Details for gene set REACTOME_SIGNALING_BY

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	REACTOME_SIGNALING_BY_GPCR
Enrichment Score (ES)	-0.60321623
Normalized Enrichment Score (NES)	-1.5063969
Nominal p-value	0.0037453184
FDR q-value	0.45966208
FWER p-Value	0.999

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GNA13	4590102	623	0.677	0.0019	No
2	PDPK1	6650168	1017	0.496	0.0068	No
3	GNB1	2120397	1309	0.386	0.0114	No
4	CCL5	3710397	1562	0.321	0.0146	No
5	LTB4R	1770056	1690	0.282	0.0226	No
6	RAMP1	2320168	1710	0.276	0.0361	No
7	ROCK1	130044	1967	0.218	0.0337	No
8	P2RY6	5290400	2435	0.137	0.0157	No
9	GNG2	2230390	2449	0.135	0.0221	No
10	PIK3CG	5890110	2562	0.122	0.0224	No
11	P2RY10	6370039 6840204	2616	0.117	0.0257	No
12	F2R	4810180	2696	0.107	0.0270	No
13	CCL25	450541 540435	2948	0.084	0.0179	No
14	PTGER3	2900739 6770750	3275	0.062	0.0035	No
15	PDE4D	2470528 6660014	3446	0.052	-0.0029	No
16	SCT	2230348	3744	0.038	-0.0170	No
17	AVP	2100113	3908	0.032	-0.0242	No
18	IL8RB	450592 1170537	4225	0.023	-0.0401	No
19	PTGER2	3170039	4400	0.019	-0.0485	No
20	ADCY6	450364 6290670 6940286	4448	0.018	-0.0501	No
21	XCL1	3800504	4457	0.018	-0.0496	No
22	KISS1	1580398	4505	0.018	-0.0512	No
23	CXCL11	1090551	4541	0.017	-0.0522	No
24	CXCR6	3190440	4804	0.014	-0.0656	No
25	OPN1SW	6420377	4893	0.013	-0.0697	No
26	DRD1	430025	5090	0.011	-0.0798	No
27	GLP1R	6420528	5135	0.011	-0.0816	No
28	CALCA	5860167	5339	0.009	-0.0921	No
29	ADCYAP1	520086	5383	0.009	-0.0940	No
30	BAI3	940692	5512	0.008	-0.1005	No
31	PLCB2	360132	5520	0.008	-0.1004	No
32	VIP	2850647	5562	0.008	-0.1022	No
33	CCR10	4050097	5569	0.008	-0.1021	No
34	GIP	3170364	5640	0.008	-0.1055	No
35	ADM2	4060102	5838	0.007	-0.1158	No
36	GNGT1	5220156	5866	0.006	-0.1169	No
37	C5AR1	4540402	5928	0.006	-0.1199	No
38	PIK3CA	6220129	5975	0.006	-0.1221	No
39	ADRA1D	380035 540025	6234	0.005	-0.1358	No
40	SSTR1	2630471	6414	0.004	-0.1452	No
41	XCR1	5080072	6456	0.004	-0.1472	No
42	PTGDR	3850161	6513	0.004	-0.1501	No
43	HCRTR1	1580273	6561	0.004	-0.1524	No
44	GPRC6A	4560576	6605	0.004	-0.1545	No
45	TACR1	70358 3840411	6667	0.004	-0.1576	No
46	LHCGR	4560465 5860551	7000	0.002	-0.1755	No
47	PPY	2340373	7121	0.002	-0.1819	No
48	CRH	3710301	7183	0.002	-0.1851	No
49	CALCR	1690494	7204	0.002	-0.1860	No
50	NTS	380300 2120592	7341	0.002	-0.1933	No
51	CCK	6370368	7345	0.002	-0.1934	No
52	AKT1	5290746	7384	0.001	-0.1954	No
53	TACR2	1740358	7671	0.001	-0.2108	No
54	MTNR1A	380204	7702	0.001	-0.2124	No
55	CGA	630403	7770	0.000	-0.2160	No
56	CALCRL	4280035	7966	-0.000	-0.2266	No
57	HTR6	4850022	8052	-0.000	-0.2312	No
58	GRPR	6020170	8154	-0.000	-0.2366	No
59	PTGER1	6100132	8205	-0.001	-0.2393	No
60	SST	6590142	8260	-0.001	-0.2422	No
61	OPRM1	5360279	8473	-0.001	-0.2536	No
62	PPYR1	1410072	8566	-0.002	-0.2585	No
63	EDN1	1770047	8742	-0.002	-0.2678	No
64	CCR6	5720368 6020176	9058	-0.003	-0.2847	No
65	AVPR1A	2120300	9113	-0.003	-0.2875	No
66	ADRA2A	5340520	9334	-0.004	-0.2992	No
67	MC2R	2970504	9388	-0.004	-0.3019	No
68	CHRM2	870750	9448	-0.004	-0.3049	No
69	LHB	1450368	9467	-0.004	-0.3057	No
70	GNA14	3390017	9521	-0.004	-0.3083	No
