Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_01 |
Enrichment Score (ES) | 0.5006772 |
Normalized Enrichment Score (NES) | 1.3028761 |
Nominal p-value | 0.025559105 |
FDR q-value | 0.9117588 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TCF7 | 3800736 5390181 | 14 | 3.219 | 0.0944 | Yes | ||
2 | SLC11A1 | 940286 2810435 6370647 | 15 | 3.189 | 0.1887 | Yes | ||
3 | NCDN | 50040 1980739 3520603 | 77 | 1.599 | 0.2326 | Yes | ||
4 | ENO1 | 5340128 | 90 | 1.526 | 0.2771 | Yes | ||
5 | ARHGAP8 | 380333 5390487 | 148 | 1.174 | 0.3087 | Yes | ||
6 | SLC38A2 | 1470242 3800026 | 180 | 1.086 | 0.3391 | Yes | ||
7 | PADI4 | 1740075 4810441 | 204 | 1.039 | 0.3686 | Yes | ||
8 | LMNA | 520471 1500075 3190167 4210020 | 450 | 0.670 | 0.3751 | Yes | ||
9 | POLD4 | 2320082 | 466 | 0.660 | 0.3938 | Yes | ||
10 | TAGLN2 | 4560121 | 639 | 0.534 | 0.4002 | Yes | ||
11 | ALDOA | 6290672 | 779 | 0.478 | 0.4068 | Yes | ||
12 | ALS2CR2 | 6450128 7100092 | 809 | 0.464 | 0.4190 | Yes | ||
13 | GNGT2 | 540176 | 862 | 0.447 | 0.4293 | Yes | ||
14 | SQSTM1 | 6550056 | 1025 | 0.393 | 0.4322 | Yes | ||
15 | GPSM3 | 2690154 | 1181 | 0.356 | 0.4343 | Yes | ||
16 | PSMD2 | 4670706 5050364 | 1184 | 0.356 | 0.4447 | Yes | ||
17 | RIT1 | 5390338 | 1212 | 0.352 | 0.4536 | Yes | ||
18 | GABARAPL1 | 2810458 | 1295 | 0.336 | 0.4591 | Yes | ||
19 | BAG2 | 2900324 | 1373 | 0.320 | 0.4644 | Yes | ||
20 | BACH1 | 290195 | 1578 | 0.281 | 0.4616 | Yes | ||
21 | TBXAS1 | 5050053 6900286 | 1579 | 0.281 | 0.4699 | Yes | ||
22 | PEA15 | 4590685 | 1580 | 0.281 | 0.4782 | Yes | ||
23 | ADCK4 | 1660180 | 1795 | 0.247 | 0.4739 | Yes | ||
24 | HSPB8 | 540563 | 1848 | 0.238 | 0.4781 | Yes | ||
25 | ROM1 | 3130685 | 1921 | 0.228 | 0.4809 | Yes | ||
26 | EMP3 | 1500722 1570039 | 2042 | 0.210 | 0.4806 | Yes | ||
27 | ABCD1 | 5670373 | 2091 | 0.203 | 0.4840 | Yes | ||
28 | CLIC1 | 110600 | 2161 | 0.194 | 0.4860 | Yes | ||
29 | TNFRSF12A | 4810253 | 2168 | 0.193 | 0.4914 | Yes | ||
30 | VASP | 7050500 | 2187 | 0.191 | 0.4961 | Yes | ||
31 | ABCA2 | 5050039 | 2296 | 0.177 | 0.4954 | Yes | ||
32 | VAT1 | 1050040 | 2297 | 0.177 | 0.5007 | Yes | ||
33 | HDAC3 | 4060072 | 2427 | 0.161 | 0.4984 | No | ||
34 | PIM1 | 630047 | 2596 | 0.143 | 0.4935 | No | ||
35 | TUBB4 | 5310681 | 2695 | 0.132 | 0.4921 | No | ||
36 | VDR | 130156 510438 | 2988 | 0.107 | 0.4795 | No | ||
