Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | -0.6458002 |
Normalized Enrichment Score (NES) | -1.8091807 |
Nominal p-value | 0.0 |
FDR q-value | 0.0038628348 |
FWER p-Value | 0.0080 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HRBL | 1850102 3830253 4780176 | 177 | 1.090 | 0.0170 | No | ||
2 | ACOT7 | 730735 1400176 7050053 | 212 | 1.019 | 0.0400 | No | ||
3 | PSEN1 | 130403 2030647 6100603 | 332 | 0.837 | 0.0540 | No | ||
4 | DMWD | 770019 1690047 | 838 | 0.456 | 0.0376 | No | ||
5 | CDC42BPB | 6350037 | 1560 | 0.284 | 0.0054 | No | ||
6 | BHLHB2 | 7040603 | 1637 | 0.269 | 0.0078 | No | ||
7 | ST3GAL3 | 2810601 | 1711 | 0.259 | 0.0102 | No | ||
8 | STAT5A | 2680458 | 1906 | 0.230 | 0.0052 | No | ||
9 | SERF2 | 5720010 | 1962 | 0.220 | 0.0076 | No | ||
10 | EPN1 | 4060725 | 2107 | 0.201 | 0.0047 | No | ||
11 | HIC2 | 4010433 | 2259 | 0.182 | 0.0009 | No | ||
12 | TOP1 | 770471 4060632 6650324 | 2420 | 0.162 | -0.0038 | No | ||
13 | SON | 3120148 5860239 7040403 | 2451 | 0.158 | -0.0016 | No | ||
14 | ACACA | 2490612 2680369 | 2604 | 0.142 | -0.0064 | No | ||
15 | AMPD2 | 630093 1170070 | 2731 | 0.129 | -0.0101 | No | ||
16 | FRMD4A | 2190176 | 2775 | 0.126 | -0.0094 | No | ||
17 | DEK | 1050451 4560037 | 2824 | 0.121 | -0.0090 | No | ||
18 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 3176 | 0.096 | -0.0258 | No | ||
19 | TAF12 | 3710746 4920300 6180603 | 3221 | 0.092 | -0.0259 | No | ||
20 | DLC1 | 1090632 6450594 | 3281 | 0.089 | -0.0270 | No | ||
21 | SYT4 | 5080193 | 3521 | 0.076 | -0.0381 | No | ||
22 | SPRYD3 | 50403 | 3668 | 0.069 | -0.0443 | No | ||
23 | PEX5 | 1240746 1570092 2510487 | 3690 | 0.069 | -0.0438 | No | ||
24 | ATXN1 | 5550156 | 3707 | 0.068 | -0.0430 | No | ||
25 | KIF1C | 2480484 | 4088 | 0.055 | -0.0623 | No | ||
26 | PPT2 | 2340059 3450148 | 4092 | 0.055 | -0.0612 | No | ||
27 | MDGA1 | 1170139 | 4419 | 0.046 | -0.0778 | No | ||
28 | SOX5 | 2370576 2900167 3190128 5050528 | 4427 | 0.045 | -0.0771 | No | ||
29 | PAPPA | 4230463 | 4975 | 0.034 | -0.1060 | No | ||
30 | CYP26B1 | 2630142 | 5071 | 0.033 | -0.1103 | No | ||
31 | GPC2 | 130647 | 5104 | 0.032 | -0.1113 | No | ||
32 | CSF3 | 2230193 6660707 | 5195 | 0.031 | -0.1154 | No | ||
33 | SIM2 | 2100044 | 5204 | 0.031 | -0.1151 | No | ||
34 | RAB38 | 2970735 | 5262 | 0.030 | -0.1175 | No | ||
35 | CNP | 2260451 | 5290 | 0.029 | -0.1182 | No | ||
