Details for gene set REACTOME_DNA

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	REACTOME_DNA_REPLICATION
Enrichment Score (ES)	-0.6649625
Normalized Enrichment Score (NES)	-1.6122202
Nominal p-value	0.0024038462
FDR q-value	0.33285728
FWER p-Value	0.791

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PSMA1	380059 2760195	58	1.771	0.0767	No
2	PSMC1	6350538	834	0.457	0.0555	No
3	PSMD2	4670706 5050364	1184	0.356	0.0527	No
4	PSMD9	50020 5890368	1910	0.229	0.0239	No
5	RFC5	3800452 6020091	1934	0.225	0.0328	No
6	POLD1	4830026	2120	0.200	0.0318	No
7	PSMA7	2230131	2358	0.169	0.0267	No
8	LIG1	1980438 4540112 5570609	2620	0.140	0.0189	No
9	PSMB6	2690711	2844	0.118	0.0122	No
10	POLD2	6400148	3013	0.106	0.0079	No
11	MCM2	5050139	3062	0.103	0.0100	No
12	PSMB10	630504 6510039	3078	0.102	0.0137	No
13	MCM5	2680647	3628	0.071	-0.0127	No
14	PSMB3	4280594	3887	0.061	-0.0238	No
15	PSMA5	5390537	4502	0.044	-0.0550	No
16	MCM3	5570068	4864	0.036	-0.0728	No
17	POLA2	940519	4991	0.034	-0.0781	No
18	PSMB4	520402	5907	0.022	-0.1264	No
19	PSMB9	6980471	6277	0.018	-0.1455	No
20	RFC3	1980600	6368	0.018	-0.1495	No
21	PSMA3	5900047 7040161	8190	0.008	-0.2474	No
22	PSMC3	2480184	8313	0.007	-0.2536	No
23	PSMD5	3940139 4570041	8779	0.006	-0.2784	No
24	POLE2	6110041	9439	0.004	-0.3138	No
25	POLA1	4760541	9613	0.003	-0.3230	No
26	PSMA6	50609	10313	0.001	-0.3606	No
27	PSMD8	630142	11012	-0.001	-0.3982	No
28	PSMD11	2340538 6510053	13573	-0.012	-0.5357	No
29	MCM10	4920632	14437	-0.023	-0.5812	No
30	PSMB5	6290242	14459	-0.023	-0.5813	No
31	ORC2L	1990470 6510019	14531	-0.025	-0.5840	No
32	PSMC2	7040010	14539	-0.025	-0.5832	No
33	ORC1L	2370328 6110390	15055	-0.039	-0.6092	No
34	CDK2	130484 2260301 4010088 5050110	15285	-0.049	-0.6194	No
35	PSMB1	2940402	15414	-0.055	-0.6238	No
36	FEN1	1770541	15483	-0.059	-0.6248	No
37	RPA2	2760301 5420195	15573	-0.065	-0.6267	No
38	ORC4L	4230538 5550288	15863	-0.085	-0.6384	No
39	PSME3	2810537	15913	-0.089	-0.6370	No
40	PSMC6	2810021	16015	-0.097	-0.6381	No
41	MCM7	3290292 5220056	16086	-0.103	-0.6372	No
42	PSMC5	2760315 6550021	16184	-0.113	-0.6374	No
43	PSMD3	1400647	16442	-0.142	-0.6448	No
44	GMNN	2630148	16570	-0.161	-0.6444	No
45	PRIM1	6420746	16667	-0.175	-0.6417	No
46	PSMD4	430068	16899	-0.215	-0.6445	No
47	ORC5L	1940133 1940711	17097	-0.252	-0.6438	No
48	PSME1	450193 4480035	17491	-0.353	-0.6491	Yes
49	RPA3	5700136	17503	-0.356	-0.6336	Yes
50	PSMD12	730044	17531	-0.365	-0.6186	Yes
51	POLD3	6400278	17603	-0.388	-0.6050	Yes
52	RB1	5900338	17613	-0.394	-0.5877	Yes
53	PCNA	940754	17662	-0.414	-0.5717	Yes
54	PSMA2	6510093	17678	-0.420	-0.5536	Yes
55	RPA1	360452	17708	-0.427	-0.5359	Yes
56	POLE	6020538	17772	-0.451	-0.5190	Yes
57	PSMB2	940035 4210324	18031	-0.572	-0.5071	Yes
58	PSMA4	4560427	18051	-0.585	-0.4818	Yes
59	RFC1	1190673	18057	-0.589	-0.4555	Yes
60	PSMD7	2030619 6220594	18080	-0.604	-0.4294	Yes
61	PSMD14	5690593	18127	-0.630	-0.4035	Yes
62	PSMD10	520494 1170576 3830050	18182	-0.660	-0.3767	Yes
63	CDC45L	70537 3130114	18193	-0.667	-0.3472	Yes
64	E2F2	5270609 5570377 7000465	18260	-0.731	-0.3178	Yes
65	MCM6	60092 540181 6510110	18453	-0.990	-0.2836	Yes
66	PSMC4	580050 1580025	18506	-1.133	-0.2353	Yes
67	MCM4	2760673 5420711	18538	-1.324	-0.1773	Yes
68	RFC4	3800082 6840142	18540	-1.338	-0.1171	Yes
69	CDC7	4060546 4850041	18609	-2.689	0.0004	Yes