Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | UVC_HIGH_ALL_DN |
Enrichment Score (ES) | 0.636486 |
Normalized Enrichment Score (NES) | 1.7219206 |
Nominal p-value | 0.0 |
FDR q-value | 0.023529101 |
FWER p-Value | 0.113 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | KLF9 | 3840022 | 39 | 2.081 | 0.0338 | Yes | ||
2 | EMP1 | 4120438 | 60 | 1.755 | 0.0630 | Yes | ||
3 | RBM5 | 3520402 5270121 | 76 | 1.603 | 0.0899 | Yes | ||
4 | LBR | 4540671 | 95 | 1.478 | 0.1145 | Yes | ||
5 | TNFRSF1A | 1090390 6520735 | 100 | 1.464 | 0.1395 | Yes | ||
6 | SEC24B | 460717 3060040 | 111 | 1.415 | 0.1634 | Yes | ||
7 | ATP2A2 | 1090075 3990279 | 134 | 1.356 | 0.1857 | Yes | ||
8 | PTK2 | 1780148 | 136 | 1.342 | 0.2088 | Yes | ||
9 | TLK1 | 7100605 | 222 | 1.071 | 0.2227 | Yes | ||
10 | SPOP | 450035 | 232 | 1.060 | 0.2405 | Yes | ||
11 | NASP | 2260139 2940369 5130707 | 245 | 1.040 | 0.2578 | Yes | ||
12 | RAB14 | 6860139 | 260 | 1.015 | 0.2746 | Yes | ||
13 | MAPK6 | 6760520 | 376 | 0.875 | 0.2834 | Yes | ||
14 | NFYB | 1850053 | 390 | 0.854 | 0.2975 | Yes | ||
15 | UBE2G1 | 2230546 5420528 7040463 | 393 | 0.851 | 0.3120 | Yes | ||
16 | CDC6 | 4570296 5360600 | 400 | 0.848 | 0.3264 | Yes | ||
17 | MARCKS | 7040450 | 438 | 0.816 | 0.3384 | Yes | ||
18 | PITPNB | 5130039 | 451 | 0.802 | 0.3516 | Yes | ||
19 | GTF2E1 | 4070014 | 464 | 0.796 | 0.3647 | Yes | ||
20 | THUMPD1 | 7510148 | 473 | 0.786 | 0.3779 | Yes | ||
21 | CDR2 | 6200377 | 477 | 0.778 | 0.3911 | Yes | ||
22 | DDX3X | 2190020 | 518 | 0.751 | 0.4019 | Yes | ||
23 | RARS | 380390 | 554 | 0.719 | 0.4125 | Yes | ||
24 | BMI1 | 3830026 2630204 | 621 | 0.678 | 0.4206 | Yes | ||
25 | TOP2A | 360717 | 627 | 0.675 | 0.4320 | Yes | ||
26 | MPHOSPH6 | 5570164 | 629 | 0.674 | 0.4436 | Yes | ||
27 | RHOB | 1500309 | 651 | 0.657 | 0.4538 | Yes | ||
28 | KPNA2 | 3450114 | 672 | 0.648 | 0.4639 | Yes | ||
29 | RUNX1 | 3840711 | 697 | 0.634 | 0.4735 | Yes | ||
30 | STX7 | 5910484 | 719 | 0.625 | 0.4832 | Yes | ||
31 | RAF1 | 1770600 | 732 | 0.615 | 0.4932 | Yes | ||
32 | ADM | 4810121 | 775 | 0.597 | 0.5012 | Yes | ||
33 | RAB1A | 2370671 | 791 | 0.589 | 0.5105 | Yes | ||
34 | TNFAIP8 | 2760551 | 884 | 0.549 | 0.5150 | Yes | ||
35 | KIF23 | 5570112 | 915 | 0.539 | 0.5227 | Yes | ||
36 | ZBED4 | 770441 | 1025 | 0.493 | 0.5253 | Yes | ||
37 | TNFAIP3 | 2900142 | 1033 | 0.490 | 0.5334 | Yes | ||
38 | RYBP | 60746 | 1053 | 0.481 | 0.5406 | Yes | ||
39 | CRKL | 4050427 | 1094 | 0.462 | 0.5464 | Yes | ||
40 | PHTF2 | 6590053 | 1107 | 0.458 | 0.5537 | Yes | ||
41 | UGCG | 3420053 | 1126 | 0.452 | 0.5605 | Yes | ||
42 | PRKCD | 770592 | 1137 | 0.447 | 0.5677 | Yes | ||
43 | TBL1X | 6400524 | 1159 | 0.441 | 0.5742 | Yes | ||
44 | CBX3 | 1780592 3940008 | 1257 | 0.405 | 0.5759 | Yes | ||