36 | EPHA2 | 5890056 | 5484 | 0.027 | -0.1281 | No | ||
37 | STAT5B | 6200026 | 5565 | 0.026 | -0.1318 | No | ||
38 | STRN | 5570706 7050333 | 5649 | 0.025 | -0.1357 | No | ||
39 | KLHL18 | 4560075 | 5768 | 0.023 | -0.1416 | No | ||
40 | LRRC8A | 2510193 | 5793 | 0.023 | -0.1423 | No | ||
41 | CPD | 5360403 5860685 | 5864 | 0.022 | -0.1456 | No | ||
42 | ELAVL2 | 360181 | 5914 | 0.022 | -0.1477 | No | ||
43 | USP9X | 130435 2370735 3120338 | 5965 | 0.021 | -0.1499 | No | ||
44 | PPP2R2A | 2900014 5700575 | 6127 | 0.020 | -0.1582 | No | ||
45 | JUN | 840170 | 6162 | 0.019 | -0.1596 | No | ||
46 | POU4F1 | 2260315 | 6280 | 0.018 | -0.1655 | No | ||
47 | ELF2 | 1690014 2480132 3060180 3190504 | 6401 | 0.017 | -0.1716 | No | ||
48 | HOXB5 | 2900538 | 6404 | 0.017 | -0.1713 | No | ||
49 | BRUNOL6 | 6840373 | 6532 | 0.016 | -0.1778 | No | ||
50 | PTPRG | 2650524 1340022 | 6668 | 0.015 | -0.1848 | No | ||
51 | CNR1 | 6550494 6760497 | 6673 | 0.015 | -0.1846 | No | ||
52 | TGFB2 | 4920292 | 6784 | 0.015 | -0.1902 | No | ||
53 | TM9SF4 | 450538 1050093 4210112 | 6883 | 0.014 | -0.1952 | No | ||
54 | SLC17A6 | 4210576 | 6919 | 0.014 | -0.1968 | No | ||
55 | TTYH2 | 1450397 3870100 6550347 | 7523 | 0.011 | -0.2293 | No | ||
56 | DRD2 | 5890369 | 7533 | 0.010 | -0.2295 | No | ||
57 | SEMA6A | 2690138 3060021 | 7550 | 0.010 | -0.2302 | No | ||
58 | LYPLA1 | 4480373 5570551 | 7708 | 0.010 | -0.2385 | No | ||
59 | WDR26 | 1090138 | 7720 | 0.010 | -0.2388 | No | ||
60 | FOXA1 | 3710609 | 7746 | 0.009 | -0.2400 | No | ||
61 | TMEFF1 | 2680100 | 7775 | 0.009 | -0.2412 | No | ||
62 | CALCR | 1690494 | 7822 | 0.009 | -0.2435 | No | ||
63 | APBB2 | 5130403 | 7950 | 0.009 | -0.2502 | No | ||
64 | HLF | 2370113 | 8006 | 0.008 | -0.2530 | No | ||
65 | SNF1LK | 6110403 | 8069 | 0.008 | -0.2562 | No | ||
66 | B3GNT1 | 2350446 | 8163 | 0.008 | -0.2610 | No | ||
67 | LPP | 1660541 | 8169 | 0.008 | -0.2611 | No | ||
68 | PCDH9 | 2100136 | 8403 | 0.007 | -0.2736 | No | ||
69 | RBM7 | 5890348 | 8639 | 0.006 | -0.2863 | No | ||
70 | WDFY3 | 3610041 4560333 4570273 | 8653 | 0.006 | -0.2868 | No | ||
71 | LHX6 | 2360731 3360397 | 8660 | 0.006 | -0.2870 | No | ||
72 | HOXA11 | 6980133 | 8875 | 0.005 | -0.2985 | No | ||
73 | EPHA7 | 1190288 4010278 | 8914 | 0.005 | -0.3004 | No | ||
74 | CSNK1A1 | 2340427 | 8950 | 0.005 | -0.3022 | No | ||
