Details for gene set REGULATION_OF_TRANSCRIPTION__DNA

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in class	absentNotch
GeneSet	REGULATION_OF_TRANSCRIPTION__DNA_DEPENDENT
Enrichment Score (ES)	0.54469335
Normalized Enrichment Score (NES)	1.5342422
Nominal p-value	0.0
FDR q-value	0.33899945
FWER p-Value	0.991

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ARID1A	2630022 1690551 4810110	0	5.910	0.0668	Yes
2	EDF1	1660035 2640161	38	2.081	0.0883	Yes
3	KLF9	3840022	39	2.081	0.1118	Yes
4	ILF3	940722 3190647 6520110	40	2.079	0.1353	Yes
5	MDM2	3450053 5080138	41	2.078	0.1588	Yes
6	XRCC6	2850450 3870528	65	1.682	0.1765	Yes
7	UHRF1	1410273 1660242	78	1.595	0.1939	Yes
8	ATF4	730441 1740195	80	1.582	0.2117	Yes
9	ATF7IP	2690176 6770021	87	1.539	0.2288	Yes
10	HMGB1	2120670 2350044	98	1.471	0.2449	Yes
11	TNFRSF1A	1090390 6520735	100	1.464	0.2614	Yes
12	TCF12	3610324 7000156	122	1.384	0.2759	Yes
13	HDAC2	4050433	153	1.273	0.2886	Yes
14	CTCF	5340017	161	1.243	0.3023	Yes
15	BCL6	940100	181	1.170	0.3145	Yes
16	ZEB1	6840162	227	1.064	0.3240	Yes
17	ELF1	4780450	249	1.032	0.3345	Yes
18	HTATSF1	110026	266	1.005	0.3450	Yes
19	PRKAR1A	3450369	290	0.974	0.3548	Yes
20	NFATC3	5050520	346	0.910	0.3621	Yes
21	NFYB	1850053	390	0.854	0.3693	Yes
22	SMAD4	5670519	392	0.852	0.3789	Yes
23	RBAK	1770008	419	0.830	0.3869	Yes
24	SMARCC1	5080019 7100047	471	0.786	0.3930	Yes
25	MED6	6840500	478	0.778	0.4014	Yes
26	SIN3A	2190121	569	0.708	0.4045	Yes
27	TCEB1	1170619	632	0.669	0.4087	Yes
28	BRD7	2120068 6200746	639	0.664	0.4159	Yes
29	RUNX1	3840711	697	0.634	0.4199	Yes
30	LITAF	6940671	702	0.632	0.4268	Yes
31	IKBKAP	1740746 3120364	725	0.622	0.4326	Yes
32	HNRPAB	540504	740	0.612	0.4388	Yes
33	CCNH	3190347	764	0.603	0.4443	Yes
34	KLF7	50390	787	0.591	0.4498	Yes
35	DNMT1	2260097	815	0.576	0.4549	Yes
36	MNAT1	730292 2350364	823	0.572	0.4609	Yes
37	ARHGEF11	1780288	847	0.563	0.4660	Yes
38	CSDA	2470092 3060053 4780056	868	0.556	0.4712	Yes
39	MAML1	2760008	876	0.553	0.4771	Yes
40	MED12	4920095	903	0.542	0.4818	Yes
41	CREBBP	5690035 7040050	909	0.541	0.4876	Yes
42	SMARCE1	4920465 4390398	918	0.538	0.4933	Yes
43	EZH2	6130605 6380524	974	0.510	0.4960	Yes
44	E2F1	5360093	1000	0.503	0.5003	Yes
45	RB1	5900338	1014	0.497	0.5052	Yes
46	RYBP	60746	1053	0.481	0.5086	Yes
47	VEZF1	6900592	1083	0.467	0.5123	Yes
48	LIMD1	2480142	1209	0.422	0.5102	Yes
49	TFDP1	1980112	1232	0.415	0.5137	Yes
50	TCEB3	5890156	1305	0.387	0.5141	Yes
51	TCF7	3800736 5390181	1345	0.374	0.5162	Yes
52	NFYA	5860368	1359	0.372	0.5197	Yes
53	POLR2K	3870400	1360	0.372	0.5239	Yes
