Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | truncNotch |
GeneSet | V$AP1FJ_Q2 |
Enrichment Score (ES) | 0.4903617 |
Normalized Enrichment Score (NES) | 1.2705005 |
Nominal p-value | 0.041516244 |
FDR q-value | 0.9359328 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CIZ1 | 4150128 6130484 | 38 | 2.567 | 0.0716 | Yes | ||
2 | NCDN | 50040 1980739 3520603 | 104 | 1.679 | 0.1162 | Yes | ||
3 | TGFBR2 | 1780711 1980537 6550398 | 117 | 1.576 | 0.1607 | Yes | ||
4 | UBQLN1 | 110280 730376 2470133 6590594 | 123 | 1.561 | 0.2052 | Yes | ||
5 | ETV5 | 110017 | 145 | 1.443 | 0.2454 | Yes | ||
6 | RPL23 | 2260452 4850435 6450673 | 260 | 1.057 | 0.2696 | Yes | ||
7 | MAPK3 | 580161 4780035 | 307 | 0.971 | 0.2949 | Yes | ||
8 | GNGT2 | 540176 | 423 | 0.830 | 0.3125 | Yes | ||
9 | RAB37 | 1980725 | 432 | 0.820 | 0.3356 | Yes | ||
10 | SYTL1 | 510487 | 726 | 0.579 | 0.3363 | Yes | ||
11 | CAMKK1 | 6370324 | 790 | 0.549 | 0.3486 | Yes | ||
12 | DTX2 | 4210041 7000008 | 815 | 0.534 | 0.3626 | Yes | ||
13 | AKT1S1 | 1660048 | 821 | 0.530 | 0.3775 | Yes | ||
14 | EEF1A1 | 1980193 1990195 4670735 | 857 | 0.513 | 0.3904 | Yes | ||
15 | RTN4 | 50725 630647 870097 870184 | 861 | 0.511 | 0.4049 | Yes | ||
16 | TBC1D17 | 1780450 | 937 | 0.484 | 0.4147 | Yes | ||
17 | CAPNS1 | 3940113 | 1158 | 0.413 | 0.4146 | Yes | ||
18 | PPP1R9B | 3130619 | 1200 | 0.400 | 0.4238 | Yes | ||
19 | LMNA | 520471 1500075 3190167 4210020 | 1293 | 0.375 | 0.4296 | Yes | ||
20 | KCNN4 | 2680129 | 1306 | 0.373 | 0.4396 | Yes | ||
21 | PDGFRB | 6450279 | 1374 | 0.356 | 0.4462 | Yes | ||
22 | PRKACA | 2640731 4050048 | 1442 | 0.342 | 0.4524 | Yes | ||
23 | HDAC3 | 4060072 | 1470 | 0.336 | 0.4606 | Yes | ||
24 | AGPAT1 | 610056 | 1562 | 0.319 | 0.4648 | Yes | ||
25 | TAGLN2 | 4560121 | 1568 | 0.318 | 0.4736 | Yes | ||
26 | UBE2C | 6130017 | 1656 | 0.302 | 0.4776 | Yes | ||
27 | ROM1 | 3130685 | 1671 | 0.299 | 0.4854 | Yes | ||
28 | FIGF | 7040673 | 1846 | 0.268 | 0.4836 | Yes | ||
29 | ARRDC4 | 2810019 | 1926 | 0.254 | 0.4866 | Yes | ||
30 | RNF5 | 2760088 | 2066 | 0.234 | 0.4858 | Yes | ||
31 | TRIP10 | 460438 | 2341 | 0.194 | 0.4765 | Yes | ||
32 | FKBP8 | 4060019 | 2349 | 0.194 | 0.4817 | Yes | ||
33 | VIM | 20431 | 2461 | 0.179 | 0.4808 | Yes | ||
34 | SCRN1 | 6040025 6580019 | 2577 | 0.164 | 0.4793 | Yes | ||
