Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | ET743_SARCOMA_DN |
Enrichment Score (ES) | 0.6203419 |
Normalized Enrichment Score (NES) | 1.6485517 |
Nominal p-value | 0.0 |
FDR q-value | 0.074975714 |
FWER p-Value | 0.559 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BTG1 | 4200735 6040131 6200133 | 14 | 2.662 | 0.0487 | Yes | ||
2 | SIRPA | 130465 5700332 | 54 | 1.848 | 0.0810 | Yes | ||
3 | LBR | 4540671 | 95 | 1.478 | 0.1063 | Yes | ||
4 | HSPH1 | 1690017 | 121 | 1.386 | 0.1307 | Yes | ||
5 | CDC5L | 3130446 3390025 6400204 | 125 | 1.376 | 0.1561 | Yes | ||
6 | PRKACB | 4210170 | 131 | 1.364 | 0.1812 | Yes | ||
7 | HDAC2 | 4050433 | 153 | 1.273 | 0.2037 | Yes | ||
8 | RAP1B | 3710138 | 192 | 1.148 | 0.2230 | Yes | ||
9 | TBK1 | 5690338 | 223 | 1.069 | 0.2412 | Yes | ||
10 | DCK | 6900411 | 231 | 1.060 | 0.2606 | Yes | ||
11 | EP400 | 3940722 | 285 | 0.983 | 0.2760 | Yes | ||
12 | GTF2H2 | 5130358 | 305 | 0.954 | 0.2927 | Yes | ||
13 | DDX21 | 6100446 | 309 | 0.946 | 0.3101 | Yes | ||
14 | RPP14 | 7040014 | 345 | 0.911 | 0.3251 | Yes | ||
15 | SLC4A1AP | 3190576 | 354 | 0.901 | 0.3414 | Yes | ||
16 | RABGAP1 | 5050397 | 368 | 0.884 | 0.3572 | Yes | ||
17 | RABGGTB | 3120037 | 428 | 0.823 | 0.3693 | Yes | ||
18 | SRPK2 | 6380341 | 440 | 0.812 | 0.3838 | Yes | ||
19 | TMPO | 4050494 | 450 | 0.804 | 0.3982 | Yes | ||
20 | PSMA4 | 4560427 | 485 | 0.771 | 0.4107 | Yes | ||
21 | CCT4 | 6380161 | 506 | 0.758 | 0.4237 | Yes | ||
22 | DDX20 | 3290348 | 552 | 0.721 | 0.4347 | Yes | ||
23 | TOP2A | 360717 | 627 | 0.675 | 0.4432 | Yes | ||
24 | UBE2D2 | 4590671 6510446 | 656 | 0.656 | 0.4539 | Yes | ||
25 | OSBPL9 | 2570373 | 683 | 0.641 | 0.4644 | Yes | ||
26 | FAF1 | 2450717 2510121 4730156 | 706 | 0.630 | 0.4749 | Yes | ||
27 | POLD3 | 6400278 | 722 | 0.624 | 0.4857 | Yes | ||
28 | PSMD14 | 5690593 | 743 | 0.611 | 0.4960 | Yes | ||
29 | CCNH | 3190347 | 764 | 0.603 | 0.5061 | Yes | ||
30 | RAB1A | 2370671 | 791 | 0.589 | 0.5156 | Yes | ||
31 | PPP2R5E | 70671 2120056 | 801 | 0.583 | 0.5260 | Yes | ||
32 | PCNA | 940754 | 833 | 0.569 | 0.5349 | Yes | ||
33 | SLC25A17 | 2100369 | 941 | 0.525 | 0.5388 | Yes | ||
34 | AOF2 | 2060300 | 985 | 0.506 | 0.5459 | Yes | ||
35 | MCTS1 | 6130133 | 1100 | 0.460 | 0.5482 | Yes | ||
36 | SFRS3 | 770315 4230593 | 1323 | 0.381 | 0.5433 | Yes | ||
37 | MAP3K7 | 6040068 | 1368 | 0.370 | 0.5478 | Yes | ||
