Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | -0.612987 |
Normalized Enrichment Score (NES) | -1.6642733 |
Nominal p-value | 0.0 |
FDR q-value | 0.012380172 |
FWER p-Value | 0.119 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PSEN1 | 130403 2030647 6100603 | 35 | 2.626 | 0.0505 | No | ||
2 | ACOT7 | 730735 1400176 7050053 | 79 | 1.939 | 0.0868 | No | ||
3 | HRBL | 1850102 3830253 4780176 | 257 | 1.075 | 0.0986 | No | ||
4 | STAT5A | 2680458 | 831 | 0.525 | 0.0779 | No | ||
5 | RTN4RL1 | 2630368 | 928 | 0.486 | 0.0824 | No | ||
6 | BACE1 | 2650438 | 1252 | 0.386 | 0.0725 | No | ||
7 | ATF5 | 5670685 | 1332 | 0.368 | 0.0755 | No | ||
8 | PPT2 | 2340059 3450148 | 1772 | 0.280 | 0.0572 | No | ||
9 | ST3GAL3 | 2810601 | 2161 | 0.222 | 0.0406 | No | ||
10 | EPN1 | 4060725 | 2163 | 0.221 | 0.0449 | No | ||
11 | DOLPP1 | 4780619 6400053 | 2317 | 0.198 | 0.0406 | No | ||
12 | SON | 3120148 5860239 7040403 | 2364 | 0.192 | 0.0419 | No | ||
13 | SLC25A3 | 670112 | 2378 | 0.190 | 0.0449 | No | ||
14 | SERF2 | 5720010 | 2464 | 0.179 | 0.0439 | No | ||
15 | DEK | 1050451 4560037 | 2802 | 0.134 | 0.0282 | No | ||
16 | AMPD2 | 630093 1170070 | 2830 | 0.131 | 0.0294 | No | ||
17 | SLC6A9 | 2470520 | 2887 | 0.126 | 0.0288 | No | ||
18 | TOP1 | 770471 4060632 6650324 | 2912 | 0.123 | 0.0300 | No | ||
19 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 2935 | 0.120 | 0.0312 | No | ||
20 | PPP2R2A | 2900014 5700575 | 2973 | 0.116 | 0.0315 | No | ||
21 | CDC42BPB | 6350037 | 3056 | 0.109 | 0.0292 | No | ||
22 | HMG20A | 4590113 | 3141 | 0.101 | 0.0266 | No | ||
23 | DLC1 | 1090632 6450594 | 3530 | 0.076 | 0.0071 | No | ||
24 | HIC2 | 4010433 | 3558 | 0.075 | 0.0071 | No | ||
25 | LRRC8A | 2510193 | 3679 | 0.069 | 0.0019 | No | ||
26 | TSC1 | 1850672 | 3686 | 0.068 | 0.0030 | No | ||
27 | MOBKL2B | 940128 | 3753 | 0.065 | 0.0007 | No | ||
28 | SPRYD3 | 50403 | 3764 | 0.065 | 0.0014 | No | ||
29 | PEX5 | 1240746 1570092 2510487 | 3765 | 0.065 | 0.0027 | No | ||
30 | SIPA1L2 | 4850731 | 3783 | 0.064 | 0.0030 | No | ||
31 | EPHA2 | 5890056 | 3888 | 0.060 | -0.0014 | No | ||
32 | PAPPA | 4230463 | 4079 | 0.054 | -0.0107 | No | ||
33 | SEMA6A | 2690138 3060021 | 4083 | 0.053 | -0.0098 | No | ||
34 | SYT4 | 5080193 | 4110 | 0.053 | -0.0102 | No | ||
35 | KIF1C | 2480484 | 4175 | 0.051 | -0.0126 | No | ||
