Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | -0.8343861 |
| Normalized Enrichment Score (NES) | -1.6689777 |
| Nominal p-value | 0.0021276595 |
| FDR q-value | 0.103096195 |
| FWER p-Value | 0.223 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RPA2 | 2760301 5420195 | 1771 | 0.280 | -0.0732 | No | ||
| 2 | ORC1L | 2370328 6110390 | 2462 | 0.179 | -0.0961 | No | ||
| 3 | MCM5 | 2680647 | 2877 | 0.127 | -0.1084 | No | ||
| 4 | MCM2 | 5050139 | 5911 | 0.020 | -0.2699 | No | ||
| 5 | RAD1 | 4200551 | 7540 | 0.009 | -0.3568 | No | ||
| 6 | MCM10 | 4920632 | 8085 | 0.007 | -0.3855 | No | ||
| 7 | CDC25C | 2570673 4760161 6520707 | 12598 | -0.006 | -0.6277 | No | ||
| 8 | ORC4L | 4230538 5550288 | 14561 | -0.027 | -0.7311 | No | ||
| 9 | CHEK1 | 50167 1940300 | 14602 | -0.028 | -0.7310 | No | ||
| 10 | RAD9B | 2320064 | 14746 | -0.033 | -0.7361 | No | ||
| 11 | ORC2L | 1990470 6510019 | 14795 | -0.035 | -0.7360 | No | ||
| 12 | MCM7 | 3290292 5220056 | 15883 | -0.103 | -0.7863 | No | ||
| 13 | MCM3 | 5570068 | 15925 | -0.107 | -0.7800 | No | ||
| 14 | CDC45L | 70537 3130114 | 16937 | -0.285 | -0.8118 | Yes | ||
| 15 | RFC3 | 1980600 | 17089 | -0.329 | -0.7939 | Yes | ||
| 16 | ORC5L | 1940133 1940711 | 17162 | -0.347 | -0.7704 | Yes | ||
| 17 | CDC25A | 3800184 | 17296 | -0.382 | -0.7474 | Yes | ||
| 18 | RPA1 | 360452 | 17702 | -0.539 | -0.7266 | Yes | ||
| 19 | RPA3 | 5700136 | 17986 | -0.672 | -0.6887 | Yes | ||
| 20 | HUS1 | 3440494 3800156 | 18214 | -0.845 | -0.6342 | Yes | ||
| 21 | RFC5 | 3800452 6020091 | 18380 | -1.048 | -0.5602 | Yes | ||
| 22 | RFC4 | 3800082 6840142 | 18471 | -1.314 | -0.4612 | Yes | ||
| 23 | CDC7 | 4060546 4850041 | 18483 | -1.359 | -0.3544 | Yes | ||
| 24 | MCM6 | 60092 540181 6510110 | 18488 | -1.370 | -0.2464 | Yes | ||
| 25 | CDK2 | 130484 2260301 4010088 5050110 | 18532 | -1.554 | -0.1260 | Yes | ||
| 26 | MCM4 | 2760673 5420711 | 18548 | -1.651 | 0.0037 | Yes |