45 | CUL1 | 1990632 | 1308 | 0.386 | 0.5799 | Yes | ||
46 | SFRS3 | 770315 4230593 | 1323 | 0.381 | 0.5857 | Yes | ||
47 | TAF11 | 5720538 | 1409 | 0.357 | 0.5872 | Yes | ||
48 | MAPK14 | 5290731 | 1417 | 0.354 | 0.5930 | Yes | ||
49 | SLC20A2 | 5700577 | 1547 | 0.325 | 0.5916 | Yes | ||
50 | TLK2 | 1170161 | 1577 | 0.313 | 0.5954 | Yes | ||
51 | BHLHB2 | 7040603 | 1656 | 0.290 | 0.5962 | Yes | ||
52 | SNX4 | 1980358 | 1663 | 0.290 | 0.6008 | Yes | ||
53 | HMGCR | 2630242 | 1668 | 0.289 | 0.6056 | Yes | ||
54 | TLE1 | 540390 1580309 3710019 | 1734 | 0.272 | 0.6068 | Yes | ||
55 | EMG1 | 50286 380242 | 1740 | 0.270 | 0.6112 | Yes | ||
56 | DUSP11 | 1500088 4610280 | 1769 | 0.264 | 0.6142 | Yes | ||
57 | AURKA | 780537 | 1786 | 0.261 | 0.6179 | Yes | ||
58 | CHD1 | 4590048 | 1791 | 0.259 | 0.6221 | Yes | ||
59 | DICER1 | 540286 | 1808 | 0.255 | 0.6257 | Yes | ||
60 | FUS | 4760619 | 1859 | 0.242 | 0.6271 | Yes | ||
61 | TPST1 | 2570358 | 1863 | 0.242 | 0.6311 | Yes | ||
62 | BLCAP | 3990253 | 1889 | 0.235 | 0.6338 | Yes | ||
63 | MAT2A | 4070026 4730079 6020280 | 1915 | 0.232 | 0.6365 | Yes | ||
64 | RIPK1 | 3190025 | 2067 | 0.197 | 0.6317 | No | ||
65 | ATP6V1B2 | 4060528 | 2090 | 0.193 | 0.6338 | No | ||
66 | CASP8 | 4850154 | 2253 | 0.162 | 0.6278 | No | ||
67 | REV3L | 1090717 | 2266 | 0.161 | 0.6299 | No | ||
68 | ARL4C | 1190279 | 2317 | 0.154 | 0.6299 | No | ||
69 | RNF4 | 580286 1400152 | 2345 | 0.149 | 0.6310 | No | ||
70 | RAD21 | 1990278 | 2400 | 0.143 | 0.6305 | No | ||
71 | SQLE | 50180 940092 | 2525 | 0.125 | 0.6259 | No | ||
72 | COIL | 4480408 | 2557 | 0.122 | 0.6264 | No | ||
73 | NCOA3 | 4540195 | 2576 | 0.121 | 0.6275 | No | ||
74 | DYRK1A | 3190181 | 2635 | 0.115 | 0.6263 | No | ||
75 | PPP1R12A | 4070066 4590162 | 2650 | 0.113 | 0.6275 | No | ||
76 | PDCD10 | 4760500 | 2701 | 0.107 | 0.6266 | No | ||
77 | CASP3 | 6620397 | 2706 | 0.106 | 0.6282 | No | ||
78 | STX3 | 1190563 2640215 | 2793 | 0.098 | 0.6252 | No | ||
79 | SMURF2 | 1940161 | 2846 | 0.093 | 0.6240 | No | ||
80 | RAB11A | 5360079 | 2877 | 0.091 | 0.6240 | No | ||
81 | NTF3 | 5890131 | 3071 | 0.075 | 0.6148 | No | ||
82 | ACVR1B | 3610446 5570195 | 3139 | 0.071 | 0.6123 | No | ||
83 | BACH1 | 290195 | 3157 | 0.070 | 0.6126 | No | ||
84 | IL4R | 2370520 | 3163 | 0.069 | 0.6135 | No | ||
85 | STRN3 | 1450093 6200685 | 3177 | 0.068 | 0.6140 | No | ||
86 | CCNA2 | 5290075 | 3209 | 0.066 | 0.6135 | No | ||
87 | NFE2L2 | 2810619 3390162 | 3228 | 0.065 | 0.6136 | No | ||
88 | BRD8 | 1170463 2900075 4050397 6590332 | 3229 | 0.065 | 0.6147 | No | ||
89 | DUSP1 | 6860121 | 3287 | 0.061 | 0.6127 | No | ||
90 | GBAS | 6760278 | 3352 | 0.057 | 0.6102 | No | ||
91 | CITED2 | 5670114 5130088 | 3359 | 0.057 | 0.6108 | No | ||