35 | ISG20 | 1770750 | 2590 | 0.163 | 0.4833 | Yes | ||
36 | STOML2 | 1940487 | 2609 | 0.160 | 0.4869 | Yes | ||
37 | BAZ2A | 730184 | 2653 | 0.153 | 0.4889 | Yes | ||
38 | FHL3 | 1090369 2650017 | 2719 | 0.143 | 0.4895 | Yes | ||
39 | IGFBP6 | 1580181 | 2776 | 0.136 | 0.4904 | Yes | ||
40 | SLC6A9 | 2470520 | 2887 | 0.126 | 0.4880 | No | ||
41 | MMP19 | 5080377 | 3077 | 0.107 | 0.4808 | No | ||
42 | FARP1 | 5290102 7100341 | 3112 | 0.103 | 0.4819 | No | ||
43 | RGS6 | 6040601 | 3232 | 0.094 | 0.4782 | No | ||
44 | BLMH | 1410438 | 3399 | 0.084 | 0.4716 | No | ||
45 | MDFI | 6200041 | 3448 | 0.081 | 0.4713 | No | ||
46 | GABBR1 | 2850519 2850735 | 3500 | 0.078 | 0.4707 | No | ||
47 | DCN | 510332 5340026 5900711 6550092 | 3523 | 0.077 | 0.4717 | No | ||
48 | DUSP13 | 6400152 | 3557 | 0.075 | 0.4721 | No | ||
49 | SLC38A3 | 5340142 | 3846 | 0.061 | 0.4582 | No | ||
50 | BLVRB | 7040707 | 3863 | 0.061 | 0.4591 | No | ||
51 | EPHA2 | 5890056 | 3888 | 0.060 | 0.4595 | No | ||
52 | CLSTN3 | 2350685 | 3922 | 0.059 | 0.4594 | No | ||
53 | PTPRR | 130121 3990273 | 4063 | 0.054 | 0.4534 | No | ||
54 | PAPPA | 4230463 | 4079 | 0.054 | 0.4541 | No | ||
55 | AXIN2 | 3850131 | 4141 | 0.052 | 0.4523 | No | ||
56 | CMYA5 | 770528 6860075 | 4173 | 0.051 | 0.4520 | No | ||
57 | CORO1C | 4570397 | 4571 | 0.040 | 0.4317 | No | ||
58 | IRAK1 | 4120593 | 4692 | 0.037 | 0.4262 | No | ||
59 | NRIP3 | 1340372 | 4784 | 0.036 | 0.4223 | No | ||
60 | FOS | 1850315 | 4806 | 0.035 | 0.4222 | No | ||
61 | PAFAH1B1 | 4230333 6420121 6450066 | 5017 | 0.032 | 0.4117 | No | ||
62 | STAT5B | 6200026 | 5048 | 0.031 | 0.4110 | No | ||
63 | GSN | 3830168 | 5321 | 0.026 | 0.3970 | No | ||
64 | FLNC | 2360048 5050270 | 5396 | 0.025 | 0.3937 | No | ||
65 | HS3ST3B1 | 380040 | 5417 | 0.025 | 0.3933 | No | ||
66 | GGN | 1410528 4210082 5290170 | 5777 | 0.021 | 0.3744 | No | ||
67 | GIF | 2260056 | 5827 | 0.021 | 0.3724 | No | ||
68 | EEF1A2 | 2260162 5290086 | 5908 | 0.020 | 0.3686 | No | ||
69 | GPR150 | 2570440 | 5932 | 0.020 | 0.3679 | No | ||
70 | STX17 | 2260037 | 6053 | 0.018 | 0.3619 | No | ||
71 | ST18 | 5720537 | 6085 | 0.018 | 0.3607 | No | ||
72 | MAP1A | 4920576 | 6232 | 0.017 | 0.3533 | No | ||
73 | SGTB | 460170 | 6500 | 0.015 | 0.3392 | No | ||
74 | LRP1B | 1450193 | 6605 | 0.014 | 0.3340 | No | ||
