Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | GTACTGT,MIR-101 |
Enrichment Score (ES) | -0.68405783 |
Normalized Enrichment Score (NES) | -1.8054825 |
Nominal p-value | 0.0 |
FDR q-value | 8.3827495E-4 |
FWER p-Value | 0.0010 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ETV5 | 110017 | 145 | 1.443 | 0.0257 | No | ||
2 | UBE2Q1 | 610348 2350114 4210717 | 186 | 1.259 | 0.0529 | No | ||
3 | SMARCD1 | 3060193 3850184 6400369 | 811 | 0.536 | 0.0316 | No | ||
4 | JUNB | 4230048 | 1713 | 0.291 | -0.0105 | No | ||
5 | BZW2 | 940079 | 2495 | 0.174 | -0.0489 | No | ||
6 | BCL9 | 7100112 | 2591 | 0.163 | -0.0502 | No | ||
7 | BAZ2A | 730184 | 2653 | 0.153 | -0.0500 | No | ||
8 | LASS2 | 4120086 6770358 | 2767 | 0.137 | -0.0529 | No | ||
9 | RAPH1 | 6760411 | 2869 | 0.127 | -0.0554 | No | ||
10 | FEM1C | 60300 6130717 6980164 | 2901 | 0.125 | -0.0542 | No | ||
11 | FBXW7 | 4210338 7050280 | 3099 | 0.104 | -0.0625 | No | ||
12 | HAS2 | 5360181 | 3114 | 0.103 | -0.0608 | No | ||
13 | IGFBP5 | 2360592 | 3155 | 0.100 | -0.0607 | No | ||
14 | DDIT4 | 2570408 | 3216 | 0.095 | -0.0617 | No | ||
15 | DLG5 | 450215 | 3381 | 0.084 | -0.0686 | No | ||
16 | KCNH7 | 7510068 | 3514 | 0.077 | -0.0740 | No | ||
17 | MAGI1 | 6510500 1990239 4670471 | 3809 | 0.063 | -0.0885 | No | ||
18 | CPEB2 | 4760338 | 3815 | 0.063 | -0.0873 | No | ||
19 | CDYL | 4200142 4730397 6060400 | 3857 | 0.061 | -0.0881 | No | ||
20 | ING3 | 110438 2060390 | 3989 | 0.056 | -0.0939 | No | ||
21 | FLRT2 | 4200035 | 4066 | 0.054 | -0.0967 | No | ||
22 | SOX9 | 5720681 | 4119 | 0.052 | -0.0984 | No | ||
23 | SOCS5 | 3830398 7100093 | 4188 | 0.050 | -0.1009 | No | ||
24 | PREI3 | 3170066 3440075 6370427 | 4220 | 0.050 | -0.1014 | No | ||
25 | ACCN2 | 6450465 | 4315 | 0.047 | -0.1054 | No | ||
26 | NEUROD1 | 3060619 | 4321 | 0.047 | -0.1046 | No | ||
27 | RNF38 | 1940746 3140133 3840601 | 4560 | 0.040 | -0.1165 | No | ||
28 | TSC22D1 | 1340739 6040181 | 4752 | 0.036 | -0.1261 | No | ||
29 | PDE4A | 1190619 1340129 5720100 6370035 | 4754 | 0.036 | -0.1253 | No | ||
30 | MAK | 2940706 | 4757 | 0.036 | -0.1245 | No | ||
31 | RIPK5 | 1230647 1340114 | 4765 | 0.036 | -0.1241 | No | ||
32 | FOS | 1850315 | 4806 | 0.035 | -0.1254 | No | ||
33 | COL10A1 | 2360307 | 5104 | 0.030 | -0.1408 | No | ||
34 | MYST2 | 4540494 | 5386 | 0.025 | -0.1555 | No | ||
35 | DCBLD2 | 5890333 | 5432 | 0.025 | -0.1573 | No | ||
36 | LRRN1 | 3290154 | 5484 | 0.024 | -0.1595 | No | ||
37 | DNMT3A | 4050068 4810717 | 5549 | 0.024 | -0.1625 | No | ||
38 | BTBD3 | 1980041 2510577 3190053 4200746 | 5617 | 0.023 | -0.1656 | No | ||
39 | DDEF1 | 1170411 4070465 | 5962 | 0.019 | -0.1838 | No | ||
40 | ZFHX4 | 6110167 | 6149 | 0.018 | -0.1935 | No | ||
41 | ATRX | 2340039 3610132 4210373 | 6152 | 0.018 | -0.1932 | No | ||
42 | CDH5 | 5340487 | 6304 | 0.016 | -0.2010 | No | ||
