Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | 0.6308237 |
Normalized Enrichment Score (NES) | 1.641621 |
Nominal p-value | 0.0 |
FDR q-value | 0.07137134 |
FWER p-Value | 0.619 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SIRPA | 130465 5700332 | 54 | 1.848 | 0.0368 | Yes | ||
2 | EMP1 | 4120438 | 60 | 1.755 | 0.0743 | Yes | ||
3 | LBR | 4540671 | 95 | 1.478 | 0.1043 | Yes | ||
4 | HSPH1 | 1690017 | 121 | 1.386 | 0.1328 | Yes | ||
5 | CDC5L | 3130446 3390025 6400204 | 125 | 1.376 | 0.1622 | Yes | ||
6 | ATP2A2 | 1090075 3990279 | 134 | 1.356 | 0.1910 | Yes | ||
7 | HDAC2 | 4050433 | 153 | 1.273 | 0.2174 | Yes | ||
8 | RAP1B | 3710138 | 192 | 1.148 | 0.2400 | Yes | ||
9 | TBK1 | 5690338 | 223 | 1.069 | 0.2614 | Yes | ||
10 | GTF2H2 | 5130358 | 305 | 0.954 | 0.2776 | Yes | ||
11 | DDX21 | 6100446 | 309 | 0.946 | 0.2978 | Yes | ||
12 | SLC4A1AP | 3190576 | 354 | 0.901 | 0.3148 | Yes | ||
13 | RABGAP1 | 5050397 | 368 | 0.884 | 0.3331 | Yes | ||
14 | SMAD4 | 5670519 | 392 | 0.852 | 0.3502 | Yes | ||
15 | RABGGTB | 3120037 | 428 | 0.823 | 0.3660 | Yes | ||
16 | SRPK2 | 6380341 | 440 | 0.812 | 0.3829 | Yes | ||
17 | TMPO | 4050494 | 450 | 0.804 | 0.3997 | Yes | ||
18 | PSMA4 | 4560427 | 485 | 0.771 | 0.4144 | Yes | ||
19 | CCT4 | 6380161 | 506 | 0.758 | 0.4297 | Yes | ||
20 | DDX20 | 3290348 | 552 | 0.721 | 0.4427 | Yes | ||
21 | TOP2A | 360717 | 627 | 0.675 | 0.4533 | Yes | ||
22 | UBE2D2 | 4590671 6510446 | 656 | 0.656 | 0.4658 | Yes | ||
23 | POLD3 | 6400278 | 722 | 0.624 | 0.4758 | Yes | ||
24 | CCNH | 3190347 | 764 | 0.603 | 0.4865 | Yes | ||
25 | RAB1A | 2370671 | 791 | 0.589 | 0.4978 | Yes | ||
26 | PPP2R5E | 70671 2120056 | 801 | 0.583 | 0.5098 | Yes | ||
27 | PCNA | 940754 | 833 | 0.569 | 0.5204 | Yes | ||
28 | EXOC2 | 3190132 | 870 | 0.554 | 0.5304 | Yes | ||
29 | SLC25A17 | 2100369 | 941 | 0.525 | 0.5379 | Yes | ||
30 | PIK3C3 | 6590717 | 1012 | 0.498 | 0.5448 | Yes | ||
31 | MCTS1 | 6130133 | 1100 | 0.460 | 0.5500 | Yes | ||
32 | PPP2CB | 5570593 | 1165 | 0.440 | 0.5560 | Yes | ||
33 | MAP3K7 | 6040068 | 1368 | 0.370 | 0.5530 | Yes | ||
34 | EIF4B | 5390563 5270577 | 1372 | 0.369 | 0.5608 | Yes | ||
35 | MAPK14 | 5290731 | 1417 | 0.354 | 0.5660 | Yes | ||
36 | OGT | 2360131 4610333 | 1440 | 0.350 | 0.5723 | Yes | ||
37 | ZDHHC5 | 1690711 | 1557 | 0.322 | 0.5730 | Yes | ||
38 | FNTA | 70059 | 1609 | 0.303 | 0.5767 | Yes | ||
39 | BCL2L1 | 1580452 4200152 5420484 | 1636 | 0.296 | 0.5817 | Yes | ||
40 | UBE2D3 | 3190452 | 1699 | 0.280 | 0.5844 | Yes | ||
41 | RBM17 | 870592 | 1758 | 0.267 | 0.5870 | Yes | ||
