Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | UVC_HIGH_ALL_DN |
Enrichment Score (ES) | -0.5715846 |
Normalized Enrichment Score (NES) | -1.5705295 |
Nominal p-value | 0.0 |
FDR q-value | 0.27101347 |
FWER p-Value | 0.971 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | UBTF | 4210450 6840403 | 132 | 2.409 | 0.0206 | No | ||
2 | NFIL3 | 4070377 | 258 | 1.812 | 0.0347 | No | ||
3 | DDIT4 | 2570408 | 305 | 1.678 | 0.0515 | No | ||
4 | CBX3 | 1780592 3940008 | 312 | 1.671 | 0.0704 | No | ||
5 | FUS | 4760619 | 419 | 1.460 | 0.0814 | No | ||
6 | UNG | 3130110 6100364 | 573 | 1.239 | 0.0874 | No | ||
7 | RHOB | 1500309 | 632 | 1.146 | 0.0974 | No | ||
8 | CDC6 | 4570296 5360600 | 766 | 1.019 | 0.1020 | No | ||
9 | HERPUD1 | 7100440 | 1122 | 0.765 | 0.0915 | No | ||
10 | LSM2 | 510082 | 1218 | 0.704 | 0.0944 | No | ||
11 | USP10 | 2030736 2450333 | 1371 | 0.620 | 0.0933 | No | ||
12 | PMP22 | 4010239 6550072 | 1383 | 0.615 | 0.0998 | No | ||
13 | SLC20A2 | 5700577 | 1468 | 0.575 | 0.1018 | No | ||
14 | ADM | 4810121 | 1657 | 0.502 | 0.0974 | No | ||
15 | TARDBP | 870390 2350093 | 1746 | 0.472 | 0.0980 | No | ||
16 | RARS | 380390 | 1762 | 0.467 | 0.1026 | No | ||
17 | IGF2BP3 | 2810161 4230338 | 2095 | 0.370 | 0.0888 | No | ||
18 | DDX3X | 2190020 | 2105 | 0.368 | 0.0926 | No | ||
19 | BMI1 | 3830026 2630204 | 2123 | 0.361 | 0.0958 | No | ||
20 | CUL1 | 1990632 | 2173 | 0.350 | 0.0972 | No | ||
21 | PTK2 | 1780148 | 2213 | 0.339 | 0.0990 | No | ||
22 | BHLHB2 | 7040603 | 2302 | 0.317 | 0.0978 | No | ||
23 | LHFPL2 | 450020 | 2361 | 0.301 | 0.0981 | No | ||
24 | TRIP10 | 460438 | 2368 | 0.299 | 0.1013 | No | ||
25 | MPHOSPH6 | 5570164 | 2586 | 0.243 | 0.0923 | No | ||
26 | GNE | 6100465 | 2590 | 0.242 | 0.0949 | No | ||
27 | TPST1 | 2570358 | 2658 | 0.226 | 0.0938 | No | ||
28 | AURKA | 780537 | 2673 | 0.224 | 0.0957 | No | ||
29 | TWIST1 | 5130619 | 2709 | 0.215 | 0.0962 | No | ||
30 | FZD2 | 6480154 | 2791 | 0.197 | 0.0941 | No | ||
31 | PHC2 | 1430433 | 2938 | 0.174 | 0.0882 | No | ||
32 | HAS2 | 5360181 | 3193 | 0.140 | 0.0760 | No | ||
33 | ARF6 | 3520026 | 3246 | 0.134 | 0.0747 | No | ||
34 | PKP4 | 3710400 5890097 | 3367 | 0.120 | 0.0695 | No | ||
35 | ZFP36L2 | 510180 | 3517 | 0.107 | 0.0627 | No | ||
36 | PPP2R5C | 3310121 6650672 | 3703 | 0.092 | 0.0537 | No | ||
37 | PTPN1 | 2650056 | 3793 | 0.088 | 0.0499 | No | ||
38 | TOP2A | 360717 | 3931 | 0.079 | 0.0433 | No | ||
39 | CEBPD | 3360176 | 4025 | 0.075 | 0.0391 | No | ||
40 | UBE2N | 520369 2900047 | 4320 | 0.061 | 0.0238 | No | ||
41 | FZD7 | 7050706 | 4406 | 0.058 | 0.0199 | No | ||
42 | HOXB2 | 6450592 | 4477 | 0.056 | 0.0167 | No | ||
43 | SWAP70 | 2810577 2850739 5130594 | 4547 | 0.054 | 0.0136 | No | ||
44 | HDHD1A | 6220328 | 4555 | 0.053 | 0.0138 | No | ||
