Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q6 |
Enrichment Score (ES) | 0.51010936 |
Normalized Enrichment Score (NES) | 1.3028064 |
Nominal p-value | 0.031539887 |
FDR q-value | 0.91164404 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NCDN | 50040 1980739 3520603 | 104 | 1.679 | 0.0388 | Yes | ||
2 | TGFBR2 | 1780711 1980537 6550398 | 117 | 1.576 | 0.0798 | Yes | ||
3 | ENO1 | 5340128 | 122 | 1.566 | 0.1210 | Yes | ||
4 | UBQLN1 | 110280 730376 2470133 6590594 | 123 | 1.561 | 0.1623 | Yes | ||
5 | ETV5 | 110017 | 145 | 1.443 | 0.1993 | Yes | ||
6 | ECM1 | 940068 5390309 | 194 | 1.229 | 0.2292 | Yes | ||
7 | NDRG2 | 450403 | 256 | 1.078 | 0.2544 | Yes | ||
8 | PADI4 | 1740075 4810441 | 274 | 1.042 | 0.2810 | Yes | ||
9 | MAPK3 | 580161 4780035 | 307 | 0.971 | 0.3050 | Yes | ||
10 | ALDOA | 6290672 | 312 | 0.964 | 0.3303 | Yes | ||
11 | ABCD1 | 5670373 | 618 | 0.640 | 0.3306 | Yes | ||
12 | PKP3 | 3710048 | 621 | 0.636 | 0.3473 | Yes | ||
13 | SYTL1 | 510487 | 726 | 0.579 | 0.3570 | Yes | ||
14 | CAMKK1 | 6370324 | 790 | 0.549 | 0.3681 | Yes | ||
15 | ITPKC | 5420021 | 791 | 0.549 | 0.3826 | Yes | ||
16 | AKT1S1 | 1660048 | 821 | 0.530 | 0.3951 | Yes | ||
17 | VAMP5 | 3830300 | 854 | 0.515 | 0.4070 | Yes | ||
18 | RTN4 | 50725 630647 870097 870184 | 861 | 0.511 | 0.4202 | Yes | ||
19 | ABCA2 | 5050039 | 929 | 0.486 | 0.4294 | Yes | ||
20 | TBC1D17 | 1780450 | 937 | 0.484 | 0.4418 | Yes | ||
21 | DCTN2 | 540471 3780717 | 1019 | 0.457 | 0.4495 | Yes | ||
22 | CAPNS1 | 3940113 | 1158 | 0.413 | 0.4529 | Yes | ||
23 | LMNA | 520471 1500075 3190167 4210020 | 1293 | 0.375 | 0.4556 | Yes | ||
24 | ADCK4 | 1660180 | 1318 | 0.370 | 0.4641 | Yes | ||
25 | PDGFRB | 6450279 | 1374 | 0.356 | 0.4705 | Yes | ||
26 | RAB3D | 4210253 | 1423 | 0.348 | 0.4771 | Yes | ||
27 | HDAC3 | 4060072 | 1470 | 0.336 | 0.4835 | Yes | ||
28 | ABHD4 | 6760450 | 1509 | 0.327 | 0.4901 | Yes | ||
29 | TAGLN2 | 4560121 | 1568 | 0.318 | 0.4953 | Yes | ||
30 | UBE2C | 6130017 | 1656 | 0.302 | 0.4986 | Yes | ||
31 | ROM1 | 3130685 | 1671 | 0.299 | 0.5058 | Yes | ||
32 | ABHD2 | 4850504 6840010 | 1732 | 0.287 | 0.5101 | Yes | ||
33 | RIT1 | 5390338 | 2028 | 0.240 | 0.5004 | No | ||
34 | AP2A2 | 130082 | 2128 | 0.225 | 0.5010 | No | ||
35 | TMEM24 | 5860039 | 2200 | 0.217 | 0.5029 | No | ||
36 | VASP | 7050500 | 2292 | 0.202 | 0.5033 | No | ||
37 | HSPB8 | 540563 | 2377 | 0.190 | 0.5038 | No | ||
38 | VIM | 20431 | 2461 | 0.179 | 0.5040 | No | ||
39 | PSMD2 | 4670706 5050364 | 2506 | 0.172 | 0.5062 | No | ||
40 | SCRN1 | 6040025 6580019 | 2577 | 0.164 | 0.5067 | No | ||
41 | BAZ2A | 730184 | 2653 | 0.153 | 0.5067 | No | ||
42 | FHL3 | 1090369 2650017 | 2719 | 0.143 | 0.5070 | No | ||
43 | NFRKB | 3130538 | 3245 | 0.094 | 0.4810 | No | ||
44 | ADORA2A | 1990687 | 3284 | 0.090 | 0.4813 | No | ||