43 | ATXN1 | 5550156 | 6310 | 0.016 | -0.2009 | No | ||
44 | FZD4 | 1580520 | 6643 | 0.014 | -0.2186 | No | ||
45 | CPEB3 | 3940164 | 7386 | 0.010 | -0.2586 | No | ||
46 | TMEFF1 | 2680100 | 7542 | 0.009 | -0.2668 | No | ||
47 | TRIB1 | 2320435 | 7666 | 0.009 | -0.2732 | No | ||
48 | FLRT3 | 70685 2760497 6040519 | 7758 | 0.008 | -0.2780 | No | ||
49 | CDH11 | 1230133 2100180 4610110 | 7792 | 0.008 | -0.2796 | No | ||
50 | FBN2 | 50435 | 7862 | 0.008 | -0.2831 | No | ||
51 | NEGR1 | 1940731 5130170 | 8012 | 0.008 | -0.2910 | No | ||
52 | SIX4 | 6760022 | 8040 | 0.007 | -0.2923 | No | ||
53 | USP38 | 4590095 | 8345 | 0.006 | -0.3087 | No | ||
54 | PRKAA1 | 510156 | 8616 | 0.006 | -0.3232 | No | ||
55 | ROBO2 | 450136 | 8787 | 0.005 | -0.3323 | No | ||
56 | POGZ | 870348 7040286 | 8791 | 0.005 | -0.3324 | No | ||
57 | EYA1 | 1450278 5220390 | 8793 | 0.005 | -0.3323 | No | ||
58 | KHDRBS3 | 2120154 | 8869 | 0.005 | -0.3363 | No | ||
59 | TEAD3 | 2320142 | 9019 | 0.004 | -0.3442 | No | ||
60 | CLCN3 | 510195 780176 1660093 3830372 | 9290 | 0.003 | -0.3588 | No | ||
61 | ADAMTS10 | 730563 | 9316 | 0.003 | -0.3601 | No | ||
62 | TGFBR1 | 1400148 4280020 6550711 | 9353 | 0.003 | -0.3620 | No | ||
63 | THRB | 1780673 | 9623 | 0.003 | -0.3765 | No | ||
64 | NRK | 4590609 | 9726 | 0.002 | -0.3820 | No | ||
65 | FBXW11 | 6450632 | 9783 | 0.002 | -0.3850 | No | ||
66 | PCDH8 | 2360047 4200452 | 10061 | 0.002 | -0.3999 | No | ||
67 | GLRA2 | 7000019 | 10134 | 0.001 | -0.4038 | No | ||
68 | PACRG | 3140053 | 10304 | 0.001 | -0.4130 | No | ||
69 | CCNJ | 870047 | 10416 | 0.001 | -0.4190 | No | ||
70 | TAL1 | 7040239 | 10620 | 0.000 | -0.4300 | No | ||
71 | FGA | 4210056 5220239 | 10746 | -0.000 | -0.4368 | No | ||
72 | PUM2 | 4200441 5910446 | 10921 | -0.001 | -0.4462 | No | ||
73 | EXOC5 | 7000711 | 11005 | -0.001 | -0.4507 | No | ||
74 | PALM2 | 4120068 7100398 | 11263 | -0.002 | -0.4646 | No | ||
75 | RAB5A | 6520324 | 11472 | -0.002 | -0.4758 | No | ||
76 | CTTNBP2 | 2650167 | 11766 | -0.003 | -0.4916 | No | ||
77 | HNRPF | 670138 | 11871 | -0.003 | -0.4972 | No | ||
78 | PRKCE | 5700053 | 12122 | -0.004 | -0.5107 | No | ||
79 | DR1 | 5860750 | 12283 | -0.005 | -0.5192 | No | ||
80 | DDX3Y | 1580278 4200519 | 12364 | -0.005 | -0.5235 | No | ||
81 | UBE2D1 | 1850400 | 12396 | -0.005 | -0.5250 | No | ||
82 | FZD6 | 360288 | 12504 | -0.005 | -0.5307 | No | ||
83 | LRRC4 | 3850041 | 12521 | -0.006 | -0.5314 | No | ||
84 | PLXNB1 | 6220273 | 12536 | -0.006 | -0.5321 | No | ||
85 | ASPN | 2450021 | 12562 | -0.006 | -0.5333 | No | ||
86 | PRPF4B | 940181 2570300 | 12696 | -0.006 | -0.5404 | No | ||
87 | HOXD4 | 5900301 | 12777 | -0.007 | -0.5446 | No | ||
88 | MPPE1 | 5080364 7050739 | 12828 | -0.007 | -0.5471 | No | ||
89 | NUDT11 | 3840239 | 12831 | -0.007 | -0.5471 | No | ||
90 | NDFIP1 | 1980402 | 12963 | -0.008 | -0.5540 | No | ||