45 | CDK8 | 1050113 1190601 1780358 6110102 | 4646 | 0.051 | 0.0095 | No | ||
46 | CASP3 | 6620397 | 4668 | 0.050 | 0.0090 | No | ||
47 | CDYL | 4200142 4730397 6060400 | 4786 | 0.047 | 0.0031 | No | ||
48 | TUBGCP3 | 4920563 | 4813 | 0.046 | 0.0023 | No | ||
49 | NTF3 | 5890131 | 4933 | 0.043 | -0.0037 | No | ||
50 | PODXL | 130717 | 5014 | 0.041 | -0.0076 | No | ||
51 | TLE1 | 540390 1580309 3710019 | 5076 | 0.040 | -0.0105 | No | ||
52 | NR2F2 | 3170609 3310577 | 5079 | 0.040 | -0.0101 | No | ||
53 | CITED2 | 5670114 5130088 | 5161 | 0.038 | -0.0141 | No | ||
54 | FOSL2 | 870044 1230427 6520433 | 5215 | 0.037 | -0.0165 | No | ||
55 | KIF2A | 3990286 6130575 | 5329 | 0.035 | -0.0223 | No | ||
56 | CTGF | 4540577 | 5358 | 0.034 | -0.0234 | No | ||
57 | PDGFRA | 2940332 | 5734 | 0.028 | -0.0435 | No | ||
58 | BMPR1A | 2190193 4060603 | 5766 | 0.027 | -0.0449 | No | ||
59 | PPAP2B | 3190397 4730280 | 6149 | 0.022 | -0.0654 | No | ||
60 | TSPAN5 | 6770019 | 6207 | 0.021 | -0.0682 | No | ||
61 | DLX2 | 2320438 4200673 | 6255 | 0.021 | -0.0705 | No | ||
62 | BCAR3 | 1660717 | 6394 | 0.019 | -0.0778 | No | ||
63 | ARID5B | 110403 | 6432 | 0.019 | -0.0796 | No | ||
64 | CD2AP | 1940369 | 6506 | 0.019 | -0.0834 | No | ||
65 | RIPK1 | 3190025 | 6667 | 0.017 | -0.0919 | No | ||
66 | POGZ | 870348 7040286 | 6788 | 0.016 | -0.0982 | No | ||
67 | RRS1 | 4560551 | 6818 | 0.016 | -0.0996 | No | ||
68 | CDK7 | 2640451 | 6958 | 0.015 | -0.1070 | No | ||
69 | THBS1 | 4560494 430288 | 7099 | 0.014 | -0.1144 | No | ||
70 | PLEKHC1 | 2650066 | 7384 | 0.012 | -0.1297 | No | ||
71 | AGTR1 | 4780524 2680592 | 7465 | 0.012 | -0.1340 | No | ||
72 | E2F3 | 50162 460180 | 7560 | 0.011 | -0.1389 | No | ||
73 | AMD1 | 6290128 | 7794 | 0.010 | -0.1515 | No | ||
74 | EPS8 | 7050204 | 8001 | 0.009 | -0.1626 | No | ||
75 | RND3 | 940504 | 8059 | 0.009 | -0.1656 | No | ||
76 | PAFAH1B1 | 4230333 6420121 6450066 | 8128 | 0.009 | -0.1692 | No | ||
77 | POLE2 | 6110041 | 8191 | 0.008 | -0.1724 | No | ||
78 | KRIT1 | 2640500 4230435 4730184 | 8391 | 0.008 | -0.1832 | No | ||
79 | SCHIP1 | 4560152 | 8735 | 0.006 | -0.2018 | No | ||
80 | GATA2 | 6590280 | 8826 | 0.006 | -0.2066 | No | ||
81 | NCK1 | 6200575 6510050 | 8930 | 0.006 | -0.2121 | No | ||
82 | SSH1 | 7000538 | 8946 | 0.006 | -0.2129 | No | ||
83 | TIPARP | 50397 | 9033 | 0.005 | -0.2175 | No | ||
84 | SAMD4A | 1170717 | 9135 | 0.005 | -0.2229 | No | ||
85 | STRN3 | 1450093 6200685 | 9199 | 0.005 | -0.2263 | No | ||
86 | SERTAD2 | 2810673 6840450 | 9291 | 0.005 | -0.2312 | No | ||
87 | XPO1 | 540707 | 9449 | 0.004 | -0.2397 | No | ||
88 | SMAD7 | 430377 | 10452 | 0.001 | -0.2941 | No | ||
89 | SS18 | 1940440 2900072 6900129 | 10506 | 0.001 | -0.2970 | No | ||
90 | ACVR1B | 3610446 5570195 | 10584 | 0.001 | -0.3012 | No | ||