38 | EIF4B | 5390563 5270577 | 1372 | 0.369 | 0.5545 | Yes | ||
39 | MAPK14 | 5290731 | 1417 | 0.354 | 0.5587 | Yes | ||
40 | OGT | 2360131 4610333 | 1440 | 0.350 | 0.5640 | Yes | ||
41 | ZDHHC5 | 1690711 | 1557 | 0.322 | 0.5636 | Yes | ||
42 | CRLF3 | 6620019 | 1593 | 0.309 | 0.5675 | Yes | ||
43 | FNTA | 70059 | 1609 | 0.303 | 0.5723 | Yes | ||
44 | BCL2L1 | 1580452 4200152 5420484 | 1636 | 0.296 | 0.5764 | Yes | ||
45 | UBE2D3 | 3190452 | 1699 | 0.280 | 0.5782 | Yes | ||
46 | STAU1 | 2320494 | 1736 | 0.271 | 0.5813 | Yes | ||
47 | RBM17 | 870592 | 1758 | 0.267 | 0.5852 | Yes | ||
48 | AURKA | 780537 | 1786 | 0.261 | 0.5885 | Yes | ||
49 | SIRT1 | 1190731 | 1801 | 0.257 | 0.5926 | Yes | ||
50 | NET1 | 2900707 | 1824 | 0.252 | 0.5960 | Yes | ||
51 | USP3 | 2060332 | 1862 | 0.242 | 0.5985 | Yes | ||
52 | MAT2A | 4070026 4730079 6020280 | 1915 | 0.232 | 0.6000 | Yes | ||
53 | TXNRD1 | 6590446 | 1920 | 0.230 | 0.6041 | Yes | ||
54 | PRIM2A | 7000692 | 1931 | 0.226 | 0.6077 | Yes | ||
55 | PJA2 | 430537 | 2020 | 0.206 | 0.6068 | Yes | ||
56 | RIPK1 | 3190025 | 2067 | 0.197 | 0.6079 | Yes | ||
57 | MRPL15 | 360390 | 2114 | 0.189 | 0.6090 | Yes | ||
58 | SUPV3L1 | 1170072 | 2124 | 0.187 | 0.6119 | Yes | ||
59 | TNFSF5IP1 | 2060095 | 2148 | 0.182 | 0.6141 | Yes | ||
60 | PSME3 | 2810537 | 2159 | 0.180 | 0.6169 | Yes | ||
61 | PPP1CC | 6380300 2510647 | 2165 | 0.179 | 0.6199 | Yes | ||
62 | ELOVL6 | 5340746 | 2267 | 0.161 | 0.6175 | Yes | ||
63 | CDK5R1 | 3870161 | 2270 | 0.161 | 0.6203 | Yes | ||
64 | XBP1 | 3840594 | 2353 | 0.148 | 0.6186 | No | ||
65 | YWHAE | 5310435 | 2426 | 0.138 | 0.6173 | No | ||
66 | GTF2B | 6860685 | 2553 | 0.122 | 0.6127 | No | ||
67 | PSMC6 | 2810021 | 2614 | 0.117 | 0.6116 | No | ||
68 | MCM3 | 5570068 | 2691 | 0.107 | 0.6095 | No | ||
69 | TCERG1 | 2350551 4540397 5220746 | 2854 | 0.092 | 0.6024 | No | ||
70 | CLCN7 | 2970095 | 2959 | 0.083 | 0.5983 | No | ||
71 | BIRC2 | 2940435 4730020 | 3059 | 0.076 | 0.5944 | No | ||
72 | STK17B | 130091 | 3191 | 0.067 | 0.5885 | No | ||
73 | GABPB2 | 6130450 7050735 | 3202 | 0.067 | 0.5892 | No | ||
74 | CCNA2 | 5290075 | 3209 | 0.066 | 0.5901 | No | ||
75 | SRRM2 | 2940746 6350253 | 3241 | 0.064 | 0.5896 | No | ||
76 | EML4 | 5700373 | 3329 | 0.058 | 0.5860 | No | ||
77 | FBXL3 | 5910142 | 3383 | 0.056 | 0.5841 | No | ||
78 | MYC | 380541 4670170 | 3486 | 0.050 | 0.5795 | No | ||