54	MYO6	2190332	1416	0.355	0.5249	Yes
55	ILF2	2900253	1452	0.347	0.5269	Yes
56	ING4	510632 2340619 2850176 5290706	1480	0.340	0.5293	Yes
57	TCF4	520021	1564	0.320	0.5284	Yes
58	SMAD2	4200592	1581	0.312	0.5310	Yes
59	RSF1	1580097	1591	0.309	0.5340	Yes
60	IRF2	5390044	1594	0.309	0.5374	Yes
61	SP1	6590017	1637	0.296	0.5384	Yes
62	JARID1B	4730494	1675	0.286	0.5396	Yes
63	TBX19	5270390	1768	0.264	0.5376	Yes
64	CHD1	4590048	1791	0.259	0.5393	Yes
65	GFI1	730180	1800	0.257	0.5418	Yes
66	SIRT1	1190731	1801	0.257	0.5447	Yes
67	LDB1	5270601	1854	0.244	0.5446	No
68	PHF12	870400 3130687	1944	0.222	0.5422	No
69	ARNTL	3170463	1993	0.211	0.5420	No
70	ING2	4850497	2026	0.205	0.5426	No
71	NRF1	2650195	2086	0.194	0.5415	No
72	NSD1	4560519 4780672	2092	0.193	0.5434	No
73	MECP2	1940450	2251	0.163	0.5366	No
74	PPARGC1B	3290114	2269	0.161	0.5375	No
75	RNF4	580286 1400152	2345	0.149	0.5351	No
76	STAT3	460040 3710341	2434	0.137	0.5318	No
77	ZNF148	6420403	2563	0.122	0.5262	No
78	PHF5A	2690519	2645	0.113	0.5230	No
79	BRIP1	1050427	2698	0.107	0.5214	No
80	ZHX1	2100110 2120286	2750	0.101	0.5197	No
81	CHD2	4070039	2867	0.092	0.5144	No
82	SNW1	4010736	2871	0.091	0.5153	No
83	TRAPPC2	4210301 5860601	2895	0.089	0.5151	No
84	RUVBL1	4280239 5080273	3147	0.070	0.5021	No
85	GATA4	1410215 2690609	3159	0.069	0.5023	No
86	GABPB2	6130450 7050735	3202	0.067	0.5007	No
87	SMARCD2	3830619	3225	0.065	0.5003	No
88	BRD8	1170463 2900075 4050397 6590332	3229	0.065	0.5008	No
89	ZFP161	110546 4810195	3232	0.065	0.5015	No
90	MRPL12	3120112	3303	0.060	0.4983	No
91	ATF7	2030138 4760440	3310	0.060	0.4986	No
92	BCL10	2360397	3328	0.059	0.4984	No
93	MTF1	520427 2340364	3358	0.057	0.4974	No
94	CITED2	5670114 5130088	3359	0.057	0.4981	No
95	PAWR	5130546 6330706	3379	0.056	0.4977	No
96	NRIP1	3190039	3388	0.055	0.4979	No
97	MYC	380541 4670170	3486	0.050	0.4931	No
98	KLF4	1850022 3830239 5570750	3493	0.050	0.4934	No
99	PREB	70746 3360725	3600	0.044	0.4880	No
100	TCF7L2	2190348 5220113	3759	0.037	0.4798	No
101	SOX12	1780037	3779	0.036	0.4792	No
102	ORC2L	1990470 6510019	3821	0.035	0.4773	No
103	PPARG	1990168 2680603 6130632	3831	0.034	0.4772	No
104	GATA6	1770010	3837	0.034	0.4773	No
105	TNF	6650603	3880	0.033	0.4754	No
106	EID1	6620132	3931	0.031	0.4730	No
107	JMY	3360242	3981	0.029	0.4707	No
108	ABL1	1050593 2030050 4010114	4028	0.028	0.4685	No
109	BPTF	940541 4540152	4111	0.025	0.4643	No
110	NR1D2	2360014 4540014	4147	0.024	0.4626	No
111	LRRFIP1	870259 1050204 2760377	4168	0.024	0.4618	No
112	FST	1110600	4183	0.024	0.4613	No
113	VPS4B	3440332	4205	0.023	0.4604	No
114	CREM	840156 6380438 6660041 6660168	4275	0.021	0.4569	No