91 | PTGS2 | 2510301 3170369 | 12973 | -0.008 | -0.5543 | No | ||
92 | PPFIA4 | 630446 | 13048 | -0.008 | -0.5581 | No | ||
93 | MYRIP | 1580471 | 13393 | -0.010 | -0.5766 | No | ||
94 | SMARCA1 | 4230315 | 13422 | -0.010 | -0.5778 | No | ||
95 | QKI | 5220093 6130044 | 13435 | -0.010 | -0.5783 | No | ||
96 | LRRN3 | 1450133 | 13450 | -0.010 | -0.5788 | No | ||
97 | RGS1 | 4060347 4540181 | 13462 | -0.010 | -0.5791 | No | ||
98 | MMP15 | 5900717 | 13631 | -0.012 | -0.5880 | No | ||
99 | CAV3 | 1770519 | 13637 | -0.012 | -0.5880 | No | ||
100 | ZCCHC2 | 460592 | 13720 | -0.013 | -0.5921 | No | ||
101 | PLCG1 | 6020369 | 13898 | -0.015 | -0.6014 | No | ||
102 | MARK1 | 450484 | 14010 | -0.016 | -0.6070 | No | ||
103 | KIF1A | 450632 | 14099 | -0.017 | -0.6114 | No | ||
104 | ABCC5 | 2100600 5050692 | 14134 | -0.018 | -0.6128 | No | ||
105 | ADCY6 | 450364 6290670 6940286 | 14168 | -0.018 | -0.6142 | No | ||
106 | PURG | 1190593 | 14393 | -0.023 | -0.6258 | No | ||
107 | SLC39A10 | 4150347 | 14512 | -0.026 | -0.6316 | No | ||
108 | USP47 | 2640497 | 14584 | -0.028 | -0.6348 | No | ||
109 | ERBB2IP | 580253 1090672 | 14632 | -0.029 | -0.6367 | No | ||
110 | SLC1A1 | 520372 6420059 | 14694 | -0.031 | -0.6393 | No | ||
111 | RASD2 | 3360010 | 14737 | -0.033 | -0.6408 | No | ||
112 | CDK6 | 4920253 | 14772 | -0.034 | -0.6418 | No | ||
113 | RIN2 | 2450184 | 14801 | -0.035 | -0.6426 | No | ||
114 | STAG2 | 4540132 | 14887 | -0.038 | -0.6463 | No | ||
115 | CEBPA | 5690519 | 14947 | -0.041 | -0.6485 | No | ||
116 | SOX11 | 610279 | 14979 | -0.043 | -0.6492 | No | ||
117 | SPRED1 | 6940706 | 14983 | -0.043 | -0.6484 | No | ||
118 | NLK | 2030010 2450041 | 15015 | -0.044 | -0.6490 | No | ||
119 | BICD2 | 1090411 | 15111 | -0.049 | -0.6530 | No | ||
120 | PDE4D | 2470528 6660014 | 15170 | -0.052 | -0.6550 | No | ||
121 | LRRFIP2 | 670575 730152 6590438 | 15205 | -0.054 | -0.6556 | No | ||
122 | PAPOLG | 2470400 | 15279 | -0.058 | -0.6582 | No | ||
123 | DUSP1 | 6860121 | 15329 | -0.061 | -0.6594 | No | ||
124 | AEBP2 | 2970603 | 15344 | -0.062 | -0.6587 | No | ||
125 | GPR85 | 5130750 5910020 | 15609 | -0.080 | -0.6712 | No | ||
126 | ANKRD17 | 2120402 3850035 6400044 | 15674 | -0.085 | -0.6727 | No | ||
127 | STC1 | 360161 | 15685 | -0.086 | -0.6712 | No | ||
128 | DAG1 | 460053 610341 | 15740 | -0.091 | -0.6720 | No | ||
129 | PANK3 | 3060687 | 15845 | -0.099 | -0.6754 | No | ||
130 | DOT1L | 3850068 | 15961 | -0.112 | -0.6790 | Yes | ||
131 | DYRK1A | 3190181 | 15981 | -0.115 | -0.6774 | Yes | ||
132 | TXNDC4 | 450537 | 16058 | -0.122 | -0.6786 | Yes | ||
133 | LMNB1 | 5890292 6020008 | 16075 | -0.124 | -0.6766 | Yes | ||
134 | SGPL1 | 4480059 | 16108 | -0.127 | -0.6754 | Yes | ||
135 | CACNB2 | 1500095 7330707 | 16154 | -0.132 | -0.6748 | Yes | ||
136 | ZFAND3 | 2760504 | 16199 | -0.139 | -0.6739 | Yes | ||
137 | SLC30A7 | 2230463 | 16204 | -0.140 | -0.6709 | Yes | ||
