Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | -0.6760436 |
Normalized Enrichment Score (NES) | -1.8764968 |
Nominal p-value | 0.0 |
FDR q-value | 8.773886E-4 |
FWER p-Value | 0.0010 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | UBE2Q1 | 610348 2350114 4210717 | 222 | 1.001 | 0.0102 | No | ||
2 | PMP22 | 4010239 6550072 | 721 | 0.499 | -0.0057 | No | ||
3 | LRIG1 | 1050136 | 904 | 0.432 | -0.0060 | No | ||
4 | USP21 | 3060446 | 1283 | 0.338 | -0.0190 | No | ||
5 | SLC25A26 | 4210577 | 1353 | 0.324 | -0.0156 | No | ||
6 | IRF7 | 1570605 | 1645 | 0.268 | -0.0254 | No | ||
7 | HNRPA0 | 2680048 | 1767 | 0.251 | -0.0264 | No | ||
8 | ATP5A1 | 1990722 | 1999 | 0.217 | -0.0341 | No | ||
9 | ANTXR1 | 1990593 2850056 | 2002 | 0.217 | -0.0294 | No | ||
10 | ANKRD50 | 870543 | 2013 | 0.214 | -0.0252 | No | ||
11 | HIC2 | 4010433 | 2259 | 0.182 | -0.0345 | No | ||
12 | OTUB1 | 610551 | 2318 | 0.174 | -0.0338 | No | ||
13 | DOCK9 | 5080037 | 2337 | 0.172 | -0.0309 | No | ||
14 | EFNA3 | 6370390 | 2506 | 0.152 | -0.0367 | No | ||
15 | CRSP7 | 4230408 | 2561 | 0.147 | -0.0363 | No | ||
16 | VGLL4 | 6860463 | 2650 | 0.137 | -0.0381 | No | ||
17 | VAMP2 | 2100100 | 2701 | 0.131 | -0.0379 | No | ||
18 | ATAD2 | 870242 2260687 | 2707 | 0.131 | -0.0352 | No | ||
19 | CHKB | 770129 | 2931 | 0.112 | -0.0449 | No | ||
20 | LRP12 | 2370112 | 3109 | 0.100 | -0.0523 | No | ||
21 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 3151 | 0.097 | -0.0523 | No | ||
22 | TMEM16D | 2650324 | 3255 | 0.090 | -0.0559 | No | ||
23 | KPNA4 | 510369 | 3406 | 0.081 | -0.0623 | No | ||
24 | OVOL1 | 1690131 | 3661 | 0.070 | -0.0745 | No | ||
25 | SPRYD3 | 50403 | 3668 | 0.069 | -0.0733 | No | ||
26 | SPAG8 | 4280446 | 3829 | 0.063 | -0.0806 | No | ||
27 | FGF13 | 630575 1570440 5360121 | 3845 | 0.063 | -0.0800 | No | ||
28 | SNRP70 | 4200181 | 3902 | 0.060 | -0.0817 | No | ||
29 | GABRG2 | 2350402 4210204 6130279 6550037 | 3954 | 0.059 | -0.0832 | No | ||
30 | AFF3 | 3870102 | 4130 | 0.053 | -0.0915 | No | ||
31 | ZMYND19 | 1570706 6860551 | 4137 | 0.053 | -0.0907 | No | ||
32 | UNC5A | 2120528 3060324 | 4149 | 0.053 | -0.0901 | No | ||
33 | TBC1D4 | 6420397 | 4151 | 0.053 | -0.0890 | No | ||
34 | RNF38 | 1940746 3140133 3840601 | 4305 | 0.048 | -0.0962 | No | ||
35 | TRPS1 | 870100 | 4366 | 0.047 | -0.0984 | No | ||
36 | GAD1 | 2360035 3140167 | 4623 | 0.041 | -0.1115 | No | ||
37 | JPH1 | 610739 | 4713 | 0.039 | -0.1154 | No | ||
38 | VPS13D | 2350451 | 4772 | 0.038 | -0.1177 | No | ||
39 | CITED2 | 5670114 5130088 | 4868 | 0.036 | -0.1221 | No | ||
40 | PPP2R5C | 3310121 6650672 | 4881 | 0.036 | -0.1219 | No | ||
41 | SNAI1 | 6590253 | 4929 | 0.035 | -0.1237 | No | ||
42 | HIVEP2 | 6520538 | 4959 | 0.035 | -0.1245 | No | ||