115	NR6A1	4010347	4357	0.020	0.4527	No
116	STAT2	3780519	4410	0.019	0.4500	No
117	GLIS1	840471	4493	0.018	0.4458	No
118	NR0B1	6510750	4589	0.016	0.4407	No
119	FOXP3	940707 1850692	4608	0.016	0.4399	No
120	HSF4	4610273	4621	0.016	0.4395	No
121	FOXD3	6550156	4790	0.014	0.4304	No
122	SAP18	3610092	4815	0.014	0.4293	No
123	HMGB2	2640603	4887	0.013	0.4255	No
124	UBP1	6020707	4951	0.012	0.4222	No
125	SOX21	1050110 4670041 6660338	5042	0.011	0.4174	No
126	SMARCA1	4230315	5194	0.010	0.4093	No
127	SP3	3840338	5233	0.010	0.4073	No
128	RORB	6400035	5304	0.009	0.4036	No
129	NOTCH2	2570397	5426	0.009	0.3970	No
130	SNAI2	2100519	5457	0.008	0.3955	No
131	NEUROD2	5290097	5573	0.008	0.3893	No
132	ESRRG	4010181	5662	0.007	0.3846	No
133	BCOR	1660452 3940053	5863	0.007	0.3737	No
134	POU4F2	2120195 2570022	5901	0.006	0.3717	No
135	TNP1	3120048	5909	0.006	0.3714	No
136	CNBP	2570161	5932	0.006	0.3703	No
137	PAX8	5050301 5290164	6032	0.006	0.3649	No
138	NR2C2	6100097	6174	0.005	0.3573	No
139	FOXF2	1240091	6199	0.005	0.3560	No
140	DR1	5860750	6333	0.005	0.3488	No
141	FOSB	1940142	6371	0.004	0.3468	No
142	FOXE1	4810164	6444	0.004	0.3429	No
143	HNF4G	5720451	6623	0.004	0.3332	No
144	CITED1	2350670	6691	0.003	0.3296	No
145	MYF6	2690576	6722	0.003	0.3280	No
146	MKL2	5700204	6731	0.003	0.3276	No
147	ZNF35	670156	6764	0.003	0.3259	No
148	TBX5	2900132 6370484	6908	0.003	0.3181	No
149	KLF12	1660095 4810288 5340546 6520286	7161	0.002	0.3043	No
150	GLI1	4560176	7168	0.002	0.3040	No
151	PBX1	6660301	7250	0.002	0.2996	No
152	SREBF1	4780333	7392	0.001	0.2919	No
153	BMP6	2100128	7649	0.001	0.2779	No
154	CRK	1230162 4780128	7696	0.001	0.2754	No
155	TCEAL1	870577	7746	0.000	0.2727	No
156	TBX22	2100301 5670463	7788	0.000	0.2705	No
157	KLF10	4850056	7935	0.000	0.2625	No
158	BRCA1	4780669	7993	-0.000	0.2593	No
159	NR2F2	3170609 3310577	8001	-0.000	0.2590	No
160	RXRA	3800471	8027	-0.000	0.2576	No
161	SP4	3850176	8094	-0.000	0.2540	No
162	CRABP2	6940725	8120	-0.000	0.2526	No
163	REST	1500471	8229	-0.001	0.2467	No
164	TCF15	1690400	8314	-0.001	0.2421	No
165	NANOG	2230152 3140114 4730632	8323	-0.001	0.2417	No
166	TFAM	3190164 6840195	8342	-0.001	0.2407	No
167	ZFPM2	460072	8343	-0.001	0.2407	No
168	ELL3	1770484	8389	-0.001	0.2383	No
169	NFATC2	70450 540097	8399	-0.001	0.2378	No
170	YY1	6130451	8513	-0.001	0.2316	No
171	SP100	3440632	8726	-0.002	0.2201	No
172	RARB	430139 1410138	9016	-0.003	0.2043	No
173	TRERF1	6370017 6940138	9032	-0.003	0.2035	No
174	NFYC	1400746	9181	-0.003	0.1954	No
175	SMARCAL1	1450253	9279	-0.003	0.1901	No
