Details for gene set REACTOME_SIGNALING_BY

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	truncNotch
GeneSet	REACTOME_SIGNALING_BY_GPCR
Enrichment Score (ES)	0.64250535
Normalized Enrichment Score (NES)	1.6273884
Nominal p-value	0.0
FDR q-value	0.21567382
FWER p-Value	0.619

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GAL	3930279	9	3.618	0.1882	Yes
2	RHOA	580142 5900131 5340450	11	3.476	0.3695	Yes
3	GNAS	630441 1850373 4050152	19	2.879	0.5192	Yes
4	P2RY6	5290400	393	0.737	0.5375	Yes
5	ADRB2	3290373	402	0.728	0.5750	Yes
6	RHOG	6760575	684	0.516	0.5867	Yes
7	GNA12	1230301	737	0.495	0.6097	Yes
8	CCR7	2060687	763	0.484	0.6336	Yes
9	CNR2	2760398	1061	0.381	0.6375	Yes
10	TBXA2R	2370292 3940066	1293	0.337	0.6425	Yes
11	CCL5	3710397	1721	0.258	0.6328	No
12	GNG2	2230390	1814	0.243	0.6405	No
13	F2	5720280	2123	0.199	0.6343	No
14	ADRBK1	1340333	2249	0.183	0.6370	No
15	PDYN	5720408	2370	0.167	0.6393	No
16	EDNRA	6900133	2598	0.143	0.6345	No
17	HRH2	3840440	3516	0.076	0.5888	No
18	BDKRB1	730592	3541	0.075	0.5914	No
19	GCGR	6620497	3580	0.073	0.5931	No
20	NTSR1	6510136	3658	0.070	0.5926	No
21	CRHR2	4590672	3772	0.065	0.5899	No
22	GNAZ	6130296	3892	0.061	0.5866	No
23	AVPR2	360064	3895	0.060	0.5897	No
24	ADORA2A	1990687	3929	0.059	0.5910	No
25	ADCYAP1R1	3390020 4280184 5360180	4067	0.055	0.5865	No
26	GRM6	2030398	4213	0.051	0.5812	No
27	CX3CL1	3990707	4394	0.046	0.5739	No
28	LTB4R	1770056	4603	0.041	0.5648	No
29	HTR2A	360037 6330255	4780	0.038	0.5572	No
30	AGT	7000575	4988	0.034	0.5478	No
31	AVP	2100113	4998	0.034	0.5491	No
32	GRK5	1940348 4670053	5087	0.032	0.5460	No
33	GNAQ	430670 4210131 5900736	5173	0.031	0.5430	No
34	GLP1R	6420528	5201	0.031	0.5432	No
35	GLP2R	4150577 5290273 7050095	5226	0.030	0.5434	No
36	PTGIR	2100563	5230	0.030	0.5449	No
37	GHRHR	3130500 4010154	5692	0.024	0.5211	No
38	P2RY14	6100497	5775	0.023	0.5179	No
39	GPR17	5890671	5867	0.022	0.5142	No
40	TSHB	6770500	5963	0.021	0.5101	No
41	SCTR	2940070	5967	0.021	0.5111	No
42	CALCRL	4280035	5969	0.021	0.5121	No
43	IAPP	4230040	5972	0.021	0.5131	No
44	P2RY1	6040121	6025	0.021	0.5113	No
45	KNG1	6400576 6770347	6084	0.020	0.5093	No
46	FSHR	610041 7040121	6157	0.019	0.5064	No
47	GNAT1	5270048 6100170	6176	0.019	0.5064	No
48	MC5R	2640176	6284	0.018	0.5016	No
49	PTGDR	3850161	6297	0.018	0.5019	No
50	AGTR1	4780524 2680592	6306	0.018	0.5024	No
51	FSHB	7100592	6350	0.018	0.5010	No
52	XCR1	5080072	6692	0.015	0.4833	No
53	CCKBR	2760128	6896	0.014	0.4730	No
54	DRD3	4780402	7048	0.013	0.4655	No
55	CHRM2	870750	7089	0.013	0.4640	No
56	CHRM5	5390333	7197	0.012	0.4589	No
57	HCRTR2	2350463	7286	0.012	0.4547	No
58	PPYR1	1410072	7328	0.011	0.4531	No
59	ADORA1	6370520	7575	0.010	0.4403	No
60	IL8RA	1580100	7607	0.010	0.4392	No
61	ADM2	4060102	7683	0.010	0.4356	No
62	P2RY4	630053	7765	0.009	0.4317	No
63	CALCR	1690494	7822	0.009	0.4292	No
64	MC2R	2970504	7874	0.009	0.4269	No
65	HCRTR1	1580273	7895	0.009	0.4263	No
66	HRH1	840100	7935	0.009	0.4246	No
67	HTR6	4850022	8142	0.008	0.4139	No
68	CASR	610504	8366	0.007	0.4022	No