37 | WASF2 | 4850592 | 3142 | 0.098 | 0.4741 | No | ||
38 | CDH23 | 4250242 5290397 6550397 | 3237 | 0.091 | 0.4717 | No | ||
39 | ADRA1A | 1230446 2260390 | 3302 | 0.088 | 0.4708 | No | ||
40 | GADD45A | 2900717 | 3324 | 0.086 | 0.4722 | No | ||
41 | DUSP14 | 1230358 | 3325 | 0.086 | 0.4747 | No | ||
42 | IRAK1 | 4120593 | 3363 | 0.084 | 0.4752 | No | ||
43 | CCL27 | 2120070 | 3633 | 0.071 | 0.4627 | No | ||
44 | SERTAD1 | 2680332 | 3635 | 0.071 | 0.4647 | No | ||
45 | MMRN2 | 1740047 | 3670 | 0.069 | 0.4649 | No | ||
46 | MDFI | 6200041 | 3888 | 0.061 | 0.4550 | No | ||
47 | COL7A1 | 1230168 2190072 | 3924 | 0.060 | 0.4548 | No | ||
48 | SLC38A3 | 5340142 | 3963 | 0.059 | 0.4545 | No | ||
49 | DCTN2 | 540471 3780717 | 4018 | 0.057 | 0.4533 | No | ||
50 | MAPK12 | 450022 1340717 7050484 | 4113 | 0.054 | 0.4497 | No | ||
51 | CSMD3 | 1660427 1940687 | 4325 | 0.047 | 0.4397 | No | ||
52 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4349 | 0.047 | 0.4398 | No | ||
53 | RB1CC1 | 510494 7100072 | 4445 | 0.045 | 0.4360 | No | ||
54 | MRGPRF | 4780746 | 4462 | 0.045 | 0.4365 | No | ||
55 | ABCB6 | 6350138 | 4792 | 0.038 | 0.4197 | No | ||
56 | SYNGR1 | 5130452 6650056 | 4853 | 0.036 | 0.4175 | No | ||
57 | DUSP13 | 6400152 | 4891 | 0.036 | 0.4166 | No | ||
58 | CSF3 | 2230193 6660707 | 5195 | 0.031 | 0.4011 | No | ||
59 | EPHA2 | 5890056 | 5484 | 0.027 | 0.3862 | No | ||
60 | HSD3B7 | 1410129 | 5598 | 0.025 | 0.3808 | No | ||
61 | PPP2R5B | 2900441 | 5807 | 0.023 | 0.3702 | No | ||
62 | UBXD3 | 5050193 | 5818 | 0.023 | 0.3703 | No | ||
63 | ITGAX | 6130524 | 5894 | 0.022 | 0.3669 | No | ||
64 | IVL | 4560500 | 5899 | 0.022 | 0.3673 | No | ||
65 | EEF1A2 | 2260162 5290086 | 5913 | 0.022 | 0.3673 | No | ||
66 | ELAVL2 | 360181 | 5914 | 0.022 | 0.3679 | No | ||
67 | MARK1 | 450484 | 6011 | 0.021 | 0.3633 | No | ||
68 | MYOZ2 | 1050253 | 6113 | 0.020 | 0.3584 | No | ||
69 | NEK6 | 3360687 | 6249 | 0.019 | 0.3516 | No | ||
70 | DMD | 1740041 3990332 | 6288 | 0.018 | 0.3501 | No | ||
71 | TRIB1 | 2320435 | 6327 | 0.018 | 0.3486 | No | ||
72 | PTPRR | 130121 3990273 | 6416 | 0.017 | 0.3443 | No | ||
73 | FGF9 | 1050195 | 6503 | 0.016 | 0.3401 | No | ||
74 | NRIP3 | 1340372 | 6581 | 0.016 | 0.3364 | No | ||
75 | SLC35E4 | 2370711 | 6813 | 0.014 | 0.3243 | No | ||