176	KLF11	6840739	9384	-0.004	0.1845	No
177	TEAD4	1850239 6380519	9396	-0.004	0.1839	No
178	NCOA6	1780333 6450110	9535	-0.004	0.1764	No
179	EHF	4560088	9536	-0.004	0.1765	No
180	SMARCA5	6620050	9652	-0.004	0.1702	No
181	PRDM1	3170347 3520301	9655	-0.004	0.1702	No
182	HELLS	4560086 4810025	9667	-0.004	0.1696	No
183	LMX1B	1260561	9744	-0.005	0.1655	No
184	NPAS2	770670	9836	-0.005	0.1606	No
185	TIAL1	4150048 6510605	9938	-0.005	0.1551	No
186	POU6F2	5270451	10101	-0.006	0.1463	No
187	ELP4	1230576	10114	-0.006	0.1457	No
188	SP2	6400026	10163	-0.006	0.1432	No
189	NR0B2	2470692	10243	-0.006	0.1389	No
190	FOSL1	430021	10299	-0.006	0.1360	No
191	RPL6	6040735	10422	-0.007	0.1294	No
192	FOXH1	2060180	10511	-0.007	0.1246	No
193	MYOD1	1230731	10549	-0.007	0.1227	No
194	KCNIP3	6290050	10717	-0.008	0.1137	No
195	HOXC5	1580017	10743	-0.008	0.1124	No
196	TBX2	1990563	10868	-0.008	0.1057	No
197	FOXN1	4730075	10893	-0.008	0.1045	No
198	SCRT1	6760736	10966	-0.009	0.1006	No
199	CDK7	2640451	11027	-0.009	0.0974	No
200	SOX18	2320086	11053	-0.009	0.0962	No
201	PITX2	870537 2690139	11122	-0.009	0.0926	No
202	POU4F1	2260315	11314	-0.010	0.0822	No
203	NOTCH4	2450040 6370707	11342	-0.010	0.0809	No
204	TCFL5	2190019	11424	-0.011	0.0765	No
205	JMJD1C	940575 2120025	11572	-0.011	0.0686	No
206	HIF1A	5670605	11601	-0.012	0.0672	No
207	THRAP3	6180309	11717	-0.012	0.0611	No
208	HMGA2	2940121 3390647 5130279 6400136	11944	-0.014	0.0489	No
209	PHF21A	610014	12113	-0.015	0.0398	No
210	NUFIP1	6350241	12136	-0.015	0.0388	No
211	HOXD13	2260603	12149	-0.015	0.0383	No
212	BMP2	6620687	12217	-0.015	0.0348	No
213	PPARD	110131	12336	-0.017	0.0285	No
214	HIC1	2650142	12371	-0.017	0.0269	No
215	GLI2	3060632	12387	-0.017	0.0262	No
216	FOSL2	870044 1230427 6520433	12423	-0.017	0.0245	No
217	ATRX	2340039 3610132 4210373	12464	-0.018	0.0225	No
218	PTF1A	6450377	12520	-0.018	0.0197	No
219	POU2F3	2030601	12543	-0.018	0.0187	No
220	CALR	510446	12556	-0.018	0.0183	No
221	AHR	4560671	12631	-0.019	0.0144	No
222	TBX3	2570672	12640	-0.019	0.0142	No
223	MYF5	1050739	12668	-0.019	0.0129	No
224	ZBTB32	5900397	12692	-0.020	0.0119	No
225	ARID4A	520156 1050707	12707	-0.020	0.0114	No
226	SOX30	2690725 4730309	12813	-0.021	0.0059	No
227	GFI1B	4570131	12936	-0.022	-0.0006	No
228	ARID5B	110403	12946	-0.022	-0.0008	No
229	UTF1	5700593	12950	-0.022	-0.0007	No
230	MAFA	70519	13034	-0.023	-0.0050	No
231	GCM1	6510687	13038	-0.023	-0.0049	No
232	ELAVL2	360181	13069	-0.024	-0.0063	No
233	ZBTB16	3290022	13124	-0.024	-0.0090	No
234	MYST2	4540494	13230	-0.025	-0.0144	No
235	ELF2	1690014 2480132 3060180 3190504	13247	-0.026	-0.0150	No