45 | BLMH | 1410438 | 3399 | 0.084 | 0.4773 | No | ||
46 | MDFI | 6200041 | 3448 | 0.081 | 0.4768 | No | ||
47 | DCN | 510332 5340026 5900711 6550092 | 3523 | 0.077 | 0.4749 | No | ||
48 | EPHA2 | 5890056 | 3888 | 0.060 | 0.4567 | No | ||
49 | CLSTN3 | 2350685 | 3922 | 0.059 | 0.4565 | No | ||
50 | ELA1 | 3390167 | 4052 | 0.055 | 0.4509 | No | ||
51 | PAPPA | 4230463 | 4079 | 0.054 | 0.4509 | No | ||
52 | AXIN2 | 3850131 | 4141 | 0.052 | 0.4490 | No | ||
53 | GADD45A | 2900717 | 4152 | 0.051 | 0.4498 | No | ||
54 | RB1CC1 | 510494 7100072 | 4412 | 0.044 | 0.4369 | No | ||
55 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 4440 | 0.044 | 0.4366 | No | ||
56 | NRIP3 | 1340372 | 4784 | 0.036 | 0.4189 | No | ||
57 | HSPB7 | 1190441 | 4960 | 0.033 | 0.4103 | No | ||
58 | STAT5B | 6200026 | 5048 | 0.031 | 0.4064 | No | ||
59 | FLNC | 2360048 5050270 | 5396 | 0.025 | 0.3882 | No | ||
60 | DIRAS1 | 2640270 | 5664 | 0.022 | 0.3743 | No | ||
61 | COBL | 2480452 6110066 | 5735 | 0.022 | 0.3711 | No | ||
62 | GGN | 1410528 4210082 5290170 | 5777 | 0.021 | 0.3695 | No | ||
63 | EEF1A2 | 2260162 5290086 | 5908 | 0.020 | 0.3629 | No | ||
64 | PSME4 | 380348 1770131 | 6001 | 0.019 | 0.3584 | No | ||
65 | PVALB | 5570450 | 6012 | 0.019 | 0.3584 | No | ||
66 | STX17 | 2260037 | 6053 | 0.018 | 0.3567 | No | ||
67 | ST18 | 5720537 | 6085 | 0.018 | 0.3555 | No | ||
68 | MMP9 | 580338 | 6167 | 0.017 | 0.3516 | No | ||
69 | MAP1A | 4920576 | 6232 | 0.017 | 0.3485 | No | ||
70 | BMP2 | 6620687 | 6399 | 0.015 | 0.3399 | No | ||
71 | MMP7 | 1780497 | 6729 | 0.013 | 0.3224 | No | ||
72 | RIMS1 | 5670022 | 6753 | 0.013 | 0.3215 | No | ||
73 | SFN | 6290301 7510608 | 6773 | 0.013 | 0.3209 | No | ||
74 | PTPRH | 3870070 | 6886 | 0.012 | 0.3151 | No | ||
75 | IL23A | 6290044 | 6894 | 0.012 | 0.3150 | No | ||
76 | TLL1 | 2680315 | 6940 | 0.012 | 0.3129 | No | ||
77 | GPR3 | 2970452 | 7029 | 0.012 | 0.3085 | No | ||
78 | AK5 | 6290348 | 7039 | 0.011 | 0.3083 | No | ||
79 | OLR1 | 50025 3840484 | 7164 | 0.011 | 0.3018 | No | ||
80 | FGF12 | 1740446 2360037 | 7453 | 0.009 | 0.2865 | No | ||
81 | DHRS3 | 360609 | 7478 | 0.009 | 0.2854 | No | ||
82 | SCEL | 3190129 | 7660 | 0.009 | 0.2758 | No | ||
83 | TRIB1 | 2320435 | 7666 | 0.009 | 0.2758 | No | ||
84 | EIF3S1 | 6130368 6770044 | 7811 | 0.008 | 0.2682 | No | ||
85 | ELK3 | 460377 1400762 3710497 | 8163 | 0.007 | 0.2493 | No | ||
86 | KBTBD5 | 6350025 | 8335 | 0.006 | 0.2402 | No | ||
87 | NR0B2 | 2470692 | 8373 | 0.006 | 0.2384 | No | ||
88 | SPATS2 | 2360066 | 8562 | 0.006 | 0.2283 | No | ||
89 | TIAL1 | 4150048 6510605 | 8678 | 0.005 | 0.2222 | No | ||
90 | GFAP | 2060092 | 8700 | 0.005 | 0.2212 | No | ||
91 | LPP | 1660541 | 8740 | 0.005 | 0.2192 | No | ||
92 | WDFY3 | 3610041 4560333 4570273 | 8760 | 0.005 | 0.2183 | No | ||