76 | CHST4 | 1190008 | 6825 | 0.014 | 0.3241 | No | ||
77 | PPP1R9B | 3130619 | 6884 | 0.014 | 0.3214 | No | ||
78 | DIRAS1 | 2640270 | 6923 | 0.014 | 0.3197 | No | ||
79 | BTK | 3130044 | 7004 | 0.013 | 0.3158 | No | ||
80 | SPATS2 | 2360066 | 7110 | 0.013 | 0.3105 | No | ||
81 | NUDT11 | 3840239 | 7378 | 0.011 | 0.2963 | No | ||
82 | AQP5 | 3830451 | 7399 | 0.011 | 0.2956 | No | ||
83 | SMPX | 6590440 | 7422 | 0.011 | 0.2947 | No | ||
84 | SHC3 | 2690398 | 7559 | 0.010 | 0.2876 | No | ||
85 | GDNF | 4050487 5720739 | 7598 | 0.010 | 0.2858 | No | ||
86 | IDS | 360619 5720161 | 7714 | 0.010 | 0.2799 | No | ||
87 | SV2B | 3850717 | 7817 | 0.009 | 0.2746 | No | ||
88 | SLC26A1 | 2190142 | 7918 | 0.009 | 0.2695 | No | ||
89 | ANGPT1 | 3990368 5130288 6770035 | 7959 | 0.009 | 0.2675 | No | ||
90 | PVALB | 5570450 | 8167 | 0.008 | 0.2565 | No | ||
91 | PSMA3 | 5900047 7040161 | 8190 | 0.008 | 0.2556 | No | ||
92 | CMYA1 | 6900632 | 8212 | 0.008 | 0.2547 | No | ||
93 | TLL1 | 2680315 | 8219 | 0.008 | 0.2546 | No | ||
94 | COL5A3 | 1940471 | 8300 | 0.007 | 0.2504 | No | ||
95 | BNIP3 | 3140270 | 8305 | 0.007 | 0.2504 | No | ||
96 | SCEL | 3190129 | 8364 | 0.007 | 0.2475 | No | ||
97 | ST18 | 5720537 | 8391 | 0.007 | 0.2463 | No | ||
98 | EIF3S1 | 6130368 6770044 | 8891 | 0.005 | 0.2194 | No | ||
99 | SH3RF2 | 6200600 | 8960 | 0.005 | 0.2158 | No | ||
100 | FOSL1 | 430021 | 8996 | 0.005 | 0.2141 | No | ||
101 | CPNE8 | 7040039 | 9158 | 0.004 | 0.2055 | No | ||
102 | TRPV3 | 540341 | 9327 | 0.004 | 0.1965 | No | ||
103 | EYA1 | 1450278 5220390 | 9394 | 0.004 | 0.1930 | No | ||
104 | MAPRE3 | 7050504 | 9403 | 0.004 | 0.1927 | No | ||
105 | OLR1 | 50025 3840484 | 9512 | 0.003 | 0.1869 | No | ||
106 | ANXA7 | 6110446 | 9653 | 0.003 | 0.1794 | No | ||
107 | SFTPC | 3290133 | 9725 | 0.003 | 0.1756 | No | ||
108 | MYB | 1660494 5860451 6130706 | 9777 | 0.003 | 0.1729 | No | ||
109 | IGSF9 | 1770411 | 9853 | 0.002 | 0.1689 | No | ||
110 | PHLDA2 | 4810494 | 10046 | 0.002 | 0.1586 | No | ||
111 | RBP4 | 4540131 | 10088 | 0.002 | 0.1564 | No | ||
112 | MMP7 | 1780497 | 10127 | 0.002 | 0.1544 | No | ||
113 | PLCD1 | 2030484 | 10136 | 0.002 | 0.1540 | No | ||
114 | SYT2 | 60609 | 10459 | 0.001 | 0.1366 | No | ||
115 | AKT3 | 1580270 3290278 | 10642 | 0.000 | 0.1267 | No | ||
116 | SPRED1 | 6940706 | 10651 | 0.000 | 0.1263 | No | ||