42 | GNL2 | 6620022 | 1773 | 0.263 | 0.5919 | Yes | ||
43 | PSMD12 | 730044 | 1793 | 0.259 | 0.5964 | Yes | ||
44 | SIRT1 | 1190731 | 1801 | 0.257 | 0.6016 | Yes | ||
45 | USP3 | 2060332 | 1862 | 0.242 | 0.6035 | Yes | ||
46 | MAT2A | 4070026 4730079 6020280 | 1915 | 0.232 | 0.6057 | Yes | ||
47 | TXNRD1 | 6590446 | 1920 | 0.230 | 0.6104 | Yes | ||
48 | PRIM2A | 7000692 | 1931 | 0.226 | 0.6147 | Yes | ||
49 | PJA2 | 430537 | 2020 | 0.206 | 0.6144 | Yes | ||
50 | RIPK1 | 3190025 | 2067 | 0.197 | 0.6161 | Yes | ||
51 | MRPL15 | 360390 | 2114 | 0.189 | 0.6177 | Yes | ||
52 | SUPV3L1 | 1170072 | 2124 | 0.187 | 0.6213 | Yes | ||
53 | TNFSF5IP1 | 2060095 | 2148 | 0.182 | 0.6239 | Yes | ||
54 | PPP1CC | 6380300 2510647 | 2165 | 0.179 | 0.6269 | Yes | ||
55 | SNRPG | 2340551 | 2166 | 0.179 | 0.6308 | Yes | ||
56 | ELOVL6 | 5340746 | 2267 | 0.161 | 0.6288 | Yes | ||
57 | RPS7 | 6860113 | 2303 | 0.156 | 0.6303 | Yes | ||
58 | XBP1 | 3840594 | 2353 | 0.148 | 0.6308 | Yes | ||
59 | GTF2B | 6860685 | 2553 | 0.122 | 0.6227 | No | ||
60 | PSMC6 | 2810021 | 2614 | 0.117 | 0.6219 | No | ||
61 | MCM3 | 5570068 | 2691 | 0.107 | 0.6201 | No | ||
62 | MRPL35 | 1990671 | 2810 | 0.097 | 0.6158 | No | ||
63 | TCERG1 | 2350551 4540397 5220746 | 2854 | 0.092 | 0.6155 | No | ||
64 | CLCN7 | 2970095 | 2959 | 0.083 | 0.6116 | No | ||
65 | BIRC2 | 2940435 4730020 | 3059 | 0.076 | 0.6079 | No | ||
66 | STK17B | 130091 | 3191 | 0.067 | 0.6022 | No | ||
67 | GABPB2 | 6130450 7050735 | 3202 | 0.067 | 0.6031 | No | ||
68 | CCNA2 | 5290075 | 3209 | 0.066 | 0.6042 | No | ||
69 | EML4 | 5700373 | 3329 | 0.058 | 0.5990 | No | ||
70 | FBXL3 | 5910142 | 3383 | 0.056 | 0.5974 | No | ||
71 | MYC | 380541 4670170 | 3486 | 0.050 | 0.5929 | No | ||
72 | WEE1 | 3390070 | 3537 | 0.047 | 0.5912 | No | ||
73 | USP12 | 6130735 6620280 | 3562 | 0.046 | 0.5909 | No | ||
74 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 3665 | 0.041 | 0.5863 | No | ||
75 | ARFGEF2 | 5550500 | 3711 | 0.039 | 0.5847 | No | ||
76 | FNDC3A | 2690097 3290044 | 3726 | 0.038 | 0.5847 | No | ||
77 | PSMB1 | 2940402 | 4007 | 0.028 | 0.5702 | No | ||
78 | CDC23 | 3190593 | 4029 | 0.028 | 0.5696 | No | ||
79 | SSFA2 | 3870133 | 4809 | 0.014 | 0.5277 | No | ||
80 | HSPA1L | 4010538 | 4869 | 0.013 | 0.5248 | No | ||
81 | GGPS1 | 840128 2320215 | 5005 | 0.012 | 0.5177 | No | ||
82 | ACSL3 | 3140195 | 5118 | 0.011 | 0.5119 | No | ||
83 | GOPC | 6620400 | 5384 | 0.009 | 0.4977 | No | ||
84 | GDI2 | 2370068 | 5719 | 0.007 | 0.4798 | No | ||
85 | CDC25C | 2570673 4760161 6520707 | 6018 | 0.006 | 0.4637 | No | ||