69	BAI3	940692	8550	0.006	0.3926	No
70	GPRC6A	4560576	8574	0.006	0.3917	No
71	DARC	3940050	8640	0.006	0.3885	No
72	OPRM1	5360279	8737	0.006	0.3836	No
73	GNGT1	5220156	8845	0.005	0.3781	No
74	PTGFR	3850373	8955	0.005	0.3724	No
75	CCR3	50427	8997	0.005	0.3705	No
76	OXT	3850692	9042	0.005	0.3683	No
77	CALCA	5860167	9172	0.004	0.3616	No
78	PIK3R1	4730671	9416	0.004	0.3486	No
79	ADRA2A	5340520	9678	0.003	0.3347	No
80	HCRT	2970463	10328	0.001	0.2996	No
81	PPY	2340373	10388	0.001	0.2964	No
82	NPFF	2030280	10541	0.001	0.2882	No
83	CCR10	4050097	10634	0.000	0.2833	No
84	TACR1	70358 3840411	10741	-0.000	0.2775	No
85	DRD1	430025	10805	-0.000	0.2742	No
86	C5AR1	4540402	10869	-0.000	0.2708	No
87	CGA	630403	10967	-0.001	0.2656	No
88	VIPR2	6520050	11060	-0.001	0.2606	No
89	AKT1	5290746	11364	-0.002	0.2443	No
90	SCT	2230348	11473	-0.002	0.2386	No
91	TACR3	4780017	11510	-0.002	0.2367	No
92	CRH	3710301	11641	-0.003	0.2298	No
93	TACR2	1740358	11762	-0.003	0.2235	No
94	IL8RB	450592 1170537	11796	-0.003	0.2219	No
95	PTGER1	6100132	11871	-0.003	0.2181	No
96	PTGER3	2900739 6770750	11977	-0.004	0.2126	No
97	EDN1	1770047	12016	-0.004	0.2107	No
98	TSHR	1190687 5270364	12131	-0.004	0.2048	No
99	CCR6	5720368 6020176	12251	-0.005	0.1986	No
100	GRPR	6020170	12272	-0.005	0.1978	No
101	MTNR1A	380204	12324	-0.005	0.1953	No
102	OPN1SW	6420377	12355	-0.005	0.1939	No
103	GIP	3170364	12424	-0.006	0.1906	No
104	GALR1	6020452	12482	-0.006	0.1878	No
105	HTR1F	670148	12616	-0.006	0.1809	No
106	LHB	1450368	12682	-0.007	0.1777	No
107	XCL1	3800504	12744	-0.007	0.1748	No
108	NTS	380300 2120592	12776	-0.007	0.1735	No
109	SST	6590142	12786	-0.007	0.1734	No
110	TAC1	7000195 380706	12833	-0.007	0.1713	No
111	GNA14	3390017	12941	-0.008	0.1659	No
112	CCK	6370368	12965	-0.008	0.1651	No
113	VIP	2850647	13050	-0.009	0.1610	No
114	GHRH	4570575	13059	-0.009	0.1610	No
115	LHCGR	4560465 5860551	13296	-0.010	0.1488	No
116	CXCL11	1090551	13390	-0.011	0.1443	No
117	AVPR1A	2120300	13659	-0.013	0.1305	No
118	CCL25	450541 540435	13809	-0.014	0.1232	No
119	GCG	6220735	13940	-0.016	0.1169	No
120	PIK3CA	6220129	13948	-0.016	0.1174	No
121	ADCYAP1	520086	13965	-0.016	0.1174	No
122	PLCB2	360132	14047	-0.017	0.1139	No
123	CGB	580273	14234	-0.020	0.1048	No
124	KISS1	1580398	14542	-0.025	0.0895	No
125	CXCR6	3190440	14571	-0.026	0.0893	No
126	ADRA1D	380035 540025	14782	-0.031	0.0796	No
127	SSTR1	2630471	14971	-0.036	0.0713	No
128	PNOC	1990114	15353	-0.052	0.0533	No
129	ADCY6	450364 6290670 6940286	15563	-0.065	0.0454	No
130	NMB	3360735	15639	-0.069	0.0450	No
131	PDE4D	2470528 6660014	15736	-0.076	0.0437	No
132	PTGER2	3170039	15757	-0.078	0.0467	No
133	P2RY2	2640180 2810128	15885	-0.087	0.0443	No
134	GNB1	2120397	15968	-0.093	0.0448	No
135	RAMP1	2320168	16061	-0.101	0.0451	No
136	P2RY10	6370039 6840204	16343	-0.129	0.0366	No
137	F2R	4810180	16562	-0.159	0.0331	No
138	PDPK1	6650168	16837	-0.204	0.0289	No
139	PIK3CG	5890110	17262	-0.292	0.0212	No
140	GNA13	4590102	17781	-0.455	0.0169	No
141	ROCK1	130044	17976	-0.542	0.0346	No