117 | SERPINB5 | 6940050 | 10942 | -0.001 | 0.1105 | No | ||
118 | CALB2 | 6130170 6590368 | 10951 | -0.001 | 0.1101 | No | ||
119 | USP13 | 1450670 | 11099 | -0.001 | 0.1022 | No | ||
120 | ASB5 | 2760575 | 11107 | -0.001 | 0.1018 | No | ||
121 | PTPRN | 5900577 | 11167 | -0.001 | 0.0987 | No | ||
122 | ATP6V0D2 | 7050541 | 11529 | -0.002 | 0.0791 | No | ||
123 | FGF12 | 1740446 2360037 | 11670 | -0.003 | 0.0716 | No | ||
124 | HS6ST2 | 520133 5550603 | 12293 | -0.005 | 0.0380 | No | ||
125 | IL11 | 1740398 | 12421 | -0.006 | 0.0313 | No | ||
126 | ABCF3 | 7100100 | 12425 | -0.006 | 0.0313 | No | ||
127 | DHRS3 | 360609 | 12432 | -0.006 | 0.0311 | No | ||
128 | GFAP | 2060092 | 12518 | -0.006 | 0.0267 | No | ||
129 | SNCB | 3360133 | 12674 | -0.007 | 0.0185 | No | ||
130 | LENEP | 4850369 | 12762 | -0.007 | 0.0140 | No | ||
131 | ATP6V1C2 | 6620092 | 12782 | -0.007 | 0.0131 | No | ||
132 | P2RXL1 | 4730390 5220446 | 12818 | -0.007 | 0.0115 | No | ||
133 | TAC1 | 7000195 380706 | 12833 | -0.007 | 0.0109 | No | ||
134 | CMAS | 2190129 | 12857 | -0.008 | 0.0099 | No | ||
135 | PFTK1 | 1780181 | 13095 | -0.009 | -0.0027 | No | ||
136 | LRP1B | 1450193 | 13290 | -0.010 | -0.0129 | No | ||
137 | KCNA2 | 5080403 | 13291 | -0.010 | -0.0126 | No | ||
138 | IL6 | 380133 | 13300 | -0.010 | -0.0128 | No | ||
139 | OMG | 6760066 | 13470 | -0.011 | -0.0216 | No | ||
140 | CDKN1A | 4050088 6400706 | 13471 | -0.011 | -0.0212 | No | ||
141 | PSMD11 | 2340538 6510053 | 13573 | -0.012 | -0.0264 | No | ||
142 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | -0.0372 | No | ||
143 | TNXB | 630592 3830020 5360497 7000673 | 14176 | -0.019 | -0.0580 | No | ||
144 | RPS20 | 1740092 | 14489 | -0.024 | -0.0742 | No | ||
145 | HCN3 | 3940438 6840750 | 14504 | -0.024 | -0.0743 | No | ||
146 | SSH2 | 360056 | 14520 | -0.024 | -0.0744 | No | ||
147 | SLC22A18 | 7050168 | 14706 | -0.029 | -0.0836 | No | ||
148 | MAPK10 | 6110193 | 14756 | -0.030 | -0.0853 | No | ||
149 | LAMA3 | 1190131 5290239 | 14790 | -0.031 | -0.0862 | No | ||
150 | APBA2BP | 5700341 | 14798 | -0.031 | -0.0857 | No | ||
151 | GSTP1 | 3170102 3710707 5080368 | 14832 | -0.032 | -0.0865 | No | ||
152 | TRAF3 | 5690647 | 14967 | -0.036 | -0.0927 | No | ||
153 | DTNA | 1340600 1780731 2340278 2850132 | 14995 | -0.037 | -0.0931 | No | ||