75 | ZFR | 5910647 | 9102 | 0.005 | -0.3103 | No | ||
76 | GPM6B | 6220458 | 9134 | 0.005 | -0.3119 | No | ||
77 | ACVR2A | 6110647 | 9155 | 0.004 | -0.3129 | No | ||
78 | GRIN3A | 2370592 | 9203 | 0.004 | -0.3153 | No | ||
79 | STK35 | 2360121 | 9313 | 0.004 | -0.3211 | No | ||
80 | CHES1 | 4570121 5700162 | 9351 | 0.004 | -0.3231 | No | ||
81 | ZCCHC3 | 580438 1990035 4780278 | 9415 | 0.004 | -0.3264 | No | ||
82 | ITSN1 | 2640577 | 9530 | 0.003 | -0.3325 | No | ||
83 | ESRRG | 4010181 | 9935 | 0.002 | -0.3544 | No | ||
84 | LENG8 | 3130731 | 10014 | 0.002 | -0.3586 | No | ||
85 | DIXDC1 | 6980435 | 10052 | 0.002 | -0.3606 | No | ||
86 | SP4 | 3850176 | 10068 | 0.002 | -0.3613 | No | ||
87 | PAFAH1B2 | 5360546 6860672 | 10221 | 0.001 | -0.3696 | No | ||
88 | SPG3A | 2760091 3120170 | 10281 | 0.001 | -0.3728 | No | ||
89 | NR2C2 | 6100097 | 10395 | 0.001 | -0.3789 | No | ||
90 | PCDH8 | 2360047 4200452 | 10518 | 0.001 | -0.3855 | No | ||
91 | HNRPF | 670138 | 10938 | -0.001 | -0.4083 | No | ||
92 | SLC1A1 | 520372 6420059 | 10965 | -0.001 | -0.4097 | No | ||
93 | SLC16A7 | 2320672 | 11006 | -0.001 | -0.4118 | No | ||
94 | MYT1L | 5670369 6660403 | 11048 | -0.001 | -0.4140 | No | ||
95 | KHDRBS2 | 3520717 | 11079 | -0.001 | -0.4156 | No | ||
96 | PITX2 | 870537 2690139 | 11222 | -0.001 | -0.4233 | No | ||
97 | MMP16 | 2680139 | 11236 | -0.001 | -0.4240 | No | ||
98 | DUSP3 | 1240129 6840215 | 11395 | -0.002 | -0.4325 | No | ||
99 | CLASP2 | 2510139 | 11410 | -0.002 | -0.4332 | No | ||
100 | TRHDE | 1690068 | 11482 | -0.002 | -0.4371 | No | ||
101 | DR1 | 5860750 | 11702 | -0.003 | -0.4489 | No | ||
102 | PLAG1 | 1450142 3870139 6520039 | 11708 | -0.003 | -0.4491 | No | ||
103 | ATXN7 | 1450435 | 11748 | -0.003 | -0.4511 | No | ||
104 | CXCL12 | 580546 4150750 4570068 | 11890 | -0.003 | -0.4587 | No | ||
105 | PHYHIPL | 2360706 3840692 | 12069 | -0.004 | -0.4683 | No | ||
106 | SNAP91 | 3170056 5690520 | 12200 | -0.005 | -0.4753 | No | ||
107 | NRP2 | 4070400 5860041 6650446 | 12300 | -0.005 | -0.4805 | No | ||
108 | SRC | 580132 | 12358 | -0.005 | -0.4835 | No | ||
109 | THRB | 1780673 | 12363 | -0.005 | -0.4836 | No | ||
110 | MYRIP | 1580471 | 12467 | -0.006 | -0.4890 | No | ||
111 | MTSS1 | 780435 2370114 | 12551 | -0.006 | -0.4934 | No | ||
112 | RARB | 430139 1410138 | 12595 | -0.006 | -0.4956 | No | ||
