Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
Upregulated in class | wtNotch |
GeneSet | V$AP1FJ_Q2 |
Enrichment Score (ES) | -0.5337135 |
Normalized Enrichment Score (NES) | -1.374494 |
Nominal p-value | 0.01724138 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARRDC4 | 2810019 | 237 | 0.838 | 0.0205 | No | ||
2 | ETV5 | 110017 | 464 | 0.533 | 0.0295 | No | ||
3 | TCF12 | 3610324 7000156 | 488 | 0.504 | 0.0483 | No | ||
4 | PDAP1 | 1410735 | 549 | 0.458 | 0.0632 | No | ||
5 | USP3 | 2060332 | 575 | 0.440 | 0.0794 | No | ||
6 | CYFIP1 | 5690082 | 621 | 0.416 | 0.0935 | No | ||
7 | XPOT | 7050184 | 760 | 0.356 | 0.1002 | No | ||
8 | TOB1 | 4150138 | 922 | 0.306 | 0.1037 | No | ||
9 | LMNA | 520471 1500075 3190167 4210020 | 951 | 0.295 | 0.1139 | No | ||
10 | FKBP8 | 4060019 | 1327 | 0.218 | 0.1023 | No | ||
11 | TAGLN2 | 4560121 | 1342 | 0.216 | 0.1101 | No | ||
12 | SLC20A1 | 6420014 | 1603 | 0.170 | 0.1028 | No | ||
13 | ICK | 1580746 3140021 | 1680 | 0.160 | 0.1050 | No | ||
14 | VDR | 130156 510438 | 1682 | 0.159 | 0.1113 | No | ||
15 | LAPTM5 | 5550372 | 1948 | 0.130 | 0.1021 | No | ||
16 | PRKACA | 2640731 4050048 | 1953 | 0.129 | 0.1070 | No | ||
17 | CMAS | 2190129 | 2121 | 0.116 | 0.1026 | No | ||
18 | PPP2CA | 3990113 | 2208 | 0.108 | 0.1022 | No | ||
19 | LAMC1 | 4730025 | 2216 | 0.107 | 0.1061 | No | ||
20 | CALM3 | 3390288 | 2254 | 0.105 | 0.1083 | No | ||
21 | LTBP3 | 1190162 2650440 6520451 | 2288 | 0.103 | 0.1106 | No | ||
22 | SLC16A6 | 1690156 | 2371 | 0.096 | 0.1100 | No | ||
23 | USP2 | 1190292 1240253 4850035 | 2577 | 0.083 | 0.1021 | No | ||
24 | RAB22A | 110500 3830707 | 2738 | 0.074 | 0.0964 | No | ||
25 | AXIN2 | 3850131 | 3041 | 0.059 | 0.0823 | No | ||
26 | IRAK1 | 4120593 | 3340 | 0.047 | 0.0680 | No | ||
27 | DNAJB5 | 2900215 | 3515 | 0.042 | 0.0602 | No | ||
28 | MAP1A | 4920576 | 3622 | 0.039 | 0.0560 | No | ||
29 | RNF5 | 2760088 | 3689 | 0.037 | 0.0539 | No | ||
30 | LAMC2 | 450692 2680041 4200059 4670148 | 3696 | 0.037 | 0.0551 | No | ||
31 | RIN1 | 510593 | 3715 | 0.037 | 0.0556 | No | ||
32 | FARP1 | 5290102 7100341 | 3795 | 0.035 | 0.0527 | No | ||
33 | TRIM8 | 6130441 | 3901 | 0.032 | 0.0483 | No | ||
34 | FOS | 1850315 | 4052 | 0.030 | 0.0413 | No | ||
35 | IBRDC2 | 5130041 | 4082 | 0.029 | 0.0409 | No | ||
36 | PCDH9 | 2100136 | 4300 | 0.026 | 0.0302 | No | ||
37 | ISG20 | 1770750 | 4339 | 0.025 | 0.0291 | No | ||
38 | CMYA1 | 6900632 | 4608 | 0.022 | 0.0154 | No | ||
39 | PIM2 | 840136 5720692 7100577 | 4646 | 0.021 | 0.0143 | No | ||
40 | GGN | 1410528 4210082 5290170 | 4660 | 0.021 | 0.0144 | No | ||
41 | CLSTN3 | 2350685 | 4733 | 0.020 | 0.0113 | No | ||
42 | ZNF23 | 1090537 | 4748 | 0.020 | 0.0113 | No | ||
43 | SLC35E4 | 2370711 | 5042 | 0.017 | -0.0039 | No | ||
44 | AKT3 | 1580270 3290278 | 5297 | 0.015 | -0.0170 | No | ||
45 | KLHL1 | 6350021 | 5417 | 0.015 | -0.0229 | No | ||
46 | PITPNC1 | 3990017 | 5424 | 0.015 | -0.0227 | No | ||
