Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | 0.76221395 |
| Normalized Enrichment Score (NES) | 1.6384982 |
| Nominal p-value | 0.008230452 |
| FDR q-value | 0.07237007 |
| FWER p-Value | 0.649 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MCM4 | 2760673 5420711 | 68 | 1.651 | 0.0874 | Yes | ||
| 2 | CDK2 | 130484 2260301 4010088 5050110 | 84 | 1.554 | 0.1722 | Yes | ||
| 3 | MCM6 | 60092 540181 6510110 | 128 | 1.370 | 0.2455 | Yes | ||
| 4 | CDC7 | 4060546 4850041 | 133 | 1.359 | 0.3202 | Yes | ||
| 5 | RFC4 | 3800082 6840142 | 145 | 1.314 | 0.3921 | Yes | ||
| 6 | RFC5 | 3800452 6020091 | 236 | 1.048 | 0.4451 | Yes | ||
| 7 | ORC6L | 2260592 | 333 | 0.923 | 0.4908 | Yes | ||
| 8 | CDC6 | 4570296 5360600 | 400 | 0.848 | 0.5340 | Yes | ||
| 9 | RPA3 | 5700136 | 630 | 0.672 | 0.5587 | Yes | ||
| 10 | POLD3 | 6400278 | 722 | 0.624 | 0.5883 | Yes | ||
| 11 | PCNA | 940754 | 833 | 0.569 | 0.6137 | Yes | ||
| 12 | POLE | 6020538 | 872 | 0.554 | 0.6422 | Yes | ||
| 13 | RFC1 | 1190673 | 888 | 0.547 | 0.6716 | Yes | ||
| 14 | RPA1 | 360452 | 914 | 0.539 | 0.7000 | Yes | ||
| 15 | NACA | 520326 5890673 | 1273 | 0.400 | 0.7028 | Yes | ||
| 16 | ORC5L | 1940133 1940711 | 1454 | 0.347 | 0.7122 | Yes | ||
| 17 | RFC3 | 1980600 | 1527 | 0.329 | 0.7265 | Yes | ||
| 18 | CDC45L | 70537 3130114 | 1679 | 0.285 | 0.7341 | Yes | ||
| 19 | UBC | 1190129 1570161 5390079 6770097 7100500 | 1765 | 0.266 | 0.7442 | Yes | ||
| 20 | PRIM1 | 6420746 | 1785 | 0.261 | 0.7576 | Yes | ||
| 21 | PRIM2A | 7000692 | 1931 | 0.226 | 0.7622 | Yes | ||
| 22 | GMNN | 2630148 | 2370 | 0.146 | 0.7467 | No | ||
| 23 | MCM3 | 5570068 | 2691 | 0.107 | 0.7354 | No | ||
| 24 | MCM7 | 3290292 5220056 | 2733 | 0.103 | 0.7389 | No | ||
| 25 | CDT1 | 3780682 | 2887 | 0.090 | 0.7356 | No | ||
| 26 | ORC3L | 3060348 | 3171 | 0.068 | 0.7241 | No | ||
| 27 | ORC2L | 1990470 6510019 | 3821 | 0.035 | 0.6911 | No | ||
| 28 | ORC4L | 4230538 5550288 | 4055 | 0.027 | 0.6800 | No | ||
| 29 | POLA2 | 940519 | 4200 | 0.023 | 0.6735 | No | ||
| 30 | UBB | 4810138 | 5647 | 0.008 | 0.5961 | No | ||
| 31 | UBA52 | 6180288 | 6453 | 0.004 | 0.5530 | No | ||
| 32 | RPS27A | 510717 | 6484 | 0.004 | 0.5516 | No | ||
| 33 | POLE2 | 6110041 | 9910 | -0.005 | 0.3675 | No | ||
| 34 | MCM10 | 4920632 | 10531 | -0.007 | 0.3346 | No | ||
| 35 | MCM2 | 5050139 | 12705 | -0.020 | 0.2187 | No | ||
| 36 | POLD2 | 6400148 | 13931 | -0.038 | 0.1548 | No | ||
| 37 | MCM5 | 2680647 | 15739 | -0.127 | 0.0645 | No | ||
| 38 | ORC1L | 2370328 6110390 | 16154 | -0.179 | 0.0521 | No | ||
| 39 | RPA2 | 2760301 5420195 | 16845 | -0.280 | 0.0304 | No | ||
| 40 | POLD1 | 4830026 | 17073 | -0.322 | 0.0359 | No | ||
| 41 | POLD4 | 2320082 | 18217 | -0.854 | 0.0215 | No |