113 | SOX11 | 610279 | 12649 | -0.007 | -0.4983 | No | ||
114 | HOXC13 | 4070722 | 12721 | -0.007 | -0.5020 | No | ||
115 | TSC1 | 1850672 | 13010 | -0.008 | -0.5175 | No | ||
116 | PTP4A1 | 130692 | 13146 | -0.009 | -0.5246 | No | ||
117 | EXOC5 | 7000711 | 13177 | -0.009 | -0.5260 | No | ||
118 | ARPC5 | 1740411 3450300 | 13252 | -0.010 | -0.5297 | No | ||
119 | TCERG1 | 2350551 4540397 5220746 | 13257 | -0.010 | -0.5297 | No | ||
120 | FGFR2 | 4670601 5570402 6940377 | 13508 | -0.012 | -0.5430 | No | ||
121 | HIPK1 | 110193 | 13664 | -0.013 | -0.5511 | No | ||
122 | RAD23B | 2190671 | 13773 | -0.014 | -0.5567 | No | ||
123 | TIAL1 | 4150048 6510605 | 13782 | -0.014 | -0.5568 | No | ||
124 | E2F3 | 50162 460180 | 13841 | -0.015 | -0.5596 | No | ||
125 | KCNJ2 | 630019 | 13954 | -0.016 | -0.5653 | No | ||
126 | RPH3AL | 70110 | 13990 | -0.016 | -0.5668 | No | ||
127 | PCTK2 | 5700673 | 13993 | -0.016 | -0.5665 | No | ||
128 | RTN4RL1 | 2630368 | 14008 | -0.017 | -0.5668 | No | ||
129 | NRXN1 | 460408 5340270 6370066 | 14072 | -0.017 | -0.5698 | No | ||
130 | STXBP1 | 360072 6220717 | 14090 | -0.018 | -0.5703 | No | ||
131 | PHLPP | 3440563 | 14217 | -0.019 | -0.5767 | No | ||
132 | CSNK2A1 | 1580577 | 14243 | -0.020 | -0.5776 | No | ||
133 | NFASC | 1940619 2470156 4590168 6840524 | 14244 | -0.020 | -0.5771 | No | ||
134 | OLFM1 | 3360161 5570066 | 14254 | -0.020 | -0.5771 | No | ||
135 | HMG20A | 4590113 | 14303 | -0.021 | -0.5792 | No | ||
136 | THRAP2 | 4920600 | 14429 | -0.023 | -0.5854 | No | ||
137 | KPNA3 | 7040088 | 14468 | -0.023 | -0.5869 | No | ||
138 | DDX5 | 940021 2630338 3440148 | 14471 | -0.023 | -0.5864 | No | ||
139 | QKI | 5220093 6130044 | 14486 | -0.024 | -0.5866 | No | ||
140 | SEPT7 | 2760685 | 14644 | -0.027 | -0.5945 | No | ||
141 | PBEF1 | 1090278 | 14713 | -0.029 | -0.5975 | No | ||
142 | OLIG3 | 1050603 | 14736 | -0.030 | -0.5980 | No | ||
143 | SLC39A9 | 3940348 | 14860 | -0.033 | -0.6039 | No | ||
144 | TTR | 4150072 | 14951 | -0.035 | -0.6079 | No | ||
145 | CBL | 6380068 | 14966 | -0.036 | -0.6078 | No | ||
146 | TNS3 | 6380242 | 14994 | -0.037 | -0.6083 | No | ||
147 | GATA6 | 1770010 | 15086 | -0.041 | -0.6123 | No | ||
148 | CALU | 2680403 3520056 4610348 5720176 6130121 | 15145 | -0.043 | -0.6144 | No | ||
149 | FBXL2 | 6450722 | 15242 | -0.047 | -0.6185 | No | ||