36 | ZCCHC3 | 580438 1990035 4780278 | 4372 | 0.045 | -0.0224 | No | ||
37 | TM9SF4 | 450538 1050093 4210112 | 4700 | 0.037 | -0.0394 | No | ||
38 | TTYH2 | 1450397 3870100 6550347 | 4717 | 0.037 | -0.0395 | No | ||
39 | PTPRG | 2650524 1340022 | 4811 | 0.035 | -0.0439 | No | ||
40 | STAT5B | 6200026 | 5048 | 0.031 | -0.0561 | No | ||
41 | PLAG1 | 1450142 3870139 6520039 | 5161 | 0.029 | -0.0616 | No | ||
42 | SOX5 | 2370576 2900167 3190128 5050528 | 5174 | 0.029 | -0.0617 | No | ||
43 | MDGA1 | 1170139 | 5330 | 0.026 | -0.0696 | No | ||
44 | CYP26B1 | 2630142 | 5349 | 0.026 | -0.0701 | No | ||
45 | ELF2 | 1690014 2480132 3060180 3190504 | 5369 | 0.026 | -0.0706 | No | ||
46 | EPHA7 | 1190288 4010278 | 5441 | 0.025 | -0.0740 | No | ||
47 | ELAVL2 | 360181 | 5547 | 0.024 | -0.0792 | No | ||
48 | FRMD4A | 2190176 | 5807 | 0.021 | -0.0929 | No | ||
49 | RAB38 | 2970735 | 5933 | 0.020 | -0.0993 | No | ||
50 | USP9X | 130435 2370735 3120338 | 5977 | 0.019 | -0.1012 | No | ||
51 | CXCL12 | 580546 4150750 4570068 | 5997 | 0.019 | -0.1019 | No | ||
52 | SLC17A6 | 4210576 | 6067 | 0.018 | -0.1053 | No | ||
53 | CPD | 5360403 5860685 | 6182 | 0.017 | -0.1111 | No | ||
54 | HOXB5 | 2900538 | 6224 | 0.017 | -0.1130 | No | ||
55 | ATXN1 | 5550156 | 6310 | 0.016 | -0.1173 | No | ||
56 | LHX6 | 2360731 3360397 | 6512 | 0.015 | -0.1279 | No | ||
57 | MYT1L | 5670369 6660403 | 6802 | 0.013 | -0.1434 | No | ||
58 | KLHL18 | 4560075 | 6809 | 0.013 | -0.1435 | No | ||
59 | BRUNOL6 | 6840373 | 6935 | 0.012 | -0.1500 | No | ||
60 | PHLPP | 3440563 | 7008 | 0.012 | -0.1537 | No | ||
61 | NRP2 | 4070400 5860041 6650446 | 7033 | 0.012 | -0.1548 | No | ||
62 | STK35 | 2360121 | 7110 | 0.011 | -0.1587 | No | ||
63 | PHYHIPL | 2360706 3840692 | 7241 | 0.011 | -0.1656 | No | ||
64 | POU4F1 | 2260315 | 7302 | 0.010 | -0.1686 | No | ||
65 | STAT4 | 1660373 3130019 | 7406 | 0.010 | -0.1740 | No | ||
66 | PITX2 | 870537 2690139 | 7494 | 0.009 | -0.1786 | No | ||
67 | TMEFF1 | 2680100 | 7542 | 0.009 | -0.1809 | No | ||
68 | HOXC13 | 4070722 | 8081 | 0.007 | -0.2101 | No | ||
69 | DIXDC1 | 6980435 | 8253 | 0.007 | -0.2192 | No | ||
70 | KHDRBS2 | 3520717 | 8382 | 0.006 | -0.2261 | No | ||
71 | ACVR2A | 6110647 | 8395 | 0.006 | -0.2266 | No | ||
72 | TIAL1 | 4150048 6510605 | 8678 | 0.005 | -0.2418 | No | ||
73 | LPP | 1660541 | 8740 | 0.005 | -0.2450 | No | ||