236	IL4	6020537	13283	-0.026	-0.0166	No
237	ESR2	6220138	13307	-0.027	-0.0176	No
238	FOXO3	2510484 4480451	13380	-0.028	-0.0212	No
239	CREB5	2320368	13431	-0.028	-0.0236	No
240	MDM4	4070504 4780008	13496	-0.030	-0.0268	No
241	HDAC8	3440504	13547	-0.031	-0.0292	No
242	MLLT6	3870168	13574	-0.031	-0.0303	No
243	NME2	2190672	13654	-0.033	-0.0342	No
244	NDUFA13	6220021	13688	-0.033	-0.0356	No
245	PBX3	1300424 3710577 6180575	13801	-0.035	-0.0414	No
246	FOS	1850315	13810	-0.035	-0.0414	No
247	RPS6KA5	2120563 7040546	13819	-0.035	-0.0414	No
248	HOXC6	3850133 4920736	13874	-0.036	-0.0440	No
249	POU5F1	450739 4560605	13904	-0.037	-0.0452	No
250	ERF	110551 1770278	13929	-0.038	-0.0460	No
251	GTF2H1	2570746 2650148	14039	-0.040	-0.0516	No
252	PLAGL1	3190082 6200193	14148	-0.043	-0.0570	No
253	RNF14	50402 1340041 6370687	14225	-0.045	-0.0606	No
254	SMARCD3	4070497	14286	-0.047	-0.0634	No
255	TBX10	2690156 2640086	14309	-0.047	-0.0641	No
256	BLZF1	630088	14327	-0.048	-0.0645	No
257	POLR3C	6940546	14341	-0.048	-0.0646	No
258	TCF3	5080022	14375	-0.049	-0.0659	No
259	NARG1	5910563 6350095	14397	-0.050	-0.0665	No
260	IRF8	610161	14446	-0.051	-0.0685	No
261	SOD2	1410053	14581	-0.055	-0.0752	No
262	GCN5L2	2340609	14766	-0.061	-0.0846	No
263	NKX2-5	5390438	14777	-0.062	-0.0845	No
264	SREBF2	3390692	14798	-0.063	-0.0848	No
265	NFX1	450504	14830	-0.064	-0.0858	No
266	TBX21	5270594	14880	-0.066	-0.0878	No
267	UBN1	5900195	14899	-0.067	-0.0880	No
268	ERCC3	6900008	14917	-0.068	-0.0882	No
269	RBPJ	2360164 5550136 5720402	14993	-0.071	-0.0915	No
270	DYRK1B	5860706	15024	-0.073	-0.0923	No
271	MDFI	6200041	15168	-0.081	-0.0992	No
272	ELF4	4850193	15183	-0.082	-0.0990	No
273	ZHX2	2900452	15222	-0.084	-0.1002	No
274	ZHX3	460615	15247	-0.085	-0.1005	No
275	CLOCK	1410070 2940292 3390075	15257	-0.086	-0.1000	No
276	HCLS1	7100309	15264	-0.087	-0.0994	No
277	DRAP1	2940142	15304	-0.089	-0.1005	No
278	SIRT5	110075 2640025	15327	-0.090	-0.1007	No
279	NEUROG1	380341	15341	-0.091	-0.1004	No
280	PFDN5	460020 4230632	15352	-0.092	-0.0999	No
281	MZF1	780411 4780102 6550286	15374	-0.094	-0.1000	No
282	EPAS1	5290156	15387	-0.094	-0.0996	No
283	DBP	4200270	15413	-0.096	-0.0999	No
284	HIRA	4480609 5270167	15548	-0.108	-0.1060	No
285	HNF4A	6620440	15585	-0.111	-0.1067	No
286	GATA1	6400068	15661	-0.118	-0.1095	No
287	TADA3L	4210070 5720088 6660333	15675	-0.119	-0.1088	No
288	MYBBP1A	110592 2570435 2900711	15683	-0.120	-0.1079	No
289	TARBP2	60369 380026 4760377	15732	-0.127	-0.1090	No
290	HDAC10	2850204	15749	-0.128	-0.1085	No