150 | CHD9 | 430037 2570129 5420398 | 15256 | -0.048 | -0.6180 | No | ||
151 | BICD2 | 1090411 | 15367 | -0.053 | -0.6227 | No | ||
152 | BAP1 | 3830131 | 15391 | -0.054 | -0.6227 | No | ||
153 | SPAG9 | 580497 2510180 4210685 | 15416 | -0.055 | -0.6226 | No | ||
154 | PTGES3 | 2190440 2680524 | 15425 | -0.056 | -0.6217 | No | ||
155 | MARCH7 | 3800020 6620168 | 15488 | -0.060 | -0.6236 | No | ||
156 | ATF5 | 5670685 | 15581 | -0.066 | -0.6270 | No | ||
157 | YTHDF3 | 4540632 4670717 7040609 | 15687 | -0.073 | -0.6309 | No | ||
158 | MOBKL2B | 940128 | 15760 | -0.078 | -0.6330 | No | ||
159 | SLC25A3 | 670112 | 15766 | -0.079 | -0.6313 | No | ||
160 | FUS | 4760619 | 15783 | -0.079 | -0.6302 | No | ||
161 | UBE3A | 1240152 2690438 5860609 | 15786 | -0.080 | -0.6284 | No | ||
162 | FOXP1 | 6510433 | 16107 | -0.105 | -0.6432 | Yes | ||
163 | MYH10 | 2640673 | 16127 | -0.107 | -0.6417 | Yes | ||
164 | CDC25A | 3800184 | 16131 | -0.107 | -0.6392 | Yes | ||
165 | WDR44 | 130195 1050609 1570685 | 16137 | -0.108 | -0.6369 | Yes | ||
166 | AK3L1 | 7100601 | 16260 | -0.120 | -0.6406 | Yes | ||
167 | BACE1 | 2650438 | 16270 | -0.122 | -0.6381 | Yes | ||
168 | GRB2 | 6650398 | 16274 | -0.122 | -0.6353 | Yes | ||
169 | SLC6A9 | 2470520 | 16327 | -0.128 | -0.6350 | Yes | ||
170 | KIF3A | 5050348 6650079 | 16372 | -0.133 | -0.6341 | Yes | ||
171 | STAT4 | 1660373 3130019 | 16416 | -0.138 | -0.6331 | Yes | ||
172 | YAF2 | 940053 | 16441 | -0.141 | -0.6310 | Yes | ||
173 | RTF1 | 2100735 | 16452 | -0.143 | -0.6280 | Yes | ||
174 | ARHGEF18 | 2120279 | 16514 | -0.152 | -0.6276 | Yes | ||
175 | SIPA1L2 | 4850731 | 16585 | -0.163 | -0.6274 | Yes | ||
176 | CDC14A | 4050132 | 16605 | -0.167 | -0.6244 | Yes | ||
177 | DNAJC13 | 4730091 | 16770 | -0.190 | -0.6287 | Yes | ||
178 | ARNTL | 3170463 | 16863 | -0.209 | -0.6286 | Yes | ||
179 | SIRT1 | 1190731 | 16889 | -0.212 | -0.6248 | Yes | ||
180 | MIB1 | 3800537 | 16919 | -0.217 | -0.6210 | Yes | ||
181 | ATP6V1B2 | 4060528 | 17018 | -0.234 | -0.6206 | Yes | ||
182 | SLC23A2 | 6660722 | 17066 | -0.245 | -0.6172 | Yes | ||
183 | SLC20A1 | 6420014 | 17078 | -0.248 | -0.6118 | Yes | ||
184 | ANKFY1 | 360309 5390021 | 17116 | -0.256 | -0.6075 | Yes | ||
185 | RBMS1 | 6400014 | 17139 | -0.261 | -0.6024 | Yes | ||
186 | YTHDF2 | 4060332 4610279 | 17187 | -0.271 | -0.5983 | Yes | ||
187 | MECP2 | 1940450 | 17253 | -0.290 | -0.5948 | Yes | ||