74 | NFASC | 1940619 2470156 4590168 6840524 | 8751 | 0.005 | -0.2455 | No | ||
75 | WDFY3 | 3610041 4560333 4570273 | 8760 | 0.005 | -0.2458 | No | ||
76 | FOXA1 | 3710609 | 8803 | 0.005 | -0.2480 | No | ||
77 | HLF | 2370113 | 8885 | 0.005 | -0.2523 | No | ||
78 | PAFAH1B2 | 5360546 6860672 | 9200 | 0.004 | -0.2693 | No | ||
79 | CSF3 | 2230193 6660707 | 9346 | 0.003 | -0.2771 | No | ||
80 | ITSN1 | 2640577 | 9380 | 0.003 | -0.2788 | No | ||
81 | MTSS1 | 780435 2370114 | 9421 | 0.003 | -0.2810 | No | ||
82 | RARB | 430139 1410138 | 9600 | 0.003 | -0.2906 | No | ||
83 | THRB | 1780673 | 9623 | 0.003 | -0.2917 | No | ||
84 | CHES1 | 4570121 5700162 | 9627 | 0.003 | -0.2918 | No | ||
85 | LYPLA1 | 4480373 5570551 | 9804 | 0.002 | -0.3014 | No | ||
86 | TRHDE | 1690068 | 9807 | 0.002 | -0.3014 | No | ||
87 | GPM6B | 6220458 | 9951 | 0.002 | -0.3092 | No | ||
88 | PCDH8 | 2360047 4200452 | 10061 | 0.002 | -0.3151 | No | ||
89 | SPG3A | 2760091 3120170 | 10230 | 0.001 | -0.3242 | No | ||
90 | HOXA11 | 6980133 | 10256 | 0.001 | -0.3255 | No | ||
91 | DDX5 | 940021 2630338 3440148 | 10260 | 0.001 | -0.3257 | No | ||
92 | B3GNT1 | 2350446 | 10267 | 0.001 | -0.3260 | No | ||
93 | MMP16 | 2680139 | 10269 | 0.001 | -0.3260 | No | ||
94 | SP4 | 3850176 | 10522 | 0.000 | -0.3397 | No | ||
95 | TTR | 4150072 | 10531 | 0.000 | -0.3401 | No | ||
96 | ZFR | 5910647 | 10559 | 0.000 | -0.3416 | No | ||
97 | LENG8 | 3130731 | 10637 | 0.000 | -0.3458 | No | ||
98 | PCTK2 | 5700673 | 10823 | -0.000 | -0.3558 | No | ||
99 | NRXN1 | 460408 5340270 6370066 | 10842 | -0.000 | -0.3568 | No | ||
100 | SRC | 580132 | 10877 | -0.001 | -0.3586 | No | ||
101 | EXOC5 | 7000711 | 11005 | -0.001 | -0.3655 | No | ||
102 | CALCR | 1690494 | 11412 | -0.002 | -0.3875 | No | ||
103 | SNF1LK | 6110403 | 11550 | -0.002 | -0.3950 | No | ||
104 | CLASP2 | 2510139 | 11663 | -0.003 | -0.4010 | No | ||
105 | HNRPF | 670138 | 11871 | -0.003 | -0.4122 | No | ||
106 | SLC16A7 | 2320672 | 12140 | -0.004 | -0.4267 | No | ||
107 | DR1 | 5860750 | 12283 | -0.005 | -0.4343 | No | ||
108 | ARPC5 | 1740411 3450300 | 12353 | -0.005 | -0.4380 | No | ||
109 | TGFB2 | 4920292 | 12411 | -0.005 | -0.4410 | No | ||
110 | NR2C2 | 6100097 | 12442 | -0.005 | -0.4425 | No | ||
111 | OLFM1 | 3360161 5570066 | 12529 | -0.006 | -0.4470 | No | ||
112 | CSNK2A1 | 1580577 | 12794 | -0.007 | -0.4613 | No | ||