75 | MMP7 | 1780497 | 6729 | 0.013 | 0.3277 | No | ||
76 | HOXD9 | 2570181 | 6739 | 0.013 | 0.3276 | No | ||
77 | PTPRH | 3870070 | 6886 | 0.012 | 0.3200 | No | ||
78 | IL23A | 6290044 | 6894 | 0.012 | 0.3200 | No | ||
79 | AK5 | 6290348 | 7039 | 0.011 | 0.3125 | No | ||
80 | JMJD1C | 940575 2120025 | 7044 | 0.011 | 0.3126 | No | ||
81 | DNM1 | 1660097 5340519 | 7108 | 0.011 | 0.3095 | No | ||
82 | PORCN | 5050519 | 7182 | 0.011 | 0.3059 | No | ||
83 | DNAJB5 | 2900215 | 7268 | 0.010 | 0.3016 | No | ||
84 | SV2A | 1450039 5570685 | 7333 | 0.010 | 0.2984 | No | ||
85 | FGF12 | 1740446 2360037 | 7453 | 0.009 | 0.2922 | No | ||
86 | NPY | 3170138 | 7496 | 0.009 | 0.2902 | No | ||
87 | EIF3S1 | 6130368 6770044 | 7811 | 0.008 | 0.2734 | No | ||
88 | FGF11 | 840292 | 8019 | 0.007 | 0.2624 | No | ||
89 | SIX4 | 6760022 | 8040 | 0.007 | 0.2615 | No | ||
90 | GABRA1 | 130372 | 8190 | 0.007 | 0.2536 | No | ||
91 | KBTBD5 | 6350025 | 8335 | 0.006 | 0.2460 | No | ||
92 | TIAL1 | 4150048 6510605 | 8678 | 0.005 | 0.2276 | No | ||
93 | LPP | 1660541 | 8740 | 0.005 | 0.2244 | No | ||
94 | GAB2 | 1410280 2340520 4280040 | 8814 | 0.005 | 0.2206 | No | ||
95 | CRYGS | 2680398 | 8936 | 0.005 | 0.2141 | No | ||
96 | GJB3 | 2650040 | 8941 | 0.004 | 0.2140 | No | ||
97 | PRDM1 | 3170347 3520301 | 8961 | 0.004 | 0.2131 | No | ||
98 | PSMD11 | 2340538 6510053 | 9178 | 0.004 | 0.2015 | No | ||
99 | MYBPH | 2190711 | 9354 | 0.003 | 0.1921 | No | ||
100 | PSMA3 | 5900047 7040161 | 9539 | 0.003 | 0.1822 | No | ||
101 | SDCBP | 460487 2190039 5270441 | 9580 | 0.003 | 0.1801 | No | ||
102 | ANXA7 | 6110446 | 9599 | 0.003 | 0.1792 | No | ||
103 | SPTBN4 | 4150279 5270286 | 9733 | 0.002 | 0.1721 | No | ||
104 | S100A5 | 4120592 | 9761 | 0.002 | 0.1707 | No | ||
105 | FBXW11 | 6450632 | 9783 | 0.002 | 0.1696 | No | ||
106 | HOXA11 | 6980133 | 10256 | 0.001 | 0.1440 | No | ||
107 | PLAC1 | 2350594 | 10294 | 0.001 | 0.1420 | No | ||
108 | CRYBA2 | 5900138 | 10452 | 0.000 | 0.1335 | No | ||
109 | SHC3 | 2690398 | 10481 | 0.000 | 0.1320 | No | ||
110 | IL1RN | 2370333 | 10595 | 0.000 | 0.1259 | No | ||
111 | MAPRE3 | 7050504 | 10649 | 0.000 | 0.1230 | No | ||
112 | CYP24A1 | 2340338 | 10669 | 0.000 | 0.1220 | No | ||
113 | SRC | 580132 | 10877 | -0.001 | 0.1108 | No | ||
114 | CRK | 1230162 4780128 | 10920 | -0.001 | 0.1085 | No | ||