93 | GAB2 | 1410280 2340520 4280040 | 8814 | 0.005 | 0.2156 | No | ||
94 | GJB3 | 2650040 | 8941 | 0.004 | 0.2089 | No | ||
95 | PRDM1 | 3170347 3520301 | 8961 | 0.004 | 0.2080 | No | ||
96 | P2RXL1 | 4730390 5220446 | 9148 | 0.004 | 0.1980 | No | ||
97 | IGSF9 | 1770411 | 9176 | 0.004 | 0.1966 | No | ||
98 | PSMD11 | 2340538 6510053 | 9178 | 0.004 | 0.1967 | No | ||
99 | MYBPH | 2190711 | 9354 | 0.003 | 0.1873 | No | ||
100 | SFTPC | 3290133 | 9410 | 0.003 | 0.1844 | No | ||
101 | C3AR1 | 5720131 | 9561 | 0.003 | 0.1763 | No | ||
102 | ANXA7 | 6110446 | 9599 | 0.003 | 0.1744 | No | ||
103 | S100A5 | 4120592 | 9761 | 0.002 | 0.1657 | No | ||
104 | FBXW11 | 6450632 | 9783 | 0.002 | 0.1646 | No | ||
105 | SYT2 | 60609 | 9848 | 0.002 | 0.1612 | No | ||
106 | UCHL3 | 1240735 | 9926 | 0.002 | 0.1571 | No | ||
107 | HOXA11 | 6980133 | 10256 | 0.001 | 0.1392 | No | ||
108 | CRYBA2 | 5900138 | 10452 | 0.000 | 0.1287 | No | ||
109 | SHC3 | 2690398 | 10481 | 0.000 | 0.1272 | No | ||
110 | AP2B1 | 1450184 2370148 3520139 4850593 | 10505 | 0.000 | 0.1259 | No | ||
111 | IL1RN | 2370333 | 10595 | 0.000 | 0.1211 | No | ||
112 | PHLDA2 | 4810494 | 10607 | 0.000 | 0.1205 | No | ||
113 | TRPV3 | 540341 | 10955 | -0.001 | 0.1017 | No | ||
114 | EFNA1 | 3840672 | 11079 | -0.001 | 0.0951 | No | ||
115 | DSTN | 3140592 | 11141 | -0.001 | 0.0918 | No | ||
116 | IL9 | 3440338 | 11162 | -0.001 | 0.0907 | No | ||
117 | USP13 | 1450670 | 11792 | -0.003 | 0.0567 | No | ||
118 | SLC35E4 | 2370711 | 11804 | -0.003 | 0.0562 | No | ||
119 | UCN2 | 4590372 | 11910 | -0.003 | 0.0506 | No | ||
120 | OMG | 6760066 | 11937 | -0.003 | 0.0492 | No | ||
121 | FAP | 4560019 | 12255 | -0.004 | 0.0322 | No | ||
122 | HOXD3 | 6450154 | 12260 | -0.005 | 0.0321 | No | ||
123 | PLCD1 | 2030484 | 12779 | -0.007 | 0.0041 | No | ||
124 | PTPRN | 5900577 | 12877 | -0.007 | -0.0009 | No | ||
125 | XLKD1 | 520441 | 13040 | -0.008 | -0.0095 | No | ||
126 | SNCB | 3360133 | 13175 | -0.009 | -0.0166 | No | ||
127 | SPARC | 1690086 | 13248 | -0.009 | -0.0202 | No | ||
128 | GNAI1 | 4560390 | 13372 | -0.010 | -0.0266 | No | ||
129 | DSCR1L1 | 940438 | 13417 | -0.010 | -0.0288 | No | ||
130 | SLC26A1 | 2190142 | 13555 | -0.011 | -0.0359 | No | ||
131 | PFTK1 | 1780181 | 13736 | -0.013 | -0.0453 | No | ||
132 | LAMC2 | 450692 2680041 4200059 4670148 | 13945 | -0.015 | -0.0562 | No | ||
133 | KCNA2 | 5080403 | 13982 | -0.016 | -0.0577 | No | ||
134 | MARK1 | 450484 | 14010 | -0.016 | -0.0588 | No | ||
135 | NFATC4 | 2470735 | 14015 | -0.016 | -0.0586 | No | ||
136 | PCDH9 | 2100136 | 14192 | -0.019 | -0.0676 | No | ||
137 | PTP4A1 | 130692 | 14223 | -0.019 | -0.0687 | No | ||
138 | IBRDC2 | 5130041 | 14395 | -0.023 | -0.0774 | No | ||
139 | IDS | 360619 5720161 | 14410 | -0.023 | -0.0776 | No | ||