291	UBTF	4210450 6840403	15790	-0.131	-0.1092	No
292	DEK	1050451 4560037	15814	-0.134	-0.1089	No
293	EPC1	1570050 5290095 6900193	15826	-0.135	-0.1080	No
294	TRIM27	3710575 4780112	15862	-0.139	-0.1084	No
295	TGFB1	1940162	15875	-0.140	-0.1074	No
296	TWIST1	5130619	15934	-0.148	-0.1089	No
297	MAP2K3	5570193	15974	-0.155	-0.1093	No
298	SPI1	1410397	15991	-0.158	-0.1084	No
299	TAF6L	1850056	16104	-0.171	-0.1126	No
300	PA2G4	2030463	16206	-0.185	-0.1160	No
301	TRIM28	380292	16232	-0.189	-0.1153	No
302	DDIT3	780373	16274	-0.194	-0.1153	No
303	ZMYND11	630181 2570019 4850138 5360040	16370	-0.211	-0.1181	No
304	NR5A1	70707	16380	-0.212	-0.1162	No
305	CXXC1	630170 3940136	16409	-0.216	-0.1153	No
306	TCF19	6200152	16518	-0.230	-0.1187	No
307	HSBP1	6900687	16658	-0.249	-0.1234	No
308	MXD4	4810113	16709	-0.257	-0.1233	No
309	VPS72	2450181	16728	-0.260	-0.1213	No
310	RBM14	5340731 5690315	16739	-0.262	-0.1189	No
311	ELP3	3440438	16825	-0.277	-0.1204	No
312	IRF7	1570605	16875	-0.286	-0.1199	No
313	JUNB	4230048	16903	-0.291	-0.1181	No
314	NFE2	3710373	16956	-0.301	-0.1175	No
315	SUPT5H	4150546	16987	-0.306	-0.1157	No
316	SUPT4H1	6200056	17021	-0.312	-0.1140	No
317	HTATIP2	3120465	17045	-0.318	-0.1116	No
318	SQSTM1	6550056	17055	-0.319	-0.1085	No
319	DAXX	4010647	17183	-0.346	-0.1116	No
320	NFKB2	2320670	17210	-0.350	-0.1090	No
321	SCAP	3800706	17258	-0.361	-0.1075	No
322	ATF5	5670685	17284	-0.368	-0.1047	No
323	PBX4	6370086	17353	-0.384	-0.1041	No
324	RPS6KA4	2190524	17372	-0.388	-0.1007	No
325	ARID5A	2450133	17414	-0.400	-0.0985	No
326	PQBP1	6520603	17446	-0.409	-0.0955	No
327	SUFU	6650181	17447	-0.409	-0.0909	No
328	UBE2V1	2470093	17454	-0.412	-0.0866	No
329	CHD4	5420059 6130338 6380717	17466	-0.415	-0.0825	No
330	SMAD3	6450671	17586	-0.454	-0.0839	No
331	ABCA2	5050039	17687	-0.486	-0.0839	No
332	TP53	6130707	17702	-0.490	-0.0791	No
333	ZNF76	3850020	17708	-0.492	-0.0738	No
334	CHMP1A	5550441	17782	-0.523	-0.0719	No
335	CARM1	7040292	17787	-0.527	-0.0661	No
336	SMARCD1	3060193 3850184 6400369	17805	-0.536	-0.0610	No
337	SUPT3H	6650139	17915	-0.594	-0.0603	No
338	ERCC2	2360750 4060390 6550138	17996	-0.639	-0.0574	No
339	TWIST2	6760433	18015	-0.652	-0.0510	No
340	E2F6	3120133 3850332 4070324	18046	-0.680	-0.0450	No
341	SMARCB1	5860494	18105	-0.742	-0.0398	No
342	HMGA1	6580408	18109	-0.743	-0.0315	No
343	MEN1	4850300 5900671	18216	-0.852	-0.0277	No
344	NFATC1	510400 2320348 4050600 6180161 6290136 6620086	18267	-0.926	-0.0200	No
345	PEX14	520603	18274	-0.929	-0.0098	No
346	HDAC5	2370035 6370139	18289	-0.948	0.0001	No
347	ENO1	5340128	18494	-1.566	0.0067	No