43 | MAST1 | 6940215 | 5015 | 0.033 | -0.1268 | No | ||
44 | CDH2 | 520435 2450451 2760025 6650477 | 5382 | 0.028 | -0.1460 | No | ||
45 | SDC2 | 1980168 | 5559 | 0.026 | -0.1550 | No | ||
46 | CDH13 | 5130368 5340114 | 5585 | 0.025 | -0.1558 | No | ||
47 | TRAM2 | 3940112 | 5709 | 0.024 | -0.1620 | No | ||
48 | DLL1 | 1770377 | 5809 | 0.023 | -0.1669 | No | ||
49 | SOX21 | 1050110 4670041 6660338 | 5812 | 0.023 | -0.1665 | No | ||
50 | PDGFC | 4200133 | 5889 | 0.022 | -0.1701 | No | ||
51 | MARK1 | 450484 | 6011 | 0.021 | -0.1762 | No | ||
52 | AK5 | 6290348 | 6061 | 0.020 | -0.1784 | No | ||
53 | IL1A | 3610056 | 6101 | 0.020 | -0.1801 | No | ||
54 | NXPH1 | 3870546 | 6109 | 0.020 | -0.1801 | No | ||
55 | JUN | 840170 | 6162 | 0.019 | -0.1825 | No | ||
56 | POU4F1 | 2260315 | 6280 | 0.018 | -0.1884 | No | ||
57 | COBLL1 | 4230056 6370494 | 6441 | 0.017 | -0.1967 | No | ||
58 | HS3ST3B1 | 380040 | 6504 | 0.016 | -0.1997 | No | ||
59 | GRM5 | 60528 | 6513 | 0.016 | -0.1998 | No | ||
60 | CUL5 | 450142 | 6562 | 0.016 | -0.2021 | No | ||
61 | UBE2V2 | 4210484 | 6741 | 0.015 | -0.2114 | No | ||
62 | FZD4 | 1580520 | 6939 | 0.014 | -0.2218 | No | ||
63 | GAB1 | 2970156 | 7129 | 0.012 | -0.2318 | No | ||
64 | PTPN12 | 2030309 6020725 6130746 6290609 | 7211 | 0.012 | -0.2359 | No | ||
65 | FHOD3 | 1240541 | 7215 | 0.012 | -0.2358 | No | ||
66 | MEF2C | 670025 780338 | 7333 | 0.011 | -0.2419 | No | ||
67 | ZBTB11 | 6520092 | 7336 | 0.011 | -0.2418 | No | ||
68 | CAPN3 | 1980451 6940047 | 7344 | 0.011 | -0.2419 | No | ||
69 | CDH11 | 1230133 2100180 4610110 | 7630 | 0.010 | -0.2572 | No | ||
70 | TMEFF1 | 2680100 | 7775 | 0.009 | -0.2648 | No | ||
71 | SV2B | 3850717 | 7817 | 0.009 | -0.2668 | No | ||
72 | ENAH | 1690292 5700300 | 7886 | 0.009 | -0.2703 | No | ||
73 | IRX3 | 4200112 | 7975 | 0.009 | -0.2749 | No | ||
74 | BASP1 | 5700044 | 8224 | 0.008 | -0.2882 | No | ||
75 | LRRTM3 | 4210021 | 8321 | 0.007 | -0.2933 | No | ||
76 | NRXN3 | 1400546 3360471 | 8385 | 0.007 | -0.2966 | No | ||
77 | SRPX | 580717 1980162 | 8408 | 0.007 | -0.2976 | No | ||
78 | TTN | 2320161 4670056 6550026 | 8482 | 0.007 | -0.3014 | No | ||
79 | PSD2 | 2060091 | 8507 | 0.007 | -0.3026 | No | ||
80 | BCOR | 1660452 3940053 | 8572 | 0.006 | -0.3059 | No | ||
81 | FIGN | 7000601 | 8600 | 0.006 | -0.3073 | No | ||
82 | WDFY3 | 3610041 4560333 4570273 | 8653 | 0.006 | -0.3099 | No | ||
83 | EPHA7 | 1190288 4010278 | 8914 | 0.005 | -0.3240 | No | ||
84 | CSNK1A1 | 2340427 | 8950 | 0.005 | -0.3258 | No | ||
85 | CRSP6 | 2940358 | 8963 | 0.005 | -0.3263 | No | ||
86 | DKK2 | 3610433 | 9026 | 0.005 | -0.3296 | No | ||
87 | CPNE8 | 7040039 | 9158 | 0.004 | -0.3366 | No | ||
88 | RIMS3 | 3890563 | 9234 | 0.004 | -0.3406 | No | ||
89 | EYA1 | 1450278 5220390 | 9394 | 0.004 | -0.3491 | No | ||