140 | LAPTM5 | 5550372 | 14519 | -0.026 | -0.0827 | No | ||
141 | DTNA | 1340600 1780731 2340278 2850132 | 14529 | -0.026 | -0.0826 | No | ||
142 | LAMA3 | 1190131 5290239 | 14576 | -0.027 | -0.0843 | No | ||
143 | NEK6 | 3360687 | 14712 | -0.032 | -0.0908 | No | ||
144 | PITPNC1 | 3990017 | 14771 | -0.034 | -0.0931 | No | ||
145 | APBA2BP | 5700341 | 14904 | -0.039 | -0.0992 | No | ||
146 | EIF4E | 1580403 70133 6380215 | 14918 | -0.039 | -0.0989 | No | ||
147 | CASK | 2340215 3290576 6770215 | 14939 | -0.041 | -0.0989 | No | ||
148 | ROCK2 | 1780035 5720025 | 15017 | -0.044 | -0.1019 | No | ||
149 | PEA15 | 4590685 | 15161 | -0.052 | -0.1083 | No | ||
150 | VDR | 130156 510438 | 15169 | -0.052 | -0.1073 | No | ||
151 | LTBP3 | 1190162 2650440 6520451 | 15196 | -0.053 | -0.1073 | No | ||
152 | COL27A1 | 1740390 | 15200 | -0.053 | -0.1060 | No | ||
153 | LRRFIP2 | 670575 730152 6590438 | 15205 | -0.054 | -0.1048 | No | ||
154 | MCART1 | 5270059 | 15304 | -0.060 | -0.1086 | No | ||
155 | SCOC | 610048 2230053 | 15370 | -0.064 | -0.1104 | No | ||
156 | PSMD4 | 430068 | 15520 | -0.073 | -0.1165 | No | ||
157 | RIN1 | 510593 | 15581 | -0.078 | -0.1177 | No | ||
158 | GPX1 | 4150093 | 16023 | -0.119 | -0.1385 | No | ||
159 | APOBEC1 | 4610022 | 16038 | -0.121 | -0.1361 | No | ||
160 | GTF2B | 6860685 | 16063 | -0.122 | -0.1341 | No | ||
161 | CMAS | 2190129 | 16073 | -0.123 | -0.1314 | No | ||
162 | POLR3E | 380152 | 16146 | -0.131 | -0.1318 | No | ||
163 | TRAF3 | 5690647 | 16236 | -0.145 | -0.1328 | No | ||
164 | ABI3 | 1740563 | 16250 | -0.146 | -0.1296 | No | ||
165 | LAMC1 | 4730025 | 16293 | -0.153 | -0.1279 | No | ||
166 | BTK | 3130044 | 16356 | -0.162 | -0.1270 | No | ||
167 | CDKN1A | 4050088 6400706 | 16374 | -0.164 | -0.1235 | No | ||
168 | YWHAZ | 1230717 | 16534 | -0.195 | -0.1270 | No | ||
169 | SLC16A6 | 1690156 | 16569 | -0.200 | -0.1236 | No | ||
170 | PSMD12 | 730044 | 16823 | -0.259 | -0.1304 | No | ||
171 | RBBP7 | 430113 450450 2370309 | 17096 | -0.331 | -0.1364 | No | ||
172 | NEFH | 630239 | 17100 | -0.332 | -0.1278 | No | ||
173 | WNT6 | 4570364 | 17177 | -0.350 | -0.1227 | No | ||
174 | CYFIP1 | 5690082 | 17246 | -0.370 | -0.1166 | No | ||
175 | PKN3 | 2260538 | 17352 | -0.403 | -0.1116 | No | ||
176 | ICK | 1580746 3140021 | 17495 | -0.454 | -0.1073 | No | ||
177 | PSMD7 | 2030619 6220594 | 17660 | -0.515 | -0.1026 | No | ||
178 | TRIM8 | 6130441 | 17683 | -0.528 | -0.0898 | No | ||
179 | XPOT | 7050184 | 17807 | -0.578 | -0.0812 | No | ||
180 | PDAP1 | 1410735 | 18081 | -0.739 | -0.0765 | No | ||
181 | ATP1B1 | 3130594 | 18082 | -0.740 | -0.0569 | No | ||
182 | PPP2CA | 3990113 | 18202 | -0.833 | -0.0413 | No | ||
183 | NR1D1 | 2360471 770746 6590204 | 18363 | -1.024 | -0.0229 | No | ||
184 | TCF12 | 3610324 7000156 | 18494 | -1.384 | 0.0066 | No |