Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | V$HOXA4_Q2 |
Enrichment Score (ES) | -0.6277224 |
Normalized Enrichment Score (NES) | -1.6614445 |
Nominal p-value | 0.0 |
FDR q-value | 0.012365819 |
FWER p-Value | 0.124 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EPHB2 | 1090288 1410377 2100541 | 237 | 1.112 | 0.0185 | No | ||
2 | PHC2 | 1430433 | 730 | 0.577 | 0.0081 | No | ||
3 | ZNF289 | 3610390 3870711 3940138 5340373 | 789 | 0.550 | 0.0204 | No | ||
4 | SLC37A4 | 6400079 | 1087 | 0.435 | 0.0166 | No | ||
5 | ADRBK1 | 1340333 | 1163 | 0.412 | 0.0241 | No | ||
6 | H2AFX | 3520082 | 1349 | 0.363 | 0.0243 | No | ||
7 | CCND1 | 460524 770309 3120576 6980398 | 1487 | 0.331 | 0.0262 | No | ||
8 | EIF5A | 1500059 5290022 6370026 | 1588 | 0.314 | 0.0296 | No | ||
9 | CAMK2D | 2370685 | 1639 | 0.305 | 0.0355 | No | ||
10 | PBXIP1 | 70131 | 1863 | 0.264 | 0.0309 | No | ||
11 | ETV6 | 610524 | 2063 | 0.234 | 0.0267 | No | ||
12 | ARHGEF2 | 3360577 | 2394 | 0.187 | 0.0141 | No | ||
13 | CAP1 | 2650278 | 2600 | 0.162 | 0.0075 | No | ||
14 | STOML2 | 1940487 | 2609 | 0.160 | 0.0116 | No | ||
15 | DNAJA2 | 2630253 6860358 | 2730 | 0.142 | 0.0091 | No | ||
16 | COMMD10 | 3120451 | 2735 | 0.141 | 0.0128 | No | ||
17 | PRKAB1 | 7050403 | 2781 | 0.136 | 0.0142 | No | ||
18 | POU2F1 | 70577 430373 4850324 5910056 | 3115 | 0.103 | -0.0010 | No | ||
19 | HIVEP3 | 3990551 | 3241 | 0.094 | -0.0051 | No | ||
20 | EOMES | 2100707 | 3365 | 0.086 | -0.0094 | No | ||
21 | CDX2 | 3850349 | 3404 | 0.084 | -0.0091 | No | ||
22 | RWDD3 | 450519 | 3492 | 0.078 | -0.0116 | No | ||
23 | TITF1 | 3390554 4540292 | 3642 | 0.070 | -0.0177 | No | ||
24 | SESN2 | 2370019 | 3669 | 0.069 | -0.0172 | No | ||
25 | OTX2 | 1190471 | 3709 | 0.067 | -0.0174 | No | ||
26 | HOXB7 | 4540706 4610358 | 3802 | 0.063 | -0.0206 | No | ||
27 | TUBB4 | 5310681 | 3925 | 0.059 | -0.0255 | No | ||
28 | TCF1 | 5390022 | 4040 | 0.055 | -0.0302 | No | ||
29 | FOXP2 | 3520561 4150372 4760524 | 4343 | 0.046 | -0.0453 | No | ||
30 | KCNJ8 | 870494 | 4530 | 0.041 | -0.0542 | No | ||
31 | SNX15 | 1240348 6770082 | 4598 | 0.040 | -0.0567 | No | ||
32 | TNNC1 | 1990575 | 4604 | 0.039 | -0.0559 | No | ||
33 | HOXC6 | 3850133 4920736 | 4742 | 0.036 | -0.0623 | No | ||
34 | HOXB8 | 3710450 | 5089 | 0.030 | -0.0802 | No | ||
35 | COL10A1 | 2360307 | 5104 | 0.030 | -0.0801 | No | ||
36 | SOX5 | 2370576 2900167 3190128 5050528 | 5174 | 0.029 | -0.0830 | No | ||
37 | CREB5 | 2320368 | 5185 | 0.028 | -0.0828 | No | ||
38 | PIM1 | 630047 | 5187 | 0.028 | -0.0820 | No | ||
39 | BLR1 | 1500300 5420017 | 5246 | 0.027 | -0.0844 | No | ||
40 | MYO18B | 7100670 | 5448 | 0.025 | -0.0946 | No | ||
41 | NR2F1 | 4120528 360402 | 5470 | 0.025 | -0.0950 | No | ||
42 | GABARAPL2 | 610204 3360047 | 5569 | 0.023 | -0.0997 | No | ||
43 | A2BP1 | 2370390 4590593 5550014 | 5581 | 0.023 | -0.0996 | No | ||
