Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | SYATTGTG_UNKNOWN |
Enrichment Score (ES) | -0.6742651 |
Normalized Enrichment Score (NES) | -1.7916147 |
Nominal p-value | 0.0 |
FDR q-value | 0.0049610385 |
FWER p-Value | 0.019 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SIRT6 | 540731 1400735 | 353 | 0.798 | 0.0089 | No | ||
2 | CLU | 5420075 | 579 | 0.576 | 0.0169 | No | ||
3 | IFRD2 | 4150110 | 641 | 0.533 | 0.0324 | No | ||
4 | EXT1 | 4540603 | 985 | 0.408 | 0.0281 | No | ||
5 | BCL2L11 | 780044 4200601 | 1056 | 0.384 | 0.0378 | No | ||
6 | NDST2 | 6290711 | 1847 | 0.238 | 0.0034 | No | ||
7 | OTUB1 | 610551 | 2318 | 0.174 | -0.0159 | No | ||
8 | PDYN | 5720408 | 2370 | 0.167 | -0.0128 | No | ||
9 | TOMM40 | 6110017 | 2584 | 0.145 | -0.0192 | No | ||
10 | LIG1 | 1980438 4540112 5570609 | 2620 | 0.140 | -0.0162 | No | ||
11 | TLE3 | 580040 4730121 | 2706 | 0.131 | -0.0162 | No | ||
12 | RABAC1 | 2030435 2100632 | 2906 | 0.114 | -0.0230 | No | ||
13 | CBX8 | 50671 | 2942 | 0.111 | -0.0210 | No | ||
14 | ITPR3 | 4010632 | 3022 | 0.105 | -0.0216 | No | ||
15 | CFL2 | 380239 6200368 | 3215 | 0.093 | -0.0287 | No | ||
16 | PYGO1 | 840575 | 3292 | 0.089 | -0.0297 | No | ||
17 | ETV4 | 2450605 | 3367 | 0.084 | -0.0308 | No | ||
18 | NFIL3 | 4070377 | 3429 | 0.081 | -0.0312 | No | ||
19 | EGR3 | 6940128 | 3572 | 0.073 | -0.0364 | No | ||
20 | POFUT1 | 1570458 | 3909 | 0.060 | -0.0524 | No | ||
21 | RNF38 | 1940746 3140133 3840601 | 4305 | 0.048 | -0.0721 | No | ||
22 | GRIA3 | 2900164 6130278 6860154 | 4480 | 0.044 | -0.0800 | No | ||
23 | OLFML3 | 7100463 | 4638 | 0.040 | -0.0871 | No | ||
24 | PCSK1N | 4010435 | 4695 | 0.039 | -0.0887 | No | ||
25 | ATE1 | 290491 6940722 | 4767 | 0.038 | -0.0912 | No | ||
26 | PPP2R5C | 3310121 6650672 | 4881 | 0.036 | -0.0961 | No | ||
27 | NNT | 540253 1170471 5550092 6760397 | 4904 | 0.036 | -0.0960 | No | ||
28 | PRDM13 | 1430022 | 5121 | 0.032 | -0.1066 | No | ||
29 | SCUBE2 | 2850315 5130040 | 5355 | 0.028 | -0.1182 | No | ||
30 | FOXP2 | 3520561 4150372 4760524 | 5510 | 0.026 | -0.1256 | No | ||
31 | IBSP | 2060048 | 5800 | 0.023 | -0.1405 | No | ||
32 | DLL1 | 1770377 | 5809 | 0.023 | -0.1401 | No | ||
33 | CELSR3 | 5270731 7100082 | 6034 | 0.021 | -0.1515 | No | ||
34 | REC8L1 | 5900014 | 6089 | 0.020 | -0.1537 | No | ||
35 | TRIB1 | 2320435 | 6327 | 0.018 | -0.1659 | No | ||
36 | SMAD1 | 630537 1850333 | 6399 | 0.017 | -0.1691 | No | ||
37 | CA3 | 870687 5890390 | 6492 | 0.016 | -0.1735 | No | ||
38 | SH3BGRL2 | 1780239 | 6743 | 0.015 | -0.1866 | No | ||
39 | NFIB | 460450 | 6954 | 0.013 | -0.1974 | No | ||
40 | BCL11A | 6860369 | 6996 | 0.013 | -0.1992 | No | ||
41 | CLDN17 | 3710672 | 7106 | 0.013 | -0.2047 | No | ||
42 | BAT4 | 2690128 6220451 | 7180 | 0.012 | -0.2082 | No | ||
43 | ACRV1 | 4070161 | 7280 | 0.012 | -0.2131 | No | ||
44 | FMR1 | 5050075 | 7468 | 0.011 | -0.2229 | No | ||
45 | RAB3C | 5420072 | 7542 | 0.010 | -0.2265 | No | ||