47 | SDCBP | 460487 2190039 5270441 | 5553 | 0.014 | -0.0291 | No | ||
48 | SCRN1 | 6040025 6580019 | 5713 | 0.013 | -0.0372 | No | ||
49 | DSTN | 3140592 | 5920 | 0.012 | -0.0479 | No | ||
50 | TSNAXIP1 | 1770270 6180577 | 5927 | 0.012 | -0.0478 | No | ||
51 | MMP19 | 5080377 | 5932 | 0.011 | -0.0475 | No | ||
52 | SPTBN4 | 4150279 5270286 | 6007 | 0.011 | -0.0511 | No | ||
53 | ROCK2 | 1780035 5720025 | 6190 | 0.010 | -0.0606 | No | ||
54 | SHC3 | 2690398 | 6239 | 0.010 | -0.0628 | No | ||
55 | FLRT1 | 4540348 | 6376 | 0.009 | -0.0698 | No | ||
56 | AK5 | 6290348 | 6480 | 0.009 | -0.0750 | No | ||
57 | PLCD1 | 2030484 | 6601 | 0.008 | -0.0812 | No | ||
58 | APBA2BP | 5700341 | 6746 | 0.008 | -0.0887 | No | ||
59 | ATOH8 | 4540204 | 6787 | 0.008 | -0.0906 | No | ||
60 | PTPRN | 5900577 | 7257 | 0.006 | -0.1158 | No | ||
61 | AKAP1 | 110148 1740735 2260019 7000563 | 7402 | 0.005 | -0.1234 | No | ||
62 | IL9 | 3440338 | 7422 | 0.005 | -0.1242 | No | ||
63 | GJB3 | 2650040 | 7490 | 0.005 | -0.1277 | No | ||
64 | MYBPH | 2190711 | 7534 | 0.005 | -0.1298 | No | ||
65 | PRDM1 | 3170347 3520301 | 7566 | 0.005 | -0.1313 | No | ||
66 | GNAI1 | 4560390 | 7573 | 0.005 | -0.1314 | No | ||
67 | PSMA3 | 5900047 7040161 | 7576 | 0.005 | -0.1313 | No | ||
68 | TRPV3 | 540341 | 7652 | 0.005 | -0.1352 | No | ||
69 | CRYBA2 | 5900138 | 7688 | 0.005 | -0.1369 | No | ||
70 | KBTBD5 | 6350025 | 7748 | 0.004 | -0.1400 | No | ||
71 | CYP11A1 | 3450037 | 7781 | 0.004 | -0.1415 | No | ||
72 | HOXA11 | 6980133 | 7789 | 0.004 | -0.1417 | No | ||
73 | IGFBP6 | 1580181 | 7970 | 0.004 | -0.1514 | No | ||
74 | MAPRE3 | 7050504 | 7981 | 0.004 | -0.1517 | No | ||
75 | CYP24A1 | 2340338 | 8129 | 0.003 | -0.1596 | No | ||
76 | LPP | 1660541 | 8352 | 0.003 | -0.1715 | No | ||
77 | USP13 | 1450670 | 8610 | 0.002 | -0.1854 | No | ||
78 | SNCB | 3360133 | 8634 | 0.002 | -0.1866 | No | ||
79 | PAX9 | 3850519 | 8661 | 0.002 | -0.1879 | No | ||
80 | PLAC1 | 2350594 | 8667 | 0.002 | -0.1881 | No | ||
81 | EEF1A2 | 2260162 5290086 | 8692 | 0.002 | -0.1893 | No | ||
82 | IL6 | 380133 | 8741 | 0.002 | -0.1919 | No | ||
83 | EFNA1 | 3840672 | 8795 | 0.001 | -0.1947 | No | ||
84 | MAP2K1 | 840739 | 8933 | 0.001 | -0.2021 | No | ||
85 | DNM1 | 1660097 5340519 | 9130 | 0.001 | -0.2127 | No | ||
86 | ANXA7 | 6110446 | 9216 | 0.000 | -0.2173 | No | ||
87 | IL1RN | 2370333 | 9320 | 0.000 | -0.2229 | No | ||
88 | GOLGA4 | 460300 | 9534 | -0.000 | -0.2344 | No | ||
89 | EIF4G1 | 4070446 | 10028 | -0.002 | -0.2611 | No | ||
90 | VIM | 20431 | 10237 | -0.002 | -0.2723 | No | ||
91 | SLC38A3 | 5340142 | 10429 | -0.003 | -0.2826 | No | ||
92 | EIF3S1 | 6130368 6770044 | 10450 | -0.003 | -0.2835 | No | ||
93 | GAB2 | 1410280 2340520 4280040 | 10514 | -0.003 | -0.2868 | No | ||
94 | CRK | 1230162 4780128 | 10527 | -0.003 | -0.2874 | No | ||
95 | FBXW11 | 6450632 | 10645 | -0.003 | -0.2936 | No | ||
