1065 | No | ||
115 | FBXW11 | 6450632 | 11157 | -0.001 | 0.1035 | No | ||
116 | PTPRN | 5900577 | 11167 | -0.001 | 0.1030 | No | ||
117 | CCL22 | 6380086 | 11267 | -0.002 | 0.0977 | No | ||
118 | FGF11 | 840292 | 11319 | -0.002 | 0.0950 | No | ||
119 | IL23A | 6290044 | 11512 | -0.002 | 0.0846 | No | ||
120 | AKAP1 | 110148 1740735 2260019 7000563 | 11590 | -0.003 | 0.0805 | No | ||
121 | S100A5 | 4120592 | 11644 | -0.003 | 0.0777 | No | ||
122 | FGF12 | 1740446 2360037 | 11670 | -0.003 | 0.0764 | No | ||
123 | EDN1 | 1770047 | 12016 | -0.004 | 0.0578 | No | ||
124 | FAP | 4560019 | 12032 | -0.004 | 0.0571 | No | ||
125 | GNAI1 | 4560390 | 12252 | -0.005 | 0.0454 | No | ||
126 | LIFR | 3360068 3830102 | 12436 | -0.006 | 0.0356 | No | ||
127 | UCN2 | 4590372 | 12737 | -0.007 | 0.0195 | No | ||
128 | GOLGA4 | 460300 | 12766 | -0.007 | 0.0182 | No | ||
129 | CREM | 840156 6380438 6660041 6660168 | 12788 | -0.007 | 0.0172 | No | ||
130 | CMAS | 2190129 | 12857 | -0.008 | 0.0137 | No | ||
131 | LRP1B | 1450193 | 13290 | -0.010 | -0.0094 | No | ||
132 | IL6 | 380133 | 13300 | -0.010 | -0.0097 | No | ||
133 | CDKN1A | 4050088 6400706 | 13471 | -0.011 | -0.0186 | No | ||
134 | PSMD11 | 2340538 6510053 | 13573 | -0.012 | -0.0237 | No | ||
135 | PIM2 | 840136 5720692 7100577 | 13667 | -0.013 | -0.0284 | No | ||
136 | RAD23B | 2190671 | 13773 | -0.014 | -0.0337 | No | ||
137 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | -0.0338 | No | ||
138 | LRRC15 | 3940609 | 14092 | -0.018 | -0.0501 | No | ||
139 | PITPNC1 | 3990017 | 14207 | -0.019 | -0.0558 | No | ||
140 | UCHL3 | 1240735 | 14335 | -0.021 | -0.0621 | No | ||
141 | APBA2BP | 5700341 | 14798 | -0.031 | -0.0863 | No | ||
142 | ROCK2 | 1780035 5720025 | 14902 | -0.034 | -0.0910 | No | ||
143 | BAZ2A | 730184 | 15091 | -0.041 | -0.1001 | No | ||
144 | RIN1 | 510593 | 15099 | -0.041 | -0.0994 | No | ||
145 | ZIC4 | 1500082 | 15173 | -0.044 | -0.1022 | No | ||
146 | LAMC1 | 4730025 | 15203 | -0.045 | -0.1025 | No | ||
147 | CASK | 2340215 3290576 6770215 | 15358 | -0.052 | -0.1095 | No | ||
148 | RABEP1 | 4760427 6200463 | 15393 | -0.054 | -0.1099 | No | ||
149 | STX17 | 2260037 | 15467 | -0.059 | -0.1123 | No | ||
150 | CORO1C | 4570397 | 15504 | -0.061 | -0.1126 | No | ||
151 | PDGFRB | 6450279 | 15511 | -0.061 | -0.1113 | No | ||
152 | MCART1 | 5270059 | 15567 | -0.065 | -0.1126 | No | ||
153 | POLR3E | 380152 | 15620 | -0.068 | -0.1136 | No | ||
154 | PDE4D | 2470528 6660014 | 15736 | -0.076 | -0.1178 | No | ||
155 | UBE3A | 1240152 2690438 5860609 | 15786 | -0.080 | -0.1183 | No | ||
156 | KCNN4 | 2680129 | 15821 | -0.083 | -0.1180 | No | ||
157 | LRRFIP2 | 670575 730152 6590438 | 15880 | -0.086 | -0.1188 | No | ||
158 | MAP2K1 | 840739 | 16069 | -0.102 | -0.1263 | No | ||
159 | COL27A1 | 1740390 | 16078 | -0.103 | -0.1240 | No | ||
160 | SLC16A6 | 1690156 | 16092 | -0.104 | -0.1219 | No | ||
161 | XLKD1 | 520441 | 16255 | -0.120 | -0.1275 | No | ||
162 | SCOC | 610048 2230053 | 16369 | -0.133 | -0.1301 | No | ||
163 | NFRKB | 3130538 | 16390 | -0.135 | -0.1275 | No | ||
164 | ABI3 | 1740563 | 16509 | -0.151 | -0.1299 | No | ||
165 | APOBEC1 | 4610022 | 16546 | -0.157 | -0.1277 | No | ||
166 | ABHD4 | 6760450 | 16760 | -0.188 | -0.1342 | No | ||
167 | TGFBR2 | 1780711 1980537 6550398 | 16790 | -0.195 | -0.1306 | No | ||
168 | DTX2 | 4210041 7000008 | 16891 | -0.213 | -0.1303 | No | ||
169 | PSMD4 | 430068 | 16899 | -0.215 | -0.1249 | No | ||
170 | XPOT | 7050184 | 16946 | -0.222 | -0.1215 | No | ||
171 | NEFH | 630239 | 17051 | -0.242 | -0.1207 | No | ||
172 | IL10 | 2340685 2640541 2850403 6590286 | 17148 | -0.263 | -0.1188 | No | ||
173 | KCNH2 | 1170451 | 17179 | -0.268 | -0.1133 | No | ||
174 | PDAP1 | 1410735 | 17227 | -0.282 | -0.1083 | No | ||
175 | LAMB3 | 7100301 | 17228 | -0.282 | -0.1008 | No | ||
176 | ICK | 1580746 3140021 | 17268 | -0.294 | -0.0951 | No | ||
177 | RPA3 | 5700136 | 17503 | -0.356 | -0.0982 | No | ||
178 | RBBP7 | 430113 450450 2370309 | 17510 | -0.357 | -0.0890 | No | ||
179 | EIF4G1 | 4070446 | 17816 | -0.472 | -0.0930 | No | ||
180 | TRIM8 | 6130441 | 17883 | -0.496 | -0.0833 | No | ||
181 | PKN3 | 2260538 | 17914 | -0.513 | -0.0712 | No | ||
182 | EEF1A1 | 1980193 1990195 4670735 | 17923 | -0.517 | -0.0578 | No | ||
183 | RTN4 | 50725 630647 870097 870184 | 18214 | -0.685 | -0.0553 | No | ||
184 | SRPK2 | 6380341 | 18312 | -0.780 | -0.0397 | No | ||
185 | TCF12 | 3610324 7000156 | 18397 | -0.880 | -0.0207 | No | ||
186 | CIZ1 | 4150128 6130484 | 18524 | -1.218 | 0.0050 | No |