44 | ST5 | 3780204 | 5647 | 0.023 | -0.1025 | No | ||
45 | HOXC4 | 1940193 | 5896 | 0.020 | -0.1154 | No | ||
46 | ZNF219 | 5900471 | 5903 | 0.020 | -0.1152 | No | ||
47 | GPR150 | 2570440 | 5932 | 0.020 | -0.1162 | No | ||
48 | MYF5 | 1050739 | 5948 | 0.019 | -0.1164 | No | ||
49 | ROBO3 | 6550408 | 6526 | 0.015 | -0.1473 | No | ||
50 | CACNA1S | 4730465 | 6546 | 0.014 | -0.1479 | No | ||
51 | MAP3K2 | 380270 | 6621 | 0.014 | -0.1516 | No | ||
52 | PNOC | 1990114 | 6654 | 0.014 | -0.1529 | No | ||
53 | COL17A1 | 2030672 5130347 | 6661 | 0.014 | -0.1528 | No | ||
54 | HMGA2 | 2940121 3390647 5130279 6400136 | 6672 | 0.014 | -0.1530 | No | ||
55 | ZFP36L2 | 510180 | 6685 | 0.014 | -0.1533 | No | ||
56 | RFX5 | 5420128 | 6689 | 0.013 | -0.1531 | No | ||
57 | ANKRD1 | 4850685 | 6743 | 0.013 | -0.1556 | No | ||
58 | SFN | 6290301 7510608 | 6773 | 0.013 | -0.1568 | No | ||
59 | CHST9 | 4560092 | 7028 | 0.012 | -0.1702 | No | ||
60 | EMCN | 5130672 | 7045 | 0.011 | -0.1708 | No | ||
61 | GCK | 2370273 | 7318 | 0.010 | -0.1852 | No | ||
62 | ZIC1 | 670113 | 7354 | 0.010 | -0.1869 | No | ||
63 | RFX4 | 3710100 5340215 | 7401 | 0.010 | -0.1891 | No | ||
64 | PHOX2B | 5270075 | 7442 | 0.010 | -0.1910 | No | ||
65 | MYH2 | 2340433 | 7455 | 0.009 | -0.1914 | No | ||
66 | PITX2 | 870537 2690139 | 7494 | 0.009 | -0.1932 | No | ||
67 | MPP5 | 2100148 5220632 | 7520 | 0.009 | -0.1943 | No | ||
68 | LRRTM3 | 4210021 | 7601 | 0.009 | -0.1983 | No | ||
69 | HOXC5 | 1580017 | 7873 | 0.008 | -0.2128 | No | ||
70 | ITGBL1 | 6860204 | 8039 | 0.007 | -0.2216 | No | ||
71 | ELK3 | 460377 1400762 3710497 | 8163 | 0.007 | -0.2280 | No | ||
72 | FMO5 | 4810725 5390086 | 8216 | 0.007 | -0.2307 | No | ||
73 | DES | 1450341 | 8232 | 0.007 | -0.2313 | No | ||
74 | DMD | 1740041 3990332 | 8245 | 0.007 | -0.2318 | No | ||
75 | BMP4 | 380113 | 8286 | 0.007 | -0.2337 | No | ||
76 | LRRTM1 | 1690324 | 8379 | 0.006 | -0.2386 | No | ||
77 | TECTA | 2570372 | 8421 | 0.006 | -0.2406 | No | ||
78 | CHST8 | 1940050 | 8446 | 0.006 | -0.2417 | No | ||
79 | GREM1 | 3940180 | 8459 | 0.006 | -0.2422 | No | ||
80 | BBOX1 | 2030538 2370452 | 8480 | 0.006 | -0.2431 | No | ||
81 | M6PR | 2480458 3290593 3840324 | 8597 | 0.006 | -0.2493 | No | ||
82 | MYBPC2 | 1980368 | 8619 | 0.006 | -0.2502 | No | ||
83 | BDNF | 2940128 3520368 | 8662 | 0.005 | -0.2524 | No | ||
84 | PIK3R1 | 4730671 | 8693 | 0.005 | -0.2539 | No | ||
85 | NPAS2 | 770670 | 8780 | 0.005 | -0.2584 | No | ||
86 | SLC26A7 | 1850398 3830377 | 8781 | 0.005 | -0.2582 | No | ||
87 | POGZ | 870348 7040286 | 8791 | 0.005 | -0.2586 | No | ||
88 | BOC | 5270348 | 8913 | 0.005 | -0.2650 | No | ||
89 | CYBB | 3870020 | 8966 | 0.004 | -0.2677 | No | ||
90 | CGN | 5890139 6370167 6400537 | 9008 | 0.004 | -0.2698 | No | ||
91 | PRRX1 | 4120193 4480390 | 9063 | 0.004 | -0.2726 | No | ||