113 | SEPT7 | 2760685 | 12907 | -0.007 | -0.4672 | No | ||
114 | RBM7 | 5890348 | 12911 | -0.007 | -0.4672 | No | ||
115 | ESRRG | 4010181 | 12954 | -0.007 | -0.4694 | No | ||
116 | ATXN7 | 1450435 | 13254 | -0.009 | -0.4854 | No | ||
117 | RAD23B | 2190671 | 13365 | -0.010 | -0.4912 | No | ||
118 | MYRIP | 1580471 | 13393 | -0.010 | -0.4925 | No | ||
119 | QKI | 5220093 6130044 | 13435 | -0.010 | -0.4945 | No | ||
120 | KCNJ2 | 630019 | 13584 | -0.011 | -0.5023 | No | ||
121 | JUN | 840170 | 13604 | -0.011 | -0.5031 | No | ||
122 | WDR26 | 1090138 | 13648 | -0.012 | -0.5052 | No | ||
123 | UBE3A | 1240152 2690438 5860609 | 13717 | -0.013 | -0.5087 | No | ||
124 | PBEF1 | 1090278 | 13761 | -0.013 | -0.5108 | No | ||
125 | GRIN3A | 2370592 | 13778 | -0.013 | -0.5114 | No | ||
126 | DRD2 | 5890369 | 13866 | -0.014 | -0.5158 | No | ||
127 | STXBP1 | 360072 6220717 | 13909 | -0.015 | -0.5178 | No | ||
128 | STRN | 5570706 7050333 | 14055 | -0.017 | -0.5254 | No | ||
129 | DUSP3 | 1240129 6840215 | 14068 | -0.017 | -0.5257 | No | ||
130 | CSNK1A1 | 2340427 | 14088 | -0.017 | -0.5264 | No | ||
131 | DMWD | 770019 1690047 | 14170 | -0.018 | -0.5304 | No | ||
132 | PCDH9 | 2100136 | 14192 | -0.019 | -0.5312 | No | ||
133 | APBB2 | 5130403 | 14215 | -0.019 | -0.5320 | No | ||
134 | PTP4A1 | 130692 | 14223 | -0.019 | -0.5320 | No | ||
135 | SNAP91 | 3170056 5690520 | 14326 | -0.021 | -0.5371 | No | ||
136 | SPAG9 | 580497 2510180 4210685 | 14429 | -0.023 | -0.5422 | No | ||
137 | SLC1A1 | 520372 6420059 | 14694 | -0.031 | -0.5559 | No | ||
138 | GATA6 | 1770010 | 14779 | -0.034 | -0.5598 | No | ||
139 | RPH3AL | 70110 | 14812 | -0.035 | -0.5608 | No | ||
140 | FGFR2 | 4670601 5570402 6940377 | 14922 | -0.040 | -0.5660 | No | ||
141 | WDR44 | 130195 1050609 1570685 | 14950 | -0.041 | -0.5666 | No | ||
142 | SOX11 | 610279 | 14979 | -0.043 | -0.5673 | No | ||
143 | BICD2 | 1090411 | 15111 | -0.049 | -0.5734 | No | ||
144 | BAP1 | 3830131 | 15172 | -0.052 | -0.5756 | No | ||
145 | E2F3 | 50162 460180 | 15177 | -0.052 | -0.5748 | No | ||
146 | CNR1 | 6550494 6760497 | 15249 | -0.056 | -0.5776 | No | ||
147 | MARCH7 | 3800020 6620168 | 15268 | -0.057 | -0.5774 | No | ||
148 | CHD9 | 430037 2570129 5420398 | 15355 | -0.063 | -0.5808 | No | ||
149 | FBXL2 | 6450722 | 15510 | -0.073 | -0.5877 | No | ||