91 | HMGA2 | 2940121 3390647 5130279 6400136 | 10643 | 0.001 | -0.3043 | No | ||
92 | IDI1 | 1450736 | 10656 | 0.001 | -0.3050 | No | ||
93 | GEM | 5290082 | 10682 | 0.001 | -0.3063 | No | ||
94 | FGF5 | 5270204 | 10715 | 0.001 | -0.3080 | No | ||
95 | FHL5 | 430400 | 10851 | 0.000 | -0.3154 | No | ||
96 | STK38 | 7100114 | 10942 | -0.000 | -0.3203 | No | ||
97 | SATB2 | 2470181 | 10987 | -0.000 | -0.3227 | No | ||
98 | MFAP1 | 6660092 | 10988 | -0.000 | -0.3227 | No | ||
99 | RBM5 | 3520402 5270121 | 11228 | -0.001 | -0.3356 | No | ||
100 | SLBP | 6220601 | 11363 | -0.001 | -0.3429 | No | ||
101 | ZFAND5 | 6770673 | 11761 | -0.003 | -0.3645 | No | ||
102 | TM4SF1 | 2570021 | 11874 | -0.003 | -0.3705 | No | ||
103 | PFTK1 | 1780181 | 11956 | -0.003 | -0.3749 | No | ||
104 | CKS2 | 1410156 | 12019 | -0.004 | -0.3782 | No | ||
105 | GNAI1 | 4560390 | 12039 | -0.004 | -0.3792 | No | ||
106 | GREM1 | 3940180 | 12073 | -0.004 | -0.3810 | No | ||
107 | NUP153 | 7000452 | 12121 | -0.004 | -0.3835 | No | ||
108 | PNN | 6650504 | 12265 | -0.004 | -0.3912 | No | ||
109 | GAS1 | 2120504 | 12272 | -0.004 | -0.3915 | No | ||
110 | STXBP3 | 780706 | 12404 | -0.005 | -0.3985 | No | ||
111 | EDG2 | 6290215 | 12514 | -0.006 | -0.4044 | No | ||
112 | VEGFC | 5910494 | 12885 | -0.007 | -0.4244 | No | ||
113 | ARHGEF7 | 1690441 | 13144 | -0.009 | -0.4384 | No | ||
114 | HMGB2 | 2640603 | 13334 | -0.011 | -0.4485 | No | ||
115 | IRS1 | 1190204 | 13369 | -0.011 | -0.4502 | No | ||
116 | NRIP1 | 3190039 | 13626 | -0.014 | -0.4640 | No | ||
117 | TOPBP1 | 6020333 | 13849 | -0.016 | -0.4759 | No | ||
118 | DR1 | 5860750 | 13864 | -0.016 | -0.4764 | No | ||
119 | PUM2 | 4200441 5910446 | 13875 | -0.017 | -0.4768 | No | ||
120 | MET | 2690348 | 13895 | -0.017 | -0.4776 | No | ||
121 | YY1 | 6130451 | 14063 | -0.020 | -0.4865 | No | ||
122 | KLF9 | 3840022 | 14167 | -0.022 | -0.4918 | No | ||
123 | ZHX3 | 460615 | 14207 | -0.023 | -0.4937 | No | ||
124 | PIP5K3 | 5360112 | 14234 | -0.023 | -0.4948 | No | ||
125 | CXCL12 | 580546 4150750 4570068 | 14329 | -0.026 | -0.4997 | No | ||
126 | CCNG1 | 870402 1500685 6110594 | 14349 | -0.027 | -0.5004 | No | ||
127 | PDE4B | 4480121 | 14410 | -0.028 | -0.5033 | No | ||
128 | CYR61 | 1240408 5290026 4120452 6550008 | 14530 | -0.033 | -0.5094 | No | ||
129 | MLX | 1770450 7040452 | 14643 | -0.038 | -0.5151 | No | ||
130 | STX3 | 1190563 2640215 | 14665 | -0.039 | -0.5158 | No | ||
131 | KIF23 | 5570112 | 14673 | -0.039 | -0.5157 | No | ||
132 | SPRED2 | 510138 540195 | 14681 | -0.039 | -0.5156 | No | ||
133 | SEC24B | 460717 3060040 | 14706 | -0.041 | -0.5164 | No | ||
134 | WEE1 | 3390070 | 14710 | -0.041 | -0.5161 | No | ||
135 | PRKCD | 770592 | 14741 | -0.043 | -0.5173 | No | ||
136 | CCNA2 | 5290075 | 14835 | -0.048 | -0.5218 | No | ||
