Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION |
| Enrichment Score (ES) | -0.84159034 |
| Normalized Enrichment Score (NES) | -1.6238651 |
| Nominal p-value | 0.008316008 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.946 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PF4 | 6130332 | 762 | 0.356 | 0.0176 | No | ||
| 2 | CDK6 | 4920253 | 2151 | 0.113 | -0.0384 | No | ||
| 3 | ZBTB16 | 3290022 | 2342 | 0.098 | -0.0325 | No | ||
| 4 | LDB1 | 5270601 | 2393 | 0.095 | -0.0195 | No | ||
| 5 | TWIST2 | 6760433 | 3268 | 0.050 | -0.0584 | No | ||
| 6 | TBX3 | 2570672 | 3581 | 0.040 | -0.0686 | No | ||
| 7 | NPHP3 | 2450497 7050731 | 4363 | 0.025 | -0.1065 | No | ||
| 8 | CALCA | 5860167 | 5551 | 0.014 | -0.1681 | No | ||
| 9 | SHH | 5570400 | 6670 | 0.008 | -0.2269 | No | ||
| 10 | NF1 | 6980433 | 9364 | -0.000 | -0.3718 | No | ||
| 11 | CARTPT | 6660687 | 10152 | -0.002 | -0.4138 | No | ||
| 12 | MAFB | 1230471 | 11277 | -0.005 | -0.4733 | No | ||
| 13 | IL4 | 6020537 | 11441 | -0.006 | -0.4811 | No | ||
| 14 | GPR98 | 6400647 | 11850 | -0.007 | -0.5018 | No | ||
| 15 | CNTN4 | 1780300 5570577 6370019 | 12371 | -0.010 | -0.5282 | No | ||
| 16 | EREG | 50519 4920129 | 12398 | -0.010 | -0.5280 | No | ||
| 17 | BMP4 | 380113 | 12935 | -0.013 | -0.5547 | No | ||
| 18 | NOTCH2 | 2570397 | 13080 | -0.014 | -0.5602 | No | ||
| 19 | SOCS5 | 3830398 7100093 | 13714 | -0.019 | -0.5911 | No | ||
| 20 | INHA | 6100102 | 14102 | -0.024 | -0.6080 | No | ||
| 21 | NOTCH4 | 2450040 6370707 | 15203 | -0.046 | -0.6596 | Yes | ||
| 22 | NOTCH1 | 3390114 | 18588 | -2.330 | -0.4582 | Yes | ||
| 23 | DTX1 | 5900372 | 18597 | -2.793 | 0.0010 | Yes |