150 | YTHDF3 | 4540632 4670717 7040609 | 15571 | -0.077 | -0.5895 | No | ||
151 | TNS3 | 6380242 | 15582 | -0.078 | -0.5885 | No | ||
152 | THRAP2 | 4920600 | 15592 | -0.079 | -0.5874 | No | ||
153 | TCERG1 | 2350551 4540397 5220746 | 15762 | -0.092 | -0.5947 | No | ||
154 | PTGES3 | 2190440 2680524 | 15919 | -0.107 | -0.6011 | No | ||
155 | MYH10 | 2640673 | 15934 | -0.108 | -0.5997 | No | ||
156 | CALU | 2680403 3520056 4610348 5720176 6130121 | 16005 | -0.117 | -0.6011 | No | ||
157 | HIPK1 | 110193 | 16015 | -0.118 | -0.5993 | No | ||
158 | SLC39A9 | 3940348 | 16034 | -0.120 | -0.5979 | No | ||
159 | KPNA3 | 7040088 | 16100 | -0.126 | -0.5989 | No | ||
160 | CDC14A | 4050132 | 16158 | -0.133 | -0.5993 | No | ||
161 | TAF12 | 3710746 4920300 6180603 | 16258 | -0.147 | -0.6018 | No | ||
162 | MECP2 | 1940450 | 16365 | -0.163 | -0.6043 | No | ||
163 | ATP6V1B2 | 4060528 | 16526 | -0.193 | -0.6091 | Yes | ||
164 | FKBP5 | 2190048 | 16537 | -0.195 | -0.6058 | Yes | ||
165 | DNAJC13 | 4730091 | 16570 | -0.200 | -0.6035 | Yes | ||
166 | PLAGL2 | 1770148 | 16594 | -0.206 | -0.6007 | Yes | ||
167 | YWHAG | 3780341 | 16606 | -0.207 | -0.5972 | Yes | ||
168 | ARNTL | 3170463 | 16623 | -0.211 | -0.5938 | Yes | ||
169 | ARHGEF18 | 2120279 | 16633 | -0.214 | -0.5901 | Yes | ||
170 | ANKFY1 | 360309 5390021 | 16681 | -0.225 | -0.5881 | Yes | ||
171 | MIB1 | 3800537 | 16713 | -0.232 | -0.5852 | Yes | ||
172 | FUS | 4760619 | 16757 | -0.242 | -0.5827 | Yes | ||
173 | CSNK1G3 | 110450 | 16790 | -0.251 | -0.5794 | Yes | ||
174 | RTF1 | 2100735 | 16811 | -0.256 | -0.5754 | Yes | ||
175 | SIRT1 | 1190731 | 16815 | -0.257 | -0.5705 | Yes | ||
176 | HOXB4 | 540131 | 16867 | -0.269 | -0.5679 | Yes | ||
177 | SLC23A2 | 6660722 | 16904 | -0.276 | -0.5643 | Yes | ||
178 | CBL | 6380068 | 16908 | -0.276 | -0.5590 | Yes | ||
179 | GPC2 | 130647 | 16958 | -0.290 | -0.5559 | Yes | ||
180 | BHLHB2 | 7040603 | 16960 | -0.290 | -0.5501 | Yes | ||
181 | GRB2 | 6650398 | 16989 | -0.299 | -0.5457 | Yes | ||
182 | AK3L1 | 7100601 | 16999 | -0.300 | -0.5402 | Yes | ||
183 | YAF2 | 940053 | 17126 | -0.338 | -0.5403 | Yes | ||
184 | YTHDF2 | 4060332 4610279 | 17165 | -0.348 | -0.5355 | Yes | ||
185 | OGT | 2360131 4610333 | 17176 | -0.350 | -0.5290 | Yes | ||
186 | OLIG3 | 1050603 | 17204 | -0.356 | -0.5234 | Yes | ||
187 | CDC25A | 3800184 | 17296 | -0.382 | -0.5207 | Yes | ||