137 | STAM | 3850008 4760441 | 14899 | -0.052 | -0.5246 | No | ||
138 | ELF4 | 4850193 | 14976 | -0.056 | -0.5281 | No | ||
139 | BLCAP | 3990253 | 14992 | -0.057 | -0.5283 | No | ||
140 | BRD8 | 1170463 2900075 4050397 6590332 | 15016 | -0.058 | -0.5288 | No | ||
141 | NFE2L2 | 2810619 3390162 | 15027 | -0.059 | -0.5287 | No | ||
142 | COIL | 4480408 | 15062 | -0.062 | -0.5298 | No | ||
143 | FADD | 2360593 4210692 6520019 | 15189 | -0.071 | -0.5359 | No | ||
144 | CNOT2 | 520546 2060397 4610543 5550113 | 15191 | -0.071 | -0.5351 | No | ||
145 | MTMR3 | 1050014 4920180 | 15258 | -0.076 | -0.5378 | No | ||
146 | RAD21 | 1990278 | 15300 | -0.080 | -0.5391 | No | ||
147 | SIAH2 | 7210672 | 15325 | -0.083 | -0.5395 | No | ||
148 | RNF4 | 580286 1400152 | 15327 | -0.083 | -0.5386 | No | ||
149 | UAP1 | 3060093 | 15398 | -0.091 | -0.5414 | No | ||
150 | GBAS | 6760278 | 15443 | -0.094 | -0.5427 | No | ||
151 | GTF2E1 | 4070014 | 15463 | -0.096 | -0.5426 | No | ||
152 | EIF4E | 1580403 70133 6380215 | 15566 | -0.108 | -0.5469 | No | ||
153 | REV3L | 1090717 | 15593 | -0.111 | -0.5470 | No | ||
154 | TRIM32 | 4150332 | 15621 | -0.115 | -0.5472 | No | ||
155 | PLK4 | 430162 5720110 | 15676 | -0.120 | -0.5487 | No | ||
156 | FYN | 2100468 4760520 4850687 | 15761 | -0.130 | -0.5518 | No | ||
157 | PHTF2 | 6590053 | 15938 | -0.154 | -0.5596 | No | ||
158 | PPP1R12A | 4070066 4590162 | 16004 | -0.164 | -0.5612 | No | ||
159 | USP1 | 2760541 5690438 6220673 | 16038 | -0.169 | -0.5611 | No | ||
160 | SFRS3 | 770315 4230593 | 16062 | -0.172 | -0.5604 | No | ||
161 | CSTF3 | 3850156 5570458 | 16096 | -0.177 | -0.5601 | No | ||
162 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 16308 | -0.218 | -0.5691 | Yes | ||
163 | SNX4 | 1980358 | 16330 | -0.222 | -0.5677 | Yes | ||
164 | CASP8 | 4850154 | 16340 | -0.224 | -0.5656 | Yes | ||
165 | SMURF2 | 1940161 | 16348 | -0.226 | -0.5634 | Yes | ||
166 | TAF11 | 5720538 | 16393 | -0.235 | -0.5630 | Yes | ||
167 | NASP | 2260139 2940369 5130707 | 16526 | -0.272 | -0.5671 | Yes | ||
168 | PITPNB | 5130039 | 16569 | -0.283 | -0.5661 | Yes | ||
169 | RAB11A | 5360079 | 16595 | -0.292 | -0.5641 | Yes | ||
170 | SQLE | 50180 940092 | 16716 | -0.326 | -0.5669 | Yes | ||
171 | BACH1 | 290195 | 16764 | -0.337 | -0.5655 | Yes | ||
172 | PDCD10 | 4760500 | 16800 | -0.349 | -0.5634 | Yes | ||
173 | TBL1X | 6400524 | 16897 | -0.379 | -0.5643 | Yes | ||
174 | DICER1 | 540286 | 16911 | -0.382 | -0.5606 | Yes | ||
175 | RAF1 | 1770600 | 16929 | -0.388 | -0.5570 | Yes | ||
176 | SMAD3 | 6450671 | 16940 | -0.392 | -0.5531 | Yes | ||
177 | CENPA | 5080154 | 16958 | -0.400 | -0.5494 | Yes | ||
178 | TNFAIP8 | 2760551 | 16962 | -0.402 | -0.5449 | Yes | ||
179 | CHD1 | 4590048 | 17013 | -0.419 | -0.5428 | Yes | ||
180 | HMGCR | 2630242 | 17015 | -0.419 | -0.5381 | Yes | ||