92 | NRIP1 | 3190039 | 3388 | 0.055 | 0.6103 | No | ||
93 | E2F3 | 50162 460180 | 3439 | 0.052 | 0.6085 | No | ||
94 | BMPR1A | 2190193 4060603 | 3492 | 0.050 | 0.6065 | No | ||
95 | KRIT1 | 2640500 4230435 4730184 | 3513 | 0.049 | 0.6063 | No | ||
96 | WEE1 | 3390070 | 3537 | 0.047 | 0.6058 | No | ||
97 | CSTF3 | 3850156 5570458 | 3618 | 0.044 | 0.6022 | No | ||
98 | EIF4E | 1580403 70133 6380215 | 3698 | 0.039 | 0.5986 | No | ||
99 | PDGFRA | 2940332 | 3792 | 0.036 | 0.5942 | No | ||
100 | CCNG1 | 870402 1500685 6110594 | 3939 | 0.031 | 0.5868 | No | ||
101 | AMD1 | 6290128 | 4016 | 0.028 | 0.5831 | No | ||
102 | ITGA6 | 3830129 | 4052 | 0.027 | 0.5817 | No | ||
103 | STK24 | 6760484 | 4137 | 0.025 | 0.5776 | No | ||
104 | PIP5K3 | 5360112 | 4356 | 0.020 | 0.5660 | No | ||
105 | MET | 2690348 | 4529 | 0.017 | 0.5570 | No | ||
106 | TOPBP1 | 6020333 | 4640 | 0.016 | 0.5513 | No | ||
107 | STAM | 3850008 4760441 | 4649 | 0.016 | 0.5511 | No | ||
108 | FYN | 2100468 4760520 4850687 | 4821 | 0.014 | 0.5420 | No | ||
109 | PFTK1 | 1780181 | 4880 | 0.013 | 0.5391 | No | ||
110 | HMGB2 | 2640603 | 4887 | 0.013 | 0.5390 | No | ||
111 | SSH1 | 7000538 | 4967 | 0.012 | 0.5349 | No | ||
112 | IDI1 | 1450736 | 4989 | 0.012 | 0.5340 | No | ||
113 | GNAI1 | 4560390 | 5244 | 0.010 | 0.5203 | No | ||
114 | STXBP3 | 780706 | 5333 | 0.009 | 0.5157 | No | ||
115 | PODXL | 130717 | 5399 | 0.009 | 0.5123 | No | ||
116 | TM4SF1 | 2570021 | 5913 | 0.006 | 0.4845 | No | ||
117 | TSPAN5 | 6770019 | 5964 | 0.006 | 0.4819 | No | ||
118 | FGF5 | 5270204 | 5968 | 0.006 | 0.4819 | No | ||
119 | EDG2 | 6290215 | 6071 | 0.006 | 0.4764 | No | ||
120 | RND3 | 940504 | 6119 | 0.005 | 0.4740 | No | ||
121 | DR1 | 5860750 | 6333 | 0.005 | 0.4625 | No | ||
122 | ZFAND5 | 6770673 | 6353 | 0.005 | 0.4615 | No | ||
123 | FHL5 | 430400 | 6455 | 0.004 | 0.4561 | No | ||
124 | SCHIP1 | 4560152 | 6563 | 0.004 | 0.4503 | No | ||
125 | TIPARP | 50397 | 6570 | 0.004 | 0.4501 | No | ||
126 | GATA2 | 6590280 | 6661 | 0.004 | 0.4452 | No | ||
127 | GEM | 5290082 | 6891 | 0.003 | 0.4328 | No | ||
128 | VEGFC | 5910494 | 6925 | 0.003 | 0.4311 | No | ||
129 | SLBP | 6220601 | 7017 | 0.002 | 0.4262 | No | ||
130 | MFAP1 | 6660092 | 7281 | 0.002 | 0.4119 | No | ||
131 | TLE4 | 1450064 1500519 | 7327 | 0.002 | 0.4095 | No | ||
132 | ARHGEF7 | 1690441 | 7399 | 0.001 | 0.4057 | No | ||
133 | XPO1 | 540707 | 7497 | 0.001 | 0.4004 | No | ||
134 | PLEKHC1 | 2650066 | 7623 | 0.001 | 0.3936 | No | ||
135 | SERTAD2 | 2810673 6840450 | 7660 | 0.001 | 0.3917 | No | ||
136 | PUM2 | 4200441 5910446 | 7695 | 0.001 | 0.3898 | No | ||
137 | PNN | 6650504 | 7833 | 0.000 | 0.3824 | No | ||
138 | RRS1 | 4560551 | 7842 | 0.000 | 0.3820 | No | ||