71	DRD3	4780402	9893	-0.005	-0.3281	No
72	FSHB	7100592	9908	-0.005	-0.3286	No
73	PIK3R1	4730671	9923	-0.005	-0.3291	No
74	TAC1	7000195 380706	9968	-0.005	-0.3312	No
75	GALR1	6020452	10191	-0.006	-0.3429	No
76	PTGFR	3850373	10192	-0.006	-0.3426	No
77	P2RY4	630053	10402	-0.007	-0.3535	No
78	GHRH	4570575	10462	-0.007	-0.3563	No
79	TSHR	1190687 5270364	10721	-0.008	-0.3699	No
80	HCRT	2970463	10755	-0.008	-0.3712	No
81	CCR3	50427	10780	-0.008	-0.3721	No
82	TACR3	4780017	10811	-0.008	-0.3733	No
83	CASR	610504	10815	-0.008	-0.3730	No
84	HCRTR2	2350463	10833	-0.008	-0.3735	No
85	CCKBR	2760128	10913	-0.009	-0.3773	No
86	HTR1F	670148	10973	-0.009	-0.3801	No
87	OXT	3850692	11047	-0.009	-0.3836	No
88	CGB	580273	11057	-0.009	-0.3836	No
89	HRH1	840100	11060	-0.009	-0.3832	No
90	FSHR	610041 7040121	11143	-0.009	-0.3871	No
91	DARC	3940050	11233	-0.010	-0.3914	No
92	NPFF	2030280	11272	-0.010	-0.3930	No
93	AGTR1	4780524 2680592	11345	-0.010	-0.3963	No
94	GNAQ	430670 4210131 5900736	11405	-0.011	-0.3990	No
95	CHRM5	5390333	11514	-0.011	-0.4042	No
96	IL8RA	1580100	11646	-0.012	-0.4107	No
97	GCG	6220735	11813	-0.013	-0.4190	No
98	GLP2R	4150577 5290273 7050095	11926	-0.013	-0.4243	No
99	PNOC	1990114	11962	-0.014	-0.4255	No
100	GNAT1	5270048 6100170	12035	-0.014	-0.4287	No
101	CX3CL1	3990707	12044	-0.014	-0.4283	No
102	ADORA1	6370520	12105	-0.015	-0.4308	No
103	P2RY1	6040121	12265	-0.016	-0.4386	No
104	KNG1	6400576 6770347	12499	-0.018	-0.4503	No
105	GCGR	6620497	12524	-0.018	-0.4506	No
106	AVPR2	360064	12757	-0.020	-0.4621	No
107	TSHB	6770500	12764	-0.020	-0.4613	No
108	GRM6	2030398	12927	-0.022	-0.4690	No
109	HTR2A	360037 6330255	13104	-0.024	-0.4772	No
110	AGT	7000575	13334	-0.027	-0.4882	No
111	P2RY2	2640180 2810128	13388	-0.028	-0.4896	No
112	MC5R	2640176	13413	-0.028	-0.4894	No
113	GHRHR	3130500 4010154	13433	-0.028	-0.4890	No
114	ADCYAP1R1	3390020 4280184 5360180	13582	-0.031	-0.4953	No
115	VIPR2	6520050	13583	-0.031	-0.4937	No
116	PTGIR	2100563	13831	-0.036	-0.5052	No
117	GRK5	1940348 4670053	14000	-0.039	-0.5122	No
118	CRHR2	4590672	14078	-0.041	-0.5142	No
119	IAPP	4230040	14165	-0.043	-0.5166	No
120	GNAZ	6130296	14178	-0.044	-0.5149	No
121	P2RY14	6100497	14215	-0.045	-0.5145	No
122	SCTR	2940070	14990	-0.071	-0.5527	No
123	BDKRB1	730592	15016	-0.073	-0.5502	No
124	ADORA2A	1990687	15332	-0.090	-0.5625	No
125	PDYN	5720408	15587	-0.112	-0.5704	No
126	EDNRA	6900133	15620	-0.114	-0.5661	No
127	HRH2	3840440	15833	-0.135	-0.5704	No
128	GPR17	5890671	15926	-0.146	-0.5677	No
129	NTSR1	6510136	15931	-0.148	-0.5602	No
130	NMB	3360735	16676	-0.252	-0.5871	Yes
131	F2	5720280	16781	-0.270	-0.5785	Yes
132	GNA12	1230301	17238	-0.355	-0.5845	Yes
133	CCR7	2060687	17376	-0.388	-0.5715	Yes
134	ADRBK1	1340333	17453	-0.412	-0.5539	Yes
135	TBXA2R	2370292 3940066	17508	-0.429	-0.5342	Yes
136	RHOG	6760575	18142	-0.778	-0.5275	Yes
137	CNR2	2760398	18201	-0.835	-0.4867	Yes
138	ADRB2	3290373	18208	-0.843	-0.4426	Yes
139	GNAS	630441 1850373 4050152	18457	-1.366	-0.3841	Yes
140	RHOA	580142 5900131 5340450	18598	-3.530	-0.2058	Yes
141	GAL	3930279	18601	-3.926	0.0008	Yes