181 | MAT2A | 4070026 4730079 6020280 | 17099 | -0.450 | -0.5374 | Yes | ||
182 | EMG1 | 50286 380242 | 17225 | -0.502 | -0.5384 | Yes | ||
183 | RAB1A | 2370671 | 17268 | -0.518 | -0.5347 | Yes | ||
184 | ITGA6 | 3830129 | 17315 | -0.539 | -0.5310 | Yes | ||
185 | DUSP1 | 6860121 | 17325 | -0.544 | -0.5252 | Yes | ||
186 | RYBP | 60746 | 17335 | -0.550 | -0.5194 | Yes | ||
187 | NCOA3 | 4540195 | 17359 | -0.562 | -0.5142 | Yes | ||
188 | THUMPD1 | 7510148 | 17368 | -0.565 | -0.5081 | Yes | ||
189 | ZBED4 | 770441 | 17386 | -0.573 | -0.5024 | Yes | ||
190 | KPNA2 | 3450114 | 17408 | -0.582 | -0.4969 | Yes | ||
191 | MAPK14 | 5290731 | 17410 | -0.583 | -0.4902 | Yes | ||
192 | ATP2A2 | 1090075 3990279 | 17491 | -0.626 | -0.4873 | Yes | ||
193 | TRIB2 | 4120605 | 17493 | -0.627 | -0.4802 | Yes | ||
194 | NFYB | 1850053 | 17508 | -0.634 | -0.4736 | Yes | ||
195 | CDR2 | 6200377 | 17515 | -0.639 | -0.4666 | Yes | ||
196 | IFNGR2 | 1500288 2100176 | 17519 | -0.640 | -0.4594 | Yes | ||
197 | FBXO46 | 870273 | 17553 | -0.659 | -0.4536 | Yes | ||
198 | UBE2G1 | 2230546 5420528 7040463 | 17589 | -0.678 | -0.4477 | Yes | ||
199 | PARP1 | 4780446 6400338 | 17601 | -0.685 | -0.4404 | Yes | ||
200 | RRAS2 | 6290170 | 17666 | -0.719 | -0.4356 | Yes | ||
201 | TLK2 | 1170161 | 17740 | -0.768 | -0.4307 | Yes | ||
202 | TLK1 | 7100605 | 17823 | -0.828 | -0.4257 | Yes | ||
203 | MAPK6 | 6760520 | 17913 | -0.909 | -0.4200 | Yes | ||
204 | SPEN | 2060041 | 17938 | -0.930 | -0.4106 | Yes | ||
205 | ATP6V1B2 | 4060528 | 18026 | -1.010 | -0.4037 | Yes | ||
206 | DYRK1A | 3190181 | 18053 | -1.036 | -0.3932 | Yes | ||
207 | DUSP11 | 1500088 4610280 | 18101 | -1.115 | -0.3829 | Yes | ||
208 | RAB14 | 6860139 | 18184 | -1.233 | -0.3732 | Yes | ||
209 | CRKL | 4050427 | 18189 | -1.245 | -0.3590 | Yes | ||
210 | MARCKS | 7040450 | 18194 | -1.252 | -0.3448 | Yes | ||
211 | SPOP | 450035 | 18217 | -1.298 | -0.3311 | Yes | ||
212 | IL4R | 2370520 | 18245 | -1.357 | -0.3169 | Yes | ||
213 | RUNX1 | 3840711 | 18253 | -1.370 | -0.3015 | Yes | ||
214 | STX7 | 5910484 | 18259 | -1.384 | -0.2859 | Yes | ||
215 | UGCG | 3420053 | 18307 | -1.492 | -0.2712 | Yes | ||
216 | STK24 | 6760484 | 18364 | -1.692 | -0.2548 | Yes | ||
217 | ARL4C | 1190279 | 18377 | -1.720 | -0.2356 | Yes | ||
218 | LBR | 4540671 | 18436 | -1.875 | -0.2172 | Yes | ||
219 | TNFAIP3 | 2900142 | 18460 | -1.987 | -0.1956 | Yes | ||
220 | BNIP2 | 1410475 6770088 | 18465 | -2.018 | -0.1725 | Yes | ||
221 | CTDSP2 | 5340315 5690133 | 18565 | -2.686 | -0.1470 | Yes | ||
222 | TLE4 | 1450064 1500519 | 18569 | -2.751 | -0.1155 | Yes | ||
223 | EMP1 | 4120438 | 18579 | -2.945 | -0.0820 | Yes | ||
224 | SRF | 70139 2320039 | 18598 | -3.207 | -0.0461 | Yes | ||
225 | TNFRSF1A | 1090390 6520735 | 18609 | -4.080 | 0.0004 | Yes |