86 | CFLAR | 2320605 6180440 | 6130 | 0.005 | 0.4578 | No | ||
87 | VEGFC | 5910494 | 6925 | 0.003 | 0.4149 | No | ||
88 | RAB5A | 6520324 | 7144 | 0.002 | 0.4031 | No | ||
89 | SPRY2 | 5860184 | 7170 | 0.002 | 0.4018 | No | ||
90 | MFAP1 | 6660092 | 7281 | 0.002 | 0.3958 | No | ||
91 | SEH1L | 4590563 | 7551 | 0.001 | 0.3813 | No | ||
92 | ATG5 | 6200433 5360324 | 7589 | 0.001 | 0.3793 | No | ||
93 | BIRC6 | 70148 | 7682 | 0.001 | 0.3743 | No | ||
94 | CRK | 1230162 4780128 | 7696 | 0.001 | 0.3736 | No | ||
95 | EPS15 | 4200215 | 7772 | 0.000 | 0.3696 | No | ||
96 | TIAM2 | 360195 | 7779 | 0.000 | 0.3693 | No | ||
97 | XRCC5 | 7100286 | 7892 | 0.000 | 0.3632 | No | ||
98 | EPS8 | 7050204 | 8774 | -0.002 | 0.3155 | No | ||
99 | LYN | 6040600 | 8811 | -0.002 | 0.3136 | No | ||
100 | JAG1 | 3440390 | 8844 | -0.002 | 0.3119 | No | ||
101 | CTGF | 4540577 | 9135 | -0.003 | 0.2962 | No | ||
102 | NCOA6 | 1780333 6450110 | 9535 | -0.004 | 0.2747 | No | ||
103 | MTIF2 | 2260270 | 9565 | -0.004 | 0.2732 | No | ||
104 | SMARCA5 | 6620050 | 9652 | -0.004 | 0.2687 | No | ||
105 | CPT1A | 6350093 | 10012 | -0.006 | 0.2493 | No | ||
106 | FOSL1 | 430021 | 10299 | -0.006 | 0.2340 | No | ||
107 | FZD1 | 3140215 | 10519 | -0.007 | 0.2222 | No | ||
108 | FBXL7 | 6620711 | 10641 | -0.008 | 0.2158 | No | ||
109 | CDH11 | 1230133 2100180 4610110 | 10824 | -0.008 | 0.2062 | No | ||
110 | IPO7 | 2190746 | 10898 | -0.008 | 0.2024 | No | ||
111 | CDK7 | 2640451 | 11027 | -0.009 | 0.1956 | No | ||
112 | IL1RL1 | 3990224 6020347 | 11227 | -0.010 | 0.1851 | No | ||
113 | MRPL1 | 430626 3130129 5220152 | 11238 | -0.010 | 0.1847 | No | ||
114 | PRKD3 | 5220520 5890519 | 11241 | -0.010 | 0.1848 | No | ||
115 | TDG | 2900358 2940079 | 11377 | -0.011 | 0.1777 | No | ||
116 | CXXC5 | 840010 | 11438 | -0.011 | 0.1747 | No | ||
117 | RBM27 | 4050603 | 11536 | -0.011 | 0.1697 | No | ||
118 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 11543 | -0.011 | 0.1696 | No | ||
119 | THRAP3 | 6180309 | 11717 | -0.012 | 0.1605 | No | ||
120 | NUFIP1 | 6350241 | 12136 | -0.015 | 0.1382 | No | ||
121 | B4GALT5 | 1230692 | 12656 | -0.019 | 0.1105 | No | ||
122 | RCC1 | 2480358 | 12888 | -0.022 | 0.0984 | No | ||
123 | CRSP6 | 2940358 | 12942 | -0.022 | 0.0960 | No | ||
124 | HS3ST3B1 | 380040 | 13199 | -0.025 | 0.0827 | No | ||
125 | PLAG1 | 1450142 3870139 6520039 | 13455 | -0.029 | 0.0695 | No | ||
126 | BUB1 | 5390270 | 13478 | -0.029 | 0.0689 | No | ||
127 | PDGFB | 3060440 6370008 | 13639 | -0.032 | 0.0609 | No | ||