96 | UCN2 | 4590372 | 10685 | -0.004 | -0.2955 | No | ||
97 | RAD23B | 2190671 | 10914 | -0.004 | -0.3077 | No | ||
98 | PORCN | 5050519 | 10920 | -0.004 | -0.3078 | No | ||
99 | SRC | 580132 | 11095 | -0.005 | -0.3171 | No | ||
100 | ABI3 | 1740563 | 11100 | -0.005 | -0.3171 | No | ||
101 | S100A5 | 4120592 | 11145 | -0.005 | -0.3193 | No | ||
102 | MCART1 | 5270059 | 11182 | -0.005 | -0.3211 | No | ||
103 | STAT5B | 6200026 | 11303 | -0.005 | -0.3274 | No | ||
104 | FLI1 | 3990142 | 11457 | -0.006 | -0.3354 | No | ||
105 | PROSC | 380484 | 11506 | -0.006 | -0.3378 | No | ||
106 | UBQLN1 | 110280 730376 2470133 6590594 | 11703 | -0.007 | -0.3481 | No | ||
107 | OMG | 6760066 | 11988 | -0.008 | -0.3632 | No | ||
108 | NLN | 1450576 5870575 | 12126 | -0.009 | -0.3703 | No | ||
109 | HS3ST3B1 | 380040 | 12154 | -0.009 | -0.3714 | No | ||
110 | FGF11 | 840292 | 12253 | -0.009 | -0.3764 | No | ||
111 | PTPRH | 3870070 | 12292 | -0.009 | -0.3781 | No | ||
112 | GPR150 | 2570440 | 12340 | -0.010 | -0.3803 | No | ||
113 | FLNC | 2360048 5050270 | 12459 | -0.010 | -0.3863 | No | ||
114 | GABRA1 | 130372 | 12523 | -0.010 | -0.3893 | No | ||
115 | ST18 | 5720537 | 12653 | -0.011 | -0.3958 | No | ||
116 | NTRK2 | 6220463 | 12688 | -0.011 | -0.3972 | No | ||
117 | CASK | 2340215 3290576 6770215 | 12706 | -0.011 | -0.3977 | No | ||
118 | MMP7 | 1780497 | 12742 | -0.012 | -0.3991 | No | ||
119 | CMYA5 | 770528 6860075 | 12778 | -0.012 | -0.4005 | No | ||
120 | SIX4 | 6760022 | 12807 | -0.012 | -0.4016 | No | ||
121 | FGF12 | 1740446 2360037 | 12857 | -0.012 | -0.4038 | No | ||
122 | GRIN2D | 6620372 | 13030 | -0.014 | -0.4126 | No | ||
123 | IL23A | 6290044 | 13173 | -0.014 | -0.4197 | No | ||
124 | CRYGS | 2680398 | 13313 | -0.016 | -0.4266 | No | ||
125 | PSMD11 | 2340538 6510053 | 13370 | -0.016 | -0.4290 | No | ||
126 | PAPPA | 4230463 | 13716 | -0.019 | -0.4470 | No | ||
127 | TIAL1 | 4150048 6510605 | 13737 | -0.019 | -0.4473 | No | ||
128 | PAFAH1B1 | 4230333 6420121 6450066 | 13768 | -0.020 | -0.4481 | No | ||
129 | NRIP3 | 1340372 | 13782 | -0.020 | -0.4480 | No | ||
130 | MDFI | 6200041 | 13806 | -0.020 | -0.4485 | No | ||
131 | GSN | 3830168 | 13813 | -0.020 | -0.4480 | No | ||
132 | NPY | 3170138 | 13987 | -0.022 | -0.4565 | No | ||
133 | GIF | 2260056 | 14085 | -0.023 | -0.4608 | No | ||
134 | LRP1B | 1450193 | 14159 | -0.024 | -0.4638 | No | ||
135 | SGTB | 460170 | 14291 | -0.026 | -0.4699 | No | ||
136 | TLE4 | 1450064 1500519 | 14481 | -0.029 | -0.4790 | No | ||
137 | JMJD1C | 940575 2120025 | 14568 | -0.031 | -0.4824 | No | ||
138 | EPHA2 | 5890056 | 14688 | -0.033 | -0.4876 | No | ||
139 | SV2A | 1450039 5570685 | 14762 | -0.034 | -0.4902 | No | ||
140 | APOBEC1 | 4610022 | 14843 | -0.036 | -0.4931 | No | ||
141 | PTPRR | 130121 3990273 | 14884 | -0.037 | -0.4938 | No | ||
142 | FHOD1 | 2680279 | 14888 | -0.037 | -0.4924 | No | ||
143 | DUSP13 | 6400152 | 14968 | -0.039 | -0.4952 | No | ||