139 | NR2F2 | 3170609 3310577 | 8001 | -0.000 | 0.3734 | No | ||
140 | PDE4B | 4480121 | 8121 | -0.000 | 0.3669 | No | ||
141 | NUP153 | 7000452 | 8185 | -0.001 | 0.3635 | No | ||
142 | GAS1 | 2120504 | 8332 | -0.001 | 0.3556 | No | ||
143 | CKS2 | 1410156 | 8350 | -0.001 | 0.3547 | No | ||
144 | SAMD4A | 1170717 | 8355 | -0.001 | 0.3545 | No | ||
145 | YY1 | 6130451 | 8513 | -0.001 | 0.3460 | No | ||
146 | SATB2 | 2470181 | 8753 | -0.002 | 0.3330 | No | ||
147 | EPS8 | 7050204 | 8774 | -0.002 | 0.3320 | No | ||
148 | CTGF | 4540577 | 9135 | -0.003 | 0.3124 | No | ||
149 | IRS1 | 1190204 | 9285 | -0.003 | 0.3044 | No | ||
150 | SMAD7 | 430377 | 9309 | -0.003 | 0.3032 | No | ||
151 | STK38 | 7100114 | 9573 | -0.004 | 0.2890 | No | ||
152 | SS18 | 1940440 2900072 6900129 | 9619 | -0.004 | 0.2866 | No | ||
153 | POGZ | 870348 7040286 | 9825 | -0.005 | 0.2755 | No | ||
154 | POLE2 | 6110041 | 9910 | -0.005 | 0.2711 | No | ||
155 | GREM1 | 3940180 | 10157 | -0.006 | 0.2578 | No | ||
156 | BNIP2 | 1410475 6770088 | 10503 | -0.007 | 0.2392 | No | ||
157 | CDK7 | 2640451 | 11027 | -0.009 | 0.2109 | No | ||
158 | CNOT2 | 520546 2060397 4610543 5550113 | 11190 | -0.010 | 0.2022 | No | ||
159 | AGTR1 | 4780524 2680592 | 11345 | -0.010 | 0.1940 | No | ||
160 | MLX | 1770450 7040452 | 11581 | -0.012 | 0.1815 | No | ||
161 | CTDSP2 | 5340315 5690133 | 11641 | -0.012 | 0.1785 | No | ||
162 | ZFP36L2 | 510180 | 11931 | -0.014 | 0.1630 | No | ||
163 | HMGA2 | 2940121 3390647 5130279 6400136 | 11944 | -0.014 | 0.1626 | No | ||
164 | THBS1 | 4560494 430288 | 12093 | -0.015 | 0.1548 | No | ||
165 | NCK1 | 6200575 6510050 | 12145 | -0.015 | 0.1522 | No | ||
166 | BCAR3 | 1660717 | 12186 | -0.015 | 0.1503 | No | ||
167 | FOSL2 | 870044 1230427 6520433 | 12423 | -0.017 | 0.1378 | No | ||
168 | PKP4 | 3710400 5890097 | 12452 | -0.017 | 0.1366 | No | ||
169 | KIF2A | 3990286 6130575 | 12485 | -0.018 | 0.1351 | No | ||
170 | CXCL12 | 580546 4150750 4570068 | 12619 | -0.019 | 0.1282 | No | ||
171 | FZD7 | 7050706 | 12744 | -0.020 | 0.1218 | No | ||
172 | CYR61 | 1240408 5290026 4120452 6550008 | 12783 | -0.021 | 0.1201 | No | ||
173 | DLX2 | 2320438 4200673 | 12854 | -0.021 | 0.1167 | No | ||
174 | TUBGCP3 | 4920563 | 12884 | -0.022 | 0.1155 | No | ||
175 | ARID5B | 110403 | 12946 | -0.022 | 0.1126 | No | ||
176 | TRIM32 | 4150332 | 13036 | -0.023 | 0.1081 | No | ||
177 | CD2AP | 1940369 | 13073 | -0.024 | 0.1066 | No | ||
178 | SPRED2 | 510138 540195 | 13499 | -0.030 | 0.0840 | No | ||
179 | PAFAH1B1 | 4230333 6420121 6450066 | 13599 | -0.032 | 0.0791 | No | ||
180 | PPP2R5C | 3310121 6650672 | 13814 | -0.035 | 0.0681 | No | ||
181 | SPEN | 2060041 | 13840 | -0.036 | 0.0674 | No | ||
182 | UAP1 | 3060093 | 13857 | -0.036 | 0.0671 | No | ||