90 | PIK3R1 | 4730671 | 9416 | 0.004 | -0.3502 | No | ||
91 | SNX9 | 3290592 | 9594 | 0.003 | -0.3597 | No | ||
92 | SERTAD2 | 2810673 6840450 | 9608 | 0.003 | -0.3604 | No | ||
93 | PDZRN3 | 2340131 | 9662 | 0.003 | -0.3632 | No | ||
94 | ESRRG | 4010181 | 9935 | 0.002 | -0.3779 | No | ||
95 | ARHGAP5 | 2510619 3360035 | 9967 | 0.002 | -0.3796 | No | ||
96 | BHLHB3 | 3450438 | 9995 | 0.002 | -0.3810 | No | ||
97 | ZIC1 | 670113 | 10040 | 0.002 | -0.3833 | No | ||
98 | SP4 | 3850176 | 10068 | 0.002 | -0.3848 | No | ||
99 | ADAM10 | 3780156 | 10223 | 0.001 | -0.3931 | No | ||
100 | RPE | 940114 | 10326 | 0.001 | -0.3986 | No | ||
101 | NDST1 | 1500427 5340121 | 10735 | -0.000 | -0.4208 | No | ||
102 | SP3 | 3840338 | 10972 | -0.001 | -0.4336 | No | ||
103 | SS18 | 1940440 2900072 6900129 | 11119 | -0.001 | -0.4415 | No | ||
104 | PCDH18 | 430010 | 11197 | -0.001 | -0.4457 | No | ||
105 | KCNMA1 | 1450402 | 11220 | -0.001 | -0.4468 | No | ||
106 | DACH1 | 2450593 5700592 | 11221 | -0.001 | -0.4468 | No | ||
107 | NLGN3 | 2650463 | 11240 | -0.001 | -0.4478 | No | ||
108 | NLGN1 | 5670278 | 11290 | -0.002 | -0.4504 | No | ||
109 | BHLHB5 | 6510520 | 11355 | -0.002 | -0.4538 | No | ||
110 | UNC50 | 4920037 | 11547 | -0.002 | -0.4642 | No | ||
111 | PUM2 | 4200441 5910446 | 11602 | -0.003 | -0.4670 | No | ||
112 | SALL1 | 5420020 7050195 | 11659 | -0.003 | -0.4700 | No | ||
113 | GABRA1 | 130372 | 11904 | -0.004 | -0.4832 | No | ||
114 | ZIC2 | 1410408 | 11940 | -0.004 | -0.4850 | No | ||
115 | KCNIP4 | 4120435 7050605 | 11948 | -0.004 | -0.4853 | No | ||
116 | GABRA5 | 5570215 | 12028 | -0.004 | -0.4895 | No | ||
117 | THRAP1 | 2470121 | 12174 | -0.005 | -0.4973 | No | ||
118 | TNFSF11 | 6350204 | 12531 | -0.006 | -0.5165 | No | ||
119 | GPC4 | 5910408 | 12545 | -0.006 | -0.5171 | No | ||
120 | OSBPL6 | 3800072 | 12558 | -0.006 | -0.5176 | No | ||
121 | SPEN | 2060041 | 12606 | -0.006 | -0.5200 | No | ||
122 | DUSP16 | 2370082 2480450 | 13178 | -0.009 | -0.5509 | No | ||
123 | PFN2 | 730040 5700026 | 13308 | -0.010 | -0.5576 | No | ||
124 | SEMA4C | 1980315 | 13389 | -0.011 | -0.5617 | No | ||
125 | HIPK1 | 110193 | 13664 | -0.013 | -0.5764 | No | ||
126 | WNT5A | 840685 3120152 | 13766 | -0.014 | -0.5815 | No | ||
127 | PIP5K3 | 5360112 | 13770 | -0.014 | -0.5814 | No | ||
128 | PBX3 | 1300424 3710577 6180575 | 13851 | -0.015 | -0.5854 | No | ||
129 | RSBN1 | 7000487 | 13919 | -0.016 | -0.5887 | No | ||
130 | KIF1B | 1240494 2370139 4570270 6510102 | 13933 | -0.016 | -0.5891 | No | ||
131 | SORCS3 | 5700309 | 13960 | -0.016 | -0.5901 | No | ||
132 | TJP1 | 6350184 | 14069 | -0.017 | -0.5956 | No | ||
133 | PCGF2 | 6370347 | 14132 | -0.018 | -0.5986 | No | ||
134 | SPRED2 | 510138 540195 | 14186 | -0.019 | -0.6010 | No | ||