115 | GRIN2D | 6620372 | 10949 | -0.001 | 0.1070 | No | ||
116 | TRPV3 | 540341 | 10955 | -0.001 | 0.1068 | No | ||
117 | EFNA1 | 3840672 | 11079 | -0.001 | 0.1001 | No | ||
118 | KLHL1 | 6350021 | 11103 | -0.001 | 0.0989 | No | ||
119 | DSTN | 3140592 | 11141 | -0.001 | 0.0969 | No | ||
120 | PAX9 | 3850519 | 11157 | -0.001 | 0.0962 | No | ||
121 | IL9 | 3440338 | 11162 | -0.001 | 0.0960 | No | ||
122 | TLE4 | 1450064 1500519 | 11289 | -0.002 | 0.0892 | No | ||
123 | ATOH8 | 4540204 | 11397 | -0.002 | 0.0834 | No | ||
124 | NTRK2 | 6220463 | 11740 | -0.003 | 0.0649 | No | ||
125 | USP13 | 1450670 | 11792 | -0.003 | 0.0623 | No | ||
126 | SLC35E4 | 2370711 | 11804 | -0.003 | 0.0618 | No | ||
127 | UCN2 | 4590372 | 11910 | -0.003 | 0.0562 | No | ||
128 | OMG | 6760066 | 11937 | -0.003 | 0.0548 | No | ||
129 | TSNAXIP1 | 1770270 6180577 | 12050 | -0.004 | 0.0489 | No | ||
130 | PLCD1 | 2030484 | 12779 | -0.007 | 0.0096 | No | ||
131 | GOLGA4 | 460300 | 12785 | -0.007 | 0.0095 | No | ||
132 | LAMB3 | 7100301 | 12817 | -0.007 | 0.0080 | No | ||
133 | FLRT1 | 4540348 | 12824 | -0.007 | 0.0079 | No | ||
134 | PTPRN | 5900577 | 12877 | -0.007 | 0.0052 | No | ||
135 | XLKD1 | 520441 | 13040 | -0.008 | -0.0033 | No | ||
136 | AKAP1 | 110148 1740735 2260019 7000563 | 13050 | -0.008 | -0.0036 | No | ||
137 | SNCB | 3360133 | 13175 | -0.009 | -0.0101 | No | ||
138 | RAD23B | 2190671 | 13365 | -0.010 | -0.0200 | No | ||
139 | GNAI1 | 4560390 | 13372 | -0.010 | -0.0201 | No | ||
140 | ZNF23 | 1090537 | 13446 | -0.010 | -0.0238 | No | ||
141 | IL6 | 380133 | 13641 | -0.012 | -0.0339 | No | ||
142 | UBE3A | 1240152 2690438 5860609 | 13717 | -0.013 | -0.0377 | No | ||
143 | CYP11A1 | 3450037 | 13744 | -0.013 | -0.0387 | No | ||
144 | CMYA1 | 6900632 | 13855 | -0.014 | -0.0443 | No | ||
145 | AKT3 | 1580270 3290278 | 13941 | -0.015 | -0.0484 | No | ||
146 | LAMC2 | 450692 2680041 4200059 4670148 | 13945 | -0.015 | -0.0482 | No | ||
147 | FHOD1 | 2680279 | 14016 | -0.016 | -0.0515 | No | ||
148 | PCDH9 | 2100136 | 14192 | -0.019 | -0.0604 | No | ||
149 | USP2 | 1190292 1240253 4850035 | 14290 | -0.021 | -0.0651 | No | ||
150 | NLN | 1450576 5870575 | 14312 | -0.021 | -0.0657 | No | ||
151 | IBRDC2 | 5130041 | 14395 | -0.023 | -0.0695 | No | ||