183 | CEBPD | 3360176 | 13966 | -0.038 | 0.0619 | No | ||
184 | HDHD1A | 6220328 | 14137 | -0.042 | 0.0534 | No | ||
185 | USP1 | 2760541 5690438 6220673 | 14219 | -0.045 | 0.0498 | No | ||
186 | HOXB2 | 6450592 | 14288 | -0.047 | 0.0469 | No | ||
187 | PPAP2B | 3190397 4730280 | 14423 | -0.050 | 0.0405 | No | ||
188 | RRAS2 | 6290170 | 14449 | -0.051 | 0.0400 | No | ||
189 | FADD | 2360593 4210692 6520019 | 14672 | -0.058 | 0.0289 | No | ||
190 | CENPA | 5080154 | 14675 | -0.058 | 0.0298 | No | ||
191 | CDYL | 4200142 4730397 6060400 | 14759 | -0.061 | 0.0264 | No | ||
192 | SWAP70 | 2810577 2850739 5130594 | 14943 | -0.069 | 0.0176 | No | ||
193 | PLK4 | 430162 5720110 | 15052 | -0.075 | 0.0130 | No | ||
194 | CDK8 | 1050113 1190601 1780358 6110102 | 15161 | -0.081 | 0.0086 | No | ||
195 | ELF4 | 4850193 | 15183 | -0.082 | 0.0088 | No | ||
196 | UBE2N | 520369 2900047 | 15209 | -0.083 | 0.0089 | No | ||
197 | ZHX3 | 460615 | 15247 | -0.085 | 0.0084 | No | ||
198 | DDIT4 | 2570408 | 15400 | -0.095 | 0.0017 | No | ||
199 | SIAH2 | 7210672 | 15454 | -0.099 | 0.0006 | No | ||
200 | HAS2 | 5360181 | 15502 | -0.103 | -0.0002 | No | ||
201 | SRF | 70139 2320039 | 15671 | -0.119 | -0.0073 | No | ||
202 | TRIB2 | 4120605 | 15788 | -0.131 | -0.0113 | No | ||
203 | UBTF | 4210450 6840403 | 15790 | -0.131 | -0.0091 | No | ||
204 | FBXO46 | 870273 | 15853 | -0.138 | -0.0101 | No | ||
205 | TWIST1 | 5130619 | 15934 | -0.148 | -0.0119 | No | ||
206 | HERPUD1 | 7100440 | 15995 | -0.158 | -0.0124 | No | ||
207 | NFIL3 | 4070377 | 16035 | -0.163 | -0.0117 | No | ||
208 | FZD2 | 6480154 | 16082 | -0.169 | -0.0113 | No | ||
209 | TRIP10 | 460438 | 16275 | -0.194 | -0.0184 | No | ||
210 | ARF6 | 3520026 | 16291 | -0.197 | -0.0158 | No | ||
211 | PMP22 | 4010239 6550072 | 16723 | -0.259 | -0.0348 | No | ||
212 | USP10 | 2030736 2450333 | 16785 | -0.271 | -0.0334 | No | ||
213 | GNE | 6100465 | 16842 | -0.280 | -0.0316 | No | ||
214 | LHFPL2 | 450020 | 17005 | -0.310 | -0.0351 | No | ||
215 | PTPN1 | 2650056 | 17049 | -0.318 | -0.0319 | No | ||
216 | UNG | 3130110 6100364 | 17559 | -0.441 | -0.0520 | No | ||
217 | SMAD3 | 6450671 | 17586 | -0.454 | -0.0456 | No | ||
218 | LSM2 | 510082 | 17646 | -0.473 | -0.0406 | No | ||
219 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 17691 | -0.487 | -0.0346 | No | ||
220 | TARDBP | 870390 2350093 | 17715 | -0.494 | -0.0273 | No | ||
221 | MTMR3 | 1050014 4920180 | 17716 | -0.495 | -0.0188 | No | ||
222 | PHC2 | 1430433 | 17886 | -0.577 | -0.0180 | No | ||
223 | IFNGR2 | 1500288 2100176 | 18064 | -0.699 | -0.0155 | No | ||
224 | PARP1 | 4780446 6400338 | 18279 | -0.938 | -0.0109 | No | ||
225 | IGF2BP3 | 2810161 4230338 | 18515 | -1.691 | 0.0055 | No |