188 | KIF3A | 5050348 6650079 | 17303 | -0.385 | -0.5134 | Yes | ||
189 | ATP6V1A | 6590242 | 17388 | -0.416 | -0.5097 | Yes | ||
190 | SLC20A1 | 6420014 | 17395 | -0.418 | -0.5017 | Yes | ||
191 | CCNE2 | 3120537 | 17413 | -0.423 | -0.4942 | Yes | ||
192 | PDCD4 | 3360403 5690110 | 17447 | -0.436 | -0.4873 | Yes | ||
193 | OSBPL11 | 1770044 | 17574 | -0.486 | -0.4844 | Yes | ||
194 | TFRC | 4050551 | 17586 | -0.491 | -0.4752 | Yes | ||
195 | H2AFZ | 1470168 | 17670 | -0.522 | -0.4693 | Yes | ||
196 | MTPN | 3940167 | 17784 | -0.569 | -0.4641 | Yes | ||
197 | RBMS1 | 6400014 | 17915 | -0.633 | -0.4586 | Yes | ||
198 | RUNX1 | 3840711 | 17919 | -0.634 | -0.4461 | Yes | ||
199 | MAP2K4 | 5130133 | 17937 | -0.644 | -0.4342 | Yes | ||
200 | TRAM1 | 2340441 6620592 | 17982 | -0.667 | -0.4233 | Yes | ||
201 | CNP | 2260451 | 18000 | -0.681 | -0.4106 | Yes | ||
202 | ACACA | 2490612 2680369 | 18033 | -0.701 | -0.3984 | Yes | ||
203 | SIM2 | 2100044 | 18068 | -0.726 | -0.3858 | Yes | ||
204 | ATP1B1 | 3130594 | 18082 | -0.740 | -0.3718 | Yes | ||
205 | CDV3 | 1940577 | 18094 | -0.746 | -0.3575 | Yes | ||
206 | RNF44 | 5910692 | 18104 | -0.755 | -0.3429 | Yes | ||
207 | CUL3 | 1850520 | 18128 | -0.768 | -0.3289 | Yes | ||
208 | PPP1R15B | 2640280 5860082 | 18137 | -0.777 | -0.3138 | Yes | ||
209 | SUPT6H | 3170082 | 18163 | -0.801 | -0.2992 | Yes | ||
210 | PITPNB | 5130039 | 18165 | -0.802 | -0.2833 | Yes | ||
211 | FOXP1 | 6510433 | 18175 | -0.810 | -0.2676 | Yes | ||
212 | PPP2CA | 3990113 | 18202 | -0.833 | -0.2524 | Yes | ||
213 | CD47 | 1850603 | 18213 | -0.844 | -0.2361 | Yes | ||
214 | SFPQ | 4760110 | 18222 | -0.850 | -0.2196 | Yes | ||
215 | BRD3 | 6130672 | 18237 | -0.871 | -0.2030 | Yes | ||
216 | RABGAP1 | 5050397 | 18248 | -0.884 | -0.1860 | Yes | ||
217 | RAP2C | 1690132 | 18260 | -0.898 | -0.1687 | Yes | ||
218 | MBNL1 | 2640762 7100048 | 18303 | -0.941 | -0.1522 | Yes | ||
219 | APRIN | 2810050 | 18339 | -0.987 | -0.1344 | Yes | ||
220 | TULP4 | 2320364 | 18381 | -1.050 | -0.1157 | Yes | ||
221 | WSB1 | 870563 | 18395 | -1.079 | -0.0949 | Yes | ||
222 | ANP32E | 6510706 | 18458 | -1.249 | -0.0734 | Yes | ||
223 | ATP2A2 | 1090075 3990279 | 18482 | -1.356 | -0.0476 | Yes | ||
224 | PRKACB | 4210170 | 18485 | -1.364 | -0.0205 | Yes | ||
225 | TCF12 | 3610324 7000156 | 18494 | -1.384 | 0.0066 | Yes |