138 | CDK5R1 | 3870161 | 16346 | -0.161 | -0.6748 | Yes | ||
139 | REV3L | 1090717 | 16350 | -0.161 | -0.6712 | Yes | ||
140 | TERF2 | 3840044 | 16389 | -0.166 | -0.6694 | Yes | ||
141 | UBE2A | 4010563 | 16394 | -0.167 | -0.6657 | Yes | ||
142 | SFRS5 | 3450176 6350008 | 16484 | -0.186 | -0.6662 | Yes | ||
143 | ZNF24 | 3830750 | 16814 | -0.257 | -0.6781 | Yes | ||
144 | SOCS2 | 4760692 | 16870 | -0.269 | -0.6748 | Yes | ||
145 | CBL | 6380068 | 16908 | -0.276 | -0.6704 | Yes | ||
146 | PURB | 5360138 | 16916 | -0.280 | -0.6642 | Yes | ||
147 | UBE2D3 | 3190452 | 16917 | -0.280 | -0.6577 | Yes | ||
148 | APP | 2510053 | 16987 | -0.298 | -0.6545 | Yes | ||
149 | TLK2 | 1170161 | 17039 | -0.313 | -0.6500 | Yes | ||
150 | RBBP7 | 430113 450450 2370309 | 17096 | -0.331 | -0.6453 | Yes | ||
151 | BCL2L11 | 780044 4200601 | 17172 | -0.349 | -0.6412 | Yes | ||
152 | OGT | 2360131 4610333 | 17176 | -0.350 | -0.6333 | Yes | ||
153 | PIP5K1C | 5890164 6510148 | 17243 | -0.369 | -0.6282 | Yes | ||
154 | MTMR2 | 2260148 3990139 | 17301 | -0.384 | -0.6224 | Yes | ||
155 | GNB1 | 2120397 | 17307 | -0.386 | -0.6137 | Yes | ||
156 | PHLDA1 | 2450020 | 17342 | -0.399 | -0.6062 | Yes | ||
157 | NACA | 520326 5890673 | 17343 | -0.400 | -0.5969 | Yes | ||
158 | ICK | 1580746 3140021 | 17495 | -0.454 | -0.5945 | Yes | ||
159 | RRM1 | 4150433 | 17568 | -0.484 | -0.5872 | Yes | ||
160 | PPFIA1 | 430176 3610524 | 17603 | -0.497 | -0.5774 | Yes | ||
161 | EZH2 | 6130605 6380524 | 17642 | -0.510 | -0.5676 | Yes | ||
162 | SLC19A2 | 6200750 | 17768 | -0.562 | -0.5613 | Yes | ||
163 | RAB1A | 2370671 | 17825 | -0.589 | -0.5506 | Yes | ||
164 | RXRB | 1780040 5340438 | 17827 | -0.589 | -0.5369 | Yes | ||
165 | RANBP9 | 4670685 | 17903 | -0.626 | -0.5264 | Yes | ||
166 | UBE2D2 | 4590671 6510446 | 17960 | -0.656 | -0.5142 | Yes | ||
167 | EED | 2320373 | 18056 | -0.715 | -0.5027 | Yes | ||
168 | DDX3X | 2190020 | 18098 | -0.751 | -0.4874 | Yes | ||
169 | KPNB1 | 1690138 | 18119 | -0.762 | -0.4707 | Yes | ||
170 | SRPK2 | 6380341 | 18176 | -0.812 | -0.4549 | Yes | ||
171 | RAP2C | 1690132 | 18260 | -0.898 | -0.4384 | Yes | ||
172 | MBNL1 | 2640762 7100048 | 18303 | -0.941 | -0.4188 | Yes | ||
173 | JDP2 | 2360500 | 18305 | -0.944 | -0.3968 | Yes | ||
174 | TULP4 | 2320364 | 18381 | -1.050 | -0.3765 | Yes | ||
175 | SPOP | 450035 | 18384 | -1.060 | -0.3519 | Yes | ||
176 | WSB1 | 870563 | 18395 | -1.079 | -0.3273 | Yes | ||
177 | STK4 | 2640152 | 18411 | -1.123 | -0.3019 | Yes | ||
178 | RAP1B | 3710138 | 18424 | -1.148 | -0.2758 | Yes | ||
179 | AP3S1 | 5570044 | 18425 | -1.149 | -0.2491 | Yes | ||
180 | CTCF | 5340017 | 18455 | -1.243 | -0.2217 | Yes | ||
181 | EMP1 | 4120438 | 18556 | -1.755 | -0.1862 | Yes | ||
182 | GJA1 | 5220731 | 18585 | -2.218 | -0.1360 | Yes | ||
183 | ARID1A | 2630022 1690551 4810110 | 18616 | -5.910 | 0.0000 | Yes |