144 | FHL3 | 1090369 2650017 | 14980 | -0.040 | -0.4942 | No | ||
145 | SORT1 | 1850242 2320632 3870537 | 15071 | -0.042 | -0.4974 | No | ||
146 | TBC1D17 | 1780450 | 15254 | -0.047 | -0.5054 | No | ||
147 | COL27A1 | 1740390 | 15297 | -0.049 | -0.5057 | No | ||
148 | HOXD9 | 2570181 | 15429 | -0.054 | -0.5107 | No | ||
149 | BLMH | 1410438 | 15649 | -0.062 | -0.5201 | No | ||
150 | GABBR1 | 2850519 2850735 | 15686 | -0.064 | -0.5195 | No | ||
151 | UBE3A | 1240152 2690438 5860609 | 15758 | -0.067 | -0.5207 | No | ||
152 | SCOC | 610048 2230053 | 15792 | -0.069 | -0.5197 | No | ||
153 | ROM1 | 3130685 | 15857 | -0.072 | -0.5203 | No | ||
154 | STX17 | 2260037 | 15959 | -0.077 | -0.5228 | No | ||
155 | ATP6V1A | 6590242 | 15966 | -0.077 | -0.5200 | No | ||
156 | NCDN | 50040 1980739 3520603 | 16013 | -0.080 | -0.5193 | No | ||
157 | STOML2 | 1940487 | 16052 | -0.082 | -0.5181 | No | ||
158 | RGS6 | 6040601 | 16076 | -0.084 | -0.5160 | No | ||
159 | TRIP10 | 460438 | 16256 | -0.094 | -0.5220 | No | ||
160 | DCN | 510332 5340026 5900711 6550092 | 16309 | -0.098 | -0.5209 | No | ||
161 | BLVRB | 7040707 | 16312 | -0.098 | -0.5171 | No | ||
162 | CORO1C | 4570397 | 16351 | -0.101 | -0.5151 | No | ||
163 | AGPAT1 | 610056 | 16383 | -0.103 | -0.5127 | No | ||
164 | PKN3 | 2260538 | 16468 | -0.110 | -0.5129 | No | ||
165 | XLKD1 | 520441 | 16480 | -0.112 | -0.5090 | No | ||
166 | WBP5 | 7050563 | 16655 | -0.123 | -0.5135 | No | ||
167 | HCFC1 | 2260008 | 16972 | -0.154 | -0.5245 | No | ||
168 | HDAC3 | 4060072 | 17142 | -0.175 | -0.5267 | Yes | ||
169 | FIGF | 7040673 | 17178 | -0.180 | -0.5215 | Yes | ||
170 | BAZ2A | 730184 | 17253 | -0.194 | -0.5178 | Yes | ||
171 | CAPNS1 | 3940113 | 17424 | -0.225 | -0.5180 | Yes | ||
172 | AKT1S1 | 1660048 | 17572 | -0.251 | -0.5160 | Yes | ||
173 | SLC6A9 | 2470520 | 17582 | -0.254 | -0.5064 | Yes | ||
174 | UBE2C | 6130017 | 17653 | -0.271 | -0.4994 | Yes | ||
175 | LAMB3 | 7100301 | 17674 | -0.275 | -0.4896 | Yes | ||
176 | MAPK3 | 580161 4780035 | 17816 | -0.318 | -0.4846 | Yes | ||
177 | CAMKK1 | 6370324 | 17989 | -0.380 | -0.4787 | Yes | ||
178 | GNGT2 | 540176 | 17998 | -0.383 | -0.4639 | Yes | ||
179 | PPP1R9B | 3130619 | 18008 | -0.386 | -0.4490 | Yes | ||
180 | PDGFRB | 6450279 | 18091 | -0.417 | -0.4369 | Yes | ||
181 | SYTL1 | 510487 | 18131 | -0.443 | -0.4213 | Yes | ||
182 | KCNN4 | 2680129 | 18148 | -0.455 | -0.4041 | Yes | ||
183 | RAB37 | 1980725 | 18242 | -0.525 | -0.3882 | Yes | ||
184 | DTX2 | 4210041 7000008 | 18412 | -0.747 | -0.3677 | Yes | ||
185 | EEF1A1 | 1980193 1990195 4670735 | 18491 | -1.030 | -0.3309 | Yes | ||
186 | RTN4 | 50725 630647 870097 870184 | 18513 | -1.196 | -0.2844 | Yes | ||
187 | RPL23 | 2260452 4850435 6450673 | 18562 | -1.725 | -0.2183 | Yes | ||
188 | TGFBR2 | 1780711 1980537 6550398 | 18569 | -1.770 | -0.1482 | Yes | ||
189 | CIZ1 | 4150128 6130484 | 18605 | -3.785 | 0.0006 | Yes |