Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | -0.78591347 |
| Normalized Enrichment Score (NES) | -1.5954065 |
| Nominal p-value | 0.0024213076 |
| FDR q-value | 0.36186537 |
| FWER p-Value | 0.862 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RFC5 | 3800452 6020091 | 1934 | 0.225 | -0.0798 | No | ||
| 2 | MCM2 | 5050139 | 3062 | 0.103 | -0.1294 | No | ||
| 3 | MCM5 | 2680647 | 3628 | 0.071 | -0.1521 | No | ||
| 4 | MCM3 | 5570068 | 4864 | 0.036 | -0.2146 | No | ||
| 5 | RAD1 | 4200551 | 5030 | 0.033 | -0.2199 | No | ||
| 6 | RFC3 | 1980600 | 6368 | 0.018 | -0.2900 | No | ||
| 7 | CHEK1 | 50167 1940300 | 13273 | -0.010 | -0.6602 | No | ||
| 8 | CDC25C | 2570673 4760161 6520707 | 14329 | -0.021 | -0.7147 | No | ||
| 9 | MCM10 | 4920632 | 14437 | -0.023 | -0.7180 | No | ||
| 10 | ORC2L | 1990470 6510019 | 14531 | -0.025 | -0.7203 | No | ||
| 11 | ORC1L | 2370328 6110390 | 15055 | -0.039 | -0.7442 | No | ||
| 12 | CDK2 | 130484 2260301 4010088 5050110 | 15285 | -0.049 | -0.7512 | No | ||
| 13 | RPA2 | 2760301 5420195 | 15573 | -0.065 | -0.7597 | No | ||
| 14 | ORC4L | 4230538 5550288 | 15863 | -0.085 | -0.7660 | Yes | ||
| 15 | HUS1 | 3440494 3800156 | 15954 | -0.092 | -0.7609 | Yes | ||
| 16 | MCM7 | 3290292 5220056 | 16086 | -0.103 | -0.7568 | Yes | ||
| 17 | CDC25A | 3800184 | 16131 | -0.107 | -0.7476 | Yes | ||
| 18 | RAD9B | 2320064 | 16306 | -0.126 | -0.7434 | Yes | ||
| 19 | ORC5L | 1940133 1940711 | 17097 | -0.252 | -0.7588 | Yes | ||
| 20 | RPA3 | 5700136 | 17503 | -0.356 | -0.7422 | Yes | ||
| 21 | RPA1 | 360452 | 17708 | -0.427 | -0.7071 | Yes | ||
| 22 | CDC45L | 70537 3130114 | 18193 | -0.667 | -0.6612 | Yes | ||
| 23 | MCM6 | 60092 540181 6510110 | 18453 | -0.990 | -0.5684 | Yes | ||
| 24 | MCM4 | 2760673 5420711 | 18538 | -1.324 | -0.4301 | Yes | ||
| 25 | RFC4 | 3800082 6840142 | 18540 | -1.338 | -0.2860 | Yes | ||
| 26 | CDC7 | 4060546 4850041 | 18609 | -2.689 | 0.0004 | Yes |