79 | WEE1 | 3390070 | 3537 | 0.047 | 0.5777 | No | ||
80 | USP12 | 6130735 6620280 | 3562 | 0.046 | 0.5773 | No | ||
81 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 3665 | 0.041 | 0.5725 | No | ||
82 | ARFGEF2 | 5550500 | 3711 | 0.039 | 0.5708 | No | ||
83 | FNDC3A | 2690097 3290044 | 3726 | 0.038 | 0.5707 | No | ||
84 | LUZP1 | 940075 4280458 6180070 | 3912 | 0.032 | 0.5613 | No | ||
85 | MRPS35 | 2370603 4070551 | 3933 | 0.031 | 0.5608 | No | ||
86 | PSMB1 | 2940402 | 4007 | 0.028 | 0.5573 | No | ||
87 | CDC23 | 3190593 | 4029 | 0.028 | 0.5567 | No | ||
88 | PAFAH2 | 3140451 5720593 6510014 | 4302 | 0.021 | 0.5423 | No | ||
89 | RCOR1 | 5360717 | 4359 | 0.020 | 0.5397 | No | ||
90 | PTPRK | 1450433 2640142 | 4623 | 0.016 | 0.5257 | No | ||
91 | SSFA2 | 3870133 | 4809 | 0.014 | 0.5159 | No | ||
92 | FYN | 2100468 4760520 4850687 | 4821 | 0.014 | 0.5155 | No | ||
93 | HSPA1L | 4010538 | 4869 | 0.013 | 0.5132 | No | ||
94 | GGPS1 | 840128 2320215 | 5005 | 0.012 | 0.5061 | No | ||
95 | ACSL3 | 3140195 | 5118 | 0.011 | 0.5002 | No | ||
96 | RAD23B | 2190671 | 5251 | 0.010 | 0.4933 | No | ||
97 | GOPC | 6620400 | 5384 | 0.009 | 0.4863 | No | ||
98 | CDC42BPA | 840671 | 5675 | 0.007 | 0.4706 | No | ||
99 | GDI2 | 2370068 | 5719 | 0.007 | 0.4684 | No | ||
100 | CSNK2A1 | 1580577 | 5822 | 0.007 | 0.4630 | No | ||
101 | CDC25C | 2570673 4760161 6520707 | 6018 | 0.006 | 0.4526 | No | ||
102 | CFLAR | 2320605 6180440 | 6130 | 0.005 | 0.4466 | No | ||
103 | RAB6A | 3840463 4780731 | 6674 | 0.003 | 0.4172 | No | ||
104 | VEGFC | 5910494 | 6925 | 0.003 | 0.4037 | No | ||
105 | RAB5A | 6520324 | 7144 | 0.002 | 0.3919 | No | ||
106 | SPRY2 | 5860184 | 7170 | 0.002 | 0.3906 | No | ||
107 | MFAP1 | 6660092 | 7281 | 0.002 | 0.3847 | No | ||
108 | ATG5 | 6200433 5360324 | 7589 | 0.001 | 0.3680 | No | ||
109 | BIRC6 | 70148 | 7682 | 0.001 | 0.3630 | No | ||
110 | CRK | 1230162 4780128 | 7696 | 0.001 | 0.3623 | No | ||
111 | EPS15 | 4200215 | 7772 | 0.000 | 0.3583 | No | ||
112 | TIAM2 | 360195 | 7779 | 0.000 | 0.3579 | No | ||
113 | XRCC5 | 7100286 | 7892 | 0.000 | 0.3519 | No | ||
114 | KIF11 | 5390139 | 7948 | -0.000 | 0.3489 | No | ||
115 | MAP3K4 | 5720041 | 8321 | -0.001 | 0.3287 | No | ||
116 | SAMD4A | 1170717 | 8355 | -0.001 | 0.3269 | No | ||
117 | EPS8 | 7050204 | 8774 | -0.002 | 0.3043 | No | ||
118 | JAG1 | 3440390 | 8844 | -0.002 | 0.3006 | No | ||