128 | GTF2H1 | 2570746 2650148 | 14039 | -0.040 | 0.0402 | No | ||
129 | CORO1C | 4570397 | 14045 | -0.040 | 0.0408 | No | ||
130 | RNF14 | 50402 1340041 6370687 | 14225 | -0.045 | 0.0320 | No | ||
131 | BLZF1 | 630088 | 14327 | -0.048 | 0.0276 | No | ||
132 | GCNT1 | 940129 1780215 2370253 | 14394 | -0.049 | 0.0251 | No | ||
133 | HSPE1 | 3170438 | 14405 | -0.050 | 0.0256 | No | ||
134 | PAPPA | 4230463 | 14537 | -0.054 | 0.0197 | No | ||
135 | JMJD2B | 6350372 6400471 | 14649 | -0.057 | 0.0149 | No | ||
136 | FADD | 2360593 4210692 6520019 | 14672 | -0.058 | 0.0149 | No | ||
137 | ANLN | 1780113 2470537 6840047 | 14711 | -0.059 | 0.0142 | No | ||
138 | SNIP1 | 5360092 | 14724 | -0.060 | 0.0148 | No | ||
139 | ERCC3 | 6900008 | 14917 | -0.068 | 0.0058 | No | ||
140 | EIF3S10 | 1190079 3840176 | 14940 | -0.069 | 0.0061 | No | ||
141 | MTMR4 | 4540524 | 15000 | -0.072 | 0.0045 | No | ||
142 | CHST2 | 3180682 | 15005 | -0.072 | 0.0058 | No | ||
143 | FAS | 4480112 6110040 | 15009 | -0.072 | 0.0072 | No | ||
144 | DLG5 | 450215 | 15235 | -0.084 | -0.0032 | No | ||
145 | PSMA5 | 5390537 | 15296 | -0.088 | -0.0045 | No | ||
146 | TOP1 | 770471 4060632 6650324 | 15704 | -0.123 | -0.0240 | No | ||
147 | SFRS9 | 3800047 | 15791 | -0.131 | -0.0258 | No | ||
148 | ADSL | 5570484 | 15830 | -0.135 | -0.0249 | No | ||
149 | DNAJA2 | 2630253 6860358 | 15886 | -0.142 | -0.0249 | No | ||
150 | ARHGEF2 | 3360577 | 16222 | -0.187 | -0.0390 | No | ||
151 | SON | 3120148 5860239 7040403 | 16252 | -0.192 | -0.0364 | No | ||
152 | PANX1 | 6550632 | 16460 | -0.222 | -0.0429 | No | ||
153 | FKBP1A | 2450368 | 16505 | -0.228 | -0.0404 | No | ||
154 | ZDHHC16 | 4230390 | 16679 | -0.253 | -0.0443 | No | ||
155 | RBM14 | 5340731 5690315 | 16739 | -0.262 | -0.0419 | No | ||
156 | BAG2 | 2900324 | 16758 | -0.266 | -0.0371 | No | ||
157 | UBE2C | 6130017 | 16960 | -0.302 | -0.0415 | No | ||
158 | LHFPL2 | 450020 | 17005 | -0.310 | -0.0372 | No | ||
159 | SLC2A1 | 2100609 | 17320 | -0.375 | -0.0462 | No | ||
160 | BUB3 | 3170546 | 17321 | -0.375 | -0.0381 | No | ||
161 | ARFGAP1 | 4780364 5390358 | 17397 | -0.394 | -0.0337 | No | ||
162 | KIAA0859 | 510497 770722 1340687 6840711 | 17517 | -0.432 | -0.0309 | No | ||
163 | TARDBP | 870390 2350093 | 17715 | -0.494 | -0.0309 | No | ||
164 | GIPC1 | 4590348 5570438 5900707 | 17922 | -0.598 | -0.0292 | No | ||
165 | MID1IP1 | 2570739 | 18026 | -0.665 | -0.0205 | No | ||
166 | WNT5B | 5080162 | 18253 | -0.907 | -0.0132 | No | ||
167 | HSPA8 | 2120315 1050132 6550746 | 18484 | -1.525 | 0.0072 | No |