92 | ALK | 730008 | 9070 | 0.004 | -0.2728 | No | ||
93 | EFNB3 | 5570594 | 9117 | 0.004 | -0.2752 | No | ||
94 | LMO1 | 3170528 | 9249 | 0.004 | -0.2822 | No | ||
95 | FGF3 | 4230685 | 9287 | 0.003 | -0.2841 | No | ||
96 | GRIA1 | 1340152 3780750 4920440 | 9373 | 0.003 | -0.2887 | No | ||
97 | ASB4 | 2100064 3060059 | 9911 | 0.002 | -0.3177 | No | ||
98 | DDX5 | 940021 2630338 3440148 | 10260 | 0.001 | -0.3366 | No | ||
99 | SP7 | 1050315 | 10446 | 0.001 | -0.3466 | No | ||
100 | BMP5 | 4670048 | 10581 | 0.000 | -0.3539 | No | ||
101 | NEK7 | 4540026 | 10604 | 0.000 | -0.3551 | No | ||
102 | ARHGEF7 | 1690441 | 11217 | -0.001 | -0.3882 | No | ||
103 | ZIC4 | 1500082 | 11364 | -0.002 | -0.3961 | No | ||
104 | HOXA4 | 940152 | 11385 | -0.002 | -0.3971 | No | ||
105 | BMPR1B | 4560010 4760121 6450161 | 11430 | -0.002 | -0.3994 | No | ||
106 | CRH | 3710301 | 11433 | -0.002 | -0.3995 | No | ||
107 | HOXA9 | 610494 4730040 5130601 | 11542 | -0.002 | -0.4053 | No | ||
108 | ADAMTS17 | 6510739 | 11635 | -0.003 | -0.4102 | No | ||
109 | EDN2 | 6760647 | 11700 | -0.003 | -0.4136 | No | ||
110 | NTRK2 | 6220463 | 11740 | -0.003 | -0.4156 | No | ||
111 | AP1S2 | 780279 4280707 | 11866 | -0.003 | -0.4223 | No | ||
112 | RBMS3 | 6110722 | 11898 | -0.003 | -0.4239 | No | ||
113 | BAMBI | 6650463 | 12072 | -0.004 | -0.4332 | No | ||
114 | MITF | 380056 | 12085 | -0.004 | -0.4337 | No | ||
115 | DSG4 | 3990605 6400736 | 12238 | -0.004 | -0.4419 | No | ||
116 | FAP | 4560019 | 12255 | -0.004 | -0.4426 | No | ||
117 | MYH4 | 1940102 | 12457 | -0.005 | -0.4533 | No | ||
118 | SYNCRIP | 1690195 3140113 4670279 | 12489 | -0.005 | -0.4549 | No | ||
119 | DPP10 | 4730746 | 12524 | -0.006 | -0.4566 | No | ||
120 | MAMDC2 | 430471 | 12676 | -0.006 | -0.4646 | No | ||
121 | APEX2 | 3780044 | 12748 | -0.006 | -0.4682 | No | ||
122 | HOXD4 | 5900301 | 12777 | -0.007 | -0.4696 | No | ||
123 | MEF2C | 670025 780338 | 12780 | -0.007 | -0.4695 | No | ||
124 | NDFIP1 | 1980402 | 12963 | -0.008 | -0.4792 | No | ||
125 | ACTR3 | 1400497 | 13008 | -0.008 | -0.4813 | No | ||
126 | PAK3 | 4210136 | 13092 | -0.008 | -0.4856 | No | ||
127 | ADCYAP1 | 520086 | 13233 | -0.009 | -0.4929 | No | ||
128 | GPC3 | 6180735 | 13268 | -0.009 | -0.4945 | No | ||
129 | DSCR1L1 | 940438 | 13417 | -0.010 | -0.5023 | No | ||
130 | NUP54 | 940546 2360156 4060278 | 13537 | -0.011 | -0.5084 | No | ||
131 | CLDN14 | 5340292 | 13568 | -0.011 | -0.5097 | No | ||
132 | FBXO40 | 2190286 5670253 | 13791 | -0.013 | -0.5214 | No | ||
133 | ERG | 50154 1770739 | 13880 | -0.014 | -0.5258 | No | ||
134 | GLMN | 5290563 5890239 | 13972 | -0.016 | -0.5303 | No | ||
135 | FHOD1 | 2680279 | 14016 | -0.016 | -0.5321 | No | ||
136 | STAC2 | 7100022 | 14024 | -0.016 | -0.5321 | No | ||
137 | SHOX2 | 3190438 6450059 | 14086 | -0.017 | -0.5349 | No | ||