119 | CTGF | 4540577 | 9135 | -0.003 | 0.2849 | No | ||
120 | NCOA6 | 1780333 6450110 | 9535 | -0.004 | 0.2633 | No | ||
121 | MTIF2 | 2260270 | 9565 | -0.004 | 0.2618 | No | ||
122 | ATF1 | 4570142 5550095 | 9609 | -0.004 | 0.2596 | No | ||
123 | SMARCA5 | 6620050 | 9652 | -0.004 | 0.2574 | No | ||
124 | MAPKAPK5 | 2510601 | 9819 | -0.005 | 0.2484 | No | ||
125 | NPAS2 | 770670 | 9836 | -0.005 | 0.2477 | No | ||
126 | TRIM24 | 7050670 | 9838 | -0.005 | 0.2477 | No | ||
127 | FOSL1 | 430021 | 10299 | -0.006 | 0.2229 | No | ||
128 | FZD1 | 3140215 | 10519 | -0.007 | 0.2111 | No | ||
129 | FBXL7 | 6620711 | 10641 | -0.008 | 0.2047 | No | ||
130 | CDH11 | 1230133 2100180 4610110 | 10824 | -0.008 | 0.1949 | No | ||
131 | IPO7 | 2190746 | 10898 | -0.008 | 0.1911 | No | ||
132 | TRIP4 | 630072 | 11016 | -0.009 | 0.1850 | No | ||
133 | CDK7 | 2640451 | 11027 | -0.009 | 0.1846 | No | ||
134 | MRPL1 | 430626 3130129 5220152 | 11238 | -0.010 | 0.1734 | No | ||
135 | PRKD3 | 5220520 5890519 | 11241 | -0.010 | 0.1734 | No | ||
136 | USP8 | 2640347 3840451 6100672 | 11359 | -0.010 | 0.1673 | No | ||
137 | TDG | 2900358 2940079 | 11377 | -0.011 | 0.1666 | No | ||
138 | CXXC5 | 840010 | 11438 | -0.011 | 0.1635 | No | ||
139 | RBM27 | 4050603 | 11536 | -0.011 | 0.1584 | No | ||
140 | JMJD1C | 940575 2120025 | 11572 | -0.011 | 0.1568 | No | ||
141 | NMI | 520270 | 11624 | -0.012 | 0.1542 | No | ||
142 | THRAP3 | 6180309 | 11717 | -0.012 | 0.1494 | No | ||
143 | NBN | 730538 2470619 4780594 | 12040 | -0.014 | 0.1322 | No | ||
144 | NUFIP1 | 6350241 | 12136 | -0.015 | 0.1273 | No | ||
145 | B4GALT5 | 1230692 | 12656 | -0.019 | 0.0995 | No | ||
146 | OSBP | 5390471 | 12752 | -0.020 | 0.0947 | No | ||
147 | PLK1 | 1780369 2640121 | 12849 | -0.021 | 0.0899 | No | ||
148 | RCC1 | 2480358 | 12888 | -0.022 | 0.0883 | No | ||
149 | CRSP6 | 2940358 | 12942 | -0.022 | 0.0858 | No | ||
150 | HS3ST3B1 | 380040 | 13199 | -0.025 | 0.0724 | No | ||
151 | PLAG1 | 1450142 3870139 6520039 | 13455 | -0.029 | 0.0591 | No | ||
152 | BUB1 | 5390270 | 13478 | -0.029 | 0.0584 | No | ||
153 | PDGFB | 3060440 6370008 | 13639 | -0.032 | 0.0503 | No | ||
154 | GTF2H1 | 2570746 2650148 | 14039 | -0.040 | 0.0294 | No | ||
155 | CORO1C | 4570397 | 14045 | -0.040 | 0.0299 | No | ||
156 | RNF14 | 50402 1340041 6370687 | 14225 | -0.045 | 0.0210 | No | ||
157 | PHF6 | 3120632 3990041 | 14281 | -0.046 | 0.0189 | No | ||
