Details for gene set REACTOME_CELL_CYCLE

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	wtNotch
GeneSet	REACTOME_CELL_CYCLE_CHECKPOINTS
Enrichment Score (ES)	-0.6439006
Normalized Enrichment Score (NES)	-1.6122955
Nominal p-value	0.0023419203
FDR q-value	0.41554156
FWER p-Value	0.79

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PSMA1	380059 2760195	58	1.771	0.0792	No
2	PSMC1	6350538	834	0.457	0.0587	No
3	PSMD2	4670706 5050364	1184	0.356	0.0564	No
4	PSMD9	50020 5890368	1910	0.229	0.0280	No
5	RFC5	3800452 6020091	1934	0.225	0.0372	No
6	PSMA7	2230131	2358	0.169	0.0222	No
7	PSMB6	2690711	2844	0.118	0.0016	No
8	MCM2	5050139	3062	0.103	-0.0053	No
9	PSMB10	630504 6510039	3078	0.102	-0.0014	No
10	BUB3	3170546	3320	0.087	-0.0104	No
11	CDC20	3440017 3440044 6220088	3342	0.085	-0.0075	No
12	TP53	6130707	3540	0.075	-0.0147	No
13	MCM5	2680647	3628	0.071	-0.0161	No
14	PSMB3	4280594	3887	0.061	-0.0272	No
15	PSMA5	5390537	4502	0.044	-0.0583	No
16	MCM3	5570068	4864	0.036	-0.0760	No
17	RAD1	4200551	5030	0.033	-0.0834	No
18	UBE2C	6130017	5158	0.031	-0.0888	No
19	PSMB4	520402	5907	0.022	-0.1281	No
20	PSMB9	6980471	6277	0.018	-0.1472	No
21	RFC3	1980600	6368	0.018	-0.1512	No
22	PSMA3	5900047 7040161	8190	0.008	-0.2491	No
23	PSMC3	2480184	8313	0.007	-0.2553	No
24	PSMD5	3940139 4570041	8779	0.006	-0.2801	No
25	PSMA6	50609	10313	0.001	-0.3627	No
26	PSMD8	630142	11012	-0.001	-0.4004	No
27	UBE2D1	1850400	11163	-0.001	-0.4084	No
28	CCNB2	6510528	13033	-0.009	-0.5088	No
29	CHEK1	50167 1940300	13273	-0.010	-0.5212	No
30	CDKN1A	4050088 6400706	13471	-0.011	-0.5313	No
31	PSMD11	2340538 6510053	13573	-0.012	-0.5362	No
32	ATM	3610110 4050524	13898	-0.015	-0.5529	No
33	CDC25C	2570673 4760161 6520707	14329	-0.021	-0.5751	No
34	MCM10	4920632	14437	-0.023	-0.5798	No
35	PSMB5	6290242	14459	-0.023	-0.5799	No
36	ORC2L	1990470 6510019	14531	-0.025	-0.5826	No
37	PSMC2	7040010	14539	-0.025	-0.5818	No
38	WEE1	3390070	14671	-0.027	-0.5876	No
39	ORC1L	2370328 6110390	15055	-0.039	-0.6064	No
40	CDK2	130484 2260301 4010088 5050110	15285	-0.049	-0.6165	No
41	PSMB1	2940402	15414	-0.055	-0.6208	No
42	MDM2	3450053 5080138	15571	-0.065	-0.6262	No
43	RPA2	2760301 5420195	15573	-0.065	-0.6232	No
44	ORC4L	4230538 5550288	15863	-0.085	-0.6349	No
45	PSME3	2810537	15913	-0.089	-0.6334	No
46	HUS1	3440494 3800156	15954	-0.092	-0.6312	No
47	PSMC6	2810021	16015	-0.097	-0.6299	No
48	MCM7	3290292 5220056	16086	-0.103	-0.6289	No
49	CDC25A	3800184	16131	-0.107	-0.6263	No
50	PSMC5	2760315 6550021	16184	-0.113	-0.6239	No
51	RAD9B	2320064	16306	-0.126	-0.6245	No
52	PSMD3	1400647	16442	-0.142	-0.6252	No
53	CDC16	1940706	16789	-0.194	-0.6349	Yes
54	UBE2E1	4230064 1090440	16865	-0.209	-0.6292	Yes
55	PSMD4	430068	16899	-0.215	-0.6210	Yes
56	ORC5L	1940133 1940711	17097	-0.252	-0.6199	Yes
57	PSME1	450193 4480035	17491	-0.353	-0.6247	Yes
58	RPA3	5700136	17503	-0.356	-0.6087	Yes
59	PSMD12	730044	17531	-0.365	-0.5932	Yes
60	PSMA2	6510093	17678	-0.420	-0.5815	Yes
61	RPA1	360452	17708	-0.427	-0.5632	Yes
62	PSMB2	940035 4210324	18031	-0.572	-0.5540	Yes
63	MAD2L1	4480725	18047	-0.583	-0.5277	Yes
64	PSMA4	4560427	18051	-0.585	-0.5006	Yes
65	PSMD7	2030619 6220594	18080	-0.604	-0.4740	Yes
66	PSMD14	5690593	18127	-0.630	-0.4472	Yes
67	PSMD10	520494 1170576 3830050	18182	-0.660	-0.4194	Yes
68	CDC45L	70537 3130114	18193	-0.667	-0.3889	Yes
69	BUB1B	1450288	18215	-0.685	-0.3582	Yes
70	CCNB1	4590433 4780372	18216	-0.685	-0.3263	Yes
71	MCM6	60092 540181 6510110	18453	-0.990	-0.2930	Yes
72	PSMC4	580050 1580025	18506	-1.133	-0.2431	Yes
73	MCM4	2760673 5420711	18538	-1.324	-0.1832	Yes
74	RFC4	3800082 6840142	18540	-1.338	-0.1210	Yes
75	CDC7	4060546 4850041	18609	-2.689	0.0004	Yes