188 | PLAGL2 | 1770148 | 17310 | -0.305 | -0.5904 | Yes | ||
189 | FKBP5 | 2190048 | 17334 | -0.315 | -0.5839 | Yes | ||
190 | CCNE2 | 3120537 | 17335 | -0.315 | -0.5762 | Yes | ||
191 | H2AFZ | 1470168 | 17407 | -0.332 | -0.5720 | Yes | ||
192 | PPP1R15B | 2640280 5860082 | 17409 | -0.333 | -0.5639 | Yes | ||
193 | CSNK1G3 | 110450 | 17530 | -0.364 | -0.5616 | Yes | ||
194 | YWHAG | 3780341 | 17650 | -0.409 | -0.5581 | Yes | ||
195 | MAP2K4 | 5130133 | 17762 | -0.449 | -0.5531 | Yes | ||
196 | RNF44 | 5910692 | 17794 | -0.461 | -0.5436 | Yes | ||
197 | OSBPL11 | 1770044 | 17822 | -0.475 | -0.5335 | Yes | ||
198 | ATP1B1 | 3130594 | 17850 | -0.483 | -0.5231 | Yes | ||
199 | ATP6V1A | 6590242 | 17877 | -0.493 | -0.5125 | Yes | ||
200 | RUNX1 | 3840711 | 18014 | -0.563 | -0.5062 | Yes | ||
201 | SUPT6H | 3170082 | 18025 | -0.568 | -0.4928 | Yes | ||
202 | CDV3 | 1940577 | 18053 | -0.586 | -0.4800 | Yes | ||
203 | MTPN | 3940167 | 18102 | -0.614 | -0.4676 | Yes | ||
204 | APRIN | 2810050 | 18163 | -0.652 | -0.4550 | Yes | ||
205 | TRAM1 | 2340441 6620592 | 18164 | -0.652 | -0.4391 | Yes | ||
206 | OGT | 2360131 4610333 | 18167 | -0.653 | -0.4232 | Yes | ||
207 | WSB1 | 870563 | 18210 | -0.681 | -0.4089 | Yes | ||
208 | CD47 | 1850603 | 18238 | -0.703 | -0.3932 | Yes | ||
209 | PPP2CA | 3990113 | 18255 | -0.725 | -0.3764 | Yes | ||
210 | PITPNB | 5130039 | 18275 | -0.747 | -0.3592 | Yes | ||
211 | RAP2C | 1690132 | 18334 | -0.799 | -0.3428 | Yes | ||
212 | SFPQ | 4760110 | 18340 | -0.806 | -0.3234 | Yes | ||
213 | PDCD4 | 3360403 5690110 | 18370 | -0.850 | -0.3043 | Yes | ||
214 | MBNL1 | 2640762 7100048 | 18381 | -0.865 | -0.2837 | Yes | ||
215 | RABGAP1 | 5050397 | 18384 | -0.869 | -0.2626 | Yes | ||
216 | ANP32E | 6510706 | 18393 | -0.876 | -0.2417 | Yes | ||
217 | TCF12 | 3610324 7000156 | 18397 | -0.880 | -0.2203 | Yes | ||
218 | HOXB4 | 540131 | 18409 | -0.901 | -0.1989 | Yes | ||
219 | PRKACB | 4210170 | 18473 | -1.046 | -0.1768 | Yes | ||
220 | TFRC | 4050551 | 18490 | -1.089 | -0.1511 | Yes | ||
221 | CUL3 | 1850520 | 18514 | -1.160 | -0.1241 | Yes | ||
222 | DOLPP1 | 4780619 6400053 | 18517 | -1.172 | -0.0956 | Yes | ||
223 | BRD3 | 6130672 | 18526 | -1.239 | -0.0658 | Yes | ||
224 | TULP4 | 2320364 | 18549 | -1.415 | -0.0324 | Yes | ||
225 | ATP2A2 | 1090075 3990279 | 18554 | -1.475 | 0.0034 | Yes |