158 | BLZF1 | 630088 | 14327 | -0.048 | 0.0173 | No | ||
159 | HSPE1 | 3170438 | 14405 | -0.050 | 0.0141 | No | ||
160 | EGFR | 4920138 6480521 | 14489 | -0.052 | 0.0105 | No | ||
161 | JMJD2B | 6350372 6400471 | 14649 | -0.057 | 0.0030 | No | ||
162 | FADD | 2360593 4210692 6520019 | 14672 | -0.058 | 0.0029 | No | ||
163 | ANLN | 1780113 2470537 6840047 | 14711 | -0.059 | 0.0019 | No | ||
164 | SNIP1 | 5360092 | 14724 | -0.060 | 0.0024 | No | ||
165 | UBN1 | 5900195 | 14899 | -0.067 | -0.0058 | No | ||
166 | ERCC3 | 6900008 | 14917 | -0.068 | -0.0055 | No | ||
167 | EIF3S10 | 1190079 3840176 | 14940 | -0.069 | -0.0054 | No | ||
168 | MTMR4 | 4540524 | 15000 | -0.072 | -0.0073 | No | ||
169 | DLG5 | 450215 | 15235 | -0.084 | -0.0184 | No | ||
170 | PKN2 | 940746 2350168 | 15248 | -0.085 | -0.0175 | No | ||
171 | PSMA5 | 5390537 | 15296 | -0.088 | -0.0184 | No | ||
172 | PSMC2 | 7040010 | 15638 | -0.116 | -0.0348 | No | ||
173 | TOP1 | 770471 4060632 6650324 | 15704 | -0.123 | -0.0360 | No | ||
174 | SFRS9 | 3800047 | 15791 | -0.131 | -0.0382 | No | ||
175 | ADSL | 5570484 | 15830 | -0.135 | -0.0378 | No | ||
176 | DNAJA2 | 2630253 6860358 | 15886 | -0.142 | -0.0381 | No | ||
177 | ARHGEF2 | 3360577 | 16222 | -0.187 | -0.0528 | No | ||
178 | SON | 3120148 5860239 7040403 | 16252 | -0.192 | -0.0508 | No | ||
179 | PANX1 | 6550632 | 16460 | -0.222 | -0.0579 | No | ||
180 | ZDHHC16 | 4230390 | 16679 | -0.253 | -0.0651 | No | ||
181 | RBM14 | 5340731 5690315 | 16739 | -0.262 | -0.0634 | No | ||
182 | BAG2 | 2900324 | 16758 | -0.266 | -0.0594 | No | ||
183 | ARPC5L | 1090148 | 16959 | -0.302 | -0.0647 | No | ||
184 | UBE2C | 6130017 | 16960 | -0.302 | -0.0591 | No | ||
185 | LHFPL2 | 450020 | 17005 | -0.310 | -0.0557 | No | ||
186 | SLC2A1 | 2100609 | 17320 | -0.375 | -0.0658 | No | ||
187 | BUB3 | 3170546 | 17321 | -0.375 | -0.0588 | No | ||
188 | ARFGAP1 | 4780364 5390358 | 17397 | -0.394 | -0.0556 | No | ||
189 | KIAA0859 | 510497 770722 1340687 6840711 | 17517 | -0.432 | -0.0540 | No | ||
190 | TARDBP | 870390 2350093 | 17715 | -0.494 | -0.0555 | No | ||
191 | MID1IP1 | 2570739 | 18026 | -0.665 | -0.0600 | No | ||
192 | WNT5B | 5080162 | 18253 | -0.907 | -0.0554 | No | ||
193 | HIST1H4B | 4210524 | 18353 | -1.054 | -0.0411 | No | ||
194 | HIST1H4C | 5570528 | 18472 | -1.451 | -0.0206 | No | ||
195 | HSPA8 | 2120315 1050132 6550746 | 18484 | -1.525 | 0.0072 | No |