135 | CCNT2 | 2100390 4150563 | 14196 | -0.019 | -0.6011 | No | ||
136 | NAB1 | 430739 1230114 3390736 6660056 | 14405 | -0.022 | -0.6119 | No | ||
137 | THRAP2 | 4920600 | 14429 | -0.023 | -0.6126 | No | ||
138 | SSH2 | 360056 | 14520 | -0.024 | -0.6170 | No | ||
139 | EIF2C1 | 6900551 | 14712 | -0.029 | -0.6267 | No | ||
140 | JARID1B | 4730494 | 14735 | -0.030 | -0.6273 | No | ||
141 | RBM12 | 4570239 6040411 6660129 | 14783 | -0.031 | -0.6291 | No | ||
142 | TLE4 | 1450064 1500519 | 14795 | -0.031 | -0.6291 | No | ||
143 | HEMGN | 670411 | 14922 | -0.035 | -0.6351 | No | ||
144 | CLASP1 | 6860279 | 15001 | -0.037 | -0.6385 | No | ||
145 | RALGPS1 | 3440129 6400746 | 15035 | -0.039 | -0.6395 | No | ||
146 | BAZ2A | 730184 | 15091 | -0.041 | -0.6416 | No | ||
147 | E2F6 | 3120133 3850332 4070324 | 15213 | -0.046 | -0.6471 | No | ||
148 | SH2D3C | 3060014 | 15296 | -0.049 | -0.6505 | No | ||
149 | GTF2IRD1 | 2030154 3990040 5080372 | 15300 | -0.049 | -0.6495 | No | ||
150 | AXIN1 | 3360358 6940451 | 15348 | -0.051 | -0.6510 | No | ||
151 | RPS6KA5 | 2120563 7040546 | 15421 | -0.055 | -0.6536 | No | ||
152 | AR | 6380167 | 15424 | -0.056 | -0.6525 | No | ||
153 | FBS1 | 2570520 | 15487 | -0.060 | -0.6546 | No | ||
154 | PHF12 | 870400 3130687 | 15495 | -0.060 | -0.6536 | No | ||
155 | SPIRE2 | 450088 | 15621 | -0.068 | -0.6589 | No | ||
156 | ANKRD17 | 2120402 3850035 6400044 | 15654 | -0.070 | -0.6591 | No | ||
157 | PDE4D | 2470528 6660014 | 15736 | -0.076 | -0.6618 | No | ||
158 | UBE3A | 1240152 2690438 5860609 | 15786 | -0.080 | -0.6627 | No | ||
159 | GNB1 | 2120397 | 15968 | -0.093 | -0.6704 | No | ||
160 | CARM1 | 7040292 | 15993 | -0.096 | -0.6696 | No | ||
161 | XPO7 | 2630215 6760014 | 16017 | -0.097 | -0.6687 | No | ||
162 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 16029 | -0.099 | -0.6671 | No | ||
163 | ARFGEF1 | 6760494 | 16081 | -0.103 | -0.6676 | No | ||
164 | FOXO1A | 3120670 | 16096 | -0.104 | -0.6660 | No | ||
165 | MAPK1 | 3190193 6200253 | 16153 | -0.109 | -0.6666 | No | ||
166 | MADD | 6100725 7000088 | 16165 | -0.111 | -0.6648 | No | ||
167 | RBBP6 | 2320129 | 16186 | -0.113 | -0.6633 | No | ||
168 | FBXO33 | 1510504 | 16211 | -0.115 | -0.6621 | No | ||
169 | MLLT10 | 1410288 3290142 | 16332 | -0.128 | -0.6657 | No | ||
170 | NUDT4 | 6760689 | 16500 | -0.150 | -0.6715 | No | ||
171 | SIPA1L2 | 4850731 | 16585 | -0.163 | -0.6724 | Yes | ||
172 | CDC14A | 4050132 | 16605 | -0.167 | -0.6697 | Yes | ||
173 | DCUN1D1 | 2360332 | 16631 | -0.171 | -0.6673 | Yes | ||
174 | RYBP | 60746 | 16733 | -0.184 | -0.6687 | Yes | ||
175 | EFTUD1 | 5360736 | 16741 | -0.185 | -0.6650 | Yes | ||
176 | DNAJC13 | 4730091 | 16770 | -0.190 | -0.6622 | Yes | ||
177 | FMNL2 | 4060438 | 16817 | -0.199 | -0.6603 | Yes | ||