46 | MYH2 | 2340433 | 7547 | 0.010 | -0.2263 | No | ||
47 | MB | 730019 | 7641 | 0.010 | -0.2310 | No | ||
48 | RNGTT | 780152 780746 1090471 | 8183 | 0.008 | -0.2600 | No | ||
49 | TSNAXIP1 | 1770270 6180577 | 8203 | 0.008 | -0.2608 | No | ||
50 | MEIS1 | 1400575 | 8236 | 0.008 | -0.2622 | No | ||
51 | CBLB | 3520465 4670348 | 8240 | 0.008 | -0.2621 | No | ||
52 | GPM6A | 1660044 2750152 | 8430 | 0.007 | -0.2721 | No | ||
53 | PLXNC1 | 5860315 | 8449 | 0.007 | -0.2729 | No | ||
54 | HOXC4 | 1940193 | 8556 | 0.006 | -0.2784 | No | ||
55 | RFX4 | 3710100 5340215 | 9169 | 0.004 | -0.3113 | No | ||
56 | ADAM22 | 5390368 | 9370 | 0.004 | -0.3220 | No | ||
57 | CSNK2B | 5080161 | 9414 | 0.004 | -0.3242 | No | ||
58 | SLITRK4 | 5910022 | 9456 | 0.004 | -0.3263 | No | ||
59 | DPYSL3 | 1580594 | 9761 | 0.003 | -0.3427 | No | ||
60 | GSH1 | 2760242 | 9969 | 0.002 | -0.3538 | No | ||
61 | FSCN3 | 60093 | 10038 | 0.002 | -0.3574 | No | ||
62 | BAG5 | 2230368 6420537 | 10407 | 0.001 | -0.3773 | No | ||
63 | PCDH8 | 2360047 4200452 | 10518 | 0.001 | -0.3832 | No | ||
64 | LAMA1 | 1770594 | 10719 | 0.000 | -0.3941 | No | ||
65 | PITX2 | 870537 2690139 | 11222 | -0.001 | -0.4212 | No | ||
66 | MMP16 | 2680139 | 11236 | -0.001 | -0.4218 | No | ||
67 | PAX3 | 50551 | 11246 | -0.001 | -0.4223 | No | ||
68 | CA2 | 1660113 1660600 | 11477 | -0.002 | -0.4346 | No | ||
69 | SF4 | 3830341 | 11519 | -0.002 | -0.4368 | No | ||
70 | ASB17 | 3520433 | 11528 | -0.002 | -0.4371 | No | ||
71 | MYL3 | 6040563 | 11536 | -0.002 | -0.4374 | No | ||
72 | OPHN1 | 2360100 | 11876 | -0.003 | -0.4557 | No | ||
73 | PRIMA1 | 1500673 6760671 | 12035 | -0.004 | -0.4641 | No | ||
74 | RTN1 | 4150452 4850176 | 12377 | -0.005 | -0.4823 | No | ||
75 | GRIK3 | 6380592 | 12607 | -0.006 | -0.4945 | No | ||
76 | UCN2 | 4590372 | 12737 | -0.007 | -0.5013 | No | ||
77 | REST | 1500471 | 12748 | -0.007 | -0.5015 | No | ||
78 | LIN28 | 6590672 | 12789 | -0.007 | -0.5035 | No | ||
79 | HOXA2 | 2120121 | 13074 | -0.009 | -0.5185 | No | ||
80 | TNP1 | 3120048 | 13190 | -0.009 | -0.5244 | No | ||
81 | FGF14 | 2630390 3520075 6770048 | 13438 | -0.011 | -0.5374 | No | ||
82 | OMG | 6760066 | 13470 | -0.011 | -0.5387 | No | ||
83 | GRIN2B | 3800333 | 13618 | -0.013 | -0.5462 | No | ||
84 | GALC | 2260685 4810161 6370040 | 13697 | -0.013 | -0.5499 | No | ||
85 | NNAT | 4920053 5130253 | 13725 | -0.014 | -0.5509 | No | ||
86 | BSN | 5270347 | 13834 | -0.015 | -0.5563 | No | ||
87 | SLC36A3 | 430075 | 14086 | -0.018 | -0.5692 | No | ||
88 | FGF17 | 3130022 | 14126 | -0.018 | -0.5707 | No | ||
89 | HOXC6 | 3850133 4920736 | 14137 | -0.018 | -0.5706 | No | ||
90 | PVRL3 | 1400324 4200593 6650128 | 14161 | -0.019 | -0.5712 | No | ||
91 | CCNT2 | 2100390 4150563 | 14196 | -0.019 | -0.5724 | No | ||
92 | ARHGEF19 | 940102 | 14235 | -0.020 | -0.5737 | No | ||
93 | FEZ1 | 2630725 4810324 | 14256 | -0.020 | -0.5741 | No | ||
94 | NR4A3 | 2900021 5860095 5910039 | 14482 | -0.024 | -0.5855 | No | ||