138 | ELMO2 | 4540685 | 14092 | -0.017 | -0.5347 | No | ||
139 | RBM4 | 2360113 5080750 | 14106 | -0.017 | -0.5349 | No | ||
140 | PPARGC1A | 4670040 | 14182 | -0.019 | -0.5384 | No | ||
141 | PCDH9 | 2100136 | 14192 | -0.019 | -0.5384 | No | ||
142 | SSH2 | 360056 | 14252 | -0.020 | -0.5410 | No | ||
143 | KLF5 | 3840348 | 14405 | -0.023 | -0.5486 | No | ||
144 | C8A | 2190601 | 14406 | -0.023 | -0.5480 | No | ||
145 | TNFSF18 | 1990458 2850520 | 14413 | -0.023 | -0.5477 | No | ||
146 | DNAJB4 | 380195 2760372 3940735 | 14423 | -0.023 | -0.5475 | No | ||
147 | SPAG9 | 580497 2510180 4210685 | 14429 | -0.023 | -0.5471 | No | ||
148 | DUSP6 | 5910286 7100070 | 14508 | -0.025 | -0.5506 | No | ||
149 | AMD1 | 6290128 | 14600 | -0.028 | -0.5548 | No | ||
150 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 14802 | -0.035 | -0.5647 | No | ||
151 | STAG2 | 4540132 | 14887 | -0.038 | -0.5682 | No | ||
152 | ZFP36L1 | 2510138 4120048 | 15003 | -0.044 | -0.5732 | No | ||
153 | STC1 | 360161 | 15685 | -0.086 | -0.6077 | No | ||
154 | ZHX1 | 2100110 2120286 | 15866 | -0.101 | -0.6146 | No | ||
155 | PER1 | 3290315 | 15912 | -0.106 | -0.6140 | No | ||
156 | NEO1 | 1990154 | 15996 | -0.116 | -0.6153 | No | ||
157 | GPX1 | 4150093 | 16023 | -0.119 | -0.6133 | No | ||
158 | CS | 5080600 | 16092 | -0.125 | -0.6135 | No | ||
159 | CDC14A | 4050132 | 16158 | -0.133 | -0.6133 | No | ||
160 | THRA | 6770341 110164 1990600 | 16193 | -0.138 | -0.6112 | No | ||
161 | MBNL2 | 3450707 | 16344 | -0.161 | -0.6148 | No | ||
162 | NSD1 | 4560519 4780672 | 16524 | -0.193 | -0.6191 | No | ||
163 | FLI1 | 3990142 | 16684 | -0.225 | -0.6214 | Yes | ||
164 | CACNB3 | 2480035 4540184 | 16743 | -0.239 | -0.6178 | Yes | ||
165 | MMP12 | 4920070 | 16772 | -0.247 | -0.6123 | Yes | ||
166 | DICER1 | 540286 | 16808 | -0.255 | -0.6070 | Yes | ||
167 | DLX1 | 360168 | 16912 | -0.279 | -0.6048 | Yes | ||
168 | APOE | 4200671 | 16950 | -0.289 | -0.5986 | Yes | ||
169 | NXF1 | 1570377 | 17319 | -0.391 | -0.6076 | Yes | ||
170 | RPP25 | 6620048 | 17402 | -0.420 | -0.6002 | Yes | ||
171 | THRAP4 | 3170041 5050347 | 17515 | -0.459 | -0.5933 | Yes | ||
172 | TOB1 | 4150138 | 17941 | -0.646 | -0.5981 | Yes | ||
173 | RPA3 | 5700136 | 17986 | -0.672 | -0.5816 | Yes | ||
174 | CYLD | 6590079 | 18171 | -0.808 | -0.5688 | Yes | ||
175 | SAV1 | 5420541 | 18335 | -0.985 | -0.5499 | Yes | ||
176 | CNN3 | 6110020 | 18519 | -1.472 | -0.5183 | Yes | ||
177 | EIF4G2 | 3800575 6860184 | 18522 | -1.497 | -0.4762 | Yes | ||
178 | SMOC1 | 840039 | 18549 | -1.657 | -0.4309 | Yes | ||
179 | PTPN22 | 1690647 7100239 | 18606 | -2.981 | -0.3499 | Yes | ||
180 | MMP14 | 670079 | 18610 | -3.170 | -0.2608 | Yes | ||
181 | ATP2A3 | 130440 2190451 | 18612 | -3.349 | -0.1664 | Yes | ||
182 | ARID1A | 2630022 1690551 4810110 | 18616 | -5.910 | -0.0000 | Yes |