178 | PDPK1 | 6650168 | 16837 | -0.204 | -0.6568 | Yes | ||
179 | PHF2 | 4060300 | 16869 | -0.210 | -0.6538 | Yes | ||
180 | ITGB1 | 5080156 6270528 | 16877 | -0.211 | -0.6495 | Yes | ||
181 | CDC73 | 1580132 | 16908 | -0.216 | -0.6463 | Yes | ||
182 | UTX | 2900017 6770452 | 16924 | -0.218 | -0.6423 | Yes | ||
183 | KBTBD2 | 2320014 | 16953 | -0.223 | -0.6388 | Yes | ||
184 | EIF4ENIF1 | 2060341 | 17000 | -0.232 | -0.6362 | Yes | ||
185 | CUGBP2 | 6180121 6840139 | 17086 | -0.249 | -0.6353 | Yes | ||
186 | ITSN2 | 780484 | 17294 | -0.301 | -0.6398 | Yes | ||
187 | PAIP1 | 3870576 | 17315 | -0.308 | -0.6341 | Yes | ||
188 | CREBBP | 5690035 7040050 | 17381 | -0.327 | -0.6303 | Yes | ||
189 | NCOA1 | 3610438 | 17461 | -0.346 | -0.6269 | Yes | ||
190 | IRF2 | 5390044 | 17618 | -0.397 | -0.6266 | Yes | ||
191 | DDX3X | 2190020 | 17682 | -0.421 | -0.6206 | Yes | ||
192 | NMT1 | 5810152 | 17748 | -0.444 | -0.6143 | Yes | ||
193 | CTDSPL | 4670546 | 17755 | -0.447 | -0.6047 | Yes | ||
194 | SFRS3 | 770315 4230593 | 17806 | -0.468 | -0.5970 | Yes | ||
195 | SIN3A | 2190121 | 17828 | -0.476 | -0.5875 | Yes | ||
196 | BCL7A | 4560095 | 17881 | -0.495 | -0.5793 | Yes | ||
197 | MBNL2 | 3450707 | 17905 | -0.509 | -0.5693 | Yes | ||
198 | ZFX | 5900400 | 17969 | -0.540 | -0.5607 | Yes | ||
199 | MTPN | 3940167 | 18102 | -0.614 | -0.5542 | Yes | ||
200 | PPP3CB | 6020156 | 18136 | -0.635 | -0.5419 | Yes | ||
201 | DHX36 | 2470465 | 18180 | -0.659 | -0.5295 | Yes | ||
202 | UBE2G1 | 2230546 5420528 7040463 | 18213 | -0.683 | -0.5161 | Yes | ||
203 | RHOT1 | 6760692 | 18289 | -0.763 | -0.5032 | Yes | ||
204 | DAB2IP | 3170064 6200441 | 18308 | -0.779 | -0.4868 | Yes | ||
205 | ETF1 | 6770075 | 18309 | -0.780 | -0.4695 | Yes | ||
206 | PIAS1 | 5340301 | 18311 | -0.780 | -0.4522 | Yes | ||
207 | SRPK2 | 6380341 | 18312 | -0.780 | -0.4348 | Yes | ||
208 | AP3S1 | 5570044 | 18319 | -0.785 | -0.4177 | Yes | ||
209 | BRD7 | 2120068 6200746 | 18343 | -0.812 | -0.4009 | Yes | ||
210 | KLF3 | 5130438 | 18345 | -0.818 | -0.3828 | Yes | ||
211 | CLPX | 6220156 | 18357 | -0.838 | -0.3647 | Yes | ||
212 | TBK1 | 5690338 | 18385 | -0.870 | -0.3468 | Yes | ||
213 | APLP2 | 3610037 | 18405 | -0.895 | -0.3280 | Yes | ||
214 | MCL1 | 1660672 | 18432 | -0.934 | -0.3086 | Yes | ||
215 | PPP2R5D | 4010156 380408 5550112 5670162 | 18449 | -0.968 | -0.2879 | Yes | ||
216 | TTC7B | 4760725 | 18488 | -1.077 | -0.2660 | Yes | ||
217 | HMGCS1 | 6620452 | 18507 | -1.134 | -0.2418 | Yes | ||
218 | PPP1R10 | 110136 3170725 3610484 | 18539 | -1.334 | -0.2138 | Yes | ||
219 | ATP2A2 | 1090075 3990279 | 18554 | -1.475 | -0.1817 | Yes | ||
220 | BTG1 | 4200735 6040131 6200133 | 18596 | -1.988 | -0.1397 | Yes | ||
221 | ARID1A | 2630022 1690551 4810110 | 18616 | -6.327 | 0.0000 | Yes |