95 | RPL30 | 4810369 | 14519 | -0.024 | -0.5865 | No | ||
96 | HOXA7 | 5910152 | 14596 | -0.026 | -0.5897 | No | ||
97 | CHD4 | 5420059 6130338 6380717 | 14631 | -0.027 | -0.5906 | No | ||
98 | KIF21A | 2970338 | 14704 | -0.028 | -0.5935 | No | ||
99 | MAPK10 | 6110193 | 14756 | -0.030 | -0.5952 | No | ||
100 | SEMA3A | 1780064 | 14789 | -0.031 | -0.5959 | No | ||
101 | CLDN5 | 6510717 | 15007 | -0.038 | -0.6063 | No | ||
102 | ERG | 50154 1770739 | 15200 | -0.045 | -0.6151 | No | ||
103 | CASK | 2340215 3290576 6770215 | 15358 | -0.052 | -0.6218 | No | ||
104 | GJA12 | 430273 4560731 | 15411 | -0.055 | -0.6227 | No | ||
105 | CAMK2A | 1740333 1940112 4150292 | 15420 | -0.055 | -0.6212 | No | ||
106 | POLR3E | 380152 | 15620 | -0.068 | -0.6296 | No | ||
107 | YTHDF3 | 4540632 4670717 7040609 | 15687 | -0.073 | -0.6306 | No | ||
108 | GUCA1A | 6020338 | 15768 | -0.079 | -0.6321 | No | ||
109 | NSD1 | 4560519 4780672 | 16074 | -0.102 | -0.6451 | No | ||
110 | FOXP1 | 6510433 | 16107 | -0.105 | -0.6431 | No | ||
111 | ORMDL3 | 1340711 | 16141 | -0.108 | -0.6411 | No | ||
112 | ELOVL5 | 3800170 | 16156 | -0.110 | -0.6380 | No | ||
113 | THAP11 | 6940025 | 16191 | -0.113 | -0.6359 | No | ||
114 | YWHAZ | 1230717 | 16461 | -0.145 | -0.6453 | No | ||
115 | MYO1C | 3190398 | 16642 | -0.172 | -0.6490 | No | ||
116 | ARIH1 | 6900025 | 17109 | -0.254 | -0.6653 | Yes | ||
117 | YTHDF2 | 4060332 4610279 | 17187 | -0.271 | -0.6600 | Yes | ||
118 | PDAP1 | 1410735 | 17227 | -0.282 | -0.6522 | Yes | ||
119 | PLAGL2 | 1770148 | 17310 | -0.305 | -0.6460 | Yes | ||
120 | BCL2L1 | 1580452 4200152 5420484 | 17359 | -0.321 | -0.6373 | Yes | ||
121 | KCNF1 | 2650687 | 17593 | -0.385 | -0.6364 | Yes | ||
122 | WASF1 | 2060484 | 17675 | -0.419 | -0.6261 | Yes | ||
123 | DDX3X | 2190020 | 17682 | -0.421 | -0.6116 | Yes | ||
124 | RANBP10 | 2340184 | 17696 | -0.424 | -0.5974 | Yes | ||
125 | AHCYL1 | 540609 | 17737 | -0.440 | -0.5841 | Yes | ||
126 | EIF4G1 | 4070446 | 17816 | -0.472 | -0.5718 | Yes | ||
127 | MAPK6 | 6760520 | 17829 | -0.477 | -0.5557 | Yes | ||
128 | BCL7A | 4560095 | 17881 | -0.495 | -0.5411 | Yes | ||
129 | SOX4 | 2260091 | 17896 | -0.506 | -0.5241 | Yes | ||
130 | DLX1 | 360168 | 17968 | -0.540 | -0.5090 | Yes | ||
131 | TRIM39 | 6550441 | 17988 | -0.549 | -0.4907 | Yes | ||
132 | KLF13 | 4670563 | 17991 | -0.551 | -0.4715 | Yes | ||
133 | CGGBP1 | 4810053 | 18005 | -0.559 | -0.4526 | Yes | ||
134 | CUTL1 | 1570113 1770091 1850273 2100286 5340605 | 18448 | -0.967 | -0.4425 | Yes | ||
135 | SFRS6 | 60224 | 18454 | -0.997 | -0.4078 | Yes | ||
136 | PIK3R3 | 1770333 | 18458 | -1.005 | -0.3727 | Yes | ||
137 | HSPB2 | 1990110 | 18460 | -1.011 | -0.3372 | Yes | ||
138 | ABI1 | 2850152 | 18542 | -1.353 | -0.2941 | Yes | ||
139 | HNRPH1 | 1170086 3140546 3290471 6110184 6110373 | 18591 | -1.818 | -0.2329 | Yes | ||
140 | ILF3 | 940722 3190647 6520110 | 18599 | -2.087 | -0.1600 | Yes | ||
141 | TPM3 | 670600 3170296 5670167 6650471 | 18614 | -4.583 | 0.0001 | Yes |