152 | LAPTM5 | 5550372 | 14519 | -0.026 | -0.0754 | No | ||
153 | PITPNC1 | 3990017 | 14771 | -0.034 | -0.0881 | No | ||
154 | PIM2 | 840136 5720692 7100577 | 14794 | -0.034 | -0.0883 | No | ||
155 | APBA2BP | 5700341 | 14904 | -0.039 | -0.0931 | No | ||
156 | CASK | 2340215 3290576 6770215 | 14939 | -0.041 | -0.0937 | No | ||
157 | ROCK2 | 1780035 5720025 | 15017 | -0.044 | -0.0967 | No | ||
158 | VDR | 130156 510438 | 15169 | -0.052 | -0.1034 | No | ||
159 | LTBP3 | 1190162 2650440 6520451 | 15196 | -0.053 | -0.1032 | No | ||
160 | COL27A1 | 1740390 | 15200 | -0.053 | -0.1019 | No | ||
161 | MCART1 | 5270059 | 15304 | -0.060 | -0.1058 | No | ||
162 | SORT1 | 1850242 2320632 3870537 | 15363 | -0.064 | -0.1071 | No | ||
163 | SCOC | 610048 2230053 | 15370 | -0.064 | -0.1056 | No | ||
164 | RIN1 | 510593 | 15581 | -0.078 | -0.1147 | No | ||
165 | MAP2K1 | 840739 | 15876 | -0.103 | -0.1277 | No | ||
166 | APOBEC1 | 4610022 | 16038 | -0.121 | -0.1330 | No | ||
167 | CMAS | 2190129 | 16073 | -0.123 | -0.1313 | No | ||
168 | PROSC | 380484 | 16107 | -0.127 | -0.1295 | No | ||
169 | RAB22A | 110500 3830707 | 16144 | -0.130 | -0.1277 | No | ||
170 | ABI3 | 1740563 | 16250 | -0.146 | -0.1292 | No | ||
171 | LAMC1 | 4730025 | 16293 | -0.153 | -0.1271 | No | ||
172 | SLC16A6 | 1690156 | 16569 | -0.200 | -0.1363 | No | ||
173 | CALM3 | 3390288 | 16601 | -0.206 | -0.1320 | No | ||
174 | HCFC1 | 2260008 | 16657 | -0.219 | -0.1287 | No | ||
175 | FLI1 | 3990142 | 16684 | -0.225 | -0.1237 | No | ||
176 | USP3 | 2060332 | 16754 | -0.242 | -0.1205 | No | ||
177 | CYFIP1 | 5690082 | 17246 | -0.370 | -0.1365 | No | ||
178 | PKN3 | 2260538 | 17352 | -0.403 | -0.1307 | No | ||
179 | ATP6V1A | 6590242 | 17388 | -0.416 | -0.1207 | No | ||
180 | SLC20A1 | 6420014 | 17395 | -0.418 | -0.1090 | No | ||
181 | ICK | 1580746 3140021 | 17495 | -0.454 | -0.1013 | No | ||
182 | WBP5 | 7050563 | 17521 | -0.462 | -0.0895 | No | ||
183 | EIF4G1 | 4070446 | 17543 | -0.470 | -0.0771 | No | ||
184 | TRIM8 | 6130441 | 17683 | -0.528 | -0.0695 | No | ||
185 | XPOT | 7050184 | 17807 | -0.578 | -0.0596 | No | ||
186 | TOB1 | 4150138 | 17941 | -0.646 | -0.0483 | No | ||
187 | PDAP1 | 1410735 | 18081 | -0.739 | -0.0347 | No | ||
188 | PPP2CA | 3990113 | 18202 | -0.833 | -0.0173 | No | ||
189 | TCF12 | 3610324 7000156 | 18494 | -1.384 | 0.0066 | No |