154 | NLK | 2030010 2450041 | 15071 | -0.040 | -0.0960 | No | ||
155 | BAZ2A | 730184 | 15091 | -0.041 | -0.0958 | No | ||
156 | RIN1 | 510593 | 15099 | -0.041 | -0.0950 | No | ||
157 | LAMC1 | 4730025 | 15203 | -0.045 | -0.0992 | No | ||
158 | LY6D | 4050010 | 15235 | -0.047 | -0.0995 | No | ||
159 | GADD45G | 2510142 | 15301 | -0.049 | -0.1016 | No | ||
160 | ULK1 | 6100315 | 15303 | -0.049 | -0.1002 | No | ||
161 | SNCG | 3120725 | 15445 | -0.057 | -0.1062 | No | ||
162 | STX17 | 2260037 | 15467 | -0.059 | -0.1056 | No | ||
163 | FBS1 | 2570520 | 15487 | -0.060 | -0.1048 | No | ||
164 | HEPH | 2940176 3390040 6100195 6900575 7100170 | 15526 | -0.062 | -0.1051 | No | ||
165 | MCART1 | 5270059 | 15567 | -0.065 | -0.1053 | No | ||
166 | SNX10 | 3800035 | 15677 | -0.072 | -0.1091 | No | ||
167 | LRRFIP2 | 670575 730152 6590438 | 15880 | -0.086 | -0.1175 | No | ||
168 | VCL | 4120487 | 15892 | -0.087 | -0.1155 | No | ||
169 | COL27A1 | 1740390 | 16078 | -0.103 | -0.1225 | No | ||
170 | ABI3 | 1740563 | 16509 | -0.151 | -0.1414 | No | ||
171 | APOBEC1 | 4610022 | 16546 | -0.157 | -0.1387 | No | ||
172 | ABHD4 | 6760450 | 16760 | -0.188 | -0.1447 | No | ||
173 | TGFBR2 | 1780711 1980537 6550398 | 16790 | -0.195 | -0.1405 | No | ||
174 | DTX2 | 4210041 7000008 | 16891 | -0.213 | -0.1397 | No | ||
175 | GTF2B | 6860685 | 17024 | -0.236 | -0.1399 | No | ||
176 | MECP2 | 1940450 | 17253 | -0.290 | -0.1437 | No | ||
177 | ICK | 1580746 3140021 | 17268 | -0.294 | -0.1357 | No | ||
178 | RBBP7 | 430113 450450 2370309 | 17510 | -0.357 | -0.1383 | No | ||
179 | RAB3D | 4210253 | 17519 | -0.359 | -0.1281 | No | ||
180 | PSMD12 | 730044 | 17531 | -0.365 | -0.1179 | No | ||
181 | YWHAG | 3780341 | 17650 | -0.409 | -0.1122 | No | ||
182 | VAPA | 2480594 | 17835 | -0.478 | -0.1081 | No | ||
183 | ATP1B1 | 3130594 | 17850 | -0.483 | -0.0945 | No | ||
184 | EEF1A1 | 1980193 1990195 4670735 | 17923 | -0.517 | -0.0832 | No | ||
185 | NEDD4L | 6380368 | 17955 | -0.535 | -0.0690 | No | ||
186 | DLX1 | 360168 | 17968 | -0.540 | -0.0537 | No | ||
187 | PSMD7 | 2030619 6220594 | 18080 | -0.604 | -0.0419 | No | ||
188 | LUC7L | 6040156 6110411 | 18088 | -0.608 | -0.0243 | No | ||
189 | PPP2CA | 3990113 | 18255 | -0.725 | -0.0119 | No | ||
190 | RNF34 | 3800332 4590717 5670138 | 18479 | -1.062 | 0.0074 | No |